WO2018090902A1 - 用于粉末填充的设备及方法 - Google Patents

用于粉末填充的设备及方法 Download PDF

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Publication number
WO2018090902A1
WO2018090902A1 PCT/CN2017/110876 CN2017110876W WO2018090902A1 WO 2018090902 A1 WO2018090902 A1 WO 2018090902A1 CN 2017110876 W CN2017110876 W CN 2017110876W WO 2018090902 A1 WO2018090902 A1 WO 2018090902A1
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WO
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Prior art keywords
powder
blister
crossbar
filling apparatus
powder filling
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PCT/CN2017/110876
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English (en)
French (fr)
Inventor
陈浩
Original Assignee
正大天晴药业集团股份有限公司
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Application filed by 正大天晴药业集团股份有限公司 filed Critical 正大天晴药业集团股份有限公司
Priority to CN201780064066.9A priority Critical patent/CN109982935B/zh
Publication of WO2018090902A1 publication Critical patent/WO2018090902A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B1/00—Packaging fluent solid material, e.g. powders, granular or loose fibrous material, loose masses of small articles, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B1/04—Methods of, or means for, filling the material into the containers or receptacles
    • B65B1/16—Methods of, or means for, filling the material into the containers or receptacles by pneumatic means, e.g. by suction

Definitions

  • the present application relates to an apparatus and method for uniform filling of powders, and more particularly to an apparatus and method for uniformly filling a powder into a blister of a blister package.
  • a blister pack to hold a powder medicament for an inhalation device, such as a powder mist inhaler for bronchodilator treatment.
  • a blister package typically includes a substrate on which are formed a plurality of blister, each blister being filled with a powder to be supplied by use of an inhalation device.
  • a cover sheet is formed by covering a cover sheet on a substrate having a blister filled with powder.
  • the powder particularly the pharmaceutical ingredient in the powder
  • Attachment of the drug to the substrate can result in inaccurate filling of the blister, causing stains, and can also cause problems in that the cover sheet cannot adhere to the substrate.
  • This filling method also requires a large powder storage container, which may result in waste of the drug.
  • an apparatus and a method for filling a blister strip with a powder are proposed in WO 2000071419 A by forming a plurality of containers with a perforated plate during filling, and forming a container in the holes
  • the medicine powder is quantitatively filled by the combination of the leveling blade and the wiping blade, and the containers are aligned with the blister on the substrate, so that the medicine powder filled in the container can be removed by the tool and accurately distributed into the blister, thereby avoiding The problem that the powder leaked to other areas of the substrate.
  • the flattening blade moves parallel to the surface of the perforated plate, scraping the powder lacking fluidity into the container, and applying a certain pressing force to the powder by flattening the plane and angle of the blade, the powder is applied. Press into the container and wipe the scraper off the excess powder above the container to ensure the same volume of powder in each container.
  • the blade moves in parallel along the perforated plate, and the surface thereof exerts a pressing force on the powder, so that the powder having poor fluidity is originally produced. It is easy to accumulate and squeeze agglomerate on the plane of the scraper, and the fluidity of the powder gradually deteriorates with the increase of the number of operations.
  • the drug component in the powder is unevenly distributed with the agglomeration of the powder, which affects the inside of the blister package. Bubble The content of the drug component in the hood is stable.
  • the prior art quantitative filling requires two operations using a leveling blade and a wiping blade, and requires reciprocal oscillation in the adjustment direction, which is cumbersome, complicated in structure, and low in efficiency.
  • the technical problem to be solved by the present invention is to provide an apparatus and method for powder filling to reduce or avoid one of the problems mentioned above.
  • the present invention provides a powder filling apparatus that can uniformly and efficiently fill a powder into a blister of a blister package.
  • the present invention proposes a powder filling apparatus for filling a powder into a blister of a blister package, wherein the powder filling apparatus includes a tank for containing the powder, and the bottom of the tank A plurality of holes are provided in alignment with the blister of the blister package, and at least one swing bar is disposed above the hole, and the swing bar reciprocates in the groove around the rotating shaft.
  • the swing bar includes a vertical rod whose upper end is vertically fixedly connected (eg, welded) on the rotating shaft, and a lower end of the vertical rod is fixedly connected (eg, welded) with a first cross arranged perpendicular to the vertical rod a rod, the first crossbar being parallel to the rotating shaft.
  • the swing lever is reciprocally oscillated by a fork provided at an end of the rotating shaft by a reciprocating telescopic rod.
  • the swing bar comprises two vertical bars.
  • the swing link further includes a second crossbar parallel to the first crossbar.
  • the second crossbar is directly fixedly coupled (eg, welded) to the vertical rod.
  • the second crossbar is fixedly connected (eg, welded) to the vertical rod by a first connecting rod, and the first connecting rod has a first angle with the vertical rod.
  • the second crossbar is fixedly connected (eg, welded) to the first crossbar by a second connecting rod, and the second connecting rod has a second angle with the vertical rod.
  • a bottom of each of the holes is provided with a vacuum suction port connected to the air suction device, and the vacuum air suction port is disposed within a range of the blister alignment of the blister package, the vacuum suction port
  • the surface is covered with a microporous membrane that blocks the passage of the powder.
  • the vacuum suction port is further connected with an air blowing device.
  • the powder filling device of the present application uses a pendulum rod connected to a vertical rod to agitate the powder to fill it into the blister, and the running route of the vertical rod and the cross rod is curved in the bottom of the groove, which can break up the powder, and
  • the outer surface of the crossbar and the vertical rod has a circular arc surface instead of a plane.
  • the powder can slide along the arc surface of the crossbar and the vertical rod, and there is no plane that can be stacked, so that no agglomeration is formed and no
  • the defect that causes uneven distribution of the drug components in the powder ensures that the components of the drug filled into each of the blister are uniform.
  • the present invention provides a method for filling a powder into a blister of a blister package comprising filling the powder into a blister of a blister package using the powder filling apparatus of the above aspect.
  • the powder filling method of the present application employs the powder filling apparatus having the structure described above, it is possible to avoid agglomeration and not cause defects in uneven distribution of the drug component in the powder, thereby ensuring filling of each bubble.
  • the pharmaceutical ingredients in the hood are uniform.
  • FIG. 1 is a schematic view showing the structure of a powder filling apparatus according to a specific embodiment of the present application
  • FIG 2 is a schematic view showing the structure of the swinging rod in the powder filling apparatus shown in Figure 1;
  • Figure 3 is a side cross-sectional view showing the operation of the powder filling apparatus shown in Figure 1;
  • FIG. 4 is a schematic structural view of a swing lever according to another embodiment of the present application.
  • Figure 5 is a side cross-sectional view showing the operation of the powder filling apparatus using the pendulum rod shown in Figure 4;
  • FIG. 6 is a schematic structural view of a swing lever according to still another embodiment of the present application.
  • Figure 7 is a side cross-sectional view showing the operation of the powder filling apparatus using the pendulum rod shown in Figure 6;
  • Figure 8 is a side cross-sectional view showing the operation of a powder filling apparatus incorporating the pendulum rods shown in Figures 2 and 6.
  • the present application provides a powder filling apparatus having an improved structure, which can be used to uniformly and efficiently fill a powder into a blister of a blister package, wherein the structure of the blister package and the blister are Known techniques in the pharmaceutical field are not described in detail, and blister packages and blisters are not shown in the drawings cited below.
  • FIG. 1 shows a schematic structural view of a powder filling apparatus according to a specific embodiment of the present application
  • the powder filling apparatus shown in FIG. 1 includes a tank 1 for accommodating powder, the bottom of the tank 1.
  • a plurality of holes 11 are arranged in alignment with the blister (not shown) of the blister package, and at least one pendulum rod 2 is disposed above the hole 11 (two pendulum rods are shown in the figure)
  • the pendulum rod 2 reciprocates in the groove 1 around a rotating shaft 21.
  • FIG. 2 is a schematic structural view of the swinging rod in the powder filling apparatus shown in FIG. 1;
  • FIG. 3 is a powder filling shown in FIG.
  • the side cross-sectional operation diagram of the device, as shown in FIG. 2-3, the swing rod 2 includes a vertical rod 211 vertically welded to the rotating shaft 21 at the upper end, and a lower end perpendicular to the vertical rod 211 is welded to the lower end of the vertical rod 211.
  • the rod 22, the first crossbar 22 is disposed parallel to the rotating shaft 21.
  • the powder filling device of the present invention uses the vertical rod 211 to connect the cross bar 22 to agitate the powder 9 so as to fill it into the blister, and the running route and the groove 1 of the vertical rod 211 and the cross rod 22
  • the bottom portion is curved, that is, the bottom of the vertical rod 211 and the height of the cross bar 22 from the bottom of the groove 1 are varied, so that the cross bar 22 forms an agitating effect on the powder during the swinging process (the vertical rod 211 also has a certain The agitation effect) can disperse the powder 9 and since the outer surface of the cross bar 22 and the vertical rod 211 has a circular arc surface instead of a plane, the powder can be along the circular arc surface of the cross bar 22 and the vertical rod 211 during the agitation process. Sliding, there is no plane that can be deposited, so that no agglomeration is formed, and there is no defect that causes uneven distribution of the drug components in the powder, and it is ensured that
  • the swing lever 2 shown in Figs. 1-2 includes two vertical rods 211.
  • the swinging lever 2 can be reciprocally oscillated by a shifting fork 212 provided at the end of the rotating shaft 21 by a reciprocating telescopic rod 8. That is, as shown in FIG. 1, the reciprocating telescopic rod 8 can be horizontally disposed perpendicular to the rotating shaft 21, and the reciprocating telescopic rod 8 corresponds to the shifting fork. 212 is provided with a lever 81, and the lever 81 is inserted into the slot of the fork 212. When the reciprocating rod 8 reciprocates, the lever 81 pushes the fork 212 to swing, thereby driving the shaft 21 to reciprocate, thereby driving the shaft 21 to be fixed. The connected rocker 2 swings back and forth in the groove 1.
  • the swing link 2 may further include a second crossbar 23 that is parallel to the first crossbar 22.
  • the second crossbar 23 can be directly welded to the vertical rod 211 (the second crossbar 23 is welded above the first crossbar 22, not shown).
  • the second crossbar 23 is welded to the first crossbar 22 by the first connecting rod 24.
  • the first connecting rod 24 and the vertical rod 211 have a first angle 25, and in FIGS. 2-3, the first angle 25 is 180 degrees.
  • FIG. 4-5 the second crossbar 23 is welded to the first crossbar 22 by the first connecting rod 24, and the first angle 25 is not a flat angle, but may be at other angles, such as an acute angle.
  • FIG. 4 shows a schematic structural view of a swing rod according to another embodiment of the present application
  • FIG. 5 shows a side sectional operation diagram of the powder filling apparatus using the swing rod shown in FIG. . 4-5 shows a structure in which the first angle 25 is set to be not a flat angle, which is advantageous for preventing the powder from being deposited on both sides of the groove, and the powder can be plucked from both sides by the second cross bar 23 at an oblique angle. In the middle, avoid uneven distribution of powder on the side.
  • the second crossbar 23 is welded to the vertical rod 211 by the second connecting rod 26, and the second connecting rod 26 has a second angle 27 between the vertical rod 211 and the vertical rod 211.
  • the second crossbar 23 disposed at an oblique angle can also pluck the powder from both sides to the middle to avoid uneven distribution of the side powder, which is advantageous for preventing the powder from being deposited on both sides of the groove.
  • first angle 25 shown in FIG. 5 and the second angle 27 shown in FIG. 7 are only for explaining the manner in which the second rail 23 is disposed at an oblique angle, which may be as shown in FIG. 5 and
  • the angle between the first and second connecting rods shown in FIG. 7 and the upper end of the vertical rod 211 may also be the complementary angle between the first and second connecting rods and the lower end of the vertical rod 211 or the extension line.
  • the size of the first angle 25 and the second angle 27 can be adjusted according to actual conditions, such as the depth of the powder, the width of the groove, the swing angle of the swing rod, and the like.
  • FIG. 8 shows the hybrid using the pendulum shown in FIGS. 2 and 6.
  • the powder can be drawn into each of the blister by vacuum pumping, so that the squeegee can be omitted from the prior art to avoid agglomeration.
  • a vacuum suction port (not shown) connected to the air suction device may be disposed at the bottom of each of the holes 11, and the vacuum air suction port is disposed in the range of the blister alignment of the blister package, and the vacuum pumping is performed.
  • the surface of the port is covered with a microporous membrane that blocks the passage of the powder.
  • the blister is sealed at the edge of the hole 11 and the air is metered into the blister by the air suction device, and the powder uniformly distributed in the groove 1 (including the sedimentation in the small hole 11) is transmitted through the hole 11 to the blister.
  • the vacuum pumping port is further connected with an air blowing device (the air blowing device may also be the same device as the air pumping device, and the device has both pumping and blowing functions. That is, every time the powder is filled, the air blower can be blown back to the vacuum suction port to blow away the powder in the hole 11 and the powder in the bubble is blocked by the microporous film. Inside the blister, it will not be blown back.

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
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  • Basic Packing Technique (AREA)
  • Supply Of Fluid Materials To The Packaging Location (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

一种粉末填充设备，用于将药粉（9）填充到泡罩包装件的泡罩中，该粉末填充设备包括容纳药粉（9）的槽（1），所述槽（1）的底部设置有与所述泡罩包装件的泡罩一一对准的多个孔洞（11），所述孔洞（11）的上方设置有至少一个摆杆（2），所述摆杆（2）绕转轴（21）在所述槽（1）中往复摆动。以及一种用于将药粉（9）填充到泡罩包装件的泡罩中的方法，所述方法包括使用粉末填充设备将所述药粉（9）填充到所述泡罩包装件的泡罩中。

Description

用于粉末填充的设备及方法 技术领域
本申请涉及一种用于粉末均匀填充的设备及方法，尤其是一种将药粉均匀填充到泡罩包装件的泡罩中的设备及方法。
背景技术
使用泡罩包装件为吸入装置盛装粉末药剂是公知的，例如支气管扩张治疗用的粉雾吸入器。这种泡罩包装件通常包括一块基片，在该基片上形成若干泡罩，每个泡罩中均充满待通过使用吸入装置而供应的药粉。把一块盖片盖在具有装满药粉的泡罩的基片上，便形成了泡罩包装件。
然而，在将药粉填充到泡罩中时可能会出现问题：粉末，特别是粉末中的药物成分，可能会附着在基片的外表面上，而不是进入泡罩包装件内。药物附着在基片上会导致泡罩填充的不精确，造成污迹，并且还可能造成盖片不能粘附在基片上的问题。这种填充方法还要求很大的药粉储存容器，可能导致药物的浪费。
为解决上述问题，WO 2000071419 A中提出了一种给泡罩条带填充药粉的设备及方法，其借助于在填充的过程中用一块带孔的板形成多个容器，在这些孔形成的容器中通过整平刮刀和檫拭刮刀的配合定量填充药粉，将这些容器与基片上的泡罩对准，即可以通过工具将容器中填充的药粉捅出并精确分配到泡罩中去，从而避免了药粉外漏到基片其它区域的问题。该现有技术中，整平刮刀平行于带孔的板的表面移动，将缺乏流动性的药粉刮入容器中，同时通过整平刮刀的平面和角度对药粉施加一定的挤压力，将药粉压入到容器中，檫拭刮刀将容器上方多余的药粉刮走，保证每个容器中的药粉容量相同。在该现有技术的利用整平刮刀和檫拭刮刀定量填充药粉的过程中，刮刀沿着带孔的板平行移动，其表面对药粉施加了挤压力，使得原本流动性就很差的药粉容易在刮刀的平面上堆积、挤压结块，药粉的流动性会随着操作次数的增加逐渐恶化，药粉中的药物成分随着药粉结块而分布不均，影响到泡罩包装件内的泡 罩中的药物成分的含量稳定性。另外，该现有技术定量填充时需要使用整平刮刀和檫拭刮刀两次操作，且需要调整方向往复摆动，步骤繁琐、结构复杂，效率较低。
发明内容
本发明要解决的技术问题是提供一种用于粉末填充的设备及方法，以减少或避免前面所提到的问题之一。
在一方面，本发明提供了一种粉末填充设备，其可以将药粉均匀高效地填充到泡罩包装件的泡罩中。
为解决上述技术问题，本发明提出了一种粉末填充设备，用于将药粉填充到泡罩包装件的泡罩中，其中，所述粉末填充设备包括一个容纳药粉的槽，所述槽的底部设置有与所述泡罩包装件的泡罩一一对准的多个孔洞，所述孔洞的上方设置有至少一个摆杆，所述摆杆绕转轴在所述槽中往复摆动。
优选地，所述摆杆包括上端垂直地固定连接(如焊接)在所述转轴上的竖杆，所述竖杆的下端固定连接(如焊接)有与所述竖杆垂直布置的第一横杆，所述第一横杆平行于所述转轴。
优选地，所述摆杆通过由往复伸缩杆驱动在所述转轴的端部设置的拨叉往复摆动。
优选地，所述摆杆包括两根竖杆。
优选地，所述摆杆进一步包括平行于所述第一横杆的第二横杆。
优选地，所述第二横杆直接固定连接(如焊接)在所述竖杆上。
优选地，所述第二横杆通过第一连接杆固定连接(如焊接)在所述竖杆上，所述第一连接杆与所述竖杆之间具有第一夹角。
优选地，所述第二横杆通过第二连接杆固定连接(如焊接)在第一横杆上，所述第二连接杆与所述竖杆之间具有第二夹角。
优选地，每个所述孔洞的底部均设置有一个连接抽气装置的真空抽气口，所述真空抽气口设置在所述泡罩包装件的泡罩对准的范围内，所述真空抽气口表面覆盖有阻挡所述药粉通过的微孔膜。
优选地，所述真空抽气口进一步连接有吹气装置。
本申请的粉末填充设备采用与竖杆连接的摆杆搅动药粉以将其填充到泡罩中，竖杆和横杆的运行路线与槽的底部呈弧线形，可以将药粉打散，且由于横杆以及竖杆的外形表面呈圆弧面而不是平面，搅动过程中药粉可以沿着横杆和竖杆的圆弧面滑动，不存在可以堆积的平面，因而不会形成结块，不存在导致药粉中的药物成分分布不均的缺陷，可以确保填充到每个泡罩中的药物成分都是均匀一致的。
在另一方面，本发明提供了一种用于将药粉填充到泡罩包装件的泡罩中的方法，其包括使用上述方面的粉末填充设备将药粉填充到泡罩包装件的泡罩中。
相应地，本申请的粉末填充方法由于采用了具有上文所述结构的粉末填充设备，因而可以避免结块，不会导致药粉中的药物成分分布不均的缺陷，进而确保填充到每个泡罩中的药物成分都是均匀一致的。
附图说明
以下附图仅旨在于对本发明做示意性说明和解释，并不限定本发明的范围。其中，
图1显示的是根据本申请的一个具体实施例的粉末填充设备的结构示意图；
图2显示的是图1所示粉末填充设备中的摆杆的结构示意图；
图3显示的是图1所示粉末填充设备的侧面剖视操作示意图；
图4显示的是根据本申请的另一个具体实施例的摆杆的结构示意图；
图5显示的是采用图4所示的摆杆的粉末填充设备的侧面剖视操作示意图；
图6显示的是根据本申请的又一个具体实施例的摆杆的结构示意图；
图7显示的是采用图6所示的摆杆的粉末填充设备的侧面剖视操作示意图；
图8显示的是混合采用图2和图6所示的摆杆的粉末填充设备的侧面剖视操作示意图。
具体实施方式
为了对本发明的技术特征、目的和效果有更加清楚的理解，现对照附图说明本发明的具体实施方式。其中，相同的部件采用相同的标号。
本申请提供了一种具有改进结构的粉末填充设备，所述粉末填充装置可用于将药粉均匀高效地填充到泡罩包装件的泡罩中，其中有关泡罩包装件以及泡罩的结构均为制药领域的公知技术，其结构不再一一赘述，且以下引用的附图中均未显示泡罩包装件及泡罩。
具体地，如图1所示，其显示的是根据本申请的一个具体实施例的粉末填充设备的结构示意图，图1中所示的粉末填充设备包括一个容纳药粉的槽1，槽1的底部设置有与所述泡罩包装件的泡罩(图中未示出)一一对准的多个孔洞11，孔洞11的上方设置有至少一个摆杆2(图中显示了两个摆杆2)，摆杆2绕一根转轴21在槽1中往复摆动。
摆杆2的结构及操作可以参见图2和图3，其中，图2显示的是图1所示的粉末填充设备中的摆杆的结构示意图；图3显示的是图1所示的粉末填充设备的侧面剖视操作示意图，如图2-3所示，摆杆2包括上端垂直焊接在转轴21上的竖杆211，竖杆211的下端焊接有一根与竖杆211垂直布置的第一横杆22，第一横杆22平行于转轴21设置。
由上可见，与现有技术不同，本发明的粉末填充设备采用竖杆211连接横杆22搅动药粉9，从而将其填充到泡罩中，竖杆211和横杆22的运行路线与槽1的底部呈弧线形，即竖杆211的底部和横杆22距离槽1的底部的高度是变化的，因而横杆22在摆动过程中对药粉形成了搅动效果(竖杆211也具有一定的搅动效果)，可以将药粉9打散，且由于横杆22以及竖杆211的外形表面呈圆弧面而不是平面，搅动过程中，药粉可以沿着横杆22和竖杆211的圆弧面滑动，不存在可以堆积的平面，因而不会形成结块，不存在导致药粉中的药物成分分布不均的缺陷，可以确保填充到每个泡罩中的药物成分都是均匀一致的。
进一步地，在一个具体实施例中，为了提高摆杆2的强度以及提高摆动的稳定性，图1-2中所示的摆杆2包括两根竖杆211。
在另一个具体实施例中，如图1所示，摆杆2可以通过一根往复伸缩杆8驱动转轴21的端部设置的拨叉212往复摆动。即，如图1所示，往复伸缩杆8可以垂直于转轴21水平设置，往复伸缩杆8上对应于拨叉 212设置有拨杆81，拨杆81插入拨叉212的槽口中，当往复伸缩杆8往复运动的时候，拨杆81推动拨叉212摆动，从而驱动转轴21往复转动，进而带动与转轴21固定连接的摆杆2在槽1中往复摆动。
进一步地，为了提高摆杆2的搅动和填充效率，在一个具体实施例中，摆杆2可以进一步包括一根平行于第一横杆22的第二横杆23。
其中，在一个具体实施例中，第二横杆23可以直接焊接在竖杆211上(第二横杆23焊接在第一横杆22的上方，图中未示出)。
或者也可以如图2-3所示，第二横杆23通过第一连接杆24焊接在第一横杆22上。对此，第一连接杆24与竖杆211之间具有一个第一夹角25，在图2-3中，第一夹角25为180度。
或者也可以如图4-5所示，第二横杆23通过第一连接杆24焊接在第一横杆22上，第一夹角25并不是平角，而是可以呈其它角度，例如锐角、直角或者钝角，其中，图4显示的是根据本申请的另一个具体实施例的摆杆的结构示意图；图5显示的是采用图4所示的摆杆的粉末填充设备的侧面剖视操作示意图。图4-5显示第一夹角25设置成不为平角的结构，这有利于防止药粉被拨到槽的两侧而堆积，可以利用倾斜角度的第二横杆23将药粉从两侧掏拨到中间，避免侧边药粉聚集分布不均。
或者，也可以如图6-7所示，第二横杆23通过第二连接杆26焊接在竖杆211上，第二连接杆26与竖杆211之间具有一个第二夹角27。同样地，如此设置的呈倾斜角度的第二横杆23也可以将药粉从两侧掏拨到中间，避免侧边药粉聚集分布不均，有利于防止药粉被拨到槽的两侧而堆积。
需要说明的是，图5中所示的第一夹角25以及图7中所示的第二夹角27只是为了说明第二横杆23呈倾斜角度布置的方式，其可以是如图5和7所示的第一、第二连接杆与竖杆211上端所夹的角度，也可以是第一、第二连接杆与竖杆211的下端或者延长线所夹的补角。另外，第一夹角25和第二夹角27的大小可根据实际情况调整，如药粉深度，槽宽度，摆杆的摆动角度等。
另外，在图8所示的实施例中，可以将前述的不同结构的摆杆2综合地设置在槽1中，其中，图8显示的是混合采用图2和图6所示的摆 杆的粉末填充设备的侧面剖视操作示意图，图8中可见，为了防止药粉被拨到槽的两侧而堆积，可以在两侧分别设置如图6所示的两个摆杆2，而槽1的中部不存在堆积的问题，因而中间设置的摆杆为图2所示的摆杆2。
进一步地，为了提高填充效率，在一个具体实施例中，药粉可以通过真空抽气的方式抽到各泡罩中去，因而相对现有技术可以省略檫拭刮刀而避免结块。具体地，可以在每个孔洞11的底部均设置一个连接抽气装置的真空抽气口(图中未示出)，真空抽气口设置在泡罩包装件的泡罩对准的范围内，真空抽气口表面覆盖有阻挡药粉通过的微孔膜。操作时，将泡罩对准孔洞11边缘密封，利用抽气装置朝泡罩内定量抽气，并将槽1中均匀分布(包括沉降在小孔11中)的药粉通过孔洞11传输至泡罩内。因为抽气口表面覆盖了微孔膜，可以阻断药粉但不能阻断空气，因而药粉不会被抽到真空抽气口里。另外，在又一个具体实施例中，为了避免孔洞11堵塞，真空抽气口进一步连接有吹气装置(吹气装置也可以与抽气装置是同一个装置，该装置兼具抽气和吹气功能即可)，每当药粉抽气填充完成之后，可以通过吹气装置向真空抽气口反向吹气，将孔洞11中的药粉吹走清空，而泡罩中的药粉则被微孔膜阻挡在泡罩内，不会被反向吹回。
本领域技术人员应当理解，虽然本发明是按照多个实施例的方式进行描述的，但是并非每个实施例仅包含一个独立的技术方案。说明书中如此叙述仅仅是为了清楚起见，本领域技术人员应当将说明书作为一个整体加以理解，并将各实施例中所涉及的技术方案看作是可以相互组合成不同实施例的方式来理解本发明的保护范围。
以上所述仅为本发明示意性的具体实施方式，并非用以限定本发明的范围。任何本领域的技术人员，在不脱离本发明的构思和原则的前提下所作的等同变化、修改与结合，均应属于本发明保护的范围。

Claims (11)

  1. 一种粉末填充设备，用于将药粉填充到泡罩包装件的泡罩中，其特征在于，所述粉末填充设备包括容纳药粉的槽(1)，所述槽(1)的底部设置有与所述泡罩包装件的泡罩一一对准的多个孔洞(11)，所述孔洞(11)的上方设置有至少一个摆杆(2)，所述摆杆(2)绕转轴(21)在所述槽(1)中往复摆动。
  2. 如权利要求1所述的粉末填充设备，其特征在于，所述摆杆(2)包括上端垂直固定连接在所述转轴(21)上的竖杆(211)，所述竖杆(211)的下端固定连接有与所述竖杆(211)垂直布置的第一横杆(22)，所述第一横杆(22)平行于所述转轴(21)。
  3. 如权利要求2所述的粉末填充设备，其特征在于，所述摆杆(2)包括两根竖杆(211)。
  4. 如权利要求2所述的粉末填充设备，其特征在于，所述摆杆(2)进一步包括平行于所述第一横杆(22)的第二横杆(23)。
  5. 如权利要求4所述的粉末填充设备，其特征在于，所述第二横杆(23)直接固定连接在所述竖杆(211)上。
  6. 如权利要求4所述的粉末填充设备，其特征在于，所述第二横杆(23)通过第一连接杆(24)固定连接在所述第一横杆(22)上，所述第一连接杆(24)与所述竖杆(211)之间具有第一夹角(25)。
  7. 如权利要求4所述的粉末填充设备，其特征在于，所述第二横杆(23)通过第二连接杆(26)固定连接在所述竖杆(211)上，所述第二连接杆(26)与所述竖杆(211)之间具有第二夹角(27)。
  8. 如权利要求2所述的粉末填充设备，其特征在于，所述摆杆(2)通过由往复伸缩杆(8)驱动在所述转轴(21)的端部设置的拨叉(212)往复摆动。
  9. 如权利要求1-8中任一项所述的粉末填充设备，其特征在于，每个所述孔洞(11)的底部均设置有连接抽气装置的真空抽气口，所述真空抽气口设置在所述泡罩包装件的泡罩对准的范围内，所述真空抽气口表面覆盖有阻挡所述药粉通过的微孔膜。
  10. 如权利要求9所述的粉末填充设备，其特征在于，所述真空抽气 口进一步连接有吹气装置。
  11. 用于将药粉填充到泡罩包装件的泡罩中的方法，其特征在于，使用权利要求1-10中任一项所述的粉末填充设备将所述药粉填充到所述泡罩包装件的泡罩中。
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