WO2021191353A3 - Verfahren zur bereitstellung eines vakzins gegen coronaviren - Google Patents

Verfahren zur bereitstellung eines vakzins gegen coronaviren Download PDF

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Publication number
WO2021191353A3
WO2021191353A3 PCT/EP2021/057746 EP2021057746W WO2021191353A3 WO 2021191353 A3 WO2021191353 A3 WO 2021191353A3 EP 2021057746 W EP2021057746 W EP 2021057746W WO 2021191353 A3 WO2021191353 A3 WO 2021191353A3
Authority
WO
WIPO (PCT)
Prior art keywords
virus
methods
providing
vaccine against
vaccine
Prior art date
Application number
PCT/EP2021/057746
Other languages
English (en)
French (fr)
Other versions
WO2021191353A2 (de
Inventor
Wolfgang Würfel
Franziska WÜRFEL
Original Assignee
Wuerfel Wolfgang
Wuerfel Franziska
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wuerfel Wolfgang, Wuerfel Franziska filed Critical Wuerfel Wolfgang
Priority to CN202180024625.XA priority Critical patent/CN115443149A/zh
Priority to JP2022558141A priority patent/JP2023518886A/ja
Priority to EP21715228.9A priority patent/EP4126024A2/de
Publication of WO2021191353A2 publication Critical patent/WO2021191353A2/de
Publication of WO2021191353A3 publication Critical patent/WO2021191353A3/de

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
    • C12N2770/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
    • C12N2770/20061—Methods of inactivation or attenuation

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Virology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Verfahren zur Bereitstellung eines Vakzins zur Immunisierung eines Individuums gegen eine durch einen Virus der Familie der Coronaviren verursachte Erkrankung sind offenbart. Das Verfahren umfasst ein Erhalten einer Probe des Virus; ein Inaktivieren des Virus, indem Nukleinsäuren mit genetischer Information des Virus zerstört oder entfernt werden; und ein Aufbereiten des inaktivierten Virus um ein darreichungsfähiges Vakzin zur Darreichung als inhalationsfähiges Aerosol oder als gurgelfähige Lösung zu erhalten. Dergestalt bereitgestellte Vakzine sowie deren Verwendung sind ebenfalls offenbart.
PCT/EP2021/057746 2020-03-26 2021-03-25 Verfahren zur bereitstellung eines vakzins WO2021191353A2 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CN202180024625.XA CN115443149A (zh) 2020-03-26 2021-03-25 用于提供抗冠状病毒的疫苗的方法
JP2022558141A JP2023518886A (ja) 2020-03-26 2021-03-25 ワクチン提供方法
EP21715228.9A EP4126024A2 (de) 2020-03-26 2021-03-25 Verfahren zur bereitstellung eines vakzins gegen coronaviren

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102020108453.6 2020-03-26
DE102020108453.6A DE102020108453A1 (de) 2020-03-26 2020-03-26 Verfahren zur Bereitstellung eines Vakzins

Publications (2)

Publication Number Publication Date
WO2021191353A2 WO2021191353A2 (de) 2021-09-30
WO2021191353A3 true WO2021191353A3 (de) 2022-09-01

Family

ID=75278035

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2021/057746 WO2021191353A2 (de) 2020-03-26 2021-03-25 Verfahren zur bereitstellung eines vakzins

Country Status (5)

Country Link
EP (1) EP4126024A2 (de)
JP (1) JP2023518886A (de)
CN (1) CN115443149A (de)
DE (1) DE102020108453A1 (de)
WO (1) WO2021191353A2 (de)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016130569A1 (en) * 2015-02-09 2016-08-18 Mj Biologics, Inc. A composition comprising pedv antigens and methods for making and using the composition

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016130569A1 (en) * 2015-02-09 2016-08-18 Mj Biologics, Inc. A composition comprising pedv antigens and methods for making and using the composition

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
LI YEN-DER ET AL: "Coronavirus vaccine development: from SARS and MERS to COVID-19", JOURNAL OF BIOMEDICAL SCIENCE, 20 December 2020 (2020-12-20), pages 1 - 23, XP055819408, Retrieved from the Internet <URL:https://jbiomedsci.biomedcentral.com/track/pdf/10.1186/s12929-020-00695-2.pdf> [retrieved on 20210629], DOI: 10.1186/s12929-020-00695-2 *
LIN JIANG-TAO ET AL: "Safety and immunogenicity from a phase I trial of inactivated severe acute respiratory syndrome coronavirus vaccine", ANTIVIR. THER., vol. 12, no. 7, 1 January 2007 (2007-01-01), pages 1107 - 1113, XP055819262, Retrieved from the Internet <URL:http://www.ncbi.nlm.nih.gov/pubmed/18018769> *
QU D ET AL: "Intranasal immunization with inactivated SARS-CoV (SARS-associated coronavirus) induced local and serum antibodies in mice", VACCINE, ELSEVIER, AMSTERDAM, NL, vol. 23, no. 7, 4 January 2005 (2005-01-04), pages 924 - 931, XP027651769, ISSN: 0264-410X, [retrieved on 20050104] *
WU FAN ET AL: "A new coronavirus associated with human respiratory disease in China", NATURE, MACMILLAN JOURNALS LTD., ETC, LONDON, vol. 579, no. 7798, 3 February 2020 (2020-02-03), pages 265 - 269, XP037099569, ISSN: 0028-0836, [retrieved on 20200203], DOI: 10.1038/S41586-020-2008-3 *

Also Published As

Publication number Publication date
CN115443149A (zh) 2022-12-06
WO2021191353A2 (de) 2021-09-30
EP4126024A2 (de) 2023-02-08
DE102020108453A1 (de) 2021-09-30
JP2023518886A (ja) 2023-05-08

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