ZA200006761B - Novel 2-alkyl substituted imidazole compounds. - Google Patents
Novel 2-alkyl substituted imidazole compounds. Download PDFInfo
- Publication number
- ZA200006761B ZA200006761B ZA200006761A ZA200006761A ZA200006761B ZA 200006761 B ZA200006761 B ZA 200006761B ZA 200006761 A ZA200006761 A ZA 200006761A ZA 200006761 A ZA200006761 A ZA 200006761A ZA 200006761 B ZA200006761 B ZA 200006761B
- Authority
- ZA
- South Africa
- Prior art keywords
- alkyl
- optionally substituted
- compound according
- aryl
- disease
- Prior art date
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- C07D—HETEROCYCLIC COMPOUNDS
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CA (1) | CA2332402A1 (ja) |
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AU7966198A (en) | 1997-06-13 | 1998-12-30 | Smithkline Beecham Corporation | Novel pyrazole and pyrazoline substituted compounds |
US6610695B1 (en) | 1997-06-19 | 2003-08-26 | Smithkline Beecham Corporation | Aryloxy substituted pyrimidine imidazole compounds |
US6562832B1 (en) | 1997-07-02 | 2003-05-13 | Smithkline Beecham Corporation | Substituted imidazole compounds |
US7301021B2 (en) | 1997-07-02 | 2007-11-27 | Smithkline Beecham Corporation | Substituted imidazole compounds |
US6489325B1 (en) | 1998-07-01 | 2002-12-03 | Smithkline Beecham Corporation | Substituted imidazole compounds |
EP1041989A4 (en) | 1997-10-08 | 2002-11-20 | Smithkline Beecham Corp | NEW SUBSTITUTED CYCLOALCENYL COMPOUNDS |
CA2341370A1 (en) | 1998-08-20 | 2000-03-02 | Smithkline Beecham Corporation | Novel substituted triazole compounds |
MXPA02005106A (es) | 1999-11-22 | 2002-11-07 | Smithkline Beecham Plc | Compuestos novedosos. |
DE60015599T2 (de) | 1999-11-23 | 2005-11-03 | Smithkline Beecham Corp. | 3,4-DIHYDRO-(1H)CHINAZOLIN-2-ON-VERBINDUNGEN ALS CSBP/p38-KINASE-INHIBITOREN |
WO2001066539A1 (en) | 2000-03-06 | 2001-09-13 | Smithkline Beecham P.L.C. | Imidazol derivatives as raf kinase inhibitors |
GB0005357D0 (en) | 2000-03-06 | 2000-04-26 | Smithkline Beecham Plc | Compounds |
JP4217480B2 (ja) * | 2000-11-20 | 2009-02-04 | スミスクライン・ビーチャム・コーポレイション | 新規化合物 |
GB0112348D0 (en) * | 2001-05-19 | 2001-07-11 | Smithkline Beecham Plc | Compounds |
EP1432703A1 (en) * | 2001-09-05 | 2004-06-30 | Smithkline Beecham Plc | Heterocycle-carboxamide derivatives as raf kinase inhibitors |
TWI329105B (en) | 2002-02-01 | 2010-08-21 | Rigel Pharmaceuticals Inc | 2,4-pyrimidinediamine compounds and their uses |
AU2003245989A1 (en) | 2002-07-09 | 2004-01-23 | Boehringer Ingelheim Pharma Gmbh And Co. Kg | Pharmaceutical compositions of anticholinergics and p38 kinase inhibitors in the treatment of respiratory diseases |
MXPA05001096A (es) | 2002-07-29 | 2005-11-23 | Rigel Pharmaceuticals Inc | Metodos para tratamiento o prevencion de enfermedades autoinmunes con compuestos de 2,4-diamino-pirimidina. |
WO2005016241A2 (en) | 2003-05-16 | 2005-02-24 | Intermune, Inc. | Synthetic chemokine receptor ligands and methods of use thereof |
US8178671B2 (en) | 2003-07-30 | 2012-05-15 | Rigel Pharmaceuticals, Inc. | Methods of treating or preventing autoimmune diseases with 2, 4-pyrimidinediamine compounds |
PL1680137T3 (pl) | 2003-10-14 | 2013-04-30 | F Hoffmann La Roche Ltd | Makrocykliczny kwas karboksylowy i związek acylosulfonamidowy jako inhibitor replikacji HCV |
US7407973B2 (en) * | 2003-10-24 | 2008-08-05 | Intermune, Inc. | Use of pirfenidone in therapeutic regimens |
US20060035893A1 (en) | 2004-08-07 | 2006-02-16 | Boehringer Ingelheim International Gmbh | Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders |
US7597884B2 (en) | 2004-08-09 | 2009-10-06 | Alios Biopharma, Inc. | Hyperglycosylated polypeptide variants and methods of use |
EP1789074A4 (en) * | 2004-08-09 | 2009-08-12 | Alios Biopharma Inc | PROTEASE-RESISTANT HYPERGLYCOSYL SYNTHETIC POLYPEPTIDE VARIANTS, ORAL FORMULATIONS AND METHODS OF USING THE SAME |
WO2006068770A1 (en) | 2004-11-24 | 2006-06-29 | Rigel Pharmaceuticals, Inc. | Spiro-2, 4-pyrimidinediamine compounds and their uses |
PE20060777A1 (es) | 2004-12-24 | 2006-10-06 | Boehringer Ingelheim Int | Derivados de indolinona para el tratamiento o la prevencion de enfermedades fibroticas |
TWI387592B (zh) * | 2005-08-30 | 2013-03-01 | Novartis Ag | 經取代之苯并咪唑及其作為與腫瘤形成相關激酶之抑制劑之方法 |
EP1992344A1 (en) | 2007-05-18 | 2008-11-19 | Institut Curie | P38 alpha as a therapeutic target in pathologies linked to FGFR3 mutation |
ES2779748T3 (es) | 2012-08-23 | 2020-08-19 | Janssen Biopharma Inc | Compuestos para el tratamiento de infecciones víricas por paramixovirus |
JP6485817B2 (ja) * | 2013-08-21 | 2019-03-20 | ヤンセン バイオファーマ インク. | 抗ウイルス化合物 |
MA41614A (fr) | 2015-02-25 | 2018-01-02 | Alios Biopharma Inc | Composés antiviraux |
US10342786B2 (en) | 2017-10-05 | 2019-07-09 | Fulcrum Therapeutics, Inc. | P38 kinase inhibitors reduce DUX4 and downstream gene expression for the treatment of FSHD |
HRP20221196T1 (hr) | 2017-10-05 | 2022-12-09 | Fulcrum Therapeutics, Inc. | Inhibitori p38 kinaze smanjuju ekspresiju dux4 i nizvodnih gena u cilju liječenja fshd |
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-
1999
- 1999-05-20 KR KR1020007013121A patent/KR20010025087A/ko not_active Application Discontinuation
- 1999-05-20 AU AU41959/99A patent/AU760527C/en not_active Ceased
- 1999-05-20 PL PL99344330A patent/PL344330A1/xx not_active Application Discontinuation
- 1999-05-20 JP JP2000550843A patent/JP2002516322A/ja not_active Withdrawn
- 1999-05-20 WO PCT/US1999/011260 patent/WO1999061437A1/en not_active Application Discontinuation
- 1999-05-20 TR TR2000/03472T patent/TR200003472T2/xx unknown
- 1999-05-20 CZ CZ20004339A patent/CZ20004339A3/cs unknown
- 1999-05-20 NZ NZ526958A patent/NZ526958A/xx unknown
- 1999-05-20 CN CN99806499A patent/CN1302296A/zh active Pending
- 1999-05-20 HU HU0102058A patent/HUP0102058A3/hu unknown
- 1999-05-20 CA CA002332402A patent/CA2332402A1/en not_active Abandoned
- 1999-05-20 IL IL13973299A patent/IL139732A0/xx unknown
- 1999-05-20 BR BR9910621-3A patent/BR9910621A/pt not_active Application Discontinuation
- 1999-05-20 CN CNA031577954A patent/CN1548436A/zh active Pending
- 1999-05-20 EP EP99925727A patent/EP1080087A4/en not_active Withdrawn
- 1999-05-20 NZ NZ508180A patent/NZ508180A/en unknown
-
2000
- 2000-11-20 ZA ZA200006761A patent/ZA200006761B/en unknown
- 2000-11-21 NO NO20005878A patent/NO20005878L/no not_active Application Discontinuation
-
2001
- 2001-03-03 US US09/701,460 patent/US6548520B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
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HUP0102058A2 (hu) | 2002-03-28 |
PL344330A1 (en) | 2001-10-22 |
NO20005878D0 (no) | 2000-11-21 |
AU4195999A (en) | 1999-12-13 |
CN1302296A (zh) | 2001-07-04 |
HUP0102058A3 (en) | 2002-05-28 |
JP2002516322A (ja) | 2002-06-04 |
TR200003472T2 (tr) | 2001-09-21 |
BR9910621A (pt) | 2001-01-30 |
EP1080087A4 (en) | 2001-11-21 |
NO20005878L (no) | 2000-11-21 |
US6548520B1 (en) | 2003-04-15 |
EP1080087A1 (en) | 2001-03-07 |
CN1548436A (zh) | 2004-11-24 |
WO1999061437A1 (en) | 1999-12-02 |
KR20010025087A (ko) | 2001-03-26 |
AU760527B2 (en) | 2003-05-15 |
NZ526958A (en) | 2004-12-24 |
AU760527C (en) | 2004-05-06 |
IL139732A0 (en) | 2002-02-10 |
CA2332402A1 (en) | 1999-12-02 |
NZ508180A (en) | 2003-09-26 |
CZ20004339A3 (cs) | 2001-10-17 |
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