JPS5331674A - 5-fluorouracil derivatives and their preparation - Google Patents
5-fluorouracil derivatives and their preparationInfo
- Publication number
- JPS5331674A JPS5331674A JP10492876A JP10492876A JPS5331674A JP S5331674 A JPS5331674 A JP S5331674A JP 10492876 A JP10492876 A JP 10492876A JP 10492876 A JP10492876 A JP 10492876A JP S5331674 A JPS5331674 A JP S5331674A
- Authority
- JP
- Japan
- Prior art keywords
- preparation
- fluorouracil derivatives
- fluorouracil
- derivatives
- ethoxycarbonyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/553—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE: 5-Fluorouracil derivatives I(X is O or S; R is 1 - 15C alkyl, 4 8C cycloalkyl or aryl), e.g. N1 -ethoxycarbonyl-5-fluorouracil.
COPYRIGHT: (C)1978,JPO&Japio
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP51104928A JPS6024789B2 (en) | 1976-09-03 | 1976-09-03 | 5-Fluorouracil derivative compound |
GB7736781A GB1542053A (en) | 1976-09-03 | 1977-09-02 | 5-fluorouracil derivatives |
FR7726853A FR2363562A1 (en) | 1976-09-03 | 1977-09-05 | NEW DERIVATIVES OF 5-FLUOROURACIL, USEFUL IN PARTICULAR AS ANTI-CANCER AGENTS AND THEIR PREPARATION PROCESS |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP51104928A JPS6024789B2 (en) | 1976-09-03 | 1976-09-03 | 5-Fluorouracil derivative compound |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5331674A true JPS5331674A (en) | 1978-03-25 |
JPS6024789B2 JPS6024789B2 (en) | 1985-06-14 |
Family
ID=14393750
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP51104928A Expired JPS6024789B2 (en) | 1976-09-03 | 1976-09-03 | 5-Fluorouracil derivative compound |
Country Status (3)
Country | Link |
---|---|
JP (1) | JPS6024789B2 (en) |
FR (1) | FR2363562A1 (en) |
GB (1) | GB1542053A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5587721A (en) * | 1978-12-26 | 1980-07-02 | Ono Pharmaceut Co Ltd | Anti-tumor agent |
JP2018522860A (en) * | 2015-06-24 | 2018-08-16 | ケンブリッジ・エンタープライズ・リミテッドCambridge Enterprise Limited | Amorphous metal-organic structure |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3165782D1 (en) * | 1980-10-01 | 1984-10-04 | Beecham Group Plc | 5-fluoro uracil derivatives |
DK197486A (en) * | 1986-04-30 | 1987-10-31 | Ferring Farma Lab | 5-FLUORURACIL PRODUCT |
-
1976
- 1976-09-03 JP JP51104928A patent/JPS6024789B2/en not_active Expired
-
1977
- 1977-09-02 GB GB7736781A patent/GB1542053A/en not_active Expired
- 1977-09-05 FR FR7726853A patent/FR2363562A1/en active Granted
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5587721A (en) * | 1978-12-26 | 1980-07-02 | Ono Pharmaceut Co Ltd | Anti-tumor agent |
JPS6227047B2 (en) * | 1978-12-26 | 1987-06-12 | Setsuo Fujii | |
JP2018522860A (en) * | 2015-06-24 | 2018-08-16 | ケンブリッジ・エンタープライズ・リミテッドCambridge Enterprise Limited | Amorphous metal-organic structure |
Also Published As
Publication number | Publication date |
---|---|
GB1542053A (en) | 1979-03-14 |
FR2363562A1 (en) | 1978-03-31 |
FR2363562B1 (en) | 1981-07-24 |
JPS6024789B2 (en) | 1985-06-14 |
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