ZA200401725B - Substituted 5,6,6a,11b-tetrahydro-7-oxa-5-aza-benzo[c]-fluorene-6-carboxylic acid derivatives serving as NMDA antagonists. - Google Patents
Substituted 5,6,6a,11b-tetrahydro-7-oxa-5-aza-benzo[c]-fluorene-6-carboxylic acid derivatives serving as NMDA antagonists. Download PDFInfo
- Publication number
- ZA200401725B ZA200401725B ZA200401725A ZA200401725A ZA200401725B ZA 200401725 B ZA200401725 B ZA 200401725B ZA 200401725 A ZA200401725 A ZA 200401725A ZA 200401725 A ZA200401725 A ZA 200401725A ZA 200401725 B ZA200401725 B ZA 200401725B
- Authority
- ZA
- South Africa
- Prior art keywords
- polysubstituted
- unsubstituted
- mono
- benzo
- aza
- Prior art date
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- 239000005557 antagonist Substances 0.000 title description 7
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Classifications
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- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Diabetes (AREA)
- Addiction (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Psychology (AREA)
- Ophthalmology & Optometry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Dermatology (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10137487A DE10137487A1 (de) | 2001-08-03 | 2001-08-03 | Substituierte 5,6,6a,11b-Tetrahydro-7-oxa-6-aza- benzo[c]fluoren-6-carbonsäurederivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200401725B true ZA200401725B (en) | 2005-01-31 |
Family
ID=7693857
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200401725A ZA200401725B (en) | 2001-08-03 | 2004-03-02 | Substituted 5,6,6a,11b-tetrahydro-7-oxa-5-aza-benzo[c]-fluorene-6-carboxylic acid derivatives serving as NMDA antagonists. |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US7199130B2 (hu) |
| EP (1) | EP1412361B1 (hu) |
| JP (1) | JP2005500374A (hu) |
| KR (1) | KR20040020078A (hu) |
| CN (1) | CN1697836A (hu) |
| AT (1) | ATE402178T1 (hu) |
| BR (1) | BR0211734A (hu) |
| CA (1) | CA2456124A1 (hu) |
| CO (1) | CO5550438A2 (hu) |
| DE (2) | DE10137487A1 (hu) |
| EC (1) | ECSP044968A (hu) |
| ES (1) | ES2310211T3 (hu) |
| HU (1) | HUP0400800A3 (hu) |
| IL (1) | IL160160A0 (hu) |
| MX (1) | MXPA04000953A (hu) |
| NO (1) | NO20040471L (hu) |
| NZ (1) | NZ531372A (hu) |
| PL (1) | PL368073A1 (hu) |
| RU (1) | RU2004106533A (hu) |
| WO (1) | WO2003014124A1 (hu) |
| ZA (1) | ZA200401725B (hu) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10304950A1 (de) * | 2003-02-06 | 2004-08-19 | Grünenthal GmbH | Herstellung von Tetrahydrochinolinbenzofuranen |
| KR20050021629A (ko) * | 2003-08-25 | 2005-03-07 | 학교법인 이화학당 | 신규한 벤조플루오렌 디온계 화합물 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE147732T1 (de) * | 1989-03-08 | 1997-02-15 | Merck Sharp & Dohme | Tetrahydroquinolin-derivate, verwendbar bei neurodegenerativen krankheiten |
| DE19536809A1 (de) * | 1995-10-02 | 1997-04-03 | Basf Ag | Heterocyclisch substituierte Salicylsäurederivate |
| US5925527A (en) * | 1997-02-04 | 1999-07-20 | Trega Biosciences, Inc. | Tricyclic Tetrahydroquinoline derivatives and tricyclic tetrahydroquinoline combinatorial libraries |
| GB9706294D0 (en) * | 1997-03-26 | 1997-05-14 | Glaxo Wellcome Spa | Heterocyclic compound |
| MY125037A (en) * | 1998-06-10 | 2006-07-31 | Glaxo Wellcome Spa | 1,2,3,4 tetrahydroquinoline derivatives |
| DE10005302A1 (de) * | 2000-02-07 | 2002-01-17 | Gruenenthal Gmbh | Substituierte 1,2,3,4-Tetrahydrochinolin-2-carbonsäurederivate |
-
2001
- 2001-08-03 DE DE10137487A patent/DE10137487A1/de not_active Withdrawn
-
2002
- 2002-08-05 HU HU0400800A patent/HUP0400800A3/hu unknown
- 2002-08-05 IL IL16016002A patent/IL160160A0/xx unknown
- 2002-08-05 JP JP2003519073A patent/JP2005500374A/ja not_active Withdrawn
- 2002-08-05 RU RU2004106533/04A patent/RU2004106533A/ru not_active Application Discontinuation
- 2002-08-05 WO PCT/EP2002/008886 patent/WO2003014124A1/de active IP Right Grant
- 2002-08-05 ES ES02764838T patent/ES2310211T3/es not_active Expired - Lifetime
- 2002-08-05 DE DE50212538T patent/DE50212538D1/de not_active Expired - Lifetime
- 2002-08-05 KR KR10-2004-7001698A patent/KR20040020078A/ko not_active Application Discontinuation
- 2002-08-05 CA CA002456124A patent/CA2456124A1/en not_active Abandoned
- 2002-08-05 AT AT02764838T patent/ATE402178T1/de active
- 2002-08-05 NZ NZ531372A patent/NZ531372A/en unknown
- 2002-08-05 BR BR0211734-7A patent/BR0211734A/pt not_active IP Right Cessation
- 2002-08-05 MX MXPA04000953A patent/MXPA04000953A/es unknown
- 2002-08-05 PL PL02368073A patent/PL368073A1/xx not_active Application Discontinuation
- 2002-08-05 CN CNA028195124A patent/CN1697836A/zh active Pending
- 2002-08-05 EP EP02764838A patent/EP1412361B1/de not_active Expired - Lifetime
-
2004
- 2004-02-02 NO NO20040471A patent/NO20040471L/no not_active Application Discontinuation
- 2004-02-02 EC EC2004004968A patent/ECSP044968A/es unknown
- 2004-02-03 US US10/770,126 patent/US7199130B2/en not_active Expired - Fee Related
- 2004-02-03 CO CO04008285A patent/CO5550438A2/es not_active Application Discontinuation
- 2004-03-02 ZA ZA200401725A patent/ZA200401725B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BR0211734A (pt) | 2004-09-21 |
| KR20040020078A (ko) | 2004-03-06 |
| HUP0400800A2 (hu) | 2004-07-28 |
| CA2456124A1 (en) | 2003-02-20 |
| ECSP044968A (es) | 2004-03-23 |
| HUP0400800A3 (en) | 2007-09-28 |
| MXPA04000953A (es) | 2004-04-20 |
| NZ531372A (en) | 2005-03-24 |
| ES2310211T3 (es) | 2009-01-01 |
| PL368073A1 (en) | 2005-03-21 |
| EP1412361A1 (de) | 2004-04-28 |
| NO20040471L (no) | 2004-02-02 |
| DE10137487A1 (de) | 2003-03-27 |
| CO5550438A2 (es) | 2005-08-31 |
| JP2005500374A (ja) | 2005-01-06 |
| EP1412361B1 (de) | 2008-07-23 |
| DE50212538D1 (de) | 2008-09-04 |
| US7199130B2 (en) | 2007-04-03 |
| RU2004106533A (ru) | 2005-07-27 |
| WO2003014124A1 (de) | 2003-02-20 |
| IL160160A0 (en) | 2004-07-25 |
| ATE402178T1 (de) | 2008-08-15 |
| US20040248889A1 (en) | 2004-12-09 |
| CN1697836A (zh) | 2005-11-16 |
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