WO2022033637A1 - Trocknung von filtermodulen und filtergehäusen mit einem frequenzgeführten mikrowellenprozess - Google Patents
Trocknung von filtermodulen und filtergehäusen mit einem frequenzgeführten mikrowellenprozess Download PDFInfo
- Publication number
- WO2022033637A1 WO2022033637A1 PCT/DE2021/100693 DE2021100693W WO2022033637A1 WO 2022033637 A1 WO2022033637 A1 WO 2022033637A1 DE 2021100693 W DE2021100693 W DE 2021100693W WO 2022033637 A1 WO2022033637 A1 WO 2022033637A1
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- WIPO (PCT)
- Prior art keywords
- filter
- microwave
- frequency
- chamber
- power
- Prior art date
Links
- 238000001035 drying Methods 0.000 title claims abstract description 40
- 238000000034 method Methods 0.000 title claims abstract description 27
- 230000008569 process Effects 0.000 title description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 47
- 230000001070 adhesive effect Effects 0.000 claims abstract description 9
- 238000010521 absorption reaction Methods 0.000 claims abstract description 8
- 239000012510 hollow fiber Substances 0.000 claims description 12
- 238000005406 washing Methods 0.000 claims description 10
- 238000007789 sealing Methods 0.000 claims description 9
- 239000008280 blood Substances 0.000 claims description 6
- 210000004369 blood Anatomy 0.000 claims description 6
- 239000004065 semiconductor Substances 0.000 claims description 5
- 229920003002 synthetic resin Polymers 0.000 claims description 4
- 239000000057 synthetic resin Substances 0.000 claims description 4
- 238000011990 functional testing Methods 0.000 claims description 3
- 238000001228 spectrum Methods 0.000 claims description 3
- 239000004826 Synthetic adhesive Substances 0.000 claims description 2
- 239000002245 particle Substances 0.000 claims description 2
- 238000002616 plasmapheresis Methods 0.000 claims 1
- 238000011146 sterile filtration Methods 0.000 claims 1
- 238000000502 dialysis Methods 0.000 abstract description 32
- 239000000853 adhesive Substances 0.000 abstract description 7
- 239000000463 material Substances 0.000 abstract description 6
- 238000013021 overheating Methods 0.000 abstract description 3
- 239000007788 liquid Substances 0.000 description 9
- 238000004519 manufacturing process Methods 0.000 description 8
- 238000010586 diagram Methods 0.000 description 7
- 230000008859 change Effects 0.000 description 5
- 239000012530 fluid Substances 0.000 description 5
- 239000012528 membrane Substances 0.000 description 5
- 238000000926 separation method Methods 0.000 description 5
- 230000008901 benefit Effects 0.000 description 4
- 150000001875 compounds Chemical class 0.000 description 4
- 238000000275 quality assurance Methods 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 3
- 239000000835 fiber Substances 0.000 description 3
- 239000011148 porous material Substances 0.000 description 3
- 238000009826 distribution Methods 0.000 description 2
- 239000003566 sealing material Substances 0.000 description 2
- 235000013361 beverage Nutrition 0.000 description 1
- 238000007664 blowing Methods 0.000 description 1
- 230000000739 chaotic effect Effects 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- -1 fleece Substances 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 239000003365 glass fiber Substances 0.000 description 1
- 238000001631 haemodialysis Methods 0.000 description 1
- 230000000322 hemodialysis Effects 0.000 description 1
- 229940127554 medical product Drugs 0.000 description 1
- 238000001471 micro-filtration Methods 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 230000035699 permeability Effects 0.000 description 1
- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 description 1
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 239000002510 pyrogen Substances 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 239000000565 sealant Substances 0.000 description 1
- 238000004088 simulation Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000008223 sterile water Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000004753 textile Substances 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
- B01D67/0081—After-treatment of organic or inorganic membranes
- B01D67/0095—Drying
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B3/00—Drying solid materials or objects by processes involving the application of heat
- F26B3/32—Drying solid materials or objects by processes involving the application of heat by development of heat within the materials or objects to be dried, e.g. by fermentation or other microbiological action
- F26B3/34—Drying solid materials or objects by processes involving the application of heat by development of heat within the materials or objects to be dried, e.g. by fermentation or other microbiological action by using electrical effects
- F26B3/347—Electromagnetic heating, e.g. induction heating or heating using microwave energy
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F26—DRYING
- F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
- F26B9/00—Machines or apparatus for drying solid materials or objects at rest or with only local agitation; Domestic airing cupboards
- F26B9/06—Machines or apparatus for drying solid materials or objects at rest or with only local agitation; Domestic airing cupboards in stationary drums or chambers
Definitions
- the invention relates to a method for producing filter units containing a plurality of diaphragms or membranes, and a method and a device for drying such filter units after their functional testing.
- Dialysis filter cartridges and their manufacture are known from EP 1 631 152 B1 and DE 102013 006 507 B4.
- the dialysis filter cartridges are required for blood washing. They usually contain a bundle of hollow fibers that provide a fluid path for blood. The space between the outer sides of the hollow fibers and the cartridge housing provides a second liquid path through which the treatment or washing liquid flows. The wall of the hollow fiber separates the fluid paths and allows an osmotic exchange of substances between blood and washing fluid.
- the bundle of hollow fibers is inserted into a housing and the ends of the housing are sealed using synthetic resin or a sealing compound.
- each individual filter cartridge must therefore be individually checked for permeability of the liquid paths and tightness, in accordance with the guidelines for quality assurance of the production processes and environment for medical products.
- the openness of the liquid paths and the tightness of the filter cartridges are tested with sterile water over a specified temperature range.
- the wet dialysis filter cartridge must be dried.
- the filter cartridge is currently dried by blowing warm air through it, optionally supported by microwaves. This step is time-consuming and complex because moisture can collect in places that are less exposed to airflow. In addition, the dipole moment of the water molecules and the high surface tension of water make drying more difficult.
- microwaves The support of drying by microwaves is problematic because the microwave chambers have power-free areas, which is why food is usually heated on a turntable.
- the microwaves are reflected by the walls of the chamber and can penetrate each other wipe out
- the seal of the filter cartridge or the sealing compound must not be damaged by the microwave, for example due to overheating.
- the candle filter usually consists of a filter housing and one or more candles inserted in it, through which the liquid flows from the outside to the inside.
- Closed single-use cartridge filters are common in the pharmaceutical industry, which have to be washed free of pyrogens and tested for leaks after manufacture for quality assurance.
- a typical design of the filter cartridges are wound cartridges, which are wound from a synthetic thread, e.g. from propylene, or a filter medium made from glass fiber, fleece, or a textile material.
- the advantages of such candle filters in a closed filter system are the low risk of contamination and no loss of fluid.
- the individual candle filters also have to be dried again after washing and testing, with the same problems to be overcome as with the dialysis filter cartridges. They are usually vacuum dried, which requires a considerable amount of equipment and time. The alternative use of warm, sterile air is comparatively energy-intensive and very expensive.
- a method for drying closed filter systems especially after a functional test or a Washing comprising providing a chamber having a microwave antenna adapted to receive a filter module, wherein high and low microwave power zones are established in the chamber; providing means for generating microwaves of a discrete frequency in the range of 2.3 to 2.6 GHz in the chamber; the provision of a device which determines the reflected microwave power; the introduction of microwaves of a discrete frequency at which the highest power is converted in the liquid water, hereinafter also referred to as power loss; passing air or gas through the filter module so that evaporated water is removed from the system; and further determining and readjusting the microwave frequency at which the highest power is lost in the water (power dissipation) until the closed filter system is dry.
- the method according to the invention is particularly suitable for closed filter systems and single-use filters which, because of their quality, have to be washed again after manufacture, or have to be checked individually for function and tightness for quality assurance.
- Typical examples of such filter systems are dialysis filters for blood washing or candle filters for the production of particle-free or pyrogen-free pharmaceutical liquids and drugs.
- dialysis filters for blood washing or candle filters for the production of particle-free or pyrogen-free pharmaceutical liquids and drugs.
- the humidity of the gas emerging from the filter module or the filter system is also determined.
- the chamber is also designed in such a way that areas of the filter with a bond or seal are in zones with low microwave power. This serves to protect the bonds from damage
- the means for generating microwaves of a discrete frequency is a semiconductor microwave generator, i.e. a solid-state based microwave generator instead of a magnetron and electron tubes.
- the frequency spectrum from 2.3 to 2.6 GHz is examined to determine at which discrete frequency the absorbed microwave power is greatest—that is, the power converted in the water or the microwave energy introduced in the water hereinafter also referred to as power loss for short.
- This discrete frequency is then used as the starting value for drying. This frequency depends on the size of the filter, with the aforementioned spectrum being valid for filters with approx. 30 cm.
- the filter systems (closed candle filters and dialysis filter cartridges) contain adhesives and sealing materials, it is also important to pay attention to the discrete frequencies at which these materials absorb. Their absorption will usually be outside the range of the different states of the water in and on the fibers of the diaphragm or the filter material, i.e. outside the range of 2.3 to 2.6 GHz, but this should be checked and adjusted if necessary.
- Means for determining the reflected microwave power and the frequency at which the reflected power is lowest or the energy converted in the water is greatest e.g. the S-parameter
- the device for generating microwaves of a discrete frequency is preferably a semiconductor microwave generator. This can preferably also contain a device for determining the converted energy or the reflected power at a discrete frequency.
- the device for drying filters also includes devices for feedback determination and tracking of the frequency to a frequency at which the reflected power is minimal and no other damage to the filter module occurs.
- the device for drying closed filter systems and dialysis filter cartridges is preferably designed in such a way that the chamber is divided into zones with high and low microwave power without contact.
- the chamber is divided into high and low microwave power zones and is also designed so that once the closed filter system or the filter module, the areas with bonding or sealing come to rest in zones with low microwave power.
- the device for drying filter modules and dialysis filter cartridges can also have devices for determining the humidity in the exhaust air or in the exhaust gas. Furthermore, there can preferably be devices which determine the microwave energy absorbed in the chamber and optionally also the scattering parameters for the power input.
- the use of the device is particularly helpful and preferred for dialysis filter cartridges, housings with filter cartridges, and other closed filter systems that are sealed with synthetic resin and/or adhesive.
- the advantage of frequency-guided microwave treatment is that the "free water" in the center of the filter cartridge or filter module is first evaporated with the frequency starting value, then the water bound to the various surfaces is heated and evaporated and finally, via the frequency shift, the water that has accumulated in remote corners and niches of the filter housing.
- the frequency control also changes the wave pattern in the chamber and in a way looks for all free water in the housing or the module.
- the areas with adhesive bonds and seals also contain water, according to the invention these are in areas or zones with lower microwave radiation.
- FIGS. 3 and 4 show the change in the resonant frequency and the effective power introduced as a function of the frequency adjustment for a dialysis filter cartridge, the curves showing the different states of drying.
- Fig. 2 is an illustration of a dialysis filter cartridge and the power introduced by microwaves in the water in the dry filter at resonant frequency, with the mid-range microwave power being absorbed by the wet fibers;
- FIG. 3 shows diagrams (A) of the course of the resonant frequency and (B) of the applied effective power in watts with the frequency adjustment over time;
- FIG. 4 shows a diagram with the time course of the input (absorbed) power in percent and the reflected power in percent together with the percentage of air humidity in the sight glass and the measured air temperature of the outflow in degrees Celsius;
- FIG. 5 is a front view (cutaway) of the microwave chamber: (A) with and (B) without the dialysis filter cartridge inserted, the sealed ends of the cartridge being partially protected from microwave power; (C) rear view of the microwave chamber with connection to the microwave generator, (D) sectional view of the microwave chamber with microwave antenna;
- Fig. 7 shows a diagram of the scattering parameters S1,1 of the chamber (largest version of type A) with an inserted wet dialysis filter cartridge (start of the process) over the frequency band (2.3 - 2.6 GHz) or the frequency band used (2.4 - 2 .5 GHz);
- FIG. 8 shows a diagram of the scattering parameters S 1 ,1 of the chamber of type A with a dry dialysis filter cartridge or at the end of the process;
- FIG. 9 shows a diagram of the scattering parameters S1,1 of the chamber with a wet dialysis filter cartridge of the smallest type B (start of the process) over the frequency band (2.3-2.6 GHz) or the frequency band used;
- FIG. 10 shows a diagram of the scattering parameters S1,1 of the type B chamber with a dry dialysis filter cartridge (at the end of the process);
- FIG. 12 shows the distribution of the power converted in the water in the respective filters of type B (smallest version) at different resonance frequencies;
- Fig. 13 Graphs comparing S-parameters for a type B (smallest design) and type A (largest design) filter.
- a microwave chamber which has a resonant frequency at the lower limit of the relevant frequency band (2.3 to 2.6 GHz) when a closed filter module is used, such as a dialysis filter cartridge or a candle filter when wet.
- the relevant frequency band is between 2.4 and 2.5 GHz, corresponding to medium-sized filter modules with a diameter of 10 to 30 cm.
- correspondingly higher or lower frequency bands are suitable.
- the device and the method are described by way of example for filter systems with a hollow fiber module. However, the device and the method are equally suitable for modules with candle filters and other membrane filters.
- the aforementioned resonant frequency stands for the frequency at which the power reflection of the chamber is minimal and the power consumption takes place in the water; see FIG. 1. It is taken into account that the filters or the filter modules can have different diameters and therefore also contain different amounts of water.
- the chamber is selected in such a way that the largest filter unit, the largest filter module, the largest filter cartridge, which contains the most water and thus has the lowest resonance frequency in the chamber, is still within a usable frequency band of 2.4 GHz - 2.5 GHz , i.e. just above 2.4 GHz
- the resonant frequency of the wet filter is determined by the equipment or the microwave generator, preferably in a scan run, and the determined resonant frequency for drying is taken as the starting value for the microwave.
- This preliminary step can be omitted and is optional if the filter modules are manufactured with very tight tolerances and a constant frequency start value can be used for the microwave generator. Nevertheless, the determination of the starting parameters can represent an optimization of the method.
- the microwave generator begins to deliver power at this frequency into the chamber.
- the use of a warm through-air flow allows drying to take place more quickly, but is not absolutely necessary and very energy-consuming. Sterile warm clean air is very expensive and complex to produce.
- the resonant frequency increases. According to the invention, this change in the resonance is detected by the equipment, for example using the microwave reflection, and the emitted microwave frequency is tracked or increased accordingly.
- the generator follows the change in frequency by adapting the frequency to the absorbed power. This minimizes reflected power and maximizes power input into the water.
- the microwave generator follows the resonant frequency change by adjusting the frequency of the power delivered so that the absorbed power is maximum; see Figure 3. In this way, the reflected power is minimized and the power input into the water is maximized.
- the change in frequency stagnates at a point since most of the water has been discharged (see FIG. 3, after approx. 460 seconds). There is then only water in appreciable amounts in the shielded areas with the sealing material or in the bonding of the filter module (filter cartridge, candle filter, disposable filter)
- the middle image shows that some power couples into the sealing and bonding areas to be protected when the water is pushed out of the middle area.
- this power is not very high due to the low adjustment of less than -1dB, since the microwave generator automatically regulates its output power.
- the power ratio between the central area and the ends differs by more than a factor of 2, so that this is tolerated by the splices, and moisture removal from the splices is also accelerated. through further shielding only a small part of the power reaches this area.
- the use of warm air significantly shortens the final drying step as it drives the remaining water out of the shielded seal very efficiently. The process ends as soon as the measured humidity in the exhaust air falls below a target value; see figure 4.
- the chamber is designed or designed in such a way that the resonance of the chamber when power is input into the water in a type A filter (largest version) when wet is still within the usable frequency band, and that the resonance of the chamber when power is input in the areas to be protected with a type B filter (smallest version) - i.e. in the areas with the adhesive and sealing compound - is outside the usable frequency band when dry.
- the method is specially developed for the drying of filters with a focus on dialysis filters and candle filters. Because of the variable microwave frequency emitted, the process requires that the microwaves be generated by semiconductors or solid-state technology. Magnetrons can only generate and emit microwaves of a fixed specific frequency or a chaotic frequency. A controllable drying process can be achieved according to the invention through the use of solid-state microwave generators, which allow a very precise setting of power and frequency. The entire drying process can be achieved entirely by microwaves without additional drying by hot air. Power adjustment is not possible with conventional magnetron-based microwave technology.
- the drying application can have a modular structure, so that the application is scalable in parallel and individually adaptable.
- the filter modules dialysis filter and candle filter cartridges
- the filter modules can be inserted into the drying chambers manually or fully automatically using a robot, as is currently the case.
- a microwave chamber with non-contact separation of the zones corresponding to the functionally different areas of the filter cartridges and modules is presented.
- the drying chamber offers the advantage that it can be equipped with filter cartridges to be dried via a door.
- the person skilled in the art recognizes that the assembly can be carried out from the front, from behind, from the side or also from above or below.
- a chamber which allows the use of robots for equipping the drying chamber is preferred.
- the separation of the zones corresponds to the areas with high and low power absorption.
- the chamber requires a connection for discharging the water.
- the power introduced by the microwave generator and converted in the water occurs primarily in the central area of the filter, where most of the water is present. Due to the design and the non-contact separation of the zones, protective caps for the areas to be protected on the filter modules are no longer required. This increases the reproducibility of drying and makes the drying process considerably easier. Microwave drying is made even safer by the fact that the resonances with losses in the zones to be protected are outside the ISM band. Furthermore, the fact that the resonance of the chamber changes due to the loss of water is used. This fact, and by measuring and tracking the resonance, one can introduce microwave power into the water at low reflection.
- the water is also bound differently in the filter material or on the fibers of a dialysis filter cartridge: as "free" water or absorbed on a surface. These different states cause different resonance frequencies or peaks in the curve with the resonance frequency.
- a gas preferably compressed air, to discharge the evaporated water accelerates the drying process. This actively dries the microwave-sensitive areas with sealing and adhesive mass.
- a device for drying closed filter systems with a hollow fiber or candle filter module comprising a microwave chamber that can be equipped with a filter cartridge or a filter module.
- the microwave chamber distinguishes itself by dividing zones of high and low microwave absorption without contact.
- the zone with high absorbed power corresponds to the central area of the filter module, where the bundle of hollow fibers or the filter material is located.
- the zones with low microwave absorption correspond to the end areas of the filter cartridge, which are more sensitive to microwaves, where there are further seals and adhesives.
- the microwave frequency with the highest absorbed power is first determined, then microwave power is introduced at this frequency, and while the filter module is drying, the reflected microwave power is continuously determined by the equipment and kept as low as possible by tracking the microwave frequency.
- the water is also discharged from the filter with a stream of air or gas.
- the process requires a generator whose frequency can be adjusted - in practice a microwave generator on solid state technology. It then allows quick and gentle drying. In particular, rejects due to accidental overheating of temperature-sensitive areas of the filter system and at the seals and bonds are avoided.
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- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Electromagnetism (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Manufacturing & Machinery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- External Artificial Organs (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP21770123.4A EP4196250A1 (de) | 2020-08-12 | 2021-08-12 | Trocknung von filtermodulen und filtergehäusen mit einem frequenzgeführten mikrowellenprozess |
DE112021004239.4T DE112021004239A5 (de) | 2020-08-12 | 2021-08-12 | Trocknung von filtermodulen und filtergehäusen mit einem frequenzgeführten mikrowellenprozess |
US18/020,668 US20240035747A1 (en) | 2020-08-12 | 2021-08-12 | Drying of filter modules and filter housings using a frequency-guided microwave process |
CN202180069708.0A CN116472433A (zh) | 2020-08-12 | 2021-08-12 | 用频率引导的微波工艺干燥过滤模块和过滤外壳 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102020121262 | 2020-08-12 | ||
DE102020121262.3 | 2020-08-12 |
Publications (1)
Publication Number | Publication Date |
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WO2022033637A1 true WO2022033637A1 (de) | 2022-02-17 |
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ID=77774644
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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PCT/DE2021/100693 WO2022033637A1 (de) | 2020-08-12 | 2021-08-12 | Trocknung von filtermodulen und filtergehäusen mit einem frequenzgeführten mikrowellenprozess |
Country Status (5)
Country | Link |
---|---|
US (1) | US20240035747A1 (de) |
EP (1) | EP4196250A1 (de) |
CN (1) | CN116472433A (de) |
DE (2) | DE112021004239A5 (de) |
WO (1) | WO2022033637A1 (de) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE102022124044A1 (de) | 2022-09-20 | 2024-03-21 | Püschner GmbH & Co. Kommanditgesellschaft | Verfahren und Vorrichtung zur Vakuumtrocknung von Produkten, insbesondere Membranfiltern, wie zum Beispiel Dialysatoren, insbesondere nach einem Waschen oder einer Funktionsprüfung, mittels Mikrowellenenergie |
Citations (13)
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JPH04371219A (ja) | 1991-06-20 | 1992-12-24 | Tsukishima Kikai Co Ltd | 中空糸の集束方法 |
US5556591A (en) | 1992-01-21 | 1996-09-17 | Millipore S.A. | Membrane sealing techniques using thermoplastic polymers |
DE29802402U1 (de) * | 1998-02-12 | 1998-05-14 | Saxonia Medical Gmbh | Vorrichtung zum Trocknen von Membranmodulen |
JP2003284931A (ja) * | 2002-03-27 | 2003-10-07 | Asahi Medical Co Ltd | 中空糸膜の乾燥装置 |
DE10333639B3 (de) * | 2003-07-24 | 2004-07-15 | Püschner Gmbh & Co. Kg | Verfahren und Anlage zum Trocknen von Membranmodulen, insbesondere Dialysatoren, mit mindestens zwei Flüssigkeitsanschlüssen mittels Mikrowellenenergie |
JP2006167597A (ja) * | 2004-12-15 | 2006-06-29 | Toyobo Co Ltd | 中空糸膜束の乾燥方法 |
EP1733784A1 (de) * | 2004-03-23 | 2006-12-20 | Toyo Boseki Kabushiki Kaisha | Bündel von permselektiven hohlfasermembranen auf polysulfonbasis und herstellungsverfahren dafür |
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EP1631152B1 (de) | 2003-03-20 | 2010-03-10 | NxStage Medical, Inc. | Vorrichtung und verfahren zur herstellung von filtern |
US20120234745A1 (en) | 2011-03-16 | 2012-09-20 | Markel Corporation | Fluoropolymer hollow fiber membrane with fluoro-copolymer and fluoro-terpolymer bonded end portion(s) and method to fabricate |
DE102013006507B4 (de) | 2013-04-16 | 2015-06-03 | Flg Automation Ag | Vorrichtung und Verfahren zum Herstellen einer Dialyse-Filterpatrone |
DE102018115827A1 (de) * | 2018-06-29 | 2020-01-02 | Gerlach Maschinenbau Gmbh | Vorrichtung zum Vernetzen mit geregelten Mikrowellen |
DE102020105340B3 (de) | 2020-02-28 | 2021-04-08 | Zahoransky Automation & Molds GmbH | Vorrichtung und Verfahren zum Trocknen von Dialysefiltern |
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2021
- 2021-08-12 US US18/020,668 patent/US20240035747A1/en active Pending
- 2021-08-12 EP EP21770123.4A patent/EP4196250A1/de active Pending
- 2021-08-12 DE DE112021004239.4T patent/DE112021004239A5/de active Pending
- 2021-08-12 CN CN202180069708.0A patent/CN116472433A/zh active Pending
- 2021-08-12 WO PCT/DE2021/100693 patent/WO2022033637A1/de active Application Filing
- 2021-08-12 DE DE102021121051.8A patent/DE102021121051A1/de active Pending
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JPH04371219A (ja) | 1991-06-20 | 1992-12-24 | Tsukishima Kikai Co Ltd | 中空糸の集束方法 |
US5556591A (en) | 1992-01-21 | 1996-09-17 | Millipore S.A. | Membrane sealing techniques using thermoplastic polymers |
DE29802402U1 (de) * | 1998-02-12 | 1998-05-14 | Saxonia Medical Gmbh | Vorrichtung zum Trocknen von Membranmodulen |
JP2003284931A (ja) * | 2002-03-27 | 2003-10-07 | Asahi Medical Co Ltd | 中空糸膜の乾燥装置 |
EP1631152B1 (de) | 2003-03-20 | 2010-03-10 | NxStage Medical, Inc. | Vorrichtung und verfahren zur herstellung von filtern |
DE10333639B3 (de) * | 2003-07-24 | 2004-07-15 | Püschner Gmbh & Co. Kg | Verfahren und Anlage zum Trocknen von Membranmodulen, insbesondere Dialysatoren, mit mindestens zwei Flüssigkeitsanschlüssen mittels Mikrowellenenergie |
EP1733784A1 (de) * | 2004-03-23 | 2006-12-20 | Toyo Boseki Kabushiki Kaisha | Bündel von permselektiven hohlfasermembranen auf polysulfonbasis und herstellungsverfahren dafür |
JP2006167597A (ja) * | 2004-12-15 | 2006-06-29 | Toyobo Co Ltd | 中空糸膜束の乾燥方法 |
DE102007035583A1 (de) | 2006-07-28 | 2008-04-17 | E.I. Du Pont De Nemours And Company, Wilmington | Materialien mit auf einem Ende stehenden Fasern |
US20120234745A1 (en) | 2011-03-16 | 2012-09-20 | Markel Corporation | Fluoropolymer hollow fiber membrane with fluoro-copolymer and fluoro-terpolymer bonded end portion(s) and method to fabricate |
DE102013006507B4 (de) | 2013-04-16 | 2015-06-03 | Flg Automation Ag | Vorrichtung und Verfahren zum Herstellen einer Dialyse-Filterpatrone |
DE102018115827A1 (de) * | 2018-06-29 | 2020-01-02 | Gerlach Maschinenbau Gmbh | Vorrichtung zum Vernetzen mit geregelten Mikrowellen |
DE102020105340B3 (de) | 2020-02-28 | 2021-04-08 | Zahoransky Automation & Molds GmbH | Vorrichtung und Verfahren zum Trocknen von Dialysefiltern |
WO2021170726A1 (de) * | 2020-02-28 | 2021-09-02 | Zahoransky Automation & Molds GmbH | Vorrichtung und verfahren zum trocknen von dialysefiltern |
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DE102021121051A1 (de) | 2022-02-17 |
DE112021004239A5 (de) | 2023-08-10 |
CN116472433A (zh) | 2023-07-21 |
EP4196250A1 (de) | 2023-06-21 |
US20240035747A1 (en) | 2024-02-01 |
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