YU111991A - Derivati aminokiselina - Google Patents

Derivati aminokiselina

Info

Publication number
YU111991A
YU111991A YU111991A YU111991A YU111991A YU 111991 A YU111991 A YU 111991A YU 111991 A YU111991 A YU 111991A YU 111991 A YU111991 A YU 111991A YU 111991 A YU111991 A YU 111991A
Authority
YU
Yugoslavia
Prior art keywords
amino acid
acid derivatives
mixtures
compounds
diastereomeric racemates
Prior art date
Application number
YU111991A
Other languages
English (en)
Inventor
Q. Branca
M.P. Heitz
M. Mueller
W. Neidhart
H. Stadler
E. Vieira
W. Wostl
Original Assignee
F. Hoffmann La Roche Ag.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann La Roche Ag. filed Critical F. Hoffmann La Roche Ag.
Publication of YU111991A publication Critical patent/YU111991A/sh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D263/06—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by oxygen atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

DERIVATI AMINOKISELINA, jedinjenja formule: u kojoj A, B, X, Y, R1' R2, R3, R4 i R5 imaju značenje dato u zatevu 1, u obliku optički čistih diastereomera, smeša diastereomera, diastereomernih racemata ili smeša diastereomernih racemata kao i farmaceutski primenljive soli ovih jedinjenja otežavaju dejstvo prirodnog encima renina i otuda se mogu primenjivati u obliku farmaceutskih preparata pri suzbijanju odnosno sprečavanju visokog krvnog pritiska i insuficijencije srca. Ona se mogu dobiti prema različitim, po sebi poznatim postupcima.
YU111991A 1990-06-28 1991-06-26 Derivati aminokiselina YU111991A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH215990 1990-06-28

Publications (1)

Publication Number Publication Date
YU111991A true YU111991A (sh) 1994-01-20

Family

ID=4227261

Family Applications (1)

Application Number Title Priority Date Filing Date
YU111991A YU111991A (sh) 1990-06-28 1991-06-26 Derivati aminokiselina

Country Status (18)

Country Link
EP (1) EP0464572A3 (sh)
JP (1) JPH04230380A (sh)
KR (1) KR920000762A (sh)
AU (1) AU642021B2 (sh)
BR (1) BR9102730A (sh)
CA (1) CA2044564A1 (sh)
FI (1) FI913179A (sh)
HU (1) HUT61299A (sh)
IE (1) IE912254A1 (sh)
IL (1) IL98576A0 (sh)
IS (1) IS3725A7 (sh)
MC (1) MC2264A1 (sh)
MX (1) MX26375A (sh)
NO (1) NO912537L (sh)
NZ (1) NZ238645A (sh)
PT (1) PT98123A (sh)
YU (1) YU111991A (sh)
ZA (1) ZA914808B (sh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW275630B (sh) * 1991-11-19 1996-05-11 Hoffmann La Roche
JP3135421B2 (ja) * 1993-07-06 2001-02-13 松下電子工業株式会社 カラー陰極線管
CN101087766B (zh) 2004-11-02 2011-09-07 西北大学 哒嗪化合物、组合物和方法
RS55630B1 (sr) 2005-12-21 2017-06-30 Janssen Pharmaceutica Nv Triazolopiridazini kao modulatori tirozin kinaze
PL2464645T3 (pl) 2009-07-27 2017-12-29 Gilead Sciences, Inc. Skondensowane heterocykliczne związki jako modulatory kanałów jonowych
CN103096977B (zh) 2010-07-02 2017-02-15 吉利德科学公司 作为离子通道调节剂的稠杂环化合物
MX361350B (es) 2011-05-10 2018-12-04 Gilead Sciences Inc Compuestos heterocíclicos fusionados como moduladores del canal de sodio.
TW201837023A (zh) 2011-07-01 2018-10-16 美商基利科學股份有限公司 作為離子通道調節劑之稠合雜環化合物
NO3175985T3 (sh) 2011-07-01 2018-04-28
JP7013213B2 (ja) * 2017-05-26 2022-01-31 日本化薬株式会社 ピラジン化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4921855A (en) * 1987-06-22 1990-05-01 Fujisawa Pharmaceutical Co., Ltd. New Histidyl amino acid derivatives, and pharmaceutical composition comprising the same
CA1328333C (en) * 1988-03-04 1994-04-05 Quirico Branca Amino acid derivatives
AU629867B2 (en) * 1988-11-17 1992-10-15 Imperial Chemical Industries Plc Triazolo (4,3a) pyrazine derivatives

Also Published As

Publication number Publication date
NO912537L (no) 1991-12-30
AU7927891A (en) 1992-01-02
EP0464572A3 (en) 1992-10-07
NZ238645A (en) 1993-07-27
IE912254A1 (en) 1992-01-01
ZA914808B (en) 1992-03-25
MX26375A (es) 1993-09-01
PT98123A (pt) 1992-03-31
FI913179A (fi) 1991-12-29
EP0464572A2 (de) 1992-01-08
CA2044564A1 (en) 1991-12-29
BR9102730A (pt) 1992-02-04
IS3725A7 (is) 1991-12-29
HU912097D0 (en) 1991-12-30
JPH04230380A (ja) 1992-08-19
FI913179A0 (fi) 1991-06-28
IL98576A0 (en) 1992-07-15
NO912537D0 (no) 1991-06-27
HUT61299A (en) 1992-12-28
KR920000762A (ko) 1992-01-29
AU642021B2 (en) 1993-10-07
MC2264A1 (fr) 1993-04-26

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