YU9601A - Nove farmaceutske primene za inhibitore sintaze azotoksida - Google Patents
Nove farmaceutske primene za inhibitore sintaze azotoksidaInfo
- Publication number
- YU9601A YU9601A YU9601A YU9601A YU9601A YU 9601 A YU9601 A YU 9601A YU 9601 A YU9601 A YU 9601A YU 9601 A YU9601 A YU 9601A YU 9601 A YU9601 A YU 9601A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- combination
- nos
- treatment
- inhibitors
- alone
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/443—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Abstract
Ovaj se pronalazak odnosi na nove farmaceutske primene za jedinjenja koja ispoljavaju delovanje kao inhibitori azoroksidne sintaze (NOS). Tačnije, odnosi se na primenu NOS inhibitora, posebno selektivnih neuronskih NOS (N-NOS) inhibitora: (a) samih ili u kombinaciji sa drugim aktivnim agensom za lečenje psorijaze, (b) u kombinaciji sa nekim protivzapaljenskim sredstvom za lečenje zapaljenjskih poremećaja, (c) u kombinaciji sa nekim narkotičkim analgetikom (na primer opijatima kao što su morfijum ili demerol) za lečenje bola, (d) samih ili u kombinaciji sa drugim aktivnim agensima za poboljšanje spoznaje, i (e) samih ili u kombinaciji sa drugim aktivnim agensima za lečenje poremećaja spavanja kao što su nemogućnost disanja, sindrom spavanja i nesanica.[The present invention relates to new pharmaceutical uses for compounds that exhibit activity as nitric oxide synthase (NOS) inhibitors. Specifically, it relates to the use of NOS inhibitors, particularly selective neuronal NOS (N-NOS) inhibitors: (a) alone or in combination with another active agent for the treatment of psoriasis; (b) in combination with an antiinflammatory agent for the treatment of inflammatory disorders; (c) in combination with a narcotic analgesic (e.g., opiates such as morphine or demerol) for the treatment of pain; (d) alone or in combination with other active agents for the enhancement of cognition; and (e) alone or in combination with other active agents for the treatment of sleep disorders such as apnea, narcolepsy and insomnia.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9615298P | 1998-08-11 | 1998-08-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| YU9601A true YU9601A (sh) | 2003-12-31 |
Family
ID=22255853
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU9601A YU9601A (sh) | 1998-08-11 | 1999-08-05 | Nove farmaceutske primene za inhibitore sintaze azotoksida |
Country Status (37)
| Country | Link |
|---|---|
| US (1) | US20020151572A1 (sh) |
| EP (1) | EP1109556A2 (sh) |
| JP (1) | JP2002522498A (sh) |
| KR (1) | KR20010085364A (sh) |
| CN (1) | CN1323211A (sh) |
| AP (1) | AP2001002067A0 (sh) |
| AR (1) | AR020009A1 (sh) |
| AU (1) | AU749439B2 (sh) |
| BR (1) | BR9912906A (sh) |
| CA (1) | CA2340200A1 (sh) |
| CO (1) | CO5130011A1 (sh) |
| CR (1) | CR6302A (sh) |
| CZ (1) | CZ2001486A3 (sh) |
| DZ (1) | DZ2867A1 (sh) |
| EA (1) | EA200100125A1 (sh) |
| EE (1) | EE200100084A (sh) |
| GE (1) | GEP20043252B (sh) |
| GT (1) | GT199900127A (sh) |
| HK (1) | HK1041819A1 (sh) |
| HR (1) | HRP20010099A2 (sh) |
| HU (1) | HUP0103113A3 (sh) |
| ID (1) | ID28227A (sh) |
| IL (1) | IL141031A0 (sh) |
| IS (1) | IS5814A (sh) |
| MA (1) | MA26670A1 (sh) |
| NO (1) | NO20010685L (sh) |
| NZ (1) | NZ509298A (sh) |
| OA (1) | OA11595A (sh) |
| PA (1) | PA8479801A1 (sh) |
| PE (1) | PE20001025A1 (sh) |
| PL (1) | PL346842A1 (sh) |
| SK (1) | SK1702001A3 (sh) |
| SV (1) | SV1999000121A (sh) |
| TN (1) | TNSN99154A1 (sh) |
| TR (3) | TR200401803T2 (sh) |
| WO (1) | WO2000009130A2 (sh) |
| YU (1) | YU9601A (sh) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20010049379A1 (en) | 1997-08-27 | 2001-12-06 | Lowe John Adams | 2-aminopyridines containing fused ring substituents |
| JP2003523405A (ja) | 2000-02-22 | 2003-08-05 | セレジー カナダ インコーポレイテッド | 睡眠改善のための方法および組成物 |
| US20030219494A1 (en) * | 2002-03-20 | 2003-11-27 | Smith Maree Therese | Compositions and methods of using them |
| WO2005007627A1 (ja) * | 2003-07-18 | 2005-01-27 | Nihon Nohyaku Co., Ltd. | フェニルピリジン誘導体、その中間体及びこれを有効成分とする除草剤 |
| WO2014138460A1 (en) | 2013-03-07 | 2014-09-12 | Northwestern University | 2-aminopyridine-based selective neuronal nitric oxide synthase inhibitors |
| US9951014B2 (en) | 2014-11-04 | 2018-04-24 | Northwestern University | Mammalian and bacterial nitric oxide synthase inhibitors |
| US10759791B2 (en) | 2014-11-04 | 2020-09-01 | Northwestern University | Mammalian and bacterial nitric oxide synthase inhibitors |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT891332E (pt) * | 1996-03-29 | 2004-07-30 | Pfizer | Derivados de 6-fenilpiridil-2-amina |
| HN1997000027A (es) * | 1996-12-06 | 1997-06-05 | Pfizer Prod Inc | Derivados de 6-fenil piridil - 2 amina |
| BR9811093A (pt) * | 1997-02-10 | 2000-07-18 | Pfizer Prod Inc | Piridinas substituìdas com 2-amino-6-(4-fenóxi 2-substituìdo) |
| HN1998000118A (es) * | 1997-08-27 | 1999-02-09 | Pfizer Prod Inc | 2 - aminopiridinas que contienen sustituyentes de anillos condensados. |
| HN1998000125A (es) * | 1997-08-28 | 1999-02-09 | Pfizer Prod Inc | 2-aminopiridinas con sustituyentes alcoxi ramificados |
| SE9703693D0 (sv) * | 1997-10-10 | 1997-10-10 | Astra Pharma Prod | Novel combination |
-
1999
- 1999-08-05 EE EEP200100084A patent/EE200100084A/xx unknown
- 1999-08-05 EA EA200100125A patent/EA200100125A1/ru unknown
- 1999-08-05 BR BR9912906-0A patent/BR9912906A/pt not_active IP Right Cessation
- 1999-08-05 PL PL99346842A patent/PL346842A1/xx not_active Application Discontinuation
- 1999-08-05 CN CN99811907A patent/CN1323211A/zh active Pending
- 1999-08-05 HU HU0103113A patent/HUP0103113A3/hu unknown
- 1999-08-05 EP EP99933077A patent/EP1109556A2/en not_active Withdrawn
- 1999-08-05 TR TR2004/01803T patent/TR200401803T2/xx unknown
- 1999-08-05 WO PCT/IB1999/001389 patent/WO2000009130A2/en not_active Application Discontinuation
- 1999-08-05 TR TR2001/03661T patent/TR200103661T2/xx unknown
- 1999-08-05 KR KR1020017001788A patent/KR20010085364A/ko not_active Application Discontinuation
- 1999-08-05 AU AU49248/99A patent/AU749439B2/en not_active Ceased
- 1999-08-05 YU YU9601A patent/YU9601A/sh unknown
- 1999-08-05 ID IDW20010317A patent/ID28227A/id unknown
- 1999-08-05 CZ CZ2001486A patent/CZ2001486A3/cs unknown
- 1999-08-05 NZ NZ509298A patent/NZ509298A/en unknown
- 1999-08-05 GE GEAP19995742A patent/GEP20043252B/en unknown
- 1999-08-05 AP APAP/P/2001/002067A patent/AP2001002067A0/en unknown
- 1999-08-05 TR TR2001/00434T patent/TR200100434T2/xx unknown
- 1999-08-05 SK SK170-2001A patent/SK1702001A3/sk unknown
- 1999-08-05 IL IL14103199A patent/IL141031A0/xx unknown
- 1999-08-05 CA CA002340200A patent/CA2340200A1/en not_active Abandoned
- 1999-08-05 JP JP2000564633A patent/JP2002522498A/ja active Pending
- 1999-08-05 OA OA1200100036A patent/OA11595A/en unknown
- 1999-08-06 PA PA19998479801A patent/PA8479801A1/es unknown
- 1999-08-09 GT GT199900127A patent/GT199900127A/es unknown
- 1999-08-09 PE PE1999000801A patent/PE20001025A1/es not_active Application Discontinuation
- 1999-08-10 SV SV1999000121A patent/SV1999000121A/es not_active Application Discontinuation
- 1999-08-10 AR ARP990103995A patent/AR020009A1/es unknown
- 1999-08-10 DZ DZ990167A patent/DZ2867A1/xx active
- 1999-08-10 TN TNTNSN99154A patent/TNSN99154A1/fr unknown
- 1999-08-10 MA MA25724A patent/MA26670A1/fr unknown
- 1999-08-11 US US09/372,352 patent/US20020151572A1/en not_active Abandoned
- 1999-08-11 CO CO99051077A patent/CO5130011A1/es unknown
-
2001
- 2001-01-16 IS IS5814A patent/IS5814A/is unknown
- 2001-02-06 CR CR6302A patent/CR6302A/es not_active Application Discontinuation
- 2001-02-08 HR HR20010099A patent/HRP20010099A2/hr not_active Application Discontinuation
- 2001-02-09 NO NO20010685A patent/NO20010685L/no not_active Application Discontinuation
-
2002
- 2002-05-13 HK HK02103597.9A patent/HK1041819A1/zh unknown
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