WO2023160623A1 - 控制方法、多通量离心平台及计算机可读存储介质 - Google Patents

控制方法、多通量离心平台及计算机可读存储介质 Download PDF

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Publication number
WO2023160623A1
WO2023160623A1 PCT/CN2023/077942 CN2023077942W WO2023160623A1 WO 2023160623 A1 WO2023160623 A1 WO 2023160623A1 CN 2023077942 W CN2023077942 W CN 2023077942W WO 2023160623 A1 WO2023160623 A1 WO 2023160623A1
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WO
WIPO (PCT)
Prior art keywords
card
detection
strategy
trim
tray
Prior art date
Application number
PCT/CN2023/077942
Other languages
English (en)
French (fr)
Inventor
皮世威
李国�
赵志翔
Original Assignee
深圳市理邦精密仪器股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 深圳市理邦精密仪器股份有限公司 filed Critical 深圳市理邦精密仪器股份有限公司
Publication of WO2023160623A1 publication Critical patent/WO2023160623A1/zh

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B9/00—Drives specially designed for centrifuges; Arrangement or disposition of transmission gearing; Suspending or balancing rotary bowls
    • B04B9/14—Balancing rotary bowls ; Schrappers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/36—Apparatus for enzymology or microbiology including condition or time responsive control, e.g. automatically controlled fermentors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H40/00—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices
    • G16H40/60—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices
    • G16H40/63—ICT specially adapted for the management or administration of healthcare resources or facilities; ICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation

Definitions

  • the application relates to the technical field of molecular detection, in particular to a control method, a multi-throughput centrifugal platform and a computer-readable storage medium.
  • Molecular diagnostic technology refers to the diagnostic technology that uses nucleic acid or protein as a biomarker for clinical detection, which provides information and decision-making basis for the prediction, diagnosis, prevention, treatment and outcome of diseases.
  • the detection card When the molecular diagnostic equipment detects the detection card, the detection card needs to be centrifuged in advance. In some cases, the number of detection cards is not enough to distribute evenly on the card tray, which will cause noise during centrifugation.
  • One aspect of the present application provides a control method based on a multi-throughput centrifugal platform, including:
  • the card holder is controlled to rotate according to the strategy, and the card position of the card holder is revealed at the bayonet drop.
  • the application also provides a multi-throughput centrifugal platform, including:
  • Obtaining module used to obtain the number of detection cards
  • a determination module configured to determine the card tray rotation strategy of the multi-throughput centrifugal platform corresponding to the number of detection cards
  • the control module is used to control the rotation of the card holder according to the strategy, and reveal the card position of the card holder at the bayonet drop.
  • the present application also provides a computer-readable storage medium, on which a computer program is stored, and when the computer program is executed by a processor, the method as described in any one of the above is implemented.
  • FIG. 1 is a schematic diagram of a three-dimensional structure of a molecular diagnostic device in an embodiment of the present application
  • Fig. 2 is an exploded exploded view of the molecular diagnostic device in Fig. 1;
  • Fig. 3 is a schematic diagram of the explosion of the pressure plate in Fig. 2;
  • Fig. 4 and Fig. 5 are the structural schematic diagrams of different viewing angles of the first casing in Fig. 3 respectively;
  • Fig. 6 is a structural schematic diagram of the pressure plate in Fig. 3;
  • Fig. 7 is a schematic diagram of the connection structure between the rack and the pressure plate in Fig. 2;
  • Fig. 8 is a schematic structural view of the consignment assembly in Fig. 2;
  • Figure 9 is a schematic structural view of the consignment in Figure 8.
  • Fig. 10 and Fig. 11 are schematic structural diagrams of different viewing angles under the cooperation of the pressure plate and the consignment assembly in Fig. 2;
  • Fig. 12 is an exploded view of the test seat of the test card in Fig. 2;
  • Fig. 13 is an exploded view of the support seat in Fig. 12;
  • Fig. 14 is a schematic structural view of the main body of the support seat in Fig. 13;
  • Fig. 15 is a schematic structural view of the photodetector in Fig. 13;
  • Fig. 16 is a schematic structural view of the sample chamber assembly in Fig. 13;
  • Fig. 17 is a schematic structural view of the optical generator in Fig. 12;
  • Fig. 18 is a schematic structural diagram of a detection card in an embodiment of the present application.
  • Fig. 19 is a sectional view of the detection card along line L-L in Fig. 18;
  • Fig. 20 is a schematic diagram of the three-dimensional structure of the detection card in Fig. 18;
  • Fig. 21 is a schematic diagram of the process of using the detection card in Fig. 20;
  • Fig. 22 is a flowchart of a control method based on a multi-throughput centrifugal platform in an embodiment of the present application
  • Fig. 23 is a flowchart of a control method based on a multi-throughput centrifugal platform in another embodiment of the present application.
  • Fig. 24 is a flowchart of a control method based on a multi-throughput centrifugal platform in another embodiment of the present application.
  • Fig. 25 is a flowchart of a control method based on a multi-throughput centrifugal platform in another embodiment of the present application.
  • Fig. 26 is a schematic structural diagram of a multi-throughput centrifugal platform in an embodiment of the present application.
  • Fig. 27 is a schematic diagram of a computer-readable storage medium according to an embodiment of the present application.
  • Molecular diagnostic technology refers to the diagnostic technology that uses nucleic acid or protein as a biomarker for clinical detection, which provides information and decision-making basis for the prediction, diagnosis, prevention, treatment and outcome of diseases. Especially in the face of various sudden infectious diseases, the most cost-effective measure is rapid and accurate molecular diagnosis.
  • FIG. 1 is a three-dimensional schematic diagram of a molecular diagnostic device 100 in an embodiment of the present application
  • FIG. 2 is an exploded exploded view of the molecular diagnostic device 100 in FIG. 1
  • the molecular diagnostic equipment 100 may include a frame 10 , a detection card delivery base 20 mounted on the frame 10 , a detection card detection base 30 mounted on the frame 10 , and a control circuit board 40 mounted on the frame 10 .
  • the test card delivery seat 20 can be used to place the test card.
  • the test card transport seat 20 can slide relative to the frame 10 , so that the test card transport seat 20 consigns the test card and consigns it to the test card detection seat 30 .
  • the detection card detection seat 30 is used to generate excitation light to detect the detection card and form a detection signal.
  • the control circuit board 40 can be used to control the sliding of the test card delivery seat 20 on the frame 10, and control the test card detection seat 30 to detect the test card, receive the detection signal and process the detection signal to form diagnostic data.
  • the molecular diagnostic device 100 may also include input devices such as a display, a keyboard, and a code scanning device 14 (shown in FIG.
  • the control circuit board 40 inputs control instructions to realize the control of the detection card delivery seat 20 and/or the detection card detection seat 30 by the molecular diagnostic equipment 100 through the control circuit board 40
  • the frame 10 may include a frame body 11 , a first driving assembly 12 installed on the frame body 11 , and a lead screw 13 installed on the frame body 11 .
  • the frame main body 11 is used for installing structures such as the detection card delivery seat 20 , the test card detection seat 30 and the control circuit board 40 .
  • the first drive assembly 12 is used for electrical connection with the control circuit board 40 to accept the control of the control circuit board 40 .
  • the first drive assembly 12 drives the lead screw 13 to rotate under the control of the control circuit board 40 .
  • the lead screw 13 is rotatably connected with the detection card delivery base 20, so that under the drive of the first drive assembly 12, the detection card delivery base 20 slides relative to the frame main body 11 in the extension direction of the lead screw 13, so as to realize the detection card delivery. consignment.
  • the frame body 11 as a whole can be a frame structure.
  • the inside of the frame main body 11 can be used to install the test card delivery seat 20 and the test card detection seat 30 , and the test card delivery seat 20 is located above the test card detection seat 30 .
  • the installation positions of the test card delivery seat 20 and the test card detection seat 30 on the main body 11 of the rack can be other, and details will not be described here.
  • orientations such as “upper”, “lower”, “front”, “rear”, “left”, “right”, “top”, “bottom”, “upper” and “lower” may be used for description. It should be understood that the terms “central”, “longitudinal”, “transverse”, “length”, “width”, “thickness”, “upper”, “lower”, “front”, “rear”, “left”, “right”, “vertical” in this document.
  • the orientation or positional relationship indicated by “horizontal”, “top”, “bottom”, “inner”, “outer”, “clockwise”, “counterclockwise”, “axial”, “radial” and “circumferential” are based on the orientation shown in the drawings Or positional relationship is only for the convenience of describing the present application and simplifying the description, but does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of the present application.
  • the frame main body 11 is provided with a first guide rail 111 .
  • the first guide rail 111 can be used for installing the test card delivery base 20 , so that the test card delivery base 20 slides on the first guide rail 111 and slides in the extending direction of the first guide rail 111 .
  • the extending direction of the first guide rail 111 may be a vertical direction.
  • first and second herein are used for description purposes only, and cannot be understood as indicating or implying relative importance or implicitly specifying the quantity of indicated technical features.
  • a feature defined as “first” and “second” may explicitly or implicitly include one or more of said features.
  • the lead screw 13 can be installed on the frame main body 11 . Driven by the first drive assembly 12 , the lead screw 13 can push the test card delivery base 20 to slide on the frame body 11 such as the first guide rail 111 , so that the test card delivery base 20 can consign the test card.
  • the extending direction of the lead screw 13 may be the same as the extending direction of the first guide rail 111 .
  • the frame 10 such as the frame body 11 , is provided with a code scanning device 14 electrically connected to the control circuit board 40 .
  • the code scanning device 14 can be used to scan the image of the information identification on the detection card, such as a two-dimensional code, a bar code, etc., and transmit the image to the control circuit board 40 .
  • Control circuit board 40 Recognize the image and obtain the relevant information of the test card.
  • the code scanning device 14 can be arranged on the path where the detection card delivery seat 20 slides relative to the frame 10, so that when the detection card is placed on the detection card delivery seat 20, the information on the detection card is imaged by the scanning code device 14. scanning.
  • the test card delivery base 20 may include a pressing plate 50 and a shipping component 60 mounted on the frame 10 such as the first guide rail 111 .
  • the shipping component 60 is used for placing the detection card.
  • the pressure plate 50 is threadedly connected with the lead screw 13, so as to slide on the first guide rail 111 under the action of the first drive assembly 12, and then drive the consignment assembly 60 to slide on the first guide rail 111, and the consignment assembly 60 can consign the detection card And consigned to the detection card detection seat 30.
  • FIG. 3 is an exploded view of the pressure plate 50 in FIG. 2 .
  • the pressure plate 50 may include a first housing 51 installed on the frame 10 such as the lead screw 13, an electromagnet 52 arranged on the side of the first housing 51 facing the detection card detection seat 30, and used for checking the shipping assembly 60.
  • the pressing part 53 for fixing the detection card, the first heating part 54 and the second heating part 55 arranged on the first casing 51 are installed on the first casing 51 and are connected with the electromagnetic part 52 and the first heating part respectively.
  • the first circuit board 56 electrically connected to the element 54 and the second heating element 55, the second casing 57 covered on the side of the first casing 51 away from the electromagnetic element 52, and the first casing 51 and installed on the machine
  • the rack 10 is, for example, the first slide rail 58 on the first guide rail 111 .
  • the first shell 51 and the second shell 57 are fastened together to form the main body of the pressing plate.
  • the first circuit board 56 may be electrically connected to the control circuit board 40 .
  • the electromagnetic component 52 can generate a magnetic force under the control of the control circuit board 40 to attract the pressing component 53 to the first casing 51 .
  • the electromagnetic part 52 can eliminate the magnetic force under the control of the control circuit board 40 , so as to avoid adsorption to the pressing part 53 .
  • the first heating element 54 and the second heating element 55 can heat the detection card under the control of the control circuit board 40 .
  • the first slide rail 58 can slide on the rack 10 such as the first guide rail 111 .
  • the first housing 51 is connected to the frame 10 such as the lead screw 13 so as to slide in the extending direction of the first guide rail 111 under the rotation of the lead screw 13 .
  • FIG. 4 and FIG. 5 are structural schematic diagrams of the first housing 51 in FIG. 3 from different perspectives.
  • the first housing 51 can be made of hard materials such as plastic, metal and the like.
  • the first housing 51 may be in the form of a plate, and of course it may also be in other shapes, which will not be repeated here.
  • the first case 51 may include a case body 511 .
  • a receiving groove 512 is provided in a middle portion of the housing main body 511 facing the second housing 57 for receiving the first circuit board 56 .
  • the cross section of the receiving groove 512 can be circular or other shapes.
  • the casing main body 511 may have a locking hole 513 around the receiving groove 512 for installing the first heating element 54 .
  • the locking holes 513 may be evenly distributed around the receiving groove 512 .
  • the number of locking holes 513 can also be one of 2, 3, 4, 5, 6.... In one embodiment, the number of locking holes 513 can be specifically six. In one embodiment.
  • the locking hole 513 is shaped as a segment of a ring structure.
  • the shell body 511 is provided with a gap 514 to make way for the shipping assembly 60 .
  • the notch 514 extends from an edge of the casing body 511 near the code scanning device 14 to the inside. In one embodiment, the notch 514 is located between two adjacent locking holes 513 .
  • the housing body 511 is provided with a threaded portion 515 near the lead screw 13 .
  • the threaded portion 515 can be sleeved on the lead screw 13 .
  • the threaded portion 515 is provided with an internal thread that cooperates with the external thread of the lead screw 13 , so that when the lead screw 13 rotates, the housing body 511 moves in the extending direction of the lead screw 13 .
  • the middle part of the surface of the casing body 511 away from the second casing 57 can be used for connecting the electromagnetic element 52 , the pressing element 53 and the second heating element 55 .
  • a plurality of accommodating slots 516 are evenly distributed on the middle circumference of the housing body 511 on the side away from the second housing 57 for installing the electromagnetic component 52 .
  • the number of accommodating grooves 516 may be multiple, and the specific number may be one of 2, 3, 4, 5, 6 and so on. In one embodiment, the number of accommodating grooves 516 may be two.
  • the electromagnetic component 52 can be energized to generate a magnetic force, and then the pressing component 53 can be adsorbed and fixed.
  • the electromagnetic component 52 is electrically connected to the first circuit board 56 , and the number can be two, and one electromagnetic component 52 can be installed in a receiving slot 516 .
  • the electromagnetic component 52 can be fixed on the housing main body 511 by screwing, clipping, inserting, welding, bonding and other connection methods.
  • the pressing member 53 can be made of a hard material such as metal, specifically, it can be made of metal such as iron that is attracted by the electromagnet under the magnetic force.
  • each pressing member 53 can also be made of hard materials such as plastic, metal and the like.
  • the first heating element 54 is installed on the side of the first casing 51 such as the casing main body 511 close to the second casing 57 .
  • Heating elements such as heating resistors can be arranged inside the first heating element 54 .
  • the number of the first heating elements 54 may be multiple, and the specific number may be one of 2, 3, 4, 5, 6 and so on. In an embodiment, the number of the first heating elements 54 may be the same as the number of the locking holes 513 , which may be six.
  • the first heating element 54 can be placed in the first housing 51 such as the engaging hole 513 , and be engaged with the first housing 51 such as the housing main body 511 to realize the installation of the first heating element 54 on the first housing 51 .
  • the first heating element 54 is electrically connected to the first circuit board 56 to realize the control of the heat-generating components inside the first heating element 54 .
  • the second heating element 55 is installed on the side of the first casing 51 such as the casing main body 511 away from the second casing 57 .
  • the second heating element 55 may be in an annular structure as a whole.
  • the second heating element 55 can be made of a heat-conductive hard material such as metal, and a heating element such as a heating resistor can be arranged inside.
  • the second heating element 55 is mounted on a side of the housing main body 511 away from the second housing 57 .
  • the second heating element 55 can be fixed on the relief groove 517 by screwing, inserting, buckling and other connection methods.
  • the heating element inside the second heating element 55 is electrically connected to the first circuit board 56 to realize the control of the heating element inside the second heating element 55 .
  • the first circuit board 56 may have a ring structure as a whole. Electronic components such as resistors, capacitors, and inductors are arranged on the first circuit board 56 .
  • the first circuit board 56 is installed in the receiving groove 512 of the casing body 511 .
  • the first circuit board 56 can be electrically connected with the heating element in the first heating element 54, the heating element in the second heating element 55, and the electromagnetic element 52, so that the heating element in the first heating element 54, the second heating element The heating device in the 55 and the electromagnetic part 52 are controlled respectively.
  • FIG. 6 is a schematic structural diagram of the resisting plate 50 in FIG. 3 .
  • the second housing 57 can include a cover body 571 that can be buckled with the first housing 51 , such as the housing main body 511 .
  • the cover main body 571 can be connected and fixed with the first housing 51 such as the housing main body 511 by screwing, inserting, buckling, welding, bonding and other connection methods, which will not be repeated here.
  • the cover body 571 can be made of hard materials such as plastic, metal and the like.
  • the cover main body 571 is provided with a through hole 572 .
  • the through hole 572 can be disposed opposite to the receiving slot 512 to give way to the first circuit board 56 so that the first circuit board 56 is exposed outside.
  • the through hole 572 may be omitted, and the cover body 571 completely covers the first casing 51 such as the casing body 511 .
  • the cover body 571 is provided with a notch 573 .
  • the notch 573 extends inwardly from the edge of the cover body 571 to communicate with the through hole 572 .
  • the notch 573 is arranged on the cover body 571 at a position opposite to the notch 514, so that when the cover body 571 is fastened with the housing body 511, the notch 573 communicates with the notch 514 to give way to the consignment component 60, so that the consignment component 60 It can slide in the notch 573 and the notch 514 .
  • the cover main body 571 is provided with a hanging ear 574 on a side away from the first housing 51 to connect with the shipping assembly 60 .
  • the hanging ear 574 is connected and fixed on the cover main body 571 by screwing, inserting, buckling, welding, bonding and other connection methods.
  • the first sliding rail 58 is disposed on the first casing 51 to realize the sliding connection between the first casing 51 and the frame 10 such as the first guide rail 111 .
  • FIG. 7 is a schematic diagram of the connection structure between the frame 10 and the pressing plate 50 in FIG. 2 .
  • the pressing plate 50 is installed on the frame 10 .
  • the first slide rail 58 is installed on the first guide rail 111 on the frame main body 11 .
  • the threaded portion 515 is threaded with the lead screw 13 .
  • the lead screw 13 is driven to move synchronously, and then the lead screw 13 and the pressure plate 50 are relatively rotated, so that the first slide rail 58 of the pressure plate 50 can slide on the first guide rail 111 , realizing the positional movement of the pressing plate 50 , specifically realizing the positional movement of the pressing plate 50 in the vertical direction.
  • FIG. 8 is a schematic structural diagram of the shipping assembly 60 in FIG. 2 .
  • the shipping assembly 60 may include a sliding frame 61 disposed above the pressing plate 50 and mounted on the frame 10 such as the first guide rail 111 , and a shipping member 62 mounted on the sliding frame 61 .
  • the sliding frame 61 can slide on the frame 10 such as the first guide rail 111 .
  • the sliding frame 61 is connected with the pressing plate 50 to slide on the frame 10 together with the pressing plate 50 in some situations.
  • a consignment piece 62 may be used to place a test card.
  • the carrier 62 is slidable relative to the carriage 61 .
  • the sliding direction of the carrier 62 relative to the sliding frame 61 is different from the sliding direction of the sliding frame 61 relative to the frame 10 .
  • the shipping assembly 60 when the shipping assembly 60 is stretched, the shipping piece 62 slides on the sliding frame 61 to slide to the first position outside the frame 10 to complete the stretching, and the detection card is placed when the shipping assembly 60 is in the extended state. Then, when the shipping assembly 60 is shrinking, the shipping piece 62 slides on the sliding frame 61 to slide to the second position in the frame 10 to complete the contraction. Swipe between third and fourth positions. In some embodiments, the shipping assembly 60 can be extended in the third position. In some embodiments, the shipping assembly 60 is extendable at a position between the third position and the fourth position.
  • the sliding frame 61 may include a fixed frame 611, a second sliding rail 612 mounted on the fixed frame 611 and slidingly connected with the frame 10 such as the first guide rail 111, a second rail 612 mounted on the fixed frame 611 and used for installing the shipping item 62.
  • the fixing frame 611 can be made of hard materials such as plastic, metal and the like.
  • the fixing frame 611 can be in a frame structure as a whole, and of course it can also be in other shapes, which will not be repeated here.
  • the second sliding rail 612 is disposed on the fixing frame 611 , and is used for realizing the sliding connection between the fixing frame 611 and the rack 10 when the second sliding rail 612 is slidingly connected to the rack 10 such as the first guide rail 111 .
  • the second guide rail 613 is installed on the fixing frame 611 for installing the shipping item 62 so that the shipping item 62 slides on the second guide rail 613 .
  • the extension direction of the second guide rail 613 can be consistent with the extension direction of the notch 514 , so that the consignment piece 62 slides on the second guide rail 613 and also slides in the notch 514 at the same time.
  • the driving device 614 may include a second driving assembly 6141 disposed on the fixing frame 611 and a lead screw 6142 connected with the second driving assembly 6141 .
  • the second driving assembly 6141 is used to drive the lead screw 6142 to rotate.
  • the second driving assembly 6141 can be connected and fixed to the fixing frame 611 by means of screws, bolts, clips, insertion, welding, bonding, and other connection methods.
  • the second driving component 6141 can be electrically connected with the control circuit board 40 to move under the control of the control circuit board 40 .
  • the lead screw 6142 is rotatably connected with the fixed frame 611 .
  • the extending direction of the lead screw 6142 may be consistent with the extending direction of the second guide rail 613 .
  • the outer surface of the lead screw 6142 is provided with external threads.
  • the lead screw 6142 is screwed with the consignment piece 62 by external threads, so that when the lead screw 6142 rotates, the lead screw 6142 and the consignment piece 62 rotate relatively, and under the cooperation of the lead screw 6142 and the second guide rail 613, the consignment piece 62 is in the second Slide on the guide rail 613.
  • the second driving component 6141 can be a motor.
  • a traction member 615 may be provided on the fixing frame 611 .
  • the traction member 615 may include a tension spring, for example, one end of the tension spring is connected to the fixing frame 611 , and the other end of the tension spring is connected to the hanging ear 574 .
  • FIG. 9 is a schematic structural diagram of the consignment piece 62 in FIG. 8 .
  • Shipment 62 may include a second track 613 mounted on The moving device 614 is such as the sliding seat 63 screwed with the lead screw 6142, the third driving assembly 64 installed on the sliding seat 63, and the card tray installed on the third driving assembly 64 and can be driven by the third driving assembly 64 to rotate. 65.
  • the sliding seat 63 slides on the second guide rail 613 to rotate relative to the lead screw 6142 under the drive of the driving device 614, and drives the third driving assembly 64 and the bracket 65 to move together, and can move to the outside of the frame 10.
  • the sliding seat 63 can also drive the third drive assembly 64, the card tray 65 to move to a position in the frame 10, the third drive assembly 64 can drive the card tray 65
  • the test card performs centrifugal movement to complete the centrifugation process of the test card.
  • the third driving assembly 64 can be connected and fixed to the sliding seat 63 by means of screwing, plugging, buckling, welding, bonding and the like.
  • the third drive assembly 64 can be a motor.
  • the output shaft of the motor can be connected and fixed with the bracket 65.
  • the card tray 65 is placed under the sliding seat 63 and is connected and fixed with the third driving assembly 64 .
  • the card tray 65 may include a card tray body 651 .
  • the card tray main body 651 can be made of hard materials such as plastic, metal and the like.
  • the card holder main body 651 is a revolving body, and the axis of the revolving body is arranged coaxially with the output shaft of the third driving assembly 64 .
  • the card holder body 651 is a circular disk-shaped structure.
  • the main body 651 of the card tray is provided with a rib 652 on a side close to the third driving assembly 64 .
  • the protruding ribs 652 are arranged to diverge around the part where the main body 651 of the card holder 651 is connected to the third driving assembly 64 as the center.
  • the protruding ribs 652 are evenly distributed around the part where the main body 651 of the card holder 651 is connected with the third driving assembly 64 .
  • Two adjacent protruding ribs 652 surround the main body 651 of the card holder to form a recess 653 for placing the detection card.
  • the number of the depressions 653 may be consistent with the number of the first heating elements 54 .
  • the number of the recessed parts 653 may also be less than the number of the first heating element 54 .
  • the number of the recessed parts 653 may be 6, of course, the specific number of the recessed parts 653 may also be adjusted according to the actual situation.
  • the main body of the card holder 651 is provided with a first fastening portion 654 in the concave portion 653 so as to be fastened with the detection card.
  • the first fastening portion 654 is located near the edge of the main body 651 of the holder.
  • the first fastening portion 654 is a groove or a protrusion.
  • the main body of the card holder 651 is provided with an accommodating hole 655 in the recessed portion 653 to make way for the detection card.
  • the concave portion 653 is a groove, and the depth of the groove can be the same as the thickness of the detection card, so that when the detection card is placed in the concave portion 653, the surface of the detection card and the rib 652 are away from the main body 651 of the card holder. surface is even.
  • the holder main body 651 can engage with the pressing member 53 when the pressing member 53 is in contact with the holder main body 651 .
  • the clamping fit relationship between the main body 651 of the card tray and the pressing member 53 can be a clamping structure such as a groove and a protruding column, a plug-in structure, a buckle structure, or the like.
  • magnetic force connecting parts such as permanent magnets or electromagnets can be arranged inside the main body 651 of the card holder and/or ribs 652.
  • the main body 651 of the card tray is provided with a first positioning member 656 (as shown in FIG. 10 ) on the side away from the third drive assembly 64, so that when the test card is transported to the test card detection seat 30, the The detection card is positioned such that the detection card is placed at a predetermined position for detection of the detection card.
  • the first positioning member 656 is a positioning block, and the positioning block extends away from the main body 651 of the card holder, and the cross-sectional area perpendicular to the extending direction gradually changes and gradually decreases.
  • the positioning block may be conical.
  • the consignor 62 can be located at the fourth position.
  • FIG. 10 and FIG. 11 are structural schematic diagrams of different angles of cooperation of the resisting plate 50 and the shipping assembly 60 in FIG. 2 .
  • the resisting plate 50 is connected with the shipping assembly 60
  • the components of the shipping assembly 60 except the card tray 65 are first assembled together, and then the sliding frame 61 in the shipping assembly 60 is placed on the pressing plate 50 .
  • the second slide rail 612 in the sliding frame 61 is opposite to the first slide rail 58 of the pressing plate 50 so as to be installed on the rack 10 such as the first guide rail 111 of the rack main body 11 together.
  • the pressing plate 50 and the shipping assembly 60 can also be installed on different first guide rails 111 respectively.
  • part of the first guide rails 111 may only be installed with the pressing plate 50 or the shipping assembly 60 .
  • the test card detection base 30 may include a support frame 70 connected and fixed to the frame 10 , a support base 80 mounted on the support frame 70 , and a detection assembly 90 mounted on the support frame 70 and the support base 80 .
  • the supporting base 80 is located under the pressing plate 50 so as to carry the testing card transported by the testing card transporting base 20 such as the consignment assembly 60 .
  • the detection component 90 is electrically connected with the control circuit board 40 . When the detection component 90 places the detection card on the support base 80 , it uses the excitation light to perform a series of detection processes on the detection card to generate a detection signal, and sends the detection signal to the control circuit board 40 .
  • the support frame 70 is a frame structure as a whole and can be located at the bottom of the frame 10 .
  • the support frame 70 may include a base 71 arranged at the bottom of the frame 10 and fixedly connected with the frame 10 , and a fixing seat 72 installed on the top of the base 71 .
  • the support base 80 may include a support base main body 81 installed on the base 71, a detection chamber assembly 82 installed on the support base main body 81, a sample loading chamber installed on the support base main body 81 and cooperating with the detection chamber assembly 82 to support the detection card
  • the detection chamber assembly 82 can be installed on the support base 80 at a position opposite to the first heating element 54 to cooperate with the first heating element 54 .
  • the sample loading chamber assembly 83 can be installed on the support base 80 at a position opposite to the second heating element 55 to cooperate with the second heating element 55 .
  • the detection chamber assembly 82 cooperates with the sample loading chamber assembly 83 to carry out the detection card. support and heat treatment.
  • the detection chamber assembly 82 can also be used to perform excitation light detection on the detection card.
  • the detection chamber assembly 82 and the sample application chamber assembly 83 are electrically connected to the second circuit board 84 to realize the heating control of the detection chamber assembly 82 and the sample application chamber assembly 83 .
  • FIG. 14 is a schematic structural view of the main body 81 of the support seat in FIG. 13 .
  • the main body 81 of the support seat can be made of hard materials such as plastic, metal and the like.
  • the main body 81 of the supporting base can be in the shape of a plate as a whole.
  • the top of the main body 81 of the support seat can define a placement slot 811 to make way for the card tray 65 .
  • the main body 81 of the support base defines a fastening hole 812 in the slot 811 for matching with the sample chamber assembly 83 .
  • the main body 81 of the support seat is also provided with a second positioning member 813 in the placement slot 811 to cooperate with the first positioning member 656 to locate the position of the detection card.
  • the second positioning member 813 can be a positioning groove opened by the main body of the support seat 81 in the placement groove 811, so that the first positioning member 656, such as a positioning block, is placed in the second positioning member 813, such as a positioning groove. Realize the positioning of the detection card position.
  • the shape of the second positioning member 813 such as a positioning block may match the shape of the first positioning member 656 such as a positioning groove.
  • the positioning and matching relationship between the main body of the support seat 81 and the card tray 65 is not limited to the matching relationship between the second positioning member 813 and the first positioning member 656, it can also be the magnetic force between the magnets, the electromagnet
  • the coordination relationship with the electromagnet, such as the magnetic force, can of course also be other coordination relationships, which will not be described in detail.
  • a plurality of extending slots 814 are evenly distributed around the placement slot 811 of the supporting seat main body 81 .
  • the extension groove 814 communicates with the placement groove 811, so that the support base body 81 forms an assembly platform 815 between two adjacent extension grooves 814, and the detection card can be placed on the assembly platform 815, and the extension groove 814 makes way for the detection card so that the assembly platform 815 supports and fastens the detection card.
  • the main body 81 of the support seat is provided with a receiving hole 816 at the position of the assembly platform 815 , so as to install the detection chamber assembly 82 in the receiving hole 816 .
  • the detection cavity assembly 82 is installed in the main body 81 of the support base 81 such as the receiving hole 816 .
  • the detection chamber assembly 82 may include at least one light detection member 821 , and the specific number of the light detection members 821 may be one of 1, 2, 3, 4, 5, 6 .
  • the photodetection element 821 can be arranged corresponding to one first heating element 54, so that the two cooperate to heat a detection card.
  • FIG. 15 is a schematic structural diagram of the light detection element 821 in FIG. 13 .
  • the light detection element 821 may include a detection seat 8211 disposed in the support seat main body 81 such as the receiving hole 816 .
  • the detection seat 8211 can be made of hard materials such as plastic, metal and the like.
  • the detection seat 8211 extends toward one side of the receiving hole 816 to extend into the receiving hole 816 .
  • the detection seat 8211 is flush with the surface of the assembly platform 815 on the side of the support seat main body 81 where the assembly platform 815 is provided, so as to improve the appearance of the support seat 80 for supporting the detection card.
  • the detection base 8211 is provided with an excitation fiber 8212 in the extending direction, so that the excitation fiber 8212 emits light such as excitation light to the detection card.
  • the detection seat 8211 is provided with a receiving optical fiber 8213 at a position forming an angle with the extending direction.
  • the receiving optical fiber 8213 is used to receive the excitation light emitted by the excitation optical fiber 8212 and the fluorescence formed by the excitation light irradiating the detection card.
  • the detection base 8211 is provided with a heating element accommodating groove 8211a on the side where the exciting optical fiber 8212 is disposed, for accommodating heating elements such as heating resistors.
  • the detection seat 8211 can realize the heating of the detection card through the heating device.
  • the heating element in the heating element accommodating groove 8211a can be electrically connected with the second circuit board 84 to realize heating under the control of the second circuit board 84 .
  • the detection seat 8211 is provided with a heating element accommodating groove 8211b on a side close to the sample loading chamber assembly 83 for accommodating heating elements such as heating resistors.
  • the detection seat 8211 can realize the heating of the detection card through the heating device.
  • the heating element in the heating element accommodating groove 8211b can be electrically connected with the second circuit board 84 to realize heating under the control of the second circuit board 84 .
  • the detection seat 8211 can be called "the third heating element".
  • the detection seat 8211 can be integrated with the main body 81 of the support seat.
  • FIG. 16 is a schematic structural diagram of the sample loading chamber assembly 83 in FIG. 13 .
  • the sample chamber assembly 83 may include a support plate 831 fixed on the fixing base 72 and a sample chamber mounting base 832 mounted on the support plate 831 .
  • the mounting seat 832 of the sample loading chamber is used for fixing the detection card, and is also used for heating the detection card.
  • the mounting seat 832 of the sample loading chamber cooperates with the second heating element 55 to heat the detection card.
  • the supporting plate 831 can be made of hard materials such as plastic, metal and the like. The whole can be in a plate-like structure, and of course it can also be in other structures, which will not be described in detail.
  • the supporting plate 831 can be fixed on the fixing base 72 by means of screwing, inserting, bonding, welding and the like.
  • the supporting plate 831 can be fixed on the fixing seat 72 by means of screwing, inserting, bonding, welding and the like.
  • the supporting plate 831 can be omitted, and the mounting base 832 of the sample loading chamber can be fixedly connected with the fixing base 72 directly.
  • the fixing seat 72 when the fixing seat 72 is omitted, the supporting plate 831 can be fixed on the base 71 .
  • the mounting base 832 of the sample loading chamber is used for placing the detection card.
  • the sample chamber mount 832 may include a mount body 8321 .
  • the mounting base body 8321 can be made of hard heat-conducting materials such as plastic or metal as a whole.
  • the mount body 8321 is used to be placed in the support body 81 such as the fastening hole 812 .
  • the side of the mounting base body 8321 away from the support plate 831 is provided with a sample loading chamber placement groove 8322 for installing a detection card.
  • the mounting base body 8321 is provided with a heating element accommodating groove 8323 for accommodating heating elements such as heating resistors, so that the mounting base body 8321 can heat the detection card.
  • the heating device can be electrically connected with the second circuit board 84 to be heated under the control of the second circuit board 84 .
  • the heating device is arranged in the mounting base body 8321, it has the effect of heating the detection card. Therefore, the mounting seat 832 of the sample loading chamber can be called a "fourth heating element”.
  • first heating element For names such as “first heating element”, “second heating element”, “third heating element”, “fourth heating element”, “fifth heating element”, “sixth heating element” and “heating element”, in some embodiments Can be converted to each other.
  • first heating element in other embodiments is referred to as “second heating element”
  • second heating element in other embodiments is referred to as “first heating element”.
  • the mounting seat body 8321 is provided with an abutting portion 8324 on one side edge of the sample loading chamber seating groove 8322 for abutting against the detection card.
  • the abutting portion 8324 can also be used to position the detection card.
  • the second circuit board 84 can be electrically connected to the heating element in the detection chamber assembly 82 and the heating element in the sample adding chamber assembly 83 respectively, so as to control the heating element for heating.
  • the second circuit board 84 can be a ring structure, and can be sleeved around the sample chamber assembly 83 .
  • the second circuit board 84 can be directly fixed on the side of the support base body 81 close to the support frame 70 , for example, can be fixed by means of welding, plugging, buckling, bonding, screwing and the like.
  • the second circuit board 84 may also be directly fixed on the supporting frame 70 such as the fixing base 72 .
  • the second circuit board 84 may also be directly fixed on the supporting frame 70 such as the base 71 .
  • the second circuit board 84 may also be directly fixed on the sample loading chamber assembly 83 such as the support plate 831 .
  • the second circuit board 84 can be omitted without sharing the working pressure for the control circuit board 40, and the heating device in the detection chamber assembly 82 and the heating device in the sample chamber assembly 83 can be directly connected with The control circuit board 40 is electrically connected.
  • the detection assembly 90 may include a light generator 91 mounted on the support frame 70 such as the base 71, a light receiver 92 mounted on the support frame 70 such as the base 71, and a detection chamber assembly mounted on the support base 80 such as the support base body 81 82 (that is, the detection cavity assembly 82 of the support base 80 described above, the detection cavity assembly 82 may be a common component of the support base 80 and the detection assembly 90).
  • both the light generator 91 and the light receiver 92 are electrically connected to the control circuit board 40 .
  • the light generator 91 is used to generate excitation light, and can generate excitation light under the control of the control circuit board 40 .
  • the excitation light can be transmitted to the detection cavity assembly 82 to excite the detection card and generate fluorescence, the fluorescence can be received by the light receiver 92 , and the light receiver 92 can generate a detection signal under the control of the control circuit board 40 .
  • the detection signal is transmitted to the control circuit board 40 and the control circuit board 40 processes and generates diagnostic data.
  • FIG. 17 is a schematic structural diagram of the light generator 91 in FIG. 12 .
  • the number of light generators 91 may be one or more. Specifically, the number of light generators 91 may be one of 2, 3, 4, 5, 6.... In an embodiment, the number of light generators 91 may be two, specifically a first light generator 911 and a second light generator 912 .
  • Both the first light generator 911 and the second light generator 912 can be fixed on the fixing base 72 , and can be fixed on the fixing base 72 by plugging, welding, screwing, bonding, buckling, and the like.
  • the excitation light output ends of the first light generator 911 and the second light generator 912 communicate with the excitation fiber 8212 .
  • the optical receiver 92 is used to connect with the receiving optical fiber 8213 to receive the fluorescence, and then transmit the detection signal triggered by the fluorescence to the control circuit board 40 .
  • the light receiver 92 has a ring shape and is arranged around the light generator 91 .
  • Light receiver 92 may include a light sensor such as a photodiode. Light sensors such as photodiodes can be illuminated by fluorescent light to generate electrical signals.
  • control circuit board 40 may be provided with electronic components such as a processor and a memory.
  • the control circuit board 40 may include a first sub-control circuit board 41 and a second sub-control circuit board 42 fixed at different positions of the rack 10 such as the rack body 11 .
  • the first sub-control circuit board 41 is electrically connected to the second sub-control circuit board 42 .
  • the first sub-control circuit board 41 can be electrically connected to the frame 10 such as the first driving assembly 12 so as to control the sliding position of the test card delivery base 20 relative to the frame 10 .
  • the first sub-control circuit board 41 can be electrically connected with the pressure plate 50, such as the first circuit board 56, so as to control the electromagnetic element 52, and carry out magnetic force adsorption to the pressing element 53, so as to control the first heating element 54 and the second heating element.
  • Part 55 is for heating the detection card.
  • the first sub-control circuit board 41 can be electrically connected with the shipping component 60 such as the second driving component 6141 , so as to control the third driving component 64 and the card tray 65 to slide relative to the carriage 61 together.
  • the first sub-control circuit board 41 can be electrically connected to the shipping component 60 such as the third driving component 64 so as to control the third driving component 64 to drive the card holder 65 to perform centrifugation on the detection card.
  • the first sub-control circuit board 41 can be electrically connected to the second circuit board 84 to be indirectly electrically connected to the detection chamber assembly 82 such as a heating element, so as to control the detection seat 8211 and heat the detection card.
  • the first sub-control circuit board 41 can be electrically connected to the second circuit board 84 to be indirectly electrically connected to the sample chamber assembly 83 such as a heating device, so as to control the sample chamber installation seat 832 to heat the detection card.
  • the first sub-control circuit board 41 can be electrically connected with a detection component 90 such as a light generator 91 so as to control the light generator 91 to emit excitation light.
  • a detection component 90 such as a light generator 91 so as to control the light generator 91 to emit excitation light.
  • the first sub-control circuit board 41 can be electrically connected with a detection component 90 such as a light receiver 92 so as to control the light receiver 92 to receive fluorescence.
  • a detection component 90 such as a light receiver 92 so as to control the light receiver 92 to receive fluorescence.
  • the second sub-control circuit board 42 can be installed above the rack 10 such as the rack main body 11 .
  • the second sub-control circuit board 42 may be provided at a position where the case is opposite to the frame main body 11 .
  • the second sub-control circuit board 42 can be electrically connected to input devices such as a display, a keyboard, and a code scanning device 14, so as to input control instructions to the molecular diagnostic device 100 such as the control circuit board 40 through the input device, so that the molecular diagnostic device 100 can pass through the control circuit board.
  • input devices such as a display, a keyboard, and a code scanning device 14, so as to input control instructions to the molecular diagnostic device 100 such as the control circuit board 40 through the input device, so that the molecular diagnostic device 100 can pass through the control circuit board.
  • 40 pairs of test card delivery Control of seat 20 and/or test card test seat 30 40 pairs of test card delivery Control of seat 20 and/or test card test seat 30.
  • the second sub-control circuit board 42 and the first sub-control circuit board 41 can be integrated into one control circuit board.
  • a detection card which can be used in the molecular diagnostic device 100 in the above-mentioned embodiment to complete the detection of the samples loaded on the detection card and further process to form diagnostic data.
  • FIG. 18 is a schematic structural diagram of a test card in an embodiment of the present application.
  • the test card 93 is also called a molecular diagnostic centrifuge test card or a test card.
  • the detection card 93 may include a body 94 provided with a sample loading chamber, a flow channel, a waste liquid chamber, an isolation chamber and a detection chamber, an isolation layer 95 covering one side of the body 94, and a cover covering the sample loading chamber of the body 94 96.
  • FIG. 19 is a cross-sectional view along the line L-L of the detection card 93 in FIG. 18
  • FIG. 20 is a schematic diagram of the three-dimensional structure of the detection card 93 in FIG. 18 .
  • the body 94 is made of hard material such as plastic.
  • the body 94 as a whole can be a plate-like structure. It is generally fan-shaped, and specifically can be fan-shaped, fan-bladed or pie-shaped.
  • the body 94 is fan-shaped formed by sequentially connecting two straight sides and one arc-shaped side end to end.
  • the body 94 is a sector ring formed by sequentially connecting a straight line side, an outer arc-shaped side, a straight line side, and an inner arc-shaped side end to end.
  • the body 94 can also be in other shapes, which will not be repeated here.
  • the angle between the two straight sides of the fan-shaped structure of the body 94 may be 40°-60°, the diameter of the inner arc side may be 10mm-100mm, and the diameter of the outer arc side may be 100mm-200mm.
  • detection cards 93 at least 6 detection cards can be arranged in the detection plane of the molecular diagnostic device 100 to form a circular surface, so that at least 6 detection cards 93 can be detected simultaneously, improving the overall detection efficiency , which can meet the needs of large-scale detection.
  • the body 94 is close to the center of the outer arc edge or the inner arc edge and protrudes toward a side away from the isolation layer 95 to provide a mounting portion 941 .
  • a sample adding chamber 9411 is recessed on a side of the body 94 close to the isolation layer 95 and at a position opposite to the mounting portion 941 , for sample addition in the sample adding chamber 9411 .
  • the sample loading chamber 9411 is mainly used for pretreatment of samples (liquid samples), and the pretreatment methods may include one or more methods, such as chemical treatment, heat treatment, enzyme treatment and physical separation.
  • the volume of the sample loading chamber 9411 is approximately 200-2000 ⁇ l. Dried reagents can be preloaded in the sample loading chamber 9411, and can be air-dried/dried in situ, or can be added into the sample loading chamber 9411 as freeze-dried reagents.
  • the body 94 is provided with a second fastening portion 942 on a side away from the isolation layer 95 and near the outer arc edge, so as to cooperate with the shipping component 60 such as the first fastening portion 654 .
  • the second fastening portion 942 may be a protrusion. It can be understood that the positions of the first fastening portion 654 and the second fastening portion 942 can be interchanged, and the first fastening portion 654 and the second fastening portion 942 can also be fastened in other ways.
  • the main body 94 is bent toward the side away from the isolation layer 95 at the edge of one straight line close to the outer arc edge, and the first stopper 943 is bent toward the side away from the isolation layer 95 at the edge of the other straight line close to the outer arc edge.
  • a second limiting portion 944 protrudes from one side. The first limiting part 943 of the body 94 cooperates with the second limiting part 944 to fix the detection card 93, so that the centrifugation process of the detection card 93 can be carried out smoothly.
  • a waste liquid chamber 9441 is recessed at a position opposite to the limiting portion 944 .
  • Each socket set may include a first socket 945 and a second socket 946 .
  • the connecting line between the first socket part 945 and the second socket part 946 may pass through the center of the outer arc edge.
  • the first insertion portion 945 is disposed between the installation portion 941 and the second insertion portion 946 .
  • the arrangement of the first insertion part 945 and the second insertion part 946 can cooperate with the detection card detection seat 30 such as the isolation groove 8213 and the detection groove 8212 .
  • An isolation chamber 9451 is recessed on a side of the body 94 close to the isolation layer 95 and opposite to the first insertion portion 945 .
  • the isolation cavity 9451 is provided with a meltable isolation body.
  • the separator is switchable between a molten state and an unfused state (usually solid).
  • the isolator can be controlled to be in an unmelted state. At this time, the isolator can prevent the sample from entering the detection cavity 9461 (as shown in FIG. 20 ) through the flow channel.
  • the separator can be paraffin, microcrystalline, synthetic, or natural wax.
  • a detection cavity 9461 is recessed on a side of the body 94 close to the isolation layer 95 and opposite to the second insertion portion 946 .
  • the detection chamber 9461 is provided with reagents.
  • the isolation cavity 9451 communicates with the detection cavity 9461 on a side close to the isolation layer 95 .
  • the isolation body in the isolation cavity 9451 can also be used to seal the isolation reagents, so as to prevent the reagents from entering the isolation cavity 9451 in reverse. Reagents are maintained within detection chamber 9461.
  • the isolator When performing the test, the isolator can be controlled to be in a molten state, and at this time, the sample can enter the detection chamber 9461 through the sample loading chamber 9411 to react with the reagent in the detection chamber 9461 to complete the detection.
  • Reagents and meltable spacers can be stacked in the detection chamber 9461 .
  • the separator can be paraffin, microcrystalline, synthetic, or natural wax.
  • the isolator is characterized in that it is solid at room temperature and low temperature, and becomes liquid when heated to a specific temperature, and has no inhibitory effect on nucleic acid amplification reactions.
  • the reagents can be dry reagents, and the dry reagents include primers and DNA (deoxyribonucleic acid, deoxyribonucleic acid) binding dyes, enzymes, magnesium sulfate, potassium chloride, dNTPs (Nucleoside triphosphate, deoxyribonucleic acid) used in the amplification reaction.
  • the dry reagent is loaded into the detection chamber 9461 in a liquid state, and the dry reagent is formed through a drying process.
  • the temperature of the drying process is lower than the melting temperature of the isolator.
  • the drying process includes air drying, oven drying, and freeze drying. During the detection and heating process, both the reagent and the spacer are in a liquid state. Since the specific gravity of the spacer is smaller than that of the reagent, the spacer is displaced out of the detection chamber 9461 under the action of the centrifugal field, so that the reaction and detection are not affected.
  • the isolator is loaded into the detection cavity 9461 in a molten state and is formed by natural solidification or cooling and solidification. in untested At this time, the isolation body can be controlled to be in an unmelted state, and at this time, the sealed and isolated storage of the reagent can be realized through the isolation body.
  • the isolator can be controlled to be in a melting state, for example, by heating the detection card 93, so that the isolator is heated and melted.
  • the isolator can move out of the detection cavity 9461 and flow to the isolation cavity 9451, and the sample can enter the detection cavity 9461, and then the spacer solidifies again to block the mouth of the detection cavity 9461, thereby forming a mutual isolation seal for multiple detection cavities 9461, so that the detection cavities 9461 can react independently or test.
  • the main body 94 is provided with a flow channel 947 on a side close to the isolation layer 95 to communicate with the sample injection chamber 9411 and the isolation chamber 9451 .
  • the body 94 is provided with an abutting groove 948 on a side away from the isolation layer 95 and opposite to the flow channel 947 , so as to cooperate with the abutting portion 8324 .
  • the abutting part 8324 can be placed in the abutting groove 948 to heat the part of the flow channel 947 to prevent water vapor from condensing in the flow channel 947, thereby reducing the impact on the subsequent detection process and improving detection accuracy.
  • the abutment groove 948 may be omitted.
  • the isolation layer 95 can be a film structure, and of course can also be other structures.
  • the isolation layer 95 can be made of compacted adhesive, ultraviolet curing adhesive or optical grade double-sided adhesive, or can be made of a material similar to that of the body 94 .
  • the isolation layer 95 can be attached to the body 94, and can be sealed and fixed by, for example, ultrasonic welding, laser welding, adhesive sealing, etc., so as to isolate the flow channel 947, the waste liquid chamber 9441, the isolation chamber 9451 and the detection chamber 9461.
  • the isolation layer 95 can be integrated with the body 94 .
  • the cover body 96 covers the mouth of the sample adding chamber 9411 . To seal and isolate the sample loading chamber 9411. When it is necessary to add a sample, the cover 96 can be opened, the sample can be added to the sample adding chamber 9411, and then the cover 96 can be closed.
  • the cover body 96 can block water and ventilate, which can discharge the water vapor generated during the heating process and reduce the air pressure in the molecular diagnostic centrifugal test card, so as to ensure a good ventilating effect, and can block the aerosol and biological
  • the escape of pollutants such as molecules avoids the detection of pollution to personnel and the environment.
  • the detection card 93 When the detection card 93 is centrifugally rotated, the sample liquid passes through the sample adding chamber 9411 and the flow channel 947 . At this time, the spacer is solid, thereby sealing the detection chamber 9461 , and the sample liquid cannot flow into the detection chamber 9461 . After the sample liquid is heated, the spacer is heated and melted and flows to the detection chamber 9461 , so that the flow channel 947 can communicate with the detection chamber 9461 , and the sample liquid can flow into the detection chamber 9461 through it.
  • the spacer Since the specific gravity of the spacer is smaller than that of the reagent, the spacer is displaced onto the reagent under the action of the centrifugal field, which does not affect the reaction and detection, and at the same time, the detection chamber 9461 can be sealed.
  • test card 93 filled with the sample when the test card 93 filled with the sample is centrifuged, in order to ensure that the test card 93 filled with the sample is evenly distributed on the card tray 65 and reduce the noise generated by the uneven distribution of the test card 93 during the centrifugation process,
  • the test cards 93 not filled with samples can be used as trim cards, and the test cards 93 filled with samples can be uniformly distributed on the card tray 65 for centrifugation.
  • the isolation cavity 9451 may not be provided with an isolation body.
  • the detection card 93 when used as a trim card, no reagents and spacers may be set in the detection cavity 9461 .
  • the body 94 and the cover 96 may be integrally structured.
  • the detection card 93 when used as a trim card, no reagents may be provided in the sample loading chamber 9411 .
  • the detection card 93 when used as a trim card, at least one structure of the flow channel 947 , the isolation chamber 9451 , the waste liquid chamber 9441 , and the cover 96 may be omitted.
  • the sample loading chamber 9411 can be omitted, and a third fastening part integrated with the body 94 is provided at the position where the sample loading chamber 9411 is provided.
  • the third fastening part is a protrusion, so as to be installed on the mounting seat 832 of the sample injection chamber.
  • the trim card can not only play the role of trimming and noise reduction during centrifugation, but also set a reference membrane at the bottom of the detection chamber 9461 to replace reagents and spacers, and then play a role in calibrating the detection component 90 of the molecular diagnostic equipment
  • the function is to improve the detection accuracy of the detection component 90 in the molecular diagnostic equipment.
  • the composition of the reference film can include a fluorescent indicator.
  • the components of the reference film can also include auxiliary reagents, which can help the fluorescent indicator to form a film.
  • Fluorescent indicators refer to a class of substances that can produce fluorescence when irradiated by laser light.
  • the fluorescent indicator can generate fluorescence under the excitation light of the light generator 91 , and the light receiver 92 can receive the fluorescent light generated by the fluorescent indicator.
  • the reference membrane can be replaced by a liquid fluorescent indicator and other types of auxiliary reagents to be filled in the detection cavity 9461 .
  • the form of the fluorescent indicator is not limited, as long as it can generate fluorescence under the excitation light of the light generator 91 .
  • Some embodiments of the present application also provide a detection method based on the detection card 93 described above. This method can be used in the molecular diagnostic device 100 in the above embodiments. Please refer to FIG. 21 , which is a schematic diagram of the process of using the detection card in FIG. 20 . The specific steps can be as follows:
  • Step S2101 The sample loading chamber receives the sample.
  • the heating method can be a metal heating block, heating air flow, electromagnetic waves (infrared radiation, laser, microwave) and other methods.
  • the heating area of the detection card can be the area near the sample loading chamber.
  • the heating process needs to be heated to a specified temperature, such as 90°C. After reaching the specified temperature, keep warm for 3-10 minutes according to the specified requirements to achieve pretreatment. After the pretreatment is completed, the temperature of the sample liquid is lowered to a specified temperature, such as 60°C.
  • Step S2102 The detection card is rotated by the centrifugal force so that the sample flows to the detection cavity through the flow channel.
  • Centrifuge the test card spin control For example, the direction of rotation can be controlled to be clockwise, and the rotation speed is greater than 1000rpm. The time is about 10-15s.
  • the sample liquid can flow from the sample loading chamber to the detection chamber through the flow channel, so as to facilitate subsequent filling of the sample in the detection chamber. Excess sample fluid goes to the waste chamber.
  • Step S2103 heating and melting the spacer, so that the sample flows into the detection chamber and mixes with the reagent in the detection chamber.
  • heat treatment needs to be performed on the area near the detection chamber, so that the temperature is higher than the melting point of the spacer, and then the spacer is melted, so that the sample is mixed with the reagent in the detection chamber.
  • Step S2104 Centrifugal rotation, so that the spacer is replaced with the sample in the detection chamber, and the inlet end of the detection chamber is sealed.
  • the motor can rotate clockwise, the rotation speed is greater than 1000rpm, and the rotation time is 10-15s.
  • the sample enters the detection chamber, and the spacer and the aqueous solution in the detection chamber are replaced, and the spacer is transferred to the inlet port of the detection chamber, thereby completing the sealing of each detection chamber.
  • change the motor control parameters to make the detection card rotate clockwise and counterclockwise alternately.
  • the detection card can be controlled to rotate clockwise at a rotation speed of 3000rpm for 1s, and then rotate counterclockwise at a rotation speed of 3000rpm for 1s and alternately rotate 10-15 times.
  • the sample and the reagent in the detection chamber can be completely dissolved and mixed by this way of alternating clockwise and counterclockwise rotation.
  • the isolator flows to the inlet end of the detection chamber under the action of centrifugal force, so as to seal the inlet end of the detection chamber.
  • Step S2105 Detect the mixed mixture.
  • an amplification reaction and detection are required. If real-time detection is used, the detection and amplification reaction are performed simultaneously, and if end-point detection is used, detection is performed after the amplification is completed.
  • the amplification reaction can be realized in the following way: heating the vicinity of the detection chamber, and controlling the temperature in the range of 60°C-75°C. After reaching the specified temperature, according to the specified requirements, keep warm for 30-60 minutes to complete the amplification reaction.
  • the control circuit board 40 sets basic information such as the quantity, type, heating temperature, number of rotations, and operating parameters of the detection card 93 through the input device. After the basic information is set, the detection of the detection card 93 can be further enabled through the input device.
  • test card 93 loaded with samples.
  • the first driving assembly 12 controls the rotation of the lead screw 13 , so that the pressing plate 50 drives the shipping assembly 60 to slide on the first guide rail 111 to the side away from the detection card detection seat 30 .
  • the pressing plate 50 reaches a predetermined position.
  • the first drive assembly 12 stops running.
  • the second driving assembly 6141 makes the consignment piece 62 slide along the second guide rail 613 to the side close to the code scanning device 14 through the lead screw 6142 .
  • Consignment 62 arrives at a predetermined location.
  • the second drive assembly 6141 stops running.
  • the test card 93 loaded with the sample is placed at the recessed portion 653 of the consignor 62 such as the card tray 65 .
  • the detection card 93 such as the mounting portion 941 is placed in the accommodating hole 655 .
  • the detection card 93 for example, the second fastening portion 942 is fastened with the first fastening portion 654 of the card tray 65 , and the placement of one detection card 93 is completed.
  • the control circuit board 40 scans the image of the information identification of the detection card 93 on the card tray 65 through the code scanning device 14, and judges whether it is the detection card 93 predetermined by the user. If not, an early warning prompt will be given. If so, proceed to the next step.
  • the third drive assembly 64 starts to rotate, and drives the card holder 65 to rotate, so that the next recess 653 where the test card 93 can be placed reaches a predetermined position, and then the next test card 93 is placed.
  • the detection cards 93 After the detection cards 93 are placed in the recessed portion 653 on the card holder 65 , the detection cards 93 will be uniformly distributed on the card holder 65 . If the number of detection cards 93 is not enough to be evenly distributed on the card holder 65, a trim card can be placed at the recess 653 of the card holder 65, so that the trim cards and the detection cards 93 are uniformly distributed on the card holder 65. So far the detection card 93 has been placed.
  • the second driving assembly 6141 makes the consignment piece 62 slide along the second guide rail 613 to the side away from the code scanning device 14 through the lead screw 6142 . Consignment 62 arrives at a predetermined location.
  • the second drive assembly 6141 stops running.
  • the first driving assembly 12 controls the rotation of the lead screw 13 , so that the pressing plate 50 drives the shipping assembly 60 to slide on the first guide rail 111 to the side close to the detection card detection seat 30 .
  • the shipping element 62 such as the card holder 65
  • the support seat 80 such as the support seat main body 81 .
  • the first positioning piece 656 on the side of the card holder 65 facing the main body 81 of the support seat will extend into the second positioning piece 813. Due to the special structure of the first positioning piece 656, the first positioning piece 656 will be easily placed on the second positioning piece. In 813, the positioning of the detection card 93 is realized.
  • the detection card 93 will be located on the support base 80 .
  • the detection card 93 such as the installation part 941 will be placed in the sample chamber installation groove 8322 of the sample chamber mounting base 832 .
  • the detection card 93 such as the first insertion part 945 will be placed in the light detection part 821 such as the isolation groove 8213 .
  • the detection card 93 such as the second insertion part 946 will be placed in the light detection part 821 such as the detection slot 8212 .
  • the detection card 93 such as the first limiting portion 943 will be placed in the main body 81 of the support seat 81 such as the extension groove 814 and abut against the assembly platform 815 .
  • the detection card 93 such as the second limiting portion 944 is placed in the main body 81 of the support base 81 such as the extension groove 814 and abuts against the assembly platform 815 . So far, the placement of the detection card 93 on the support base 80 is completed.
  • the pressing plate 50 reaches a predetermined position.
  • the first drive assembly 12 stops running. At this time, the pressing plate 50, for example, the first heating element 54 abuts against the position where the detection card 93 is provided with the isolation chamber 9451 and the detection chamber 9461, and the pressing member 53 clamps the cover body 96, and the fixing of the pressing member 53 is loosened. .
  • the heating device in the sample loading chamber assembly 83 such as the sample loading chamber mounting base 832 and the heating device in the second heating element 55 are heated to complete the detection card 93 such as the sample loading chamber 9411. heating.
  • the heating pretreatment of the sample is realized.
  • the first driving assembly 12 controls the rotation of the lead screw 13 , so that the pressing plate 50 drives the shipping assembly 60 to slide on the first guide rail 111 to the side away from the detection card detection seat 30 .
  • the pressing plate 50 reaches a predetermined position.
  • the first drive assembly 12 stops running.
  • the third driving assembly 64 starts to rotate, and drives the card holder 65 to rotate, so as to realize the centrifugal processing of the detection card.
  • the detection card 93 is delivered to the support base 80 such as the support base main body 81 again.
  • the heating element in the first heating element 54 is controlled and heated, and the heating element in the photodetection element 821 is controlled and heated.
  • the secondary heating of the detection card 93 is realized.
  • test card 93 is centrifuged again.
  • the detection card 93 is transported to the support base 80 such as the support base main body 81 .
  • the light generator 91 emits excitation light to excite the mixture in the detection chamber 9461 of the detection card 93 in the detection groove 8212 .
  • the light receiver 92 receives the fluorescent light.
  • the detection signal is received by the control circuit board 40 and processed to form diagnostic data.
  • FIG. 22 is a flowchart of a control method based on a multi-throughput centrifugal platform in an embodiment of the present application.
  • the method can include:
  • Step S2201 Obtain the number of testing cards.
  • a multi-throughput centrifugal platform such as the molecular diagnostic device 100 detects the detection card 93 , the detection card 93 needs to be centrifuged.
  • a multi-throughput centrifugal platform such as the molecular diagnostic device 100 is provided with a card holder 65 for placing the detection card 93 .
  • Each card tray 65 can be provided with a plurality of locking positions (that is, the recessed portion 653 in FIG. 9 ). For example, 6 card positions can be set on the card holder 65 in FIG. 9 . It can be understood that different multi-throughput centrifugal platforms have different numbers of card positions on the tray.
  • the multi-throughput centrifugal platform such as the molecular diagnostic equipment 100
  • centrifuges the detection card 93 it will place the detection card symmetrically on the card holder 65, so that the detection card 93 is placed on the card position, so that Weight distribution on the Cato 65 is balanced. If the detection card 93 is placed on the card position, the weight distribution on the card tray 65 will be unbalanced, and an eccentric force will be generated, which will cause a lot of noise during the centrifugation process of the multi-throughput centrifugal platform such as the molecular diagnostic device 100 .
  • the multi-throughput centrifugal platform such as the molecular diagnostic device 100 always fills the card tray 65 with the maximum number of detection cards, so there will be no problem of unbalanced weight distribution on the card tray 65 .
  • special cases may also occur.
  • the number of detection cards is not enough to fill the tray 65 , and there is a problem that the weight distribution on the tray 65 is not balanced. This situation is more likely to occur especially when the detection card 93 is placed manually.
  • the number of detection cards is particularly important as the basic data.
  • the number of test cards can be input by the user into the system of the multi-throughput centrifugation platform such as the molecular diagnostic device 100 through input devices such as a display, a keyboard, and a code scanning device 14 according to the actual situation, so that the multi-throughput centrifugation platform such as The system of the molecular diagnostic device 100 assists the user in completing the balancing process of the detection card 93 on the card tray 65 according to the number of detection cards.
  • the trim card described in the above embodiment can be introduced so that the number of cards such as detection cards and trim cards is sufficient to balance the weight distribution on the card holder 65.
  • the number of detection cards is 1, supplemented by 1 trimming card, then the sum of the number of cards is 2, which is enough to balance the weight distribution on the card tray 65 .
  • the number of detection cards is 5, supplemented by 1 trimming card, then the sum of the number of cards is 6, which is enough to balance the weight distribution on the card tray 65 .
  • Step S2202 Determine the card tray rotation strategy of the multi-throughput centrifugal platform corresponding to the number of detection cards.
  • a multi-throughput centrifugal platform such as the molecular diagnostic device 100
  • the card tray 93 slides to the side of the code scanning device 14
  • only one card position will be exposed at the drop bayonet. Then turn it, and then reveal other card slots at the drop bayonet. Therefore, when the detection card 93 can balance the weight distribution on the bracket 65, or when the detection card and the trim card can balance the weight distribution on the bracket 65, a card position can be revealed at the bayonet drop to guide the user to carry out Test card placement. Then complete the multi-throughput centrifugation platform such as molecular diagnostic equipment 100 to assist users in Cato The process of placing the test card 93 on the 65.
  • this method can assist manual placement of the detection card 93 , thereby reducing the error rate of manual placement of the detection card, and also solving the problem of a large amount of noise generated by a multi-throughput centrifugation platform such as the molecular diagnostic device 100 during centrifugation.
  • the multi-throughput centrifugal platform such as molecular diagnostic equipment 100 can determine the number and position of the required card positions according to the number of test cards, and then further determine the number and position of the required card positions.
  • a preset algorithm is used to perform a trim calculation on the number of detection cards and the number of card slots on the card tray to obtain a strategy.
  • the preset algorithm can be set in a system of a multi-throughput centrifugation platform such as the molecular diagnostic device 100 .
  • the strategy can also be pre-corresponded to the number of test cards and preset in the system of the multi-throughput centrifugation platform such as molecular diagnostic equipment 100, so that when the number of test cards is obtained, the pre-correspondence search can be performed , and then get the strategy.
  • the strategy may include that the card tray is rotated so that the positions of the required card positions are sequentially revealed, so that the cards such as the detection card and the trim card are placed on the card positions revealed at the bayonet drop.
  • the strategy may also include the direction in which the tray rotates, such as clockwise or counterclockwise.
  • the strategy may include reminding the user to place a detection card or a trim card on the card position by means of an indicator light, voice, etc. when the card position is revealed at the drop bayonet. For example, if the detection card is placed at the checkpoint, the user will be reminded to place the detection card through voice broadcast. For example, if a trim card is placed at the drop bayonet, the indicator light will flash to remind the user to place the trim card.
  • Step S2202 Control the card tray to rotate according to the strategy, and reveal the card position of the card tray at the bayonet drop.
  • the card support can be controlled to rotate according to the strategy, so that the positions of the required card positions are sequentially revealed at the bayonet drop.
  • the user only needs to place the detection card or the trim card to complete the trim when the card position is revealed at the drop bayonet, which ensures the safe operation of the multi-throughput centrifugal platform such as the molecular diagnostic device 100 .
  • FIG. 23 is a flowchart of a control method based on a multi-throughput centrifugal platform in another embodiment of the present application. Before step S2202, the method also includes:
  • Step S2301 Determine the previous working mode instruction for controlling the work of the multi-throughput centrifugal platform.
  • the working mode commands of a multi-throughput centrifugal platform such as the molecular diagnostic apparatus 100 may include a mode command requiring a trim card for trimming and a mode command not requiring a trim card for trimming.
  • the two working mode commands have their own characteristics.
  • a mode instruction requiring a trim card for trimming will generate a strategy that requires the participation of a trim card when the check card is trimmed, and the trim card will not be taken out when the check card check is completed.
  • the mode instruction that does not require a trim card to perform trimming will generate a strategy based on the detection card first when the detection card is trimmed, and generate a strategy that requires the participation of the trim card when the detection card cannot complete the balance. When the testing of the testing card is completed, take out the trim card.
  • the setting of the two working mode commands can allow the user to choose according to the needs, so as to better improve the detection efficiency.
  • the working mode instructions of the multi-throughput centrifugal platform such as the molecular diagnostic device 100 can be input through input devices such as a display, a keyboard, and a code scanning device 14 to control the multi-throughput centrifugal platform such as the molecular diagnostic device 100 . It can be understood that the working mode instructions of the multi-throughput centrifugation platform such as the molecular diagnostic device 100 may also include other working mode instructions, which will not be repeated here.
  • the previous work mode instruction for controlling the work of the multi-flux centrifugal platform will make the user consider whether there is a trim card in the card tray during the current detection card detection, whether the current detection card needs the trim card to participate in the trimming, and whether the trim card is taken and placed.
  • step S2202 may include:
  • Step S2302 Combining the number of detection cards and the previous working mode instruction for controlling the work of the multi-throughput centrifugal platform, a strategy is obtained.
  • the last working mode command controlling the work of the multi-flux centrifugal platform will leave a trim card on the tray, it is necessary to consider the card tray based on the previous working mode command controlling the work of the multi-flux centrifugal platform when generating the strategy. Is there a trim card problem.
  • the previous working mode instruction for controlling the work of the multi-flux centrifugal platform is a mode instruction requiring a trim card for trimming, then there is a trim card on the current card tray.
  • the previous working mode instruction for controlling the work of the multi-flux centrifugal platform is a mode instruction that does not require a trim card for trimming, then there is no trim card on the current card tray.
  • the trim card when there is a trim card in the current tray, the trim card can be taken out first, and then the current working mode instruction for controlling the work of the multi-flux centrifugal platform is executed, that is, a strategy is generated according to the number of detection cards.
  • a strategy that requires the participation of the trim card when there is a trim card in the current tray, can be directly generated, so as to reduce the steps of removing the trim card and improve detection efficiency.
  • the trim card if there is a trim card in the current tray, and a strategy that requires the participation of the trim card cannot be directly generated, the trim card can be taken out to generate a strategy that does not require the participation of the trim card. In order to improve the intelligence of the multi-throughput centrifugal platform such as the molecular diagnostic device 100 .
  • step S2301 can be performed simultaneously with step S2201, or step S2301 can be performed first, and then step S2201 can be performed, or step S2201 can be performed first, and then step S2301 can be performed.
  • Step S2301 may include: determining that the previous working mode instruction for controlling the operation of the multi-throughput centrifugal platform is a mode instruction requiring a trim card for trimming.
  • Step S2302 may include:
  • Step S2401 Obtain the sum of the number of detection cards and the number of trim cards in the cassette.
  • the previous working mode instruction for controlling the work of the multi-flux centrifugal platform is a mode instruction requiring a trim card for trimming, so the current card holder is placed with a trim card. Therefore, if the trim card is taken out before the current working mode command controlling the work of the multi-flux centrifugal platform is executed, the trim card will be put in again because the current working mode command controlling the work of the multi-flux centrifugal platform requires a trim card, which will lead to the operation steps It is cumbersome and reduces the detection efficiency. In order to improve the detection efficiency, the trim card may not be removed when the detection can be completed without taking out the trim card.
  • Step S2402 Obtain the policy according to the sum of the quantity and the number of card slots of the tray.
  • the corresponding strategy can be obtained according to the quantity.
  • This strategy can be a strategy that requires the participation of a trim card, or a strategy that does not require the participation of a trim card.
  • the balance in response to the result that the balance cannot be achieved according to the sum of the numbers and the number of card slots of the card tray, the balance can be directly performed based on the number of detected cards to obtain a strategy.
  • the card slot for placing the trim card in response to the result that the trim cannot be balanced according to the number and the number of card slots of the card tray, the card slot for placing the trim card is revealed at the drop bayonet, so that the user can take out the trim card, and execute the strategy to detect the card Placement on Cato.
  • the current working mode command for controlling the operation of the multi-flux centrifugal platform is recorded as a mode command that does not require a trim card for trimming. Since it cannot be trimmed, the trim card must be removed. If the current working mode command that controls the work of the multi-flux centrifugal platform is a mode command that requires a trim card to be trimmed, then after the test is completed, the trim card does not have a trim card, which will cause a system error, which will cause the next test card to be trimmed. .
  • the working mode command currently controlling the work of the multi-flux centrifugal platform can be changed to a mode command that does not require a trim card for trimming, so that the next test card trimming can be carried out smoothly.
  • a card position can be revealed at the drop bayonet, so that the user can place the trim card, so that the current working mode command for controlling the work of the multi-flux centrifugal platform is still the mode command that requires the trim card for trimming , and the next test card balance can be carried out smoothly.
  • step S2402 may include, in response to the result that the balance can be achieved according to the sum of the quantity and the number of the card slots of the card tray, performing a balance based on the quantity and the number of the card slots of the card tray to obtain a strategy.
  • Step S2203 may include: in response to the fact that the initial position of the card position corresponding to the trim card is not at the drop bayonet, controlling the card support to rotate according to a strategy to jump the corresponding trim card position over the drop bayonet, revealing the space of the card holder at the drop bayonet. card position.
  • this slot can be the slot where the trim card is placed, and then it can be rotated according to a strategy to reveal other required slots for placing the detection card on the card tray.
  • the card position is an empty card position, it means that the trim card is placed in other positions and can be rotated according to the strategy, because there is a trim card placed in a required card position, and the trim card does not need to be taken out, so, that is The card position corresponding to the trim card can be skipped at the drop bayonet to reveal other required card positions, thereby improving the detection efficiency and avoiding the wrong operation of the user taking out the test card.
  • step S2301 may include: determining that the previous working mode command for controlling the operation of the multi-throughput centrifugal platform is a mode command that does not require a trim card for trimming.
  • Step S2302 may include: combining the number of detected cards and the number of slots of the tray to obtain a strategy.
  • the strategy can be obtained by performing trimming only based on the number of detection cards and the number of card slots in the tray.
  • the obtained strategy may be a strategy that does not require the participation of the trim card, or may be a strategy that requires the participation of the trim card. That is, in response to the result that the balance cannot be balanced according to the number of detected cards and the number of card slots of the tray, the trim card is used for trimming to obtain a strategy.
  • FIG. 25 is a flowchart of a control method based on a multi-throughput centrifugal platform in another embodiment of the present application.
  • the method may also include:
  • Step S2501 Determine that the current working mode instruction for controlling the operation of the multi-flux centrifugal platform is a mode instruction requiring trimming by a trim card.
  • step S2203 the method also includes:
  • Step S2502 Rotate the position of the corresponding trim card in the tray to a designated position for reset.
  • the current working mode instruction for controlling the work of the multi-flux centrifugal platform is a mode instruction that requires a trim card for trimming. After the detection card detection is completed, the trim card needs to be kept on the card holder. Therefore, it is necessary to reset the trim card, so that the next card trim operation can be performed smoothly, and the detection efficiency can be improved.
  • the designated position can be that when the card tray 93 slides to the side of the code scanning device 14, a card position will be revealed at the bayonet drop. Of course, considering the trimming effect, the designated position may also be a card position opposite to the card tray 93 sliding toward the code scanning device 14 to reveal the card position at the drop bayonet. Of course, other card positions can also be used, for example, the card position without the trim card in the tray is rotated to a position corresponding to the bayonet drop.
  • step S2501 may be the same step as step S2301, or may not be the same step.
  • the user when the card position is revealed at the bayonet opening, the user can be reminded to place the detection card or trim card on the card position through the indicator light, voice, etc. according to the strategy, and the user can also be reminded to take out the detection card or balance card. Card.
  • the drop card When placing a card such as a detection card or a balance card at the mouth, the code scanning device can be turned on to obtain information, and judge whether the imitation card type is correct, and can remind the user in the card position through indicator lights and voice according to the strategy when it is incorrect. Place the detection card or trim card on the screen, or remind you that the card is wrongly placed.
  • FIG. 26 is a schematic structural diagram of a multi-throughput centrifugal platform in an embodiment of the present application.
  • the multi-throughput centrifugal platform 97 includes:
  • An acquisition module 971 configured to acquire the number of test cards
  • a determination module 972 configured to determine the card tray rotation strategy of the multi-throughput centrifugal platform corresponding to the number of detection cards
  • the control module 973 is used to control the rotation of the card tray according to the strategy, and reveal the card position of the card tray at the bayonet drop.
  • the determining module 972 is configured to use a preset algorithm to perform a trim calculation on the number of detected cards and the number of card slots on the card tray to obtain a strategy.
  • the determination module 972 before the determination module 972 determines the card tray rotation strategy of the multi-throughput centrifugal platform corresponding to the number of detection cards, the determination module 972 is used to determine the previous working mode instruction for controlling the work of the multi-throughput centrifugal platform, the working mode The command is a mode command that requires a trim card for trimming, or a mode command that does not require a trim card for trimming. Further, the determination module 972 is used to combine the number of detection cards and the previous working mode instruction for controlling the work of the multi-throughput centrifugal platform to obtain a strategy.
  • the determining module 972 is configured to determine that the previous working mode instruction for controlling the operation of the multi-throughput centrifugal platform is a mode instruction requiring a trim card for trimming. Further, the determination module 972 is used to obtain the sum of the number of detection cards and the number of trim cards in the tray, and obtain a strategy according to the sum of the numbers and the number of card slots in the tray. In some embodiments, the determining module 972 is configured to directly use the number of detected cards for balancing to obtain a strategy in response to the result that the balance cannot be achieved according to the sum of the numbers and the number of card slots of the card tray.
  • control module 973 is configured to reveal the position where the trim card is placed at the bayonet drop in response to the result that the balance cannot be achieved according to the sum of the number and the number of the positions of the card tray. In some embodiments, the control module 973 is configured to record the current working mode instruction for controlling the work of the multi-flux centrifugal platform as not needing the trim card for trimming in response to the result that the trimming cannot be performed according to the sum of the numbers and the number of the card slots. mode directive.
  • the determining module 972 is configured to perform a balance based on the quantity sum and the number of card slots of the card tray to obtain a policy in response to the result of balancing the number and the number of card slots.
  • the control module 973 is configured to respond to the fact that the initial position of the card position corresponding to the trim card is not at the drop bayonet, and control the card support to rotate according to the strategy so as to jump the corresponding trim card position over the drop bayonet, and reveal the card at the drop bayonet Empty card slots.
  • the determination module 972 is configured to determine that the previous working mode command for controlling the operation of the multi-throughput centrifugal platform is a mode command that does not require a trim card for trimming. Further, the determining module 972 is used to combine the number of detected cards and the number of slots of the tray to obtain a strategy. In some embodiments, the determining module 972 is configured to perform trimming with the trimming card to obtain a strategy in response to the result that the trimming cannot be performed according to the detected number of cards and the number of card slots of the card tray.
  • the determination module 972 is used to determine that the current working mode instruction for controlling the work of the multi-flux centrifugal platform is required
  • the trim card is the mode command for trimming.
  • the control module 973 is used to rotate the corresponding trim card's position in the card holder to a designated position for reset. In some embodiments, the control module 973 is used to rotate the card position in the card holder without the trim card to the card drop slot, so as to complete the reset.
  • FIG. 27 is a schematic framework diagram of a computer-readable storage medium according to an embodiment of the present application.
  • the computer-readable storage medium 98 stores a computer program 981.
  • the computer program 981 is executed by the processor, the automatic balancing method based on the multi-throughput centrifugal platform in the above detection card placement process is implemented.
  • the computer-readable storage medium 98 can specifically be a U disk, a mobile hard disk, a read-only memory (ROM, Read-Only Memory), a random access memory (RAM, Random Access Memory), a magnetic disk or an optical disk, etc., which can store program instructions. media, or a server that stores the program instructions, and the server can send the stored program instructions to other devices for execution, or can also run the stored program instructions by itself.
  • a unit described as a separate component may or may not be physically separated, and a component displayed as a unit may or may not be a physical unit, that is, it may be located in one place, or may be distributed to multiple network units. Part or all of the units can be selected according to actual needs to achieve the purpose of the solution of this embodiment.
  • each functional unit in each embodiment of the present application may be integrated into one processing unit, each unit may exist separately physically, or two or more units may be integrated into one unit.
  • the above-mentioned integrated units can be implemented in the form of hardware or in the form of software functional units.

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Abstract

本申请提供了一种控制方法、多通量离心平台及计算机可读存储介质，涉及分子检测技术领域。该方法包括：获取检测卡数量；确定对应所述检测卡数量的所述多通量离心平台的卡托旋转策略；控制所述卡托按照所述策略旋转，在落卡口处显露所述卡托的卡位。本申请通过检测卡数量，确定对应检测卡配平结果的旋转策略，进而通过旋转，使得卡位在落卡口显露，来引导用户在落卡口处的卡位上放置检测卡，进而实现了检测卡的配平，降低离心处理时因检测卡放置不合理引起的噪音，另外，本申请中多通量离心平台按上述方法运行实现配平，无需用户过多参与配平，也无需用户担忧配平效果而更加智能。

Description

控制方法、多通量离心平台及计算机可读存储介质
本申请请求2022年02月25日申请的，申请号为2022101780043，发明名称为“控制方法、多通量离心平台及计算机可读存储介质”的中国发明专利申请的优先权。
【技术领域】
本申请涉及分子检测技术领域，具体涉及一种控制方法、多通量离心平台及计算机可读存储介质。
【背景技术】
对于分子诊断设备，其利用了分子诊断技术。对于分子诊断技术是指利用核酸或蛋白质作为生物标记进行临床检测的诊断技术，为疾病的预测、诊断、预防、治疗和转归提供了信息和决策依据。
在分子诊断设备对检测卡进行检测时，需要事先对检测卡进行离心处理，在某些情况下，检测卡数量不足以在卡托上分布均匀，进而在离心处理时产生噪音。
【发明内容】
本申请一个方面提供一种基于多通量离心平台的控制方法，包括：
获取检测卡数量；
确定对应所述检测卡数量的所述多通量离心平台的卡托旋转策略；
控制所述卡托按照所述策略旋转，在落卡口处显露所述卡托的卡位。
在另一方面，本申请还提供一种基于多通量离心平台，包括：
获取模块，用于获取检测卡数量；
确定模块，用于确定对应所述检测卡数量的所述多通量离心平台的卡托旋转策略；
控制模块，用于控制所述卡托按照所述策略旋转，在落卡口处显露所述卡托的卡位。
在另一方面，本申请还提供一种计算机可读存储介质，其上存储有计算机程序，所述计算机程序被处理器执行时实现如上述任一项所述的方法。
【附图说明】
为了更清楚地说明本申请实施例中的技术方案，下面将对实施例中所需要使用的附图作简单的介绍。显而易见地，下面描述中的附图仅仅是本申请的一些实施例，对于本领域普通技术人员来讲，在不付出创造性劳动的前提下，还可以根据这些附图获得其他的附图。
图1为本申请一实施例中分子诊断设备的立体结构示意图；
图2为图1中分子诊断设备的爆炸分解图；
图3为图2中抵压盘的爆炸示意图；
图4和图5分别为图3中第一壳体不同视角的结构示意图；
图6为图3中抵压盘的结构示意图；
图7为图2中机架与抵压盘的连接结构示意图；
图8为图2中托运组件的结构示意图；
图9为图8中托运件的结构示意图；
图10和图11分别为图2中抵压盘和托运组件配合下不同视角的结构示意图；
图12为图2中检测卡检测座的爆炸图；
图13为图12中支撑座的爆炸图；
图14为图13中支撑座主体的结构示意图；
图15为图13中光检测件的结构示意图；
图16为图13中加样腔组件的结构示意图；
图17为图12中光发生器的结构示意图；
图18为本申请一实施例中检测卡的结构示意图；
图19为图18中检测卡沿线L-L的剖面图；
图20为图18中检测卡的立体结构示意图；
图21为图20中检测卡使用过程示意图；
图22为本申请中一实施例中基于多通量离心平台的控制方法流程图；
图23为本申请中另一实施例中基于多通量离心平台的控制方法流程图；
图24为本申请中另一实施例中基于多通量离心平台的控制方法流程图；
图25为本申请中另一实施例中基于多通量离心平台的控制方法流程图；
图26为本申请一实施例中多通量离心平台的结构示意图；
图27为本申请中一实施例的一种计算机可读存储介质的框架示意图。
【具体实施方式】
下面将结合本申请实施例中的附图，对本申请实施例中的技术方案进行清楚、完整地描述。显然，所描述的实施例仅是本申请一部分实施例，而不是全部的实施例。基于本申请中的实施例，本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例，都属于本申请保护的范围。
在本文中提及“实施例”意味着，结合实施例描述的特定特征、结构或特性可以包含在本申请的至少一个实施例中。在说明书中的各个位置出现该短语并不一定均是指相同的实施例，也不是与其他实施例互斥的独立的或备选的实施例。本领域技术人员显式地和隐式地理解的是，本文所描述的实施例可以与其他实施例相结合。
接下来阐述一种分子诊断设备，其利用了分子诊断技术。对于分子诊断技术是指利用核酸或蛋白质作为生物标记进行临床检测的诊断技术，为疾病的预测、诊断、预防、治疗和转归提供了信息和决策依据。特别是面对各种突发性传染性疾病，其最经济有效的措施就是快速、准确的分子诊断。
请参阅图1和图2，图1为本申请一实施例中分子诊断设备100的立体结构示意图，图2为图1中分子诊断设备100的爆炸分解图。分子诊断设备100可包括机架10、安装在机架10上的检测卡输送座20、安装在机架10上的检测卡检测座30以及安装在机架10上的控制电路板40。
其中，检测卡输送座20可用于放置检测卡。检测卡输送座20可相对于机架10滑动，以使检测卡输送座20托运检测卡并托运至检测卡检测座30上。检测卡检测座30用于产生激发光，以对检测卡进行检测并形成检测信号。控制电路板40可用于控制检测卡输送座20在机架10上的滑动，并控制检测卡检测座30对检测卡进行检测，以及接收检测信号并对检测信号进行处理形成诊断数据。
在一些实施例中，分子诊断设备100还可包括可与控制电路板40电连接的显示器、键盘、扫码设备14(图2所示)等输入设备，以通过输入设备向分子诊断设备100例如控制电路板40输入控制指令，实现分子诊断设备100通过控制电路板40对检测卡输送座20和/或检测卡检测座30的控制
请参阅图2，机架10可包括机架主体11、安装在机架主体11上的第一驱动组件12以及安装在机架主体11上的丝杠13。其中，机架主体11用于安装检测卡输送座20、检测卡检测座30和控制电路板40等结构。第一驱动组件12用于与控制电路板40电连接，以接受控制电路板40的控制。第一驱动组件12在控制电路板40的控制下驱动丝杠13转动。丝杠13与检测卡输送座20转动连接，以在第一驱动组件12的驱动下，使得检测卡输送座20相对于机架主体11在丝杠13的延伸方向上滑动，实现对检测卡的托运。
机架主体11整体可呈框架结构。机架主体11内部可用于安装检测卡输送座20和检测卡检测座30，且检测卡输送座20位于检测卡检测座30的上方。当然，在一些实施例中，检测卡输送座20与检测卡检测座30分别在机架主体11的安装位置还可以是其他，不做赘述。
在本文中，可能采用“上”“下”“前”“后”“左”“右”“顶部”“底部”“上部”“下部”这些方位来进行描述。需要理解的是，在本文中的术语“中心”“纵向”“横向”“长度”“宽度”“厚度”“上”“下”“前”“后”“左”“右”“竖直”“水平”“顶”“底”“内”“外”“顺时针”“逆时针”“轴向”“径向”“周向”等指示的方位或位置关系为基于附图所示的方位或位置关系，仅是为了便于描述本申请和简化描述，而不是指示或暗示所指的装置或元件必须具有特定的方位、以特定的方位构造和操作，因此不能理解为对本申请的限制。
机架主体11上设置有第一导轨111。第一导轨111可用于安装检测卡输送座20，以使得检测卡输送座20在第一导轨111上滑动，并在第一导轨111的延伸方向上滑动。在一实施例中，第一导轨111的延伸方向可为竖直方向。
需要指出的是，在本文中的术语“第一”“第二”等仅用于描述目的，而不能理解为指示或暗示相对重要性或者隐含指明所指示的技术特征的数量。由此，限定有“第一”“第二”的特征可以明示或者隐含地可包括一个或者更多个所述特征。
丝杠13可安装在机架主体11上。丝杠13在第一驱动组件12的驱动下可推动检测卡输送座20在机架主体11例如第一导轨111上滑动，实现检测卡输送座20托运检测卡的效果。在一些实施例中，丝杠13的延伸方向可与第一导轨111的延伸方向相同。
机架10例如机架主体11上设置有与控制电路板40电连接的扫码设备14。扫码设备14可用于对检测卡上的信息标识例如二维码、条形码等进行图像扫描，并将图像传输至控制电路板40。控制电路板40 对图像进行识别、获取检测卡的相关信息。扫码设备14可设置在检测卡输送座20相对于机架10滑动的路径上，以在将检测卡放置在检测卡输送座20上时，检测卡上的信息标识被扫码设备14进行图像扫描。
请参阅图2，检测卡输送座20可包括安装在机架10例如第一导轨111上的抵压盘50及托运组件60。其中，托运组件60用于放置检测卡。抵压盘50与丝杠13螺纹连接，以在第一驱动组件12的作用下，在第一导轨111上滑动，进而带动托运组件60在第一导轨111上滑动，托运组件60可托运检测卡并托运至检测卡检测座30上。
请参阅图3，图3为图2中抵压盘50的爆炸示意图。抵压盘50可包括安装在机架10例如丝杠13上的第一壳体51、设置在第一壳体51朝向检测卡检测座30一侧的电磁件52、用于对托运组件60上的检测卡进行固定的压紧件53、设置在第一壳体51上的第一加热件54及第二加热件55、安装在第一壳体51上且分别与电磁件52和第一加热件54及第二加热件55电连接的第一电路板56、盖设在第一壳体51远离电磁件52一侧的第二壳体57以及设置在第一壳体51上且安装在机架10例如第一导轨111上的第一滑轨58。
其中，第一壳体51和第二壳体57扣合形成抵压盘主体。第一电路板56可与控制电路板40电连接。电磁件52可在控制电路板40的控制下产生磁作用力，以将压紧件53吸附在第一壳体51上。电磁件52可在控制电路板40的控制下消除磁作用力，以避免对压紧件53进行吸附。第一加热件54及第二加热件55可在控制电路板40的控制下对检测卡进行加热。第一滑轨58可在机架10例如第一导轨111上滑动。第一壳体51与机架10例如丝杠13连接，以在丝杠13的转动下在第一导轨111的延伸方向上滑动。
请参阅图4和图5，图4和图5分别为图3中第一壳体51不同视角的结构示意图。第一壳体51可采用硬性材料例如塑料、金属等制成。第一壳体51可呈板状结构，当然也可以为其他形状，不作赘述。第一壳体51可包括壳体主体511。壳体主体511朝向第二壳体57一侧的中部设置有容纳槽512，以用于容纳第一电路板56。容纳槽512的截面可呈圆形，也可以为其他形状。
壳体主体511在容纳槽512的周围可设置卡接孔513，以用于安装第一加热件54。卡接孔513可圆周均布在容纳槽512的周围。卡接孔513的数量可为1个或多个。在一些实施例中，卡接孔513的数量也可为2、3、4、5、6……中的一个。在一实施例中，卡接孔513的数量可具体为6个。在一实施例中。卡接孔513的形状为环状结构的一段。
壳体主体511设置有豁口514，以对托运组件60让位。豁口514自壳体主体511靠近扫码设备14一侧的边缘向内部延伸设置。在一实施例中，豁口514位于相邻两个卡接孔513之间。
壳体主体511在靠近丝杠13的部位设置螺接部515。螺接部515可套设在丝杠13上。螺接部515内部设置有与丝杠13的外螺纹配合的内螺纹，以在丝杠13的转动下，使得壳体主体511在丝杠13的延伸方向移动。
壳体主体511远离第二壳体57一侧表面的中部可用于连接电磁件52和压紧件53、第二加热件55。在一实施例中，壳体主体511在远离第二壳体57一侧表面的中部圆周均布多个容置槽516，以用于安装电磁件52。容置槽516的数量可为多个，具体数量可为2、3、4、5、6等中的一个。在一实施例中，容置槽516的数量可为2个。
请再次参阅图3，电磁件52可通电产生磁作用力，进而对压紧件53进行吸附固定。电磁件52与第一电路板56电连接，数量可为两个，其中一个电磁件52可安装在一个容置槽516内。具体地，电磁件52可通过螺接、卡接、插接、焊接、粘接等连接方式固定在壳体主体511上。
请再次参阅图5，压紧件53可采用硬性材料例如金属等制成，具体可为被电磁铁在磁作用力下吸附的金属例如铁等制成。当然，在某些实施例中，每一个压紧件53也可采用硬性材料例如塑料、金属等制成。在电磁件52对压紧件53吸附时，电磁件52可以吸附压紧件53。
请再次参阅图3，第一加热件54安装在第一壳体51例如壳体主体511靠近第二壳体57一侧。第一加热件54内部可设置加热电阻等发热器件。第一加热件54的数量可为多个，具体数量可为2、3、4、5、6等中的一个。在一实施例中，第一加热件54的数量可与卡接孔513的数量一致，可为6个。
第一加热件54可置于第一壳体51例如卡接孔513内，与第一壳体51例如壳体主体511卡接，以实现第一加热件54在第一壳体51上的安装。
在一些实施例中，第一加热件54与第一电路板56电连接，以实现对第一加热件54内部发热器件的控制。
请再次参阅图3，第二加热件55安装在第一壳体51例如壳体主体511远离第二壳体57一侧。第二加热件55整体可为环形结构。第二加热件55可采用可导热的硬性材料例如金属制成，内部可设置加热电阻等发热器件。第二加热件55安装在壳体主体511远离第二壳体57的一侧。第二加热件55可通过螺接、插接、卡扣等连接方式固定在让位槽517上。在一些实施例中，第二加热件55内部发热器件与第一电路板56电连接，以实现对第二加热件55内部发热器件的控制。
请再次参阅图3，第一电路板56整体可为环形结构。第一电路板56上设置有电阻、电容、电感等电子元器件。第一电路板56安装在壳体主体511的容纳槽512内。第一电路板56可分别与第一加热件54内的发热器件、第二加热件55内的发热器件、电磁件52电连接，以便对第一加热件54内的发热器件、第二加热件55内的发热器件和电磁件52分别进行控制。
请参阅图6，图6为图3中抵压盘50的结构示意图。第二壳体57可包括可与第一壳体51例如壳体主体511扣合的盖体主体571。其中，盖体主体571可与第一壳体51例如壳体主体511采用螺接、插接、卡扣、焊接、粘接等连接方式连接固定，不做赘述。
盖体主体571可采用硬性材料例如塑料、金属等制成。盖体主体571设置有贯穿孔572。贯穿孔572可与容纳槽512相对设置，以对第一电路板56让位，使得第一电路板56裸露在外。在一实施例中，贯穿孔572可以省略，盖体主体571完全覆盖在第一壳体51例如壳体主体511上。
盖体主体571设置有豁口573。豁口573自盖体主体571的边缘向内延伸设置以与贯穿孔572连通。豁口573设置在盖体主体571上与豁口514相对的位置，以在盖体主体571与壳体主体511扣合时，豁口573与豁口514连通，以对托运组件60让位，使得托运组件60可在豁口573与豁口514内滑动。
盖体主体571在远离第一壳体51的一侧设置有挂耳574，以与托运组件60连接。挂耳574采用螺接、插接、卡扣、焊接、粘接等连接方式连接固定在盖体主体571上。
请再次参阅图6，第一滑轨58设置在第一壳体51上，以实现第一壳体51与机架10例如第一导轨111的滑动连接。
请参阅图7，图7为图2中机架10与抵压盘50的连接结构示意图。抵压盘50安装在机架10上。其中，第一滑轨58安装在机架主体11上的第一导轨111上。螺接部515与丝杠13螺接。可在第一驱动组件12运动时，带动丝杠13同步运动，进而丝杠13均与抵压盘50相对转动，以使抵压盘50的第一滑轨58可在第一导轨111上滑动，实现了抵压盘50的位置移动，具体地是实现了抵压盘50在竖直方向上的位置移动。
请参阅图8，图8为图2中托运组件60的结构示意图。托运组件60可包括设置在抵压盘50上方且安装在机架10例如第一导轨111上的滑动架61以及安装在滑动架61上的托运件62。其中，滑动架61可在机架10例如第一导轨111上滑动。滑动架61与抵压盘50连接，以在某些情景中与抵压盘50一同在机架10上滑动。托运件62可用于放置检测卡。托运件62可相对于滑动架61滑动。托运件62相对于滑动架61的滑动方向与滑动架61相对于机架10的滑动方向不同。
可以理解地，托运组件60在伸展时，托运件62在滑动架61上滑动，以滑动至机架10外的第一位置，完成伸展，在托运组件60处于伸展状态时放置检测卡。然后，托运组件60在收缩时，托运件62在滑动架61上滑动，以滑动至机架10内的第二位置，完成收缩，在托运组件60处于收缩状态时可在第一导轨111上的第三位置和第四位置之间滑动。在一些实施例中，托运组件60可在第三位置时进行伸展。在一些实施例中，托运组件60可在第三位置与第四位置之间的位置进行伸展。
滑动架61可包括固定架611、安装在固定架611上且与机架10例如第一导轨111滑动连接的第二滑轨612、安装在固定架611上且用于安装托运件62的第二导轨613以及用于驱动托运件62在第二导轨613上滑动的驱动装置614。
固定架611可采用硬性材料例如塑料、金属等制成。固定架611整体可呈框架结构，当然也可以为其他形状，不做赘述。
第二滑轨612设置在固定架611上，用于在第二滑轨612与机架10例如第一导轨111滑动连接时实现固定架611与机架10的滑动连接。
第二导轨613安装在固定架611上，用于安装托运件62，使得托运件62在第二导轨613上滑动。第二导轨613的延伸方向可与豁口514的延伸方向一致，以便托运件62在第二导轨613上滑动的同时也在豁口514内滑动。
驱动装置614可包括设置在固定架611上的第二驱动组件6141以及与第二驱动组件6141连接的丝杠6142。其中，第二驱动组件6141用于驱动丝杠6142转动。第二驱动组件6141可通过螺钉、螺栓、卡扣、插接、焊接、粘接等连接方式连接固定在固定架611。第二驱动组件6141可与控制电路板40电连接，以在控制电路板40的控制下运动。丝杠6142与固定架611转动连接。丝杠6142的延伸方向可与第二导轨613的延伸方向一致。丝杠6142的外表面设置有外螺纹。丝杠6142通过外螺纹与托运件62螺接，以在丝杠6142转动时，丝杠6142与托运件62相对转动，在丝杠6142与第二导轨613的配合下使得托运件62在第二导轨613上滑动。在一实施例中，第二驱动组件6141可为电机。
在一些实施例中，为了实现抵压盘50与滑动架61一同滑动，可在固定架611上设置牵引件615。牵引件615可包括拉簧，例如，拉簧的一端与固定架611连接，另一端与挂耳574连接。
请参阅图9，图9为图8中托运件62的结构示意图。托运件62可包括安装在第二导轨613上且与驱 动装置614例如丝杠6142螺接的滑动座63、安装在滑动座63上的第三驱动组件64以及安装在第三驱动组件64上且可被第三驱动组件64驱动做旋转运动的卡托65。其中，滑动座63在第二导轨613上滑动，以在驱动装置614的驱动下，与丝杠6142相对转动，带动第三驱动组件64、卡托65一起移动，可移动至在机架10外的位置，以在卡托65上放置检测卡，滑动座63也可带动第三驱动组件64、卡托65移动至位于机架10内的位置，第三驱动组件64可带动卡托65上的检测卡做离心运动以完成检测卡的离心处理。
第三驱动组件64具体可通过螺接、插接、卡扣、焊接、粘接等方式与滑动座63连接固定。第三驱动组件64可为电机。电机的输出轴可与卡托65连接固定。
卡托65置于滑动座63的下方，与第三驱动组件64连接固定。卡托65可包括卡托主体651。卡托主体651可采用硬性材料例如塑料、金属等制成。卡托主体651呈回转体，回转体的轴心与第三驱动组件64的输出轴同轴设置。在一实施例中，卡托主体651为圆形盘状结构。
卡托主体651在靠近第三驱动组件64一侧设置凸筋652。凸筋652以卡托主体651与第三驱动组件64连接的部位为中心朝四周发散设置。凸筋652圆周均布在卡托主体651与第三驱动组件64连接的部位的周围。
相邻两个凸筋652与卡托主体651围设形成凹陷部653，以用于放置检测卡。凹陷部653的数量可与第一加热件54的数量一致。当然凹陷部653的数量也可以比第一加热件54的数量少。在一实施例中，凹陷部653的数量可为6个，当然凹陷部653的具体数量也可以根据实际情况进行调整。
卡托主体651在凹陷部653内设置第一卡固部654，以便与检测卡卡固。第一卡固部654位于卡托主体651靠近边缘的位置。在一实施例中，第一卡固部654为凹槽或凸柱。卡托主体651在凹陷部653内设置容置孔655以对检测卡让位。在一实施例中，凹陷部653为凹槽，凹槽的深度可与检测卡的厚度相同，以便在将检测卡放置在凹陷部653时，检测卡的表面与凸筋652远离卡托主体651的表面平齐。
卡托主体651可在压紧件53与卡托主体651接触时与压紧件53卡接。卡托主体651与压紧件53的卡接配合关系可为凹槽与凸柱、插接结构、卡扣结构等来卡接结构。在一实施例中，为了进一步增强卡托主体651与压紧件53之间的配合关系，可在卡托主体651和/或凸筋652内部设置永久性磁铁或电磁铁等磁作用力连接件，以便利用磁作用力对压紧件53进行吸附，增强卡托主体651与压紧件53之间的配合关系，使得压紧件53可与检测卡的表面抵接，以避免检测卡安装不稳定。
在一实施例中，卡托主体651在远离第三驱动组件64的一侧设置有第一定位件656(如图10所示)，以便在将检测卡托运至检测卡检测座30时，实现对检测卡的定位，使得检测卡放置在预定位置，以进行检测卡检测。在一实施例中，第一定位件656为定位块，定位块向远离卡托主体651一侧延伸，且与延伸方向垂直的截面面积渐变且逐渐减小。在一实施例中，定位块可为圆锥形。
可以理解地，卡托主体651将检测卡托运至检测卡检测座30时，托运件62可位于第四位置。
请参阅图10和图11，图10和图11分别为图2中抵压盘50和托运组件60配合下不同视角的结构示意图。在抵压盘50与托运组件60连接时，先将托运组件60中除去卡托65的元件组装在一起，然后将托运组件60中的滑动架61置于抵压盘50的上方。滑动架61中的第二滑轨612与抵压盘50的第一滑轨58相对设置以便一同安装在机架10例如机架主体11的第一导轨111上。
可以理解地，抵压盘50和托运组件60也可以分别安装在不同的第一导轨111上。当然也可以部分第一导轨111仅安装抵压盘50或托运组件60。
接着，将托运组件60中托运件62的卡托65置于抵压盘50远离滑动架61的一侧，以使压紧件53位于第一壳体51与卡托65之间。托运组件60中托运件62的第三驱动组件64的输出轴穿过抵压盘50的豁口与卡托65连接固定。抵压盘50的挂耳574与托运组件60中的牵引件615相对设置并相互连接。
请参阅图12，其为图2中检测卡检测座30的爆炸图。检测卡检测座30可包括与机架10连接固定的支撑架70、安装在支撑架70上的支撑座80、安装在支撑架70和支撑座80上的检测组件90。其中，支撑座80位于抵压盘50的下方，以便于承载检测卡输送座20例如托运组件60输送来的检测卡。检测组件90与控制电路板40电连接。检测组件90在支撑座80上放置检测卡时，利用激发光对检测卡进行一系列的检测处理以生成检测信号，并将检测信号输送至控制电路板40。
请参阅图12，支撑架70整体呈框架结构，可位于机架10的底部。支撑架70可包括设置在机架10底部且与机架10连接固定的底座71以及安装在底座71顶部的固定座72。
请参阅图13，图13为图12中支撑座80的爆炸图。支撑座80可包括安装在底座71上的支撑座主体81、安装在支撑座主体81上的检测腔组件82、安装在支撑座主体81上且与检测腔组件82配合支撑检测卡的加样腔组件83以及设置在支撑座主体81上的第二电路板84。其中，检测腔组件82可安装在支撑座80上与第一加热件54相对的位置，以与第一加热件54配合。加样腔组件83可安装在支撑座80上与第二加热件55相对的位置，以与第二加热件55配合。检测腔组件82与加样腔组件83一同配合对检测卡进 行支撑及加热处理。检测腔组件82还可用于对检测卡进行激发光检测。检测腔组件82和加样腔组件83一同与第二电路板84电连接，以实现对检测腔组件82、加样腔组件83的加热控制。
请参阅图14，图14为图13中支撑座主体81的结构示意图。支撑座主体81可采用硬性材料例如塑料、金属等制成。支撑座主体81整体可呈板状结构。支撑座主体81的顶部可开设放置槽811，以对卡托65进行让位。
支撑座主体81在放置槽811内开设卡固孔812，以用于与加样腔组件83配合。支撑座主体81在放置槽811内还设置有第二定位件813，以与第一定位件656配合实现对检测卡位置的定位。在一实施例中，第二定位件813可为支撑座主体81在放置槽811内开设的定位槽，以用于在第一定位件656例如定位块置于第二定位件813例如定位槽内实现对检测卡位置的定位。在一实施例中，第二定位件813例如定位块的形状可与第一定位件656例如定位槽的形状相匹配。可以理解地，支撑座主体81与卡托65之间定位配合关系并不仅限于第二定位件813与第一定位件656的配合关系，其还可以为磁铁与磁铁之间磁作用力、电磁铁与电磁铁之间磁作用力等配合关系，当然还可以是其他配合关系，不做赘述。
支撑座主体81在放置槽811的周围圆周均布多个延伸槽814。延伸槽814与放置槽811相通，以使支撑座主体81在相邻两个延伸槽814之间形成装配台815，可将检测卡放置在装配台815上，延伸槽814对检测卡进行让位，以使装配台815对检测卡进行支撑、卡固。
支撑座主体81在装配台815的位置处设置容纳孔816，以便在容纳孔816内安装检测腔组件82。
请参阅图13，检测腔组件82安装在支撑座主体81例如容纳孔816内。检测腔组件82可包括至少一个光检测件821，光检测件821具体数量可为1、2、3、4、5、6……中的一个，以便在容纳孔816内安装检测腔组件82。
光检测件821可与一个第一加热件54相对应设置，以便两者配合对一个检测卡加热。请参阅图15，图15为图13中光检测件821的结构示意图。光检测件821可包括置于支撑座主体81例如容纳孔816内的检测座8211。检测座8211可采用硬性材料例如塑料、金属等制成。检测座8211朝向容纳孔816的一侧延伸设置以伸入容纳孔816内。检测座8211在支撑座主体81设置装配台815的一侧与装配台815的表面平齐，以提高支撑座80的外观表现力，以用于支撑检测卡。
检测座8211在延伸方向上设置激发光纤8212，以便激发光纤8212向检测卡发出光线例如激发光。检测座8211在与延伸方向呈夹角的位置设置接收光纤8213。接收光纤8213用于接收激发光纤8212发出的激发光以及由激发光照射检测卡形成的荧光。
检测座8211在设置激发光纤8212的一侧设置有加热件容置槽8211a，以用于安置加热电阻等发热器件。检测座8211可通过发热器件实现对检测卡的加热。加热件容置槽8211a内的发热器件可与第二电路板84电连接，以在第二电路板84的控制下实现加热。
检测座8211在靠近加样腔组件83的一侧设置有加热件容置槽8211b，以用于安置加热电阻等发热器件。检测座8211可通过发热器件实现对检测卡的加热。加热件容置槽8211b内的发热器件可与第二电路板84电连接，以在第二电路板84的控制下实现加热。
可以理解地，在检测座8211内设置有发热器件后，具有对检测卡进行加热的效果。所以检测座8211可被称为“第三加热件”。在一实施例中，检测座8211可与支撑座主体81为一体结构。
请参阅图16，图16为图13中加样腔组件83的结构示意图。加样腔组件83可包括固定在固定座72上的托板831以及安装在托板831上的加样腔安装座832。其中，加样腔安装座832用于固定检测卡，也用于对检测卡进行加热。加样腔安装座832与第二加热件55配合以对检测卡进行加热。
托板831可采用硬性材料例如塑料、金属等制成。整体可呈板状结构，当然也可以为其他结构，不做赘述。托板831可通过螺接、插接、粘接、焊接等方式固定在固定座72上。在一实施例中，托板831可通过螺接、插接、粘接、焊接等方式固定在固定座72上。在一实施例中托板831可以省略，加样腔安装座832可以直接与固定座72固定连接。在一实施例中，在固定座72省略时，可以将托板831固定在底座71上。
加样腔安装座832用于放置检测卡。加样腔安装座832可包括安装座本体8321。安装座本体8321整体可采用塑料或金属等硬性可导热材料制成。安装座本体8321用于置于支撑座主体81例如卡固孔812内。安装座本体8321远离托板831的一侧设置加样腔安置槽8322，以用于安装检测卡。
安装座本体8321开设有加热件容置槽8323，以便于容置加热电阻等发热器件，使得安装座本体8321可以为检测卡进行加热。发热器件可与第二电路板84电连接，以在第二电路板84的控制下进行加热。
可以理解地，在安装座本体8321内设置有发热器件后，具有对检测卡进行加热的效果。所以加样腔安装座832可被称为“第四加热件”。
对于“第一加热件”“第二加热件”“第三加热件”“第四加热件”“第五加热件”“第六加热件”以及“加热件”等名称，在一些实施例中可以相互转换。例如在一实施例中，将其他实施例中的“第一加热件”称为“第二加热件”，相应地，将其他实施例中的“第二加热件”称为“第一加热件”。
为了更好地对检测卡加热，避免加热后的水汽冷凝影响检测流程，提高检测精度。安装座本体8321在加样腔安置槽8322的一侧边缘设置有抵接部8324，以与检测卡抵接。在一实施例中，抵接部8324也可用于对检测卡进行定位。
请参阅图13，第二电路板84可分别与检测腔组件82中的发热器件、加样腔组件83中的发热器件电连接，以便控制发热器件进行加热。
第二电路板84可为环状结构，可套设在加样腔组件83的周围。第二电路板84可直接固定在支撑座主体81靠近支撑架70的一侧，例如可采用焊接、插接、卡扣、粘接、螺接等方式固定。在一实施例中，第二电路板84也可以直接固定在支撑架70例如固定座72上。在一实施例中，第二电路板84也可以直接固定在支撑架70例如底座71上。在一实施例中，第二电路板84也可以直接固定在加样腔组件83例如托板831上。
在一实施例中，第二电路板84可以在不为控制电路板40分担工作压力的情况下，可以省略，检测腔组件82中的发热器件、加样腔组件83中的发热器件可直接与控制电路板40电连接。
请参阅图12。检测组件90可包括安装在支撑架70例如底座71上的光发生器91、安装在支撑架70例如底座71上的光接收器92以及安装在支撑座80例如支撑座主体81上的检测腔组件82(即前面介绍过的支撑座80的检测腔组件82，该检测腔组件82可为支撑座80以及检测组件90共用的元件)。其中，光发生器91以及光接收器92均与控制电路板40电连接。光发生器91用于产生激发光，并可在控制电路板40的控制下产生激发光。激发光可传输至检测腔组件82对检测卡进行激发并生成荧光，荧光可被光接收器92接收，光接收器92可在控制电路板40的控制下生成检测信号。检测信号传输至控制电路板40并控制电路板40处理生成诊断数据。
请一同参阅图12和图17，图17为图12中光发生器91的结构示意图。光发生器91的数量可为1个或多个。光发生器91的数量具体可为2、3、4、5、6……中的一个。在一实施例中，光发生器91的数量可为2个，具体为第一光发生器911和第二光发生器912。
第一光发生器911和第二光发生器912均可固定在固定座72上，可采用插接、焊接、螺接、粘接、卡扣等方式固定在固定座72上。第一光发生器911及第二光发生器912的激发光输出端与激发光纤8212连通。
请参阅图12，光接收器92用于与接收光纤8213连接，以接收荧光，进而将受荧光触发生成的检测信号传输至控制电路板40。光接收器92呈圈状且布置在光发生器91的周围。光接收器92可包括光传感器例如光电二极管。光传感器例如光电二极管可受荧光照射生成电信号。
请再次参阅图1和图2，控制电路板40上可设置有处理器、存储器等电子元件。控制电路板40可包括固定在机架10例如机架主体11不同位置的第一子控制电路板41及第二子控制电路板42。其中，第一子控制电路板41与第二子控制电路板42电连接。
第一子控制电路板41可与机架10例如第一驱动组件12电连接，以便控制检测卡输送座20相对于机架10的滑动位置。
第一子控制电路板41可与抵压盘50例如第一电路板56电连接，以便控制电磁件52，对压紧件53进行磁作用力吸附，以便控制第一加热件54、第二加热件55，对检测卡进行加热。
第一子控制电路板41可与托运组件60例如第二驱动组件6141电连接，以便控制第三驱动组件64和卡托65一同相对于滑动架61滑动。
第一子控制电路板41可与托运组件60例如第三驱动组件64电连接，以便控制第三驱动组件64带动卡托65对检测卡进行离心处理。
第一子控制电路板41可与第二电路板84电连接，以间接地与检测腔组件82例如发热器件电连接，以便控制检测座8211，对检测卡进行加热。
第一子控制电路板41可与第二电路板84电连接，以间接地与加样腔组件83例如发热器件电连接，以便控制加样腔安装座832，对检测卡进行加热。
第一子控制电路板41可与检测组件90例如光发生器91电连接，以便控制光发生器91发出激发光。
第一子控制电路板41可与检测组件90例如光接收器92电连接，以便控制光接收器92接收荧光。
第二子控制电路板42可安装在机架10例如机架主体11的上方。在一实施例中，在分子诊断设备100设置机壳时，第二子控制电路板42可设置在机壳在机架主体11相对的位置处。
第二子控制电路板42可与显示器、键盘、扫码设备14等输入设备电连接，以通过输入设备向分子诊断设备100例如控制电路板40输入控制指令，实现分子诊断设备100通过控制电路板40对检测卡输送 座20和/或检测卡检测座30的控制。
在一实施例中，第二子控制电路板42与第一子控制电路板41可集成为一个控制电路板上。
接下来阐述一种检测卡，可以用于上述实施例中的分子诊断设备100中，以完成对检测卡上装载的样本进行检测，并进一步处理形成诊断数据。
请参阅图18，其为本申请一实施例中检测卡的结构示意图。检测卡93又被称为分子诊断离心检测卡或测试卡。检测卡93可包括设置有加样腔、流道、废液腔、隔离腔和检测腔的本体94、覆盖在本体94一侧的隔离层95以及盖设在本体94加样腔处的盖体96。
请一同参阅图18、图19和图20，图19为图18中检测卡93沿线L-L的剖面图，图20为图18中检测卡93的立体结构示意图。本体94采用硬性材料例如塑料等制成。
本体94整体可为板状结构。大体呈扇形，具体可为扇环形、扇叶形或饼形。例如本体94由两条直线边和一条弧形边首尾依次连接形成的扇形。例如本体94由一条直线边和一条外侧圆弧形边、一条直线边、一条内侧圆弧形边首尾依次连接形成的扇环形。当然本体94也可以为其他形状，不作赘述。
在一实施例中，本体94的扇形结构的两条直线边夹角可为40°-60°，内侧圆弧边直径可以为10mm-100mm，外侧圆弧边直径可以为100mm-200mm。采用这种尺寸结构的检测卡93，在分子诊断设备100的检测平面内可以排布至少6个，组成一个圆形面，从而使得至少6个检测卡93可同时检测，提高了整体的检测效率，能应对较大规模的检测需求。
本体94靠近外侧圆弧边的圆心或内侧圆弧边且向远离隔离层95的一侧凸伸设置安装部941。本体94在靠近隔离层95的一侧且在与安装部941相对的位置凹陷设置加样腔9411，以用于在加样腔9411处进行样本添加。加样腔9411主要用于样本(液体样本)的预处理，其预处理方式可能包括一个或者多个，如化学处理、热处理、酶处理和物理分离等。在一些实施例中，加样腔9411的容积大体为200-2000μl。在加样腔9411内可以预装干燥的试剂，可以在原位风干/烘干，也可以作为冻干试剂添加到加样腔9411中。
本体94在远离隔离层95的一侧且在靠近外侧圆弧边的部位设置第二卡固部942，以与托运组件60例如第一卡固部654配合。在一实施例中，第二卡固部942可为凸起。可以理解地，第一卡固部654可以与第二卡固部942进行位置互换，另外第一卡固部654和第二卡固部942也可以采用其他方式进行卡固配合。
本体94在一条直线边靠近外侧圆弧边的边缘部位向远离隔离层95的一侧弯折设置第一限位部943，在另一条直线边靠近外侧圆弧边的部位向远离隔离层95的一侧凸伸设置第二限位部944。本体94的第一限位部943与第二限位部944配合以对检测卡93进行固定，以便顺利进行检测卡93的离心处理，本体94在靠近隔离层95的一侧且在与第二限位部944相对的位置凹陷设置废液腔9441。本体94在远离隔离层95的一侧且在第一限位部943和第二限位部944之间沿外侧圆弧边的延伸方向均布多个插接部组。每一个插接部组可包括第一插接部945和第二插接部946。第一插接部945和第二插接部946之间的连线可过外侧圆弧边的圆心。第一插接部945置于安装部941与第二插接部946之间。第一插接部945和第二插接部946的设置可与检测卡检测座30例如隔离槽8213、检测槽8212配合。
本体94在靠近隔离层95的一侧且在与第一插接部945相对的位置凹陷设置隔离腔9451。隔离腔9451设置有可熔化的隔离体。隔离体可在熔化状态和未熔化状态(通常为固态)之间切换。在未用检测卡93进行检测时，可以控制隔离体处于未熔化状态，此时，该隔离体可以防止样本通过流道进入检测腔9461(如图20所示)内。在一些实施例中，隔离体可为石蜡、微晶蜡、合成蜡或者天然蜡。
本体94在靠近隔离层95的一侧且在与第二插接部946相对的位置凹陷设置检测腔9461。检测腔9461内设有试剂。隔离腔9451与检测腔9461在靠近隔离层95的一侧连通。隔离腔9451内的隔离体还可用于密封隔离试剂，以防止试剂反向进入隔离腔9451。将试剂维持在检测腔9461内。而在执行测试时，可以控制隔离体处于熔化状态，此时样本可通过加样腔9411进入检测腔9461，以与检测腔9461内的试剂发生反应从而完成检测。
检测腔9461内可层叠式设置有试剂和可熔化的隔离体。在一些实施例中，隔离体可为石蜡、微晶蜡、合成蜡或者天然蜡。隔离体的特点为在常温及低温状态下为固态，在加热至特定温度后变为液态，且对核酸扩增反应无抑制作用。一些实施例中，试剂可为干式试剂，干式试剂包括扩增反应所用的引物和DNA(deoxyribonucleic acid，脱氧核糖核酸)结合染料、酶、硫酸镁、氯化钾、dNTPs(Nucleoside triphosphate，去氧核苷三磷酸)中的一种或多种。干式试剂以液态装入检测腔9461，并通过干燥工艺形成干式试剂，干燥工艺的温度小于隔离体的熔化温度，干燥工艺包括风干、烘干、冻干。在检测加热过程中，试剂和隔离体均呈液态，由于隔离体的比重比试剂小，在离心场作用下，隔离体会被置换出检测腔9461，从而不影响反应和检测。
在一些实施例中，隔离体以熔融状态装入检测腔9461内并通过自然凝固或降温凝固成型。在未测试 时，可以控制隔离体处于未熔化状态，此时可通过隔离体实现试剂的密封隔离存放。而在需要执行测试时，可以控制隔离体处于熔化状态，例如通过对检测卡93进行加热，以使隔离体受热熔化，此时，隔离体在离心力的作用下，可移出检测腔9461并流向隔离腔9451，且样本可进入检测腔9461内，而后隔离体再次固化，以封堵检测腔9461的口部，进而对多个检测腔9461形成相互隔离密封，以便于检测腔9461之间独自进行反应或测试。
本体94在靠近隔离层95的一侧设置有流道947，以连通加样腔9411与隔离腔9451。
本体94在远离隔离层95的一侧且与流道947相对的位置设置有抵接槽948，以便与抵接部8324配合。例如可将抵接部8324置于抵接槽948内，以对流道947的部位进行加热，避免水汽在流道947内冷凝，进而减少对后续检测过程中的影响，提高检测精度。在一些实施例中，抵接槽948可以省略。
隔离层95可为膜状结构，当然也可以为其他结构。隔离层95可采用压密胶、紫外光固化胶或光学级双面胶等材质，也可以是和本体94类似的材质。隔离层95可贴附在本体94上，具体可通过例如超声焊接、激光焊接、胶黏密封等方式进行密封固定，以对流道947、废液腔9441、隔离腔9451和检测腔9461进行隔离。隔离层95可与本体94为一体结构。
盖体96盖设在加样腔9411的口部。以对加样腔9411进行密封隔离。在需要添加样本时，就可将盖体96打开，添加样本至加样腔9411，然后就可以盖合盖体96。盖体96可阻水透气，即可排出加热过程中产生的水蒸气，降低分子诊断离心测试卡内的气压，从而能够保证良好的透气效果，而且可阻隔扩增反应中产生的气溶胶和生物分子等污染物的逸出，避免检测对人员和环境的污染。
检测卡93离心旋转时，样本液体经加样腔9411和流道947。此时隔离体为固态，由此可将检测腔9461密封，样本液体不能流向检测腔9461。在样本液体加热后，隔离体受热熔化流向检测腔9461，使得流道947与检测腔9461之间可连通，样本液体可通过流入检测腔9461内。由于隔离体的比重比试剂小，在离心场作用下，隔离体会被置换到试剂之上，不影响反应和检测，同时可以对检测腔9461进行密封。
可以理解地，在填充有样本的检测卡93进行离心处理时，为了保证填充有样本的检测卡93在卡托65上圆周均布，降低离心处理过程中检测卡93分布不均产生的噪音，可将未填充样本的检测卡93作为配平卡，与填充有样本的检测卡93一同在卡托65上圆周均布，以进行离心处理。
在一些实施例中，在检测卡93作为配平卡使用时，隔离腔9451可不设置隔离体。
在一些实施例中，在检测卡93作为配平卡使用时，检测腔9461中可不设置试剂和隔离体。
在一些实施例中，在检测卡93作为配平卡使用时，本体94与盖体96可为一体结构。
在一些实施例中，在检测卡93作为配平卡使用时，加样腔9411可不设置试剂。
在一些实施例中，在检测卡93作为配平卡使用时，流道947、隔离腔9451、废液腔9441、盖体96中的至少一个结构可以省略。
在一些实施例中，在检测卡93作为配平卡使用时，加样腔9411可以省略，在设置加样腔9411的位置设置与本体94为一体的第三卡固部。具体地，第三卡固部为凸块，以安装在加样腔安装座832。
配平卡不仅可以在离心处理时起到配平、降噪音的作用，还可在检测腔9461的底部设置参比膜以替代试剂和隔离体，进而起到对分子诊断设备的检测组件90进行校正的作用，提高分子诊断设备中检测组件90的检测精度。
在一些实施例中，参比膜的成分可包括荧光指示剂。在某些实施例中，参比膜的成分还可包括辅助试剂，辅助试剂可帮助荧光指示剂形成膜状物。荧光指示剂是指能够受激光照射产生荧光的一类物质。荧光指示剂可在光发生器91的激发光激发下产生荧光，光接收器92可接收荧光指示剂产生的荧光。以在配平卡置于不同的检测腔组件82及不同的加样腔组件83时，对检测卡检测座30中的检测组件90进行检测，以确保检测组件90的正常、准确，可见，配平卡具有对分子诊断设备中的检测组件90进行校正的作用，可提高分子诊断设备的检测精度。
在一些实施例中，参比膜可被液态的荧光指示剂及其他类型的辅助试剂替代，以填充在检测腔9461中。可以理解地，荧光指示剂的形态可不做限定，只要可在光发生器91的激发光激发下产生荧光即可。
本申请的一些实施例中还提供一种基于上述的检测卡93进行检测的方法。该方法可用于上述实施例中分子诊断设备100中。请参阅图21，其为图20中检测卡使用过程示意图。具体步骤可如下：
步骤S2101：加样腔接收样本。
在加样腔9411添加样本后，需要对样本进行加热预处理，加热方式可为金属加热块、加热气流、电磁波(红外辐射、激光、微波)等方式。检测卡的加热区域可为加样腔附近区域。加热过程需升温至指定温度，如90℃。到达指定温度后，按照指定需求保温3-10min实现预处理。待预处理完成后，将样本液体的温度降至指定温度，如60℃。
步骤S2102：检测卡受离心力旋转以使得样本经流道流向检测腔。
对检测卡旋转控制进行离心处理。例如可控制旋转方向为顺时针方向，旋转速度大于1000rpm，旋转 时间约为10-15s。通过旋转，样本液体可由加样腔经流道流向检测腔，以便于后续实现检测腔内样本的填充。而多余的样本液体则将进入废液腔。
步骤S2103：加热熔化隔离体，以使得样本流进检测腔中并与检测腔中的试剂混合。
在此需要针对检测腔附近的区域进行加热处理，使得温度高于隔离体的熔点，进而使隔离体熔化，从而使样本与检测腔中的试剂混合。
步骤S2104：离心旋转，以使得隔离体与检测腔中的样本置换，并密封检测腔的入口端。
再次对检测卡进行旋转控制。其中，电机可以沿顺时针方向旋转，旋转速度大于1000rpm，旋转时间为10-15s。此时，由于检测卡的旋转，使得样本进入检测腔内，且隔离体和检测腔内的水溶液发生置换，隔离体转移至检测腔的入口端，从而完成各个检测腔的密封。然后改变电机控制参数，使检测卡进行顺时针和逆时针交替旋转。例如，可以控制检测卡先顺时针旋转，旋转速度为3000rpm，旋转时间1s，然后逆时针旋转，旋转速度3000rpm，旋转时间1s，交替旋转10-15次。通过这种顺时针、逆时针交替旋转的方式可使检测腔内的样本与试剂混合完全溶解混合。
同时，隔离体加热熔化后在离心力的作用下流至检测腔的入口端，以对检测腔的入口端进行密封。
步骤S2105：对混合后的混合体进行检测。
在此步骤中，需要进行扩增反应和检测。若使用实时检测，则检测和扩增反应同步进行，若使用终点检测，则扩增完成后进行检测。其中，扩增反应可通过以下方式实现：对检测腔附近进行加热，温度控制在60℃-75℃范围。在到达指定温度后，按照指定需求，保温30-60min来完成扩增反应。
接下来阐述利用分子诊断设备100和检测卡93进行样本测试的运行过程，具体运行过程如下：
控制电路板40通过输入设备进行检测卡93的检测样本数量、类型、加热温度、旋转转数、运行参数等基本信息设置。在基本信息设置完毕后，可进一步通过输入设备开启检测卡93的检测。
加载有样本的检测卡93。
在控制电路板40的控制下，第一驱动组件12控制丝杠13转动，使得抵压盘50带动托运组件60在第一导轨111上向远离检测卡检测座30的一侧滑动。抵压盘50到达预定位置。第一驱动组件12停止运行。
在控制电路板40的控制下，第二驱动组件6141通过丝杠6142使得托运件62沿第二导轨613向靠近扫码设备14的一侧滑动。托运件62到达预定位置。第二驱动组件6141停止运行。
将加载有样本的检测卡93放置在托运件62例如卡托65的凹陷部653处。检测卡93例如安装部941置于容置孔655内。检测卡93例如第二卡固部942与卡托65的第一卡固部654卡固，完成一个检测卡93的放置。
控制电路板40通过扫码设备14对卡托65上检测卡93的信息标识进行图像扫描，并判断出是否为用户预定的检测卡93，若否，将进行预警提示。若是就进行下一步骤。
在控制电路板40的控制下，第三驱动组件64开始转动，带动卡托65进行转动，使得下一个可放置检测卡93的凹陷部653到达预定位置，然后操作下一个检测卡93的放置。
在卡托65上的凹陷部653放置检测卡93后，检测卡93会圆周均布在卡托65上。若检测卡93的数量不足以圆周均布在卡托65上，可在卡托65的凹陷部653处放置配平卡，以使得配平卡与检测卡93一同圆周均布在卡托65上。至此检测卡93放置完毕。
在控制电路板40的控制下，第二驱动组件6141通过丝杠6142使得托运件62沿第二导轨613向远离扫码设备14的一侧滑动。托运件62到达预定位置。第二驱动组件6141停止运行。
在控制电路板40的控制下，第一驱动组件12控制丝杠13转动，使得抵压盘50带动托运组件60在第一导轨111上向靠近检测卡检测座30的一侧滑动。在托运件62例如卡托65快碰触到支撑座80例如支撑座主体81时。卡托65朝向支撑座主体81一侧的第一定位件656将伸入第二定位件813，由于第一定位件656的特殊结构，将使得第一定位件656轻松地置于第二定位件813内，实现了对检测卡93的定位。
在卡托65抵接支撑座80例如支撑座主体81时。检测卡93将位于支撑座80上。检测卡93例如安装部941将置于加样腔安装座832的加样腔安置槽8322中。检测卡93例如第一插接部945将置于光检测件821例如隔离槽8213中。检测卡93例如第二插接部946将置于光检测件821例如检测槽8212中。检测卡93例如第一限位部943将置于支撑座主体81例如延伸槽814中，并与装配台815抵接。检测卡93例如第二限位部944将置于支撑座主体81例如延伸槽814中，并与装配台815抵接。至此，完成了检测卡93在支撑座80上的放置。
抵压盘50到达预定位置。第一驱动组件12停止运行。此时，抵压盘50例如第一加热件54抵接检测卡93设置隔离腔9451、检测腔9461的部位，压紧件53对盖体96进行卡固，松开对压紧件53的固定。
在控制电路板40的控制下，加样腔组件83例如加样腔安装座832内的发热器件及第二加热件55内的发热器件进行加热，以完成对检测卡93例如加样腔9411的加热。实现了对样本的加热预处理。
在有电磁件52存在的情况下，需要在控制电路板40的控制下，取消电磁作用力，使得压紧件53置于卡托65上方，并与卡托65卡固，另外，再配合卡托65内部电磁铁、永磁铁等产生的作用力，使得卡托65与压紧件53抵接更紧密。
在控制电路板40的控制下，第一驱动组件12控制丝杠13转动，使得抵压盘50带动托运组件60在第一导轨111上向远离检测卡检测座30的一侧滑动。抵压盘50到达预定位置。第一驱动组件12停止运行。
在控制电路板40的控制下，第三驱动组件64开始转动，带动卡托65进行转动，实现对检测卡的离心处理。
在控制电路板40的控制下，再次将检测卡93输送至支撑座80例如支撑座主体81上。
在控制电路板40的控制下，对第一加热件54内的发热器件进行控制加热，对光检测件821内的发热器件进行控制加热。实现了对检测卡93的二次加热。
然后再次对检测卡93进行离心处理。
最后将检测卡93输送至支撑座80例如支撑座主体81上。
在控制电路板40的控制下，光发生器91发出激发光，在检测槽8212中对检测卡93的检测腔9461中的混合体进行激发。光接收器92接收到荧光。由控制电路板40接收检测信号并进行处理形成诊断数据。
接下来阐述一种基于多通量离心平台的控制方法。该方法可应用于上述分子诊断设备100中，可对上述检测卡93进行检测。该多通量离心平台可为上述分子诊断设备100。该方法可包括检测卡放置流程和检测卡测量流程，可在检测卡放置流程中实现检测卡在多通量离心平台例如分子诊断设备100上的放置。请参阅图22，图22为本申请中一实施例中基于多通量离心平台的控制方法流程图。该方法可包括：
步骤S2201：获取检测卡数量。
多通量离心平台例如分子诊断设备100对检测卡93进行检测时，需要对检测卡93进行离心处理。而多通量离心平台例如分子诊断设备100会设置放置检测卡93的卡托65。每一个卡托65上可设置多个卡位(即图9中的凹陷部653)。例如图9中的卡托65上可设置6个卡位。可以理解地多通量离心平台不同，卡托上的卡位数量不同。
多通量离心平台例如分子诊断设备100在对检测卡93进行离心处理时，会将检测卡对称式的放置在卡托65上的卡位上，以达到检测卡93放置在卡位上，使得卡托65上重量分布均衡。若检测卡93放置在卡位上，使得卡托65上重量分布不均衡，会产生偏心力，进而使得多通量离心平台例如分子诊断设备100在离心过程中产生大量的噪音。
在常规测量过程中，多通量离心平台例如分子诊断设备100总是以最大量的检测卡数量填满卡托65，进而不会存在卡托65上重量分布不均衡的问题。但是也会出现特殊情况，在使用多通量离心平台例如分子诊断设备100的过程中，出现检测卡数量不足以填满卡托65，存在卡托65上重量分布不均衡的问题情况。此情况尤其是在人工放置检测卡93时更容易出现。
而对于多通量离心平台例如分子诊断设备100，可在卡托93向扫码设备14一侧滑动时，仅会在落卡口处显露出一个卡位。然后进行转动，再在落卡口处显露其他卡位。若是人工在卡托65上放置检测卡93，则进一步增加了放置检测卡93的难度，极难使得卡托65上重量分布均衡。而本方法可以辅助人工放置检测卡93，进而使得人工放置检测卡的出错率降低，也解决了多通量离心平台例如分子诊断设备100在离心过程中产生大量噪音的问题。
在一些实施例中，在卡托65上放置检测卡93配平时，检测卡数量作为基础数据而显得尤为重要。在一些实施例中，检测卡数量可以由用户根据实际情况通过显示器、键盘、扫码设备14等输入设备输入多通量离心平台例如分子诊断设备100的系统中，以使得多通量离心平台例如分子诊断设备100的系统根据检测卡数量辅助用户完成检测卡93在卡托65上的配平过程。
在一些实施例中，请参阅图9，卡托65上的卡位为6个，在检测卡数量为1个或5个时，无法进行在卡托65上进行重量分布均衡。因此，可在检测卡数量不足以在卡托65上配平时，引入上述实施例中记载的配平卡，使得卡例如检测卡、配平卡的数量和足以在卡托65上进行重量分布均衡。例如检测卡数量为1个，辅以配平卡1个，则卡数量和为2个，足以在卡托65上进行重量分布均衡。例如检测卡数量为5个，辅以配平卡1个，则卡数量和为6个，足以在卡托65上进行重量分布均衡。
步骤S2202：确定对应检测卡数量的多通量离心平台的卡托旋转策略。
对于多通量离心平台例如分子诊断设备100，可在卡托93向扫码设备14一侧滑动时，仅会在落卡口处显露出一个卡位。然后进行转动，再在落卡口处显露其他卡位。因此，检测卡93可以在卡托65上进行重量分布均衡，或检测卡与配平卡可以在卡托65上进行重量分布均衡时，可以通过在落卡口处显露一个卡位，来引导用户进行检测卡放置。进而完成多通量离心平台例如分子诊断设备100辅助用户在卡托 65上放置检测卡93的过程。因此本方法可以辅助人工放置检测卡93，进而使得人工放置检测卡的出错率降低，也解决了多通量离心平台例如分子诊断设备100在离心过程中产生大量噪音的问题。
在一些实施例中，在检测卡数量确定时，多通量离心平台例如分子诊断设备100就可根据检测卡数量确定所需卡位的数量及位置，进而由所需卡位的数量及位置进一步确定卡托65如何在落卡口处转动的卡托旋转策略，以使得卡托按照策略转动，以通过在落卡口处显露卡位的方式提示用户放置检测卡或配平卡进行配平。
在一些实施例中，利用预设算法对检测卡数量及卡托上的卡位数量进行配平计算，以得到策略。在一实施例中，预设算法可设置在多通量离心平台例如分子诊断设备100的系统中。在一些实施例中，也可以将策略与检测卡数量进行关系预对应并预设在多通量离心平台例如分子诊断设备100的系统中，以在获取到检测卡数量时，进行关系预对应查找，进而获得策略。在一实施例中，策略中可包括卡托转动使得所需卡位的位置依次显露，以使得卡例如检测卡、配平卡放置在落卡口处显露的卡位上。当然，策略还可包括卡托转动的方向例如顺时针或逆时针转动。甚至，策略还可包括卡位在落卡口处显露时，并通过指示灯、语音等方式提醒用户在卡位上进行检测卡或配平卡的放置。例如，在落卡口处放置检测卡，则通过语音播报提醒用户放置检测卡。例如，在落卡口处放置配平卡，则通过指示灯闪烁提醒用户放置配平卡。
步骤S2202：控制卡托按照策略旋转，在落卡口处显露卡托的卡位。
在策略形成后，即可按照策略控制卡托转动，使得所需卡位的位置依次在落卡口处显露。用户仅需在落卡口处显露卡位时放置检测卡或配平卡即可完成配平，保障了多通量离心平台例如分子诊断设备100的安全运行。
在一些实施例中，请参阅图23，图23为本申请中另一实施例中基于多通量离心平台的控制方法流程图。在步骤S2202之前，该方法还包括：
步骤S2301：确定前次控制多通量离心平台工作的工作模式指令。
多通量离心平台例如分子诊断设备100的工作模式指令可包括需要配平卡进行配平的模式指令，以及不需要配平卡进行配平的模式指令。其中，两种工作模式指令各有特点。例如，需要配平卡进行配平的模式指令，会在对检测卡进行配平时生成需要配平卡参与的策略，而且在检测卡检测完成时，不会将配平卡取出。例如，不需要配平卡进行配平的模式指令，会在对检测卡进行配平时优先根据检测卡生成策略，在检测卡无法完成配平时生成需要配平卡参与的策略，若有配平卡参与时，需在检测卡检测完成时，将配平卡取出。
两种工作模式指令的设置可以使得用户根据需求进行选择，以更好的提升检测效率。在一些实施例中，多通量离心平台例如分子诊断设备100的工作模式指令可通过显示器、键盘、扫码设备14等输入设备输入，以控制多通量离心平台例如分子诊断设备100。可以理解地，多通量离心平台例如分子诊断设备100的工作模式指令也可包括其他工作模式指令，在此不做赘述。
所以前次控制多通量离心平台工作的工作模式指令会使得用户考虑卡托在当前检测卡检测时是否存在配平卡，当前检测卡配平是否需要配平卡参与，及配平卡是否取放等操作。
而步骤S2202可包括：
步骤S2302：结合检测卡数量、前次控制多通量离心平台工作的工作模式指令，得到策略。
由于前次控制多通量离心平台工作的工作模式指令会使得卡托上留有配平卡，所以需要在策略生成时，会基于前次控制多通量离心平台工作的工作模式指令考虑卡托上是否存在配平卡的问题。在一些实施例中，若前次控制多通量离心平台工作的工作模式指令为需要配平卡进行配平的模式指令时，则当前卡托上存在配平卡。在一些实施例中，若前次控制多通量离心平台工作的工作模式指令为不需要配平卡进行配平的模式指令时，则当前卡托上不存在配平卡。在一些实施例中，在当前卡托存在配平卡时，可先取出配平卡，然后再执行当前控制多通量离心平台工作的工作模式指令，即按照检测卡数量生成策略。在一些实施例中，在当前卡托存在配平卡时，可直接生成需要配平卡参与的策略，以减少配平卡取出的步骤，提高检测效率。在一些实施例中，在当前卡托存在配平卡，且无法直接生成需要配平卡参与的策略，则可以取出配平卡，生成不需要配平卡参与的策略。以提高多通量离心平台例如分子诊断设备100的智能度。
可以理解地，步骤S2301可与步骤S2201同时进行，也可以先进行步骤S2301，再进行步骤S2201，也可以先进行步骤S2201，再进行步骤S2301。
在一些实施例中，请参阅图24，图24为本申请中另一实施例中基于多通量离心平台的控制方法流程图。步骤S2301可包括：确定前次控制多通量离心平台工作的工作模式指令为需要配平卡进行配平的模式指令。
步骤S2302可包括：
步骤S2401：获得检测卡数量和卡托内配平卡数量的数量和。
在前次控制多通量离心平台工作的工作模式指令为需要配平卡进行配平的模式指令，则当前卡托上是放置有配平卡的。因此在执行当前控制多通量离心平台工作的工作模式指令之前，取出配平卡，则会因为当前控制多通量离心平台工作的工作模式指令需要配平卡而再次放入配平卡，进而导致操作步骤繁琐，而降低检测效率。为了提升检测效率，则可以在不取出配平卡即可完成检测时则不取出。
因此，需要判断是否可以生成需要配平卡参与的策略，进而可以通过检测卡数量和卡托内配平卡数量的数量和来确定。
步骤S2402：根据数量和以及卡托的卡位数量，得到策略。
在存在配平卡时，可以根据数量和获取到相应的策略。这个策略可以是需要配平卡参与的策略，也可以是不需要配平卡参与的策略。在一些实施例中，若响应于根据数量和以及卡托的卡位数量无法配平的结果，则可以直接以检测卡数量进行配平以得到策略。在一些实施例中，响应于根据数量和以及卡托的卡位数量无法配平的结果，在落卡口处显露放置配平卡的卡位，以便用户将配平卡取出，并执行策略以进行检测卡在卡托上的放置。在一些实施例中，响应于根据数量和以及卡托的卡位数量无法配平的结果，将当前控制多通量离心平台工作的工作模式指令记录为不需要配平卡进行配平的模式指令。由于无法配平则必须取出配平卡。若当前控制多通量离心平台工作的工作模式指令为需要配平卡进行配平的模式指令，则检测完成后配平卡没有配平卡，则会引发系统错误，进而导致下一次的检测卡配平是无法配平。因此，可以将当前控制多通量离心平台工作的工作模式指令更改为不需要配平卡进行配平的模式指令，以便下一次检测卡配平的顺利进行。当然，也可以在检测完成时，在落卡口处显露一卡位，以使用户放置配平卡，以使得当前控制多通量离心平台工作的工作模式指令依旧为需要配平卡进行配平的模式指令，并能顺利进行下一次的检测卡配平。
在一些实施例中，步骤S2402可包括响应于根据数量和以及卡托的卡位数量能配平的结果，以数量和以及卡托的卡位数量进行配平以得到策略。
步骤S2203可包括：响应于对应配平卡的卡位初始位置不在落卡口，控制卡托按照策略旋转以将对应配平卡的卡位跳过落卡口，在落卡口处显露卡托的空卡位。
而对于多通量离心平台例如分子诊断设备100，可在卡托93向扫码设备14一侧滑动时，仅会在落卡口处显露出一个卡位。在一些实施例中，此卡位可为放置有配平卡的卡位，则可以按照策略转动，显露其他所需卡位，以在卡托上放置检测卡。在一些实施例中，此卡位为空卡位，则说明配平卡放置在其他位置，可按照策略转动，因为有一个所需卡位放置有配平卡，而配平卡又无需取出，所以，即可在落卡口处跳过对应配平卡的卡位，以显露其他所需卡位，进而可提升检测效率，也避免用户取出检测卡的错误操作。
在一些实施例中，步骤S2301可包括：确定前次控制多通量离心平台工作的工作模式指令为不需要配平卡进行配平的模式指令。
步骤S2302可包括：结合检测卡数量以及卡托的卡位数量，得到策略。
可以理解地，在前次控制多通量离心平台工作的工作模式指令为不需要配平卡进行配平的模式指令，则当前卡托上是不存在配平卡的。进而在执行当前控制多通量离心平台工作的工作模式指令时，可仅依据检测卡数量及卡托的卡位数量进行配平，以得到策略。当然，所得的策略可以为不需要配平卡参与的策略，也可以为需要配平卡参与的策略。即，响应于根据检测卡数量以及卡托的卡位数量无法配平的结果，以配平卡进行配平，得到策略。
在一些实施例中，请参阅图25，图25为本申请中另一实施例中基于多通量离心平台的控制方法流程图。在步骤S2203之前，该方法还可包括：
步骤S2501：确定当前控制多通量离心平台工作的工作模式指令为需要配平卡进行配平的模式指令。
在步骤S2203之后，该方法还包括：
步骤S2502：将卡托内的对应配平卡的卡位旋转至指定位置，以进行复位。
在当前控制多通量离心平台工作的工作模式指令为需要配平卡进行配平的模式指令，则在检测卡检测完成后，需保留配平卡在卡托上。因此需要对配平卡进行复位，以使得下一次检测卡配平操作顺利进行，并可提升检测效率。而指定位置可以为卡托93向扫码设备14一侧滑动时，会在落卡口处显露出一个卡位。当然，考虑到配平效果，指定位置也可以为与卡托93向扫码设备14一侧滑动以在落卡口处显露出卡位相对的一个卡位。当然，也可以为其他卡位，例如，将卡托内的没有配平卡的卡位旋转至与落卡口对应的位置。
可以理解地，步骤S2501可与步骤S2301为同一步骤，也可以不是同一步骤。
在一些实施例中，在落卡口处显露卡位时，可以按照策略通过指示灯、语音等方式提醒用户在卡位上进行检测卡或配平卡的放置，也可以提醒用户取出检测卡或配平卡。当然，在一些实施例中，在落卡 口处放置卡例如检测卡、配平卡时，扫码设备可以开启以获取信息，并判断仿制的卡类型是否正确，并可在不正确时按照策略通过指示灯、语音等方式提醒用户在卡位上进行检测卡或配平卡的放置，或提醒放卡错误。
接下来阐述一种多通量离心平台97，该多通量离心平台97可应用于上述方法中，也可应用于上述基于多通量离心平台例如分子诊断设备100中。请参图26，图26为本申请一实施例中多通量离心平台的结构示意图。该多通量离心平台97包括：
获取模块971，用于获取检测卡数量；
确定模块972，用于确定对应检测卡数量的多通量离心平台的卡托旋转策略；以及
控制模块973，用于控制卡托按照策略旋转，在落卡口处显露卡托的卡位。
在一些实施例中，确定模块972用于利用预设算法对检测卡数量及卡托上的卡位数量进行配平计算，以得到策略。
在一些实施例中，在确定模块972确定对应检测卡数量的多通量离心平台的卡托旋转策略之前，确定模块972用于确定前次控制多通量离心平台工作的工作模式指令，工作模式指令是需要配平卡进行配平的模式指令，或不需要配平卡进行配平的模式指令。进一步地，确定模块972用于结合检测卡数量、前次控制多通量离心平台工作的工作模式指令，得到策略。
在一些实施例中，确定模块972用于确定前次控制多通量离心平台工作的工作模式指令为需要配平卡进行配平的模式指令。进一步地，确定模块972用于获得检测卡数量和卡托内配平卡数量的数量和，并根据数量和以及卡托的卡位数量，得到策略。在一些实施例中，确定模块972用于响应于根据数量和以及卡托的卡位数量无法配平的结果，直接以检测卡数量进行配平以得到策略。在一些实施例中，控制模块973用于响应于根据数量和以及卡托的卡位数量无法配平的结果，在落卡口处显露放置配平卡的卡位。在一些实施例中，控制模块973用于响应于根据数量和以及卡托的卡位数量无法配平的结果，将当前控制多通量离心平台工作的工作模式指令记录为不需要配平卡进行配平的模式指令。
在一些实施例中，确定模块972用于响应于根据数量和以及卡托的卡位数量能配平的结果，以数量和以及卡托的卡位数量进行配平以得到策略。进一步地，控制模块973用于响应于对应配平卡的卡位初始位置不在落卡口，控制卡托按照策略旋转以将对应配平卡的卡位跳过落卡口，在落卡口处显露卡托的空卡位。
在一些实施例中，确定模块972用于确定前次控制多通量离心平台工作的工作模式指令为不需要配平卡进行配平的模式指令。进一步地，确定模块972用于结合检测卡数量以及卡托的卡位数量，得到策略。在一些实施例中，确定模块972用于响应于根据检测卡数量以及卡托的卡位数量无法配平的结果，以配平卡进行配平，得到策略。
在一些实施例中，在控制模块973控制卡托按照策略旋转，在落卡口处显露卡托的卡位之前，确定模块972用于确定当前控制多通量离心平台工作的工作模式指令为需要配平卡进行配平的模式指令。进一步地，在控制模块973控制卡托按照策略旋转，在落卡口处显露卡托的卡位之后，控制模块973用于将卡托内的对应配平卡的卡位旋转至指定位置，以进行复位。在一些实施例中，控制模块973用于将卡托内的没有配平卡的卡位旋转至落卡口，以完成复位。
接下来阐述一种计算机可读存储介质，请参阅图27，图27为本申请中一实施例的一种计算机可读存储介质的框架示意图。此计算机可读存储介质98存储有计算机程序981，此计算机程序981被处理器执行时实现上述检测卡放置流程中基于多通量离心平台的自动配平方法。
该计算机可读存储介质98具体可以为U盘、移动硬盘、只读存储器(ROM，Read-Only Memory)、随机存取存储器(RAM，Random Access Memory)、磁碟或者光盘等可以存储程序指令的介质，或者也可以为存储有该程序指令的服务器，该服务器可将存储的程序指令发送给其他设备运行，或者也可以自运行该存储的程序指令。
在本申请所提供的几个实施方式中，应该理解到，所揭露的方法以及设备，可以通过其他的方式实现。例如，以上所描述的设备实施方式仅仅是示意性的，例如，模块或单元的划分，仅仅为一种逻辑功能划分，实际实现时可以有另外的划分方式，例如多个单元或组件可以结合或者可以集成到另一个系统，或一些特征可以忽略，或不执行。
作为分离部件说明的单元可以是或者也可以不是物理上分开的，作为单元显示的部件可以是或者也可以不是物理单元，即可以位于一个地方，或者也可以分布到多个网络单元上。可以根据实际的需要选择其中的部分或者全部单元来实现本实施方式方案的目的。
另外，在本申请各个实施方式中的各功能单元可以集成在一个处理单元中，也可以是各个单元单独物理存在，也可以两个或两个以上单元集成在一个单元中。上述集成的单元既可以采用硬件的形式实现，也可以采用软件功能单元的形式实现。
以上所述仅为本申请的实施例，并非因此限制本申请的专利范围，凡是利用本申请说明书及附图内容所作的等效结构或等效流程变换，或直接或间接运用在其他相关的技术领域，均同理包括在本申请的专利保护范围内。

Claims (20)

  1. 一种基于多通量离心平台的控制方法，其中，包括：
    获取检测卡数量；
    确定对应所述检测卡数量的所述多通量离心平台的卡托旋转策略；
    控制所述卡托按照所述策略旋转，在落卡口处显露所述卡托的卡位。
  2. 根据权利要求1所述的方法，其中，所述确定对应所述检测卡数量的所述多通量离心平台的卡托旋转策略包括：
    利用预设算法对所述检测卡数量及所述卡托上的卡位数量进行配平计算，以得到所述策略。
  3. 根据权利要求1所述的方法，其中，在所述确定对应所述检测卡数量的所述多通量离心平台的卡托旋转策略之前，所述方法还包括：
    确定前次控制所述多通量离心平台工作的工作模式指令，所述工作模式指令是需要配平卡进行配平的模式指令，或不需要所述配平卡进行配平的模式指令；
    所述确定对应所述检测卡数量的所述多通量离心平台的卡托旋转策略包括：
    结合所述检测卡数量、所述前次控制所述多通量离心平台工作的工作模式指令，得到所述策略。
  4. 根据权利要求3所述的方法，其中，所述确定前次控制所述多通量离心平台工作的工作模式指令包括：
    确定所述前次控制所述多通量离心平台工作的工作模式指令为需要配平卡进行配平的模式指令；
    所述结合所述检测卡数量、所述前次控制所述多通量离心平台工作的工作模式指令，得到所述策略包括：
    获得所述检测卡数量和所述卡托内所述配平卡数量的数量和；
    根据所述数量和以及所述卡托的卡位数量，得到所述策略。
  5. 根据权利要求4所述的方法，其中，所述根据所述数量和以及所述卡托的卡位数量，得到所述策略包括：
    响应于根据所述数量和以及所述卡托的卡位数量无法配平的结果，直接以所述检测卡数量进行配平以得到所述策略。
  6. 根据权利要求5所述的方法，其中，所述控制所述卡托按照所述策略旋转，在落卡口处显露所述卡托的卡位包括：
    响应于根据所述数量和以及所述卡托的卡位数量无法配平的结果，在所述落卡口处显露放置所述配平卡的卡位。
  7. 根据权利要求4-6任一项所述的方法，其中，所述方法还包括：
    响应于根据所述数量和以及所述卡托的卡位数量无法配平的结果，将当前控制所述多通量离心平台工作的工作模式指令记录为不需要配平卡进行配平的模式指令。
  8. 根据权利要求4所述的方法，其中，所述根据所述数量和以及所述卡托的卡位数量，得到所述策略包括：
    响应于根据所述数量和以及所述卡托的卡位数量能配平的结果，以所述数量和以及所述卡托的卡位数量进行配平以得到所述策略；
    所述控制所述卡托按照所述策略旋转，在落卡口处显露所述卡托的卡位包括：
    响应于对应所述配平卡的所述卡位初始位置不在所述落卡口，控制所述卡托按照所述策略旋转以将对应所述配平卡的所述卡位跳过所述落卡口，在所述落卡口处显露所述卡托的空卡位。
  9. 根据权利要求3所述的方法，其中，所述确定前次控制所述多通量离心平台工作的工作模式指令包括：
    确定所述前次控制所述多通量离心平台工作的工作模式指令为不需要配平卡进行配平的模式指令；
    所述结合所述检测卡数量、所述前次控制所述多通量离心平台工作的工作模式指令，得到所述策略包括：
    结合所述检测卡数量以及所述卡托的卡位数量，得到所述策略。
  10. 根据权利要求9所述的方法，其中，
    响应于根据所述检测卡数量以及所述卡托的卡位数量无法配平的结果，以所述配平卡进行配平，得到所述策略。
  11. 根据权利要求9所述的方法，其中，在所述控制所述卡托按照所述策略旋转，在落卡口处显露所述卡托的卡位之前，所述方法还包括：
    确定当前控制所述多通量离心平台工作的工作模式指令为需要配平卡进行配平的模式指令；
    在所述控制所述卡托按照所述策略旋转，在落卡口处显露所述卡托的卡位之后，所述方法包括：
    将所述卡托内的对应所述配平卡的所述卡位旋转至指定位置，以进行复位。
  12. 根据权利要求11所述的方法，其中，所述将所述卡托内的对应所述配平卡的所述卡位旋转至指定位置包括：
    将所述卡托内的没有所述配平卡的所述卡位旋转至所述落卡口。
  13. 一种基于多通量离心平台，其中，包括：
    获取模块，用于获取检测卡数量；
    确定模块，用于确定对应所述检测卡数量的所述多通量离心平台的卡托旋转策略；
    控制模块，用于控制所述卡托按照所述策略旋转，在落卡口处显露所述卡托的卡位。
  14. 根据权利要求13所述的基于多通量离心平台，其中，所述确定模块用于利用预设算法对所述检测卡数量及所述卡托上的卡位数量进行配平计算，以得到所述策略。
  15. 根据权利要求13所述的基于多通量离心平台，其中，在所述确定模块确定对应所述检测卡数量的所述多通量离心平台的卡托旋转策略之前，所述确定模块用于确定前次控制所述多通量离心平台工作的工作模式指令，所述工作模式指令是需要配平卡进行配平的模式指令，或不需要所述配平卡进行配平的模式指令；
    所述确定模块用于结合所述检测卡数量、所述前次控制所述多通量离心平台工作的工作模式指令，得到所述策略。
  16. 根据权利要求15所述的基于多通量离心平台，其中，所述确定模块用于确定所述前次控制所述多通量离心平台工作的工作模式指令为需要配平卡进行配平的模式指令；
    所述确定模块用于获得所述检测卡数量和所述卡托内所述配平卡数量的数量和，并根据所述数量和以及所述卡托的卡位数量，得到所述策略。
  17. 根据权利要求16所述的基于多通量离心平台，其中，所述确定模块用于响应于根据所述数量和以及所述卡托的卡位数量无法配平的结果，直接以所述检测卡数量进行配平以得到所述策略。
  18. 根据权利要求17所述的基于多通量离心平台，其中，所述控制模块用于响应于根据所述数量和以及所述卡托的卡位数量无法配平的结果，在所述落卡口处显露放置所述配平卡的卡位。
  19. 根据权利要求16-18任一项所述的基于多通量离心平台，其中，所述控制模块用于响应于根据所述数量和以及所述卡托的卡位数量无法配平的结果，将当前控制所述多通量离心平台工作的工作模式指令记录为不需要配平卡进行配平的模式指令。
  20. 一种计算机可读存储介质，其上存储有计算机程序，其中，所述计算机程序被处理器执行时实现基于多通量离心平台的控制方法，所述方法包括：
    获取检测卡数量；
    确定对应所述检测卡数量的所述多通量离心平台的卡托旋转策略；
    控制所述卡托按照所述策略旋转，在落卡口处显露所述卡托的卡位。
PCT/CN2023/077942 2022-02-25 2023-02-23 控制方法、多通量离心平台及计算机可读存储介质 WO2023160623A1 (zh)

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Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103028498A (zh) * 2012-06-25 2013-04-10 卢瑾 一种离心前自动配平的装置和方法
CN103299196A (zh) * 2010-12-28 2013-09-11 株式会社日立高新技术 离心分离装置、具备离心分离装置的前处理系统以及该系统的控制方法
EP2842632A1 (en) * 2013-08-25 2015-03-04 Molecular Devices, LLC Centrifuge Apparatus, Centrifuge Tube, and Method for Automated Cell Preparation
CN105203539A (zh) * 2015-10-15 2015-12-30 山东麦田生物技术有限公司 转盘式多项目免疫层析定量分析系统
CN109046477A (zh) * 2018-07-23 2018-12-21 深圳市刚竹医疗科技有限公司 离心微流控装置
CN112604822A (zh) * 2020-12-04 2021-04-06 广东乾晖生物科技有限公司 离心管自动配平仪
CN217278418U (zh) * 2022-02-25 2022-08-23 深圳市理邦精密仪器股份有限公司 分子诊断设备及用于分子诊断设备的离心组件
CN115463754A (zh) * 2021-12-15 2022-12-13 深圳市瑞图生物技术有限公司 一种离心系统、样本离心方法和液基一体机

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103299196A (zh) * 2010-12-28 2013-09-11 株式会社日立高新技术 离心分离装置、具备离心分离装置的前处理系统以及该系统的控制方法
CN103028498A (zh) * 2012-06-25 2013-04-10 卢瑾 一种离心前自动配平的装置和方法
EP2842632A1 (en) * 2013-08-25 2015-03-04 Molecular Devices, LLC Centrifuge Apparatus, Centrifuge Tube, and Method for Automated Cell Preparation
CN105203539A (zh) * 2015-10-15 2015-12-30 山东麦田生物技术有限公司 转盘式多项目免疫层析定量分析系统
CN109046477A (zh) * 2018-07-23 2018-12-21 深圳市刚竹医疗科技有限公司 离心微流控装置
CN112604822A (zh) * 2020-12-04 2021-04-06 广东乾晖生物科技有限公司 离心管自动配平仪
CN115463754A (zh) * 2021-12-15 2022-12-13 深圳市瑞图生物技术有限公司 一种离心系统、样本离心方法和液基一体机
CN217278418U (zh) * 2022-02-25 2022-08-23 深圳市理邦精密仪器股份有限公司 分子诊断设备及用于分子诊断设备的离心组件

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