YU52598A - POSTUPAK ZA sintezu N-[2[[[5=[(DIALKILAMINO)METIL]-2= FURANIL]METIL]TIO]ETIL]-N'-ALKIL-2-NITRO 1,1 ALKENDIAMINA I NJIHOVIH HIDROHLORIDA - Google Patents

POSTUPAK ZA sintezu N-[2[[[5=[(DIALKILAMINO)METIL]-2= FURANIL]METIL]TIO]ETIL]-N'-ALKIL-2-NITRO 1,1 ALKENDIAMINA I NJIHOVIH HIDROHLORIDA

Info

Publication number
YU52598A
YU52598A YU52598A YU52598A YU52598A YU 52598 A YU52598 A YU 52598A YU 52598 A YU52598 A YU 52598A YU 52598 A YU52598 A YU 52598A YU 52598 A YU52598 A YU 52598A
Authority
YU
Yugoslavia
Prior art keywords
methyl
nitro
alkyl
dialkylamino
hydrochloride
Prior art date
Application number
YU52598A
Other languages
English (en)
Inventor
Slobodan Stanković
Nebojša Stojanović
Stanislava Stopičić
Dragan Milenović
Original Assignee
D.D. Zdravlje- sektor za istraživanje i razvoj
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by D.D. Zdravlje- sektor za istraživanje i razvoj filed Critical D.D. Zdravlje- sektor za istraživanje i razvoj
Priority to YU52598A priority Critical patent/YU52598A/sh
Priority to AU14798/00A priority patent/AU1479800A/en
Priority to PCT/YU1999/000011 priority patent/WO2000029400A2/en
Publication of YU52598A publication Critical patent/YU52598A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Furan Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Pronalazak se odnosi na postupak za dobijanje terapeutski aktivnih N-[2[[[5-[dialkilamino) metil]tio]etil]-N'-alkil-2-nitro 1,1 alkendiamina formule (I) i njihovih hidrohlorida formule (II) u kojoj su R1, R2 i R3 - alkil grupe (C1-C4), a X je nitro-alkenska grupa reakcijom 2-[[[5-[dimetilamino)metil-2-furanil]metil]tio]-etanaminhidrohlorida i N-metil-1(metiltio)-2-nitroetanamina u vodenoj sredini pri blagoj temperaturi.
YU52598A 1998-11-19 1998-11-19 POSTUPAK ZA sintezu N-[2[[[5=[(DIALKILAMINO)METIL]-2= FURANIL]METIL]TIO]ETIL]-N'-ALKIL-2-NITRO 1,1 ALKENDIAMINA I NJIHOVIH HIDROHLORIDA YU52598A (sh)

Priority Applications (3)

Application Number Priority Date Filing Date Title
YU52598A YU52598A (sh) 1998-11-19 1998-11-19 POSTUPAK ZA sintezu N-[2[[[5=[(DIALKILAMINO)METIL]-2= FURANIL]METIL]TIO]ETIL]-N'-ALKIL-2-NITRO 1,1 ALKENDIAMINA I NJIHOVIH HIDROHLORIDA
AU14798/00A AU1479800A (en) 1998-11-19 1999-11-18 Procedure for synthesis of N-(2(((5-((dialkilamino) methyl)-2- furanyl) methyl)thyo) ethyl)-N'- alkyl-2-nitro1,1 alkenediamines and their hydrochlorides
PCT/YU1999/000011 WO2000029400A2 (en) 1998-11-19 1999-11-18 Procedure for synthesis of n-[2[[[5- [(dialkilamino) methyl]-2- furanyl] methyl]thyo] ethyl]-n'- alkyl-2-nitro1,1 alkenediamines and their hydrochlorides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
YU52598A YU52598A (sh) 1998-11-19 1998-11-19 POSTUPAK ZA sintezu N-[2[[[5=[(DIALKILAMINO)METIL]-2= FURANIL]METIL]TIO]ETIL]-N'-ALKIL-2-NITRO 1,1 ALKENDIAMINA I NJIHOVIH HIDROHLORIDA

Publications (1)

Publication Number Publication Date
YU52598A true YU52598A (sh) 2001-05-28

Family

ID=25550316

Family Applications (1)

Application Number Title Priority Date Filing Date
YU52598A YU52598A (sh) 1998-11-19 1998-11-19 POSTUPAK ZA sintezu N-[2[[[5=[(DIALKILAMINO)METIL]-2= FURANIL]METIL]TIO]ETIL]-N'-ALKIL-2-NITRO 1,1 ALKENDIAMINA I NJIHOVIH HIDROHLORIDA

Country Status (3)

Country Link
AU (1) AU1479800A (sh)
WO (1) WO2000029400A2 (sh)
YU (1) YU52598A (sh)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107382922A (zh) * 2017-08-03 2017-11-24 江苏汉斯通药业有限公司 高透光度盐酸雷尼替丁的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1565966A (en) * 1976-08-04 1980-04-23 Allen & Hanburys Ltd Aminoalkyl furan derivatives
FI72318C (fi) * 1976-08-04 1987-05-11 Allen & Hanburys Ltd Foerfarande foer framstaellning av selektivt pao histaminreseptorer verkande n-/2-///5-(dimetylamino)metyl -2-furanyl/metyl/tio/etyl-n'-metyl-2-nitro-1,1-etendiamin.
DE3170346D1 (en) * 1980-12-30 1985-06-05 Glaxo Group Ltd Process for the preparation of a furan derivative
GB8415254D0 (en) * 1984-06-15 1984-07-18 Glaxo Group Ltd Amine derivatives
EP0697411B1 (en) * 1994-06-24 1998-07-01 Ranbaxy Laboratories Limited Process for the manufacture of pharmaceutical grade ranitidine base

Also Published As

Publication number Publication date
AU1479800A (en) 2000-06-05
WO2000029400A2 (en) 2000-05-25
WO2000029400A3 (en) 2000-07-20

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