ZA200208840B - Disulfide derivatives useful for treating allergic diseases. - Google Patents
Disulfide derivatives useful for treating allergic diseases. Download PDFInfo
- Publication number
- ZA200208840B ZA200208840B ZA200208840A ZA200208840A ZA200208840B ZA 200208840 B ZA200208840 B ZA 200208840B ZA 200208840 A ZA200208840 A ZA 200208840A ZA 200208840 A ZA200208840 A ZA 200208840A ZA 200208840 B ZA200208840 B ZA 200208840B
- Authority
- ZA
- South Africa
- Prior art keywords
- alkyl
- substituted
- cycloalkyl
- alkenyl
- alkoxy
- Prior art date
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- 208000010110 spontaneous platelet aggregation Diseases 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 238000012353 t test Methods 0.000 description 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
- 229960000337 tetryzoline Drugs 0.000 description 1
- HNONEKILPDHFOL-UHFFFAOYSA-M tolonium chloride Chemical compound [Cl-].C1=C(C)C(N)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 HNONEKILPDHFOL-UHFFFAOYSA-M 0.000 description 1
- 238000011200 topical administration Methods 0.000 description 1
- 201000005539 vernal conjunctivitis Diseases 0.000 description 1
- 230000035899 viability Effects 0.000 description 1
- 239000008215 water for injection Substances 0.000 description 1
- 229960000833 xylometazoline Drugs 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
- C07C323/43—Y being a hetero atom
- C07C323/44—X or Y being nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Otolaryngology (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20582700P | 2000-05-19 | 2000-05-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200208840B true ZA200208840B (en) | 2003-12-02 |
Family
ID=22763799
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200208840A ZA200208840B (en) | 2000-05-19 | 2002-10-31 | Disulfide derivatives useful for treating allergic diseases. |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US6492552B2 (zh) |
| EP (1) | EP1282599B1 (zh) |
| JP (1) | JP2003534318A (zh) |
| KR (1) | KR20030007589A (zh) |
| CN (2) | CN1241912C (zh) |
| AR (1) | AR028566A1 (zh) |
| AT (1) | ATE330938T1 (zh) |
| AU (2) | AU2001255675B2 (zh) |
| BR (1) | BR0110943A (zh) |
| CA (1) | CA2407964A1 (zh) |
| CY (1) | CY1105164T1 (zh) |
| DE (1) | DE60120961T2 (zh) |
| DK (1) | DK1282599T3 (zh) |
| ES (1) | ES2261402T3 (zh) |
| HK (1) | HK1050185A1 (zh) |
| MX (1) | MXPA02011481A (zh) |
| PL (1) | PL365457A1 (zh) |
| PT (1) | PT1282599E (zh) |
| WO (1) | WO2001090060A1 (zh) |
| ZA (1) | ZA200208840B (zh) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1289945B1 (en) * | 2000-05-19 | 2004-08-04 | Alcon Inc. | Aniline disulfide derivatives for treating allergic diseases |
| AU2003259007A1 (en) | 2002-10-31 | 2004-05-25 | Amersham Biosciences Ab | Use of urea variants as affinity ligands |
| ZA200610350B (en) * | 2004-06-28 | 2008-12-31 | Alcon Inc | Topical formulations for treating allergic diseases |
| ATE421547T1 (de) * | 2004-12-22 | 2009-02-15 | California Inst Of Techn | Abbaubare polymere und herstellungsverfahren dafür |
| CN103974715A (zh) * | 2011-06-17 | 2014-08-06 | 哈洛齐梅公司 | 乙酰透明质酸降解酶的稳定制剂 |
| US9993529B2 (en) | 2011-06-17 | 2018-06-12 | Halozyme, Inc. | Stable formulations of a hyaluronan-degrading enzyme |
| FR3057264B1 (fr) * | 2016-10-12 | 2020-05-29 | Arkema France | Composes porteurs de groupes associatifs azotes |
| CN108586299B (zh) * | 2018-06-06 | 2020-06-16 | 北京化工大学 | 一种可引发、聚合及降低体积收缩的芳香二硫化合物的制备方法及用途 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1232787A (zh) | 1967-08-08 | 1971-05-19 | ||
| US3663616A (en) | 1969-10-13 | 1972-05-16 | Sherwin Williams Co | Bis(2-carbamylphenyl)disulfides |
| EP0006227B1 (en) | 1978-06-16 | 1984-12-27 | Kyowa Hakko Kogyo Co., Ltd | Antithrombotic pharmaceutical preparation containing 2,2'-dithiobis benzamide derivatives and new 2,2'-dithiobis benzamide derivatives |
| GB8520662D0 (en) | 1985-08-17 | 1985-09-25 | Wellcome Found | Tricyclic aromatic compounds |
| US4923892A (en) | 1985-08-17 | 1990-05-08 | Burroughs Wellcome Co. | Tricyclic aromatic compounds |
| JPS6310784A (ja) | 1986-03-03 | 1988-01-18 | Kyowa Hakko Kogyo Co Ltd | 抗アレルギー剤 |
| GB9020933D0 (en) | 1990-09-26 | 1990-11-07 | Ici Plc | Compound,preparation and use |
| US5859017A (en) | 1994-04-01 | 1999-01-12 | Cell Therapeutics, Inc. | Method for inhibiting mast cell and basophil activation |
| US5463122A (en) | 1994-08-05 | 1995-10-31 | Warner-Lambert Company | Arylthio compounds |
| US5734081A (en) | 1994-08-05 | 1998-03-31 | Warner-Lambert Company | Arylthio compounds |
| US6001555A (en) | 1994-09-23 | 1999-12-14 | The United States Of America As Represented By The Department Of Health And Human Services | Method for identifying and using compounds that inactivate HIV-1 and other retroviruses by attacking highly conserved zinc fingers in the viral nucleocapsid protein |
| JPH095926A (ja) | 1995-04-18 | 1997-01-10 | Fuji Photo Film Co Ltd | 熱現像感光材料 |
| US5641805A (en) | 1995-06-06 | 1997-06-24 | Alcon Laboratories, Inc. | Topical ophthalmic formulations for treating allergic eye diseases |
| US6225327B1 (en) | 1996-04-18 | 2001-05-01 | Alcon Laboratories, Inc. | Compounds which inhibit human conjunctival mast cell degranulation for treating ocular allergic-type complications |
| JP2894445B2 (ja) | 1997-02-12 | 1999-05-24 | 日本たばこ産業株式会社 | Ｃｅｔｐ活性阻害剤として有効な化合物 |
| JP3940201B2 (ja) | 1997-05-20 | 2007-07-04 | 大塚製薬株式会社 | ３，３’−ジチオジベンゾヒドロキサム酸 |
-
2001
- 2001-04-25 CN CNB200410073926XA patent/CN1241912C/zh not_active Expired - Fee Related
- 2001-04-25 CN CNB018094775A patent/CN1175807C/zh not_active Expired - Fee Related
- 2001-04-25 AU AU2001255675A patent/AU2001255675B2/en not_active Ceased
- 2001-04-25 CA CA002407964A patent/CA2407964A1/en not_active Abandoned
- 2001-04-25 BR BR0110943-0A patent/BR0110943A/pt not_active IP Right Cessation
- 2001-04-25 AU AU5567501A patent/AU5567501A/xx active Pending
- 2001-04-25 DE DE60120961T patent/DE60120961T2/de not_active Expired - Fee Related
- 2001-04-25 MX MXPA02011481A patent/MXPA02011481A/es active IP Right Grant
- 2001-04-25 JP JP2001586249A patent/JP2003534318A/ja not_active Ceased
- 2001-04-25 PT PT01928863T patent/PT1282599E/pt unknown
- 2001-04-25 ES ES01928863T patent/ES2261402T3/es not_active Expired - Lifetime
- 2001-04-25 KR KR1020027014929A patent/KR20030007589A/ko not_active Application Discontinuation
- 2001-04-25 AT AT01928863T patent/ATE330938T1/de not_active IP Right Cessation
- 2001-04-25 DK DK01928863T patent/DK1282599T3/da active
- 2001-04-25 PL PL01365457A patent/PL365457A1/xx not_active Application Discontinuation
- 2001-04-25 EP EP01928863A patent/EP1282599B1/en not_active Expired - Lifetime
- 2001-04-25 WO PCT/US2001/013331 patent/WO2001090060A1/en active IP Right Grant
- 2001-04-25 US US09/841,859 patent/US6492552B2/en not_active Expired - Fee Related
- 2001-05-15 AR ARP010102303A patent/AR028566A1/es not_active Application Discontinuation
-
2002
- 2002-05-22 US US10/153,716 patent/US6506802B2/en not_active Expired - Fee Related
- 2002-05-22 US US10/152,646 patent/US6500864B1/en not_active Expired - Fee Related
- 2002-10-31 ZA ZA200208840A patent/ZA200208840B/en unknown
-
2003
- 2003-04-02 HK HK03102377A patent/HK1050185A1/xx not_active IP Right Cessation
-
2006
- 2006-08-23 CY CY20061101174T patent/CY1105164T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR028566A1 (es) | 2003-05-14 |
| HK1050185A1 (en) | 2003-06-13 |
| AU5567501A (en) | 2001-12-03 |
| US20020193634A1 (en) | 2002-12-19 |
| US20020193633A1 (en) | 2002-12-19 |
| JP2003534318A (ja) | 2003-11-18 |
| BR0110943A (pt) | 2004-01-06 |
| US6506802B2 (en) | 2003-01-14 |
| EP1282599A1 (en) | 2003-02-12 |
| MXPA02011481A (es) | 2003-06-06 |
| ATE330938T1 (de) | 2006-07-15 |
| CA2407964A1 (en) | 2001-11-29 |
| WO2001090060A1 (en) | 2001-11-29 |
| US6492552B2 (en) | 2002-12-10 |
| CN1429209A (zh) | 2003-07-09 |
| PL365457A1 (en) | 2005-01-10 |
| DK1282599T3 (da) | 2006-07-31 |
| EP1282599B1 (en) | 2006-06-21 |
| ES2261402T3 (es) | 2006-11-16 |
| US20020058709A1 (en) | 2002-05-16 |
| AU2001255675B2 (en) | 2005-04-14 |
| CN1616422A (zh) | 2005-05-18 |
| US6500864B1 (en) | 2002-12-31 |
| CN1241912C (zh) | 2006-02-15 |
| CY1105164T1 (el) | 2010-03-03 |
| PT1282599E (pt) | 2006-08-31 |
| DE60120961D1 (de) | 2006-08-03 |
| KR20030007589A (ko) | 2003-01-23 |
| DE60120961T2 (de) | 2006-11-16 |
| CN1175807C (zh) | 2004-11-17 |
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