WO2019056725A1

WO2019056725A1 - Preservative-free mask

Info

Publication number: WO2019056725A1
Application number: PCT/CN2018/080780
Authority: WO
Inventors: 伍华兵; 梁瑶; 詹凯; 赵应香; 喻祺
Original assignee: 中聚科技股份有限公司
Priority date: 2017-09-24
Filing date: 2018-03-28
Publication date: 2019-03-28
Also published as: CN107648060A

Abstract

A preservative-free mask, composed of the following components in percentage by weight: an electrolyte: 10％-60％; a humectant: 0.01％-50％; a thickener: 0.01％-5％; an essence: 0.01％-2％; a pigment: 0％-2％; a pH regulator: 0％-2％; a chelating agent: 0％-2％; functional components: 0.01％-60％; and the balance being water.

Description

a preservative-free mask

Technical field

The invention relates to a preservative-free mask, belonging to the technical field of cosmetics.

Background technique

Because the mask can not be completely sterile during production and packaging, and the mask is rich in nutrients, it provides a good hotbed for bacterial growth. Therefore, preservatives must be added to the mask, otherwise it is easy to breed due to bacteria. And cause deterioration. Deteriorated products often have pungent or unpleasant odors, or cause allergies and irritation to consumers. However, more and more scientific experiments have confirmed that preservatives in masks are prone to allergies and contact dermatitis, and some preservatives can also induce breast cancer. Therefore, with the increase in consumption and consumer awareness, no anti-corrosion has become An important trend for consumers to choose a mask.

In the presence of high concentration electrolytes, the osmotic pressure of intracellular protein solutions of microorganisms and bacteria is much smaller than the osmotic pressure of extracellular electrolytes. At this time, the water molecules in the cells of microorganisms and bacteria pass through the cell membrane from osmotic pressure. The smaller one penetrates into the side with a large osmotic pressure, that is, it penetrates from the cell membrane to the outside of the cell membrane, and the cells are thus dehydrated and killed. Thus, a high concentration of electrolyte has an antiseptic effect.

However, high concentrations of electrolytes can destabilize the mask formulation, making the mask very easy to stratify. Therefore, the stability of the formulation needs to be carefully evaluated during formulation development. Only when the right raw materials are selected for compounding can the stability meet the national standard.

Masks containing high concentrations of electrolytes and stability to national standards can effectively prevent the growth of microorganisms and bacteria, eliminating the need to add preservatives and completely eliminating the negative effects of preservatives. At the same time, these electrolytes can also gently kill facial bacteria, and have good effects on skin inflammation and acne.

technical problem

It is an object of the present invention to provide a preservative-free mask.

Technical solution

Technical Solution of the Invention: A preservative-free mask formulation consists of the following components by weight:

Electrolyte 10% to 70%,

Humectant 0.01% to 50%,

Thickener 0.01% to 5%,

Flavor 0.01% to 2%,

Pigment 0% to 2%,

pH regulator 0~2%,

Chelating agent 0% to 2%,

Functional ingredients 0.01% to 60%,

The balance is water.

Further, the electrolyte is an ionic compound that is easily soluble in water.

Further, the humectant comprises glycerin, propylene glycol, butanediol, pentanediol, hexanediol, ethylhexylglycerol, sorbitol, xylitol, hyaluronic acid, white fungus hyaluronic acid, hyaluronic acid, collagen One or more of protein, trehalose, ceramide, polyethylene glycol, polyglycerol, polyamino acid, urea, sodium lactate, pyrrolidone carboxylic acid.

Further, the thickener comprises one of a cellulose thickener, an acrylic acid and a methacrylic acid derivative, a starch, a guar gum and a derivative thereof, a vegetable gum, and a polyoxyethylene. Kind or more.

Further, the pH adjusting agent is one of an aqueous solution of citric acid, citrate, lactic acid, sodium lactate, hydrochloric acid, sulfuric acid, disodium hydrogen phosphate, sodium dihydrogen phosphate, sodium hydroxide, potassium hydroxide or triethanolamine. Kind or more.

Further, the chelating agent comprises one or more of ethylenediaminetetraacetic acid and a salt thereof, diethylenetriaminepentaacetic acid and a salt thereof, and aminotriacetic acid.

Further, the functional component comprises one or more of plant extracts, animal extracts, oils and derivatives thereof, vitamins and derivatives thereof, phospholipids, amino acids, polypeptides, proteins and derivatives thereof.

Beneficial effect

The invention has the beneficial effects that the preservative is replaced by a high-concentration electrolyte, and the negative effects on the facial skin and the human body caused by the mask with the added preservative are prevented, and the skin inflammation and the acne of the face are also Very good effect.

BEST MODE FOR CARRYING OUT THE INVENTION

The present invention will be described in further detail with reference to the embodiments, but the embodiments of the present invention are not limited thereto.

Example 1:

A moisturizing mask without preservatives consisting of the following components:

Sodium sulfate 25%,

Potassium sulfate 5%,

Glycerin 10%,

Propylene glycol 2%

Hyaluronic acid 0.5%,

Hydroxyethyl cellulose 0.5%,

Fragrance 0.1%,

Citric acid 0.05%,

EDTA disodium salt 0.1%,

Tremella extract 1%,

The balance is water.

Embodiments of the invention

Example 2:

A whitening mask without preservatives consisting of the following components:

Potassium chloride 20%,

Sodium chloride 10%,

Glycerin 10%,

Propylene glycol 2%,

Hydroxyethyl cellulose 0.5%,

Fragrance 0.12%,

Citric acid 0.03%,

EDTA disodium salt 0.1%,

Ethyl vitamin C 1%,

White peony extract 1%,

Centella asiatica extract 0.5%,

The balance is water.

Example 3:

A acne mask without preservatives consisting of the following components:

Sodium chloride 35%,

Potassium sulfate 10%,

Glycerin 8%,

Propylene glycol 5%,

Hydroxyethyl cellulose 0.5%,

Fragrance 0.1%,

EDTA disodium salt 0.1%,

Dipotassium glycyrrhizinate 1%,

Allantoin 1%,

Salicylic acid 1%

Tangerine extract 0.5%,

The balance is water.

In order to verify the stability of the mask formulation, stability tests were carried out on Examples 1, 2 and 3 using the stability test method in QB/T 2872-2007. The results are shown in Table 1.

Table 1

The test results of Table 1 illustrate that the stability of Examples 1, 2 and 3 meets the requirements of national standards.

In order to verify the antiseptic efficacy of high-concentration electrolytes, we performed microbial preservative efficacy tests on Examples 1, 2, and 3 using USP 32P51. The results are shown in Table 2.

Table 2

The US Pharmacopoeia USP32<51> is judged as follows: 1) The logarithmic reduction of the number of bacteria from the initial to 14 days cannot be less than 2.0, and the number of bacteria cannot be increased from 14 days to 28 days; 2) mold and yeast The total number of molds and yeasts could not be increased from the initial to 14 days and 28 days.

According to the judging standard of the United States Pharmacopoeia USP32<51>, the experimental results in Table 1 confirm that a high concentration of electrolyte can effectively kill and inhibit various types of bacteria in Example 1, Example 2 and Example 3, which can

No preservatives need to be added in Example 1, Example 2 and Example 3.

Industrial applicability

Type the industrial usability description paragraph here.

Sequence table free content

Type the sequence table free content description paragraph here.

Claims

A preservative-free mask characterized by weight percent consisting of the following components:

Electrolyte 10% to 70%,

Moisturizer 0.01% to 50%,

Thickener 0.01% to 5%,

Flavor 0.01% to 2%,

Pigment 0% to 2%,

pH regulator 0~2%,

Chelating agent 0% to 2%,

Functional ingredients 0.01% to 60%,

The balance is water.
A preservative-free mask according to claim 1, wherein the electrolyte is a water-soluble ionic compound.
The preservative-free mask according to claim 1, wherein the humectant comprises glycerin, propylene glycol, butylene glycol, pentanediol, hexanediol, ethylhexylglycerol, sorbitol, One or more of xylitol, hyaluronic acid, white fungus hyaluronic acid, hyaluronic acid, collagen, trehalose, ceramide, polyethylene glycol, polyglycerol, polyamino acid, urea, sodium lactate, pyrrolidone carboxylic acid.
The preservative-free mask according to claim 1, wherein the thickener comprises a cellulose thickener, acrylic acid and methacrylic acid derivatives, starch, guar gum and One or more of a derivative, a vegetable gum, or a polyoxyethylene.
The preservative-free mask according to claim 1, wherein the pH adjuster is citric acid, citrate, lactic acid, sodium lactate, hydrochloric acid, sulfuric acid, disodium hydrogen phosphate, sodium dihydrogen phosphate. One or more of an aqueous solution of sodium hydroxide, potassium hydroxide or triethanolamine.
The preservative-free mask according to claim 1, wherein the chelating agent comprises ethylenediaminetetraacetic acid and a salt thereof, diethylenetriaminepentaacetic acid and a salt thereof, and aminotriacetic acid. One or more.
The preservative-free mask according to claim 1, wherein the functional ingredient comprises plant extract, animal extract, oil and its derivatives, vitamins and derivatives thereof, phospholipids, amino acids, One or more of a polypeptide, a protein, and a derivative thereof.