WO2024139013A1 - Multifunctional automatic analyzer - Google Patents

Abstract

A multifunctional automatic analyzer, comprising a support assembly, a pipetting and cup moving assembly, a consumable assembly, a cleaning assembly, a liquid path assembly, and a detection module. The support assembly comprises a bottom plate, a vertical plate, and a mounting plate. The vertical plate is vertically mounted on the bottom plate, the mounting plate and the vertical plate are assembled together, and the mounting plate is parallel to the bottom plate; the pipetting and cup moving assembly is slidably mounted on the vertical plate; a part of the consumable assembly is slidably mounted on the bottom plate, the other part of the consumable assembly is slidably mounted on the mounting plate, and a reaction cup, a sampling head, a reagent, and a sample are stored in the consumable assembly; the pipetting and cup moving assembly is located at the top of the consumable assembly; the cleaning assembly is slidably mounted at the top of the mounting plate, and the liquid path assembly is mounted at the top of the mounting plate; and the detection module is detachably connected to the support assembly.

Description

A multifunctional automated analyzer

This application claims the priority of the Chinese patent application filed with the China Patent Office on December 29, 2022, with application number 202211716882.2 and invention name “A Multifunctional Automated Analyzer”, the entire contents of which are incorporated by reference in this application.

Technical Field

The present invention relates to the technical field related to automated analyzers, and more precisely to a multifunctional automated analyzer.

Background technique

Automated analyzers are widely used in scientific research, medical testing, teaching and other fields. According to different functions, they can be divided into biochemical automatic analyzers, immune automatic analyzers, protein automatic analyzers, etc. Automated analyzers with different functions use different detection modules.

The automated analyzer uses its own automation to extract, inject, and extract samples and reagents, and uses the installed detection device to detect the reactants of the samples and reagents. Finally, the computer analyzes the test results to obtain the analysis results. Compared with the traditional manual operation scheme, the automated analyzer has higher detection efficiency and lower error rate.

Most of the automated analyzers in the prior art have a single function, and one automated analyzer can only realize one detection function. At the same time, the volume of the automated analyzer is generally large, and the structural components are also relatively complex. In summary, the field needs to improve the automated analyzer to enhance the diversity and openness of its detection functions, while reducing the volume and improving portability.

Summary of the invention

In view of this, an object of the present invention is to provide a multifunctional automated analyzer which adopts a modular design and can realize different detection functions by replacing detection modules. The overall structure is compact, the volume is smaller, and the transportation is convenient.

In order to achieve the above-mentioned object, the present invention provides a multifunctional automated analyzer, comprising a support assembly, a liquid transfer cup assembly, a consumable assembly, a cleaning assembly, a liquid circuit assembly and a detection module; the support assembly comprises a bottom plate, a vertical plate and a mounting plate, the vertical plate is vertically mounted on the bottom plate, the mounting plate is combined with the vertical plate and mounted, and the mounting plate is parallel to the bottom plate; the liquid transfer cup assembly is slidably mounted on the vertical plate, and the liquid transfer cup assembly has two degrees of freedom in the horizontal and vertical directions; the consumable assembly is partially slidably mounted on the bottom plate, The other part is slidably mounted on the mounting plate, and the consumable assembly stores reaction cups, sampling heads, reagents and samples; the pipetting cup assembly is located on the top of the consumable assembly; the cleaning assembly is slidably mounted on the top of the mounting plate, and the liquid path assembly is mounted on the top of the mounting plate; the detection module is detachably connected to the bracket assembly.

Preferably, the detection module includes one or both of a biochemical detection module and an immune detection module.

Preferably, the biochemical detection module is mounted on the bottom plate and arranged on the side of the consumables assembly, and the biochemical detection module includes a sample loading position, a detection position and a cleaning position.

Preferably, the immune detection module is mounted on the bottom plate, and the immune detection module includes a shutter light-shielding structure.

Preferably, the pipetting and cup transfer assembly includes a transverse drive assembly, a movable mounting bracket, a longitudinal drive assembly, and a pipette and manipulator assembly; the transverse drive assembly is installed in combination with the vertical plate, the movable mounting bracket is installed in combination with the transverse drive assembly, and the movable mounting bracket is driven by the transverse drive assembly to move in a direction parallel to the horizontal plane; the longitudinal drive assembly is installed on the movable mounting bracket, the pipette and manipulator assembly is installed in combination with the longitudinal drive assembly, and the pipette and manipulator assembly is driven by the longitudinal drive assembly to move in a direction perpendicular to the horizontal plane.

Preferably, the consumables assembly includes a lower layer assembly, a reaction cup storage area, a sampling head storage area and a magnetic attraction area, and the lower layer assembly accommodates reagents and samples; the reaction cup storage area, the sampling head storage area and the magnetic attraction area can be slidably mounted on the mounting plate, and the lower layer assembly can be slidably mounted on the bottom plate.

Preferably, the consumable assembly includes a consumable drive assembly, the consumable drive assembly is mounted on the bottom plate, and the lower layer assembly, the reaction cup storage area and the sampling head storage area are all transmission-connected to the consumable drive assembly.

Preferably, the cleaning assembly includes a cleaning needle group and a cleaning module, the cleaning needle group is located on the top of the cleaning module, the cleaning module is connected to the liquid circuit assembly, the cleaning module moves synchronously with the reaction cup storage area and the sampling head storage area, and the cleaning needle group is installed in combination with the vertical plate.

Preferably, the lower layer component includes a sample storage area and a reagent storage area, the sample storage area The area is arranged adjacent to the detection module, and the reagent storage area is located on a side of the sample storage area away from the detection module.

Preferably, the bottom of the vertical plate has a penetration area, and the consumable component and the cleaning component can slide through the penetration area.

Compared with the prior art, the advantages of the multifunctional automated analyzer disclosed in the present invention are: the multifunctional automated analyzer adopts a modular design, and different detection functions can be realized by replacing the detection module, and the diversity and openness of the detection functions are better; the multifunctional automated analyzer has a compact structure, a smaller size, and is easy to carry.

BRIEF DESCRIPTION OF THE DRAWINGS

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

FIG1 is a perspective view of a multifunctional automated analyzer of the present invention;

FIG. 2 is a back-axial view of a multifunctional automated analyzer of the present invention;

FIG3 is a front isometric view of a first variant of a multifunctional automated analyzer of the present invention;

FIG4 is a back-axial view of a first variant of a multifunctional automated analyzer of the present invention;

FIG5 is a top view of a first variant of a multifunctional automated analyzer of the present invention;

FIG6 is a left view of a first variant of a multifunctional automated analyzer of the present invention;

FIG. 7 is an isometric view of a second variant of a multifunctional automated analyzer of the present invention;

FIG8 is a dorsal axial view of a second variant of a multifunctional automated analyzer of the present invention;

FIG. 9 is a top view of a second variant of a multifunctional automated analyzer according to the present invention. picture;

FIG. 10 is a left view of a second variant of a multifunctional automated analyzer according to the present invention.

Detailed ways

The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

As shown in Figures 1 and 2, a multifunctional automated analyzer of the present application includes a support assembly 1, a liquid transfer cup assembly 2, a consumable assembly 3, a cleaning assembly 4, a liquid circuit assembly 5 and a detection module 6. The support assembly 1 includes a base plate 11, a vertical plate 12 and a mounting plate 13, the vertical plate 12 is vertically mounted on the base plate 11, the mounting plate 13 is combined with the vertical plate 12 and mounted, and the mounting plate 13 is parallel to the base plate 11. The liquid transfer cup assembly 2 can be slidably mounted on the vertical plate 12, and the liquid transfer cup assembly 2 has two degrees of freedom in the horizontal and vertical directions. Part of the consumable assembly 3 can be slidably mounted on the base plate 10, and the other part can be slidably mounted on the mounting plate 13, and the consumable assembly 3 stores the reaction cup, the sampling head, the reagent and the sample. The liquid transfer cup assembly 2 is located at the top of the consumable assembly 3. The cleaning assembly 4 can be slidably mounted on the top of the mounting plate 13, and the liquid circuit assembly 5 is mounted on the top of the mounting plate 13. The detection module 6 is detachably connected to the support assembly 1. The detection module includes one or both of a biochemical detection module 61 and an immune detection module 62 .

The multifunctional automated analyzer adopts a modular design, and different detection functions can be realized by replacing the detection module, and the diversity and openness of the detection functions are better. The multifunctional automated analyzer has a compact structure, a smaller volume, and is convenient to carry.

Specifically, the liquid transfer and cup transfer assembly 2 includes a transverse drive assembly 21, a mobile mounting bracket 22, a longitudinal drive assembly 23, and a pipette and manipulator assembly 24. The transverse drive assembly 21 is installed in combination with the vertical plate 12, and the mobile mounting bracket 22 is installed in combination with the transverse drive assembly 21. The mobile mounting bracket 22 is driven by the transverse drive assembly 21 to move in a direction parallel to the horizontal plane. The longitudinal drive assembly 23 is installed on the mobile mounting bracket 22, and the pipette and manipulator assembly 24 is installed in combination with the longitudinal drive assembly 23. The pipette and manipulator assembly 24 is driven by the longitudinal drive assembly 23 to move in a direction perpendicular to the horizontal plane. The pipette can absorb the sampling head, and the pipette can inject the required liquid into the reaction cup and the colorimetric cup through the sampling head, and the manipulator can grab and place the reaction cup.

The consumable component 3 includes a consumable drive component 30, a lower component 31, a reaction cup storage area 32, a sampling head storage area 33 and a magnetic attraction area 34. The lower component 31 contains reagents and samples; the reaction cup storage area 32, the sampling head storage area 33 and the magnetic attraction area 34 are slidably mounted on the mounting plate 12, and the magnetic attraction area 34 is located on the side of the reaction cup storage area 32 away from the sampling head storage area 33. The lower component 31 is slidably mounted on the bottom plate 11, the consumable drive component 30 is mounted on the bottom plate 11, and the lower component 31, the reaction cup storage area 32 and the sampling head storage area 33 are all connected to the consumable drive component 30 in a transmission manner. The reaction cups all have magnets, which can be adsorbed and set at the magnetic attraction area 34 to wait for cleaning.

Further, referring to FIG. 6 , the bottom of the vertical plate 12 has a penetration area 120 , and both the consumable component 3 and the cleaning component 4 can slide through the penetration area 120 .

The biochemical detection module 61 is mounted on the bottom plate 10 and is arranged on the side of the consumable component 3. The biochemical detection module 61 includes a sample loading position, a detection position and a cleaning position. The immunodetection module 62 is mounted on the bottom plate 10 and is arranged on the side of the biochemical detection module 61. The immunodetection module 62 includes a shutter light shielding structure.

The multifunctional automated analyzer has a biochemical detection module 61 and an immune detection module 62, which can realize two detection functions without interfering with each other, with high detection accuracy and a compact overall structure.

3 to 6 , which are a first variant of the multifunctional automated analyzer, the difference being that the detection module 6 only includes a biochemical detection module 61 .

The cleaning assembly 4 includes a cleaning needle group 41 and a cleaning module 42. The cleaning needle group 41 is located at the top of the cleaning module 42. The cleaning module 42 is connected to the liquid circuit assembly 5. The cleaning module 42 moves synchronously with the reaction cup storage area 32 and the sampling head storage area 33. The cleaning needle group 41 is installed in combination with the vertical plate 12. The liquid transfer cup assembly 2 can grab the reaction cup and send it to the cleaning module 42 through a manipulator. The cleaning module 42 can be cleaned when it reaches the bottom of the cleaning needle group 41.

7 to 10 , which are a second variant of the multifunctional automated analyzer, the difference being that the detection module 6 only includes an immune detection module 62 .

The lower component 31 includes a sample storage area 311 and a reagent storage area 312 . The sample storage area 311 is disposed adjacent to the detection module 6 , and the reagent storage area 312 is located on a side of the sample storage area 311 away from the detection module 6 .

The above description of the disclosed embodiments enables those skilled in the art to implement or use the present invention. Various modifications to these embodiments will be apparent to those skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the present invention. Therefore, the present invention will not be limited to the embodiments shown herein, but rather to the widest scope consistent with the principles and novel features disclosed herein.

Claims (10)

1. A multifunctional automated analyzer, characterized in that it includes a bracket assembly, a pipetting cup assembly, a consumable assembly, a cleaning assembly, a liquid circuit assembly and a detection module; the bracket assembly includes a base plate, a vertical plate and a mounting plate, the vertical plate is vertically mounted on the base plate, the mounting plate is mounted in combination with the vertical plate, and the mounting plate is parallel to the base plate; the pipetting cup assembly is slidably mounted on the vertical plate, and the pipetting cup assembly has freedom in both horizontal and vertical directions; part of the consumable assembly is slidably mounted on the base plate, and the other part is slidably mounted on the mounting plate, and the consumable assembly stores reaction cups, sampling heads, reagents and samples; the pipetting cup assembly is located at the top of the consumable assembly; the cleaning assembly is slidably mounted on the top of the mounting plate, and the liquid circuit assembly is mounted on the top of the mounting plate; the detection module is detachably connected to the bracket assembly.
2. The multifunctional automated analyzer according to claim 1, characterized in that the detection module comprises one or both of a biochemical detection module and an immune detection module.
3. The multifunctional automated analyzer as described in claim 2 is characterized in that the biochemical detection module is installed on the base plate, and the biochemical detection module is arranged on the side of the consumable component, and the biochemical detection module includes a sample loading position, a detection position and a cleaning position.
4. The multifunctional automated analyzer as described in claim 2 is characterized in that the immunodetection module is installed on the base plate, and the immunodetection module includes a shutter shading structure.
5. The multifunctional automated analyzer as described in claim 1 is characterized in that the pipetting and cup transfer assembly includes a transverse drive assembly, a movable mounting bracket, a longitudinal drive assembly, and a pipette and manipulator assembly; the transverse drive assembly is installed in combination with the vertical plate, the movable mounting bracket is installed in combination with the transverse drive assembly, and the movable mounting bracket is driven by the transverse drive assembly to move in a direction parallel to the horizontal plane; the longitudinal drive assembly is installed on the movable mounting bracket, the pipette and manipulator assembly is installed in combination with the longitudinal drive assembly, and the pipette and manipulator assembly is driven by the longitudinal drive assembly to move in a direction perpendicular to the horizontal plane.
6. The multifunctional automated analyzer as described in claim 1 is characterized in that the consumable component includes a lower layer component, a reaction cup storage area, a sampling head storage area and a magnetic attraction area, and the lower layer component contains reagents and samples; the reaction cup storage area, the sampling head storage area and the magnetic attraction area can be slidably installed on the mounting plate, and the lower layer component can be slidably installed on the bottom plate.
7. The multifunctional automated analyzer as described in claim 6 is characterized in that the consumable assembly includes a consumable drive assembly, the consumable drive assembly is installed on the bottom plate, and the lower layer assembly, the reaction cup storage area and the sampling head storage area are all transmission-connected to the consumable drive assembly.
8. The multifunctional automated analyzer as described in claim 6 is characterized in that the cleaning assembly includes a cleaning needle group and a cleaning module, the cleaning needle group is located on the top of the cleaning module, the cleaning module is connected to the liquid circuit assembly, the cleaning module moves synchronously with the reaction cup storage area and the sampling head storage area, and the cleaning needle group is installed in combination with the vertical plate.
9. The multifunctional automated analyzer as described in claim 6 is characterized in that the lower layer component includes a sample storage area and a reagent storage area, the sample storage area is arranged adjacent to the detection module, and the reagent storage area is located on a side of the sample storage area away from the detection module.
10. The multifunctional automated analyzer as described in claim 1 is characterized in that the bottom of the vertical plate has a penetration area, and the consumable component and the cleaning component can slide through the penetration area.