ZA200204193B

ZA200204193B - Fast dissolving composition with prolonged sweet taste.

Fast dissolving composition with prolonged sweet taste. Download PDF

Info

Publication number: ZA200204193B
Authority: ZA; South Africa
Prior art keywords: dosage form; sugar; weight; amount; sweetner
Prior art date: 1999-11-30

Application number

ZA200204193A

Other languages

English (en)

Inventor

Amarjit Singh

Rajesh Jain

Original Assignee

Panacea Biotec Ltd

Priority date

1999-11-30

Filing date

2002-05-27

Publication date

2003-05-27

2002-05-27 Application filed by Panacea Biotec Ltd filed Critical Panacea Biotec Ltd

2003-05-27 Publication of ZA200204193B publication Critical patent/ZA200204193B/en

Links

239000000203 mixture Substances 0.000 title claims description 11
230000002035 prolonged effect Effects 0.000 title claims description 11
235000019605 sweet taste sensations Nutrition 0.000 title claims description 11
235000000346 sugar Nutrition 0.000 claims description 24
239000002552 dosage form Substances 0.000 claims description 14
238000000034 method Methods 0.000 claims description 13
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 11
239000007909 solid dosage form Substances 0.000 claims description 10
239000008194 pharmaceutical composition Substances 0.000 claims description 7
229940079593 drug Drugs 0.000 claims description 6
239000003814 drug Substances 0.000 claims description 6
230000003232 mucoadhesive effect Effects 0.000 claims description 6
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 5
238000002360 preparation method Methods 0.000 claims description 5
239000011734 sodium Substances 0.000 claims description 5
229910052708 sodium Inorganic materials 0.000 claims description 5
FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 4
FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical group OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims description 4
229930195725 Mannitol Natural products 0.000 claims description 4
239000013543 active substance Substances 0.000 claims description 4
239000004615 ingredient Substances 0.000 claims description 4
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239000000600 sorbitol Substances 0.000 claims description 4
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WBZFUFAFFUEMEI-UHFFFAOYSA-M Acesulfame k Chemical compound [K+].CC1=CC(=O)[N-]S(=O)(=O)O1 WBZFUFAFFUEMEI-UHFFFAOYSA-M 0.000 claims description 3
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FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 3
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IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 claims description 3
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HCAJEUSONLESMK-UHFFFAOYSA-N cyclohexylsulfamic acid Chemical class OS(=O)(=O)NC1CCCCC1 HCAJEUSONLESMK-UHFFFAOYSA-N 0.000 claims description 3
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