ZA200302507B - Preventives and remedies for complications of diabetes. - Google Patents
Preventives and remedies for complications of diabetes. Download PDFInfo
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- ZA200302507B ZA200302507B ZA200302507A ZA200302507A ZA200302507B ZA 200302507 B ZA200302507 B ZA 200302507B ZA 200302507 A ZA200302507 A ZA 200302507A ZA 200302507 A ZA200302507 A ZA 200302507A ZA 200302507 B ZA200302507 B ZA 200302507B
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- osteopontin
- diabetic
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- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 1
- 210000004509 vascular smooth muscle cell Anatomy 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/191—Carboxylic acids, e.g. valproic acid having two or more hydroxy groups, e.g. gluconic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/25—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids with polyoxyalkylated alcohols, e.g. esters of polyethylene glycol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000311960 | 2000-10-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200302507B true ZA200302507B (en) | 2004-03-31 |
Family
ID=18791637
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200302507A ZA200302507B (en) | 2000-10-12 | 2001-10-11 | Preventives and remedies for complications of diabetes. |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US20040087597A1 (no) |
| EP (1) | EP1325745B1 (no) |
| JP (1) | JPWO2002030425A1 (no) |
| KR (1) | KR100830018B1 (no) |
| CN (1) | CN1230173C (no) |
| AT (1) | ATE401886T1 (no) |
| AU (2) | AU2001294221B2 (no) |
| CA (1) | CA2424060A1 (no) |
| CZ (1) | CZ2003934A3 (no) |
| DE (1) | DE60135000D1 (no) |
| HK (1) | HK1060311A1 (no) |
| HU (1) | HUP0303353A3 (no) |
| IL (1) | IL155173A0 (no) |
| MX (1) | MXPA03003204A (no) |
| NO (1) | NO20031678L (no) |
| NZ (1) | NZ525150A (no) |
| PL (1) | PL361097A1 (no) |
| RU (1) | RU2003113328A (no) |
| SK (1) | SK4112003A3 (no) |
| WO (1) | WO2002030425A1 (no) |
| ZA (1) | ZA200302507B (no) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE511395T1 (de) * | 2001-04-19 | 2011-06-15 | Kowa Co | Mittel zur behandlung von glomerulopathie |
| EP1614429A4 (en) * | 2003-04-17 | 2007-05-02 | Kowa Co | LKLF / KLF2 GEN-EXPRESSIONSPROMOTER |
| EP1618893A4 (en) * | 2003-04-28 | 2009-08-12 | Sankyo Co | MEANS FOR INCREASING SUGAR CAPACITY |
| JP2005232151A (ja) * | 2003-04-28 | 2005-09-02 | Iichiro Shimomura | 糖取り込み能増強剤 |
| CA2524134C (en) | 2003-04-28 | 2017-07-04 | Sankyo Company Limited | Adiponectin production enhancer |
| ZA200509286B (en) * | 2003-05-23 | 2007-01-31 | Kowa Co | Carboxylic compound and medicine comprising the same |
| WO2006064825A1 (ja) * | 2004-12-14 | 2006-06-22 | Santen Pharmaceutical Co., Ltd. | ドライアイ治療剤 |
| EP1785133A1 (en) * | 2005-11-10 | 2007-05-16 | Laboratoires Fournier S.A. | Use of fenofibrate or a derivative thereof for preventing diabetic retinopathy |
| EP2626069A4 (en) * | 2010-10-06 | 2014-03-19 | Univ Tokyo | A MEDICINAL PRODUCT FOR THE PREVENTION AND TREATMENT OF A DERY LYMPH |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5612114B2 (no) * | 1974-06-07 | 1981-03-18 | ||
| US4346772A (en) * | 1978-01-03 | 1982-08-31 | Clifft Dale L | Power assisting device for a manually operating vehicle |
| US4231938A (en) * | 1979-06-15 | 1980-11-04 | Merck & Co., Inc. | Hypocholesteremic fermentation products and process of preparation |
| US4444784A (en) * | 1980-08-05 | 1984-04-24 | Merck & Co., Inc. | Antihypercholesterolemic compounds |
| US4739073A (en) * | 1983-11-04 | 1988-04-19 | Sandoz Pharmaceuticals Corp. | Intermediates in the synthesis of indole analogs of mevalonolactone and derivatives thereof |
| US4588715A (en) * | 1984-06-04 | 1986-05-13 | Sandoz, Inc. | Heptenoic acid derivatives |
| US4613610A (en) * | 1984-06-22 | 1986-09-23 | Sandoz Pharmaceuticals Corp. | Cholesterol biosynthesis inhibiting pyrazole analogs of mevalonolactone and its derivatives |
| US4804679A (en) * | 1984-07-24 | 1989-02-14 | Sandoz Pharm. Corp. | Erythro-(E)-7-(3'-C1-3alkyl-1'-(3",5"-dimethylphenyl)naphth-2'-yl)-3,5-dihydroxyhept-6-enoic acids and derivatives thereof |
| US5001255A (en) * | 1984-12-04 | 1991-03-19 | Sandoz Pharm. Corp. | Idene analogs of mevalonolactone and derivatives thereof |
| US4851427A (en) * | 1985-10-25 | 1989-07-25 | Sandoz Pharm. Corp. | Pyrrole analogs of mevalonolactone, derivatives thereof and pharmaceutical use |
| US4927851A (en) * | 1986-01-07 | 1990-05-22 | Sandoz Pharm. Corp. | Analogs of mevalonolactone and derivatives thereof |
| US4829081A (en) * | 1986-01-07 | 1989-05-09 | Sandoz Pharm. Corp. | Analogs of mevalonolactone and derivatives thereof |
| US4751235A (en) * | 1986-12-23 | 1988-06-14 | Sandoz Pharm. Corp. | Anti-atherosclerotic indolizine derivatives |
| US4939159A (en) * | 1986-09-10 | 1990-07-03 | Sandoz Pharm. Corp. | Azaindole derivatives useful as cholesterol biosynthesis inhibitors |
| JP2569746B2 (ja) * | 1987-08-20 | 1997-01-08 | 日産化学工業株式会社 | キノリン系メバロノラクトン類 |
| EP0308736A3 (en) * | 1987-09-12 | 1990-02-14 | Nissan Chemical Industries Ltd. | Pyrimidine type mevalonolactones |
| US4868185A (en) * | 1987-12-10 | 1989-09-19 | Warner-Lambert Company | 6-[[Substituted)pyrimidinyl)ethyl]- and ethenyl]tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis |
| US4822799A (en) * | 1988-01-27 | 1989-04-18 | Sandoz Pharm. Corp. | Pyrazolopyridine analogs of mevalonolactone and derivatives thereof useful for inhibiting cholesterol biosynthesis in mammals |
| AU628862B2 (en) * | 1988-10-03 | 1992-09-24 | Glaxo Group Limited | Substituted n-vinyl imidazole derivatives |
| FI94339C (fi) * | 1989-07-21 | 1995-08-25 | Warner Lambert Co | Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi |
| CA2052014A1 (en) * | 1990-10-19 | 1992-04-20 | Henry Y. Pan | Method for preventing diabetic complications employing a cholesterol lowering drug alone or in combination with an ace inhibitor |
| US5177080A (en) * | 1990-12-14 | 1993-01-05 | Bayer Aktiengesellschaft | Substituted pyridyl-dihydroxy-heptenoic acid and its salts |
| JP2648897B2 (ja) * | 1991-07-01 | 1997-09-03 | 塩野義製薬株式会社 | ピリミジン誘導体 |
| TW438587B (en) * | 1995-06-20 | 2001-06-07 | Takeda Chemical Industries Ltd | A pharmaceutical composition for prophylaxis and treatment of diabetes |
| RU2214402C2 (ru) * | 1998-07-23 | 2003-10-20 | Ниссан Кемикал Индастриз, Лтд. | Способ получения 3-((2-циклопропил-4-(4-фторфенил)-3-хинолил)проп-2-еналя и промежуточное соединение |
| GB0001662D0 (en) * | 1999-02-06 | 2000-03-15 | Zeneca Ltd | Pharmaceutical compositions |
| AU2866400A (en) * | 1999-03-08 | 2000-09-28 | Merck & Co., Inc. | Dihydroxy open-acid and salts of hmg-co-a reductase inhibitors |
| WO2001054694A1 (en) * | 2000-01-28 | 2001-08-02 | Bristol-Myers Squibb Company | Tetrahydropyrimidone inhibitors of fatty acid binding protein and method |
| US8186012B2 (en) * | 2004-06-03 | 2012-05-29 | The Wooster Brush Company | Pole grip with storage compartment |
-
2001
- 2001-10-11 SK SK411-2003A patent/SK4112003A3/sk not_active Application Discontinuation
- 2001-10-11 MX MXPA03003204A patent/MXPA03003204A/es unknown
- 2001-10-11 AU AU2001294221A patent/AU2001294221B2/en not_active Ceased
- 2001-10-11 WO PCT/JP2001/008921 patent/WO2002030425A1/ja active IP Right Grant
- 2001-10-11 EP EP01974780A patent/EP1325745B1/en not_active Expired - Lifetime
- 2001-10-11 IL IL15517301A patent/IL155173A0/xx unknown
- 2001-10-11 CZ CZ2003934A patent/CZ2003934A3/cs unknown
- 2001-10-11 PL PL01361097A patent/PL361097A1/xx not_active Application Discontinuation
- 2001-10-11 AU AU9422101A patent/AU9422101A/xx active Pending
- 2001-10-11 CA CA002424060A patent/CA2424060A1/en not_active Abandoned
- 2001-10-11 ZA ZA200302507A patent/ZA200302507B/en unknown
- 2001-10-11 US US10/381,635 patent/US20040087597A1/en not_active Abandoned
- 2001-10-11 DE DE60135000T patent/DE60135000D1/de not_active Expired - Lifetime
- 2001-10-11 KR KR1020037005082A patent/KR100830018B1/ko not_active IP Right Cessation
- 2001-10-11 RU RU2003113328/15A patent/RU2003113328A/ru not_active Application Discontinuation
- 2001-10-11 HU HU0303353A patent/HUP0303353A3/hu unknown
- 2001-10-11 AT AT01974780T patent/ATE401886T1/de not_active IP Right Cessation
- 2001-10-11 CN CNB018172393A patent/CN1230173C/zh not_active Expired - Fee Related
- 2001-10-11 NZ NZ525150A patent/NZ525150A/en not_active IP Right Cessation
- 2001-10-11 JP JP2002533866A patent/JPWO2002030425A1/ja active Pending
-
2003
- 2003-04-11 NO NO20031678A patent/NO20031678L/no unknown
-
2004
- 2004-05-14 HK HK04103418A patent/HK1060311A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CN1230173C (zh) | 2005-12-07 |
| MXPA03003204A (es) | 2004-12-03 |
| CN1469745A (zh) | 2004-01-21 |
| JPWO2002030425A1 (ja) | 2004-02-19 |
| HK1060311A1 (en) | 2004-08-06 |
| EP1325745A4 (en) | 2005-07-13 |
| CZ2003934A3 (cs) | 2003-11-12 |
| PL361097A1 (en) | 2004-09-20 |
| AU9422101A (en) | 2002-04-22 |
| NO20031678D0 (no) | 2003-04-11 |
| ATE401886T1 (de) | 2008-08-15 |
| NO20031678L (no) | 2003-04-11 |
| KR20030060905A (ko) | 2003-07-16 |
| RU2003113328A (ru) | 2004-09-10 |
| NZ525150A (en) | 2004-10-29 |
| HUP0303353A2 (hu) | 2004-01-28 |
| HUP0303353A3 (en) | 2004-10-28 |
| DE60135000D1 (de) | 2008-09-04 |
| EP1325745B1 (en) | 2008-07-23 |
| IL155173A0 (en) | 2003-10-31 |
| KR100830018B1 (ko) | 2008-05-15 |
| EP1325745A1 (en) | 2003-07-09 |
| SK4112003A3 (en) | 2004-01-08 |
| CA2424060A1 (en) | 2003-03-31 |
| WO2002030425A1 (fr) | 2002-04-18 |
| US20040087597A1 (en) | 2004-05-06 |
| AU2001294221B2 (en) | 2005-09-29 |
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