ZA200201969B - Oral recombinant Lactobacilli vaccines. - Google Patents
Oral recombinant Lactobacilli vaccines. Download PDFInfo
- Publication number
- ZA200201969B ZA200201969B ZA200201969A ZA200201969A ZA200201969B ZA 200201969 B ZA200201969 B ZA 200201969B ZA 200201969 A ZA200201969 A ZA 200201969A ZA 200201969 A ZA200201969 A ZA 200201969A ZA 200201969 B ZA200201969 B ZA 200201969B
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- ZA
- South Africa
- Prior art keywords
- vaccine
- plantarum
- antigen
- lactobacillus
- bacterium
- Prior art date
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- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P31/10—Antimycotics
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- A61P31/12—Antivirals
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/746—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for lactic acid bacteria (Streptococcus; Lactococcus; Lactobacillus; Pediococcus; Enterococcus; Leuconostoc; Propionibacterium; Bifidobacterium; Sporolactobacillus)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/542—Mucosal route oral/gastrointestinal
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
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- Immunology (AREA)
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- Communicable Diseases (AREA)
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- General Engineering & Computer Science (AREA)
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- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Pulmonology (AREA)
- Plant Pathology (AREA)
- Virology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99203056A EP1084709A1 (fr) | 1999-09-17 | 1999-09-17 | Vaccin oral contenant des Lactobacilli recombinés |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200201969B true ZA200201969B (en) | 2003-08-27 |
Family
ID=8240652
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200201969A ZA200201969B (en) | 1999-09-17 | 2002-03-08 | Oral recombinant Lactobacilli vaccines. |
Country Status (10)
Country | Link |
---|---|
EP (2) | EP1084709A1 (fr) |
JP (1) | JP2003509469A (fr) |
CN (1) | CN1387442A (fr) |
AP (1) | AP2002002445A0 (fr) |
AU (1) | AU7433700A (fr) |
CA (1) | CA2383433A1 (fr) |
IL (1) | IL148713A0 (fr) |
OA (1) | OA12023A (fr) |
WO (1) | WO2001021200A1 (fr) |
ZA (1) | ZA200201969B (fr) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK1739178T3 (da) * | 1999-07-05 | 2010-11-22 | Actogenix Nv | Levering af trekløverpeptider |
US7060687B2 (en) | 2001-02-07 | 2006-06-13 | Genmont Biotechnology Co. | Live vaccines for allergy treatment |
JP4059648B2 (ja) * | 2001-08-28 | 2008-03-12 | 独立行政法人科学技術振興機構 | 経口用サイトカイン誘導剤 |
GB0124580D0 (en) * | 2001-10-12 | 2001-12-05 | Univ Reading | New composition |
EP1319410A1 (fr) * | 2001-12-11 | 2003-06-18 | Société des Produits Nestlé S.A. | Utilisation de microorganismes pour l'administration ciblée de substances dans des parties spécifiques de l'intestin |
US20040043003A1 (en) * | 2002-01-31 | 2004-03-04 | Wei Chen | Clinical grade vectors based on natural microflora for use in delivering therapeutic compositions |
EP1523559A1 (fr) * | 2002-06-18 | 2005-04-20 | Universite Catholique De Louvain | Mutants de paroi cellulaire pour la delivrance de composes biologiquement actifs |
DE602004005029T2 (de) * | 2003-05-22 | 2007-11-08 | Synbiotics Ab | Probiotische zusammensetzung mit mindestens zwei milchsäurebakterienstämmen, die zur kolonisierung des magen-darm-trakts fähig sind und in kombination damit die eigenschaften, im darm zu überleben, an den darm zu binden, gegen infektion zu schützen und ballaststoffe zu fermentieren, aufweisen |
EP1680508B1 (fr) * | 2003-10-28 | 2011-03-30 | Friesland Brands B.V. | Production et/ou administration intestinale specifique de site de substances actives |
EP1768688A4 (fr) * | 2004-07-02 | 2009-09-30 | Raymond J Dattwyler | Vaccin oral permettant de lutter contre des infections a borrelia |
EP1723965A1 (fr) * | 2005-05-18 | 2006-11-22 | Stallergenes Sa | Compositions pour l'induction de tolerance immunologique specifique à des antigènes à travers de la immunization orale |
WO2006126682A1 (fr) * | 2005-05-27 | 2006-11-30 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Vaccin pour la prévention / le traitement de la maladie d'alzheimer |
US8420376B2 (en) * | 2005-10-06 | 2013-04-16 | Probi Ab | Use of Lactobacillus for treatment of virus infections |
US8802419B2 (en) | 2006-03-02 | 2014-08-12 | University Of Massachusetts | Modified pathogens for use as vaccines |
JP5791009B2 (ja) * | 2008-12-22 | 2015-10-07 | アサヒグループホールディングス株式会社 | 乳酸菌およびそれらを用いた飲食物又は化粧品 |
CN103732248B (zh) * | 2011-04-06 | 2018-08-28 | 拜欧瓦克西姆有限公司 | 用于预防和/或治疗人中的hiv疾病的药物组合物 |
BR112013025481B8 (pt) | 2011-04-06 | 2022-11-22 | Univ Paris Descartes | Composições farmacêuticas, uso destas e kits para prevenir e/ou tratar uma doença por hiv em humanos |
CN102580118B (zh) * | 2012-02-24 | 2014-03-12 | 重庆大学 | 志贺样毒素Stx1B口服疫苗的制备方法及其产品 |
WO2014047625A1 (fr) * | 2012-09-24 | 2014-03-27 | Montana State University | Lactococcus lactis recombinant exprimant l'antigène 1 du facteur de colonisation d'escherichia coli (cfa/i) de type pilus et procédés d'utilisation correspondants |
KR102143856B1 (ko) * | 2013-06-11 | 2020-08-12 | 하우스 웰니스 푸드 코퍼레이션 | 대식세포에 물질을 송달하는 담체 |
SG11202009631WA (en) | 2018-03-31 | 2020-10-29 | Pebble Labs Usa Inc | Systems, methods and composition of using rnase iii mutants to produce srna to control host pathogen infection |
CA3198308A1 (fr) * | 2020-11-10 | 2022-05-19 | Dharanesh Mahimapura GANGAIAH | Compositions probiotiques immunogenes et procedes d'utilisation, y compris a des fins de vaccination |
GB202019767D0 (en) | 2020-12-15 | 2021-01-27 | Chain Biotechnology Ltd | Compostitions and methods |
CN113308396B (zh) * | 2021-05-18 | 2023-03-21 | 上海市公共卫生临床中心 | 一种植物乳杆菌及在制备新冠疫苗免疫增强剂中的应用 |
CN113304254A (zh) * | 2021-06-07 | 2021-08-27 | 吉林大学 | 一种微小隐孢子虫Cp15重组侵入型乳酸菌活载体疫苗 |
CN114561313B (zh) * | 2021-08-26 | 2022-09-13 | 佛山市孛特碧欧微生物科技有限公司 | 格氏乳杆菌及其应用 |
GB202209115D0 (en) | 2022-06-21 | 2022-08-10 | Chain Biotechnology Ltd | Compositions and methods |
DE102022119024A1 (de) * | 2022-07-28 | 2024-02-08 | INM - Leibniz-Institut für Neue Materialien gemeinnützige Gesellschaft mit beschränkter Haftung | Neuartige genetische Werkzeuge |
CN117586935B (zh) * | 2023-12-01 | 2024-05-10 | 华中农业大学 | 用于产肠毒素大肠杆菌k99菌毛型的乳酸乳球菌载体口服疫苗及应用 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL8700890A (nl) * | 1987-04-15 | 1988-11-01 | Tno | Transformatie van lactobacillus, daarbij bruikbare recombinante plasmiden, getransformeerde lactobacillus species en gebruik daarvan. |
GB9718616D0 (en) * | 1997-09-02 | 1997-11-05 | Queen Mary & Westfield College | Oral vaccine |
-
1999
- 1999-09-17 EP EP99203056A patent/EP1084709A1/fr not_active Withdrawn
-
2000
- 2000-09-18 EP EP00962689A patent/EP1212083A1/fr not_active Withdrawn
- 2000-09-18 WO PCT/GB2000/003575 patent/WO2001021200A1/fr not_active Application Discontinuation
- 2000-09-18 CA CA002383433A patent/CA2383433A1/fr not_active Abandoned
- 2000-09-18 AU AU74337/00A patent/AU7433700A/en not_active Abandoned
- 2000-09-18 JP JP2001524624A patent/JP2003509469A/ja active Pending
- 2000-09-18 CN CN00815334A patent/CN1387442A/zh active Pending
- 2000-09-18 OA OA1200200076A patent/OA12023A/en unknown
- 2000-09-18 AP APAP/P/2002/002445A patent/AP2002002445A0/en unknown
- 2000-09-18 IL IL14871300A patent/IL148713A0/xx unknown
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2002
- 2002-03-08 ZA ZA200201969A patent/ZA200201969B/en unknown
Also Published As
Publication number | Publication date |
---|---|
OA12023A (en) | 2006-04-19 |
AP2002002445A0 (en) | 2002-03-31 |
IL148713A0 (en) | 2002-09-12 |
JP2003509469A (ja) | 2003-03-11 |
EP1212083A1 (fr) | 2002-06-12 |
CA2383433A1 (fr) | 2001-03-29 |
CN1387442A (zh) | 2002-12-25 |
AU7433700A (en) | 2001-04-24 |
EP1084709A1 (fr) | 2001-03-21 |
WO2001021200A1 (fr) | 2001-03-29 |
EP1084709A9 (fr) | 2001-05-16 |
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