WO2022054461A1 - 噴霧乾燥装置 - Google Patents

噴霧乾燥装置 Download PDF

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Publication number
WO2022054461A1
WO2022054461A1 PCT/JP2021/028581 JP2021028581W WO2022054461A1 WO 2022054461 A1 WO2022054461 A1 WO 2022054461A1 JP 2021028581 W JP2021028581 W JP 2021028581W WO 2022054461 A1 WO2022054461 A1 WO 2022054461A1
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Prior art keywords
mist
ultrasonic
ultrafine
solute
spray
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2021/028581
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English (en)
French (fr)
Japanese (ja)
Inventor
康司 川崎
嘉貴 緒方
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Acous Corp
Original Assignee
Airex Co Ltd
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Priority to JP2022547441A priority Critical patent/JP7717391B2/ja
Publication of WO2022054461A1 publication Critical patent/WO2022054461A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D1/00—Evaporating
    • B01D1/16—Evaporating by spraying
    • B01D1/18—Evaporating by spraying to obtain dry solids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D1/00—Evaporating
    • B01D1/16—Evaporating by spraying
    • B01D1/20—Sprayers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04C—APPARATUS USING FREE VORTEX FLOW, e.g. CYCLONES
    • B04C3/00—Apparatus in which the axial direction of the vortex flow following a screw-thread type line remains unchanged ; Devices in which one of the two discharge ducts returns centrally through the vortex chamber, a reverse-flow vortex being prevented by bulkheads in the central discharge duct
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04C—APPARATUS USING FREE VORTEX FLOW, e.g. CYCLONES
    • B04C3/00—Apparatus in which the axial direction of the vortex flow following a screw-thread type line remains unchanged ; Devices in which one of the two discharge ducts returns centrally through the vortex chamber, a reverse-flow vortex being prevented by bulkheads in the central discharge duct
    • B04C3/02—Apparatus in which the axial direction of the vortex flow following a screw-thread type line remains unchanged ; Devices in which one of the two discharge ducts returns centrally through the vortex chamber, a reverse-flow vortex being prevented by bulkheads in the central discharge duct with heating or cooling, e.g. quenching, means
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B17/00—Machines or apparatus for drying materials in loose, plastic, or fluidised form, e.g. granules, staple fibres, with progressive movement
    • F26B17/10—Machines or apparatus for drying materials in loose, plastic, or fluidised form, e.g. granules, staple fibres, with progressive movement with movement performed by fluid currents, e.g. issuing from a nozzle, e.g. pneumatic, flash, vortex or entrainment dryers

Definitions

  • the present invention relates to a spray drying device that separates a solute and a solvent from a solution and recovers the solute as a fine particle powder, and more particularly to a spray drying device capable of avoiding denaturation, decomposition, deterioration, etc. of the solute component. Is.
  • a spray dryer also referred to as a spray dryer
  • the spray dryer conventionally used is usually dried in a high temperature atmosphere of 150 ° C. or higher, there is a problem that the solute dissolved in the solution is denatured, decomposed and deteriorated by the high temperature.
  • heat-sensitive components such as proteins, vitamins, and pharmaceuticals are often handled, and it is difficult to dry them without denaturation, decomposition, or deterioration.
  • freeze-drying method a method of drying at a low temperature of ⁇ 180 to ⁇ 10 ° C.
  • the drying time is long, it is difficult to obtain a sufficient dried product, and there is a problem in the stability of the operation.
  • the equipment used for the freeze-drying method has become large, and there are problems with equipment costs and running costs.
  • Patent Document 1 a spray dryer that can avoid denaturation, decomposition, deterioration, etc. of solute components and reduce equipment costs and running costs is proposed.
  • this spray dryer the liquid to be dried atomized by the ultrasonic atomizer is sprayed into the vacuum chamber, dried by the heating means provided on the side surface in the vacuum chamber, and the fine particles are separated and collected by the dust collector. It is to do.
  • Patent Document 1 since the liquid to be dried is atomized by an ultrasonic atomizer and then dried, it seems that the fine particles are dried and the drying is performed promptly. Further, the temperature in the vacuum chamber is as low as 20 to 80 ° C. during operation, and it seems that denaturation, decomposition, deterioration and the like of solute components can be avoided. However, the surface temperature of the heating means provided on the side surface in the vacuum chamber is not clear, and since the vacuum is used, heat conduction is poor and it is difficult to sufficiently transfer heat from the heating means.
  • the mist of the atomized liquid to be dried adheres to and accumulates on the heating means in the vacuum chamber, and heat denaturation, decomposition, deterioration and the like may occur on this surface.
  • the equipment cost of the vacuum chamber itself and the decompression equipment becomes a problem.
  • the drying temperature can be lowered and the drying time can be shortened, and the ultrafine mist can be used as an apparatus. It is an object of the present invention to provide a spray drying apparatus capable of obtaining fine and uniform fine particle powder without adhering and accumulating on the inner wall surface and avoiding modification, decomposition, deterioration and the like of solute components.
  • An ultrasonic spray unit (20) that converts a solution consisting of a solute of a solid component and a solvent of a liquid component into ultrafine mist (26) and supplies it, and vaporizes the solvent from the supplied ultrafine mist to make the solute fine. It has a powder recovery unit (30) that recovers as a solid powder.
  • the ultrasonic spray unit includes a mist discharging means (50) that converts the solution into a primary mist (25) and discharges the solution, and a convergent ultrasonic generating means that further refines the primary mist and converts it into an ultrafine mist.
  • the powder recovery unit includes a heating gas supply means for supplying a heating gas for heating ultrafine mist, and a separation and recovery means (40) for separating the vaporized solvent and the solute to recover the solute.
  • the convergent ultrasonic wave generating means is provided with a plurality of vibration discs (61a to 61d) in the vicinity of the discharge port of the mist discharging means, and the plurality of vibrating discs are ultrasonically vibrated in the same phase in the vertical direction from each board surface.
  • a directional ultrasonic acoustic flow (62a to 62d) is generated by sound waves, and the directing direction of each ultrasonic acoustic flow converges in front of the discharge direction of the primary mist discharged from the discharge port of the mist discharge means.
  • the mist discharging means is a mist generator using a spray nozzle such as a one-fluid nozzle or a two-fluid nozzle, a rotary spray device, or an ultrasonic atomizer such as a nebulizer.
  • the spray drying apparatus according to the first or second aspect of the present invention.
  • the separation / recovery means comprises a cyclone separator, and the heating gas supplied from the heating gas supply means is introduced from the direction of the inner wall tangent of the cyclone body, and the heating gas and the ultrafine mist are separated by the vortex flow. It is characterized by contacting and exchanging heat to evaporate the solvent, and separating the mixed gas of the heating gas and the vaporized solvent and the solid solute.
  • the present invention is the spray drying device according to claim 3.
  • the separation / recovery means ultrasonically vibrates a plurality of vibration discs (41a to 41d) arranged so that the board surface faces the central portion of the upper inner wall surface of the cyclone body, and ultrasonic waves are generated in the vertical direction from each board surface. Generates an acoustic flow (42a-42d) to generate It is characterized in that the ultrafine mist supplied to the cyclone body is pressed by an ultrasonic acoustic flow from the surroundings to maintain the fine state of the ultrafine mist and promote the vaporization of the solvent.
  • the spray drying device has an ultrasonic spray unit and a powder recovery unit.
  • the ultrasonic spray unit converts a solution consisting of a solute of a solid component and a solvent of a liquid component into ultrafine mist and supplies it.
  • the powder recovery unit vaporizes the solvent from the supplied ultrafine mist and recovers the solute as fine powder.
  • the ultrasonic spray unit includes a mist discharging means that converts a solution into a primary mist and discharges the solution, and a convergent ultrasonic generating means that further refines the primary mist and converts it into an ultrafine mist.
  • the powder recovery unit includes a heating gas supply means for supplying a heating gas for heating the ultrafine mist, and a separation and recovery means for separating the vaporized solvent and the solute to recover the solute.
  • the convergent ultrasonic generation means is provided with a plurality of vibration discs in the vicinity of the discharge port of the mist discharge means, and the plurality of vibration discs are ultrasonically vibrated in the same phase in the vertical direction from each board surface. Generates a directional ultrasonic acoustic flow by ultrasonic waves. A plurality of vibrating discs are arranged so that the directivity direction of these ultrasonic acoustic flows converges in front of the discharge direction of the primary mist discharged from the discharge port of the mist discharge means. As a result, the primary mist discharged from the discharge port of the mist discharge means is converted into ultrafine mist, and the ultrafine mist is supplied to the powder recovery unit by pressing the converged ultrasonic acoustic flow.
  • the drying temperature can be lowered and the drying time can be shortened, and the ultrafine mist adheres and accumulates on the inner wall surface of the apparatus. It is possible to provide a spray drying apparatus capable of avoiding modification, decomposition, deterioration and the like of solute components and obtaining fine and uniform fine particle powder.
  • the mist discharging means may be a spray nozzle such as a one-fluid nozzle or a two-fluid nozzle, a rotary spray device, or a mist generator by an ultrasonic atomizer such as a nebulizer. This makes it possible to exert the above-mentioned action and effect more concretely.
  • the separation / recovery means comprises a cyclone separator, and the heating gas supplied from the heating gas supply means is introduced from the direction tangential to the inner wall of the cyclone body. Due to the introduced vortex of the heating gas, the heating gas and the ultrafine mist come into contact with each other and exchange heat to evaporate the solvent. Then, the mixed gas of the heating gas and the vaporized solvent and the solid solute are separated. This makes it possible to exert the above-mentioned action and effect more concretely.
  • the separation / recovery means ultrasonically vibrates a plurality of vibrating discs arranged so that the board surface faces the center of the upper inner wall surface of the cyclone body, and ultrasonically vibrates from each board surface in the vertical direction. Generates an ultrasonic acoustic flow. The pressing by this ultrasonic acoustic flow acts on the ultrafine mist supplied to the cyclone body from the surroundings. This maintains the fine state of the ultrafine mist and promotes the vaporization of the solvent. This makes it possible to exert the above-mentioned action and effect more concretely.
  • FIG. 1 It is a front view which shows the appearance of the spray drying apparatus which concerns on this invention. It is a perspective view of the structural conceptual diagram which shows the inside of the ultrasonic spray unit of the spray drying apparatus of FIG. It is a structural conceptual diagram which shows the inside of the powder recovery unit of the spray drying apparatus of FIG. 1, (A) front view, (B) XX sectional view.
  • the solute and the solvent can be separated from the solution consisting of the solute of the solid component and the solvent of the liquid component, and the solute can be recovered as a fine and uniform fine particle powder.
  • the solute can be recovered as a fine and uniform fine particle powder.
  • heat-sensitive components such as proteins, vitamins, and pharmaceuticals in fields such as pharmaceutical manufacturing and food manufacturing. It can also be used for natural product extracts, fragrances, powdered fats and oils, pigments, chemical products, inorganic substances and the like.
  • the term “mist” in the present invention will be described.
  • the term “mist” is broadly interpreted, and is a state of droplets that are atomized and suspended in the air, a state in which gas and droplets are mixed, and a state of gas and droplets. It shall include the state where the phase change between condensation and evaporation is repeated between them.
  • it when explaining such a broad concept of "mist” in detail, it is used properly as “primary mist” and “ultrafine mist” depending on the particle size of the main components constituting the mist. And.
  • the "primary mist” referred to in the present invention is not limited to containing only particles of 10 ⁇ m or less, which is generally defined as mist, but is also defined as “fine droplets” having a particle size larger than that, or generally fog. It also includes particles of 5 ⁇ m or less.
  • Examples of the primary mist generating means include a one-fluid spray nozzle that directly mistizes a liquid, a piezo high-pressure injection device, a disk-type atomizer, and a disk mesh-type atomizer.
  • a one-fluid spray nozzle that directly mistizes a liquid
  • a piezo high-pressure injection device e.g., a piezo high-pressure injection device
  • a disk-type atomizer e.g., a disk-type atomizer
  • a disk mesh-type atomizer ejectors and two-fluid spray nozzles that mist liquids with high-pressure air. When these are used, not only particles of 10 ⁇ m or less but also many “fine droplets” are included.
  • the action of ultrasonic vibration such as a nebulizer or an ultrasonic atomizer
  • particles of 10 ⁇ m or less are the main components (main but not all).
  • the "primary mist” referred to in the present invention mainly includes two types of mist depending on the primary mist generating means used. As will be described later, in the present invention, it is preferable to utilize the action of ultrasonic vibration as the primary mist generating means.
  • the "ultrafine mist” referred to in the present invention means that the primary mist is affected by the action of the convergent ultrasonic generation means (details will be described later) and contains a fog of 5 ⁇ m or less, but is further ultrafine and ultrafine of 3 ⁇ m or less. It refers to those whose main component (main, not all) is homogenized into fine particles. Since the particle size of this ultrafine mist is very small, the surface area is large, and the phase change between condensation and evaporation is actively repeated between the gas and the mist. Therefore, the evaporation of the solvent is promoted by the action of the heat source (heating gas) from the outside, and the solute and the solvent can be easily separated.
  • the heat source heating gas
  • FIG. 1 is a front view showing the appearance of the spray drying device according to the present invention.
  • the spray drying device 10 has an ultrasonic spray unit 20 and a powder recovery unit 30 (details will be described later). Outside the ultrasonic spray unit 20, a solution tank 21, a supply pump 22, and a supply pipe 23 for supplying a solution to a mist discharging means (not shown and described later) are provided. The structure of the ultrasonic spray unit 20 will be described later.
  • the powder recovery unit 30 has a heating gas supply means (not shown) and a separation and recovery means 40.
  • the separation / recovery means 40 is a cyclone separator, and is composed of a mist-drying portion 40a of a straight cylinder at an upper portion and a separation portion 40b of a spindle cylinder at a lower portion.
  • An introduction pipe 43 for introducing the heating gas from the heating gas supply means into the upper part of the mist drying portion 40a is provided.
  • the heating gas is introduced from the introduction pipe 43 from the direction tangential to the inner wall of the mist dry portion 40a to form a vortex inside. This vortex expresses the function of the cyclone separator.
  • each of the vibrating surfaces of these vibrating discs 41a to 41d is arranged from the inner wall surface of the mist drying portion 40a toward the center. The actions of the four vibrating discs 41a to 41d will be described later.
  • a lead-out pipe 44 is provided in which a solid (solute) and a gas (a mixed gas of a vaporized solvent and a heating gas) are separated by a cyclone separation mechanism, and the mixed gas is led out to the outside. ing.
  • the mixed gas led out from the lead-out pipe 44 is cooled by a heat exchanger, separated into a heating gas (details will be described later) and a liquid component solvent, and each is recovered.
  • a recovery container 45 for recovering the recovered solute powder (fine particle powder) is provided below the separation portion 40b.
  • FIG. 2 is a perspective view of a conceptual diagram showing the inside of the ultrasonic spray unit.
  • the ultrasonic spray unit 20 has a mist discharging means 50 and a convergent ultrasonic generating means 60. Note that FIG. 2 shows a state in which the cylindrical outer wall 20a of the ultrasonic spray unit 20 is seen through.
  • an ultrasonic atomizer 50 (only the discharge port is shown in FIG. 2) is adopted as the mist discharge means 50, and the solution 24 sent from the solution tank 21 via the supply pipe 23 is received and finely divided. It is converted into a primary mist 25 and discharged from the discharge port. Therefore, the primary mist 25 is a fine mist containing particles of 10 ⁇ m or less as the main component (mainly, not all).
  • the convergent ultrasonic wave generating means 60 is composed of four vibrating discs 61a to 61d arranged on the upper part of the inner side wall surface of the cylindrical outer wall 20a of the ultrasonic spray unit 20 so as to surround the emission port of the ultrasonic atomizing device 50. There is.
  • the distance from the discharge port of the ultrasonic atomizer 50 to each of the vibrating discs 61a to 61d is not particularly limited.
  • super-directional ultrasonic transmitters DC12V, 50mA that transmit ultrasonic waves having a frequency of around 40 kHz are used as the four vibrating discs 61a to 61d.
  • the number of vibrating discs may be two or more, preferably three or more.
  • the type and number, size and structure, output, etc. of the ultrasonic transmitters arranged in each vibrating panel are not particularly limited.
  • the ultrasonic wave generation mechanism, frequency range, output, etc. of the ultrasonic wave transmitter are not particularly limited.
  • the four vibrating discs 61a to 61d that transmit super-directional ultrasonic waves are located in front of the emission axis of the emission port of the ultrasonic atomizer 50 (below the emission port) and ultrasonically vibrate.
  • the ultrasonic sound currents are attached at an inward angle so that the ultrasonic acoustic waves converge.
  • the inward angle is a mounting angle such that the elevation angle of the ultrasonic acoustic flow is larger than 0 ° and smaller than 90 ° with respect to the discharge axis of the discharge port of the ultrasonic atomizer 50, and is preferable.
  • a mounting angle that is 45 ° or more and 70 ° or less.
  • the four vibrating discs 61a to 61d are ultrasonically vibrated in the same phase to generate directional ultrasonic acoustic flows 62a to 62d from each disc surface in the vertical direction. Further, the wave transmission direction from each board surface is converged in front of the emission axis of the emission port of the ultrasonic atomizer 50 (below the emission port). As a result, the ultrasonic acoustic flows 62a to 62d emitted from the vibrating discs 61a to 61d strengthen each other at the focal point 63 (converging portion 63), and the maximum energy is concentrated in this portion.
  • the fine primary mist 25 of the solution 24 discharged below the ultrasonic spray unit 20 from the discharge port of the ultrasonic atomizer 50 obtains the maximum energy of the concentrated ultrasonic acoustic flow. It is further refined to become the ultrafine mist 26 of the solution 24. Further, the energy of the converged ultrasonic acoustic flow forms the ultrafine mist 26 and causes the ultrafine mist 26 to press the ultrasonic acoustic flow in the mist traveling direction (lower part in the drawing). As a result, the ultrafine mist 26 is extruded in the direction of the arrow 26a and is charged into the powder recovery unit 30 connected to the lower part of the ultrasonic spray unit 20.
  • the ultrafine mist 26 of the solution 24 charged into the powder recovery unit 30 has a small particle size and a large surface area, so that the evaporation efficiency of the mist is high and evaporation and condensation are actively repeated.
  • the ultrafine mist 26 is affected by the action of the heating gas introduced from the outside, and the solvent is easily vaporized so that the solute and the solvent can be separated.
  • the action of the ultrasonic acoustic flows 62a to 62d is not only to make the solution ultrafine, but also to suppress the adhesion of mist to the discharge port of the ultrasonic atomizer 50 and the inner wall surface of the ultrasonic spray unit 20. can.
  • FIG. 3 is a conceptual diagram showing the inside of the powder recovery unit, which is (A) a front view and (B) a sectional view taken along the line XX.
  • the separation / recovery means 40 is a cyclone separator and is composed of a mist-drying portion 40a of a straight cylinder at the upper part and a separation portion 40b of a spindle cylinder at the lower part.
  • each of the vibrating surfaces of these vibrating discs 41a to 41d is arranged from the inner wall surface of the mist drying portion 40a toward the center.
  • super-directional ultrasonic transmitters DC12V, 50mA that transmit ultrasonic waves having a frequency of around 40 kHz are used as the four vibrating discs 41a to 41d.
  • the number of vibrating discs is not limited to four and is not particularly limited.
  • the type and number, size and structure, output, etc. of the ultrasonic transmitters arranged in each vibrating panel are not particularly limited.
  • the ultrasonic wave generation mechanism, frequency range, output, etc. of the ultrasonic wave transmitter are not particularly limited.
  • each vibrating disc The wave transmission direction of each vibrating disc is directed toward the center of the cylinder so that each ultrasonic acoustic flow generated by ultrasonic vibration of the four vibrating discs 41a to 41d converges at the center of the cylinder of the mist drying portion 40a. Is attached. As a result, the ultrasonic acoustic flows 42a to 42d emitted from the vibrating discs 41a to 41d strengthen each other at the center of the cylinder, and the maximum energy is concentrated in this part (see FIG. 3B). ..
  • the ultrafine mist 26 that has been pushed out from the ultrasonic spray unit (not shown) into the mist drying portion 40a by pressing the ultrasonic acoustic flow (arrow 26a) is the ultrasonic acoustic flow 42a.
  • the maximum energy in which ⁇ 42d is concentrated is obtained, and the ultrafine mist does not coalesce with each other, and further miniaturization of the mist and evaporation of the solvent are promoted.
  • the heating gas from the heating gas supply means (not shown) is introduced from the introduction pipe 43 to the upper part of the mist drying portion 40a.
  • the introduction pipe 43 is opened so as to discharge the heating gas from the direction tangential to the inner wall of the mist dry portion 40a.
  • the introduced heating gas forms a vortex flow 46 along the inner wall of the mist-dried portion 40a.
  • This vortex 46 expresses the function of the cyclone separator. Further, since the vortex flow 46 flows downward along the inner wall of the mist dry portion 40a, the ultrafine mist does not adhere and accumulate on the inner wall surface of the powder recovery unit 30.
  • the heating gas gives heat energy to the ultrafine mist to be dried and acts to evaporate the solvent from the solution constituting the ultrafine mist.
  • heated air it is better to use heated air, but in consideration of the properties of the solute to be heated and the solvent, an inert gas such as nitrogen or argon may be used if necessary.
  • heated air is used for the purpose of producing fine particles of pharmaceutical products.
  • the temperature of the heated air was 100 ° C. or lower, preferably 80 ° C. in order to avoid deterioration of the pharmaceutical product.
  • the temperature of the heating gas may be set in consideration of the properties of the object to be dried.
  • the reason why the temperature of the heating gas for drying can be set low and the drying time can be shortened is considered as follows.
  • the solution to be dried receives the concentrated energy of the ultrasonic acoustic flow and becomes hyperfine, and its particle size is small and its surface area is large. It is considered that this increases the evaporation efficiency of the ultrafine mist and easily vaporizes the solvent under the action of the heating gas. As a result, the solute and the solvent can be easily separated.
  • the action of the ultrasonic acoustic flows 42a to 42d can suppress not only the separation of the solute and the solvent but also the adhesion and deposition of the dry solute on the inner wall surface of the powder recovery unit 30.
  • the ultrafine mist 26 and the heating gas exchange heat while being actively mixed and contacted by the vortex 46 of the heating gas, and are solid (solute).
  • And gas mixed gas of vaporized solvent and heating gas.
  • the separated solute is collected as a fine particle powder 47 in a collection container 45 provided below the separation portion 40b.
  • the fine particle powder 47 recovered from the ultrafine mist 26 is a uniform and fine powder, and the particle size can be recovered as about 5 ⁇ m to 0.1 ⁇ m.
  • the solvent is recovered as a mixed gas with the heating gas from the central portion of the cyclone separation mechanism of the mist-dried portion 40a (reference numeral 44a in FIG. 3B) via the lead-out pipe 44.
  • the recovered mixed gas is cooled by a heat exchanger, separated into a heating gas and a solvent of liquid components, and each is recovered and reused.
  • the heat exchanger which is a solvent recovery facility, is a general one and is not mentioned here.
  • the drying temperature can be lowered and the drying time can be shortened, and the ultrafine mist can be used as the inner wall surface of the apparatus. It is possible to provide a spray drying apparatus capable of avoiding modification, decomposition, deterioration and the like of solute components without adhering and accumulating on the surface, and capable of obtaining fine and uniform fine particle powder.
  • the primary mist is supplied by using an ultrasonic atomizer as a mist discharging means.
  • the present invention is not limited to this, and a one-fluid spray nozzle that does not use ultrasonic waves, a piezo high-pressure injection device, a disk-type atomizer, a disk-mesh atomizer, an ejector, a two-fluid spray nozzle, or the like may be used. ..
  • four vibrating discs are provided on the peripheral wall of the mist-dried portion, and an ultrasonic acoustic flow is further applied to the ultrafine mist.
  • the present invention is not limited to this, and a normal cyclone separator may be used without providing a vibrating disc.
  • a cyclone separation mechanism is adopted for the recovery of the solute.
  • the present invention is not limited to this, and other separation mechanisms such as a filter may be adopted.

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Vaporization, Distillation, Condensation, Sublimation, And Cold Traps (AREA)
PCT/JP2021/028581 2020-09-08 2021-08-02 噴霧乾燥装置 Ceased WO2022054461A1 (ja)

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JP2008089235A (ja) * 2006-10-02 2008-04-17 Kigyo Kumiai Shizuoka Kikai Seisakusho 加熱処理装置
JP2010008005A (ja) * 2008-06-30 2010-01-14 Ohkawara Kakohki Co Ltd 微粒子乾燥装置
JP2015232405A (ja) * 2014-06-09 2015-12-24 東京理化器械株式会社 スプレードライヤ
JP2019045114A (ja) * 2017-09-06 2019-03-22 東京理化器械株式会社 噴霧乾燥装置
WO2019231311A1 (en) * 2018-05-31 2019-12-05 POH YOKE, Yong Dehydration and disintegration apparatus and system

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