ZA200100607B - Methods of treating diabetic cardiomyopathy using glycogen phosphorylase inhibitors. - Google Patents
Methods of treating diabetic cardiomyopathy using glycogen phosphorylase inhibitors.Info
- Publication number
- ZA200100607B ZA200100607B ZA200100607A ZA200100607A ZA200100607B ZA 200100607 B ZA200100607 B ZA 200100607B ZA 200100607 A ZA200100607 A ZA 200100607A ZA 200100607 A ZA200100607 A ZA 200100607A ZA 200100607 B ZA200100607 B ZA 200100607B
- Authority
- ZA
- South Africa
- Prior art keywords
- methods
- glycogen phosphorylase
- treating diabetic
- phosphorylase inhibitors
- diabetic cardiomyopathy
- Prior art date
Links
- 208000032781 Diabetic cardiomyopathy Diseases 0.000 title 1
- 102000007390 Glycogen Phosphorylase Human genes 0.000 title 1
- 108010046163 Glycogen Phosphorylase Proteins 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
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- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
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- A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Pulmonology (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17777000P | 2000-01-24 | 2000-01-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200100607B true ZA200100607B (en) | 2002-07-22 |
Family
ID=22649922
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200100607A ZA200100607B (en) | 2000-01-24 | 2001-01-22 | Methods of treating diabetic cardiomyopathy using glycogen phosphorylase inhibitors. |
Country Status (12)
Country | Link |
---|---|
US (1) | US6867184B2 (xx) |
EP (1) | EP1125580A3 (xx) |
JP (1) | JP2001206856A (xx) |
KR (1) | KR20010083148A (xx) |
AU (1) | AU1639901A (xx) |
CA (1) | CA2331847A1 (xx) |
CO (1) | CO5271699A1 (xx) |
HU (1) | HUP0100321A3 (xx) |
IL (1) | IL140904A0 (xx) |
NZ (1) | NZ509481A (xx) |
PE (1) | PE20011053A1 (xx) |
ZA (1) | ZA200100607B (xx) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0021831D0 (en) * | 2000-09-06 | 2000-10-18 | Astrazeneca Ab | Chemical compounds |
AU775663B2 (en) * | 2000-10-20 | 2004-08-12 | Amylin Pharmaceuticals, Inc. | Treatment of hibernating myocardium and diabetic cardiomyopathy with a GLP-1 peptide |
CA2465382A1 (en) * | 2001-10-29 | 2003-05-08 | Japan Tobacco Inc. | Indole compound and medicinal use thereof |
GB0205175D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
GB0205162D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
GB0205165D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
GB0205170D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
GB0205176D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
GB0205166D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
JPWO2003080583A1 (ja) * | 2002-03-27 | 2005-07-21 | 三菱ウェルファーマ株式会社 | 心筋症の予防及び/又は治療のための医薬 |
US6960610B2 (en) | 2002-10-28 | 2005-11-01 | Novo Nordick, A/S | Use of glycogen phosphorylase inhibitors for treatment of cardiovascular diseases |
US7790681B2 (en) * | 2002-12-17 | 2010-09-07 | Amylin Pharmaceuticals, Inc. | Treatment of cardiac arrhythmias with GLP-1 receptor ligands |
US20040209803A1 (en) * | 2002-12-19 | 2004-10-21 | Alain Baron | Compositions for the treatment and prevention of nephropathy |
GB0309154D0 (en) * | 2003-01-14 | 2003-05-28 | Aventis Pharma Inc | Use of insulin glargine to reduce or prevent cardiovascular events in patients being treated for dysglycemia |
CA2515368A1 (en) * | 2003-02-13 | 2004-08-26 | Luciano Rossetti | Regulation of food intake and glucose production by modulation of long-chain fatty acyl-coa levels in the hypothalamus |
WO2006041922A2 (en) * | 2004-10-08 | 2006-04-20 | Dara Biosciences, Inc. | Agents and methods for administration to the central nervous system |
US7214704B2 (en) * | 2004-11-15 | 2007-05-08 | Bristol-Myers Squibb Company | 2-Amino-1-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors |
WO2006055462A1 (en) | 2004-11-15 | 2006-05-26 | Bristol-Myers Squibb Company | 2-amino-4-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors |
WO2006055435A1 (en) * | 2004-11-15 | 2006-05-26 | Bristol-Myers Squibb Company | 2-aminonaphthalene derivatives and related glycogen phosphorylase inhibitors |
US7365061B2 (en) * | 2004-11-15 | 2008-04-29 | Bristol-Myers Squibb Company | 2-Amino-3-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors |
US20090012067A1 (en) * | 2005-02-14 | 2009-01-08 | Luciano Rossetti | Modulation of Hypothalamic Atp-Sensitive Potassium Channels |
PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
SG174080A1 (en) * | 2006-09-13 | 2011-09-29 | Sanofi Aventis | Isoserine derivatives for use as coagulation factor ixa inhibitors |
KR101481041B1 (ko) * | 2007-11-30 | 2015-01-12 | (주)아모레퍼시픽 | 글루코오스-6-인산 탈수소효소의 활성 억제제 및 이를포함하는 지방세포 분화 억제용 조성물 |
CN104837503B (zh) * | 2012-08-21 | 2018-11-09 | 阿德利克斯公司 | 在治疗与液体潴留或盐分过载相关的疾病和胃肠道疾病中用于抑制nhe-介导的反向转运的化合物和方法 |
WO2017217128A1 (ja) * | 2016-06-16 | 2017-12-21 | 学校法人藤田学園 | 魚アレルギーの抗原 |
MX2020006198A (es) | 2017-12-15 | 2020-11-24 | Medizinische Hochschule Hannover | Compuesto mejorado para tratamiento de insuficiencia cardiaca. |
CN113304149A (zh) * | 2021-06-23 | 2021-08-27 | 广州医科大学 | 一种化合物在制备治疗2型糖尿病心肌病的药物中的应用 |
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DE3629545A1 (de) | 1986-08-30 | 1988-03-10 | Bayer Ag | Dihydropyridinverbindungen, verfahren zu ihrer herstellung und ihre verwendung |
ATE243196T1 (de) | 1994-03-09 | 2003-07-15 | Novo Nordisk As | Piperidine und pyrrolidine |
CA2223625C (en) * | 1995-06-06 | 2003-06-03 | Pfizer Inc. | Substituted n-(indole-2-carbonyl-) amides and derivatives as glycogen phosphorylase inhibitors |
US6107329A (en) | 1995-06-06 | 2000-08-22 | Pfizer, Inc. | Substituted n-(indole-2-carbonyl)-glycinamides and derivatives as glycogen phosphorylase inhibitors |
EP0858335B1 (en) | 1995-09-08 | 2003-03-12 | Novo Nordisk A/S | 2-alkylpyrrolidines |
AU2090897A (en) | 1996-02-29 | 1997-09-16 | Mikael Bols | Hydroxyhexahydropyridazines |
US5952322A (en) | 1996-12-05 | 1999-09-14 | Pfizer Inc. | Method of reducing tissue damage associated with non-cardiac ischemia using glycogen phosphorylase inhibitors |
ZA981920B (en) | 1997-03-07 | 1998-09-07 | Novo Nordisk As | Novel heterocyclic compounds |
IL124236A (en) | 1997-05-05 | 2003-01-12 | Pfizer | Pharmaceutical composition for treating or reversing diabetic cardiomyopathy comprising aldose reductase inhibitor |
IL132170A0 (en) | 1997-05-06 | 2001-03-19 | Novo Nordisk As | Novel heterocyclic compounds |
UA57811C2 (uk) | 1997-11-21 | 2003-07-15 | Пфайзер Продактс Інк. | Фармацевтична композиція, що містить інгібітор альдозоредуктази та інгібітор глікогенфосфорилази (варіанти), комплект, який її включає, та способи лікування ссавців зі станом інсулінорезистентності |
US5998463A (en) | 1998-02-27 | 1999-12-07 | Pfizer Inc | Glycogen phosphorylase inhibitors |
EP0978279A1 (en) * | 1998-08-07 | 2000-02-09 | Pfizer Products Inc. | Inhibitors of human glycogen phosphorylase |
PT1041068E (pt) * | 1999-04-01 | 2004-07-30 | Pfizer Prod Inc | Compostos para o tratamento e prevencao de complicacoes diabeticas |
EP1088824B1 (en) * | 1999-09-30 | 2004-01-07 | Pfizer Products Inc. | Bicyclic pyrrolyl amides as glycogen phosphorylase inhibitors |
GT200100039A (es) | 2000-03-16 | 2001-12-31 | Pfizer | Inhibidor de la glucogeno fosforilasa. |
US20010053778A1 (en) | 2000-03-16 | 2001-12-20 | Hoover Dennis J. | Pharmaceutical compositions of glycogen phosphorylase inhibitors |
US6277877B1 (en) * | 2000-08-15 | 2001-08-21 | Pfizer, Inc. | Substituted n-(indole-2-carbonyl)glycinamides and derivates as glycogen phosphorylase inhibitors |
GB0021831D0 (en) * | 2000-09-06 | 2000-10-18 | Astrazeneca Ab | Chemical compounds |
CA2674178C (en) | 2006-12-29 | 2015-11-10 | Tibotec Pharmaceuticals Ltd. | Hiv inhibiting 6-substituted pyrimidines |
-
2000
- 2000-12-27 CO CO00097924A patent/CO5271699A1/es not_active Application Discontinuation
-
2001
- 2001-01-15 IL IL14090401A patent/IL140904A0/xx unknown
- 2001-01-19 NZ NZ509481A patent/NZ509481A/en unknown
- 2001-01-22 CA CA002331847A patent/CA2331847A1/en not_active Abandoned
- 2001-01-22 ZA ZA200100607A patent/ZA200100607B/xx unknown
- 2001-01-23 EP EP01300575A patent/EP1125580A3/en not_active Withdrawn
- 2001-01-23 PE PE2001000073A patent/PE20011053A1/es not_active Application Discontinuation
- 2001-01-23 US US09/767,633 patent/US6867184B2/en not_active Expired - Fee Related
- 2001-01-23 JP JP2001014036A patent/JP2001206856A/ja active Pending
- 2001-01-23 AU AU16399/01A patent/AU1639901A/en not_active Abandoned
- 2001-01-23 HU HU0100321A patent/HUP0100321A3/hu unknown
- 2001-01-26 KR KR1020010003820A patent/KR20010083148A/ko active Search and Examination
Also Published As
Publication number | Publication date |
---|---|
EP1125580A2 (en) | 2001-08-22 |
NZ509481A (en) | 2005-02-25 |
CA2331847A1 (en) | 2001-07-24 |
HUP0100321A3 (en) | 2004-03-01 |
EP1125580A3 (en) | 2002-11-27 |
PE20011053A1 (es) | 2001-10-17 |
IL140904A0 (en) | 2002-02-10 |
CO5271699A1 (es) | 2003-04-30 |
HUP0100321A2 (en) | 2002-10-28 |
KR20010083148A (ko) | 2001-08-31 |
HU0100321D0 (en) | 2001-03-28 |
JP2001206856A (ja) | 2001-07-31 |
US20010046958A1 (en) | 2001-11-29 |
AU1639901A (en) | 2001-07-26 |
US6867184B2 (en) | 2005-03-15 |
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