WO2021000255A1 - Dispositif de collecte d'humeur aqueuse - Google Patents

Dispositif de collecte d'humeur aqueuse Download PDF

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Publication number
WO2021000255A1
WO2021000255A1 PCT/CN2019/094383 CN2019094383W WO2021000255A1 WO 2021000255 A1 WO2021000255 A1 WO 2021000255A1 CN 2019094383 W CN2019094383 W CN 2019094383W WO 2021000255 A1 WO2021000255 A1 WO 2021000255A1
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WO
WIPO (PCT)
Prior art keywords
outer cylinder
aqueous humor
puncture needle
collection device
peripheral wall
Prior art date
Application number
PCT/CN2019/094383
Other languages
English (en)
Chinese (zh)
Inventor
赵潺
Original Assignee
北京华视诺维医疗科技有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 北京华视诺维医疗科技有限公司 filed Critical 北京华视诺维医疗科技有限公司
Priority to PCT/CN2019/094383 priority Critical patent/WO2021000255A1/fr
Priority to PCT/CN2019/110062 priority patent/WO2021000440A1/fr
Priority to US17/624,393 priority patent/US20220354468A1/en
Priority to JP2021577950A priority patent/JP7337967B2/ja
Priority to PCT/CN2020/096860 priority patent/WO2021000743A1/fr
Priority to EP20834808.6A priority patent/EP3995215A4/fr
Publication of WO2021000255A1 publication Critical patent/WO2021000255A1/fr
Priority to IL289549A priority patent/IL289549A/en
Priority to JP2023134836A priority patent/JP2023164441A/ja

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery

Definitions

  • the invention relates to the technical field of medical appliances, in particular to an aqueous humor collection device.
  • Anterior chamber puncture of the eye is a medical technology that pierces the cornea of the eye to make the aqueous humor flow out. It has important application value in ophthalmology clinical research work. It is mainly used to reduce intraocular pressure, aqueous humor collection and other therapeutic pretreatments. Room discharge.
  • the present invention provides an aqueous humor collection device that can control the drainage speed of aqueous humor during the puncture process, and can avoid contamination of the aqueous humor after collection and waste due to transfer , Thereby improving safety and reliability.
  • an aqueous humor collection device which includes:
  • the outer cylinder is provided with a puncture needle installation end and a liquid sampling tube installation end at both axial ends;
  • the puncture needle is fixedly installed at the puncture needle installation end and is provided with an inner end of the puncture needle located in the barrel cavity of the outer cylinder and an outer end of the puncture needle located outside the barrel cavity of the outer cylinder;
  • the liquid sampling tube assembly includes a liquid sampling tube that is inserted into the outer cylinder cavity from the installation end of the liquid sampling tube and can be inserted and removed in an axial direction, and is arranged in the outer cylinder cavity for The pipe plug for sealing the nozzle of the liquid sampling pipe;
  • the static friction coefficient between the pipe plug and the inner peripheral wall of the outer cylinder is ⁇ 1
  • the static friction coefficient between the pipe plug and the nozzle of the liquid collection tube is ⁇ 2, and satisfies: ⁇ 1 ⁇ 2;
  • the pipe plug is arranged at intervals on the inner peripheral wall of the outer cylinder.
  • smooth contact is formed between the pipe plug and the inner peripheral wall of the outer cylinder.
  • the aqueous humor collection device further includes an anti-sloshing structure for limiting the displacement of the liquid sampling tube assembly along the radial direction of the outer cylinder cavity.
  • the anti-sloshing structure includes an annular groove formed on the outer peripheral wall of the liquid sampling tube assembly and an annular stopper arranged around the annular groove. The radial direction of the annular stopper The outer end abuts against the inner peripheral wall of the outer cylinder.
  • the annular limiting member is a rubber band.
  • the groove side wall of the annular groove is formed with a groove vent hole penetrating along the axial direction of the outer cylinder cavity, and the outer cylinder cavity is between the pipe plug and the piercing hole.
  • the barrel cavity area between the needle mounting ends communicates with the groove vent.
  • the aqueous humor collection device further includes a needle holder for fixing the puncture needle, and a quick plug connection is formed between the inner end of the needle holder and the puncture needle installation end.
  • a threaded connection or a snap connection is formed between the inner end of the needle holder and the puncture needle mounting end.
  • the aqueous humor collection device further includes an anti-puncture spacer for isolating the inner end of the puncture needle from the tube plug along the axial direction of the outer cylinder cavity, the anti-puncture spacer It is a detachable piece.
  • the peripheral wall of the outer cylinder is provided with a spacer insertion groove, and the outer cylinder cavity is connected to the spacer insertion groove in the region of the cylinder cavity between the inner end of the puncture needle and the pipe plug.
  • a slot, the anti-puncture spacer is inserted into the barrel cavity area through the spacer insertion slot.
  • the liquid sampling tube assembly is provided with a tube plug so that the liquid sampling tube lumen is in a negative pressure state.
  • the inner end of the puncture needle pierces the tube plug to drain aqueous humor to the liquid sampling tube lumen
  • the amount of fluid in the lumen gradually increases, and the difference between the pressure in the lumen and the pressure in the anterior chamber gradually decreases, so the drainage speed of the aqueous humor is gradually reduced, thereby avoiding the dangerous situation of sudden drop in intraocular pressure and greatly improving safety.
  • the static friction coefficient ⁇ 1 between the pipe plug and the inner peripheral wall of the outer cylinder is smaller than the static friction coefficient between the pipe plug and the nozzle of the liquid sampling tube, which is ⁇ 2, or the pipe plug is arranged at intervals on the inner peripheral wall of the outer cylinder, Ensure that when the liquid sampling tube assembly is pulled out from the outer barrel cavity, the pipe plug always tightly blocks the liquid sampling tube nozzle, avoiding the contact of the aqueous humor in the lumen with the external environment, and ensuring the quality of the collected aqueous humor. Purity, and can avoid the waste caused by the transfer of aqueous humor, thereby improving the reliability of subsequent detection.
  • Figure 1 is a perspective view of an aqueous humor collection device in a specific embodiment of the present invention
  • Figure 2 is a front view of the aqueous humor collection device in Figure 1;
  • FIG. 3 is a main cross-sectional view of the aqueous humor collection device in FIG. 2 when the puncture needle does not pierce the tube plug;
  • Figure 4 is a main cross-sectional view of the aqueous humor collection device in Figure 3 when a puncture-proof partition is provided;
  • Figure 5 is a cross-sectional view of the aqueous humor collection device in Figure 1;
  • Fig. 6 is a schematic structural diagram of the puncture needle of the aqueous humor collection device in Fig. 3 when a peripheral wall water outlet hole is provided;
  • Fig. 7 is a schematic structural view of the pipe plug of the aqueous humor collection device in Fig. 3 provided with an open peripheral wall and semicircular pipe plug exhaust channel;
  • Fig. 8 is a schematic structural view of the pipe plug of the aqueous humor collection device in Fig. 3 provided with an open peripheral wall and a semi-rectangular pipe plug exhaust channel;
  • Fig. 9 is a schematic structural diagram of the pipe plug of the aqueous humor collection device in Fig. 3 when a peripheral wall closed and circular pipe plug exhaust channel is provided;
  • Fig. 10 is a schematic structural diagram of the pipe plug of the aqueous humor collection device in Fig. 3 when a peripheral wall closed and arc-shaped pipe plug exhaust channel is provided;
  • FIG. 11 is a schematic structural diagram of the liquid collection tube and the supporting tube frame of the aqueous humor collection device in FIG. 3 when connected by a buckle;
  • FIG. 12 is a schematic structural diagram of the liquid collection tube of the aqueous humor collection device in the specific embodiment of the present invention when a convex point-like limiting protrusion is integrally formed;
  • FIG. 13 is a schematic diagram of the structure of the liquid collection tube of the aqueous humor collection device in the specific embodiment of the present invention when a corrugated limiting protrusion is integrally formed;
  • FIG. 14 is a schematic structural view of the liquid collection tube of the aqueous humor collection device in the specific embodiment of the present invention when the tube kit is sheathed and the limiting protrusion is in the shape of a convex point;
  • 15 is a schematic structural diagram of the liquid collection tube of the aqueous humor collection device in the specific embodiment of the present invention when the tube kit is sheathed and the limiting protrusion is corrugated;
  • FIG. 16 is a schematic structural view of the liquid collection tube of the aqueous humor collection device in the specific embodiment of the present invention when the tube kit is sheathed and the limiting protrusion is in the shape of a helical tooth;
  • FIG. 17 is a schematic structural diagram of the supporting pipe frame of the aqueous humor collection device in the specific embodiment of the present invention when a convex point-like limiting protrusion is integrally formed;
  • FIG. 18 is a schematic structural diagram of the supporting pipe frame of the aqueous humor collection device in the specific embodiment of the present invention when a corrugated limiting protrusion is integrally formed;
  • FIG. 19 is a schematic diagram of the structure of the supporting tube frame of the aqueous humor collection device in the specific embodiment of the present invention when the oblique tooth-shaped limiting protrusion is integrally formed;
  • 20 is a schematic structural diagram of the supporting tube frame of the aqueous humor collection device in the specific embodiment of the present invention when the tube kit is sheathed and the limiting protrusion is in the shape of a convex point;
  • 21 is a schematic structural diagram of the supporting tube frame of the aqueous humor collection device in the specific embodiment of the present invention when the tube kit is sheathed and the limiting protrusion is corrugated;
  • FIG. 22 is a schematic diagram of the structure of the supporting tube frame of the aqueous humor collection device in the specific embodiment of the present invention when the tube kit is sheathed and the limiting protrusion is in the shape of an oblique tooth.
  • an exemplary embodiment of the present invention provides an aqueous humor collection device 100, which includes an outer cylinder 1, a puncture needle 2, and a collection tube assembly 3.
  • the outer cylinder 1 is provided with a puncture needle installation end and a liquid sampling tube installation end at both ends in the axial direction.
  • the puncture needle 2 is fixedly installed at the installation end of the puncture needle and is provided with an inner end of the puncture needle located in the cavity of the outer cylinder and an outer end of the puncture needle located outside the cavity of the outer cylinder.
  • the sampling tube assembly 3 includes a sampling tube 31 that is inserted from the installation end of the sampling tube into the barrel cavity of the outer cylinder and can be inserted and removed in the axial direction, and is arranged in the outer cylinder cavity for sealing the nozzle of the sampling tube.
  • the pipe plug 33 the static friction coefficient between the tube plug 33 and the inner peripheral wall of the outer cylinder is ⁇ 1, and the static friction coefficient between the tube plug 33 and the nozzle of the liquid collection tube is ⁇ 2, and satisfies: ⁇ 1 ⁇ 2.
  • the pipe plug 33 may be spaced apart from the inner peripheral wall of the outer cylinder to ensure that the pipe plug 33 and the inner peripheral wall of the outer cylinder do not contact each other.
  • the fluid collection tube assembly 3 can be moved toward the inner end of the puncture needle, so that the inner end of the puncture needle pierces the soft sleeve 8 and the tube plug 33 Then, it is inserted into the lumen of the liquid collection tube to drain the aqueous humor in the anterior chamber to the lumen of the liquid collection tube through the outer end of the puncture needle and the inner end of the puncture needle.
  • the lumen of the liquid sampling tube is always in a negative pressure state, but as the amount of liquid in the lumen gradually increases, the pressure in the lumen and the pressure in the anterior chamber The difference is gradually reduced, so the drainage speed of aqueous humor will gradually decrease, so as to avoid the dangerous situation of sudden drop in intraocular pressure, and greatly improve the safety of puncture drainage.
  • the sampling tube assembly 3 can be pulled out from the outer cylinder cavity as a whole, and then the sampling tube 31 can be directly placed in a specific detection instrument for specific item detection, which is consistent with the prior art
  • the aqueous humor in the lumen of the liquid collection tube can be prevented from contacting the external environment, and the purity of the collected aqueous humor can be ensured, thereby improving the accuracy and reliability of subsequent testing It can avoid the waste caused by transferring aqueous humor.
  • the static friction coefficient ⁇ 1 between the pipe plug 33 and the inner peripheral wall of the outer cylinder is smaller than the static friction coefficient between the pipe plug 33 and the nozzle of the liquid sampling tube, which is ⁇ 2, or the pipe plug 33 is spaced from the inner peripheral wall of the outer cylinder
  • the setting can ensure that when the liquid sampling tube assembly 3 is pulled out from the outer cylinder cavity as a whole, the tube plug 33 will always tightly block the liquid sampling tube nozzle, thereby more reliably ensuring the purity of the collected aqueous humor .
  • the pipe plug 33 and the inner peripheral wall of the outer cylinder are preferably arranged in contact with each other through a smooth surface.
  • the radially outer end surface of the pipe plug 33 or the inner peripheral wall surface of the outer cylinder can be set as a smooth surface, or the radial outer end surface of the pipe plug 33 and the inner peripheral wall surface of the outer cylinder can be set as smooth surfaces at the same time.
  • the aqueous humor collection device 100 includes an anti-sloshing structure for limiting the displacement of the sampling tube assembly 3 along the radial direction of the outer cylinder cavity. Under this structure, it can be ensured that the liquid sampling tube assembly 3 only moves in the axial direction during the insertion and removal movement without radial shaking, which not only ensures that the inner end of the puncture needle can accurately pierce the tube plug 33 during the puncture process. Inserted into the lumen of the liquid collection tube, it can also ensure that the liquid collection tube assembly 3 is stably pulled out after the aqueous humor collection is completed, so as to avoid the leakage of aqueous humor in the liquid collection tube lumen, thereby further improving the accuracy and accuracy of subsequent detection. reliability.
  • the anti-sloshing structure may include an annular groove 35 formed on the outer peripheral wall of the liquid sampling tube assembly 3 and an annular stopper 37 provided in the hoop annular groove 35.
  • the annular stopper 37 The radially outer end of 37 abuts against the inner peripheral wall of the outer cylinder. It should be noted that, in addition to preventing the radial sloshing of the liquid sampling tube assembly 3, the annular stopper 37 can make the inner end of the puncture needle pierce the tube plug 33 more accurately and prevent deviation during the puncture process.
  • the stability and reliability of the puncture drainage process are effectively improved.
  • the liquid sampling tube assembly 3 can be prevented from being separated from the outer cylinder when the aqueous humor collection device 100 is taken, thereby improving the reliability of the product.
  • multiple sets of annular grooves 35 and corresponding annular stoppers 37 can be provided to obtain better effects.
  • the annular limiter 37 can be preferably set as an easy-to-obtain, inexpensive and good-quality rubber band or other elastic ring, and the annular limiter 37 made of elastic material and the inner peripheral wall of the outer cylinder The formation of elastic contact between them can avoid excessive friction and abrasion of the inner peripheral wall of the outer cylinder.
  • a groove vent 36 penetrating along the axial direction of the outer cylinder cavity can be formed on the groove side wall of the annular groove 35, so that the outer cylinder cavity is between the pipe plug 33 and the puncture needle installation end.
  • the area of the barrel cavity can be communicated with the atmosphere through the groove vent 36, so as to avoid the formation of an air plug in the barrel cavity of the outer cylinder and affect the smooth plugging and unplugging of the liquid collection tube assembly 3, thereby improving the reliability of the use of the aqueous humor collection device 100 Sex.
  • the anti-sloshing structure may also include a limiting protrusion 6 protruding from the outer peripheral wall of the liquid sampling tube assembly 3 or from the inner peripheral wall of the outer cylinder, and radial ends of the limiting protrusion 6
  • the outer circumferential wall of the liquid sampling tube assembly 3 and the inner circumferential wall of the outer cylinder are respectively connected to prevent the liquid sampling tube assembly 3 from sloshing radially.
  • the limiting protrusion 6 When the limiting protrusion 6 is provided on the outer peripheral wall of the liquid sampling tube assembly 3, the limiting protrusion 6 can be integrally formed on the outer peripheral wall of the liquid sampling tube 31.
  • a tube set 34 sheathed on the outer peripheral wall of the liquid sampling tube 31 can be provided in the sampling tube assembly 3, and the limiting protrusion 6 can be provided on the outer peripheral wall of the tube set 34, because the tube set 34 is detachable Therefore, it can be reused, and it is relatively less difficult to form the limiting protrusion 6 on the tube sleeve 34, which is more conducive to reducing production costs.
  • the tube set 34 can be set as an elastic tube set to prevent the liquid sampling tube 31 from rupturing due to rigid contact when subjected to a radial restriction, thereby reducing the risk of aqueous humor leakage.
  • the anti-sloshing structure may include a plurality of limiting protrusions 6 arranged at intervals in the circumferential direction to ensure that the liquid sampling tube 31 is coaxially arranged with the outer cylinder cavity, thereby ensuring that the liquid sampling tube 31 is arranged along the Axial smooth plug-in movement.
  • a vent gap is formed between the plurality of spacing protrusions 6 spaced apart, the barrel cavity of the outer cylinder body between the puncture needle installation end and the pipe plug 33 can communicate with the atmosphere through the vent gap , Thereby avoiding the formation of a gas plug in the cavity of the outer cylinder and affecting the smooth insertion and removal of the liquid sampling tube assembly 3.
  • a plurality of limiting protrusions 6 arranged at intervals along the circumferential direction may be arranged in a convex point shape.
  • the limiting protrusion 6 may also be continuously extended in the circumferential direction.
  • an exhaust gap is preferably formed between the limiting protrusion 6 and the outer peripheral wall of the liquid sampling tube assembly 3 to avoid the formation of a gas plug.
  • an exhaust gap is also preferably formed between the limiting protrusion 6 and the inner peripheral wall of the outer cylinder.
  • the limiting protrusions 6 continuously extending in the circumferential direction may be arranged in a corrugated shape or a helical tooth shape.
  • the limiting protrusions 6 are arranged at intervals along the tube length direction of the liquid sampling tube assembly 3, or are continuously extended and formed along the tube length direction, it is preferable to limit the protrusions 6
  • the total span of the position protrusion 6 along the length of the tube is set to be not less than half of the length of the liquid sampling tube. In other words, when the number of limiting protrusions 6 arranged along the length of the tube is large enough, the formation of a lever fulcrum on the outer peripheral wall of the sampling tube assembly 3 can be avoided, thereby more reliably preventing the sampling tube assembly 3 from shaking in the radial direction. .
  • the liquid sampling tube assembly 3 further includes a supporting tube frame 32 for fixing the liquid sampling tube 31.
  • the anti-sloshing structure can be arranged between the outer peripheral wall of the support pipe frame 32 and the inner peripheral wall of the outer cylinder, for example, as shown in FIGS. 17 to 22.
  • the supporting tube frame 32 can better improve the stability of the liquid sampling tube assembly 3 and reduce the risk of the liquid sampling tube assembly 3 being broken due to collision or pressing.
  • the connection method between the liquid sampling tube 31 and the support tube frame 32 must meet the requirements of stability and quick disassembly.
  • the liquid sampling tube 31 and the support tube frame 32 can be fixed by screw connection or snap connection.
  • the sampling tube 31 and the supporting tube frame 32 are connected by a snap.
  • the sampling tube 31 needs to be inserted into the supporting tube frame 32, the sampling tube 31 is pushed to the right until the tube The rack buckle 321 is clamped into the liquid collection tube clamping groove 311, so that the liquid collection tube 31 and the supporting tube rack 32 can be locked and locked with each other.
  • the tube rack buckle button 322 can be pressed to lift the tube rack buckle 321 to escape the liquid sampling tube clamping groove 311, and the liquid sampling tube 31 can be quickly taken out from the supporting tube rack 32.
  • the aqueous humor collection device 100 further includes a needle holder 4 for fixing the puncture needle 2.
  • the outer end of the puncture needle protrudes from the outer end of the needle holder and the inner end of the puncture needle protrudes from the inner end of the needle holder, and a quick plug-in connection is formed between the inner end of the needle holder and the installation end of the puncture needle, which helps reduce the difficulty of installation. Thereby improving assembly efficiency.
  • a threaded connection or a snap-fit connection can be formed between the inner end of the needle holder and the puncture needle installation end.
  • the aqueous humor collection device 100 further includes an anti-puncture spacer 5, which is used to isolate the inner end of the puncture needle and the tube plug 33 from each other along the axial direction of the outer cylinder cavity. This prevents the inner end of the puncture needle from piercing the tube plug 33 when the aqueous humor collection device 100 is not used for anterior chamber puncture, which effectively prevents the device from failing before being used.
  • the puncture-proof partition 5 can prevent the aqueous humor collection device 100 from failing.
  • the anti-puncture spacer 5 is set as a detachable piece, and the anti-puncture spacer 5 can be removed before the puncture.
  • a spacer inserting groove 11 can be provided on the peripheral wall of the outer cylinder 1, and the spacer inserting groove 11 and the outer cylinder cavity are in the cylindrical cavity between the inner end of the puncture needle and the pipe plug 33.
  • the areas communicate with each other, and the anti-puncture spacer 5 can be inserted into the barrel cavity area through the spacer insertion slot 11, and placed between the inner end of the puncture needle and the tube plug 33, thereby connecting the inner end of the puncture needle and the tube plug 33 33 are isolated from each other.
  • the puncture-proof spacer 5 needs to be removed, it can be quickly pulled out from the spacer insertion slot 11, which is quite convenient for operation.
  • the tube plug 33 in order to better avoid the formation of a gas plug in the cavity of the outer cylinder and affecting the smooth insertion and removal of the liquid sampling tube assembly 3, the tube plug 33 can be placed radially outward
  • the rim forms a pipe plug exhaust passage 331 arranged along the extension direction of the outer barrel cavity, and the barrel cavity area of the outer barrel cavity between the pipe plug 33 and the puncture needle installation end can pass through the pipe plug exhaust passage 331
  • the peripheral wall exhaust gap between the above-mentioned liquid sampling tube 31 and the inner peripheral wall of the outer cylinder communicates with the atmosphere.
  • the barrel cavity of the outer cylinder is in the barrel cavity area between the pipe plug 33 and the puncture needle mounting end, the pipe plug exhaust passage 331 and the peripheral wall exhaust gap are in sequence connected, and the atmospheric environment is connected in sequence.
  • a plurality of pipe plug exhaust passages 331 that extend along the axial direction of the outer cylinder cavity and are sequentially spaced along the circumferential direction of the pipe plug 33 are provided.
  • the specific shape of the pipe plug exhaust passage 331 may be determined according to actual needs.
  • a pipe plug exhaust groove serving as the pipe plug exhaust passage 331 may be formed on the outer peripheral wall of the pipe plug 33
  • the exhaust groove of the pipe plug is provided with a groove opening facing the radially outer side.
  • the plug exhaust passage 331 may be set as an exhaust passage with an open peripheral wall.
  • the peripheral wall of the pipe plug exhaust channel 331 can be set as a closed peripheral wall, that is, the pipe plug exhaust channel 331 can be set as a peripheral wall closed exhaust channel.
  • the cross-section of the pipe plug exhaust passage 331 can be set to have different shapes such as a semicircle, a square or an arc.
  • the pipe plug 33 includes a pipe plug center portion for sealing the nozzle of the liquid extraction pipe and an outer ring portion of the pipe plug located radially outside the pipe plug center portion and provided with a pipe plug exhaust channel 331, which is To ensure internal and external ventilation, the outer ring portion of the pipe plug can be at least partially set as a loose ventilation structure, but it is still necessary to ensure that the central portion of the pipe plug has a tightness.
  • a puncture guide hole 332 for guiding the inner end of the puncture needle can be provided at the end of the tube plug 33.
  • the outer contour shape of the inner end of the puncture needle and the shape of the blind guide hole 332 are matched with each other.
  • the inner end of the puncture needle and the puncture blind guide hole 332 may be set in a long tapered shape that matches with each other.
  • the peripheral wall water outlet hole 21 communicating with the needle cavity of the puncture needle 2 can be provided on the outer peripheral wall of the inner end of the puncture needle.
  • the axial distance between the peripheral wall outlet hole 21 and the axial outlet hole 22 should not be too large, otherwise when the axial outlet hole 22 is inserted into the lumen of the liquid sampling tube, the peripheral wall outlet hole 21 is still located in the pipe plug 33 and is blocked. As a result, the water outlet hole 21 of the peripheral wall loses its effectiveness.
  • the axial distance between the hole center of the peripheral wall water outlet hole 21 and the hole center of the axial water outlet hole 22 can be preferably set to be no more than 3mm to ensure that when the axial water outlet hole 22 is inserted into the lumen of the liquid collection tube, the peripheral wall
  • the water outlet 21 can also be located in the lumen of the liquid sampling tube without being blocked.
  • first and second are only used for descriptive purposes, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of indicated technical features. Therefore, the features defined with “first” and “second” may explicitly or implicitly include at least one of the features. In the description of the present invention, "a plurality of” means at least two, such as two, three, etc., unless otherwise specifically defined.
  • the terms “installed”, “connected”, “connected”, “fixed” and other terms should be understood in a broad sense, for example, it can be a fixed connection or a detachable connection. , Or integrated; it can be mechanically connected, or it can be electrically connected or can communicate with each other; it can be directly connected or indirectly connected through an intermediate medium, it can be the internal communication of two components or the interaction relationship between two components, Unless otherwise clearly defined.
  • the specific meaning of the above-mentioned terms in the present invention can be understood according to specific circumstances.
  • the first feature “on” or “under” the second feature may be in direct contact with the first and second features, or the first and second features may be indirectly through an intermediary. contact.
  • the "above”, “above” and “above” of the first feature on the second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the level of the first feature is higher than the second feature.
  • the “below”, “below” and “below” of the second feature of the first feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the level of the first feature is smaller than the second feature.

Abstract

L'invention concerne un dispositif de collecte d'humeur aqueuse (100), comprenant : un cylindre externe (1), le cylindre externe étant pourvu d'une extrémité de montage d'aiguille de ponction (2) et d'une extrémité de montage de tuyau de collecte de liquide (31) ; une aiguille de ponction (2), l'aiguille de ponction étant disposée de manière fixe au niveau de l'extrémité de montage d'aiguille de ponction (2) et étant pourvue d'une extrémité interne d'aiguille de ponction (2) située à l'intérieur d'une cavité de cylindre externe (1) et d'une extrémité externe d'aiguille de ponction (2) située à l'extérieur de la cavité de cylindre externe (1) ; et un ensemble tuyau de collecte de liquide (3), l'ensemble tuyau de collecte de liquide comprenant un tuyau de collecte de liquide (31) inséré dans la cavité de cylindre externe (1) à partir de l'extrémité de montage de tuyau de collecte de liquide (31) et pouvant se déplacer dans une direction axiale d'une manière enfichable et un bouchon de tuyau (33) disposé dans la cavité de cylindre externe (1) pour sceller une embouchure de tuyau de collecte de liquide (31). Un coefficient de frottement statique entre le bouchon de tuyau (33) et la paroi périphérique interne du cylindre externe (1) est µ1, un coefficient de frottement statique entre le bouchon de tuyau (33) et l'embouchure de tuyau de collecte de liquide (31) est µ2, et les coefficients satisfont à ce que µ1 est inférieur à µ2 ; ou le bouchon de tuyau (33) est espacé de la paroi périphérique interne du cylindre externe (1). Selon le dispositif de collecte d'humeur aqueuse (100), la vitesse de drainage de l'humeur aqueuse pendant la ponction peut être contrôlée, et la contamination de l'humeur aqueuse une fois la collecte achevée et les déchets provoqués par le transfert de l'humeur aqueuse peuvent être évités, et le dispositif présente une sécurité et une fiabilité élevées.
PCT/CN2019/094383 2019-07-02 2019-07-02 Dispositif de collecte d'humeur aqueuse WO2021000255A1 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
PCT/CN2019/094383 WO2021000255A1 (fr) 2019-07-02 2019-07-02 Dispositif de collecte d'humeur aqueuse
PCT/CN2019/110062 WO2021000440A1 (fr) 2019-07-02 2019-10-09 Dispositif de collecte d'humeur aqueuse et procédé de collecte d'humeur aqueuse
US17/624,393 US20220354468A1 (en) 2019-07-02 2020-06-18 Reagent holder, testing apparatus assembly, aqueous humor collection device and aqueous humor collection method
JP2021577950A JP7337967B2 (ja) 2019-07-02 2020-06-18 試薬ホルダー、検出装置アセンブリー、房水採取装置及び房水採取方法
PCT/CN2020/096860 WO2021000743A1 (fr) 2019-07-02 2020-06-18 Support de réactif, ensemble appareil de test, dispositif de collecte d'humeur aqueuse et procédé de collecte d'humeur aqueuse
EP20834808.6A EP3995215A4 (fr) 2019-07-02 2020-06-18 Support de réactif, ensemble appareil de test, dispositif de collecte d'humeur aqueuse et procédé de collecte d'humeur aqueuse
IL289549A IL289549A (en) 2019-07-02 2022-01-02 Reagent holder, test device assembly, aqueous tissue fluid collection device and method for aqueous tissue fluid collection
JP2023134836A JP2023164441A (ja) 2019-07-02 2023-08-22 試薬ホルダー、検出装置アセンブリー、房水採取装置及び房水採取方法

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PCT/CN2019/094383 WO2021000255A1 (fr) 2019-07-02 2019-07-02 Dispositif de collecte d'humeur aqueuse

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WO2021000255A1 true WO2021000255A1 (fr) 2021-01-07

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PCT/CN2019/094383 WO2021000255A1 (fr) 2019-07-02 2019-07-02 Dispositif de collecte d'humeur aqueuse

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07204180A (ja) * 1994-01-21 1995-08-08 Nissho Corp 採血管ホルダー
JPH11290298A (ja) * 1998-04-10 1999-10-26 Sekisui Chem Co Ltd 採血管ホルダー
JP2007111215A (ja) * 2005-10-20 2007-05-10 Sekisui Chem Co Ltd 採血ホルダー
EP2319413A1 (fr) * 2007-12-14 2011-05-11 Tyco Healthcare Group LP Dispositif de prise de sang doté d'une structure de retenue de tube
CN204050005U (zh) * 2014-09-09 2014-12-31 赵潺 一次性负压前房穿刺针
US20150335486A1 (en) * 2012-01-12 2015-11-26 Innfocus, Inc. Method, Surgical Kit and Device for Treating Glaucoma

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07204180A (ja) * 1994-01-21 1995-08-08 Nissho Corp 採血管ホルダー
JPH11290298A (ja) * 1998-04-10 1999-10-26 Sekisui Chem Co Ltd 採血管ホルダー
JP2007111215A (ja) * 2005-10-20 2007-05-10 Sekisui Chem Co Ltd 採血ホルダー
EP2319413A1 (fr) * 2007-12-14 2011-05-11 Tyco Healthcare Group LP Dispositif de prise de sang doté d'une structure de retenue de tube
US20150335486A1 (en) * 2012-01-12 2015-11-26 Innfocus, Inc. Method, Surgical Kit and Device for Treating Glaucoma
CN204050005U (zh) * 2014-09-09 2014-12-31 赵潺 一次性负压前房穿刺针

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