CN105726457A - Oligopeptide mask essence - Google Patents

Oligopeptide mask essence Download PDF

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Publication number
CN105726457A
CN105726457A CN201610172308.3A CN201610172308A CN105726457A CN 105726457 A CN105726457 A CN 105726457A CN 201610172308 A CN201610172308 A CN 201610172308A CN 105726457 A CN105726457 A CN 105726457A
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CN
China
Prior art keywords
parts
oligopeptide
essence
extract
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610172308.3A
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Chinese (zh)
Inventor
王善恒
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yantai Huaxin Biopharmaceutical Technology Co Ltd
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Yantai Huaxin Biopharmaceutical Technology Co Ltd
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Application filed by Yantai Huaxin Biopharmaceutical Technology Co Ltd filed Critical Yantai Huaxin Biopharmaceutical Technology Co Ltd
Priority to CN201610172308.3A priority Critical patent/CN105726457A/en
Publication of CN105726457A publication Critical patent/CN105726457A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37Esters of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/88Polyamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cosmetics (AREA)

Abstract

The invention relates to an oligopeptide mask essence, which is prepared from the following components in parts by weight: 0.05-0.5 part of oligopeptide-1, 0.5-2.0 parts of polyglutamic acid, 1.0-5.0 parts of an avena sativa kernel extract, 1.0-5.0 parts of tremella polysaccharide, 0.1-1.0 part of a bacillus/soybean fermented product extract, 1.0-5.0 parts of beta-glucosan, 0.1-1.0 part of folic acid, 0.05-0.5 part of hyaluronic acid, 1.0-5.0 parts of an aloe extract, 5-15 parts of glycerinum, 0.05-0.1 part of methylparaben, 1.0-5.0 parts of 1,2-pentanediol, 0.5-2.0 parts of phenoxyethanol, 0.01-0.2 part of essence and 30-40 parts of deionized water. Through reasonable coordination of oligopeptide active matters and other components, a pure micromolecular structure which is similar to a cell sap in nutrient is prepared; the oligopeptide mask essence has five-in-one effects of smoothing, modifying, brightening, whitening and tightening the skin; and the prescription is comprehensive in function and meets all requirements of the skin on the mask.

Description

A kind of oligopeptide facial mask essence
Technical field
The present invention relates to a kind of oligopeptide facial mask essence.
Background technology
In prior art, facial film form is varied, and facial film kind is the most varied.But the most existing In film, mainly moisture-keeping efficacy or mainly white-skinned face function etc., function singleness.
Therefore, it is necessary to propose effectively can supplement the technical scheme of facial various demand, in solution simultaneously State problem.
Summary of the invention
The present invention is directed to above-mentioned the deficiencies in the prior art, it is provided that a kind of multi-functional oligopeptide facial mask essence.
The technical scheme is that
A kind of oligopeptide facial mask essence, including following ingredients weight parts: oligopeptide-10.05~0.5 part, poly- Glutamic acid 0.5~2.0 parts, oat kernel extract 1.0~5.0 parts, tremella polysaccharide 1.0~5.0 parts, Bacillus cereus/fermented soybean product extract 0.1~1.0 parts, beta glucan 1.0~5.0 parts, leaf Acid 0.1~1.0 part, hyaluronic acid 0.05~0.5 part, Aloe extract 1.0~5.0 parts, glycerol 5~ 15 parts, methyl hydroxybenzoate 0.05~0.1 part, 1,2-pentanediol 1.0~5.0 parts, phenoxyethanol 0.5~ 0.2 part, essence 0.01~0.2 part, deionized water 30~40 parts.
Preferably, oligopeptide facial mask essence includes following ingredients weight parts: oligopeptide-10.5 parts, polyglutamic Acid 1.0 parts, oat kernel extract 5.0 parts, tremella polysaccharide 2.0 parts, bacillus cereus/fermented soybean produce Thing extract 5.0 parts, beta glucan 2.0 parts, 0.5 part of folic acid, hyaluronic acid 0.1 part, Aloe Extract 2.0 parts, glycerol 10.0 parts, methyl hydroxybenzoate 0.05 part, 1,2-pentanediol 1.0 parts, benzene oxygen Ethanol 0.5 part, 0.01 part of essence, deionized water 30 parts.
Beneficial effect: reasonably combined by oligopeptide active matter and other compositions, makes and Cell sap nutrition Similar consummate small molecule structure, skin is played profit, repair, effect that five effects bright, white, tight are unified, Inventive formulation complete function, meets the skin whole demands to facial film.
Detailed description of the invention
The present invention provides a kind of oligopeptide facial mask essence, extracts including oligopeptide-1, polyglutamic acid, oat kernel Thing, tremella polysaccharide, bacillus cereus/fermented soybean product extract, beta glucan, folic acid, hyalomitome Acid.
The use of mentioned component, is important to invention facial mask essence.
Applying oligopeptide-1 in above-mentioned oligopeptide facial mask essence, it is epidermal growth active factors, and it has Promote the biological effect of skin epidermal cells growth metabolism.
Applying polyglutamic acid in above-mentioned oligopeptide facial mask essence, it is efficient moisture-retention agent, simultaneously polyglutamic Glutamic acid after acid degradation is nontoxic, biodegradable, high-end product nutritious to skin.
Applying oat kernel extract in above-mentioned oligopeptide facial mask essence, it contains antioxidant, can be effective Remove free radical, reduce the injury of radical pair Skin Cell, reduce wrinkle and occur, desalinate mottle;Tool There is irritation characteristic, especially can effectively remove and be irradiated, by ultraviolet, the general red phenomenon of skin table caused, to allergy Property skin has good nursing role.
Applying tremella polysaccharide in above-mentioned oligopeptide facial mask essence, it has defying age, antioxidation, Gao Bao Wet function, its moisture-retaining capacity is 1000 times of own wt.
Applying bacillus cereus/fermented soybean product extract in above-mentioned oligopeptide facial mask essence, it possesses Good bacteriostasis it is also equipped with while high moisture-keeping function.
Applying beta glucan in above-mentioned oligopeptide facial mask essence, it can improve the immunity of skin self Power, has the effect removing free radical, assists damaged tissues to add quick-recovery and produces cytokines, especially in sensitivity Skin reparation aspect has the biological activity of uniqueness.
Applying folic acid in above-mentioned oligopeptide facial mask essence, it possesses effect of activation skin care.
Applying hyaluronic acid in above-mentioned oligopeptide facial mask essence, it possesses effect of water conservation.
For a better understanding of the present invention, it is illustrated below by specific embodiment.
Embodiment 1
A kind of oligopeptide facial mask essence, including following ingredients weight parts: oligopeptide-10.5 parts, polyglutamic acid 1.0 parts, oat kernel extract 5.0 parts, tremella polysaccharide 2.0 parts, bacillus cereus/fermented soybean product extract Thing 5.0 parts, beta glucan 2.0 parts, 0.5 part of folic acid, hyaluronic acid 0.1 part, Aloe extract 2.0 parts, Glycerol 10.0 parts, methyl hydroxybenzoate 0.05 part, 1,2-pentanediol 1.0 parts, phenoxyethanol 0.5 part, essence 0.01 Part, deionized water 30 parts.
Oligopeptide facial mask essence of the present invention, in the preparation, uses facial mask essence routine preparation means. Preferably, in the preparation, by instant component when-2 to-1 degrees Celsius, it is simultaneously introduced in container, mixed Conjunction stirs.
The present invention can summarize with other the concrete form without prejudice to the spirit or essential characteristics of the present invention. Therefore, no matter from the point of view of which point, the embodiment above of the present invention all can only be considered the present invention's Illustrating and can not limit the present invention, claims indicate the scope of the present invention, and above-mentioned explanation is also Do not point out the scope of the present invention, therefore, in the implication suitable with claims of the present invention and scope Any change, be all considered as being included in the range of claims of the present invention.

Claims (2)

1. an oligopeptide facial mask essence, it is characterised in that include following ingredients weight parts: oligopeptide -10.05~0.5 parts, polyglutamic acid 0.5~2.0 parts, oat kernel extract 1.0~5.0 parts, Tremella Polysaccharide 1.0~5.0 parts, bacillus cereus/fermented soybean product extract 0.1~1.0 parts, β-Portugal gather Sugar 1.0~5.0 parts, folic acid 0.1~1.0 parts, hyaluronic acid 0.05~0.5 part, Aloe extract 1.0~ 5.0 parts, glycerol 5~15 parts, methyl hydroxybenzoate 0.05~0.1 part, 1,2-pentanediol 1.0~5.0 parts, Phenoxyethanol 0.5~0.2 part, essence 0.01~0.2 part, deionized water 30~40 parts.
2. oligopeptide facial mask essence as claimed in claim 1, it is characterised in that include following component Weight portion: oligopeptide-10.5 parts, polyglutamic acid 1.0 parts, oat kernel extract 5.0 parts, tremella polysaccharide 2.0 parts, bacillus cereus/fermented soybean product extract 5.0 parts, beta glucan 2.0 parts, folic acid 0.5 Part, hyaluronic acid 0.1 part, Aloe extract 2.0 parts, glycerol 10.0 parts, methyl hydroxybenzoate 0.05 part, 1,2-pentanediol 1.0 parts, phenoxyethanol 0.5 part, 0.01 part of essence, deionized water 30 parts.
CN201610172308.3A 2016-03-24 2016-03-24 Oligopeptide mask essence Pending CN105726457A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610172308.3A CN105726457A (en) 2016-03-24 2016-03-24 Oligopeptide mask essence

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610172308.3A CN105726457A (en) 2016-03-24 2016-03-24 Oligopeptide mask essence

Publications (1)

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CN105726457A true CN105726457A (en) 2016-07-06

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Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106924073A (en) * 2017-05-09 2017-07-07 南通千竹电子科技有限公司 A kind of replenishing water and preserving moisture facial mask and preparation method thereof
CN107362059A (en) * 2017-08-14 2017-11-21 泉州亚林新材料科技有限公司 A kind of moisture saver mask liquid containing oligopeptides and preparation method thereof
CN107375180A (en) * 2017-08-11 2017-11-24 北京斯利安药业有限公司 A kind of composite skin care product, facial mask and preparation method thereof
CN108186455A (en) * 2018-03-07 2018-06-22 孙伟 A kind of facial mask essence containing Succinum extract
CN108619078A (en) * 2018-08-20 2018-10-09 广州无添加主义化妆品有限公司 A kind of whitening skin lightening facial mask and preparation method thereof
CN109303735A (en) * 2018-12-21 2019-02-05 广州欧盛化妆品有限公司 A kind of skin whitening, moisturizing frost and preparation method
CN109431879A (en) * 2018-11-22 2019-03-08 天津市天大天福生物技术有限公司 The application and production technology of a kind of tremella extract in skin care item
CN109568246A (en) * 2018-12-24 2019-04-05 广州欧盛化妆品有限公司 A kind of crease-resistant moisturiser and preparation method thereof
WO2019075801A1 (en) * 2017-10-19 2019-04-25 广州无添加主义化妆品有限公司 Skincare mask and preparation method therefor
CN110368416A (en) * 2019-08-08 2019-10-25 武汉易瑞生物医药有限公司 Immune activation peptide adjusts antibacterial emulsifiable paste
CN110731908A (en) * 2018-07-19 2020-01-31 广州达人研选生物科技有限公司 facial mask set for light diet and use method thereof
CN111789807A (en) * 2020-08-25 2020-10-20 浙江伊瑟奇医药科技有限公司 Repair liquid for plant extract and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104814919A (en) * 2015-05-13 2015-08-05 朱敏 Moisturizing anti-wrinkle mask solution, manufacturing method and moisturizing anti-wrinkle mask

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104814919A (en) * 2015-05-13 2015-08-05 朱敏 Moisturizing anti-wrinkle mask solution, manufacturing method and moisturizing anti-wrinkle mask

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
天津市科技史志编修办公室: "《天津科技年鉴》", 30 November 2007, 方志出版社 *
王昌涛: "《化妆品植物添加剂的开发与应用》", 30 April 2013, 中国轻工业出版社 *

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106924073A (en) * 2017-05-09 2017-07-07 南通千竹电子科技有限公司 A kind of replenishing water and preserving moisture facial mask and preparation method thereof
CN107375180A (en) * 2017-08-11 2017-11-24 北京斯利安药业有限公司 A kind of composite skin care product, facial mask and preparation method thereof
CN107375180B (en) * 2017-08-11 2020-10-16 北京斯利安药业有限公司 Skin care product composition, facial mask and preparation method of facial mask
CN107362059A (en) * 2017-08-14 2017-11-21 泉州亚林新材料科技有限公司 A kind of moisture saver mask liquid containing oligopeptides and preparation method thereof
WO2019075801A1 (en) * 2017-10-19 2019-04-25 广州无添加主义化妆品有限公司 Skincare mask and preparation method therefor
CN108186455A (en) * 2018-03-07 2018-06-22 孙伟 A kind of facial mask essence containing Succinum extract
CN110731908A (en) * 2018-07-19 2020-01-31 广州达人研选生物科技有限公司 facial mask set for light diet and use method thereof
CN108619078A (en) * 2018-08-20 2018-10-09 广州无添加主义化妆品有限公司 A kind of whitening skin lightening facial mask and preparation method thereof
CN109431879A (en) * 2018-11-22 2019-03-08 天津市天大天福生物技术有限公司 The application and production technology of a kind of tremella extract in skin care item
CN109303735A (en) * 2018-12-21 2019-02-05 广州欧盛化妆品有限公司 A kind of skin whitening, moisturizing frost and preparation method
CN109568246A (en) * 2018-12-24 2019-04-05 广州欧盛化妆品有限公司 A kind of crease-resistant moisturiser and preparation method thereof
CN110368416A (en) * 2019-08-08 2019-10-25 武汉易瑞生物医药有限公司 Immune activation peptide adjusts antibacterial emulsifiable paste
CN111789807A (en) * 2020-08-25 2020-10-20 浙江伊瑟奇医药科技有限公司 Repair liquid for plant extract and preparation method thereof

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