WO2018084598A1 - Procédé de production d'une plaque de protection pour chirurgie rachidienne - Google Patents
Procédé de production d'une plaque de protection pour chirurgie rachidienne Download PDFInfo
- Publication number
- WO2018084598A1 WO2018084598A1 PCT/KR2017/012328 KR2017012328W WO2018084598A1 WO 2018084598 A1 WO2018084598 A1 WO 2018084598A1 KR 2017012328 W KR2017012328 W KR 2017012328W WO 2018084598 A1 WO2018084598 A1 WO 2018084598A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- protective plate
- spinal surgery
- shape
- template
- manufacturing
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/148—Materials at least partially resorbable by the body
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y50/00—Data acquisition or data processing for additive manufacturing
- B33Y50/02—Data acquisition or data processing for additive manufacturing for controlling or regulating additive manufacturing processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B33—ADDITIVE MANUFACTURING TECHNOLOGY
- B33Y—ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3-D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3-D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING
- B33Y80/00—Products made by additive manufacturing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00526—Methods of manufacturing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2995/00—Properties of moulding materials, reinforcements, fillers, preformed parts or moulds
- B29K2995/0037—Other properties
- B29K2995/0059—Degradable
- B29K2995/006—Bio-degradable, e.g. bioabsorbable, bioresorbable or bioerodible
Definitions
- the present invention relates to a method of manufacturing a protective plate for spinal surgery, more specifically, a sufficient amount of protection while protecting the nerves exposed in the damaged or removed bone defects when the vertebrae are damaged or partly removed during spinal surgery
- the nerves in the vertebrae are exposed to the outside.
- the bone or similar materials for bone fusion are implanted for the reconstruction and fusion of the bone, which should be done while protecting the nerves exposed to the outside.
- vertebral bone graft surgery protects nerves by fixing a wide plate-shaped autogenous bone obtained from the hip bone of a patient to a structure such as a spinal rod, using a binding means such as thread or wire, and protecting the nerve.
- the implantation process was performed by additional implantation of bone grafts (BG) from the patient's hip bone.
- BG bone grafts
- the process of collecting and processing the autologous bone is complicated, and if the defect is large, there may be a problem in that the autologous bone of a sufficient size (a wide-bone autologous bone) cannot be secured.
- a vertebral bone graft was performed using a plate replacing the autologous bone in the form of a wide plate.
- a plate in the form of a plate is conventionally used.
- the plate of the upper graft is pressed by the force of the plate to press the plate to compress the nerves, thereby causing pain or paralysis. Since it could be caused, it was necessary to fix it by a strong fixing means made of hard metal so as to resist the pressing force.
- a protective plate for spinal surgery is made of polymer material and has a convex curved shape with an arcuate shape, it can be easily fixed in a non-fastening manner by being supported on a fixture so that both ends of the curved sheet do not spread. I can strongly support the force that the bone presses.
- it is also formed of a polymer material can solve the problem caused by artificial shading during CT or MRI imaging.
- the present invention is to propose a method that can be easily produced during the operation of the protective plate for spinal surgery as described above.
- an object of the present invention is to solve such a conventional problem, it is convex shape and can be fixed by being supported on the fixture so that both convex ends do not open, it is easy to install in a non-fastening manner and the plate is in contact with the nerves It is to provide a method of manufacturing a protective plate for spinal surgery that can be produced in a simple manner by a template having a convex or concave shape during the operation of the spinal surgical protective plate so as not to.
- the object of the present invention is a method of making a protective plate for spinal cord surgery used for implanting bone and similar bone union materials while protecting nerves exposed to damaged vertebrae or defects of vertebrae removed during surgery.
- a method of making a protective plate for spinal cord surgery used for implanting bone and similar bone union materials while protecting nerves exposed to damaged vertebrae or defects of vertebrae removed during surgery.
- the shape of the template may be a shape of a curved surface convex or concave in one direction.
- the shape of the template may be a shape in which a plurality of surfaces convex or concave bent in one direction are formed.
- the method may further include obtaining a spine image of the patient, and in step (a), the template may be prepared according to the characteristics of the affected part including the spine shape obtained by analyzing the image. have.
- the step (a) is the step of designing the template according to the characteristics of the affected area including the spine shape obtained by analyzing the image; And manufacturing the designed template with a 3D printer.
- the protective plate may be formed of a polymer.
- the protective plate may be formed of a bioabsorbable material.
- planar protective plate may be formed in a mesh structure.
- the flat protective plate may be manufactured by a 3D printer.
- the template may have a convex or concave curved shape even in a direction perpendicular to the one direction.
- the protective plate for spinal surgery is supported and fixed so that both convex ends are not extended to the structure formed around the vertebrae, it may further comprise the step of cutting the protective plate for spinal surgery according to the shape of the structure. .
- the flat protection plate may be heated using hot water in the step (b).
- the protection plate may be cooled using cold water.
- the manufacturing method of the protective plate for spinal surgery of the present invention as described above has the advantage that can be produced a protective plate for spinal surgery having a convex cross-section in a simple manner according to the spine shape and affected part of the patient during surgery.
- FIG. 1 is a perspective view of a protective plate for spinal surgery manufactured according to the present invention.
- Figure 2 is a perspective view for explaining the concept that the protection plate for spinal surgery produced according to the present invention is fixed to the affected part.
- FIG 3 is a perspective view showing a state in which the protective plate for spinal surgery of Figure 1 is fixed to the vertebrae.
- Figure 4 is a perspective view of the spinal cord surgical plate is separated in FIG.
- FIG. 5 is a flow chart of the manufacturing method of the protective plate for spinal surgery according to an embodiment of the present invention.
- FIG. 6 is a view sequentially showing a process according to FIG. 5.
- Figure 7 is a perspective view showing another form of the protective plate for spinal surgery produced in accordance with the present invention.
- FIG. 8 is a perspective view illustrating a state in which the protection plate for spinal surgery of FIG. 7 is fixed to the vertebrae.
- FIG. 9 is a perspective view showing another form of the protective plate for spinal surgery produced in accordance with the present invention.
- FIG. 1 is a perspective view of a protective plate for spinal surgery manufactured according to the present invention
- Figure 2 is a perspective view for explaining the concept that the protective plate for spinal surgery manufactured according to the present invention is fixed to the affected part
- Figure 3 is Figure 1
- Figure 4 is a perspective view showing the spinal surgery protection plate is fixed to the vertebrae
- Figure 4 is a perspective view of the spinal cord surgical protection plate is separated from FIG.
- Protective plate 100 for spinal surgery produced according to the present invention is to protect the nerves exposed to the defects of the vertebrae 200 during spinal surgery, the defects of the vertebrae 200 so that the nerves are not exposed to the outside
- the site is fixed to cover using the protective plate 100, and the bone fragments or similar bone fusion materials taken from the bone of the patient is implanted on the upper portion of the protective plate 100. That is, the protection plate 100 serves to protect the nerve tissue exposed by the bone graft or similar materials for bone union when performing the implantation process to obtain bone union while complementing the missing bone.
- Protective plate 100 for spinal surgery produced according to the invention is characterized in that it has a convexly curved shape in one direction as shown in FIG. At this time, the cross-sectional area convexly curved in the direction perpendicular to the longitudinal direction of the vertebrae 200 to surround the vertebrae 200 has an arcuate shape.
- the protective plate 100 may be formed in a mesh structure, as shown in Figure 1, by the mesh structure can prevent the graft bone to slide and move when the graft bone is implanted thereon, the grating
- the load-bearing performance can be improved by adjusting the spacing between them and the thickness of the grid.
- the protection plate 100 for spinal surgery produced according to the present invention can be fixed to surround the vertebrae 200 in a non-fastening manner without a separate fastening means. Since the shape of the protective plate 100 is convex upwardly convex, if the protective plate 100 can be supported so as not to be unfolded by a load pressed from above by the graft bone, the protective plate 100 is a defective portion of the vertebrae 200. Can be fixed at
- FIG. 2 is a diagram illustrating this concept, by which both ends of the protection plate 100 are supported by the fixtures 170 formed on the left and right sides of the convexly curved protection plate 100 so that the protection plate 100 is additionally fastened. It can be fixed stably without.
- a spinal screw 115 which is used for fixing the spine, may be used, which will be described later with reference to FIG. 3.
- the protective plate 100 When the protective plate 100 is formed in a flat shape, it must be strongly fixed with a hard material to support the load by the upper graft bone. However, if the cross section, such as the protective plate 100 of the present invention has a curved shape convex upward convex, the curved plate 100 will not be able to be unfolded if it only resists the force pushing to the side in the direction to be unfolded. That is, if it can only resist the force to be extended to the side can be structurally strong resistance to the force pressing the plate 100 by the graft. As described above, the flat plate has to be fixed with a strong tension to resist the force pushed by the graft bone from the top, but as shown in FIG. 1, the convex plate 100 may resist the pushing force to the side. With enough support, you can resist the pressure from the top. This simplifies the surgical process and dramatically shortens the operation time.
- spinal fixation screws 115 are often used on both sides, and the spinal fixation screws 115 may support the protective plate 100 on both sides.
- both ends of the protective plate 100 which is bent upwardly convex in the neck of the spinal fixing screw 115 may be positioned so that the protective plate 100 may not be extended from side to side. Since both ends of the protective plate 110, which are convex and curved upward, are supported by contact with a neck of the spinal fixing screw 115, the protective plate 100 can be easily fixed to the affected part.
- the protection plate 100 is bent upwardly convex, when the protection plate 100 is fixed as shown in FIG. 3, spaces between the nerves covered by the protection plate 100 and the protection plate 100 may be formed. There is a number. Therefore, the protective plate 100 does not touch the nerve during spinal surgery, so the protective effect of the nerve is excellent.
- the protection plate 110 is supported by a neck just below the head of the spinal screw 115, but in some cases, the spinal screw 115 is located below the spinal screw 115.
- the protection plate 110 may be supported on the body portion of the body, or may be supported by the spinal rod 110.
- the neck of the spinal fixing screw 115 is attached to the protective plate 100 as shown in FIG. 4 so as to further strengthen the fixing force.
- the groove 105 may be formed at a predetermined position corresponding to the spinal screw 115 at both ends of the protective plate 100 so as to surround the protective plate 100. Therefore, since the groove 105 of the protective plate 100 is inserted into and inserted into the neck of the spinal screw 115, the fixing force of the protective plate 100 can be further strengthened.
- the fixing plate 100 is fixed by supporting both ends of the protection plate 100 using the spinal fixing screw 115, but a separate screw, nail, and spike are described.
- Fixing device 170 such as back to the vertebrae to support both ends of the protective plate 100 by using it to secure the protective plate 100, the protruding portion of the bone formed around the protective plate (
- the protection plate 100 may be fixed by supporting both ends of the 100.
- FIG 5 is a flow chart of a method of manufacturing a protective plate for spinal surgery according to an embodiment of the present invention
- Figure 6 is a view showing the process according to Figure 5 in sequence
- Figure 7 is a spinal surgery produced according to the present invention
- Figure 8 is a perspective view showing another form of the protective plate
- Figure 8 is a perspective view showing a state in which the protective plate of the spinal surgery of Figure 7 fixed to the vertebrae
- Figure 9 is a protective plate for spinal surgery produced according to the present invention It is a perspective view which shows another form of.
- Method of manufacturing a protective plate for spinal surgery comprises the step of preparing a template 500 (S310), heating the flat plate (100a) (S320), heated protective plate (100a) ) May be included in the template 500 to be deformed (S330), and to cool the deformed protective plate 100 (S340).
- cutting the protection plate 100 may further include a step (S350).
- Template 500 may be prepared in various forms in advance according to the size of the protective plate 100, the shape of the curved surface to be made in advance to select the appropriate template 500 according to the characteristics of the affected part, but in the present invention It can be produced considering the characteristics of the affected area directly during surgery.
- the characteristic of the affected part may mean the shape of the spine 200 of the patient, the location of the affected part, the size of the affected part, and the like.
- the patient's spine 200 can be acquired by using a medical imaging device and analyzed to determine characteristics of the patient's own spine 200, and information about the location of the affected part and the size of the affected part can also be identified. .
- the protective plate 100 for spinal surgery in which the size, curvature, etc. of the protective plate is reflected. Can be designed in 3D.
- a template having a curved surface corresponding to the shape of the designed protective plate in 3D it is possible to produce a custom template directly during surgery using a 3D printer according to the 3D design.
- the flat plate protection plate (100a) is heated to increase the ductility to facilitate the deformation of the shape (S320).
- Protective plate 100 for spinal surgery may be made of a non-metallic material containing a polymer.
- MRI computed tomography
- MRI magnetic resonance imaging
- the protective plate 100 according to the present invention may be formed of a bioabsorbable material such as PCA, PVA, PDS, PLA, PDA, PLDLA.
- the protective plate 100 When formed of a polymer material can be easily cut with a surgical scissors, it is possible to cut the protective plate 100 according to the size of the surgical site during surgery. Therefore, as described above with reference to Figure 4, when fixing the protective plate 100 to the surgical site, the groove 105 for inserting the neck of the spinal fixing screw 115 is to determine the position during surgery for surgery It may be formed by cutting with scissors. This will be described later.
- a mesh structure may be formed on the flat protective plate 100a as shown in FIG. 6.
- the spacing, size and shape of the mesh can be adjusted as described above.
- the flat protective plate 100a including the mesh structure can also be manufactured using a 3D printer (not shown) during surgery.
- a 3D printer not shown
- the back can be designed and manufactured directly at the surgery site.
- the flat plate type protection plate 100a is not limited to being manufactured and prepared directly during surgery using a 3D printer (not shown), and may be prepared in advance by various known methods.
- the protective plate 100 is formed of a polymer material in the present invention
- the hot water 410 may be used as a method of heating the flat plate-shaped protection plate 100a, but is not limited thereto.
- the flat plate type protection plate 100a may be dipped in a warm water 410 heated at an appropriate temperature for a predetermined time, as shown in FIG. 6.
- the temperature of the hot water 410 it is important to control the temperature of the hot water 410, if the temperature of heating the plate-type protection plate 100a is too high, the ductility of the plate-type protection plate 100a becomes too large to handle, and if too low deformation is It may not happen easily.
- the temperature can be changed according to the material of the polymer, etc., when the production using the PCL (Poly-Caprolactone), the experimental results showed that the optimum results in the range of 55 °C ⁇ 60 °C.
- the protection plate 100a which is heated and ductile, is seated on the template 500 having the prepared curved surface, thereby deforming the shape of the protection plate 100a according to the shape of the template 500 (S330).
- the shape of the template 500 may be a shape convexly curved in one direction as shown in FIG. 6, but is not limited thereto.
- the shape of the protective plate 100 can be easily deformed according to the shape of the template 500. have.
- the heated protective plate 100a is seated on the template 500 to cool and deform the protective plate 100 in a state where the shape of the protective plate 100 is deformed according to the shape of the template 500.
- the shape can be maintained (S340).
- the protection plate 100 may be exposed to the atmosphere to use natural cooling.
- the cold water 420 or cold water 420 is supplied to the template 500 while the protection plate 100 is seated. ), The protection plate 100 can be cooled.
- Cooling the deformed protective plate 100 in the state seated on the template 500 as described above to maintain the deformed shape, by using the protective plate 100 in the neck of the spinal fixing screw 115 as shown in FIG. ) Can be easily fixed in a non-fastening way.
- a hole 105 into which the neck is inserted may be formed in the protection plate 100 so as to further strengthen the fixing force (S350). Therefore, in consideration of the position to be mounted on the surgical site, the hole 105 can be formed by cutting using surgical scissors during surgery.
- FIGS. 5 and 6 is a method of manufacturing a protective plate for spinal surgery according to an embodiment of the present invention described above with reference to FIGS. 5 and 6 can be simply made during the operation, can be actively produced during the operation according to the characteristics of the affected part of the patient .
- the protection plate 100 for spinal surgery manufactured according to the present invention is convexly curved in a direction perpendicular to the longitudinal direction of the vertebrae 200 and at the same time in the longitudinal direction of the vertebrae 200. It may also be formed to be convexly curved. That is, the rectangular flat plate-shaped protection plate 100a may be convexly curved in the horizontal and vertical directions, respectively. In this case, as shown in FIG. 8, a space formed between the vertebrae 200 and the convex bent protection plate 100 in the longitudinal direction of the spine may prevent foreign substances from entering during surgery. As convexly curved, the features that can strongly support the load on the top and the features that can be easily fixed in a non-fastening manner are the same as the above.
- the protective plate 100 for spinal surgery in the present invention, simply preparing a template 500 to correspond to the shape of the protective plate 100 of FIG. 7, the protective plate 100 for spinal surgery according to the present invention by the method described with reference to FIGS. 5 and 6. Can be produced. Therefore, in the present invention, the protection plate 100 for spinal surgery of various shapes can be manufactured during surgery without being limited to the above-described shape.
- the protective plate 100 is a spine of the quadrangular surface so that the convex cross-section is convex polygonal shape It may be a shape bent in the plural in the longitudinal direction of the bone 200. Accordingly, by preparing a template 500 having a shape in which a plurality of curved surfaces are formed in one concave or convex shape corresponding to the shape of FIG. 9, and for the spinal surgery of FIG. 9 by the method described with reference to FIGS. 5 and 6.
- the protective plate 100 can be manufactured.
Abstract
La présente invention concerne un procédé de fabrication d'une plaque de protection pour chirurgie de la moelle épinière, qui est utilisée pour protéger des nerfs exposés à partir d'une vertèbre endommagée ou de la partie manquante d'une vertèbre retirée pendant une intervention chirurgicale. Le procédé de production d'une plaque de protection pour chirurgie rachidienne, selon la présente invention, comprend les étapes consistant à : (a) préparer une plaque de protection plate ; (b) chauffer la plaque de protection pour avoir une ductilité accrue ; (c) placer la plaque de protection chauffée sur un gabarit ayant une surface incurvée, et transformer celle-ci en la forme du gabarit ; et (d) refroidir la plaque de protection pour maintenir la forme transformée courbée de manière convexe.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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KR1020160146630A KR101882097B1 (ko) | 2016-11-04 | 2016-11-04 | 척추 수술용 보호 플레이트의 제작방법 |
KR10-2016-0146630 | 2016-11-04 |
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WO2018084598A1 true WO2018084598A1 (fr) | 2018-05-11 |
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PCT/KR2017/012328 WO2018084598A1 (fr) | 2016-11-04 | 2017-11-02 | Procédé de production d'une plaque de protection pour chirurgie rachidienne |
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KR (1) | KR101882097B1 (fr) |
WO (1) | WO2018084598A1 (fr) |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2008539875A (ja) * | 2005-05-03 | 2008-11-20 | エイ. ウィリアムズ、リットン | 骨結合式外科メッシュ |
KR20110035214A (ko) * | 2009-09-30 | 2011-04-06 | 전남대학교산학협력단 | 영상기반의 환자 맞춤 의료형 척추 수술 방법 및 척추 보형물 |
KR20110087863A (ko) * | 2010-01-27 | 2011-08-03 | 주식회사 솔고 바이오메디칼 | 척추질환의 수술을 위한 플레이트 |
KR20150087788A (ko) * | 2014-01-22 | 2015-07-30 | 백정환 | 환자 맞춤형 보형물 제작 방법 |
KR101665243B1 (ko) * | 2015-04-02 | 2016-10-25 | 순천향대학교 산학협력단 | 척추수술용 브라켓 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR200410476Y1 (ko) | 2005-12-21 | 2006-03-07 | (주)베리안 | 척추경 나사못 |
-
2016
- 2016-11-04 KR KR1020160146630A patent/KR101882097B1/ko active IP Right Grant
-
2017
- 2017-11-02 WO PCT/KR2017/012328 patent/WO2018084598A1/fr active Application Filing
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2008539875A (ja) * | 2005-05-03 | 2008-11-20 | エイ. ウィリアムズ、リットン | 骨結合式外科メッシュ |
KR20110035214A (ko) * | 2009-09-30 | 2011-04-06 | 전남대학교산학협력단 | 영상기반의 환자 맞춤 의료형 척추 수술 방법 및 척추 보형물 |
KR20110087863A (ko) * | 2010-01-27 | 2011-08-03 | 주식회사 솔고 바이오메디칼 | 척추질환의 수술을 위한 플레이트 |
KR20150087788A (ko) * | 2014-01-22 | 2015-07-30 | 백정환 | 환자 맞춤형 보형물 제작 방법 |
KR101665243B1 (ko) * | 2015-04-02 | 2016-10-25 | 순천향대학교 산학협력단 | 척추수술용 브라켓 |
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Publication number | Publication date |
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KR101882097B1 (ko) | 2018-07-27 |
KR20180050458A (ko) | 2018-05-15 |
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