ZA200410410B - New etonogestrel esters. - Google Patents

New etonogestrel esters.

Info

Publication number
ZA200410410B
ZA200410410B ZA200410410A ZA200410410A ZA200410410B ZA 200410410 B ZA200410410 B ZA 200410410B ZA 200410410 A ZA200410410 A ZA 200410410A ZA 200410410 A ZA200410410 A ZA 200410410A ZA 200410410 B ZA200410410 B ZA 200410410B
Authority
ZA
South Africa
Prior art keywords
new
etonogestrel esters
esters
new etonogestrel
etonogestrel
Prior art date
Application number
ZA200410410A
Other languages
English (en)
Inventor
Henrik De Nijs
Dirk Leysen
Hendrikus Adrianus Anton Voort
Arij Jan Grootenhuis
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of ZA200410410B publication Critical patent/ZA200410410B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0051Estrane derivatives
    • C07J1/0081Substituted in position 17 alfa and 17 beta
    • C07J1/0088Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
    • C07J1/0096Alkynyl derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16Masculine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34Gestagens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA200410410A 2002-05-30 2004-12-23 New etonogestrel esters. ZA200410410B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02077119 2002-05-30

Publications (1)

Publication Number Publication Date
ZA200410410B true ZA200410410B (en) 2006-02-22

Family

ID=29595014

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200410410A ZA200410410B (en) 2002-05-30 2004-12-23 New etonogestrel esters.

Country Status (31)

Country Link
US (1) US7323454B2 (fr)
EP (1) EP1513861B1 (fr)
JP (1) JP4716726B2 (fr)
KR (1) KR20050009723A (fr)
CN (2) CN1314701C (fr)
AR (1) AR040130A1 (fr)
AT (1) ATE349458T1 (fr)
AU (1) AU2003238081B2 (fr)
BR (1) BR0311254A (fr)
CA (1) CA2487722C (fr)
CO (1) CO5631449A2 (fr)
DE (1) DE60310714T2 (fr)
DK (1) DK1513861T3 (fr)
ES (1) ES2277085T3 (fr)
HK (1) HK1072609A1 (fr)
HR (1) HRP20041101A2 (fr)
IL (1) IL165087A0 (fr)
IS (1) IS2421B (fr)
MX (1) MXPA04011797A (fr)
NO (1) NO20044898L (fr)
NZ (1) NZ536619A (fr)
PE (1) PE20040068A1 (fr)
PL (1) PL373855A1 (fr)
PT (1) PT1513861E (fr)
RS (1) RS97604A (fr)
RU (1) RU2325910C2 (fr)
SI (1) SI1513861T1 (fr)
TW (1) TW200403065A (fr)
UA (1) UA80126C2 (fr)
WO (1) WO2003102012A2 (fr)
ZA (1) ZA200410410B (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200400041A (en) * 2002-05-30 2004-01-01 Akzo Nobel Nv Use of new etonogestrel esters
EP1909973B1 (fr) 2005-07-15 2018-08-22 Micell Technologies, Inc. Enrobages polymeres renfermant de la poudre de medicament a morphologie commandee
US20090062909A1 (en) 2005-07-15 2009-03-05 Micell Technologies, Inc. Stent with polymer coating containing amorphous rapamycin
EP2944382A1 (fr) 2006-04-26 2015-11-18 Micell Technologies, Inc. Revêtements contenant plusieurs médicaments
EP2111184B1 (fr) 2007-01-08 2018-07-25 Micell Technologies, Inc. Stents comportant des couches biodégradables
US11426494B2 (en) 2007-01-08 2022-08-30 MT Acquisition Holdings LLC Stents having biodegradable layers
AU2009251504B2 (en) 2008-04-17 2013-09-05 Micell Technologies, Inc. Stents having bioabsorbable layers
US9510856B2 (en) 2008-07-17 2016-12-06 Micell Technologies, Inc. Drug delivery medical device
CN102159257B (zh) 2008-07-17 2015-11-25 米歇尔技术公司 药物递送医疗设备
US20100239635A1 (en) 2009-03-23 2010-09-23 Micell Technologies, Inc. Drug delivery medical device
CA2757276C (fr) 2009-04-01 2017-06-06 Micell Technologies, Inc. Endoprotheses enduites
EP3366326A1 (fr) 2009-04-17 2018-08-29 Micell Technologies, Inc. Endoprothèses vasculaires ayant une élution contrôlée
US11369498B2 (en) 2010-02-02 2022-06-28 MT Acquisition Holdings LLC Stent and stent delivery system with improved deliverability
WO2011133655A1 (fr) 2010-04-22 2011-10-27 Micell Technologies, Inc. Endoprothèses et autres dispositifs ayant un revêtement de matrice extracellulaire
EP2593039B1 (fr) 2010-07-16 2022-11-30 Micell Technologies, Inc. Dispositif médical d'administration de médicament
WO2013012689A1 (fr) 2011-07-15 2013-01-24 Micell Technologies, Inc. Dispositif médical d'administration de médicament
US10188772B2 (en) 2011-10-18 2019-01-29 Micell Technologies, Inc. Drug delivery medical device
KR20150143476A (ko) 2013-03-12 2015-12-23 미셀 테크놀로지즈, 인코포레이티드 생흡수성 생체의학적 임플란트
JP2016519965A (ja) 2013-05-15 2016-07-11 マイセル・テクノロジーズ,インコーポレイテッド 生体吸収性バイオメディカルインプラント
RU2595818C1 (ru) * 2015-05-25 2016-08-27 Федеральное государственное бюджетное научное учреждение "Научный центр проблем здоровья семьи и репродукции человека" Способ комплексного лечения дисфункции яичников при применении гормонального контрацептива имплантата "импланона"
CN111057120B (zh) * 2019-12-27 2021-04-27 苏州翔实医药发展有限公司 一种依托孕烯衍生物a及其制备方法和用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB845442A (en) 1956-03-22 1960-08-24 Schering Ag Manufacture of steroid compounds
DE1013284B (de) 1956-03-22 1957-08-08 Schering Ag Verfahren zur Einfuehrung der Reste wenig reaktionsfaehiger Carbonsaeuren, insbesondere des ª‰-Cyclopentyl-propionylrestes, in die 17ª‡-staendige Oxygruppe solcher Steroide, die am Kohlenstoffatom 17 neben der Oxygruppe eine Acetylgruppe tragen
GB8313921D0 (en) 1983-05-19 1983-06-22 World Health Org Contraceptive compositions
DE4227989A1 (de) 1992-08-21 1994-06-09 Schering Ag Mittel zur transdermalen Applikation enthaltend 3-Keto-desogestrel
DE4240806A1 (de) 1992-12-01 1994-06-09 Schering Ag Mittel zur transdermalen Applikation enthaltend 14alpha,17alpha-Ethanoestra-1,3,5(10)-trien-3,17beta-diol
JPH07101884A (ja) 1993-10-01 1995-04-18 Sanei Gen F F I Inc 水溶性ヘミセルロースを含有する製剤
HUT75159A (en) * 1993-12-27 1997-04-28 Akzo Nobel Nv Percutaneously absorbable preparation, containing 3-ketodesogestrel and 17 beta-estradiol
DE19613698A1 (de) 1995-07-17 1997-01-23 Schering Ag Mittel zur transdermalen Applikation enthaltend Ester des 13-Ethyl-17ß-hydroxy-11-methylen-18,19-dinor-17alpha-pregn-4-en-20-yn-3-ons
WO1997003709A1 (fr) 1995-07-17 1997-02-06 Schering Aktiengesellschaft Agent pour application transdermique contenant des esters de 3-ketodesogestrel
ID27260A (id) 1998-06-19 2001-03-22 Akzo Nobel Nv Turunan testosteron
WO1999067270A1 (fr) 1998-06-19 1999-12-29 Akzo Nobel N.V. Esters d'acide cycloalkyl-carboxylique de 7.alpha.methyl-estr-4-en-3-one 17.beta.-ol (19-nor 7.alpha-methyltestosterone)
US6180682B1 (en) * 1999-01-26 2001-01-30 Virgil A. Place Buccal drug delivery system for use in male contraception
TW200400041A (en) * 2002-05-30 2004-01-01 Akzo Nobel Nv Use of new etonogestrel esters

Also Published As

Publication number Publication date
SI1513861T1 (sl) 2007-06-30
CN1692122A (zh) 2005-11-02
NO20044898L (no) 2005-02-25
UA80126C2 (en) 2007-08-27
CA2487722C (fr) 2011-07-19
DE60310714T2 (de) 2007-10-11
PT1513861E (pt) 2007-03-30
US7323454B2 (en) 2008-01-29
JP4716726B2 (ja) 2011-07-06
TW200403065A (en) 2004-03-01
PL373855A1 (en) 2005-09-19
CN101100480A (zh) 2008-01-09
EP1513861B1 (fr) 2006-12-27
CA2487722A1 (fr) 2003-12-11
AU2003238081A1 (en) 2003-12-19
CO5631449A2 (es) 2006-04-28
WO2003102012A2 (fr) 2003-12-11
KR20050009723A (ko) 2005-01-25
HRP20041101A2 (en) 2004-12-31
HK1072609A1 (en) 2005-09-02
MXPA04011797A (es) 2005-03-31
NZ536619A (en) 2007-09-28
AU2003238081B2 (en) 2008-09-18
EP1513861A2 (fr) 2005-03-16
ES2277085T3 (es) 2007-07-01
PE20040068A1 (es) 2004-02-18
WO2003102012A9 (fr) 2005-01-13
JP2005532350A (ja) 2005-10-27
RS97604A (en) 2006-10-27
ATE349458T1 (de) 2007-01-15
BR0311254A (pt) 2005-03-15
RU2325910C2 (ru) 2008-06-10
RU2004138807A (ru) 2005-05-27
IS2421B (is) 2008-10-15
WO2003102012A3 (fr) 2004-04-22
DE60310714D1 (de) 2007-02-08
US20050222113A1 (en) 2005-10-06
IL165087A0 (en) 2005-12-18
IS7528A (is) 2004-11-15
CN1314701C (zh) 2007-05-09
AR040130A1 (es) 2005-03-16
DK1513861T3 (da) 2007-04-10

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