ZA200504522B - Antibody ("11C7") anti nogo and its pharmaceutical use - Google Patents
Antibody ("11C7") anti nogo and its pharmaceutical use Download PDFInfo
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- ZA200504522B ZA200504522B ZA200504522A ZA200504522A ZA200504522B ZA 200504522 B ZA200504522 B ZA 200504522B ZA 200504522 A ZA200504522 A ZA 200504522A ZA 200504522 A ZA200504522 A ZA 200504522A ZA 200504522 B ZA200504522 B ZA 200504522B
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Classifications
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- C—CHEMISTRY; METALLURGY
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A—HUMAN NECESSITIES
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Engineering & Computer Science (AREA)
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- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
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- Biophysics (AREA)
- Biochemistry (AREA)
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- Psychiatry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Epidemiology (AREA)
- Psychology (AREA)
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- Mycology (AREA)
- Hospice & Palliative Care (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
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GBGB0228832.2A GB0228832D0 (en) | 2002-12-10 | 2002-12-10 | Organic compound |
Publications (1)
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ZA200504522B true ZA200504522B (en) | 2006-03-29 |
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ZA200504522A ZA200504522B (en) | 2002-12-10 | 2006-02-08 | Antibody ("11C7") anti nogo and its pharmaceutical use |
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US (2) | US7785593B2 (ja) |
EP (1) | EP1572745B1 (ja) |
JP (1) | JP4504200B2 (ja) |
KR (1) | KR101215801B1 (ja) |
CN (1) | CN100384877C (ja) |
AT (1) | ATE475671T1 (ja) |
AU (1) | AU2003289998B2 (ja) |
BR (1) | BR0317161A (ja) |
CA (1) | CA2509068C (ja) |
CY (1) | CY1110848T1 (ja) |
DE (1) | DE60333585D1 (ja) |
DK (1) | DK1572745T3 (ja) |
EC (1) | ECSP055849A (ja) |
ES (1) | ES2349293T3 (ja) |
GB (1) | GB0228832D0 (ja) |
HK (1) | HK1084676A1 (ja) |
IL (1) | IL169018A (ja) |
MX (1) | MXPA05006265A (ja) |
NO (1) | NO20053304L (ja) |
PL (1) | PL210720B1 (ja) |
PT (1) | PT1572745E (ja) |
RU (1) | RU2350623C2 (ja) |
SI (1) | SI1572745T1 (ja) |
WO (1) | WO2004052932A2 (ja) |
ZA (1) | ZA200504522B (ja) |
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GB0228832D0 (en) | 2002-12-10 | 2003-01-15 | Novartis Ag | Organic compound |
GB0321997D0 (en) * | 2003-09-19 | 2003-10-22 | Novartis Ag | Organic compound |
PT1711530E (pt) * | 2003-12-22 | 2009-10-22 | Glaxo Group Ltd | Imunoglobulinas neutralizantes de nogo-a para o tratamento de doenças neurológicas |
KR20080030960A (ko) * | 2005-07-05 | 2008-04-07 | 글락소 그룹 리미티드 | Nogo―a에 특이적인 인간화된 항체 및 이의 약제학적용도 |
GB0525662D0 (en) | 2005-12-16 | 2006-01-25 | Glaxo Group Ltd | Immunoglobulins |
NZ584911A (en) * | 2007-11-02 | 2011-08-26 | Novartis Ag | Improved nogo-a binding molecules and pharmaceutical use thereof |
WO2010004031A2 (en) * | 2008-07-11 | 2010-01-14 | Glaxo Group Limited | Novel treatment |
WO2012004773A1 (en) | 2010-07-09 | 2012-01-12 | Universite De Geneve | New uses of nogo-a inhibitors and related methods |
EP2870177A1 (en) | 2012-07-05 | 2015-05-13 | Glaxo Group Limited | Optimum dose regime of an anti-nogo-a antibody in the treatment of amyotrophic lateral sclerosis |
US9534044B2 (en) * | 2013-02-28 | 2017-01-03 | United Arab Emirates University | Alpha-synuclein antibodies and uses thereof |
CA2915250A1 (en) * | 2013-06-13 | 2015-01-08 | Biomatrica, Inc. | Cell stabilization |
IL296874A (en) | 2016-03-01 | 2022-11-01 | Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd | Antibodies specific for the human poliovirus receptor |
AU2020370751A1 (en) | 2019-10-24 | 2022-06-09 | Novago Therapeutics Ag | Novel anti-Nogo-A antibodies |
Family Cites Families (17)
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GB8308573D0 (en) | 1983-03-29 | 1983-05-05 | British Nuclear Fuels Ltd | Filament impregnating/coating |
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
GB8607679D0 (en) | 1986-03-27 | 1986-04-30 | Winter G P | Recombinant dna product |
WO1988001649A1 (en) | 1986-09-02 | 1988-03-10 | Genex Corporation | Single polypeptide chain binding molecules |
IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
US5180820A (en) | 1989-08-30 | 1993-01-19 | Barde Yves Alain | Brain-derived neurotrophic factor |
JP3854306B2 (ja) * | 1991-03-06 | 2006-12-06 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング | ヒト化及びキメラモノクローナル抗体 |
EP1098972B1 (en) | 1998-07-22 | 2010-09-29 | SmithKline Beecham Limited | Protein similar to neuroendocrine-specific protein, and encoding cdna |
SK287323B6 (sk) | 1998-11-06 | 2010-07-07 | University Of Z�Rich | Nogo proteín, jeho purifikovaný fragment, chimérny proteín a purifikovaná molekula s jeho obsahom, izolovaná nukleová kyselina, vektor s jej obsahom, rekombinantná bunka, spôsob produkcie rekombinantného proteínu a jeho použitie |
CU22921A1 (es) | 1999-11-16 | 2004-02-20 | Centro Inmunologia Molecular | Anticuerpos quimérico, humanizado y el fragmento de tipo fv de cadena sencilla que reconoce el antígeno c2. su uso en el diagnóstico y tratamiento de tumores colorrectales |
GEP20063830B (en) * | 2000-01-12 | 2006-05-25 | Univ Yale | Nogo Receptor-Mediated Blockade of Axonal Growth |
DE60230736D1 (de) | 2001-04-30 | 2009-02-26 | Lilly Co Eli | HUMANISIERTE ANTIKÖRPER DIE DAS BETA-AMYLOID PEPTID ERKENNEN& x9; |
DE20110806U1 (de) | 2001-06-29 | 2001-12-20 | Jack Wolfskin Ausrüstung für Draussen GmbH, 65510 Idstein | Zelt |
EP2990394A1 (en) * | 2001-11-30 | 2016-03-02 | Biogen MA Inc. | Antibodies against monocyte chemotactic proteins |
GB0228832D0 (en) | 2002-12-10 | 2003-01-15 | Novartis Ag | Organic compound |
PT1711530E (pt) * | 2003-12-22 | 2009-10-22 | Glaxo Group Ltd | Imunoglobulinas neutralizantes de nogo-a para o tratamento de doenças neurológicas |
US7596225B2 (en) * | 2005-06-30 | 2009-09-29 | Alcatl-Lucent Usa Inc. | Method for refreshing a pairwise master key |
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2002
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- 2003-12-09 DE DE60333585T patent/DE60333585D1/de not_active Expired - Lifetime
- 2003-12-09 PT PT03782350T patent/PT1572745E/pt unknown
- 2003-12-09 PL PL377506A patent/PL210720B1/pl unknown
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2006
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2010
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