YU64000A - Stabilne kompozicije koje sadrže levosimendan i alginsku kiselinu - Google Patents

Stabilne kompozicije koje sadrže levosimendan i alginsku kiselinu

Info

Publication number
YU64000A
YU64000A YU64000A YU64000A YU64000A YU 64000 A YU64000 A YU 64000A YU 64000 A YU64000 A YU 64000A YU 64000 A YU64000 A YU 64000A YU 64000 A YU64000 A YU 64000A
Authority
YU
Yugoslavia
Prior art keywords
levosimendan
alginic acid
compositions
stabile
stabile compositions
Prior art date
Application number
YU64000A
Other languages
English (en)
Inventor
Ilkka Larma
Maarit Backman
Original Assignee
Orion Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Corporation filed Critical Orion Corporation
Publication of YU64000A publication Critical patent/YU64000A/sh
Publication of RS49955B publication Critical patent/RS49955B/sr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • Detergent Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

Ovaj pronalazak se odnosi na farmaceutske kompozicije levosimendana koje sadrže alginsku kiselinu kao sredstvo za poboljšanje stabilnosti levosimendana u kompozicijama. Levosimendan je koristan u tretiranju kongestivnog srčanog udara.[The present invention relates to pharmaceutical compositions of levosimendan comprising alginic acid for improving the stability of levosimendan in the compositions. Levosimendan is useful in the treatment of congestive heart failure.
YUP-640/00A 1998-04-23 1999-04-23 Stabilne kompozicije koje sadrže levosimendan i alginsku kiselinu RS49955B (sr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI980902A FI980902A (fi) 1998-04-23 1998-04-23 Levosimendaanin stabiileja koostumuksia

Publications (2)

Publication Number Publication Date
YU64000A true YU64000A (sh) 2002-12-10
RS49955B RS49955B (sr) 2008-09-29

Family

ID=8551576

Country Status (33)

Country Link
US (1) US6531458B1 (sh)
EP (1) EP1079834B1 (sh)
JP (1) JP4475809B2 (sh)
KR (1) KR100590622B1 (sh)
CN (1) CN1165309C (sh)
AT (1) ATE231395T1 (sh)
AU (1) AU756338B2 (sh)
BG (1) BG64766B1 (sh)
BR (1) BR9909867A (sh)
CA (1) CA2329232C (sh)
CZ (1) CZ290911B6 (sh)
DE (1) DE69905034T2 (sh)
DK (1) DK1079834T3 (sh)
EA (1) EA002428B1 (sh)
EE (1) EE04143B1 (sh)
ES (1) ES2191426T3 (sh)
FI (1) FI980902A (sh)
GE (1) GEP20032942B (sh)
HK (1) HK1031998A1 (sh)
HR (1) HRP20000703B1 (sh)
HU (1) HUP0105446A3 (sh)
ID (1) ID26650A (sh)
IL (2) IL138950A0 (sh)
MX (1) MXPA00010368A (sh)
NO (1) NO318575B1 (sh)
NZ (1) NZ507455A (sh)
PL (1) PL192274B1 (sh)
PT (1) PT1079834E (sh)
RS (1) RS49955B (sh)
SK (1) SK284600B6 (sh)
TR (1) TR200003101T2 (sh)
WO (1) WO1999055337A1 (sh)
ZA (1) ZA200005630B (sh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI980901A (fi) * 1998-04-23 1999-10-24 Orion Yhtymae Oyj Levosimendaania säädellysti vapauttavia oraalisia koostumuksia
FI109659B (fi) * 1999-09-10 2002-09-30 Orion Yhtymae Oyj Levosimendaanin farmaseuttisia liuoksia
FI20010233A0 (fi) * 2001-02-08 2001-02-08 Orion Corp Menetelmä sydämen vajaatoiminnan hoitoon
EP1366761A4 (en) * 2001-02-13 2004-04-21 Taisho Pharmaceutical Co Ltd GEL PREPARATIONS FOR INTERNAL USE
JP2008533109A (ja) * 2005-03-14 2008-08-21 オリオン コーポレーション 利尿を促進するための複合治療
CN108289832B (zh) * 2015-11-06 2021-08-31 卡利努法姆股份有限公司 用于以输注或注射形式进行静脉给药的左西孟旦以及输注浓缩液的改善配方
AU2020408323A1 (en) 2019-12-16 2022-08-11 Tenax Therapeutics, Inc. Levosimendan for treating pulmonary hypertension with heart failure with preserved ejection fraction (PH-HF-pEF)

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1509866A (en) 1975-06-10 1978-05-04 Johnson & Johnson Enteric coated digestive enzyme compositions
PT76448B (en) 1982-04-05 1986-03-20 Merck Sharp & Dohme Process for preparing stabilization of unstable drugs or food supplements containing antibiotics mainly ephrotomycin
EP0123291A2 (en) 1983-04-20 1984-10-31 Kyowa Hakko Kogyo Co., Ltd. Method for stabilizing interferon
US4906630A (en) * 1985-11-22 1990-03-06 Rorer Pharmaceutical Corporation Method of increasing cardiac contractility using pharmaceutical compositions comprising benzodiazinone- pyridazinone or hydroxy-pyrazolyl compounds
US4716042A (en) * 1986-06-16 1987-12-29 American Home Products Corporation Stabilized coated aspirin tablets
GB8903130D0 (en) 1989-02-11 1989-03-30 Orion Yhtymae Oy Substituted pyridazinones
GB2251615B (en) * 1991-01-03 1995-02-08 Orion Yhtymae Oy (-)-[[4-(1,4,5,6-tetrahydro-4-methyl-6-oxo-3-pyridazinyl)phenyl]hydrazono]pro panedinitrile
GB2266841A (en) 1992-05-06 1993-11-17 Orion Yhtymae Oy Compounds for use as anti-ischemic medicaments
GB9614098D0 (en) * 1996-07-05 1996-09-04 Orion Yhtymae Oy Transdermal delivery of levosimendan
FI973804A (fi) * 1997-09-26 1999-03-27 Orion Yhtymae Oy Levosimendaanin oraalisia koostumuksia

Also Published As

Publication number Publication date
CZ290911B6 (cs) 2002-11-13
CA2329232A1 (en) 1999-11-04
US6531458B1 (en) 2003-03-11
EE04143B1 (et) 2003-10-15
EE200000616A (et) 2002-06-17
CA2329232C (en) 2007-10-30
HK1031998A1 (en) 2001-07-06
DE69905034D1 (de) 2003-02-27
EA002428B1 (ru) 2002-04-25
IL138950A (en) 2006-08-20
WO1999055337A1 (en) 1999-11-04
NO318575B1 (no) 2005-04-11
ID26650A (id) 2001-01-25
BG64766B1 (bg) 2006-03-31
PL192274B1 (pl) 2006-09-29
MXPA00010368A (es) 2002-07-02
FI980902A0 (fi) 1998-04-23
PT1079834E (pt) 2003-04-30
CN1165309C (zh) 2004-09-08
KR100590622B1 (ko) 2006-06-19
HRP20000703A2 (en) 2001-04-30
JP4475809B2 (ja) 2010-06-09
SK284600B6 (sk) 2005-07-01
EP1079834A1 (en) 2001-03-07
IL138950A0 (en) 2001-11-25
ATE231395T1 (de) 2003-02-15
HRP20000703B1 (en) 2009-11-30
DK1079834T3 (da) 2003-04-07
ZA200005630B (en) 2002-01-14
NO20005312L (no) 2000-11-21
FI980902A (fi) 1999-10-24
EP1079834B1 (en) 2003-01-22
BG104958A (en) 2001-07-31
KR20010072577A (ko) 2001-07-31
NZ507455A (en) 2002-02-01
PL343722A1 (en) 2001-09-10
CZ20003779A3 (en) 2001-05-16
NO20005312D0 (no) 2000-10-20
RS49955B (sr) 2008-09-29
CN1298303A (zh) 2001-06-06
GEP20032942B (en) 2003-04-25
SK15552000A3 (sk) 2001-05-10
AU3524899A (en) 1999-11-16
ES2191426T3 (es) 2003-09-01
BR9909867A (pt) 2000-12-19
HUP0105446A2 (hu) 2002-07-29
JP2002512964A (ja) 2002-05-08
TR200003101T2 (tr) 2001-01-22
EA200001097A1 (ru) 2001-04-23
AU756338B2 (en) 2003-01-09
DE69905034T2 (de) 2003-09-04
HUP0105446A3 (en) 2002-09-30

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