WO2023096535A1 - Moyen pour personnes arrêtant de fumer - Google Patents
Moyen pour personnes arrêtant de fumer Download PDFInfo
- Publication number
- WO2023096535A1 WO2023096535A1 PCT/RU2022/050315 RU2022050315W WO2023096535A1 WO 2023096535 A1 WO2023096535 A1 WO 2023096535A1 RU 2022050315 W RU2022050315 W RU 2022050315W WO 2023096535 A1 WO2023096535 A1 WO 2023096535A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- nicotine
- smoking
- means according
- toothpaste
- surfactant
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/25—Silicon; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/35—Ketones, e.g. benzophenone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Definitions
- the claimed invention relates to means for quitting smoking, and can be used as a means of gradual weaning from a bad habit.
- Nasal drops containing nicotine have been reported (Russell et al., British Medical Journal, Vol. 286, p. 683 (1983); Jarvis et al., Brit. J. on Addiction, Vol. 82, p. 983 (1987)) . Nose drops, however, are difficult to application and inconvenient for use at work or in other social situations.
- the introduction of nicotine by delivery directly into the nasal cavity by spraying is known from US Patent No. 4 579 858, DE 32 41 437 and WO93/12764.
- local nasal irritation may occur with the use of nasal nicotine formulations.
- the complexity of administration also leads to unpredictability of the dose of nicotine administered.
- Nicorette® chewing gum One of the successful products that are used as a smoking substitute and/or as a smoking cessation agent and which are based on nicotine is Nicorette® chewing gum.
- This product was one of the first forms of nicotine replacement approved by the Food and Drug Administration (FDA) and is still one of the most commonly used nicotine replacement products today.
- Nicorette® chewing gum has been on the market for several years in about 60 countries. In this chewing gum, nicotine is present as a complex with an insoluble cation exchanger (polacrylex) which is dispersed in the gum base. Nicotine is slowly released from chewing gum by chewing and reaches the same plasma level as when smoking a cigarette after about 30 minutes, depending on the method of chewing, i.e. slowly or actively.
- Patents related to this product are, for example, US Patent No. 3877,468, US Patent No. 3,901,248 and US Patent No. 3,845,217.
- the present invention mainly aims to provide a tool for quitting smoking, providing an increase in the effectiveness of quitting smoking, which is the achieved technical result.
- the tool for quitting smoking is made in the form of a toothpaste of the following composition, wt. %: abrasives 70-78%, including talc humectants 10-15% fragrances and/or perfume and/or sweeteners 5-10% preservatives and fresheners 5-10%
- this tool for quitting smoking compares favorably with chewing gum containing nicotine, in that when chewing, an unconditioned reflex occurs with the release of gastric juice, but the appetite does not increase, because. nicotine enters the body, this combination inevitably leads to gastritis and stomach ulcers.
- glycerin is used as a humectant. Due to this advantageous characteristic, it becomes possible to use an inexpensive product as a humectant, which is miscible with water in any proportions, and is partly a sweetener.
- camphor is used as a preservative. Thanks to this advantageous characteristic, it becomes possible to use the fact that camphor has anti-inflammatory and antiseptic effects.
- blowing agent In general, cheaper laurils, as well as natural soap grass and other blowing agents, can be used as a blowing agent.
- patchouli essential oil is used as a fragrance. Thanks to this advantageous characteristics, it becomes possible for toothpaste due to patchouli essential oil to have a more pronounced antibacterial effect.
- mint is used as a fragrance. Thanks to this advantageous characteristic, it becomes possible to give the toothpaste a refreshing effect on the mouth.
- agar-agar is used as a sweetener. Thanks to this advantageous characteristic, it becomes possible to increase the therapeutic effect of the use of the proposed toothpaste, since the algae that produce agar-agar are unusually rich in iodine, calcium, iron and other valuable substances and trace elements.
- nicotine When using the claimed means for quitting smoking, nicotine is absorbed through the oral mucosa during brushing your teeth (as when smoking), but without polluting the lungs with combustion products, and also, without getting into digestion with saliva, as when smoking (chewing gum and tablets), it is rinsed with paste. Pure nicotine, received by the body through the mucosa, reduces the need for smoking, thereby facilitating the condition of the smoker during periods of withdrawal and helps restore vital activity, gradually reducing smoking.
- the proposed tool for quitting smoking in the form of a toothpaste containing nicotine has successfully passed certification in the Russian certification center for compliance with the requirements of the standards. In addition, many consumers have already appreciated the effect of using this tool.
- the data are based on the opinions of smokers, recommendations of doctors and instructions for the use of drugs.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Birds (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medical Informatics (AREA)
- Addiction (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Inorganic Chemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Cosmetics (AREA)
Abstract
La présente invention concerne des moyens pour les personnes arrêtant de fumer, et peut être utilisée en qualité de moyen pour se détacher progressivement d'un habitude nocive. Selon l'invention, ce moyen se présente sous forme d'un dentifrice ayant la composition suivante en % en poids: substances abrasives, dont talc, 70-78%; substance de maintien d'humidité 10-15%; arômes et/ou parfum et/ou édulcorants 5-10%; STA 1-5%; nicotine 1-5%. Le résultat technique consiste en une meilleure efficacité pour arrêter de fumer.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2021134721 | 2021-11-26 | ||
RU2021134721A RU2782018C1 (ru) | 2021-11-26 | Средство для бросающих курить |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2023096535A1 true WO2023096535A1 (fr) | 2023-06-01 |
Family
ID=86540242
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/RU2022/050315 WO2023096535A1 (fr) | 2021-11-26 | 2022-10-06 | Moyen pour personnes arrêtant de fumer |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2023096535A1 (fr) |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3877468A (en) * | 1970-07-22 | 1975-04-15 | Leo Ab | Chewable tobacco substitute composition |
US4187288A (en) * | 1975-01-28 | 1980-02-05 | Colgate Palmolive Company | Modified abrasive system for dentifrices |
WO1992010147A1 (fr) * | 1990-12-14 | 1992-06-25 | Mondre Steven J | Fil dentaire contenant de la nicotine |
RU2600443C1 (ru) * | 2015-07-17 | 2016-10-20 | Леонид Борисович Потёмкин | Лечебно-профилактическая зубная паста |
KR101930386B1 (ko) * | 2012-05-24 | 2019-03-11 | 주식회사 엘지생활건강 | 금연 보조용 조성물 및 이를 포함하는 구강 위생 제품 |
EP2435013B1 (fr) * | 2009-05-26 | 2019-07-24 | Colgate-Palmolive Company | Composition de dentifrice |
-
2022
- 2022-10-06 WO PCT/RU2022/050315 patent/WO2023096535A1/fr unknown
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3877468A (en) * | 1970-07-22 | 1975-04-15 | Leo Ab | Chewable tobacco substitute composition |
US4187288A (en) * | 1975-01-28 | 1980-02-05 | Colgate Palmolive Company | Modified abrasive system for dentifrices |
WO1992010147A1 (fr) * | 1990-12-14 | 1992-06-25 | Mondre Steven J | Fil dentaire contenant de la nicotine |
EP2435013B1 (fr) * | 2009-05-26 | 2019-07-24 | Colgate-Palmolive Company | Composition de dentifrice |
KR101930386B1 (ko) * | 2012-05-24 | 2019-03-11 | 주식회사 엘지생활건강 | 금연 보조용 조성물 및 이를 포함하는 구강 위생 제품 |
RU2600443C1 (ru) * | 2015-07-17 | 2016-10-20 | Леонид Борисович Потёмкин | Лечебно-профилактическая зубная паста |
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