YU54402A - Antagonisti faktora otpuštanja kortikotropina - Google Patents
Antagonisti faktora otpuštanja kortikotropinaInfo
- Publication number
- YU54402A YU54402A YU54402A YUP54402A YU54402A YU 54402 A YU54402 A YU 54402A YU 54402 A YU54402 A YU 54402A YU P54402 A YUP54402 A YU P54402A YU 54402 A YU54402 A YU 54402A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- releasing factor
- corticotropin releasing
- factor antagonists
- antagonists
- corticotropin
- Prior art date
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
- C07D213/643—2-Phenoxypyridines; Derivatives thereof
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Abstract
Antagonisti faktora otpuštanja kortikotropina (CRF) koji imaju formule (I), (II), ili (III), gde su isprekidane linije, A, B, Y, Z, G, R3, R4, R5 R6, R16 I R17 kako je definisano u prijavi, i postupcima za njihovo dobijanje. Ova jedinjenja i njihove farmaceutski prihvatljive soli su korisne u tretmanu poremećaja koji uključuju CNS i poremećaje vezane za stres.[Corticotropin-releasing factor (CRF) antagonists having the formulae (I), (II) or (III), wherein the dashed lines, A, B, Y, Z, G, R3, R4, R5, R6, R16 and R17 are as defined in the application, and processes for preparing them. These compounds and their pharmaceutically acceptable salts are useful in the treatment disorders including CNS and stress-related disorders.
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US17661100P | 2000-01-18 | 2000-01-18 |
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AU (1) | AU779995B2 (sh) |
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CA (1) | CA2397633A1 (sh) |
CO (1) | CO5271658A1 (sh) |
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HN (1) | HN2001000006A (sh) |
HR (1) | HRP20020599A2 (sh) |
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NO (1) | NO20023424L (sh) |
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PA (1) | PA8510001A1 (sh) |
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SV (1) | SV2002000289A (sh) |
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UY (1) | UY26544A1 (sh) |
WO (1) | WO2001053263A1 (sh) |
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