ZA200402055B - Autologous growth factor cocktail composition, method of production and use. - Google Patents
Autologous growth factor cocktail composition, method of production and use. Download PDFInfo
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- ZA200402055B ZA200402055B ZA200402055A ZA200402055A ZA200402055B ZA 200402055 B ZA200402055 B ZA 200402055B ZA 200402055 A ZA200402055 A ZA 200402055A ZA 200402055 A ZA200402055 A ZA 200402055A ZA 200402055 B ZA200402055 B ZA 200402055B
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- South Africa
- Prior art keywords
- growth factor
- chondrocytes
- growth factors
- composition
- growth
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- 238000001727 in vivo Methods 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
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- 239000007791 liquid phase Substances 0.000 description 1
- 238000011068 loading method Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 210000002901 mesenchymal stem cell Anatomy 0.000 description 1
- 108020004999 messenger RNA Proteins 0.000 description 1
- 230000000877 morphologic effect Effects 0.000 description 1
- 229920001220 nitrocellulos Polymers 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 239000011368 organic material Substances 0.000 description 1
- 230000000278 osteoconductive effect Effects 0.000 description 1
- 229920002866 paraformaldehyde Polymers 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 239000012071 phase Substances 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 238000007747 plating Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 238000012340 reverse transcriptase PCR Methods 0.000 description 1
- 210000000513 rotator cuff Anatomy 0.000 description 1
- 239000000565 sealant Substances 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 238000002415 sodium dodecyl sulfate polyacrylamide gel electrophoresis Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000007711 solidification Methods 0.000 description 1
- 230000008023 solidification Effects 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 210000005065 subchondral bone plate Anatomy 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 210000004876 tela submucosa Anatomy 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Materials For Medical Uses (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32445301P | 2001-09-24 | 2001-09-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200402055B true ZA200402055B (en) | 2005-06-22 |
Family
ID=23263651
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200402055A ZA200402055B (en) | 2001-09-24 | 2004-03-15 | Autologous growth factor cocktail composition, method of production and use. |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20030144197A1 (de) |
| EP (1) | EP1438067A4 (de) |
| JP (1) | JP2005521633A (de) |
| KR (1) | KR20040053137A (de) |
| CN (1) | CN1592635A (de) |
| BR (1) | BR0212757A (de) |
| CA (1) | CA2460780A1 (de) |
| HU (1) | HUP0501114A2 (de) |
| IL (1) | IL160883A0 (de) |
| MX (1) | MXPA04002716A (de) |
| NO (1) | NO20041212L (de) |
| PL (1) | PL371977A1 (de) |
| RU (1) | RU2004112543A (de) |
| WO (1) | WO2003026689A1 (de) |
| ZA (1) | ZA200402055B (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE220564T1 (de) | 1997-08-14 | 2002-08-15 | Sulzer Innotec Ag | Zusammensetzung und vorrichtung zur reparatur von knorpelgewebe in vivo bestehend aus nanokapseln mit osteoinduktiven und/oder chondroinduktiven faktoren |
| US7435260B2 (en) * | 1999-08-13 | 2008-10-14 | Ferree Bret A | Use of morphogenetic proteins to treat human disc disease |
| US6755863B2 (en) * | 1999-10-08 | 2004-06-29 | Bret A. Ferree | Rotator cuff repair using engineered tissues |
| EP1531855A4 (de) | 2002-01-10 | 2009-07-22 | Osteotrophin Llc | Behandlung von knochenerkrankungen mit skelettalen anabolika |
| US20040136968A1 (en) | 2002-09-27 | 2004-07-15 | Verigen Ag | Autologous cells on a support matrix for tissue repair |
| JP2005060307A (ja) * | 2003-08-12 | 2005-03-10 | Pirumu:Kk | 骨造成剤 |
| US8697139B2 (en) | 2004-09-21 | 2014-04-15 | Frank M. Phillips | Method of intervertebral disc treatment using articular chondrocyte cells |
| CA2641063C (en) * | 2006-03-23 | 2017-11-28 | The University Of Western Australia | Tenocyte cell culturing method |
| WO2008031196A1 (en) * | 2006-09-13 | 2008-03-20 | Enhance Skin Products, Inc. | Treatment of aged skin with autologous growth factors in a hyaluronic acid delivery system |
| WO2008128342A1 (en) * | 2007-04-18 | 2008-10-30 | Mcgill University | Composition for enhancing bone formation |
| US8513193B2 (en) | 2008-10-13 | 2013-08-20 | University Of Rochester | Protecting and repairing cartilage and musculoskeletal soft tissues |
| KR20110086045A (ko) * | 2008-10-24 | 2011-07-27 | 오스테오테크, 인코포레이티드 | 뼈 형성 촉진용 조성물 및 뼈 형성 촉진방법 |
| KR101288587B1 (ko) * | 2011-07-12 | 2013-08-22 | 휴먼바이오텍 주식회사 | 줄기세포로부터 분비된 성장 인자의 대량 분리 및 농축 방법 |
| US20140141047A1 (en) * | 2012-11-19 | 2014-05-22 | Wisconsin Alumni Research Foundation | Selection of platelet rich plasma components via mineral binding |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5158934A (en) * | 1989-09-01 | 1992-10-27 | Genentech, Inc. | Method of inducing bone growth using TGF-β |
| CA2071912C (en) * | 1990-11-30 | 2002-10-15 | Hanne Bentz | Use of a bone morphogenetic protein in synergistic combination with tgf-beta for bone repair |
| US6413511B1 (en) * | 1990-12-20 | 2002-07-02 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Cartilage alterations by administering to joints chondrocytes comprising a heterologous polynucleotide |
| ZA923086B (en) * | 1991-04-29 | 1993-10-28 | South African Medical Research | A delivery system for biologicaly active growth or morphogenetic factors and a method for preparing such delivery system |
| US5837258A (en) * | 1991-08-30 | 1998-11-17 | University Of South Florida | Induction of tissue, bone or cartilage formation using connective tissue growth factor |
| US5770209A (en) * | 1991-08-30 | 1998-06-23 | University Of South Florida | Acceleration of wound healing using connective tissue growth factor |
| JP3585180B2 (ja) * | 1993-05-11 | 2004-11-04 | 三菱化学株式会社 | 新規なヒトタンパク質およびそれをコードする遺伝子 |
| US5989269A (en) * | 1996-08-30 | 1999-11-23 | Vts Holdings L.L.C. | Method, instruments and kit for autologous transplantation |
| WO2002095399A2 (en) * | 2001-03-30 | 2002-11-28 | Verigen Ag | Method for certifying chondrocytes for use in cartilage regeneration |
-
2002
- 2002-09-24 IL IL16088302A patent/IL160883A0/xx unknown
- 2002-09-24 CN CNA028233093A patent/CN1592635A/zh active Pending
- 2002-09-24 EP EP02773559A patent/EP1438067A4/de not_active Withdrawn
- 2002-09-24 CA CA002460780A patent/CA2460780A1/en not_active Abandoned
- 2002-09-24 KR KR10-2004-7004248A patent/KR20040053137A/ko not_active Application Discontinuation
- 2002-09-24 PL PL02371977A patent/PL371977A1/xx not_active Application Discontinuation
- 2002-09-24 WO PCT/US2002/030343 patent/WO2003026689A1/en not_active Application Discontinuation
- 2002-09-24 HU HU0501114A patent/HUP0501114A2/hu unknown
- 2002-09-24 RU RU2004112543/15A patent/RU2004112543A/ru not_active Application Discontinuation
- 2002-09-24 JP JP2003530324A patent/JP2005521633A/ja active Pending
- 2002-09-24 BR BR0212757-1A patent/BR0212757A/pt not_active IP Right Cessation
- 2002-09-24 MX MXPA04002716A patent/MXPA04002716A/es not_active Application Discontinuation
- 2002-09-24 US US10/254,124 patent/US20030144197A1/en not_active Abandoned
-
2004
- 2004-03-15 ZA ZA200402055A patent/ZA200402055B/en unknown
- 2004-03-23 NO NO20041212A patent/NO20041212L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1592635A (zh) | 2005-03-09 |
| EP1438067A1 (de) | 2004-07-21 |
| WO2003026689A1 (en) | 2003-04-03 |
| IL160883A0 (en) | 2004-08-31 |
| NO20041212L (no) | 2004-05-10 |
| KR20040053137A (ko) | 2004-06-23 |
| WO2003026689A8 (en) | 2004-06-10 |
| JP2005521633A (ja) | 2005-07-21 |
| EP1438067A4 (de) | 2006-06-14 |
| CA2460780A1 (en) | 2003-04-03 |
| PL371977A1 (en) | 2005-07-11 |
| HUP0501114A2 (en) | 2007-11-28 |
| MXPA04002716A (es) | 2005-11-08 |
| BR0212757A (pt) | 2004-10-13 |
| US20030144197A1 (en) | 2003-07-31 |
| RU2004112543A (ru) | 2005-03-27 |
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