JPS55324A - Antithrombotic - Google Patents

Antithrombotic

Info

Publication number
JPS55324A
JPS55324A JP7296578A JP7296578A JPS55324A JP S55324 A JPS55324 A JP S55324A JP 7296578 A JP7296578 A JP 7296578A JP 7296578 A JP7296578 A JP 7296578A JP S55324 A JPS55324 A JP S55324A
Authority
JP
Japan
Prior art keywords
benzamide
antithrombotic
dithiobis
substituted
aralkylpiperazino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP7296578A
Other languages
Japanese (ja)
Other versions
JPS6141895B2 (en
Inventor
Koji Yamada
Kore Hashimoto
Masaori Naruse
Yu Murayama
Hideki Shinno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PAAMAKEMU ASIA KK
Permachem Asia Ltd
KH Neochem Co Ltd
Original Assignee
PAAMAKEMU ASIA KK
Kyowa Hakko Kogyo Co Ltd
Permachem Asia Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PAAMAKEMU ASIA KK, Kyowa Hakko Kogyo Co Ltd, Permachem Asia Ltd filed Critical PAAMAKEMU ASIA KK
Priority to JP7296578A priority Critical patent/JPS55324A/en
Priority to DE8282102632T priority patent/DE2967609D1/en
Priority to EP79101934A priority patent/EP0006227B1/en
Priority to DE7979101934T priority patent/DE2967337D1/en
Priority to EP82102632A priority patent/EP0062827B1/en
Priority to NO792002A priority patent/NO147876C/en
Priority to DK250779A priority patent/DK250779A/en
Priority to CA000329986A priority patent/CA1140549A/en
Publication of JPS55324A publication Critical patent/JPS55324A/en
Publication of JPS6141895B2 publication Critical patent/JPS6141895B2/ja
Priority to US07/016,473 priority patent/US4705805A/en
Granted legal-status Critical Current

Links

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE: An antithrombotic effective for circulation disturbance with low toxicity, comprising a 2, 2'-dithiobis[N-(un)substituted benzamide].
CONSTITUTION: An antithrombotic comprising a 2, 2'-dithiobis (N-substituted or unsubstituted benzamide) of the formula (R1 and R2 are amino, alkylamino, arylamino, aralkylamino, hydroxyalkylamino, alkylpiperazino, or aralkylpiperazino group), or its salt, e.g. 2, 2'-dithiobis (N-butyl-benzamide) or 2, 2'-dithio bis (N-benzyl benzamide), as a main ingredient is administered in a dose of 10W 500mg/adult orally or by injection. The antithrombotic has a great blood platelet antiagglutinating action.
COPYRIGHT: (C)1980,JPO&Japio
JP7296578A 1978-06-16 1978-06-16 Antithrombotic Granted JPS55324A (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
JP7296578A JPS55324A (en) 1978-06-16 1978-06-16 Antithrombotic
DE8282102632T DE2967609D1 (en) 1978-06-16 1979-06-13 Novel benzamide derivatives
EP79101934A EP0006227B1 (en) 1978-06-16 1979-06-13 Antithrombotic pharmaceutical preparation containing 2,2'-dithiobis benzamide derivatives and new 2,2'-dithiobis benzamide derivatives
DE7979101934T DE2967337D1 (en) 1978-06-16 1979-06-13 Antithrombotic pharmaceutical preparation containing 2,2'-dithiobis benzamide derivatives and new 2,2'-dithiobis benzamide derivatives
EP82102632A EP0062827B1 (en) 1978-06-16 1979-06-13 Novel benzamide derivatives
NO792002A NO147876C (en) 1978-06-16 1979-06-15 ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVITY 2,2`-DITIO-BIS (BENZAMIDE) DERIVATIVES OR SALTS THEREOF
DK250779A DK250779A (en) 1978-06-16 1979-06-15 PROCEDURE FOR THE PREPARATION OF 2,2-DITHIO-BIS- (BENZAMIDE) -DERIVATIVES OR SALTS OF SOME OF THE DERIVATIVES
CA000329986A CA1140549A (en) 1978-06-16 1979-06-18 Derivatives of 2,2'dithiobis-benzamide as antithrombotic agent
US07/016,473 US4705805A (en) 1978-06-16 1987-02-17 Antithrombotic agent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7296578A JPS55324A (en) 1978-06-16 1978-06-16 Antithrombotic

Publications (2)

Publication Number Publication Date
JPS55324A true JPS55324A (en) 1980-01-05
JPS6141895B2 JPS6141895B2 (en) 1986-09-18

Family

ID=13504591

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7296578A Granted JPS55324A (en) 1978-06-16 1978-06-16 Antithrombotic

Country Status (1)

Country Link
JP (1) JPS55324A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003534274A (en) * 2000-05-19 2003-11-18 アルコン，インコーポレイテッド Composition comprising benzamide disulfide derivative for treating allergic disease

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003534274A (en) * 2000-05-19 2003-11-18 アルコン，インコーポレイテッド Composition comprising benzamide disulfide derivative for treating allergic disease

Also Published As

Publication number Publication date
JPS6141895B2 (en) 1986-09-18

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