YU6687A - New thieno-1,4-diazepines - Google Patents

New thieno-1,4-diazepines

Info

Publication number
YU6687A
YU6687A YU00066/87A YU6687A YU6687A YU 6687 A YU6687 A YU 6687A YU 00066/87 A YU00066/87 A YU 00066/87A YU 6687 A YU6687 A YU 6687A YU 6687 A YU6687 A YU 6687A
Authority
YU
Yugoslavia
Prior art keywords
diazepines
new thieno
thieno
new
Prior art date
Application number
YU00066/87A
Other languages
English (en)
Inventor
W Stransky
K H Weber
G Walter
A Harreus
J C Stenzel
G Maucevic
W D Bechtel
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of YU6687A publication Critical patent/YU6687A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
YU00066/87A 1986-01-21 1987-01-19 New thieno-1,4-diazepines YU6687A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3601557 1986-01-21
DE3624646 1986-07-22

Publications (1)

Publication Number Publication Date
YU6687A true YU6687A (en) 1990-12-31

Family

ID=25840265

Family Applications (1)

Application Number Title Priority Date Filing Date
YU00066/87A YU6687A (en) 1986-01-21 1987-01-19 New thieno-1,4-diazepines

Country Status (18)

Country Link
US (1) US4900729A (cs)
EP (1) EP0230942B1 (cs)
KR (1) KR870007180A (cs)
AU (1) AU594739B2 (cs)
CA (1) CA1314880C (cs)
DE (1) DE3778559D1 (cs)
DK (1) DK28787A (cs)
ES (1) ES2037013T3 (cs)
FI (1) FI870192A7 (cs)
GR (1) GR3004475T3 (cs)
HU (1) HUT45258A (cs)
IL (1) IL81322A0 (cs)
NO (1) NO166367C (cs)
NZ (1) NZ219015A (cs)
PH (1) PH27029A (cs)
PL (1) PL263736A1 (cs)
PT (1) PT84149B (cs)
YU (1) YU6687A (cs)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3502392A1 (de) * 1985-01-25 1986-07-31 Boehringer Ingelheim KG, 6507 Ingelheim Neue thieno-triazolo-1,4-diazepino-2- carbonsaeureamide, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
DE3610848A1 (de) * 1986-04-01 1987-10-15 Boehringer Ingelheim Kg Neue 1,4-diazepine
PH30676A (en) * 1986-07-22 1997-09-16 Boehringer Ingelhein Kg Hetrazepine compounds which have useful pharmaceutical utility
WO1988009333A1 (fr) * 1987-05-28 1988-12-01 Yoshitomi Pharmaceutical Industries, Ltd. Compose a base de thieno(triazolo)diazepine et applications medicales de ce compose
US5028603A (en) * 1987-06-08 1991-07-02 Yoshitomi Pharmaceutical Industries, Ltd. Ester-substituted thienotriazolodiazepine compounds and pharmaceutical uses thereof
US5895785A (en) * 1987-10-20 1999-04-20 Ruth Korth Treatment and prevention of disorders mediated by LA-paf or endothelial cells
EP0540766A1 (en) * 1991-11-04 1993-05-12 Korth, Ruth-Maria, Dr. med Treatment of eosinophil-mediated diseases with Paf antagonists and procedure for determining their efficacy.
US5530023A (en) * 1987-10-20 1996-06-25 Korth; Ruth Production of binding sites for PAF, PAF analogues and PAF antagonists in endothelial cells
US5480881A (en) * 1990-06-01 1996-01-02 Korth; Ruth Treatment of disease with paf-acether antagonists and procedure determining their efficacy
MC1999A1 (fr) * 1987-12-18 1990-01-26 Hoffmann La Roche Composes tricycliques
CA1324863C (en) * 1988-01-30 1993-11-30 Minoru Moriwaki Thienotriazolodiazepine compounds and pharmaceutical uses thereof
EP0338993A1 (en) * 1988-04-21 1989-10-25 Sandoz Ag 6-Aryl-substituted-4h-thieno[2,3-e][1,2,4]triazolo [3,4-c][1,4]diazepines
CA1322367C (en) * 1988-05-17 1993-09-21 Yoshitomi Pharmaceutical Industries Ltd. Thienotriazolodiazepine compounds and pharmaceutical uses thereof
IL91386A0 (en) * 1988-08-24 1990-04-29 Boehringer Ingelheim Kg Method for treating autoimmune diseases by using a paf antagonist and pharmaceutical compositions comprising it
RU2117670C1 (ru) * 1988-10-31 1998-08-20 Эйсай Ко., Лтд. Производные триазоло[1,4]диазепина и способы их получения
FI95708C (fi) 1988-10-31 1996-03-11 Eisai Co Ltd Analogiamenetelmä 1,4-diatsepiinijohdannaisen ja sen farmaseuttisesti sopivan suolan valmistamiseksi
EP0387613A1 (de) * 1989-03-03 1990-09-19 Boehringer Ingelheim Kg Neue Thienodiazepine
EP0389189B1 (en) * 1989-03-23 1994-05-18 Pfizer Limited Diazepine antiallergy agents
CA2020806A1 (en) * 1989-07-12 1991-01-13 Karl-Heinz Weber Thienodiazepine derivatives
FR2659332B1 (fr) * 1990-03-08 1994-04-29 Adit Et Cie Nouvelles pyrrolo [1,2-a] thieno [3,2-f] diazepines [1,4], leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
DE4010528A1 (de) * 1990-04-02 1991-10-17 Boehringer Ingelheim Kg Praeparativ chromatographisches trennverfahren zur herstellung enantiomerenreiner hetrazepine
DE4027470A1 (de) * 1990-08-30 1992-03-05 Boehringer Ingelheim Kg Neue hetrazepinoide amide
DE4107521A1 (de) * 1991-03-08 1992-09-10 Boehringer Ingelheim Kg Neue acylaminosubstituierte hetrazepine
DE540767T1 (de) * 1991-11-04 2001-10-25 Ruth-Maria Korth Behandlung und Vorbeugung von von erhöhten Lyso-PAF-Spiegel mediierten mentalen Erkrankungen mit PAF-Antagonisten
CN1642924A (zh) * 2002-03-28 2005-07-20 威斯技术基金会公司 减少了镇静与共济失调效果的抗焦虑剂
US20100261711A1 (en) * 2009-03-20 2010-10-14 Wisys Technology Foundation Selective anticonvulsant agents and their uses
JP2017504651A (ja) 2014-01-31 2017-02-09 ダナ−ファーバー キャンサー インスティテュート, インコーポレイテッド ジアゼパン誘導体の使用
KR101675984B1 (ko) 2015-02-23 2016-11-14 한양대학교 에리카산학협력단 티에노디아제핀 유도체 또는 이의 약학적으로 허용가능한 염, 및 이를 유효성분으로 포함하는 약학적 조성물
US11306105B2 (en) * 2015-09-11 2022-04-19 Dana-Farber Cancer Institute, Inc. Cyano thienotriazolodiazepines and uses thereof
US10913752B2 (en) 2015-11-25 2021-02-09 Dana-Farber Cancer Institute, Inc. Bivalent bromodomain inhibitors and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH12303A (en) * 1973-02-08 1979-01-16 Hoffmann La Roche Thienotriazolodiazepine derivatives
CH612972A5 (en) * 1974-01-16 1979-08-31 Hoffmann La Roche Process for the preparation of thieno-triazolo-diazepine derivatives
US4307237A (en) * 1974-09-11 1981-12-22 Hoffmann-La Roche Inc. Imidazoles
FI63033C (fi) * 1977-07-21 1983-04-11 Boehringer Sohn Ingelheim Foerfarande foer framstaellning av anxiolytiska tranquilliserande sedativa och/eller neuroleptiska substituerade 1-piperazinyl-4h-s-triazolo(3,4-c)tieno(2,3-e)-1,4-diazepiner
DE3435973A1 (de) * 1984-10-01 1986-04-10 Boehringer Ingelheim KG, 6507 Ingelheim Diazepine enthaltende pharmazeutische zusammensetzungen mit paf-antagonistischer wirkung
DE3502392A1 (de) * 1985-01-25 1986-07-31 Boehringer Ingelheim KG, 6507 Ingelheim Neue thieno-triazolo-1,4-diazepino-2- carbonsaeureamide, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
DE3610848A1 (de) * 1986-04-01 1987-10-15 Boehringer Ingelheim Kg Neue 1,4-diazepine
PH30676A (en) * 1986-07-22 1997-09-16 Boehringer Ingelhein Kg Hetrazepine compounds which have useful pharmaceutical utility

Also Published As

Publication number Publication date
NO870240D0 (no) 1987-01-20
NZ219015A (en) 1990-01-29
FI870192A0 (fi) 1987-01-19
DK28787D0 (da) 1987-01-20
ES2037013T3 (es) 1993-06-16
DE3778559D1 (de) 1992-06-04
NO166367C (no) 1991-07-10
KR870007180A (ko) 1987-08-17
PT84149B (pt) 1989-07-31
AU6784587A (en) 1987-07-23
AU594739B2 (en) 1990-03-15
FI870192A7 (fi) 1987-07-22
IL81322A0 (en) 1987-08-31
CA1314880C (en) 1993-03-23
NO166367B (no) 1991-04-02
US4900729A (en) 1990-02-13
EP0230942A3 (en) 1989-03-08
PL263736A1 (en) 1988-07-21
EP0230942A2 (de) 1987-08-05
PT84149A (de) 1987-02-01
DK28787A (da) 1987-07-22
EP0230942B1 (de) 1992-04-29
PH27029A (en) 1993-02-01
NO870240L (no) 1987-07-22
GR3004475T3 (cs) 1993-03-31
HUT45258A (en) 1988-06-28

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