YU52598A - POSTUPAK ZA sintezu N-[2[[[5=[(DIALKILAMINO)METIL]-2= FURANIL]METIL]TIO]ETIL]-N'-ALKIL-2-NITRO 1,1 ALKENDIAMINA I NJIHOVIH HIDROHLORIDA - Google Patents
POSTUPAK ZA sintezu N-[2[[[5=[(DIALKILAMINO)METIL]-2= FURANIL]METIL]TIO]ETIL]-N'-ALKIL-2-NITRO 1,1 ALKENDIAMINA I NJIHOVIH HIDROHLORIDAInfo
- Publication number
- YU52598A YU52598A YU52598A YU52598A YU52598A YU 52598 A YU52598 A YU 52598A YU 52598 A YU52598 A YU 52598A YU 52598 A YU52598 A YU 52598A YU 52598 A YU52598 A YU 52598A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- methyl
- nitro
- alkyl
- dialkylamino
- hydrochloride
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Furan Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Pronalazak se odnosi na postupak za dobijanje terapeutski aktivnih N-[2[[[5-[dialkilamino) metil]tio]etil]-N'-alkil-2-nitro 1,1 alkendiamina formule (I) i njihovih hidrohlorida formule (II) u kojoj su R1, R2 i R3 - alkil grupe (C1-C4), a X je nitro-alkenska grupa reakcijom 2-[[[5-[dimetilamino)metil-2-furanil]metil]tio]-etanaminhidrohlorida i N-metil-1(metiltio)-2-nitroetanamina u vodenoj sredini pri blagoj temperaturi.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
YU52598A YU52598A (sh) | 1998-11-19 | 1998-11-19 | POSTUPAK ZA sintezu N-[2[[[5=[(DIALKILAMINO)METIL]-2= FURANIL]METIL]TIO]ETIL]-N'-ALKIL-2-NITRO 1,1 ALKENDIAMINA I NJIHOVIH HIDROHLORIDA |
AU14798/00A AU1479800A (en) | 1998-11-19 | 1999-11-18 | Procedure for synthesis of N-(2(((5-((dialkilamino) methyl)-2- furanyl) methyl)thyo) ethyl)-N'- alkyl-2-nitro1,1 alkenediamines and their hydrochlorides |
PCT/YU1999/000011 WO2000029400A2 (en) | 1998-11-19 | 1999-11-18 | Procedure for synthesis of n-[2[[[5- [(dialkilamino) methyl]-2- furanyl] methyl]thyo] ethyl]-n'- alkyl-2-nitro1,1 alkenediamines and their hydrochlorides |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
YU52598A YU52598A (sh) | 1998-11-19 | 1998-11-19 | POSTUPAK ZA sintezu N-[2[[[5=[(DIALKILAMINO)METIL]-2= FURANIL]METIL]TIO]ETIL]-N'-ALKIL-2-NITRO 1,1 ALKENDIAMINA I NJIHOVIH HIDROHLORIDA |
Publications (1)
Publication Number | Publication Date |
---|---|
YU52598A true YU52598A (sh) | 2001-05-28 |
Family
ID=25550316
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU52598A YU52598A (sh) | 1998-11-19 | 1998-11-19 | POSTUPAK ZA sintezu N-[2[[[5=[(DIALKILAMINO)METIL]-2= FURANIL]METIL]TIO]ETIL]-N'-ALKIL-2-NITRO 1,1 ALKENDIAMINA I NJIHOVIH HIDROHLORIDA |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU1479800A (sh) |
WO (1) | WO2000029400A2 (sh) |
YU (1) | YU52598A (sh) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107382922A (zh) * | 2017-08-03 | 2017-11-24 | 江苏汉斯通药业有限公司 | 高透光度盐酸雷尼替丁的制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1565966A (en) * | 1976-08-04 | 1980-04-23 | Allen & Hanburys Ltd | Aminoalkyl furan derivatives |
CY1077A (en) * | 1976-08-04 | 1980-12-27 | Allen & Hanburys Ltd | Aminoalkyl furan derivatives |
JPS57134475A (en) * | 1980-12-30 | 1982-08-19 | Glaxo Group Ltd | Manufacture of furan derivatives |
GB8415254D0 (en) * | 1984-06-15 | 1984-07-18 | Glaxo Group Ltd | Amine derivatives |
DE69503196T2 (de) * | 1994-06-24 | 1999-02-18 | Ranbaxy Lab Ltd | Verfahren zur Herstellung von Ranitdinbase in pharmazeutischer Reinheit |
-
1998
- 1998-11-19 YU YU52598A patent/YU52598A/sh unknown
-
1999
- 1999-11-18 WO PCT/YU1999/000011 patent/WO2000029400A2/en active Application Filing
- 1999-11-18 AU AU14798/00A patent/AU1479800A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU1479800A (en) | 2000-06-05 |
WO2000029400A3 (en) | 2000-07-20 |
WO2000029400A2 (en) | 2000-05-25 |
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