WO2023075186A1 - Système d'électrodes bipolaires à usage médical - Google Patents

Système d'électrodes bipolaires à usage médical Download PDF

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Publication number
WO2023075186A1
WO2023075186A1 PCT/KR2022/014815 KR2022014815W WO2023075186A1 WO 2023075186 A1 WO2023075186 A1 WO 2023075186A1 KR 2022014815 W KR2022014815 W KR 2022014815W WO 2023075186 A1 WO2023075186 A1 WO 2023075186A1
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WO
WIPO (PCT)
Prior art keywords
electrode
shaft
coupled
catheter
active
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PCT/KR2022/014815
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English (en)
Korean (ko)
Inventor
김경태
Original Assignee
주식회사 바이오유닛
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Publication of WO2023075186A1 publication Critical patent/WO2023075186A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1482—Probes or electrodes therefor having a long rigid shaft for accessing the inner body transcutaneously in minimal invasive surgery, e.g. laparoscopy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/70—Manipulators specially adapted for use in surgery
    • A61B34/71—Manipulators operated by drive cable mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
    • A61B2017/00292—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery mounted on or guided by flexible, e.g. catheter-like, means
    • A61B2017/003—Steerable
    • A61B2017/00318—Steering mechanisms
    • A61B2017/00323—Cables or rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00234—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery
    • A61B2017/00292—Surgical instruments, devices or methods, e.g. tourniquets for minimally invasive surgery mounted on or guided by flexible, e.g. catheter-like, means
    • A61B2017/003—Steerable
    • A61B2017/00318—Steering mechanisms
    • A61B2017/00331—Steering mechanisms with preformed bends
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053—Mechanical features of the instrument of device
    • A61B2018/00059—Material properties
    • A61B2018/00071—Electrical conductivity
    • A61B2018/00083—Electrical conductivity low, i.e. electrically insulating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00595—Cauterization
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/1206—Generators therefor
    • A61B2018/1246—Generators therefor characterised by the output polarity
    • A61B2018/126—Generators therefor characterised by the output polarity bipolar

Definitions

  • the present invention relates to a bipolar type medical electrode system, and more particularly, by configuring a hard catheter to be capable of bending and manipulating a hard catheter without changing the length of the tip, it is possible to maintain sufficient rigidity of the catheter in the body, thereby eliminating the need for catheters during surgery. It relates to a bipolar type medical electrode system that effectively prevents deformation to ensure safety and convenience of operation.
  • a lesion occurs in a body organ, it is treated as a surgical operation or procedure.
  • the procedure can be generally understood as a concept of a non-surgical method, and since such a non-surgical procedure has a lower risk compared to a surgical method, a lower incidence of surgical trauma, and can be performed relatively simply, a surgical operation must be performed. Except for indications that require surgery, non-surgical methods are often used.
  • treatment using a high-frequency electrode may be exemplified.
  • Treatment using high-frequency electrodes involves inserting high-frequency electrodes into the body for various examinations, cauterization of lesions, drainage of retentions in body cavities or various organs, aspiration of perfusate for washing, measurement of cardiovascular dynamics or central venous pressure, contrast media, etc. It is a concept that includes procedures that perform drug injection, etc., and is widely used in various medical fields.
  • instruments used in high-frequency procedures have a structure for passing electricity to lesions while being inserted into fine human tissues such as blood vessels without difficulty, largely, a small-diameter tubular shaft, a handpiece supporting the shaft, and It is exemplified as including a high-frequency generator for supplying high-frequency alternating current to the shaft.
  • a shape memory alloy guide wire whose tip is bent in an arc shape is installed on the shaft, and as the operator manipulates the guide wire, the guide wire is exposed to the tip of the shaft and bent in an arc shape, so that it is difficult to access the lesion area.
  • a structure that allows access to the electrode tip was common.
  • the length of the tip of the shaft increases or decreases, and the depth of insertion of the shaft into the treatment site must be adjusted in consideration of the change in the length of the tip of the shaft. It was difficult to use, and in addition, sufficient rigidity could not be imparted to the part elongated by the guide wire, so there was a problem in that the treatment effect was reduced in indications where the electrode tip had to be operated in airtight contact with the hard tissue.
  • An object of the present invention is to provide a bipolar type medical electrode system that effectively prevents unnecessary deformation and guarantees the safety and convenience of the procedure.
  • the present invention is made in the form of a tube made of conductive material, once a portion is segmented and divided into a first shaft and a second shaft, and the outer circumferential surface is covered by an insulator, but the second shaft exposed from the insulator
  • the active electrode is coupled so as to be exposed to the outside of the second shaft, and is coupled to a housing made of ceramic material in which a vertical tube and a horizontal tube are bent and jointed in an 'L' shape, and an end of the vertical tube of the housing to be exposed to the outside of the housing. It is characterized in that it includes; an electrode tip that is exposed.
  • the electrode tip a plate-shaped electrode plate mounted to close the end of the open vertical tube; and an electrode body coupled to the electrode plate and exposed to the outside.
  • the electrode body a support; and a cylindrical electrode drum rotatably coupled to the support.
  • a rotating shaft coupled to the vertical pipe is formed on the electrode plate, and the electrode body is formed on one side and the other side of the electrode plate, respectively.
  • the core elastically supports the hard first and second shafts made of metal or the like, when the second shaft is pulled through the traction wire, one end of the catheter can be bent at a certain angle, making it difficult to access.
  • the length of the catheter is not accompanied by deformation, and due to the rigidity of the first and second shafts, it has sufficient deformation resistance in the body. , the operation response of the catheter can be made more intuitive, and thus, the convenience and precision of the operation can be guaranteed.
  • FIG. 1 is a view showing the overall external configuration of a bipolar type medical electrode system according to the present invention.
  • Figure 2 is a view schematically showing the disassembly of main parts of the bipolar type medical electrode system according to the present invention.
  • Figure 3 is a view schematically showing the cross-sectional configuration of the main part of the bipolar type medical electrode system according to the present invention.
  • Figure 4 is a view showing the components embedded in the core and each accommodating hole by way of example.
  • FIG. 5 is a view showing an exploded structure of a first shaft and a second shaft
  • Figure 6 is a view showing the bending action of the catheter.
  • FIG. 7 is a diagram showing an example of an active electrode.
  • FIG. 8 schematically shows a cross-sectional configuration of one end of a catheter to which the active electrode of FIG. 7 is applied.
  • FIG. 9 is a diagram showing an example of an active electrode.
  • FIG. 10 schematically shows a cross-sectional configuration of one end of a catheter to which the active electrode of FIG. 9 is applied.
  • FIG. 11 is a diagram illustrating a process of rotationally moving an electrode tip.
  • the bipolar type medical electrode system (hereinafter referred to as the electrode system) according to the present invention not only functions for cauterization (stomach surgery) such as incision of tissue and hemostasis, but also various examinations, internal organs and body cavities. It is revealed that it can be used for various procedures such as discharge of congested water, aspiration of perfusate for washing, measurement of cardiovascular dynamics or central venous pressure, and drug injection such as contrast agent. let me explain
  • the electrode system according to the present invention includes a catheter 100, an active electrode 300, a traction wire 500, a high frequency generator (not shown), a passive connection wire 200, It can be defined as including the active connection wire 400 and the core 600.
  • the catheter 100 is configured to be inserted into a lesion site in the body during a procedure using an electrode system, and is detachably provided at one end of a handpiece (not shown). Afterwards, remounting on the handpiece can be made.
  • the catheter 100 is made in the form of a tube made of a conductive material, and once a portion is segmented, it is divided into a first shaft 110 and a second shaft 120, and the outer circumferential surface is covered by an insulator 130, the insulator A passive electrode 121 is configured as one end portion of the second shaft 120 exposed from 130.
  • first shaft 110 and the second shaft 120 can be configured to be completely separated from each other, and in the case of the insulator 130 can completely cover the first shaft 110, and the second shaft 120 One end of the part is exposed to the outside and has a configuration so that electrical stimulation is applied to the lesion.
  • a portion of the second shaft 120 exposed from the insulator 130 is referred to as a passive electrode 121 .
  • the active electrode 300 and the passive electrode 121 in this description may be an anode or a cathode according to convenience.
  • the first shaft 110 and the second shaft 120 configured to be completely separated may be coupled and supported to each other by a core 600 to be described later.
  • An inlet 111 is formed through the outer circumferential surface of the other side of the first shaft 110, so that a fluid transfer pipe 700 to be described later can be penetrated into the catheter 100 through the inlet 111.
  • the second shaft 120 may be electrically connected to the passive terminal of the high frequency generator through the passive connection wire 200 wired inside the catheter 100 .
  • the active electrode 300 is coupled to the passive electrode 121, which is one end of the second shaft 120.
  • the active electrode 300 is an active connection wire wired inside the catheter 100. It can be electrically connected to the active terminal of the high frequency generator through 400.
  • the high frequency generator serves to activate a high frequency region around the catheter 100 by applying a high frequency alternating current to the catheter 100 coupled to the handpiece.
  • the high-frequency generator can adopt the concept of a high-frequency generator widely used in general electrical procedures as it is in the line that generates high-frequency alternating current.
  • the conductive wire 200 is connected to supply high-frequency alternating current to the active electrode 300 and the passive electrode 121 .
  • a high frequency region 200 is generated between the active electrode 300 and the passive electrode 121.
  • ⁇ 1200 kHz alternating current propagates.
  • frictional energy caused by ion vibration raises the temperature of living tissue such as blood vessels and tumors, inducing coagulative necrosis, thereby occluding bleeding blood vessels or cauterizing tumors.
  • the bipolar electrode is used as in the present invention, since a delivery path is formed locally only between the active electrode 300 and the passive electrode 121, there is an advantage in not causing side effects to other tissues or blood vessels.
  • a temperature sensor may be coupled to the second shaft 120 or the active electrode 300 to measure the temperature of tissue in the body to be cauterized in a high frequency region in real time.
  • a detailed structure of the active electrode 300 will be described later.
  • the traction wire 500 pulls the second shaft 120 to the other side according to the operator's traction operation so that one end of the catheter 100 is bent at a certain angle to position the electrode at the lesion site that is difficult to access. It is a configuration that allows
  • the traction wire 500 is embedded in the catheter 100, one end is fixed to the inside of the second shaft 120 and the other end is exposed to the other end of the first shaft 110 and can be coupled to the handpiece.
  • the operator can control the traction wire 500 coupled to the handpiece through manual manipulation.
  • the core 600 is coupled between the first shaft 110 and the second shaft 120, which are separated from each other, and made of an elastically deformable material, as shown in FIG. 6, by the traction wire 500.
  • the second shaft 120 is elastically supported on the first shaft 110 by being elastically deformed in response thereto.
  • the separated first shaft 110 and the second shaft 120 can be supported in both directions by the core 600, and the second shaft 120 is pulled backward according to the pulling wire 500. Even if it is, it is possible to maintain the two-way coupled state of the first shaft 110 and the second shaft 120 by being bent curvedly.
  • the core 600 is made of an insulating material to prevent a short circuit between the first shaft 110 and the second shaft 120, thereby preventing conduction of the high-frequency alternating current applied to the passive electrode 121 to the first shaft 110 do.
  • the core 600 When the traction force of the traction wire 500 is removed, the core 600 is restored to its original state by the elastic restoring force and places the first shaft 110 and the second shaft 120 on a straight line.
  • the core 600 may be formed in a cylindrical shape, and a plurality of accommodating holes 610 may be formed therethrough along an axial direction.
  • a passive connection wire 200, an active connection wire 400, a traction wire 500, a fluid transfer pipe 700, etc. may pass through each accommodating hole 610. Accordingly, the core 600 does not interfere with the configuration of each connection wire, traction wire 500, fluid transfer pipe 700, and the like.
  • a certain portion of the lower side of one end of the first shaft 110 may be cut to form a cutout groove 112. Accordingly, as shown in FIG. 6, the first shaft 110 Even if the second shaft 120 is inclined at a certain angle on the top, the first shaft 110 and the second shaft 120 do not interfere with each other, and at the same time, the second shaft in the opposite direction shown in FIG. 6 ( 120) is equipped with a structure capable of limiting the inclined movement.
  • the one end of the catheter 100 is not bent in an irregular direction, but is always bent in the same direction, so that the safety of the procedure can be guaranteed.
  • the fluid transfer tube 700 is connected to a separate fluid injection device to provide a passage for injecting fluid into the body through the active electrode 300, or conversely, it is connected to a separate suction device to suck in and discharge substances in the body. provides an avenue for
  • Fluids necessary for procedures can be moved through the fluid transfer pipe 700 .
  • the fluid transfer tube 700 is integrally coupled with the catheter 100 so that it can be handled together with the catheter 100. Accordingly, when the catheter 100 is removed from the handpiece after the procedure is completed, the catheter 100 is integrally combined with the catheter 100. It becomes a structure that can be removed.
  • the fluid transfer tube 700 extends to the active electrode 300 across the inside of the catheter 100 through the inlet 111, and has a structure that is completely sealed inside the catheter 100, so that it is not introduced into the body during the procedure. It has a structure that is not exposed, and even in the case of fluid flowing in the fluid pipe 700, it does not leak into the catheter 100 and is sealed in the fluid pipe 700 to be injected into the body or discharged from the body. structure will be in place.
  • One end of the fluid pipe 700 may be connected to the active electrode 300 and the other end may be directly connected to an injection device or a suction device. When injected into the body, this fluid is pressurized up to the active electrode 300, flows out around the active electrode 300, and can be injected into the body.
  • the active electrode 300 is largely coupled to be exposed to the outside of the second shaft 120, and a ceramic material in which the vertical pipe 311 and the horizontal pipe 312 are bent and joined in an 'L' shape. It may be defined as including a housing 310 of the housing 310 and an electrode tip 320 coupled to an end of the vertical tube 311 of the housing 310 and exposed to the outside of the housing 310.
  • the 'L'-shaped mounting hole 313 into which one end of the fluid transfer tube 700 is inserted into the vertical tube 311 and the horizontal tube 312 and the 'L'-shaped wire insertion hole 311a, 312a) may be formed.
  • a vertical conductor 314 forming a contact point between the active connection conductor 400 and the electrode tip 320 may be installed in the conductor insertion hole 311a of the vertical tube 311 .
  • the active connection wire 400 is inserted into the wire insertion hole 312a of the horizontal tube 312 of the housing 310, and the wire is inserted into the vertical tube 311 at the bending point of the horizontal tube 312 and the vertical tube 311.
  • a contact may be formed by contacting the vertical conductor 314 wired in the hole 311a.
  • the electrode tip 320 is electrically connected to the high frequency generator.
  • the reason why the active connection wire 400 and the vertical wire 314 are contacted inside the 'L' shaped wire insertion holes 311a and 312a is that the size of the active electrode 300 itself is very narrow. This is because the wire for electrical connection with the electrode tip 320 could not be easily bent inside the housing 310 .
  • an alternating current is applied to the electrode tip 320 without a specially bent wire structure.
  • a structure that can be applied is provided.
  • the fluid pipe 700 It has a structure that can accurately flow out of not only the fixation action but also other chemical liquids to the high-frequency area activation area without backflow, so you can expect even the accuracy of the procedure.
  • the electrode tip 320 is coupled to the plate-shaped electrode plate 321 mounted to close the end of the open vertical tube 311 and the electrode plate 321 to the outside. It may be exemplified as including the exposed electrode body 322 .
  • the electrode plate 321 and the electrode body 322 may be integrally made of a conductive metal material.
  • the vertical conductor 314 may be connected on the electrode plate 321 .
  • An outflow hole 321a communicating with the mounting hole 313 may be formed through the electrode plate 321 . Accordingly, the fluid flowing in the fluid pipe 700 may flow out from the outside of the active electrode 300 and be injected into the body.
  • the electrode body 322 may be exemplified in the form of a protrusion or the like so as to directly apply frictional stimulation to a lesion site in addition to electrical stimulation.
  • the electrode body 322 slides more smoothly on the surface of the bone having an irregular surface structure when in contact with hard tissue such as bone, so that excessive friction beyond the level of treatment or damage to the bone is not applied.
  • the electrode body 322 may have a structure including a support 322a and a cylindrical electrode drum 322b rotatably coupled to the support 322a as shown in FIG. 7 . there is.
  • the support 322a may be fixedly coupled to the electrode plate 321 and may have a structure such as a fixed bearing on a line capable of rotatably supporting the electrode drum 322b.
  • the electrode drum 322b has a configuration in direct contact with the lesion, and is in contact with the surface of the lesion in a rolling manner, and in the process of the electrode tip 320 sweeping the surface of the lesion, it flexibly contacts the surface of the lesion without frictional resistance. It can be.
  • the electrode drum 322b may be hollow as shown in FIG. 7A or solid as shown in FIG. 7B.
  • the electrode body 322 is formed on one side and the other side of the electrode plate 321 as a different dimension, and the electrode tip 320 is rotated according to circumstances to form one of the pair of electrode plates 321. By exposing and using at least one of them to the outside, it has a structure in which various parts can be effectively treated without replacing the electrode body 322 individually.
  • the electrode body 322 of different specifications means that when the electrode body 322 has a protrusion shape, the size and number of the protrusions are different from each other, and in the case of the above-described embodiment, the electrode drum 322b
  • the diameter, length, etc. of may mean different things.
  • a rotational shaft 321b shaft-coupled to the vertical tube 311 may be formed in the electrode plate 321, and a shaft support 311c supporting the rotational shaft 321b is formed at a lower end of the vertical tube 311. ) can be formed.
  • the electrode tip 320 itself can rotate in place with respect to the rotating shaft 321b, and when at least one of the pair of electrode bodies 322 is exposed to the outside of the vertical tube 311, the other electrode
  • the sieve 322 is equipped with a structure accommodated inside the vertical tube 311.
  • a locking pin 323 may be fastened by mutually penetrating the vertical tube 311 and the electrode plate 321.
  • a first pin insertion hole 321c may be formed through the electrode plate 321 in a direction crossing the rotating shaft 321b, and a second pin insertion hole 321c communicating with the first pin insertion hole 321c may be formed in the vertical pipe 311.
  • a pin insertion hole 311b may be formed.
  • the rotational movement of the electrode tip 320 may be restricted in the fixed position.
  • the active connection wire 400 has a structure that is directly connected to the rotating shaft 321b so that AC supply is possible even when the electrode tip 320 is rotated.
  • the rotating shaft 321b and the active connecting wire 400 are connected via a swivel joint to have a structure that prevents the active connecting wire 400 from being twisted even when the electrode tip 320 is rotated.
  • the core elastically supports the hard first and second shafts made of metal, etc.
  • one end of the catheter when the second shaft is pulled through the traction wire, one end of the catheter can be bent at a certain angle, It is possible to place the electrode in a lesion area that is difficult to access, and when one end of the catheter is bent, the length of the catheter is not deformed. Also, due to the rigidity of the first and second shafts, sufficient deformation resistance is resisted in the body. As a result, the catheter manipulation response can be made more intuitive, and thus, the convenience and precision of the procedure can be guaranteed.

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Abstract

La présente invention concerne un système d'électrodes bipolaires à usage médical et, plus spécifiquement, un système d'électrodes bipolaires à usage médical, dans lequel, par la configuration d'un cathéter dur à manipuler de manière flexible sans changement de la longueur de l'extrémité avant, le cathéter peut maintenir une rigidité suffisante dans le corps, empêchant ainsi efficacement une déformation inutile pendant une procédure pour assurer une sécurité procédurale et une commodité procédurale.
PCT/KR2022/014815 2021-10-28 2022-09-30 Système d'électrodes bipolaires à usage médical WO2023075186A1 (fr)

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KR10-2021-0145385 2021-10-28
KR1020210145385A KR102665235B1 (ko) 2021-10-28 2021-10-28 바이폴라 방식의 의료용 전극시스템

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KR20120074516A (ko) * 2010-12-28 2012-07-06 (주)트리플씨메디칼 전류-회전식 수술기구
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