WO2021019924A1 - Cathéter - Google Patents

Cathéter Download PDF

Info

Publication number
WO2021019924A1
WO2021019924A1 PCT/JP2020/022934 JP2020022934W WO2021019924A1 WO 2021019924 A1 WO2021019924 A1 WO 2021019924A1 JP 2020022934 W JP2020022934 W JP 2020022934W WO 2021019924 A1 WO2021019924 A1 WO 2021019924A1
Authority
WO
WIPO (PCT)
Prior art keywords
tip
catheter
tubular portion
tubular
proximal end
Prior art date
Application number
PCT/JP2020/022934
Other languages
English (en)
Japanese (ja)
Inventor
チャイヤモン ティティヤートン
チャイウィット ワンチャット
Original Assignee
朝日インテック株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 朝日インテック株式会社 filed Critical 朝日インテック株式会社
Publication of WO2021019924A1 publication Critical patent/WO2021019924A1/fr

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes

Definitions

  • the present invention relates to a catheter.
  • a guide catheter or the like to be inserted into a body cavity such as a blood vessel is required to have flexibility at its tip so that it can smoothly proceed inside a curved body cavity, for example.
  • the proximal end of the catheter is required to be rigid so that it is not pushed back from the position where the catheter is placed due to the operation of a device such as a guide wire used in combination with the catheter.
  • a catheter having a structure in which a tip is extended toward the tip side at the tip of a rigid outer tube is disclosed (see, for example, Patent Document 1).
  • the tip tip is made of a material that is more flexible than the outer tube, both the flexibility of the tip portion and the rigidity of the base end portion can be expected.
  • the tip tip and the outer side are compared with the case where the outer tube is bonded to the outer tube formed of a single layer. There is a high possibility that the tube will peel off.
  • the present invention has been made based on the above circumstances, and an object of the present invention is to provide a catheter having a rigid base end portion, a flexible tip portion, and being difficult to peel off.
  • a first tubular portion and a second tubular portion are provided.
  • the first tubular portion has a large diameter portion extending from the tip toward the proximal end side and extends from the proximal end of the large diameter portion toward the proximal end side and is smaller than the outer diameter of the large diameter portion. It has a small diameter part with an outer diameter, The outer circumference of the small diameter portion is covered with the second tubular portion.
  • a catheter in which the flexural rigidity of the material constituting the first tubular portion is smaller than the flexural rigidity of the material constituting the second tubular portion.
  • the catheter according to (1) or (2) which includes a braid that is at least partially embedded in the first tubular portion, and (4) the braid is the first tubular.
  • the "tip side” means a direction along the long axis direction of the catheter, in which the large diameter portion is located with respect to the small diameter portion of the first tubular portion.
  • the “base end side” means a direction along the long axis direction of the catheter and a direction opposite to the tip end side.
  • the “tip” refers to the end portion on the distal end side of any member or portion, and the “base end” indicates the end portion on the proximal end side of any member or portion.
  • the “tip portion” refers to a portion of any member or portion that includes the tip and extends halfway from the tip toward the proximal end side.
  • base end portion refers to a portion of any member or portion that includes the proximal end and extends halfway from the proximal end toward the distal end side.
  • Flexible rigidity refers to the "flexural modulus” specified in JIS K 7171 (2016).
  • the present invention can provide a catheter having a rigid base end and a flexible tip that is difficult to peel off.
  • the catheter includes a first tubular portion and a second tubular portion, and the first tubular portion includes a large-diameter portion extending from the tip toward the proximal end side and a base from the proximal end of the large-diameter portion. It is provided with a small diameter portion extending toward the end side and having an outer diameter smaller than the outer diameter of the large diameter portion, and the outer circumference of the small diameter portion is covered with the second tubular portion.
  • the bending rigidity of the material constituting the first tubular portion is smaller than the bending rigidity of the material constituting the second tubular portion.
  • the "tip portion of the catheter” particularly refers to a region in the long axis direction in which the large diameter portion of the first tubular portion is located.
  • FIG. 1A is a schematic side view of a partially cutaway showing the first embodiment of the present invention.
  • the catheter 1 is roughly composed of a first tubular portion 11, a second tubular portion 21, a braided body 31, a tip tip 41, and a connector 51. ..
  • the first tubular portion 11 is a longitudinal portion in which a through hole 11h penetrating from the tip end to the base end is formed.
  • the first tubular portion 11 includes a large diameter portion 11A and a small diameter portion 11B.
  • the large diameter portion 11A is a portion extending from the tip toward the base end side.
  • the large diameter portion 11A for example, one having a constant outer diameter along the major axis direction (see FIG. 1A), and at least a part of the outer diameter in the major axis direction gradually or gradually changes.
  • a combination of these (not shown) or the like can be exemplified.
  • the small diameter portion 11B is a portion that extends from the proximal end of the large diameter portion 11A toward the proximal end side and has an outer diameter smaller than the outer diameter of the large diameter portion 11A.
  • the small diameter portion 11B for example, one having a constant outer diameter along the major axis direction (see FIG. 1A), or at least a part of the outer diameter in the major axis direction gradually or gradually changes or An example of a combination of these (not shown) can be exemplified.
  • the outer circumference of the small diameter portion 11B is covered with a tubular (cylindrical) second tubular portion 21.
  • the tip of the second tubular portion 21 is continuous with the base end of the large diameter portion 11A.
  • the second tubular portion 21 and the large diameter portion 11A and / or the small diameter portion 11B may be fixed or merely in contact with each other.
  • a method of bonding using an adhesive, a method of welding by heating, or the like is adopted as the fixing method. Can be done.
  • the outer diameter of the tip of the second tubular portion 21 matches the outer diameter of the base end of the large diameter portion 11A in the first tubular portion 11, and the outer diameter of the tip of the second tubular portion 21 is The outer diameter of the large diameter portion 11A and the second tubular portion 21 coincides with the outer diameter of the base end of the large diameter portion 11A in the first tubular portion 11, and the outer diameter of the large diameter portion 11A is from the tip of the large diameter portion 11A to the second tubular portion 21. It is more preferable that the shape is constant over the base end, or that the outer diameter gradually decreases from the base end of the second tubular portion 21 toward the tip of the large diameter portion 11A. As a result, the catheter 1 can be smoothly advanced inside the body cavity.
  • Examples of the material constituting each of the first and second tubular portions 11 and 21 include resin materials such as polyamide, polyamide elastomer, polyolefin, polyester, polyester elastomer, polyurethane, polyurethane elastomer, silicone, and fluororesin. ..
  • the flexural rigidity of the material constituting the first tubular portion 11 can be configured to be smaller than the flexural rigidity of the material constituting the second tubular portion 21.
  • two kinds of the above materials may be combined, but the same kind of materials may be combined.
  • the rigidity of the base end portion and the flexibility of the tip end portion (large diameter portion 11A) can be imparted to the catheter 1.
  • the braided body 31 is a member that is at least partially embedded in the first tubular portion 11.
  • the braided body 31 can be formed, for example, by braiding in a mesh pattern using the strands 31a.
  • As the strand 31a one or more single wires or stranded wires can be used.
  • the single wire means one single wire
  • the stranded wire means a bundle of wires formed by twisting a plurality of single wires in advance.
  • at least a part of the braided body 31 may be embedded in the tip tip 41.
  • Examples of the material constituting the braided body 31 include stainless steel such as SUS304 and SUS316; platinum and tungsten; and resin materials such as reinforced plastic.
  • the catheter 1 can increase its own strength by embedding the braided body 31 in the first tubular portion 11, the first tubular portion 11 and the tip tip 41, and the catheter 1 can be increased. It is possible to prevent breakage, crushing, and kinking.
  • the tip tip 41 is a member extending from the tip of the first tubular portion 11 toward the tip side.
  • the tip tip 41 can be formed so as to taper toward the tip side, for example.
  • the tip tip 41 has a through hole 41h along the major axis direction, and the through hole 41h and the through hole 11h of the first tubular portion 11 communicate with each other.
  • the tip tip 41 can be formed of, for example, a material that is more flexible than the material that constitutes the first tubular portion 11.
  • Examples of the material constituting the tip chip 41 include resin materials such as polyurethane, polyurethane elastomer, polyamide, and polyamide elastomer.
  • the connector 51 is a member for which the operator grips the catheter 1.
  • the connector 51 has, for example, a through hole 51h that is connected to the base end portion of the first tubular portion 11 and communicates with the above-mentioned through hole 11h.
  • An opening 51a is formed at the end of the through hole 51h on the base end side.
  • the shape of the connector 51 is not particularly limited as long as the effect of the present invention is not impaired, and for example, the connector 51 can be formed into a shape that is easy for the operator to operate.
  • the lumen L is formed by the through hole 41h of the tip tip 41, the through hole 11h of the first tubular portion 11, and the through hole 51h of the connector 51.
  • a medical device such as a guide wire, a liquid such as a chemical solution, or the like is inserted into the lumen L through the opening 51a.
  • the usage mode of the catheter 1 will be described.
  • a procedure in which the catheter 1 is used as a guiding catheter and a stenosis formed in a coronary artery of the heart is expanded with a balloon catheter will be illustrated.
  • a guide wire A (not shown) is first inserted into a blood vessel, and the tip thereof is sent close to the entrance of the coronary artery of the heart.
  • the guide wire A is inserted into the lumen L of the catheter 1, and the catheter 1 is pushed forward along the guide wire A into the blood vessel so that the tip reaches the entrance of the coronary artery of the heart.
  • the catheter 1 is fed while following the curvature of the blood vessel.
  • the guide wire A is pulled out and replaced with a thinner guide wire B (not shown) for a balloon catheter, and the tip of the guide wire B reaches a position where it passes through the stenosis portion via the catheter 1.
  • a balloon catheter (not shown) is inserted along the guide wire B to the inside of the stenosis, and the stenosis is expanded by the balloon for treatment. After this treatment, the procedure is completed by removing the balloon catheter, the catheter 1, and the guide wire B in this order from the body.
  • the catheter 1 since the catheter 1 has the above configuration, the base end portion has rigidity, the tip end portion is flexible, and peeling of the tip end portion can be suppressed. As a result, the catheter 1 can be smoothly and surely delivered to a desired site in the body cavity without peeling off the tip portion (large diameter portion 11A) even if the blood vessel is complicatedly curved.
  • FIG. 2 is a schematic side view of a partially cutaway showing a second embodiment of the present invention.
  • the catheter 2 is roughly composed of a first tubular portion 12, a second tubular portion 22, a braided body 31, a tip tip 41, and a connector 51. ..
  • the catheter 2 differs from the first embodiment in that it includes a first tubular portion 12 and a second tubular portion 22. Since the configurations of the braided body 31, the tip tip 41, and the connector 51 are the same as those of the first embodiment, the same parts are designated by the same reference numerals and detailed description thereof will be omitted. Further, since the configurations other than the configurations of the first tubular portion 12 and the second tubular portion 22 and the usage mode of the catheter 2 shown below are the same as those of the first embodiment, the description thereof will be omitted. ..
  • the first tubular portion 12 includes a large diameter portion 12A and a small diameter portion 12B.
  • the large diameter portion 12A extends from the tip toward the proximal end side.
  • the small diameter portion 12B is formed so as to extend from the proximal end of the large diameter portion 11A toward the proximal end side and to be smaller than the outer diameter of the large diameter portion 12A.
  • the catheter 2 has a tapered portion 12Ba in which the tip portion of the small diameter portion 12B gradually decreases in outer diameter toward the proximal end side.
  • the second tubular portion 22 covers the outer circumference of the small diameter portion 12B.
  • the second tubular portion 22 is provided so that the tip portion covers the tapered portion 12Ba of the small diameter portion 12B, and the outer diameter of the second tubular portion 22 is constant along the major axis direction.
  • the thickness of the second tubular portion 22 can be formed so as to increase from the tip end to the proximal end side on the outer peripheral surface of the tapered portion 12Ba.
  • the catheter 2 since the catheter 2 has the above configuration, it is possible to avoid a sudden change in rigidity at the boundary portion between the large diameter portion 12A and the small diameter portion 12B, and a kink occurs at the boundary portion. Can be suppressed. Further, when the tip portion of the second tubular portion 22 is fixed to the tapered portion 12Ba, the contact area between the two can be increased, and the first tubular portion 12 and the second tubular portion 22 are separated from each other. It becomes difficult.
  • FIG. 3 is a schematic side view of a partial notch showing a third embodiment of the present invention.
  • the catheter 3 is roughly composed of a first tubular portion 13, a second tubular portion 23, a braided body 33, a tip tip 41, and a connector 51. ..
  • the catheter 3 differs from the first embodiment in that it includes a first tubular portion 13, a second tubular portion 23, and a braided body 33. Since the configurations of the tip tip 41 and the connector 51 are the same as those of the first embodiment, the same parts are designated by the same reference numerals and detailed description thereof will be omitted.
  • the configurations other than the configurations of the first tubular portion 13, the second tubular portion 23, and the braided body 33 shown below, and the usage mode of the catheter 3 are the same as those of the first embodiment. The explanation is omitted.
  • the first tubular portion 13 includes a large diameter portion 13A and a small diameter portion 13B.
  • the large diameter portion 13A extends from the tip toward the proximal end side.
  • the small diameter portion 13B is formed so as to extend from the proximal end of the large diameter portion 13A toward the proximal end side and to be smaller than the outer diameter of the large diameter portion 13A.
  • the second tubular portion 23 covers the outer circumference of the small diameter portion 13B.
  • the braided body 33 is a member whose at least a part is embedded in the first tubular portion 13.
  • the braided body 33 is embedded so as to straddle the first tubular portion 13 and the second tubular portion 23.
  • the tip portion 33A and the base end portion 33C are embedded in the first tubular portion 13
  • the intermediate portion 33B between the tip portion 33A and the base end portion 33C is the second. It can be embedded in the tubular portion 23.
  • the tip portion 33A and the intermediate portion 33B, and / or the intermediate portion 33B and the base end portion 33C are respectively continuous strands 33a.
  • the braided body 33 is embedded so as to straddle the first tubular portion 13 and the second tubular portion 23, so that the first tubular portion is formed.
  • the connection strength between the portion 13 and the second tubular portion 23 can be increased, and the second tubular portion 23 can be suppressed from peeling from the first tubular portion 13.
  • the catheters 1 to 3 having the braided bodies 31, 33, the tip tip 41, and the connector 51 have been described, but even if the catheter does not have at least one of these.
  • the catheter may be a catheter 1m1 (see FIG. 4A) having a first tubular portion 11m1, a second tubular portion 21 and a connector 51, and the first tubular portion 11m2 and the second.
  • a catheter 1 m2 (see FIG. 4B) having a tubular portion 21, a braided body 31 m2 (for example, one whose tip is embedded up to a large diameter portion of the first tubular portion 11 m2) and a connector 51. May be good.
  • the catheter in which the tip end portion 33A and the base end portion 33C of the braided body 33 are embedded in the first tubular portion 13 and the intermediate portion 33B is embedded in the second tubular portion 23.
  • the third has been described, it is sufficient that at least a part of the braided body is embedded in the first tubular portion of the catheter.
  • examples of such a catheter include a catheter 1m3 in which the tip portion 33Am3 of the braided body 33m3 is embedded in the first tubular portion 13m3 and the proximal end portion 33Cm3 is embedded in the second tubular portion 23m3 (see FIG. 5A).
  • a long axis in which a catheter 1m4 see FIG.
  • a tip portion 33Am4 of a braided body 33m4 is embedded in a second tubular portion 23m4 and a base end portion 33Cm4 is embedded in a first tubular portion 13m4 and a small diameter portion 13Bm5 are arranged.
  • the braided body 33m5 is sandwiched between the first tubular portion 13m5 and the second tubular portion 23m5 so that the strands constituting the braided body 33m5 are sandwiched between the first tubular portion 13m5 and the second tubular portion 23m5 at the portion in the direction.
  • a catheter 1 m5 (see FIG. 5C) embedded so as to straddle the tubular portion 23 m5 of the above.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

L'objectif de la présente invention est de fournir un cathéter dans lequel une section d'extrémité proximale possède une rigidité et une section d'extrémité distale est flexible et peu susceptible de se décoller.　Un cathéter 1 comprend une première partie tubulaire 11 et une seconde partie tubulaire 21, la première partie tubulaire 11 étant formée : de manière à être équipée d'une section de grand diamètre 11A qui s'étend vers une extrémité proximale à partir d'une extrémité distale et d'une section de petit diamètre 11B qui est disposée de façon à s'étendre vers l'extrémité proximale à partir d'une extrémité proximale de la section de grand diamètre 11A et qui a un diamètre externe plus petit que le diamètre externe de la section de grand diamètre 11A ; de telle sorte que la circonférence externe de la section de petit diamètre 11B est recouverte par la seconde partie tubulaire 21 ; et de telle sorte que la rigidité à la flexion d'un matériau formant la première partie tubulaire 11 devient inférieure à la rigidité à la flexion d'un matériau formant la seconde partie tubulaire 21.
PCT/JP2020/022934 2019-07-31 2020-06-10 Cathéter WO2021019924A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2019141752A JP2021023443A (ja) 2019-07-31 2019-07-31 カテーテル
JP2019-141752 2019-07-31

Publications (1)

Publication Number Publication Date
WO2021019924A1 true WO2021019924A1 (fr) 2021-02-04

Family

ID=74229805

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2020/022934 WO2021019924A1 (fr) 2019-07-31 2020-06-10 Cathéter

Country Status (2)

Country Link
JP (1) JP2021023443A (fr)
WO (1) WO2021019924A1 (fr)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09506541A (ja) * 1995-04-28 1997-06-30 ターゲット セラピューティクス， インコーポレイテッド 高性能ブレードカテーテル
JPH11347129A (ja) * 1998-05-20 1999-12-21 Smiths Ind Plc 医療外科手術用チュ―ブおよびその製造方法
JP2005501613A (ja) * 2001-08-31 2005-01-20 ボストン サイエンティフィック リミテッド 改良型遠位先端および移行部を備えたマイクロカテーテル
JP2017140242A (ja) * 2016-02-10 2017-08-17 テルモ株式会社 医療用長尺体、およびバルーンカテーテル
WO2019026220A1 (fr) * 2017-08-02 2019-02-07 朝日インテック株式会社 Cathéter

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6754270B2 (ja) * 2016-10-21 2020-09-09 テルモ株式会社 カテーテル組立体

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09506541A (ja) * 1995-04-28 1997-06-30 ターゲット セラピューティクス， インコーポレイテッド 高性能ブレードカテーテル
JPH11347129A (ja) * 1998-05-20 1999-12-21 Smiths Ind Plc 医療外科手術用チュ―ブおよびその製造方法
JP2005501613A (ja) * 2001-08-31 2005-01-20 ボストン サイエンティフィック リミテッド 改良型遠位先端および移行部を備えたマイクロカテーテル
JP2017140242A (ja) * 2016-02-10 2017-08-17 テルモ株式会社 医療用長尺体、およびバルーンカテーテル
WO2019026220A1 (fr) * 2017-08-02 2019-02-07 朝日インテック株式会社 Cathéter

Also Published As

Publication number Publication date
JP2021023443A (ja) 2021-02-22

Similar Documents

Publication Publication Date Title
US10166363B2 (en) Catheter
US6991616B2 (en) Steerable device for introducing diagnostic and therapeutic apparatus into the body
KR20220071259A (ko) 카테터
JP5869235B2 (ja) 医療用器具
WO2019215827A1 (fr) Tube à usage médical
WO2016035739A1 (fr) Cathéter
EP3130372A1 (fr) Cathéter et cathéter à ballonnet
JPWO2020162287A1 (ja) 延長カテーテル、及びその製造方法
JP6307387B2 (ja) カテーテル
JP2006271901A (ja) コイル状造影マーカーとその製造方法、及びカテーテル
JP5898861B2 (ja) 医療用器具
WO2021019924A1 (fr) Cathéter
WO2016035740A1 (fr) Cathéter
JP6847274B2 (ja) カテーテル
JP6850368B2 (ja) カテーテル
JP6633513B2 (ja) カテーテル及びカテーテルセット
WO2022239763A1 (fr) Cathéter
US20220323720A1 (en) Support catheter and tube
JP6307389B2 (ja) カテーテル
WO2024004824A1 (fr) Cathéter
JP7060454B2 (ja) 医療用チューブ
WO2022158366A1 (fr) Bobine à couches multiples
WO2022185624A1 (fr) Cathéter à ballonnet
JP6864110B2 (ja) ガイドワイヤ
JP6307388B2 (ja) カテーテル及びその製造方法

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 20846989

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 20846989

Country of ref document: EP

Kind code of ref document: A1