CN111821226A - Plant-derived telomerase composition and novel application thereof in cosmetics - Google Patents
Plant-derived telomerase composition and novel application thereof in cosmetics Download PDFInfo
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- CN111821226A CN111821226A CN201910301489.9A CN201910301489A CN111821226A CN 111821226 A CN111821226 A CN 111821226A CN 201910301489 A CN201910301489 A CN 201910301489A CN 111821226 A CN111821226 A CN 111821226A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/645—Proteins of vegetable origin; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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Abstract
The invention discloses a plant-derived telomerase composition and application thereof in cosmetics. The plant-derived telomerase composition is prepared by respectively hydrolyzing soybean protein, yeast protein and oat protein, and compounding oat peptide, dog rose fruit extract, tea extract, tremella extract and yeast fermentation product extract, and can promote blood circulation of facial skin, activate aged epidermal cells, plump facial skin, repair fine lines, relieve skin water deficiency, improve skin redness and swelling, brighten skin color, and care skin. The plant-derived telomerase composition can be further prepared into forms of aqua, emulsion, gel, cream and the like, and is used for developing and utilizing anti-aging repair series products.
Description
The technical field is as follows: the invention belongs to the technical field of daily chemicals, and particularly relates to a plant-derived telomerase composition and a novel application thereof in cosmetics.
Background art:
chromosome telomeres are known as the division clock of cells, and along with the continuous division of cells, the chromosome breakage is continuously shortened, and the division of cells can be gradually slowed until stopping, which is the root cause of cell aging. Telomerase active component, telomerase, extracted from natural plant can prolong the life of telomere and activate cell dividing structural unit to realize cell regeneration.
Can repair damaged chromosome telomeres, improve the reconstruction capability of ossein, elastic fiber and hyaluronic acid, and achieve the effects of removing freckles, wrinkles and skin elasticity.
The hydrolyzed soybean protein, hydrolyzed yeast protein, hydrolyzed oat protein and hydrolyzed royal jelly protein belong to plant-derived telomerase, and have the effects of repairing skin and delaying aging.
The hydrolyzed soybean protein has high moisture keeping effect, and can be used as humectant and skin conditioner. The hydrolyzed soy protein is helpful for inducing skin to generate hyaluronic acid, commonly called hyaluronic acid, and is an ideal natural moisturizing factor and a natural component for promoting skin tissue metabolism and maintenance functions in female bodies. When the content of hyaluronic acid in human skin is gradually reduced day by day, the skin is matured and the aging process is occurring. The hydrolyzed soybean protein can induce the original role and increase the concentration of hyaluronic acid in skin, thereby achieving the effect of high-efficiency moisture retention.
The hydrolyzed yeast protein has slightly lower water and moisture absorption capacity, oil absorption capacity, foamability and emulsification assisting capacity. The aqueous solution has slightly high viscosity, can be rapidly absorbed by skin, has no greasy feeling, and is suitable for use as skin care raw material of cosmetic.
The hydrolyzed oat protein can increase the content of cortical collagen, maintain the structural integrity of skin, keep the elasticity of skin, and has the functions of resisting aging and wrinkle; the hydrolyzed oat protein has certain surface activity, and has emulsification, foaming and foam stabilizing effects.
The hydrolyzed royal jelly protein has high anti-irritation and collagen promoting effects. It has effects in increasing collagen content of skin, relieving skin irritation, preventing wrinkle and flabbiness, resisting oxidation, scavenging free radicals, and preventing skin aging.
The oat peptide has strong protease activity inhibition and antioxidant effect; meanwhile, the skin care product also has the function of permeation and helps the skin to better absorb other nutrient substances; meanwhile, the skin is provided with nutrition, the skin is conditioned, the moisture is effectively preserved, and the skin roughness is reduced.
The fructus Rosae Davuricae extract has effect in inhibiting elastase, resisting wrinkle, and resisting aging, and has DOD-like activity.
The tea extract has multiple functional components such as tea polyphenol and catechin. The tea extract has an inhibiting effect on caspase, the caspase is a core molecule of apoptosis, the inhibition of the caspase means prolonging the life of cells, and the tea extract is an anti-wrinkle and anti-aging additive for cosmetics by combining the anti-oxygen property of the tea extract, the elimination of free radicals of a human body, the inhibition of two kinds of metalloproteases and the inhibition of collagenase.
The tremella extract has the effects of inhibiting the activity of collagenase and promoting the generation of a plurality of biochemical components, and has the effects of activating skin and resisting wrinkles; the extract has good moisture keeping effect, and can be used as humectant; it also has certain effect in inhibiting skin allergy, and can be used as soothing and antiallergic agent.
The secondary fission yeast fermentation product extract contains nutrients such as amino acids and vitamins, stimulates cell renewal, prolongs cell life, and can promote wound healing and prevent aging.
The invention content is as follows:
the invention aims to provide a plant-derived telomerase composition and a novel application thereof in cosmetics, wherein plant-derived telomerase and natural plant extracts or fermentation filtrates are matched in different proportions to be used as active ingredients to be applied to the cosmetics, so that the effects of moisturizing, whitening, wrinkle removal and the like can be realized, the blood circulation of facial skin can be promoted, aged epidermal cells can be activated, the facial skin can be plumped, fine wrinkles can be repaired, meanwhile, the skin hydropenia can be relieved, the red and swollen symptom of the skin can be improved, the skin color can be brightened, and the skin can be moisturized and beautified. Compared with cosmetics which only use chemical substances as active ingredients, the cosmetics containing the plant-derived telomerase composition have the advantages of more comprehensive efficacy, mild property, no toxic or side effect, and simple and reliable process.
A plant-derived telomerase composition is prepared from hydrolyzed soybean protein, hydrolyzed yeast protein, hydrolyzed oat protein, hydrolyzed royal jelly protein, oat peptide, fructus Rosae Davuricae extract, folium Camelliae sinensis extract, Tremella extract, and yeast fermentation product extract. The mass fraction of each raw material is as follows:
preferably, the mass fractions of the raw materials are as follows:
the plant-derived telomerase composition can be added into cosmetics.
The invention provides a preparation method for adding a plant-derived telomerase composition into cosmetics, which comprises the following steps:
(1) heating the oily components to 130 ℃ at the rotation speed of 600-900rpm for 5-15 min;
(2) cooling to 60-90 deg.C, adding plant source telomerase composition and antiseptic, stirring at 600-;
(3) after cooling, the product is shaped into a predetermined cosmetic form.
Preferably, the preparation method of adding the plant-derived telomerase composition into cosmetics comprises the following steps:
(1) heating the oily component to 105 deg.C, stirring at 750rpm for 5 min;
(2) cooling to 67 deg.C, adding plant-derived telomerase composition and antiseptic, and stirring at 775rpm for 8 min;
(3) after cooling, the product is shaped into a predetermined cosmetic form.
The content of the plant-derived telomerase composition is 1-15% (mass fraction) based on the total weight of the cosmetic. Preferably, the content of the plant-derived telomerase composition for cosmetics is 10% (mass fraction).
The cosmetic containing the plant-derived telomerase composition obtained by the method is mild and non-irritant, and has the effects of moisturizing, whitening, removing wrinkles and the like.
Example 1A plant-derived telomerase composition and novel use thereof in cosmetics
A plant-derived telomerase composition comprises the following raw materials in parts by mass:
adding the plant-derived telomerase composition into cosmetics, wherein the steps are as follows:
(1) heating the oily component to 110 deg.C, stirring at 750rpm for 5 min;
(2) cooling to 75 deg.C, adding plant-derived telomerase composition and antiseptic, and stirring at 775rpm for 8 min;
(3) after cooling, the product is shaped into a predetermined cosmetic form.
The content of the plant-derived telomerase composition used in cosmetics is 1% (mass fraction) based on the total weight of the cosmetics.
The product prepared by the method is No. 1 product.
Example 2A plant-derived telomerase composition and novel use thereof in cosmetics
A plant-derived telomerase composition comprises the following raw materials in parts by mass:
adding the plant-derived telomerase composition into cosmetics, wherein the steps are as follows:
(1) heating the oily component to 100 deg.C, stirring at 900rpm for 10 min;
(2) cooling to 60 deg.C, adding plant-derived telomerase composition and antiseptic, and stirring at 850rpm for 15 min;
(3) after cooling, the product is shaped into a predetermined cosmetic form.
The content of the plant-derived telomerase composition used in cosmetics is 5% (mass fraction) based on the total weight of the cosmetics.
The product obtained by the method is a No. 2 product.
Example 3A plant-derived telomerase composition and novel use thereof in cosmetics
A plant-derived telomerase composition comprises the following raw materials in parts by mass:
adding the plant-derived telomerase composition into cosmetics, wherein the steps are as follows:
(1) heating the oily component to 105 deg.C, stirring at 750rpm for 5 min;
(2) cooling to 67 deg.C, adding plant-derived telomerase composition and antiseptic, and stirring at 775rpm for 8 min;
(3) after cooling, the product is shaped into a predetermined cosmetic form.
The content of the plant-derived telomerase composition used in cosmetics is 10% (mass fraction) based on the total weight of the cosmetics.
The product obtained by the method is a product No. 3.
Example 4A plant-derived telomerase composition and novel use thereof in cosmetics
A plant-derived telomerase composition comprises the following raw materials in parts by mass:
adding the plant-derived telomerase composition into cosmetics, wherein the steps are as follows:
(1) heating the oily component to 110 deg.C, stirring at 800rpm for 7 min;
(2) cooling to 80 deg.C, adding plant-derived telomerase composition and antiseptic, and stirring at 700rpm for 10 min;
(3) after cooling, the product is shaped into a predetermined cosmetic form.
The content of the plant-derived telomerase composition used in cosmetics is 10% (mass fraction) based on the total weight of the cosmetics.
The product obtained by the method is a No. 4 product.
Comparative example 1 wrinkle-improving ability of plant-derived telomerase composition
TABLE 1 collagenase inhibition
| Content (ppm) of plant-derived telomerase composition | Inhibition ratio (%) |
| 100 | 5.1 |
| 200 | 11.5 |
| 300 | 40.7 |
| 400 | 36.2 |
It can be seen from table 1 that the plant-derived telomerase composition has a good ability to inhibit collagenase activity, and can achieve the effects of improving skin elasticity and inhibiting wrinkle formation by inhibiting collagenase activity.
Comparative example 2 moisturizing ability of plant-derived telomerase composition
TABLE 2 skin moisturizing ability test
| Skin moisturizing ability test | Skin moisturizing ability (A.U.) |
| Unused telomerase compositions | 40 |
| Product 1 | 63 |
| Product 2 | 85 |
| Product 3 | 90 |
| Product 4 | 83 |
TABLE 3 skin dehydration test
| Skin Water loss test | Loss of water (g/h/m) from the skin2) |
| Unused telomerase compositions | 38 |
| Product 1 | 20 |
| Product 2 | 16 |
| Product 3 | 8 |
| Product 4 | 13 |
As shown in tables 2 and 3, it can be seen from the test experiments of skin moisturizing ability and skin water loss that the plant-derived telomerase composition has a high moisturizing effect, can effectively reduce the loss of epidermal water, and enables the skin to efficiently resist dryness.
As can be seen from the comparison of table 2 and table 3, the plant-derived telomerase composition has a good moisturizing effect.
Claims (7)
1. A plant-derived telomerase composition is prepared from hydrolyzed soybean protein, hydrolyzed yeast protein, hydrolyzed oat protein, hydrolyzed royal jelly protein, oat peptide, fructus Rosae Davuricae extract, folium Camelliae sinensis extract, Tremella extract, and yeast fermentation product extract. The mass fraction of each raw material is as follows:
2. the plant extract composition according to claim 1, wherein the mass fraction of each raw material is:
3. a method for preparing a cosmetic comprising the plant-derived telomerase composition of claim 1 or 2, which comprises the steps of:
(1) heating the oily components to 130 ℃ at the rotation speed of 600-900rpm for 5-15 min;
(2) cooling to 60-90 deg.C, adding plant source telomerase composition and antiseptic, stirring at 600-;
(3) after cooling, the product is shaped into a predetermined cosmetic form.
4. A method according to claim 3, characterized by the steps of:
(1) heating the oily component to 105 deg.C, stirring at 750rpm for 5 min;
(2) cooling to 67 deg.C, adding plant-derived telomerase composition and antiseptic, and stirring at 775rpm for 8 min;
(3) after cooling, the product is shaped into a predetermined cosmetic form.
5. A cosmetic comprising the plant-derived telomerase composition as claimed in any of claims 1 to 2.
6. The cosmetic according to claim 5, wherein the plant-derived telomerase composition is contained in an amount of 1 to 15% (mass fraction) based on the total weight of the cosmetic.
7. The cosmetic according to claims 5 and 6, wherein the plant-derived telomerase composition is contained in an amount of 10% (mass fraction) based on the total weight of the cosmetic.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910301489.9A CN111821226A (en) | 2019-04-16 | 2019-04-16 | Plant-derived telomerase composition and novel application thereof in cosmetics |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910301489.9A CN111821226A (en) | 2019-04-16 | 2019-04-16 | Plant-derived telomerase composition and novel application thereof in cosmetics |
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| CN111821226A true CN111821226A (en) | 2020-10-27 |
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| CN201910301489.9A Pending CN111821226A (en) | 2019-04-16 | 2019-04-16 | Plant-derived telomerase composition and novel application thereof in cosmetics |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112618409A (en) * | 2021-01-12 | 2021-04-09 | 赵彬 | Cell activation regeneration nutrient based on telomerase technology |
| CN113230196A (en) * | 2021-05-13 | 2021-08-10 | 广州市涵美化妆品有限公司 | Anti-aging repair essence and preparation method thereof |
| CN113318029A (en) * | 2021-06-17 | 2021-08-31 | 广东柏俐臣生物科技有限公司 | Moisturizing lotion and preparation method thereof |
-
2019
- 2019-04-16 CN CN201910301489.9A patent/CN111821226A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112618409A (en) * | 2021-01-12 | 2021-04-09 | 赵彬 | Cell activation regeneration nutrient based on telomerase technology |
| CN113230196A (en) * | 2021-05-13 | 2021-08-10 | 广州市涵美化妆品有限公司 | Anti-aging repair essence and preparation method thereof |
| CN113318029A (en) * | 2021-06-17 | 2021-08-31 | 广东柏俐臣生物科技有限公司 | Moisturizing lotion and preparation method thereof |
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Addressee: Patent of Guangzhou shangning cosmetics technology Co.,Ltd. The person in charge Document name: Notice before the expiration of the time limit for actual examination request |
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Application publication date: 20201027 |
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