YU126591A - Novi derivati 6-metil 19-nor progesterona supstituisanih u položaju 3 i postupak za njihovo dobijanje - Google Patents

Novi derivati 6-metil 19-nor progesterona supstituisanih u položaju 3 i postupak za njihovo dobijanje

Info

Publication number
YU126591A
YU126591A YU126591A YU126591A YU126591A YU 126591 A YU126591 A YU 126591A YU 126591 A YU126591 A YU 126591A YU 126591 A YU126591 A YU 126591A YU 126591 A YU126591 A YU 126591A
Authority
YU
Yugoslavia
Prior art keywords
methyl
progesterons
substituted
procedure
obtaining
Prior art date
Application number
YU126591A
Other languages
English (en)
Inventor
R. Bucourt
C. Tchernatinsky
A. Piasco
Original Assignee
Laboratoire Theramex Sa.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoire Theramex Sa. filed Critical Laboratoire Theramex Sa.
Publication of YU126591A publication Critical patent/YU126591A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/006—Ketals at position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C07J41/0016—Oximes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
    • C07J7/0045—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa not substituted in position 16

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

NOVI DERIVATI 6-METIL 19-NOR PROGESTERONA SUPSTITUISANIH U POLOŽAJU 3 I POSTUPAK ZA NJIHOVO DOBIJANJE, ovaj pronalazak se odnosi na oblast organske hemije i tačnije na medicinsku hemiju. Specifično se odnosi na 6-metil 19-nor pregna 4,6-dien 20-one opšte formule I gde R je vodonik, i R2 je OR3 ostatak u kome R3 je vodonik ili acil deo ili R1 i R2 zajedno grade oksimido grupu =N-OR4 ili po izboru supstituisanu alkilen dioksi grupu, i Ac je acil ostatak organske kaboksi kiseline. Jedinjenja opšte formule I su aktivni sastojci progesteronskih lekova.
YU126591A 1990-07-20 1991-07-18 Novi derivati 6-metil 19-nor progesterona supstituisanih u položaju 3 i postupak za njihovo dobijanje YU126591A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9009278A FR2664895B1 (fr) 1990-07-20 1990-07-20 Nouveaux derives de la 6-methyl 19-nor progesterone, substitues en 3 et leur procede d'obtention.

Publications (1)

Publication Number Publication Date
YU126591A true YU126591A (sh) 1994-05-10

Family

ID=9398932

Family Applications (1)

Application Number Title Priority Date Filing Date
YU126591A YU126591A (sh) 1990-07-20 1991-07-18 Novi derivati 6-metil 19-nor progesterona supstituisanih u položaju 3 i postupak za njihovo dobijanje

Country Status (11)

Country Link
EP (1) EP0491924A1 (sh)
FR (1) FR2664895B1 (sh)
IE (1) IE912539A1 (sh)
IL (1) IL98901A0 (sh)
MA (1) MA22229A1 (sh)
MX (1) MX9100291A (sh)
OA (1) OA09566A (sh)
PT (1) PT98415A (sh)
TN (1) TNSN91060A1 (sh)
WO (1) WO1992001706A1 (sh)
YU (1) YU126591A (sh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2695826B1 (fr) * 1992-09-21 1995-01-06 Theramex Nouvelles compositions pharmaceutiques à base de dérivés de nomégestrol et leurs procédés d'obtention.
GB0202873D0 (en) * 2002-02-07 2002-03-27 Novartis Ag Organic compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2219783B1 (sh) * 1973-03-01 1977-06-03 Ortho Pharma Corp
GB1515284A (en) * 1974-05-21 1978-06-21 Gastaud J Pharmaceutical compositions containing progestogens derived from the 17-alpha-hydroxy-19-nor-progesterone series
DE3204281C1 (de) * 1982-02-05 1983-07-21 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von 6-Methyl-delta?-3-ketosteroiden
FR2552766B1 (fr) * 1983-10-04 1987-06-26 Theramex Nouveau procede de preparation de derives de la serie du 17 a-hydroxy 19-nor progesterone

Also Published As

Publication number Publication date
OA09566A (fr) 1993-01-31
WO1992001706A1 (fr) 1992-02-06
IE912539A1 (en) 1992-01-29
IL98901A0 (en) 1992-07-15
MA22229A1 (fr) 1992-04-01
FR2664895B1 (fr) 1992-10-30
MX9100291A (es) 1992-02-28
EP0491924A1 (fr) 1992-07-01
FR2664895A1 (fr) 1992-01-24
TNSN91060A1 (fr) 1992-10-25
PT98415A (pt) 1992-05-29

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