WO2022169246A1 - Composition de matière cosmétique - Google Patents
Composition de matière cosmétique Download PDFInfo
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- WO2022169246A1 WO2022169246A1 PCT/KR2022/001637 KR2022001637W WO2022169246A1 WO 2022169246 A1 WO2022169246 A1 WO 2022169246A1 KR 2022001637 W KR2022001637 W KR 2022001637W WO 2022169246 A1 WO2022169246 A1 WO 2022169246A1
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- hair
- cosmetic composition
- skin
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- cells
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Classifications
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
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- A—HUMAN NECESSITIES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K8/447—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof containing sulfur
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
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Definitions
- the cosmetic composition according to the present invention comprises at least one selected from the group consisting of thiamine, pyridoxine, folic acid, cyanocobalamin, glycyrrhetinic acid, aluminum sucrose octasulfate, lupeol and carnosine as an active ingredient. characterized.
- folic acid and pharmaceutically acceptable salts of folic acid When folic acid and pharmaceutically acceptable salts of folic acid are applied to the skin, it increases the cell proliferation ability of the skin, the collagen synthesis ability of the skin cells, the moisture content of the skin cells, the amount of collagen 7 synthesis in the skin cells, and the production of antibacterial peptides. , has the effect of inhibiting the synthesis of melanin in melanocytes.
- folic acid can be obtained from grains, vegetables, and fruits, but can also be purchased and used in domestic and overseas markets.
- cyanocobalamin may be included in an amount of 1,000 ppm or less.
- the content of cyanocobalamin is preferably 1,000 ppm or less, and most preferably 100 ppm or less.
- the cosmetic composition according to the present invention is a lotion, facial lotion, body lotion, nourishing cream, moisture cream, eye cream, essence, cosmetic ointment, spray, gel, pack, sunscreen, makeup base, foundation, powder, cleansing cream, cleansing lotion , cleansing oil, cleansing foam, soap or body wash formulation.
- the composition of the present invention may include a carrier for the active ingredient.
- the carrier is, for example, animal oil, vegetable oil, wax, paraffin, starch, cellulose derivatives such as tracanth, hydroxyethyl, polyethylene glycol, silicone, bentonite, silica, talc, zinc oxide, cetostearyl alcohol or chloride It may be stearyltriethylammonium, but is not limited thereto. These may be used alone or in combination of two or more.
- the composition of the present invention may include a carrier for the active ingredient.
- the carrier may be, for example, an alkali metal salt of a fatty acid, a fatty acid hemiester salt, a fatty acid protein hydrolyzate, isethionate, a lanolin derivative, an aliphatic alcohol, vegetable oil, glycerol, sugar, etc., but is limited thereto. it's not going to be These may be used alone or in combination of two or more.
- the cosmetic composition according to the present invention can increase the expression rate of hyaluronic acid synthase in skin cells. Accordingly, the moisture content in the skin cells is increased, providing an effect of moisturizing and providing elasticity to the skin.
- the cosmetic composition according to the present invention increases the amount of collagen 7 synthesis in skin cells. Accordingly, it provides a protective effect through the structure and maintenance of the skin barrier by improving the structural retention and wound regeneration of the epidermis and dermis.
- the cells were recovered by treatment with 0.25% trypsin (Gibco BRL, USA) and cultured.
- a 96-well culture plate (Falcon Co) 1 x 10 4 cells were dispensed per sugar and cultured for 1 day.
- each active ingredient was mixed with DMEM according to the experimental concentration in Table 1 below, put into each well, and incubated for 24 hours again, after which 10 ⁇ l of CCK-8 solution was added to each well, % CO 2 was reacted for 1 hour in a donated cell incubator. And absorbance was measured at 450 nm by ELISA reade.
- melanocyte B16 Dulbecco's modified containing penicillin (100 IU/ml), streptomycin (100 ⁇ g/ml) (GibcoBRL, USA) and 10% fetal bovine serum (FBS, GibcoBRL, USA).
- eagles medium DMEM, GibcoBRL, USA
- DMEM fetal bovine serum
- HBD2 human beta defensin2
- HRP horseradish peroxidase
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
Abstract
La présente invention se rapporte à une composition de matière cosmétique qui est sûre pour le corps humain, améliore l'état de la peau, et a des effets cosmétiques, caractérisée en ce qu'elle comprend, en tant que principe actif, au moins un type choisi dans le groupe constitué par la thiamine, la pyridoxine, l'acide folique, la cyanocobalamine, l'acide glycyrrhétinique, l'aluminium sucrose octasulfate, le lupéol, la carnosine et leurs sels pharmaceutiquement acceptables.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202280008760.XA CN116669694A (zh) | 2021-02-02 | 2022-01-28 | 化妆料组合物 |
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| KR10-2021-0014904 | 2021-02-02 | ||
| KR20210014904 | 2021-02-02 |
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| WO2022169246A1 true WO2022169246A1 (fr) | 2022-08-11 |
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| Application Number | Title | Priority Date | Filing Date |
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| PCT/KR2022/001637 WO2022169246A1 (fr) | 2021-02-02 | 2022-01-28 | Composition de matière cosmétique |
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| Country | Link |
|---|---|
| KR (1) | KR20220111677A (fr) |
| CN (1) | CN116669694A (fr) |
| WO (1) | WO2022169246A1 (fr) |
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| WO2024106669A1 (fr) * | 2022-11-18 | 2024-05-23 | 주식회사 엘지생활건강 | Composition visant à atténuer les rides cutanées |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20110060800A (ko) * | 2009-11-30 | 2011-06-08 | (주)아모레퍼시픽 | 세포 외 기질을 모사한 피부 세포 재생용 화장료 조성물 |
| KR101042712B1 (ko) * | 2011-02-11 | 2011-06-20 | 주식회사 씨앤피차앤박화장품 | 피부 재생 및 상처 치유용 화장료 조성물 |
| KR101813124B1 (ko) * | 2017-06-07 | 2018-01-30 | 주식회사 코리아나화장품 | 세포신호전달 물질인 시그날로좀을 유효성분으로 함유하는 화장료 조성물 |
| KR20190100141A (ko) * | 2018-02-08 | 2019-08-28 | 주식회사 엘지생활건강 | 광산란 감소 물질을 포함하는 피부 광특성 개선용 조성물 |
| WO2020040621A1 (fr) * | 2018-08-23 | 2020-02-27 | 주식회사 엘지생활건강 | Composition visant à favoriser la différenciation ou la prolifération de cellules souches adipeuses humaines |
-
2022
- 2022-01-28 KR KR1020220013659A patent/KR20220111677A/ko unknown
- 2022-01-28 WO PCT/KR2022/001637 patent/WO2022169246A1/fr active Application Filing
- 2022-01-28 CN CN202280008760.XA patent/CN116669694A/zh active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20110060800A (ko) * | 2009-11-30 | 2011-06-08 | (주)아모레퍼시픽 | 세포 외 기질을 모사한 피부 세포 재생용 화장료 조성물 |
| KR101042712B1 (ko) * | 2011-02-11 | 2011-06-20 | 주식회사 씨앤피차앤박화장품 | 피부 재생 및 상처 치유용 화장료 조성물 |
| KR101813124B1 (ko) * | 2017-06-07 | 2018-01-30 | 주식회사 코리아나화장품 | 세포신호전달 물질인 시그날로좀을 유효성분으로 함유하는 화장료 조성물 |
| KR20190100141A (ko) * | 2018-02-08 | 2019-08-28 | 주식회사 엘지생활건강 | 광산란 감소 물질을 포함하는 피부 광특성 개선용 조성물 |
| WO2020040621A1 (fr) * | 2018-08-23 | 2020-02-27 | 주식회사 엘지생활건강 | Composition visant à favoriser la différenciation ou la prolifération de cellules souches adipeuses humaines |
Also Published As
| Publication number | Publication date |
|---|---|
| CN116669694A (zh) | 2023-08-29 |
| KR20220111677A (ko) | 2022-08-09 |
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