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Application filed by Krkatovarna Zdravil P.O.filedCriticalKrkatovarna Zdravil P.O.
Priority to YU197091ApriorityCriticalpatent/YU197091A/sh
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Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Nitrogen Condensed Heterocyclic Rings
(AREA)
Abstract
SUBSTITUIRANI PIPERAZINIL KINOLONI, POSTOPKI ZA NJIHOVO PRIPRAVO IN NJIHOVA UPORABA, opisani so novi substituirani piperazinilkinoloni s formulo I kjer je R1 etil, ciklopropil, 2-fluoroetil, t-butil, 4-fluorofenil, 2,4-difluorofenil, metilamino, X je N, CH ali CF, Y je N, CCl ali CF, R2 je H ali alkil z 1 do 4 atomi ogljika, R3 je ostanek s formulo II, III, IV ali V kjer je R4 nižji alkil, nižji alkil, substituiran z enim ali več halogeni, aromat ali heteroaromat, nesubstituiran ali substituiran z enim ali več halogeni, trihalometilenskimi, alkilnimi, alkiloksi ali acilnimi substituenti, kot tudi njihove farmacevtsko sprejemljive soli in solvati. Nove spojine so antimikrobno učinkovite.
YU197091A1991-12-201991-12-20Substituirani piperazinil kinoloni, postopki za njihovo pripravo in njihova uporaba
YU197091A
(sh)