WO2019041293A1 - Système de commande intelligente permettant de concentrer un extrait de plante médicinale chinoise - Google Patents
Système de commande intelligente permettant de concentrer un extrait de plante médicinale chinoise Download PDFInfo
- Publication number
- WO2019041293A1 WO2019041293A1 PCT/CN2017/100120 CN2017100120W WO2019041293A1 WO 2019041293 A1 WO2019041293 A1 WO 2019041293A1 CN 2017100120 W CN2017100120 W CN 2017100120W WO 2019041293 A1 WO2019041293 A1 WO 2019041293A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- chinese herbal
- herbal medicine
- medicine extract
- heater
- control system
- Prior art date
Links
- 239000000284 extract Substances 0.000 title claims abstract description 49
- 241000411851 herbal medicine Species 0.000 title claims abstract description 44
- 238000000034 method Methods 0.000 claims abstract description 68
- 230000008569 process Effects 0.000 claims abstract description 59
- 230000009471 action Effects 0.000 claims abstract description 19
- 239000007788 liquid Substances 0.000 claims description 50
- 238000012544 monitoring process Methods 0.000 claims description 12
- 230000000694 effects Effects 0.000 claims description 9
- 238000001514 detection method Methods 0.000 claims description 8
- 230000003993 interaction Effects 0.000 claims description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 7
- 239000002699 waste material Substances 0.000 claims description 6
- 239000012141 concentrate Substances 0.000 claims description 3
- 238000001802 infusion Methods 0.000 claims description 3
- 239000000835 fiber Substances 0.000 claims description 2
- 238000012545 processing Methods 0.000 abstract description 13
- 238000005259 measurement Methods 0.000 abstract 3
- 238000004519 manufacturing process Methods 0.000 description 33
- 238000001704 evaporation Methods 0.000 description 30
- 230000008020 evaporation Effects 0.000 description 29
- 239000003814 drug Substances 0.000 description 22
- 238000010438 heat treatment Methods 0.000 description 14
- 238000005516 engineering process Methods 0.000 description 13
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 12
- 238000009835 boiling Methods 0.000 description 8
- 238000007726 management method Methods 0.000 description 8
- 239000010408 film Substances 0.000 description 7
- 239000000203 mixture Substances 0.000 description 7
- 238000010586 diagram Methods 0.000 description 6
- 239000012676 herbal extract Substances 0.000 description 6
- 238000012546 transfer Methods 0.000 description 6
- 239000000126 substance Substances 0.000 description 5
- 229940079593 drug Drugs 0.000 description 4
- 238000000605 extraction Methods 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 239000002904 solvent Substances 0.000 description 4
- 239000006260 foam Substances 0.000 description 3
- 230000036541 health Effects 0.000 description 3
- 238000007689 inspection Methods 0.000 description 3
- 239000003960 organic solvent Substances 0.000 description 3
- 239000002994 raw material Substances 0.000 description 3
- 230000001105 regulatory effect Effects 0.000 description 3
- 230000009286 beneficial effect Effects 0.000 description 2
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- 238000007418 data mining Methods 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 238000004821 distillation Methods 0.000 description 2
- 230000008030 elimination Effects 0.000 description 2
- 238000003379 elimination reaction Methods 0.000 description 2
- 238000005265 energy consumption Methods 0.000 description 2
- 230000005484 gravity Effects 0.000 description 2
- 230000002706 hydrostatic effect Effects 0.000 description 2
- 230000010354 integration Effects 0.000 description 2
- 238000012423 maintenance Methods 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 238000004088 simulation Methods 0.000 description 2
- 239000010409 thin film Substances 0.000 description 2
- 206010057040 Temperature intolerance Diseases 0.000 description 1
- 239000006286 aqueous extract Substances 0.000 description 1
- 230000001174 ascending effect Effects 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 238000005352 clarification Methods 0.000 description 1
- 238000009833 condensation Methods 0.000 description 1
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- 230000002349 favourable effect Effects 0.000 description 1
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- 238000009472 formulation Methods 0.000 description 1
- 230000008543 heat sensitivity Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000002386 leaching Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 238000013021 overheating Methods 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
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- 238000009834 vaporization Methods 0.000 description 1
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Images
Classifications
-
- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
- G05B19/00—Programme-control systems
- G05B19/02—Programme-control systems electric
- G05B19/418—Total factory control, i.e. centrally controlling a plurality of machines, e.g. direct or distributed numerical control [DNC], flexible manufacturing systems [FMS], integrated manufacturing systems [IMS] or computer integrated manufacturing [CIM]
- G05B19/41865—Total factory control, i.e. centrally controlling a plurality of machines, e.g. direct or distributed numerical control [DNC], flexible manufacturing systems [FMS], integrated manufacturing systems [IMS] or computer integrated manufacturing [CIM] characterised by job scheduling, process planning, material flow
-
- G—PHYSICS
- G05—CONTROLLING; REGULATING
- G05B—CONTROL OR REGULATING SYSTEMS IN GENERAL; FUNCTIONAL ELEMENTS OF SUCH SYSTEMS; MONITORING OR TESTING ARRANGEMENTS FOR SUCH SYSTEMS OR ELEMENTS
- G05B19/00—Programme-control systems
- G05B19/02—Programme-control systems electric
- G05B19/418—Total factory control, i.e. centrally controlling a plurality of machines, e.g. direct or distributed numerical control [DNC], flexible manufacturing systems [FMS], integrated manufacturing systems [IMS] or computer integrated manufacturing [CIM]
- G05B19/41875—Total factory control, i.e. centrally controlling a plurality of machines, e.g. direct or distributed numerical control [DNC], flexible manufacturing systems [FMS], integrated manufacturing systems [IMS] or computer integrated manufacturing [CIM] characterised by quality surveillance of production
Definitions
- Tube evaporator The heating chamber of the evaporator is composed of a tube member which is evaporated and concentrated by a tube wall heated by steam. There are coil type, external heating type, central circulation tube type and pump forced circulation type.
- Multi-effect concentrator the secondary steam generated by the pre-effect is introduced as heating steam into the evaporation device composed of another series-connected after-effect evaporator. Due to the repeated use of the secondary steam, a multi-effect evaporator can be formed, saving Energy to improve evaporation efficiency.
- Centrifugal thin film evaporator the liquid medicine is distributed into a film of 0.05 to 1 mm by centrifugation, and then re-passed.
- the heated surface of the conical disk is concentrated by evaporation. Because of high heat transfer coefficient and short heating time, it is suitable for evaporation and concentration of high heat sensitive materials.
- the device has high evaporation efficiency, but the structure is complicated and the price is relatively expensive.
- the existing traditional Chinese medicine extract is concentrated, the corresponding method and equipment are adopted according to the requirements of its nature and concentration degree, and the production process is controlled manually.
- the production personnel let the concentrated system run through the on-site instrument and manual valves, pumps and motors.
- the core parameters cannot be accurately and timely controlled. For example, the temperature must be controlled within ⁇ 1 degree of the original evaporation temperature; the pressure must be controlled within ⁇ 10 mbar of the set pressure; the accuracy of the product specific gravity three Double digits after reaching the decimal point.
- the main object of the present invention is to provide a centralized intelligent control system for extracting Chinese herbal medicines, which can realize automatic control of the concentrated processing production process of Chinese herbal medicine extracts, ensure the stability of process parameters in the concentrated production process, and improve the concentration treatment of Chinese herbal medicine extracts. Quality, reducing human resource costs.
- the primary station server is configured to receive real-time process parameters obtained by the process parameter detection module, compare the real-time process parameters with reference process parameters, and issue an action instruction to the device PLC control module;
- the Chinese herbal medicine extract concentration intelligent control system further comprises: a device initialization module, configured to control the all devices to be in an initial setting state when the system is started or when the system is closed.
- the Chinese herbal medicine extract liquid concentration intelligent control system of the invention can control and monitor the concentrated MVR subsystem equipment remotely in the central control room through the setting of the main station server, the equipment PLC control module and the process parameter detection module.
- the main parameters of the production formula and production cycle of the Chinese herbal extract can be solidified by the intelligent system, and no more personnel intervention will occur. In each link, no defective products will be caused by personnel mistakes, and the product quality can be improved to 99. %the above.
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- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Manufacturing & Machinery (AREA)
- Quality & Reliability (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Automation & Control Theory (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
La présente invention se rapporte à un système de commande intelligente permettant de concentrer un extrait de plante médicinale chinoise. L'invention commande automatiquement un processus de concentration d'un extrait de plante médicinale chinoise, et elle garantit la stabilité de paramètres de traitement pendant la concentration. Le système comprend un serveur de station maîtresse, un module de commande PLC de dispositif, un module de mesure de paramètres de traitement, et un terminal de commande d'opération. Le serveur de station maîtresse sert à recevoir des paramètres de traitement en temps réel obtenus par le module de mesure de paramètres de traitement, et à comparer les paramètres de traitement en temps réel à des paramètres de traitement de référence. Ce serveur de station maîtresse reçoit un paramètre de champ au moyen du module de commande PLC de dispositif, et il envoie une instruction d'action pour donner l'ordre au dispositif d'agir conformément aux exigences de traitement. Ledit module de mesure de paramètres de traitement permet d'obtenir les paramètres de traitement en temps réel, par l'intermédiaire d'un détecteur situé sur le dispositif, pendant la concentration. Le terminal de commande d'opération sert à configurer, selon les propriétés de l'extrait de plante médicinale chinoise, les paramètres de traitement de référence et une instruction de commande PLC de dispositif correspondante.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201780005105.8A CN108513633A (zh) | 2017-09-01 | 2017-09-01 | 一种中草药提取液浓缩智能化控制系统 |
PCT/CN2017/100120 WO2019041293A1 (fr) | 2017-09-01 | 2017-09-01 | Système de commande intelligente permettant de concentrer un extrait de plante médicinale chinoise |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/CN2017/100120 WO2019041293A1 (fr) | 2017-09-01 | 2017-09-01 | Système de commande intelligente permettant de concentrer un extrait de plante médicinale chinoise |
Publications (1)
Publication Number | Publication Date |
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WO2019041293A1 true WO2019041293A1 (fr) | 2019-03-07 |
Family
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Family Applications (1)
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PCT/CN2017/100120 WO2019041293A1 (fr) | 2017-09-01 | 2017-09-01 | Système de commande intelligente permettant de concentrer un extrait de plante médicinale chinoise |
Country Status (2)
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CN (1) | CN108513633A (fr) |
WO (1) | WO2019041293A1 (fr) |
Cited By (1)
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CN112023436A (zh) * | 2020-07-21 | 2020-12-04 | 广东工业大学 | 一种应用于中药提取浓缩工艺的增强现实系统 |
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CN110357818A (zh) * | 2019-06-25 | 2019-10-22 | 湖南正清制药集团股份有限公司 | 一种用于在青风藤中提取青藤碱的浓缩检测方法及装置 |
CN111897301B (zh) * | 2020-07-31 | 2022-04-15 | 杭州大远智控技术有限公司 | 一种中药提取自动化控制系统 |
CN114602209B (zh) * | 2022-03-07 | 2023-12-01 | 广东工业大学 | 一种车载式智能移动中药提取浓缩成套装备 |
CN114989239B (zh) * | 2022-07-05 | 2023-04-18 | 广西昌洲天然药业有限公司 | 一种从积雪草中分离羟基积雪草苷方法及计算机存储介质 |
CN114984071A (zh) * | 2022-07-05 | 2022-09-02 | 广西昌洲天然药业有限公司 | 从积雪草中提取积雪草总苷方法、装置、设备及介质 |
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- 2017-09-01 WO PCT/CN2017/100120 patent/WO2019041293A1/fr active Application Filing
- 2017-09-01 CN CN201780005105.8A patent/CN108513633A/zh active Pending
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