WO2021121155A1 - 一种新型试剂添加系统 - Google Patents
一种新型试剂添加系统 Download PDFInfo
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- WO2021121155A1 WO2021121155A1 PCT/CN2020/135703 CN2020135703W WO2021121155A1 WO 2021121155 A1 WO2021121155 A1 WO 2021121155A1 CN 2020135703 W CN2020135703 W CN 2020135703W WO 2021121155 A1 WO2021121155 A1 WO 2021121155A1
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- reagent
- way valve
- novel
- liquid outlet
- main pipeline
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
Definitions
- the invention relates to a laboratory appliance, in particular to a novel reagent addition system.
- reagents are often used in laboratories during experiments, and the reagents are generally contained in a kit.
- the tester needs to remove the reagent from the kit, the usual practice is to open the lid of the kit, and then use a syringe or dropper to suck a certain amount of reagent, take it out and add it to the sample to be tested. It is inevitable that some excess reagents will be put back into the kit during the operation. If the test personnel are unskilled or careless, they can easily contaminate their hands, bodies or test equipment. If the reagents used are corrosive or toxic, the consequences will be serious.
- the technical problem to be solved by the present invention is to provide a new reagent addition system, which is used to solve the problem of manual addition of reagents in existing tests.
- the technical solution adopted by the present invention is: a new type of reagent addition system, which includes a compressor and a reagent unit, the reagent unit includes a new type of reagent box, a main pipeline is provided between the compressor and the reagent unit, and the compressor The device delivers compressed gas to the reagent unit through the main pipeline.
- the new type kit includes a box body and a cylindrical liquid outlet tube fixed at the bottom of the liquid outlet tube.
- the lower part of the inner wall of the liquid outlet tube is provided with a circular sealing gasket fixedly connected to it, and the sealing gasket is provided with A circular liquid outlet perpendicular to the center of the liquid outlet
- the top of the liquid outlet is provided with a ball that can slide on the inner wall of the outlet pipe
- the upper part of the ball is fixed with a magnetic rod that can slide on the inner wall of the outlet pipe.
- An electromagnetic coil fixedly connected to the liquid outlet pipe is arranged on the outer upper side, and the top of the box body is provided with an air inlet fixedly connected to the inside and outside of the box body, and the air inlet is connected with the main pipe.
- a spherical recess is provided in the center of the top of the sealing gasket, and the bottom of the spherical recess communicates with the liquid outlet, and the ball is compressed in the spherical recess by the magnetic rod.
- the bottom of the liquid outlet pipe is provided with a ring magnet fixedly connected to it.
- the reagent unit further includes a gas valve provided between the new-type reagent box and the main pipeline.
- a branch pipe is arranged between the novel reagent kit and the gas distribution valve.
- the gas distribution valve is a three-way valve.
- the reagent unit includes a plurality of reagent units connected in sequence, an extension pipe is arranged between two adjacent reagent units, and two ends of the extension pipe are respectively connected with adjacent gas distribution valves.
- a one-way valve is provided on the branch pipe.
- a one-way valve is provided on the main pipeline.
- the positive effect of the present invention is that the new reagent addition system can quantitatively add multiple reagents to the test process at the same time, without manually opening the kit to take out the reagents and then performing the test, thereby avoiding various drawbacks of manual operation and improving the test or inspection performance. effectiveness.
- the opening and closing actions of the liquid outlet device of the new reagent kit can be realized by the electric control system controlling the power on and off of the solenoid coil, so that there is no need to manually open the reagent kit to take out the reagent and use it for the test operation.
- the present invention can also provide reagents quantitatively, which can be realized by controlling the electrification time of the electromagnetic coil by the electronic control system according to the type of the reagent and the air pressure inside the novel reagent box and other parameters. Therefore, the new kit can also meet the requirements of the automatic test system.
- Figure 1 is a schematic diagram of the structure of the present invention.
- Figure 2 is a schematic diagram of the three-way valve of the present invention with one inlet and two outlets.
- Fig. 3 is a schematic diagram of the structure of the three-way valve of the present invention with upper inlet and lower outlet.
- Figure 4 is a schematic diagram of the structure of the three-way valve of the present invention with the upper inlet and the left outlet.
- Fig. 5 is a structural schematic diagram of the three-way valve of the present invention in a cut-off state.
- Figure 6 is a schematic diagram of the structure of the novel kit.
- Fig. 7 is a schematic diagram of the structure of the liquid outlet pipe.
- the new reagent addition system includes a compressor 1, a main pipe 8, a one-way valve 6 installed on the main pipe 8, and a number of reagent units connected in sequence.
- the reagent unit includes a three-way valve 3 and a new type reagent box 5 connected with the three-way valve 3 through a branch pipe 7, and the branch pipe 7 is provided with a one-way valve 6.
- the compressor 1 is connected to one end of the main pipe 8, the other end of the main pipe 8 is connected to the three-way valve 3 in the first reagent unit, and the two ends of the branch pipe 7 are respectively connected to the three-way valve 3 and the new reagent Box 5 is connected.
- An extension pipe 4 is arranged between the three-way valves 3 of adjacent gas distribution units.
- the new type reagent box 5 is a closed container containing reagents, and the reagents inside can be quantitatively discharged by compressed gas.
- the compressed gas provided by the air compressor 1 is filtered, dried, and then delivered to the novel reagent box 5 after passing through the main pipeline 8, the three-way valve 3 and the branch pipe 7, so as to ensure the normal operation of the novel reagent box 5.
- Adjacent three-way valves 3 can be directly connected through a quick connector 2, and the distance between them can also be connected through an extension pipe 4 if it is necessary to increase the distance between them. Therefore, during the test, it is only necessary to connect the reagent units used directly or through the extension tube 4 in sequence.
- the quick connector 2 is divided into two parts, which are respectively installed on the parts that need to be docked, and these parts can be assembled and disassembled conveniently and quickly through the quick connector 2.
- the three-way valve 3 mainly includes a valve core 32 and a valve body 31.
- the valve core 32 is a sphere, and the contact surface of the sphere and the valve body 31 is a sealing surface. There is a T-shaped hole inside the sphere.
- the valve core 32 can rotate inside the valve body 31. Every time the valve core 31 rotates 90 degrees, the three-way valve 3 changes to a working state.
- the three-way valve 3 has four working states.
- Figures 2 to 5 show the working state of the spool 31 rotated 90 degrees counterclockwise. The direction of the arrow is the direction in which the gas passing through the current three-way valve 3 can flow, and the arrow with an X sign indicates that this direction is currently in the cut-off state. .
- Figure 2 Upward entry, downward and leftward exit.
- Figure 3 Three-way valve cut-off.
- Figure 4 Top in and bottom out.
- Figure 5 Top in and left out.
- the on and off of the gas source of each reagent unit can be conveniently controlled, and the compressed gas can be easily distributed to each reagent unit, which provides convenience for the combination and separation of the reagent units.
- the one-way valve 6 on the branch pipe 7 can prevent the compressed gas in the novel reagent box 5 from being ejected through the branch pipe 7 and accidents occur.
- the one-way valve 6 on the main pipeline 8 can prevent the compressed gas behind the one-way valve 6 from flowing back after the compressor 1 stops operating or fails.
- the novel reagent kit 5 includes a closed box body 56, an air inlet 57 at the top of the box body 56 and a liquid outlet tube 58 at the bottom of the box body 56.
- the air inlet 57 and the three-way valve 3 are connected by a branch pipe 7.
- the box body 56, the liquid outlet tube 58 and the air inlet 57 are all made of high-strength plastic or stainless steel.
- the liquid outlet tube 58 is cylindrical, and the lower part of its inner wall is provided with a circular rubber seal fixedly connected to it.
- a gasket 59 the center of the gasket 59 is provided with a circular liquid outlet 51 that vertically penetrates its upper and lower surfaces, and the top of the liquid outlet 51 is provided with a steel ball 53 whose diameter is larger than that of the liquid
- the diameter of the opening 51, the upper part of the ball 53 is provided with a magnetic rod 54 fixedly connected to it, and the ball 53 and the magnetic rod 54 can slide freely up and down inside the liquid outlet tube 58.
- the top center of the sealing gasket 59 is provided with a spherical recess, and the bottom of the recess communicates with the liquid outlet 51.
- An electromagnetic coil 55 fixedly connected to the liquid outlet tube 58 is provided on the outer upper side thereof.
- the bottom of the liquid outlet pipe 58 is provided with an annular magnet 52 fixedly connected to it.
- the box body 56 contains reagents for experiments, and the air inlet 57 connects the inside of the box body 56 with an external air source, so that the inside of the box body 56 can maintain a certain air pressure.
- the ball 53 and the magnetic rod 54 fixedly connected to it can reliably hold the liquid outlet 51 under the action of gravity, the attraction of the ring magnet 52 and the pressure of the liquid inside the box 56 Blocking; when the electromagnetic coil 55 is energized, it produces an electromagnetic attraction force on the magnetic rod 54 and the ball 53, which is greater than the gravity acting on the magnetic rod 54 and the ball 53, and the ring magnet 52
- the electromagnetic coil 55 when the electromagnetic coil 55 is energized, it produces an electromagnetic attraction force on the magnetic rod 54 and the ball 53, which is greater than the gravity acting on the magnetic rod 54 and the ball 53, and the ring magnet 52
- the sum of the attraction force and the pressure inside the box body 56 therefore the magnetic rod and the ball 53 will slide upward along the inner wall of the liquid outlet tube 58 under the electromagnetic attraction force of the electromagnetic coil 55, so that the ball 53 and the liquid outlet 51 is separated, and the reagent inside the box body 56 will be discharged through the liquid outlet 51.
- the size of the hole in the center of the gasket 59 and the inner hole of the liquid outlet 58 are also the same. It is a fixed value, so the amount of reagent flowing out of the box body 56 per unit time is related to the air pressure inside the box body 56 and the viscosity of the reagent. Therefore, when the air pressure inside the box body 56 and the viscosity of the reagent are known, the release amount of the reagent inside the box body 56 can be controlled by controlling the power-on time of the electromagnetic coil 55. Therefore, the new type reagent box 5 is more suitable for an automatic test system.
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Abstract
一种新型试剂添加系统，包括压气装置(1)、主管道(8)、安装在主管道(8)上的单向阀(6)和若干试剂单元。试剂单元包括三通阀(3)、连接三通阀(3)和新型试剂盒(5)的支管(7)，安装在支管(7)上的单向阀(6)和新型试剂盒(5)。压气装置(1)和第一个试剂单元中的三通阀(3)通过主管道(8)连接，三通阀(3)和新型试剂盒(5)通过支管(7)连接。相邻的两个配气单元之间中的三通阀(3)由延长管(4)连接。主管道(8)和三通阀(3)、三通阀(3)和支管(7)、支管(7)和新型试剂盒(5)、三通阀(3)之间和延长管(4)之间均有快速接头(2)。该新型试剂添加系统无需人工打开试剂盒取出试剂再进行试验，从而避免了人工操作的各种弊端，并可提高试验或检验的效率。
Description
本发明涉及一种实验室用具，特别涉及一种新型试剂添加系统。
实验室在试验时经常用到各种试剂，试剂一般装在试剂盒内。当在试验人员需要从试剂盒中取出试剂时，通常的做法是需要试验人员打开试剂盒的盖子，然后使用注射器或滴管吸取一定量的试剂，将其取出后再添加到待测试样品中。在操作中难免会有一些多余的试剂被重新放回试剂盒。试验人员如果操作不熟练或不注意还容易污染到手上、身上或试验设备上。如果所使用的试剂具有一定的腐蚀性或毒性，后果就会很严重。
本发明所要解决的技术问题是提供一种新型试剂添加系统，用于解决现有试验中需要人工添加试剂的问题。
本发明所采用的技术方案是：一种新型试剂添加系统，其包括压气装置和试剂单元，所述试剂单元包括新型试剂盒，所述压气装置与试剂单元之间设有主管道，所述压气装置通过主管道将压缩气体输送到试剂单元。
进一步的，所述新型试剂盒包括盒体和固定在其底部的圆筒形的出液管，所述出液管内壁下部设有与其固定连接的圆形的密封垫，所述密封垫设有垂直贯穿其中心的圆形的出液口，所述出液口顶部设有可在出液管内壁滑动的圆珠，所述圆珠上部固定有可在出液管内壁滑动的磁棒，所述出液管外部上侧设有与其固定连接的电磁线圈，所述盒体顶部设有与其固定连接的可连通其内部和外部的进气口，所述进气口与主管道相连。
进一步的，所述密封垫顶部中心设有球形的凹坑，所述球形凹坑底部与出液口相通，所述圆珠被磁棒压紧在球形凹坑内。
进一步的，所述出液管底部设有与其固定连接的环形磁铁。
进一步的，所述试剂单元还包括设在新型试剂盒和主管道之间的配气阀。
进一步的，所述新型试剂盒和配气阀之间设有支管。
进一步的，所述配气阀为三通阀。
进一步的，所述试剂单元包括依次相连的若干个，相邻两个试剂单元之间设有延长管，所述延长管两端分别与相邻的配气阀连接。
进一步的，所述支管上设有单向阀。
进一步的，所述主管道上设有单向阀。
本发明的积极效果为：新型试剂添加系统可同时为试验过程定量添加多种试剂，无需人工打开试剂盒取出试剂再进行试验，从而避免了人工操作的各种弊端，并可提高试验或检验的效率。新型试剂盒的出液装置打开和关闭动作可以由电控系统控制电磁线圈的得电与失电来实现，从而无需人工打开试剂盒取出试剂再用于试验操作。本发明也可定量提供试剂，可由电控系统根据试剂的类型和新型试剂盒内部的气压等参数通过控制电磁线圈的得电时间来实现。因而本新型试剂盒也可满足自动测试系统的要求。
图1是本发明的结构示意图。
图2是本发明三通阀一进二出的结构示意图。
图3是本发明三通阀上进下出的结构示意图。
图4是本发明三通阀上进左出的结构示意图。
图5是本发明三通阀截止状态的结构示意图。
图6是新型试剂盒的结构示意图。
图7是出液管部位的结构示意图。
图中，1、压气装置；2、快速接头；3、三通阀；4、延长管；5、新型试剂盒；6、单向阀；7、支管；8、主管道；32、阀芯；31、阀体；51、出液口；52、环形磁铁；53、圆珠；54、磁棒；55、电磁线圈；56、盒体；57、进气口；58、出液管；59、密封垫。
如附图1所示，新型试剂添加系统包括压气装置1、主管道8、安装在主管道8上的单向阀6和若干个依次顺序连接的试剂单元。所述试剂单元包括三通阀3和与三通阀3通过支管7连接的新型试剂盒5，所述支管7上设有单向阀6。所述压气装置1与主管道8一端连接，所述主管道8的另一端和第一个试剂单元中的三通阀3连接，所述支管7的两端分别与三通阀3和新型试剂盒5相连。相邻配气单元的三通阀3之间设有延长管4，所述新型试剂盒5为密闭的容器，其内装有试剂，可由压缩气体将其内部的试剂定量排出。主管道8和三通阀3、三通阀3和支管7、支管7和新型试剂盒5、三通阀3和延长管4之间均设有快速接头2。所述压气装置1提供的压缩气体经过过滤、干燥后经过主管道8、三通阀3和支管7后输送到新型试剂盒5，以保障新型试剂盒5的正常工作。
相邻的三通阀3可通过快速接头2直接相连，如需要加长它们之间的距离也可通过延长管4连接。因此，在试验时，只须将所使用的试剂单元依次直接相连或或通过延长管4连接即可。快速接头2分为两部分，分别安装在所需对接的部件上，通过快速接头2可以将这些部件方便快速的组装和拆卸。
如图1至5所示，所述三通阀3主要包括阀芯32和阀体31两部分，所述阀芯32为球体，所述球体和阀体31接触的表面为密封面，所述球体内部有T形孔。所述阀芯32可在阀体31内部旋转。所述阀芯31每旋转90度时，三通阀3即更换一种工作状态。所述三通阀3共有四种工作状态。图2至图5为阀芯31沿逆时针间隔90度旋转后的工作状态，箭头方向为通过当前三通阀3的气体可流动的方向，箭头上带X号的表示当前此方向为截止状态。
三通阀3的四种工作状态如下：图2：上进，下和左出。图3：三通阀截止。图4：上进下出。图5：上进左出。
通过三通阀3的各个状态可很方便的控制各个试剂单元气源的开和关，可很方便的将压缩气体分配到各个试剂单元，为试剂单元的组合和拆分提供方便。
当所述支管7和三通阀3之间的快速接头被拆开时，所述支管7上的单向阀6可阻止新型试剂盒5内的压缩气体通过支管7喷出而发生意外。所述主管道8上的单向阀6可防止在压气装置1停止运行或发生故障后导致单向阀6后的压缩气体回流。
如图6和图7所示，所述新型试剂盒5包括密闭的盒体56，所述的盒体56顶部的进气口57和盒体56底部的出液管58，所述进气口57和三通阀3通过支管7连接。所述盒体56、出液管58和进气口57均采用高强度塑料或不锈钢制作，所述的出液管58为圆筒形，其内壁下部设有与其固定连接的圆形的橡胶密封垫59，所述密封垫59中心设有垂直贯穿其上下表面的圆形的出液口51，所述出液口51顶部设有钢质的圆珠53，所述圆珠53直径大于出液口51直径，所述圆珠53上部设有与其固定连接的磁棒54，所述的圆珠53和磁棒54可在出液管58内部上下自由滑动。所述的密封垫59顶部中心设有球形的凹坑，该凹坑底部与出液口51相通。所述出液管58外部上侧设有与其固定连接的电磁线圈55。所述的出液管58底部设有与其固定连接的环形磁铁52。所述盒体56内部装有用于实验的试剂，所述进气口57将盒体56内部和外接气源连通，可使盒体56内部保持一定的气压。当所述电磁线圈55失电后，所述的圆珠53和与其固定连接的磁棒54在重力、环形磁铁52的吸引以及盒体56内部液体的压力作用下可将出液口51可靠的封堵；当所述电磁线圈55得电后，其对磁棒54和圆珠53产生电磁吸引力，所述电磁吸引力大于作用在磁棒54和圆珠53上的重力、环形磁铁52的吸引力和盒体56内部的压力之和，因此所述磁棒和圆珠53会在电磁线圈55的电磁吸引力作用下沿出液管58内壁向上滑动，从而使圆珠53和出液口51分离，所述盒体56内部的试剂会通过出液口51排出。
由于所述出液管58与磁棒54，圆珠53与出液管58之间的间隙为均为固定值，所述密封垫59中心的孔和出液口58内部的各孔尺寸也均为固定值，因此单位时间内从所述盒体56内部流出的试剂的量与盒体56内部气压和试剂的黏度有关。因此，在已知盒体56内部气压和试剂的黏度时，可通过控制电磁线圈55的得电时间来控制盒体56内部试剂的释放量，因而此新型试剂盒5更加适合自动测试系统。
Claims (10)
- 一种新型试剂添加系统，其特征在于，其包括压气装置（1）和试剂单元，所述试剂单元包括新型试剂盒（5），所述压气装置（1）与试剂单元之间设有主管道（8），所述压气装置（1）通过主管道（8）将压缩气体输送到试剂单元。
- 根据权利要求1所述新型试剂添加系统，其特征在于，所述新型试剂盒（5）包括盒体（56）和固定在其底部的圆筒形的出液管（58），所述出液管（58）内壁下部设有与其固定连接的圆形的密封垫（59），所述密封垫（59）设有垂直贯穿其中心的圆形的出液口（51），所述出液口（51）顶部设有可在出液管（58）内壁滑动的圆珠（53），所述圆珠（53）上部固定有可在出液管（58）内壁滑动的磁棒（54），所述出液管（58）外部上侧设有与其固定连接的电磁线圈（55），所述盒体（56）顶部设有与其固定连接的用于连通其内部和外部的进气口（57），所述进气口（57）与主管道（8）相连。
- 根据权利要求2所述新型试剂添加系统，其特征在于，所述密封垫（59）顶部中心设有球形的凹坑，所述球形凹坑底部与出液口（51）相通，所述圆珠（53）被磁棒（54）压紧在球形凹坑内。
- 根据权利要求2所述新型试剂添加系统，其特征在于，所述出液管（58）底部设有与其固定连接的环形磁铁（52）。
- 根据权利要求1所述新型试剂添加系统，其特征在于，所述试剂单元还包括设在新型试剂盒（5）和主管道（8）之间的配气阀。
- 根据权利要求5所述新型试剂添加系统，其特征在于，所述新型试剂盒（5）和配气阀之间设有支管（7）。
- 根据权利要求5所述新型试剂添加系统，其特征在于，所述配气阀为三通阀（3）。
- 根据权利要求5所述新型试剂添加系统，其特征在于，所述试剂单元包括依次相连的若干个，相邻两个试剂单元之间设有延长管（4），所述延长管（4）两端分别与相邻的配气阀连接。
- 根据权利要求6所述新型试剂添加系统，其特征在于，所述支管（7）上设有单向阀（6）。
- 根据权利要求1所述新型试剂添加系统，其特征在于，所述主管道（8）上设有单向阀（6）。
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| CN111175528A (zh) * | 2019-12-19 | 2020-05-19 | 石家庄禾柏生物技术股份有限公司 | 一种新型试剂添加系统 |
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| CN115041018B (zh) * | 2022-07-05 | 2023-04-11 | 重庆朗福环保科技有限公司 | 一种烟气捕集回收二氧化碳系统及其催化剂添加装置 |
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| CN211718319U (zh) * | 2019-12-19 | 2020-10-20 | 石家庄禾柏生物技术股份有限公司 | 一种新型试剂添加系统 |
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| CN211718319U (zh) * | 2019-12-19 | 2020-10-20 | 石家庄禾柏生物技术股份有限公司 | 一种新型试剂添加系统 |
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