WO2018145277A1 - Hair care essence liquid and preparation method therefor - Google Patents

Hair care essence liquid and preparation method therefor Download PDF

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Publication number
WO2018145277A1
WO2018145277A1 PCT/CN2017/073130 CN2017073130W WO2018145277A1 WO 2018145277 A1 WO2018145277 A1 WO 2018145277A1 CN 2017073130 W CN2017073130 W CN 2017073130W WO 2018145277 A1 WO2018145277 A1 WO 2018145277A1
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parts
hair
hair care
preparation
care essence
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PCT/CN2017/073130
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French (fr)
Chinese (zh)
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潘瑞
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格兰比圣(深圳)科技有限公司
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Priority to PCT/CN2017/073130 priority Critical patent/WO2018145277A1/en
Publication of WO2018145277A1 publication Critical patent/WO2018145277A1/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/12Preparations containing hair conditioners

Definitions

  • the invention relates to the technical field of daily cosmetics, in particular to a hair care essence and a preparation method thereof.
  • Hair is an important part of the human body. It grows in the hair follicles, including the hair roots inside the hair follicles and the hair shafts that are exposed outside the skin. Hair can affect people's overall image. People with dark and dense hair tend to look more healthy and energetic. However, many people in real life have many types of damage, such as mechanical damage, chemical damage or heat treatment damage. It is characterized by dry and split hair, rare hair loss, increased white hair, etc., which brings certain troubles to normal life.
  • shampoo and hair care products on the market, including products that activate hair follicles and hair black hair. Although they improve hair whitening or hair thinning to a certain extent, these shampoo and hair care products often have effects. Poor, when used for a period of time, it is difficult to produce further hair care effects, can not effectively make the hair dense and black, and can not improve the hair dry hair problems. Therefore, it is necessary to find a more effective hair care product that promotes the blackening and densification of the hair, thereby better protecting the health of the hair.
  • the technical problem to be solved by the present invention is that it is difficult to further develop the hair care products in the prior art.
  • the hair care effect of hair care can not effectively make the hair thick and black, and can not improve the problem of dry hair and hair dry hair. It provides a hair care and hair care essence which can effectively make hair black and dense and effectively dry hair. Preparation.
  • a hair care essence liquid the raw materials of which include 50-120 parts of thyme, 10-30 parts of Polygonum multiflorum, 5-30 parts of soybean seeds, Rehmannia glutinosa 10 ⁇ 40 parts, 5 to 15 parts of licorice extract, 5 to 40 parts of saponin, 2 to 15 parts of ginkgo leaves, 5 to 30 parts of borneol, 5 to 20 parts of lemon juice and 3 to 10 parts of tea seed oil.
  • thyme has the effect of nourishing blood and nourishing the hair, and is an ideal strong agent for nourishing liver and kidney and raising five internal organs.
  • Polygonum multiflorum containing nutrients such as lecithin, has the function of nourishing blood and hurricane, can regulate nerve and endocrine function, nourish hair roots, promote the formation of hair melanin and make hair darker.
  • Polygonum multiflorum also contains chrysophanol and a large amount of starch. After hydrolysis of starch, it can produce glucose. It has a good moisturizing effect and is the best traditional Chinese medicine for formulating hair conditioner.
  • Soybean seed rich in soy lecithin, is a natural high-nutrient fortifier and surfactant. It has excellent transdermal absorption effect, which can quickly penetrate the active ingredients in hair care products into the deep layer of hair, and greatly increase the transdermal absorption rate of tissue cells, so that various active ingredients can play a greater role.
  • Rehmannia glutinosa sweet, into the liver, kidney, with blood and nourishing yin, Yijing fill the marrow.
  • Licorice extract refers to the active ingredient extract extracted from licorice by using the existing processing technology; it has the reducing property of inhibiting melanin, makes the skin white and smooth, and has strong absorption effect on ultraviolet light and visible light.
  • Saponin a drug containing saponin, can clear away heat and dampness, remove excess fat, and smoothly block hair follicles. It has good effect on preventing hair loss and black hair, does not stimulate the scalp; contains saponin, has high foaming properties and A certain decontamination ability, after shampooing with soapy water, the hair is fluffy and soft, bright, with anti-dandruff and anti-itch effect.
  • Ginkgo biloba leaves contain a variety of ingredients, mainly flavonoids, azlactones, organic acids, organic alcohols, minerals, vitamins, etc. Flavonoids are powerful oxygen free radical scavengers that protect the skin. Cells are not affected by the excessive oxidation of oxygen free radicals.
  • the addition of Ginkgo biloba extract to the hair care product can completely remove the dirt in the pores.
  • the lactones in the Ginkgo biloba extract have a broad-spectrum bactericidal effect.
  • Lemon juice is the juice obtained by squeezed fresh lemon.
  • Lemon juice contains sugar, vitamin C, vitamin B1, B2, niacin, calcium, phosphorus, iron and other nutrients.
  • Main effects bactericidal effect; eliminate fatigue, enhance immunity, delay aging, maintain skin elasticity, etc., can reduce dandruff and prevent hair loss.
  • Tea seed oil is extracted from the fruit of Camellia oleifera. It has moisturizing, moisturizing, and hair-raising functions. It is used for hair care, preventing hair breakage and hair loss, rubbing after bathing, enhancing skin elasticity, and treating the elderly. Itchy skin in winter.
  • the hair care essence provided by the invention can effectively promote the hair to become black and dense while dandruff and itching, thereby better protecting the health of the hair.
  • the invention also provides a preparation method of the above hair care essence liquid, wherein the thyme, polygonum multiflorum, soybean seed, rehmannia root, licorice extract, soapy, ginkgo leaf, borneol and lemon juice are mixed according to respective weight parts. , obtaining the mixed raw materials;
  • the mixed raw material is added to an aqueous ethanol solution, heated to 60-80 ° C, stirred uniformly, kept for 2 to 4 hours, and then cooled to room temperature;
  • the cooled raw material is filtered to obtain a filtrate
  • the prepared hair care essence can effectively promote the blackening and densification of the hair, thereby better protecting the hair health.
  • the hair care essence of the present invention comprises, by weight, 50 to 120 parts of thyme, 10 to 30 parts of Polygonum multiflorum, 5 to 30 parts of soybean seeds, 10 to 40 parts of rehmannia glutinosa, and 5 to 15 parts of licorice extract. 5 to 40 parts of soap, 2 to 15 parts of ginkgo leaves, 5 to 30 parts of borneol, 5 to 20 parts of lemon juice and 3 to 10 parts of tea seed oil.
  • the hair care essence of the invention comprises, by weight, 50 parts of thyme, 10 parts of Polygonum, 5 parts of soybean seeds, 10 parts of Rehmannia glutinosa, 5 parts of licorice extract, 5 parts of saponin, 2 parts of Ginkgo biloba, 5 parts of borneol, 5 parts of lemon juice and 3 parts of tea seed oil.
  • the hair care essence of the invention comprises, by weight, 120 parts of thyme, 30 parts of Polygonum, 30 parts of soybean seeds, 40 parts of Rehmannia glutinosa, 15 parts of licorice extract, 40 parts of saponin, 15 parts of ginkgo leaves, 30 parts of borneol, 20 parts of lemon juice and 10 parts of tea seed oil.
  • the hair care essence of the invention comprises, by weight, thyme 80, 15 parts of Polygonum, 15 parts of soybean seeds, 20 parts of Rehmannia glutinosa, 7 parts of licorice extract, 15 parts of saponin, 5 parts of ginkgo biloba, borneol 15 Serve 10 parts of lemon juice and 5 parts of tea seed oil.
  • the hair care essence of the present invention comprises, by weight, 100 parts of thyme, 25 parts of Polygonum, 20 parts of soybean seeds, 30 parts of Rehmannia glutinosa, 10 parts of licorice extract, 30 parts of saponin, and 10 parts of ginkgo leaves. 20 parts of borneol, 15 parts of lemon juice and 8 parts of tea seed oil.
  • the hair care essence of the invention comprises, by weight, 90 parts of thyme, 20 parts of Polygonum, 18 parts of soybean seeds, 25 parts of Rehmannia glutinosa, 8 parts of licorice extract, 24 parts of saponin, 8 parts of ginkgo leaves, 18 parts of borneol, 13 parts of lemon juice and 6 parts of tea seed oil.
  • the hair care essence provided by the invention can effectively promote the blackening and densification of the hair, effectively solve the problem of dry hair and hairiness of the hair, thereby better protecting the hair health.
  • the preparation method of the hair care essence provided by the invention comprises the following steps:
  • This embodiment provides a method for preparing a hair care essence, comprising the following steps:
  • S1 50 parts of thyme, 10 parts of Polygonum, 5 parts of soybean seeds, 10 parts of rehmannia, 5 parts of licorice extract, 5 parts of soap, 2 parts of ginkgo leaves, 5 parts of borneol, 5 parts of lemon juice, by weight Mix with 3 parts of tea seed oil;
  • This embodiment provides a method for preparing a hair care essence, comprising the following steps:
  • S1 in parts by weight, 120 parts of thyme, 30 parts of Polygonum, 30 parts of soybean seeds, 40 parts of Rehmannia glutinosa, 15 parts of honeysuckle, 40 parts of soap, 15 parts of ginkgo leaves, 30 parts of borneol, 20 parts of lemon juice mixing;
  • This embodiment provides a method for preparing a hair care essence, comprising the following steps:
  • S1 80 parts of thyme, 15 parts of Polygonum, 15 parts of soybean seeds, 20 parts of Rehmannia glutinosa, 7 parts of honeysuckle, 15 parts of saponin, 5 parts of ginkgo leaves, 15 parts of borneol and 10 parts of lemon juice are used in parts by weight. mixing;
  • This embodiment provides a method for preparing a hair care essence, comprising the following steps:
  • S1 100 parts by weight of thyme, 25 parts of Polygonum, 20 parts of soybean seeds, 30 parts of rehmannia root, 10 parts of honeysuckle, 30 parts of soap, 10 parts of ginkgo leaves, 20 parts of borneol and 15 parts of lemon juice. mixing;
  • This embodiment provides a method for preparing a hair care essence, comprising the following steps:
  • S1 In parts by weight, 90 parts of thyme, 20 parts of Polygonum, 18 parts of soybean seeds, 25 parts of Rehmannia glutinosa, 8 parts of honeysuckle, 24 parts of saponin, 8 parts of ginkgo leaves, 18 parts of borneol and 13 parts of lemon juice mixing;
  • the traditional Chinese medicine material for nourishing blood and nourishing the hair is used as a raw material, and the active ingredient is extracted to prepare the hair care essence liquid, which can effectively promote the hair to become black and dense. Thereby better protection of hair health.
  • the hair care essence solution of the invention is harmless to the scalp, and is used for hair growth and hair growth, and the curative effect is obvious.
  • the hair care essence prepared by the sixth embodiment to the tenth embodiment of the present invention was studied for pharmacodynamics, and a hair-raising essence of the hair was used as a control group on the market.
  • the specific methods and results are as follows:
  • mice Seventy mice were depilated with barium sulfide, the hair removal area was 3 cm ⁇ 3 cm, and then randomly divided into seven groups of A, B, C, D, E, F, and G, with 10 in each group.
  • the obtained hair care essence solution, the group D was applied with the hair care essence prepared in the ninth embodiment, the group E was applied with the hair care essence prepared in the tenth embodiment, and the group F was applied with a hair-raising essence of the hair on the market as a control group.
  • Group G smear was used as a control group, and each mouse was applied once every two days.
  • Subject selection criteria and grouping 280 subjects with more white hair were selected and divided into 14 groups: 30-40 for men and women, 10 for A1, 30-40 for men and women 10 people are B1, 10-40 for men and women are C1, 30-40 for men and women are D1, 30-40 for men and women are E1, 30-40 for men and women 10
  • F1 group 10 males and 30s in 30-40 years old are in the G1 group
  • 10 men and women in 40-50 years old are in the A2 group
  • 10 men and women in the 40-50 age group are in the B2 group
  • 10 in the 40-50 year old men and women are in the C2 group.
  • 40 men and women of 40-50 years old are D2 group
  • 10 men and women of 40-50 years old are E2 group
  • 10 men and women of 40-500 years old are F2 group
  • 10 men and women of 40-50 years old are G2 group.
  • Test product and method of use All subjects used the test product once every 3 days, and each time the same amount, 2 ml corresponding products: Group A applied the hair care essence prepared in Example 6, Group B applied Example 7 The hair care essence prepared by the preparation, the group C was applied to the hair care essence prepared in the eighth embodiment, the group D was applied to the hair care essence prepared in the ninth embodiment, and the group E was applied to the hair care essence prepared in the tenth embodiment.
  • Group F smeared a hair-raising essence on the market as a control group, and group G applied water as a control group for 6 months.
  • RESULTS The heads of the subjects were divided into five regions: front, middle, left, right and back. They were respectively positioned. Each standard point of 1 cm2 was selected as the measurement position, and the average number of white hairs was taken. After using the product, the average number of white hairs in the area is averaged as described above, and the number of white hair roots after using the product is averaged. The value is divided by the average number of white hair roots before using the product, and the ratio of white hair to black is calculated. The average ratio of white hair blackening of all subjects in this group is recorded in the following table, as shown in Table 2:
  • the gray-to-black ratio of the subjects in each group is white for a subject of 30-40 years after continuous use for 6 months.
  • the ratio of blackening is 63%-76%, and the ratio of black hair to black is only 33% when using a hair styling essence on the market; for subjects 40-50 years old, the ratio of black hair to black is 57. %-65%, and using a hair-raising essence on the market, the ratio of white hair to black is only 27%.
  • the hair care essence prepared by the E group (Example 10) is more effective.
  • the above results show that the hair care essence prepared by the invention can nourish the hair follicle, promote the blackening of the hair, and effectively play the role of raising hair.
  • Subject selection criteria and grouping 280 subjects with sparse hair and partial shedding were selected and divided into 14 groups: 10-40 for men and women, A1 for men and women, 30-40 for men and women.
  • 10 people are in the B1 group
  • 10-40 males and 30s are in the C1 group
  • 30-40 years old men and 10 each are in the D1 group
  • 30-40 years old men and women are 10 in the E1 group
  • 30-40 years old in the men and women are 10 in the group
  • group F1 10 males and 30s in 30-40 years old are G1 group
  • 10 men and women in 40-50 years old are A2 group
  • 10 men and women in 40-50 years old are B2 group
  • 10 men and women in 40-50 years old are C2 group.
  • 10 men and women are in D2 group
  • 40-50 years old men and 10 are E2 group
  • 40-500 year old men and 10 each are F2 group
  • 40-50 year old men and women are 10 persons in G2 group.
  • Test product and method of use All subjects used the test product once every 3 days, and each time the same amount, 2 ml corresponding products: Group A applied the hair care essence prepared in Example 6, Group B applied Example 7 The hair care essence prepared by the preparation, the group C was applied to the hair care essence prepared in the eighth embodiment, the group D was applied to the hair care essence prepared in the ninth embodiment, and the group E was applied to the hair care essence prepared in the tenth embodiment.
  • Group F smeared a hair-raising essence on the market as a control group, and group G applied water as a control group for 6 months.
  • RESULTS The heads of the subjects were divided into five regions: front, middle, left, right and back. They were respectively positioned. Each standard point of 1 cm2 was selected as the measurement position, and the average number of hair roots was taken. After using the product, the average number of hairs in the area is averaged as described above, and the average number of hair roots after using the product is subtracted from the average number of hair roots before use, and the number of hairs before being used is divided by the number of hairs before use. The average value, the growth ratio of the number of hairs was calculated, and the average growth rate of the hair number of all the subjects in the group was calculated in the following table, as shown in Table 3:
  • Table 3 shows the average growth rate of hair of each group before and after using the essence
  • the increase in the number of hairs is large, and the proportion of hair growth is increased for subjects aged 30-40 years after continuous use for 6 months. It is 149%-169%, and the growth rate of hair is only 93% when using a hair styling essence on the market; for a 40-50 year old, the growth rate of hair is 131%-147. %, and using a hair-raising essence on the market, the growth rate of hair is only 82%.
  • the hair care essence prepared in the tenth embodiment is more effective. The above results show that the hair care essence prepared by the invention can nourish the hair follicle, promote hair growth, and effectively play the role of hair growth and hair growth.
  • the above description is only a preferred embodiment of the present invention, and is not intended to limit the present invention.
  • the general position of the main board and the heat dissipation module may be appropriately adjusted according to the needs of the smart cleaning device itself, or may be The actual heat source status of the product is modified to adjust the position and performance of the heat dissipation module and the temperature equalizing material to achieve a balanced state.
  • the invention is capable of various modifications and changes. Any modifications, equivalent substitutions, improvements, etc. within the spirit and scope of the invention are intended to be included within the scope of the appended claims.

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Abstract

A hair care essence liquid and a preparation method therefor, the raw materials comprising, in parts by weight: 50-120 parts of thyme, 10-30 parts of Fallopia multiflora, 5-30 parts of soybean seed, 10-40 parts of prepared Radix rehmanniae, 5-15 parts of licorice extract, 5-40 parts of Gleditsia sinensis, 2-15 parts of Ginkgo biloba leaf, 5-30 parts of borneol, 5-20 parts of lemon juice and 3-10 parts of tea seed oil. The provided hair care essence liquid may effectively promote hair becoming darker and thicker, thereby better protecting hair health.

Description

一种护发精华液及其制备方法Hair care essence and preparation method thereof 技术领域Technical field
本发明涉及日用化妆品技术领域,具体涉及一种护发精华液及其制备方法。The invention relates to the technical field of daily cosmetics, in particular to a hair care essence and a preparation method thereof.
背景技术Background technique
头发是人体的重要组成部分,它生长在毛囊中,包括毛囊内部的毛根和露在皮面外的毛干。头发能影响人的整体形象,拥有乌黑稠密的头发的人往往看起来更为健康活力,然而,现实生活中很多人的头发却存在多种类型的损伤,如机械损伤、化学损伤或热处理损伤等,表现为头发干枯分叉、稀少脱发、白发增多等,给正常的生活带来一定的困扰。Hair is an important part of the human body. It grows in the hair follicles, including the hair roots inside the hair follicles and the hair shafts that are exposed outside the skin. Hair can affect people's overall image. People with dark and dense hair tend to look more healthy and energetic. However, many people in real life have many types of damage, such as mechanical damage, chemical damage or heat treatment damage. It is characterized by dry and split hair, rare hair loss, increased white hair, etc., which brings certain troubles to normal life.
现在市面上存在各种各样的洗发护发产品,包括活化毛囊生发乌发等产品,它们虽然在一定程度上改善了头发变白或头发稀疏的情况,但是这些洗发护发产品往往效果欠佳,当使用一段时间后,难以产生进一步的养发护发效果,无法有效的让头发稠密乌黑,且无法改善头发干枯毛躁的问题。因此,需要寻找更有效的促使头发变黑变密的护发产品,从而更好的保护发部健康。There are a variety of shampoo and hair care products on the market, including products that activate hair follicles and hair black hair. Although they improve hair whitening or hair thinning to a certain extent, these shampoo and hair care products often have effects. Poor, when used for a period of time, it is difficult to produce further hair care effects, can not effectively make the hair dense and black, and can not improve the hair dry hair problems. Therefore, it is necessary to find a more effective hair care product that promotes the blackening and densification of the hair, thereby better protecting the health of the hair.
发明内容Summary of the invention
本发明所要解决的技术问题是,针对现有技术中护发产品难以产生进一步 的养发护发效果,无法有效的让头发稠密乌黑,且无法改善头发干枯毛躁的问题,提供一种能够有效的促使头发变黑变密且有效改善头发干枯的护发护发精华液及其制备方法。The technical problem to be solved by the present invention is that it is difficult to further develop the hair care products in the prior art. The hair care effect of hair care can not effectively make the hair thick and black, and can not improve the problem of dry hair and hair dry hair. It provides a hair care and hair care essence which can effectively make hair black and dense and effectively dry hair. Preparation.
本发明解决其技术问题所采用的技术方案是:一种护发精华液,其原料按重量份计包括:百里香50~120份,何首乌10~30份,大豆籽5~30份,熟地黄10~40份,甘草提取物5~15份,皂英5~40份,银杏叶2~15份,冰片5~30份,柠檬汁5~20份和茶籽油3~10份。The technical solution adopted by the invention to solve the technical problem is: a hair care essence liquid, the raw materials of which include 50-120 parts of thyme, 10-30 parts of Polygonum multiflorum, 5-30 parts of soybean seeds, Rehmannia glutinosa 10 ~40 parts, 5 to 15 parts of licorice extract, 5 to 40 parts of saponin, 2 to 15 parts of ginkgo leaves, 5 to 30 parts of borneol, 5 to 20 parts of lemon juice and 3 to 10 parts of tea seed oil.
其中,百里香,具有补血生津、养发之功效,为滋肝肾、养五脏的理想强壮剂。Among them, thyme has the effect of nourishing blood and nourishing the hair, and is an ideal strong agent for nourishing liver and kidney and raising five internal organs.
何首乌,含有卵磷脂等营养成分,具有养血祛风之功,可调节神经与内分泌功能,营养发根,促使头发黑色素的生成,使头发更黑。同时,何首乌还含有大黄酚和大量淀粉,淀粉水解后,能生成葡萄糖,具有很好的润发作用,是配制头发调理剂的最佳中药原料。Polygonum multiflorum, containing nutrients such as lecithin, has the function of nourishing blood and hurricane, can regulate nerve and endocrine function, nourish hair roots, promote the formation of hair melanin and make hair darker. At the same time, Polygonum multiflorum also contains chrysophanol and a large amount of starch. After hydrolysis of starch, it can produce glucose. It has a good moisturizing effect and is the best traditional Chinese medicine for formulating hair conditioner.
大豆籽,含有丰富的大豆卵磷脂,是一种天然高营养强化剂和表面活性剂。它具有优良的透皮吸收功效,可使护发品中有效成分迅速渗透到头发深层,同时大大提高组织细胞的透皮吸收率,使各种有效成分更大地发挥作用。Soybean seed, rich in soy lecithin, is a natural high-nutrient fortifier and surfactant. It has excellent transdermal absorption effect, which can quickly penetrate the active ingredients in hair care products into the deep layer of hair, and greatly increase the transdermal absorption rate of tissue cells, so that various active ingredients can play a greater role.
熟地黄,味甘,入肝、肾经,具有补血滋阴、益精填髓功效。Rehmannia glutinosa, sweet, into the liver, kidney, with blood and nourishing yin, Yijing fill the marrow.
甘草提取物是指利用现有加工技术从甘草中提取的有效成分提取液;具有抑制黑色素的还原性能,使皮肤洁白光滑,对紫外光和可见光具有较强的吸收作用。Licorice extract refers to the active ingredient extract extracted from licorice by using the existing processing technology; it has the reducing property of inhibiting melanin, makes the skin white and smooth, and has strong absorption effect on ultraviolet light and visible light.
皂英,含皂角类成分的药物,能够清热化湿、祛除多余脂肪、通畅阻塞毛囊,对防脱发和乌发效果颇佳,不会刺激头皮;含有皂甙,具有较高的发泡性和一定的去污能力,用皂英水洗发后,头发蓬松柔软、光亮,有去屑止痒作用。 Saponin, a drug containing saponin, can clear away heat and dampness, remove excess fat, and smoothly block hair follicles. It has good effect on preventing hair loss and black hair, does not stimulate the scalp; contains saponin, has high foaming properties and A certain decontamination ability, after shampooing with soapy water, the hair is fluffy and soft, bright, with anti-dandruff and anti-itch effect.
银杏叶,提取物中含有多种成分,主要有黄酮类、萜内酯类、有机酸类、有机醇类、矿物质、维生素等,其中黄酮是强有力的氧自由基清除剂,能保护皮肤细胞不受氧自由基过度氧化的影响。在护发品中加入银杏叶提取物可以彻底清除毛孔深处污物,此外,银杏提取物中的内酯类物具有广谱杀菌作用。Ginkgo biloba leaves contain a variety of ingredients, mainly flavonoids, azlactones, organic acids, organic alcohols, minerals, vitamins, etc. Flavonoids are powerful oxygen free radical scavengers that protect the skin. Cells are not affected by the excessive oxidation of oxygen free radicals. The addition of Ginkgo biloba extract to the hair care product can completely remove the dirt in the pores. In addition, the lactones in the Ginkgo biloba extract have a broad-spectrum bactericidal effect.
冰片,乌发养发,促进吸收,本身能透皮吸收,并能促进其他药物的透皮过程,是一种有效的透皮促进剂。冰片在不同的溶剂中具有不同的透皮速率,细胞间脂质通透是冰片经皮渗透的重要途径。Borneol, black hair to raise hair, promote absorption, itself can be absorbed through the skin, and can promote the transdermal process of other drugs, is an effective transdermal enhancer. Borneol has different transdermal rates in different solvents, and lipid permeation between cells is an important way for percutaneous penetration of borneol.
柠檬汁,是新鲜柠檬经榨挤后得到的汁液。柠檬汁含有糖类、维生素c、维生素B1、B2,烟酸、钙、磷、铁等营养成分。主要功效:杀菌作用;消除疲劳、增强免疫力、延缓衰老、保持肌肤弹性等等,可减少头皮屑,防止头发脱落。Lemon juice is the juice obtained by squeezed fresh lemon. Lemon juice contains sugar, vitamin C, vitamin B1, B2, niacin, calcium, phosphorus, iron and other nutrients. Main effects: bactericidal effect; eliminate fatigue, enhance immunity, delay aging, maintain skin elasticity, etc., can reduce dandruff and prevent hair loss.
茶籽油,是从油茶树的果实中萃取出的,具有保湿、滋润、乌发养颜功能,用于护发,可防头发断裂和脱发,浴后擦身,增强皮肤弹性,并治老年人冬季皮肤瘙痒。Tea seed oil is extracted from the fruit of Camellia oleifera. It has moisturizing, moisturizing, and hair-raising functions. It is used for hair care, preventing hair breakage and hair loss, rubbing after bathing, enhancing skin elasticity, and treating the elderly. Itchy skin in winter.
本发明提供的护发精华液,可以有效的促使头发变黑变密同时去屑止痒,从而更好的保护发部健康。The hair care essence provided by the invention can effectively promote the hair to become black and dense while dandruff and itching, thereby better protecting the health of the hair.
本发明还提供了一种上述护发精华液的制备方法,将所述百里香、何首乌、大豆籽、熟地黄、甘草提取物、皂英、银杏叶、冰片和柠檬汁按相应的重量份进行混合,得到混合后的原料;The invention also provides a preparation method of the above hair care essence liquid, wherein the thyme, polygonum multiflorum, soybean seed, rehmannia root, licorice extract, soapy, ginkgo leaf, borneol and lemon juice are mixed according to respective weight parts. , obtaining the mixed raw materials;
将所述混合后的原料加入乙醇水溶液中,加热至60~80℃,搅拌均匀,保温2~4小时,再降温至常温;The mixed raw material is added to an aqueous ethanol solution, heated to 60-80 ° C, stirred uniformly, kept for 2 to 4 hours, and then cooled to room temperature;
将所述降温后的原料进行过滤,得到滤液;The cooled raw material is filtered to obtain a filtrate;
在所述滤液中加入相应重量份的所述茶籽油、蜂胶、防腐剂和乳化稳定剂, 混合均匀,浓缩体积,真空保存得精华液成品。Adding the corresponding parts by weight of the tea seed oil, propolis, preservative and emulsion stabilizer to the filtrate, Mix well, concentrate the volume, and store the essence in vacuum.
采用本发明提供的护发精华液的制备方法,制备得到的护发精华液可以有效的促使头发变黑变密,从而更好的保护发部健康。By adopting the preparation method of the hair care essence provided by the invention, the prepared hair care essence can effectively promote the blackening and densification of the hair, thereby better protecting the hair health.
具体实施方式detailed description
为了使本发明的目的、技术方案及优点更加清楚明白,以下结合附图及实施例,对本发明进行进一步详细说明。应当理解,此处所描述的具体实施例仅用以解释本发明,并不用于限定本发明。The present invention will be further described in detail below with reference to the accompanying drawings and embodiments. It is understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
本发明的护发精华液,其原料按重量份计包括:百里香50~120份,何首乌10~30份,大豆籽5~30份,熟地黄10~40份,甘草提取物5~15份,皂英5~40份,银杏叶2~15份,冰片5~30份,柠檬汁5~20份和茶籽油3~10份。The hair care essence of the present invention comprises, by weight, 50 to 120 parts of thyme, 10 to 30 parts of Polygonum multiflorum, 5 to 30 parts of soybean seeds, 10 to 40 parts of rehmannia glutinosa, and 5 to 15 parts of licorice extract. 5 to 40 parts of soap, 2 to 15 parts of ginkgo leaves, 5 to 30 parts of borneol, 5 to 20 parts of lemon juice and 3 to 10 parts of tea seed oil.
下面结合具体实施例对本发明作进一步说明。The invention will now be further described in conjunction with specific embodiments.
实施例一Embodiment 1
本发明的护发精华液,其原料按重量份计包括:百里香50份,何首乌10份,大豆籽5份,熟地黄10份,甘草提取物5份,皂英5份,银杏叶2份,冰片5份,柠檬汁5份和茶籽油3份。The hair care essence of the invention comprises, by weight, 50 parts of thyme, 10 parts of Polygonum, 5 parts of soybean seeds, 10 parts of Rehmannia glutinosa, 5 parts of licorice extract, 5 parts of saponin, 2 parts of Ginkgo biloba, 5 parts of borneol, 5 parts of lemon juice and 3 parts of tea seed oil.
实施例二Embodiment 2
本发明的护发精华液,其原料按重量份计包括:百里香120份,何首乌30份,大豆籽30份,熟地黄40份,甘草提取物15份,皂英40份,银杏叶15份,冰片30份,柠檬汁20份和茶籽油10份。The hair care essence of the invention comprises, by weight, 120 parts of thyme, 30 parts of Polygonum, 30 parts of soybean seeds, 40 parts of Rehmannia glutinosa, 15 parts of licorice extract, 40 parts of saponin, 15 parts of ginkgo leaves, 30 parts of borneol, 20 parts of lemon juice and 10 parts of tea seed oil.
实施例三Embodiment 3
本发明的护发精华液,其原料按重量份计包括:百里香80,何首乌15份,大豆籽15份,熟地黄20份,甘草提取物7份,皂英15份,银杏叶5份,冰片15 份,柠檬汁10份和茶籽油5份。The hair care essence of the invention comprises, by weight, thyme 80, 15 parts of Polygonum, 15 parts of soybean seeds, 20 parts of Rehmannia glutinosa, 7 parts of licorice extract, 15 parts of saponin, 5 parts of ginkgo biloba, borneol 15 Serve 10 parts of lemon juice and 5 parts of tea seed oil.
实施例四Embodiment 4
本发明的护发精华液,其原料按重量份计包括:百里香100份,何首乌25份,大豆籽20份,熟地黄30份,甘草提取物10份,皂英30份,银杏叶10份,冰片20份,柠檬汁15份和茶籽油8份。The hair care essence of the present invention comprises, by weight, 100 parts of thyme, 25 parts of Polygonum, 20 parts of soybean seeds, 30 parts of Rehmannia glutinosa, 10 parts of licorice extract, 30 parts of saponin, and 10 parts of ginkgo leaves. 20 parts of borneol, 15 parts of lemon juice and 8 parts of tea seed oil.
实施例五Embodiment 5
本发明的护发精华液,其原料按重量份计包括:百里香90份,何首乌20份,大豆籽18份,熟地黄25份,甘草提取物8份,皂英24份,银杏叶8份,冰片18份,柠檬汁13份和茶籽油6份。The hair care essence of the invention comprises, by weight, 90 parts of thyme, 20 parts of Polygonum, 18 parts of soybean seeds, 25 parts of Rehmannia glutinosa, 8 parts of licorice extract, 24 parts of saponin, 8 parts of ginkgo leaves, 18 parts of borneol, 13 parts of lemon juice and 6 parts of tea seed oil.
当然,除了实施例一至实施例五列举的情况,采用其他重量份的百里香、何首乌、大豆籽、熟地黄、甘草提取物、皂英、银杏叶、冰片和柠檬汁为原料来制备护发精华液也是可以的。Of course, in addition to the examples listed in the first embodiment to the fifth embodiment, other weight parts of thyme, polygonum multiflorum, soybean seed, rehmannia root, licorice extract, soap, ginkgo leaf, borneol and lemon juice are used as raw materials to prepare hair care essence. it is also fine.
本发明提供的护发精华液,可以有效的促使头发变黑变密,有效解决头发干枯毛躁的问题,从而更好的保护发部健康。The hair care essence provided by the invention can effectively promote the blackening and densification of the hair, effectively solve the problem of dry hair and hairiness of the hair, thereby better protecting the hair health.
另外,针对本发明的护发精华液,本发明提供的护发精华液的制备方法,包括以下步骤:In addition, for the hair care essence of the present invention, the preparation method of the hair care essence provided by the invention comprises the following steps:
S1:将原料百里香、何首乌、大豆籽、熟地黄、甘草提取物、皂英、银杏叶、冰片和柠檬汁按相应的重量份进行混合,得到混合后的原料;S1: mixing raw thyme, polygonum multiflorum, soybean seed, rehmannia root, licorice extract, soap, ginkgo leaf, borneol and lemon juice according to the corresponding parts by weight to obtain a mixed raw material;
S2:将所述混合后的原料加入乙醇水溶液中,加热至60~80℃,搅拌均匀,保温2~4小时,再降温至常温;S2: adding the mixed raw material to an aqueous ethanol solution, heating to 60-80 ° C, stirring uniformly, keeping warm for 2 to 4 hours, and then cooling to normal temperature;
S3:将所述降温后的原料进行过滤,得到滤液;S3: filtering the cooled raw material to obtain a filtrate;
S4:在所述滤液中加入相应重量份的所述茶籽油、蜂胶、防腐剂和乳化稳定剂,混合均匀,浓缩体积,真空保存得精华液成品。 S4: adding the corresponding parts by weight of the tea seed oil, propolis, preservative and emulsion stabilizer to the filtrate, mixing uniformly, concentrating the volume, and preserving the finished liquid in a vacuum.
下面结合具体实施例对本发明提供的护发精华液的制备方法作进一步说明。The preparation method of the hair care essence provided by the present invention will be further described below in conjunction with specific embodiments.
实施例六Embodiment 6
本实施例提供了一种护发精华液的制备方法,包括如下步骤:This embodiment provides a method for preparing a hair care essence, comprising the following steps:
S1:以重量份计,将50份百里香,10份何首乌,5份大豆籽,10份熟地黄,5份甘草提取物,5份皂英,2份银杏叶,5份冰片,5份柠檬汁和3份茶籽油进行混合;S1: 50 parts of thyme, 10 parts of Polygonum, 5 parts of soybean seeds, 10 parts of rehmannia, 5 parts of licorice extract, 5 parts of soap, 2 parts of ginkgo leaves, 5 parts of borneol, 5 parts of lemon juice, by weight Mix with 3 parts of tea seed oil;
S2:在混合后的总重量为100份原料加入800份乙醇水溶液中,其中乙醇水溶液中乙醇和水的体积比为2∶1,将混合物加热至55℃,搅拌均匀,保温3小时,再降温至常温;S2: 100 parts of the total weight after mixing is added to 800 parts of aqueous ethanol solution, wherein the volume ratio of ethanol to water in the aqueous ethanol solution is 2:1, the mixture is heated to 55 ° C, stirred uniformly, kept for 3 hours, and then cooled. To normal temperature;
S3:将降温后的原料进行用80目筛进行过滤,得到滤液;S3: filtering the cooled raw material with an 80 mesh sieve to obtain a filtrate;
S4:在滤液中加入3份茶籽油、蜂胶、防腐剂山梨酸钾和乳化稳定剂羟乙基纤维素,山梨酸钾的质量为所得滤液质量的0.1%,羟乙基纤维素的质量为所得滤液质量的2%,混合均匀,浓缩体积至原体积的10%,真空保存得精华液成品。S4: 3 parts of tea seed oil, propolis, preservative potassium sorbate and emulsion stabilizer hydroxyethyl cellulose are added to the filtrate. The mass of potassium sorbate is 0.1% of the mass of the obtained filtrate, and the mass of hydroxyethyl cellulose is The obtained filtrate was 2% of the mass, uniformly mixed, and concentrated to a volume of 10% of the original volume, and stored in a vacuum to obtain a finished product.
实施例七Example 7
本实施例提供了一种护发精华液的制备方法,包括如下步骤:This embodiment provides a method for preparing a hair care essence, comprising the following steps:
S1:以重量份计,将120份百里香,30份何首乌,30份大豆籽,40份熟地黄,15份忍冬花,40份皂英,15份银杏叶,30份冰片,20份柠檬汁进行混合;S1: in parts by weight, 120 parts of thyme, 30 parts of Polygonum, 30 parts of soybean seeds, 40 parts of Rehmannia glutinosa, 15 parts of honeysuckle, 40 parts of soap, 15 parts of ginkgo leaves, 30 parts of borneol, 20 parts of lemon juice mixing;
S2:在混合后的总重量为340份原料加入5100份乙醇水溶液中,其中乙醇水溶液中乙醇和水的体积比为2∶1,将混合物加热至55℃,搅拌均匀,保温4小时,再降温至常温;S2: The total weight after mixing is 340 parts of raw materials added to 5100 parts of aqueous ethanol solution, wherein the volume ratio of ethanol to water in the aqueous ethanol solution is 2:1, the mixture is heated to 55 ° C, stirred uniformly, kept for 4 hours, and then cooled. To normal temperature;
S3:将降温后的原料进行用80目筛进行过滤,得到滤液; S3: filtering the cooled raw material with an 80 mesh sieve to obtain a filtrate;
S4:在滤液中加入10份茶籽油、蜂胶防腐剂山梨酸钾和乳化稳定剂羟乙基纤维素,山梨酸钾的质量为所得滤液质量的0.2%,羟乙基纤维素的质量为所得滤液质量的10%,混合均匀,浓缩体积至原体积的10%,真空保存得精华液成品。S4: 10 parts of tea seed oil, propolis preservative potassium sorbate and emulsion stabilizer hydroxyethyl cellulose were added to the filtrate. The mass of potassium sorbate was 0.2% of the mass of the obtained filtrate, and the mass of hydroxyethyl cellulose was obtained. 10% of the filtrate quality, evenly mixed, concentrated volume to 10% of the original volume, vacuum preservation of the finished essence.
实施例八Example eight
本实施例提供了一种护发精华液的制备方法,包括如下步骤:This embodiment provides a method for preparing a hair care essence, comprising the following steps:
S1:以重量份计,将80份百里香,15份何首乌,15份大豆籽,20份熟地黄,7份忍冬花,15份皂英,5份银杏叶,15份冰片和10份柠檬汁进行混合;S1: 80 parts of thyme, 15 parts of Polygonum, 15 parts of soybean seeds, 20 parts of Rehmannia glutinosa, 7 parts of honeysuckle, 15 parts of saponin, 5 parts of ginkgo leaves, 15 parts of borneol and 10 parts of lemon juice are used in parts by weight. mixing;
S2:在混合后的总重量为182份原料加入1820份乙醇水溶液中,其中乙醇水溶液中乙醇和水的体积比为1∶2,将混合物加热至85℃,搅拌均匀,保温2小时,再降温至常温;S2: The total weight after mixing is 182 parts of raw materials added to 1820 parts of aqueous ethanol solution, wherein the volume ratio of ethanol to water in the aqueous ethanol solution is 1:2, the mixture is heated to 85 ° C, stirred uniformly, kept for 2 hours, and then cooled. To normal temperature;
S3:将降温后的原料进行用120目筛进行过滤,得到滤液;S3: filtering the cooled raw material with a 120 mesh sieve to obtain a filtrate;
S4:在滤液中加入5份茶籽油、防腐剂山梨酸钾和乳化稳定剂羟乙基纤维素,山梨酸钾的质量为所得滤液质量的0.2%,羟乙基纤维素的质量为所得滤液质量的10%,混合均匀,浓缩体积至原体积的30%,真空保存得精华液成品。S4: 5 parts of tea seed oil, preservative potassium sorbate and emulsion stabilizer hydroxyethyl cellulose are added to the filtrate, the mass of potassium sorbate is 0.2% of the mass of the obtained filtrate, and the mass of the hydroxyethyl cellulose is the obtained filtrate. 10% of the mass, mix evenly, concentrate the volume to 30% of the original volume, and store the essence in vacuum.
实施例九Example nine
本实施例提供了一种护发精华液的制备方法,包括如下步骤:This embodiment provides a method for preparing a hair care essence, comprising the following steps:
S1:以重量份计,将100份百里香,25份何首乌,20份大豆籽,30份熟地黄,10份忍冬花,30份皂英,10份银杏叶,20份冰片和15份柠檬汁进行混合;S1: 100 parts by weight of thyme, 25 parts of Polygonum, 20 parts of soybean seeds, 30 parts of rehmannia root, 10 parts of honeysuckle, 30 parts of soap, 10 parts of ginkgo leaves, 20 parts of borneol and 15 parts of lemon juice. mixing;
S2:在混合后的总重量为250份原料加入2500份乙醇水溶液中,其中乙醇水溶液中乙醇和水的体积比为1∶2,将混合物加热至85℃,搅拌均匀,保温3小时,再降温至常温;S2: The total weight after mixing is 250 parts of raw materials added to 2500 parts of aqueous ethanol solution, wherein the volume ratio of ethanol to water in the aqueous ethanol solution is 1:2, the mixture is heated to 85 ° C, stirred uniformly, kept for 3 hours, and then cooled. To normal temperature;
S3:将降温后的原料进行用120目筛进行过滤,得到滤液; S3: filtering the cooled raw material with a 120 mesh sieve to obtain a filtrate;
S4:在滤液中加入8份茶籽油、蜂胶、防腐剂山梨酸钾和乳化稳定剂羟乙基纤维素,山梨酸钾的质量为所得滤液质量的0.2%,羟乙基纤维素的质量为所得滤液质量的10%,混合均匀,浓缩体积至原体积的30%,真空保存得精华液成品。S4: 8 parts of tea seed oil, propolis, preservative potassium sorbate and emulsion stabilizer hydroxyethyl cellulose were added to the filtrate. The mass of potassium sorbate was 0.2% of the mass of the obtained filtrate, and the mass of hydroxyethyl cellulose was 10% of the mass of the obtained filtrate, uniformly mixed, concentrated to 30% of the original volume, and stored in vacuum to obtain the finished essence.
实施例十Example ten
本实施例提供了一种护发精华液的制备方法,包括如下步骤:This embodiment provides a method for preparing a hair care essence, comprising the following steps:
S1:以重量份计,将90份百里香,20份何首乌,18份大豆籽,25份熟地黄,8份忍冬花,24份皂英,8份银杏叶,18份冰片和13份柠檬汁进行混合;S1: In parts by weight, 90 parts of thyme, 20 parts of Polygonum, 18 parts of soybean seeds, 25 parts of Rehmannia glutinosa, 8 parts of honeysuckle, 24 parts of saponin, 8 parts of ginkgo leaves, 18 parts of borneol and 13 parts of lemon juice mixing;
S2:在混合后的总重量为224份原料加入1800份乙醇水溶液中,其中乙醇水溶液中乙醇和水的体积比为2∶3,将混合物加热至65℃,搅拌均匀,保温3小时,再降温至常温;S2: The total weight after mixing is 224 parts of raw materials added to 1800 parts of aqueous ethanol solution, wherein the volume ratio of ethanol to water in the aqueous ethanol solution is 2:3, the mixture is heated to 65 ° C, stirred uniformly, kept for 3 hours, and then cooled. To normal temperature;
S3:将降温后的原料进行用100目筛进行过滤,得到滤液;S3: filtering the cooled raw material with a 100 mesh sieve to obtain a filtrate;
S4:在滤液中加入6份茶籽油、蜂胶、防腐剂山梨酸钾和乳化稳定剂羟乙基纤维素,山梨酸钾的质量为所得滤液质量的0.15%,羟乙基纤维素的质量为所得滤液质量的8%,混合均匀,浓缩体积至原体积的25%,真空保存得精华液成品。S4: 6 parts of tea seed oil, propolis, preservative potassium sorbate and emulsion stabilizer hydroxyethyl cellulose are added to the filtrate. The mass of potassium sorbate is 0.15% of the mass of the obtained filtrate, and the mass of hydroxyethyl cellulose is The 8% of the obtained filtrate was uniformly mixed, and the volume was concentrated to 25% of the original volume, and the finished essence was stored in a vacuum.
本发明实施例六至实施例十,通过以多种补血滋阴、养发乌发的中药材料为原料,提取其中有效成分,制备得到护发精华液,可以有效的促使头发变黑变密,从而更好的保护发部健康。本发明所述的护发精华液对头皮无害,用于生发乌发,疗效明显。In the sixth embodiment to the tenth embodiment of the present invention, the traditional Chinese medicine material for nourishing blood and nourishing the hair is used as a raw material, and the active ingredient is extracted to prepare the hair care essence liquid, which can effectively promote the hair to become black and dense. Thereby better protection of hair health. The hair care essence solution of the invention is harmless to the scalp, and is used for hair growth and hair growth, and the curative effect is obvious.
将本发明实施例六至实施例十制备的护发精华液进行药效学研究,并且以市面上某生发乌发精华液为对照组,具体的方法和结果如下:The hair care essence prepared by the sixth embodiment to the tenth embodiment of the present invention was studied for pharmacodynamics, and a hair-raising essence of the hair was used as a control group on the market. The specific methods and results are as follows:
1、对脱毛小鼠毛发再生的影响 1. Effect on hair regeneration in depilated mice
方法:将70只小鼠背部用硫化钡脱毛,脱毛面积为3cm×3cm,然后随机分为A、B、C、D、E、F、G七个组,每组10只。在小鼠背部脱毛皮肤规定区域内涂抹2ml相应的物质:A组涂抹实施例六制备得到的护发精华液,B组涂抹实施例七制备得到的护发精华液,C组涂抹实施例八制备得到的护发精华液,D组涂抹实施例九制备得到的护发精华液,E组涂抹实施例十制备得到的护发精华液,F组涂抹市面上某生发乌发精华液作为对照组,G组涂抹水作为对照组,每只小鼠每两天涂抹一次。METHODS: Seventy mice were depilated with barium sulfide, the hair removal area was 3 cm × 3 cm, and then randomly divided into seven groups of A, B, C, D, E, F, and G, with 10 in each group. Apply 2ml of the corresponding substance to the prescribed area of the skin of the back of the mouse: Group A is applied to the hair care essence prepared in Example 6, Group B is applied to the hair care essence prepared in Example 7, and Group C is applied to the preparation of Example 8. The obtained hair care essence solution, the group D was applied with the hair care essence prepared in the ninth embodiment, the group E was applied with the hair care essence prepared in the tenth embodiment, and the group F was applied with a hair-raising essence of the hair on the market as a control group. Group G smear was used as a control group, and each mouse was applied once every two days.
结果:一定时间后在各小鼠脱毛区,清数新生毛发的数量,并且随机取下20根新生毛发,用测微尺在显微镜下测其长度,求平均值,比较各组毛发生长差异。具体结果如下表1所示:RESULTS: After a certain period of time, the number of newborn hairs was counted in the depilated area of each mouse, and 20 new hairs were randomly taken. The length was measured under a microscope with a micrometer, and the average was compared to compare the hair growth differences of each group. The specific results are shown in Table 1 below:
表1使用精华液后各组小鼠毛发生长情况Table 1 Hair growth of mice in each group after using the essence
Figure PCTCN2017073130-appb-000001
Figure PCTCN2017073130-appb-000001
从上面的结果可知,在使用本发明的护发精华液后,各组小鼠毛发生长较 好,且随着使用时间的增长,效果越明显。在连续使用6个月后,E组的平均根数能达到89根,平均长度为90.75±13.64mm,比其他组的生长情况都好,尤其对于使用市面上某生发乌发精华液的F组,头发的平均根数仅能达到54根,平均长度仅为60.87±10.22mm。并且对比A-E组结果可知,E组(实施例十)制备的护发精华液效果更好。以上结果表明本发明制备的护发精华液可以滋养毛囊,促进毛发增生,有效的起到生发养发的作用。From the above results, it can be seen that after using the hair care essence of the present invention, the hair growth of each group of mice is relatively Ok, and as the usage time increases, the effect becomes more obvious. After 6 months of continuous use, the average number of roots in group E can reach 89, and the average length is 90.75±13.64mm, which is better than other groups, especially for group F using a hair-raising essence on the market. The average number of hairs can only reach 54 and the average length is only 60.87±10.22mm. And comparing the results of the A-E group, it can be seen that the hair care essence prepared by the E group (Example 10) is more effective. The above results show that the hair care essence prepared by the invention can nourish hair follicles, promote hair growth, and effectively play the role of hair growth and hair growth.
2、对受试人群头发颜色的影响2, the impact on the hair color of the test population
受试者选取标准和分组:选取长有较多白发的受试者280人,将其分为14组,分别是:30-40岁的男女各10人为A1组,30-40岁的男女各10人为B1组,30-40岁的男女各10人为C1组,30-40岁的男女各10人为D1组,30-40岁的男女各10人为E1组,30-40岁的男女各10人为F1组,30-40岁的男女各10人为G1组;40-50岁的男女各10人为A2组,40-50岁的男女各10人为B2组,40-50岁的男女各10人为C2组,40-50岁的男女各10人为D2组,40-50岁的男女各10人为E2组,40-500岁的男女各10人为F2组,40-50岁的男女各10人为G2组。Subject selection criteria and grouping: 280 subjects with more white hair were selected and divided into 14 groups: 30-40 for men and women, 10 for A1, 30-40 for men and women 10 people are B1, 10-40 for men and women are C1, 30-40 for men and women are D1, 30-40 for men and women are E1, 30-40 for men and women 10 In the F1 group, 10 males and 30s in 30-40 years old are in the G1 group; 10 men and women in 40-50 years old are in the A2 group, 10 men and women in the 40-50 age group are in the B2 group, and 10 in the 40-50 year old men and women are in the C2 group. In the group, 40 men and women of 40-50 years old are D2 group, 10 men and women of 40-50 years old are E2 group, 10 men and women of 40-500 years old are F2 group, and 10 men and women of 40-50 years old are G2 group.
试验产品和使用方法:所有受试者3天使用一次试验产品,且每次用量相同,均为2ml对应的产品:A组涂抹实施例六制备得到的护发精华液,B组涂抹实施例七制备得到的护发精华液,C组涂抹实施例八制备得到的护发精华液,D组涂抹实施例九制备得到的护发精华液,E组涂抹实施例十制备得到的护发精华液,F组涂抹市面上某生发乌发精华液作为对照组,G组涂抹水作为对照组,连续使用6个月。Test product and method of use: All subjects used the test product once every 3 days, and each time the same amount, 2 ml corresponding products: Group A applied the hair care essence prepared in Example 6, Group B applied Example 7 The hair care essence prepared by the preparation, the group C was applied to the hair care essence prepared in the eighth embodiment, the group D was applied to the hair care essence prepared in the ninth embodiment, and the group E was applied to the hair care essence prepared in the tenth embodiment. Group F smeared a hair-raising essence on the market as a control group, and group G applied water as a control group for 6 months.
结果:将受试者头部分为前、中、左、右、后五个区域,分别定位,各选取1cm2的标准点作为测量位置,取白头发根数的平均值。使用产品后,将所述区域的白头发根数按上述方法取得平均值,将使用产品后的白头发根数平均 值除以使用产品前的白头发根数平均值,算出白发变黑比例,再算出本组所有受试者的白发变黑比例平均值记录在下表,具体如表2所示:RESULTS: The heads of the subjects were divided into five regions: front, middle, left, right and back. They were respectively positioned. Each standard point of 1 cm2 was selected as the measurement position, and the average number of white hairs was taken. After using the product, the average number of white hairs in the area is averaged as described above, and the number of white hair roots after using the product is averaged. The value is divided by the average number of white hair roots before using the product, and the ratio of white hair to black is calculated. The average ratio of white hair blackening of all subjects in this group is recorded in the following table, as shown in Table 2:
表2使用精华液后各组受试者白发变黑比例情况Table 2 The proportion of white hair blackening in each group after using the essence
Figure PCTCN2017073130-appb-000002
Figure PCTCN2017073130-appb-000002
从上面的结果可知,在使用本发明的护发精华液后,各组受试者白发变黑比例,在连续使用6个月后,对于30-40岁的受试者来说,白发变黑比例为63%-76%,而使用市面上某生发乌发精华液,白发变黑比例仅为33%;对于40-50岁的受试者来说,白发变黑比例为57%-65%,而使用市面上某生发乌发精华液,白发变黑比例仅为27%。并且对比A-E组结果可知,E组(实施例十)制备的护发精华液效果更好。以上结果表明本发明制备的护发精华液可以滋养毛囊,促进毛发变黑,有效起到乌发养发的作用。From the above results, it can be seen that after using the hair care essence of the present invention, the gray-to-black ratio of the subjects in each group is white for a subject of 30-40 years after continuous use for 6 months. The ratio of blackening is 63%-76%, and the ratio of black hair to black is only 33% when using a hair styling essence on the market; for subjects 40-50 years old, the ratio of black hair to black is 57. %-65%, and using a hair-raising essence on the market, the ratio of white hair to black is only 27%. And comparing the results of the A-E group, it can be seen that the hair care essence prepared by the E group (Example 10) is more effective. The above results show that the hair care essence prepared by the invention can nourish the hair follicle, promote the blackening of the hair, and effectively play the role of raising hair.
3、对受试人群生发的影响3. Impact on the hair growth of the test population
受试者选取标准和分组:选取头发稀疏、部分脱落的受试者280人,将其分为14组,分别是:30-40岁的男女各10人为A1组,30-40岁的男女各10人为B1组,30-40岁的男女各10人为C1组,30-40岁的男女各10人为D1组,30-40岁的男女各10人为E1组,30-40岁的男女各10人为F1组,30-40岁的男女各10人为G1组;40-50岁的男女各10人为A2组,40-50岁的男女各10人为B2组,40-50岁的男女各10人为C2组,40-50岁的男女各10人为D2组,40-50岁的男女各10人为E2组,40-500岁的男女各10人为F2组,40-50岁的男女各10人为G2组。 Subject selection criteria and grouping: 280 subjects with sparse hair and partial shedding were selected and divided into 14 groups: 10-40 for men and women, A1 for men and women, 30-40 for men and women. 10 people are in the B1 group, 10-40 males and 30s are in the C1 group, 30-40 years old men and 10 each are in the D1 group, 30-40 years old men and women are 10 in the E1 group, and 30-40 years old in the men and women are 10 in the group In group F1, 10 males and 30s in 30-40 years old are G1 group; 10 men and women in 40-50 years old are A2 group, 10 men and women in 40-50 years old are B2 group, 10 men and women in 40-50 years old are C2 group. For 40-50 years old, 10 men and women are in D2 group, 40-50 years old men and 10 are E2 group, 40-500 year old men and 10 each are F2 group, and 40-50 year old men and women are 10 persons in G2 group.
试验产品和使用方法:所有受试者3天使用一次试验产品,且每次用量相同,均为2ml对应的产品:A组涂抹实施例六制备得到的护发精华液,B组涂抹实施例七制备得到的护发精华液,C组涂抹实施例八制备得到的护发精华液,D组涂抹实施例九制备得到的护发精华液,E组涂抹实施例十制备得到的护发精华液,F组涂抹市面上某生发乌发精华液作为对照组,G组涂抹水作为对照组,连续使用6个月。Test product and method of use: All subjects used the test product once every 3 days, and each time the same amount, 2 ml corresponding products: Group A applied the hair care essence prepared in Example 6, Group B applied Example 7 The hair care essence prepared by the preparation, the group C was applied to the hair care essence prepared in the eighth embodiment, the group D was applied to the hair care essence prepared in the ninth embodiment, and the group E was applied to the hair care essence prepared in the tenth embodiment. Group F smeared a hair-raising essence on the market as a control group, and group G applied water as a control group for 6 months.
结果:将受试者头部分为前、中、左、右、后五个区域,分别定位,各选取1cm2的标准点作为测量位置,取头发根数平均值。使用产品后,将所述区域的头发数按上述方法取得平均值,将使用产品后的头发根数平均值减去使用产品前的头发根数平均值,在除以使用产品前的头发根数平均值,算出头发数的增长比例,再算出本组所有受试者的头发数的增长比例平均值记录在下表,具体如表3所示:RESULTS: The heads of the subjects were divided into five regions: front, middle, left, right and back. They were respectively positioned. Each standard point of 1 cm2 was selected as the measurement position, and the average number of hair roots was taken. After using the product, the average number of hairs in the area is averaged as described above, and the average number of hair roots after using the product is subtracted from the average number of hair roots before use, and the number of hairs before being used is divided by the number of hairs before use. The average value, the growth ratio of the number of hairs was calculated, and the average growth rate of the hair number of all the subjects in the group was calculated in the following table, as shown in Table 3:
表3使用精华液前后各组受试者头发数的增长比例平均值情况Table 3 shows the average growth rate of hair of each group before and after using the essence
Figure PCTCN2017073130-appb-000003
Figure PCTCN2017073130-appb-000003
从上面的结果可知,在使用本发明的护发精华液后,头发数的增长比例较大,在连续使用6个月后,对于30-40岁的受试者来说,头发数的增长比例为149%-169%,而使用市面上某生发乌发精华液,头发数的增长比例仅为93%;对于40-50岁的受试者来说,头发数的增长比例为131%-147%,而使用市面上某生发乌发精华液,头发数的增长比例仅为82%。并且对比A-E组结果可知, 实施例十制备的护发精华液效果更好。以上结果表明本发明制备的护发精华液可以滋养毛囊,促进毛发增生,有效起到生发养发的作用。From the above results, it can be seen that after using the hair care essence of the present invention, the increase in the number of hairs is large, and the proportion of hair growth is increased for subjects aged 30-40 years after continuous use for 6 months. It is 149%-169%, and the growth rate of hair is only 93% when using a hair styling essence on the market; for a 40-50 year old, the growth rate of hair is 131%-147. %, and using a hair-raising essence on the market, the growth rate of hair is only 82%. And comparing the results of the A-E group, we can see that The hair care essence prepared in the tenth embodiment is more effective. The above results show that the hair care essence prepared by the invention can nourish the hair follicle, promote hair growth, and effectively play the role of hair growth and hair growth.
以上所述仅为本发明的优选实施例而已,并不用于限制本发明,对于本领域的技术人员来说,可根据智能清洁装置自身需要适当调整主板、散热模组的大体位置,也可根据产品实际热源状况,对散热模组和均温材料的位置及性能进行修改,以达到一种平衡状态。本发明可以有各种更改和变化。凡在本发明的精神和原则之内,所作的任何修改、等同替换、改进等,均应包含在本发明的权利要求范围之内。 The above description is only a preferred embodiment of the present invention, and is not intended to limit the present invention. For those skilled in the art, the general position of the main board and the heat dissipation module may be appropriately adjusted according to the needs of the smart cleaning device itself, or may be The actual heat source status of the product is modified to adjust the position and performance of the heat dissipation module and the temperature equalizing material to achieve a balanced state. The invention is capable of various modifications and changes. Any modifications, equivalent substitutions, improvements, etc. within the spirit and scope of the invention are intended to be included within the scope of the appended claims.

Claims (10)

  1. 一种护发精华液,其特征在于,其原料按重量份计包括:A hair care essence, characterized in that the raw materials thereof comprise, by weight:
    百里香50~120份,何首乌10~30份,大豆籽5~30份,熟地黄10~40份,甘草提取物5~15份,皂荚5~40份,银杏叶2~15份,冰片5~30份,柠檬汁5~20份和茶籽油3~10份。50 to 120 parts of thyme, 10 to 30 parts of Polygonum multiflorum, 5 to 30 parts of soybean seeds, 10 to 40 parts of Rehmannia glutinosa, 5 to 15 parts of licorice extract, 5 to 40 parts of acacia, 2 to 15 parts of ginkgo leaves, and 5 to 15 pieces of borneol 30 parts, 5-20 parts of lemon juice and 3-10 parts of tea seed oil.
  2. 根据权利要求1所述的护发精华液,其特征在于,其原料按重量份计包括:百里香80~100份,何首乌15~25份,大豆籽15~20份,熟地黄20~30份,甘草提取物7~10份,皂荚15~30份,银杏叶5~10份,冰片15~20份和柠檬汁10~15份,茶籽油5~8份。The hair care essence according to claim 1, wherein the raw material comprises, by weight, 80 to 100 parts of thyme, 15 to 25 parts of Polygonum multiflorum, 15 to 20 parts of soybean seeds, and 20 to 30 parts of rehmannia root. 7 to 10 parts of licorice extract, 15 to 30 parts of acacia, 5 to 10 parts of ginkgo leaves, 15 to 20 parts of borneol and 10 to 15 parts of lemon juice, and 5 to 8 parts of tea seed oil.
  3. 根据权利要求1所述的护发精华液,其特征在于,其原料按重量份计包括:百里香90份,何首乌20份,大豆籽18份,熟地黄25份,甘草提取物8份,皂荚24份,银杏叶8份,冰片18份和柠檬汁13份,茶籽油6份。The hair care essence according to claim 1, wherein the raw material comprises, by weight, 90 parts of thyme, 20 parts of Polygonum multiflorum, 18 parts of soybean seeds, 25 parts of Rehmannia glutinosa, 8 parts of licorice extract, and acacia 24 Serving, 8 parts of ginkgo leaves, 18 parts of borneol and 13 parts of lemon juice, and 6 parts of tea seed oil.
  4. 一种如权利要求1~3任一项所述的护发精华液的制备方法,其特征在于,将所述百里香、何首乌、大豆籽、熟地黄、甘草提取物、皂荚、银杏叶、冰片和柠檬汁按相应的重量份进行混合,得到混合后的原料;The method for preparing a hair care essence according to any one of claims 1 to 3, wherein the thyme, polygonum multiflorum, soybean seed, rehmannia root, licorice extract, acacia, ginkgo leaf, borneol and The lemon juice is mixed according to the corresponding parts by weight to obtain the mixed raw materials;
    将所述混合后的原料加入乙醇水溶液中,加热至60~80℃,搅拌均匀,保温2~4小时,再降温至常温;The mixed raw material is added to an aqueous ethanol solution, heated to 60-80 ° C, stirred uniformly, kept for 2 to 4 hours, and then cooled to room temperature;
    将所述降温后的原料进行过滤,得到滤液;The cooled raw material is filtered to obtain a filtrate;
    在所述滤液中加入相应重量份的所述茶籽油、蜂胶、防腐剂和乳化稳定剂,混合均匀,浓缩体积,真空保存得精华液成品。Adding the corresponding parts by weight of the tea seed oil, propolis, preservative and emulsion stabilizer to the filtrate, mixing uniformly, concentrating the volume, and preserving the finished liquid in a vacuum.
  5. 根据权利要求4所述的制备方法,其特征在于,所述混合后的原料与所述乙醇水溶液的质量比为1:8~1:15。 The preparation method according to claim 4, wherein a mass ratio of the mixed raw material to the aqueous ethanol solution is 1:8 to 1:15.
  6. 根据权利要求4所述的制备方法,其特征在于,所述乙醇水溶液中乙醇和水的体积比为1:2~2:1。The preparation method according to claim 4, wherein the ethanol aqueous solution has a volume ratio of ethanol to water of 1:2 to 2:1.
  7. 根据权利要求4所述的制备方法,其特征在于,所述过滤使用的是80~120目筛。The preparation method according to claim 4, wherein the filtration uses an 80-120 mesh sieve.
  8. 根据权利要求4所述的制备方法,其特征在于,所述防腐剂为山梨酸钾,所述山梨酸钾的质量为所述滤液的0.1%~0.2%。The preparation method according to claim 4, wherein the preservative is potassium sorbate, and the mass of the potassium sorbate is 0.1% to 0.2% of the filtrate.
  9. 根据权利要求4所述的制备方法,其特征在于,The preparation method according to claim 4, wherein
    所述乳化稳定剂为羟乙基纤维素,所述羟乙基纤维素的质量为所述滤液的2%~10%。The emulsion stabilizer is hydroxyethyl cellulose, and the mass of the hydroxyethyl cellulose is 2% to 10% of the filtrate.
  10. 根据权利要求4所述的制备方法,其特征在于,所述浓缩体积为浓缩至原体积的10~30%。 The preparation method according to claim 4, wherein the concentrated volume is concentrated to 10 to 30% of the original volume.
PCT/CN2017/073130 2017-02-08 2017-02-08 Hair care essence liquid and preparation method therefor WO2018145277A1 (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104622738A (en) * 2015-01-07 2015-05-20 安徽省华银茶油有限公司 Novel high-permeability tea seed oil liquid shampoo
CN106236652A (en) * 2016-08-29 2016-12-21 张悦辉 A kind of hair-care essence liquid and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104622738A (en) * 2015-01-07 2015-05-20 安徽省华银茶油有限公司 Novel high-permeability tea seed oil liquid shampoo
CN106236652A (en) * 2016-08-29 2016-12-21 张悦辉 A kind of hair-care essence liquid and preparation method thereof

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