Classifications

• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
  • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
  • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • B01L3/02—Burettes; Pipettes
  • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
  • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
  • B01L3/0227—Details of motor drive means
• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
  • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
  • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • B01L3/02—Burettes; Pipettes
  • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
  • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
  • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
  • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
  • B01L3/56—Labware specially adapted for transferring fluids
  • B01L3/565—Seals
• • G—PHYSICS
  • G01—MEASURING; TESTING
  • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
  • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
  • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
  • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
  • G01N35/1016—Control of the volume dispensed or introduced
• • H—ELECTRICITY
  • H01—ELECTRIC ELEMENTS
  • H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
  • H01F7/00—Magnets
  • H01F7/06—Electromagnets; Actuators including electromagnets
  • H01F7/08—Electromagnets; Actuators including electromagnets with armatures
  • H01F7/16—Rectilinearly-movable armatures
  • H01F7/1607—Armatures entering the winding
  • H01F7/1615—Armatures or stationary parts of magnetic circuit having permanent magnet
• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
  • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
  • B01L2300/00—Additional constructional details
  • B01L2300/08—Geometry, shape and general structure
  • B01L2300/0803—Disc shape
• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
  • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
  • B01L2300/00—Additional constructional details
  • B01L2300/08—Geometry, shape and general structure
  • B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
• • B—PERFORMING OPERATIONS; TRANSPORTING
  • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
  • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
  • B01L2400/00—Moving or stopping fluids
  • B01L2400/04—Moving fluids with specific forces or mechanical means
  • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
  • B01L2400/043—Moving fluids with specific forces or mechanical means specific forces magnetic forces
• • H—ELECTRICITY
  • H01—ELECTRIC ELEMENTS
  • H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
  • H01F7/00—Magnets
  • H01F7/02—Permanent magnets [PM]

Definitions

• Permanent magnet assemblies receiving exoskeleton for a
• the present invention relates to a permanent-magnetic piston assembly for a pipetting device, wherein the piston assembly extends along a piston axis and has a plurality of Pernnanentnanmagnetanssenen which are arranged along the piston axis in such alternately opposite polarization direction one behind the other, that for each two along the piston axis immediately following one another Permanent magnet arrangements applies, which are the same along the piston axis nearest magnetic poles of different consecutive permanent magnet arrangements of the same name.
• a generic piston assembly is known from WO 201 1/083125.
• This prior art document teaches arranging the permanent magnet arrays of alternately opposite polarization to generate a high gradient magnetic field along the piston axis where identical poles of different magnet arrays face each other, thereby detecting the position detection of the piston assembly in a guide tube of a magnetic pipetting device.
• field-based sensors facilitates or increases the accuracy of detection.
• This structural design of the piston assembly has the advantage that the individual permanent magnets can form a radial outer side of the piston assembly, and thus a radial gap between the perma tations relative to the piston axis. Magnetic magnets and an outer, the piston assembly for movement driving magnetic field can be kept small, which increases the effectiveness of a magnetic motion drive.
• the hollow cylindrical permanent magnets form a weaker magnetic field compared to solid permanent magnets of the same external dimensions due to the lack of central mass.
• a permanent magnetic piston assembly of the type mentioned above, which comprises a longitudinally extending along the piston axis as a tube axis cladding tube, in which the plurality is received in permanent magnet arrangements.
• the outer contour of the cladding tube can also determine the outer contour of the piston subassembly. Even if the cladding tube has the same mass as a carrier rod fixing an equally long plurality of permanent magnet arrangements, the cladding tube is due to the larger radial distance. tion of their mass from the piston axis with the same force less deformable. The area moment of inertia of the cladding tube is considerably larger than for a carrier bar of the same mass, even with a thin design of the tube wall for bending around any bending axis orthogonal to the piston axis.
• any arrangement having one or more permanent magnets forming a north pole and a south pole applies as a "permanent magnet arrangement".
• the permanent magnet arrangement can be formed from a plurality of individual permanent magnets, which are provided with the same polarity in succession. This can be advantageous for manufacturing considerations.
• a permanent magnet arrangement preferably comprises exactly one permanent magnet in order to minimize the number of components which are necessary for producing the permanent-magnetic piston assembly.
• the plurality of permanent magnet arrangements preferably comprises a plurality of permanent magnets, and more preferably the number of permanent magnets is equal to the number of permanent magnet arrangements.
• the permanent magnets no longer necessarily have to be glued together. This facilitates the assembly of the piston assembly.
• they can be connected to the cladding tube by adhesive. For this purpose, however, it is sufficient to provide the radially inwardly facing wall of the cladding tube and / or the lateral surface of cylindrical or prismatic permanent magnets with adhesive and then to spend the permanent magnets in the cladding tube. It is also possible lent to secure the permanent magnets after being placed in the cladding with potting compound in position.
• potting compound is less preferred because due to advantageously low gaps a very low-viscosity potting compound must be used in the shipment or possibly the gap must be increased so that the potting compound can penetrate into the radial gap between the cladding tube and permanent magnets.
• adhesive which can be applied even in very thin films, is therefore preferred.
• a soft-magnetic separating body is arranged between two permanent magnet arrangements directly following one another along the piston axis, with the poles of the same name facing one another.
• the material of the soft magnetic separator may be a ferromagnetic or ferrimagnetic material. It is preferably ferromagnetic.
• soft magnetic, d. H. magnetizable but not permanently magnetized material such as iron, nickel and their magnetizable alloys
• soft magnetic, d. H. magnetizable but not permanently magnetized material such as iron, nickel and their magnetizable alloys
• magnetic-field-sensitive sensors such as Hall sensors
• an axially narrow separating body is sufficient, so that the at least one soft-magnetic separating body is preferably a disc-shaped separating body whose mean radial dimension orthogonal to the piston axis is greater than its mean axial dimension along the piston axis.
• the disc-shaped separating body may be formed as a flat cylinder whose radial dimension from the piston axis to its radial
• the outermost edge can be twice or even five times larger than its axial dimension, or even more than five times as large. If the separating body does not have a constant radial dimension in the circumferential direction, but its radial dimension is location-dependent, the mean radial dimension is to be determined as the average value of all radial dimensions along the circumference over a representative circumferential section.
• the axial dimension wherein the separating body preferably has parallel and mutually parallel end faces and between these has a circular cylindrical outer surface which connects the end faces.
• the separating body may be an annular disc-shaped separating body, with a central axially continuous recess, the use of solid separating bodies is preferred.
• a soft-magnetic separating body is provided between each joint of the piston assembly, on which identical poles of different permanent magnet arrangements follow one another in the axial direction.
• the at least one soft magnetic separator is connected to the cladding tube by adhesive or potting compound.
• the permanent magnets as well as the separating body are adhesively connected only to the cladding tube, but not with each other, which allows a maximum axial approach of the permanent magnet arrangements to each other or to a separating body.
• the separating body preferably has the same shape on its outer circumference as a permanent magnet located axially adjacent to it.
• all permanent magnet arrangements or permanent magnets of the piston assembly at least on its outer circumference the same shape, for reasons of simplified production, the permanent magnets used in a piston assembly are particularly preferred identical and thus the same design.
• the separating bodies thus do not differ in their outer peripheral shape preferably from the permanent magnet arrangements and are different from these only with regard to the material used for their formation and with respect to their axial length.
• separating bodies and / or permanent magnet arrangements can have any desired shape fitting into the respective cladding tube, ie they can be prismatic or cylindrical, preferably prismatic or circular cylindrical.
• both the permanent magnet arrangements and the separating bodies are solid.
• the permanent magnet arrangements and / or the separating body are formed on its outer circumference complementary to the shape of the inner wall of the cladding tube.
• "complementary" should in particular include that case in which the radial gap formed between a permanent magnet or / and a separating body and the radially opposite inner wall section is substantially constant along a revolution about the piston axis. This preferably applies to all orthogonal to the piston axis cross-sections.
• piston assembly For effective aspiration and dispensing of liquids by a pipetting device using the presently discussed piston assembly, it is necessary that the piston assembly is sealed or at least sealable to a guide tube of a pipetting device surrounding it radially outwardly. This can be achieved for example by a liquid, in particular viscous, sliding film on the outside of the cladding tube, wherein such a sealing film can also have a friction-reducing effect.
• a liquid, in particular viscous, sliding film on the outside of the cladding tube, wherein such a sealing film can also have a friction-reducing effect.
• the use of such a "sealing film" between piston assembly and guide tube entails the risk of contamination of the liquid to be pipetted, since it can not be excluded that at least traces of the sealing liquid from the cylinder of the Piston assembly forming guide tube can get into the respective pipette tip.
• the piston assembly of the present invention preferably has a seal assembly connected to it for co-movement with the cladding tube at an axial longitudinal end, which will hereinafter be referred to as a "seal-lengthend".
• This seal assembly is a solid state seal assembly.
• the longitudinal seal end is preferably the longitudinal end closest to the pipetting tip of a pipetting device.
• the sealing arrangement preferably has a sealing section running axially away from the cladding tube, which protrudes radially over the cladding tube at least in an axial section, so that the cladding tube is under formation a radial gap with the surrounding guide tube (cylinder) of the pipetting device can be inserted into this.
• the radial gap can be bridged between the jacket tube and the guide tube, and thus the piston arrangement can be sealed off from the guide tube.
• the radially projecting radially over the cladding tube extending in the circumferential direction advantageously completely around the piston construction axis, so that in the assembled state of the sealing portion can be along a circumferential around the piston axis ring band in contact with the guide tube.
• the sealing portion has a sleeve formation projecting away from the jacket tube, on which the axial portion projecting radially beyond the jacket tube is formed.
• the sealing portion may have a bell-shaped shape when viewed in longitudinal section.
• the radially inner recess of the sleeve formation may be simply circular-cylindrical or, in the case of an injection molding production of the sealing arrangement, be widened away from the cladding tube, in particular in a conically widening manner.
• connection of the sealing arrangement with the cladding tube can be realized in a simple manner in that the sealing arrangement has a connecting portion which projects axially into the cladding tube and is connected to the cladding tube.
• the connecting portion may have radially outward an engagement force-increasing contour, such as a SAge leopardkontur with differently sloped flanks such that insertion of the connecting portion into the cladding tube with less force is achieved than a withdrawal of the connecting portion of the cladding tube in the opposite direction.
• the connecting portion may be fixed with adhesive and / or potting compound on the cladding tube.
• connection section on the cladding tube clamping force holding the connecting portion in an axial region preferably in an axially adjacent to the sleeve formation axial portion
• the central recess may preferably have a thread, so that a mounting tool is temporarily attachable to the connecting portion.
• a clamping plug can be inserted into the central recess to increase under elastic radial deformation of the connecting portion between the connecting portion and the surrounding Hüllrohrabrough surrounding clamping force.
• the centering component does not necessarily seal the piston assembly relative to the guide tube, but merely ensures that the radial gap existing between the cladding tube and the guide tube also remains in movement phases of the piston assembly at the other longitudinal end and stops the cladding tube against the guide tube.
• the centering component can therefore have a centering section which protrudes axially in the direction away from the cladding tube. Since no sealing effect has to be expected from the centering section, the maximum radial dimension of the centering section may preferably be less than the maximum radial dimension of the seal arrangement at the longitudinal seal end.
• the piston assembly is always to be considered in a state in which it is not surrounded by a guide tube but is exposed.
• centering section is designed to run continuously around the piston axis.
• centering would also be interrupted in the circumferential direction about the piston axis interrupted training of the centering, for example in the form of three circumferentially equidistant centering fingers, which protrude away from the cladding tube.
• the number of centering fingers may be greater than three, but preferably the number of three fingers which are spaced apart at an angular distance of 120 ° is preferred. In this case, the fingers can be formed very narrow in the circumferential direction, so that their frictional effect is low, without losing centering effect.
• the centering section In the case of the finger-like design of the centering section, its radial dimension in a state of the piston assembly removed from a guide tube can also be readily greater than the maximum radial dimension of the seal arrangement.
• the centering has a central in the radial direction, extending in the axial direction recess. It is preferred for the sealing arrangement and / or for the further sealing arrangement and / or the centering component to be as frictionless as possible. chosen material which forms at least the contact with the surrounding the piston assembly during operation guide tube in sliding contact.
• the guide tube is made of glass, it may be provided to reduce the friction that the sealing arrangement and / or the further sealing arrangement and / or the centering component at least on a radially outwardly facing surface of the sealing portion or the centering of a with Solid particles filled plastic is formed, in particular made of mica and / or graphite particles filled PTFE or polyolefin is formed.
• Solid particles filled plastic in particular made of mica and / or graphite particles filled PTFE or polyolefin is formed.
• the abovementioned low-friction materials for forming the contact surfaces are also applicable to guide tubes made of other materials, for example on metallic guide tubes.
• the sealing arrangement as a whole or the centering component as a whole is preferably formed from one of the named materials, preferably injection-molding technology.
• the cladding tube is formed from a non-magnetic and non-magnetizable material, particularly preferably made of stainless high-alloy steel, since it can be produced with high intrinsic stiffness with thin wall thickness with high dimensional and dimensional accuracy.
• the cladding tube is also made of plastic, in particular made of fiber- and / or particle-reinforced plastic, whereby similarly high strengths as in the aforementioned high-alloy steel can be achieved with less mass.
• the cladding tube is preferably designed as a solid tube, but may be designed to save mass as a skeleton tube with radial openings.
• the present invention further relates to a pipetting device having a piston assembly formed as described above.
• the pipetting device has a guide tube extending along a cylinder axis, in which the piston assembly is received in an axially movable manner with a piston axis which is coaxial with the cylinder axis.
• Radially outside the piston receiving space of the guide tube coil windings are preferably arranged, which generate by energizing a magnetic field through which the piston assembly is drivable for axial movement along the cylinder axis.
• the pipetting device has a coupling formation, to which a pipetting tip can be detachably coupled as intended.
• the coupling formation closer to the longitudinal end of the guide tube is the coupling longitudinal end.
• the guide tube communicates fluid dynamically with the coupling formation.
• the guide tube of the pipetting device is open at its longitudinal end remote from the coupling formation (maintenance longitudinal end) or closed by a cover which can be released as intended.
• the piston assembly can be easily replaced by being extended by the coils of their movement drive away from the coupling formation through the open maintenance longitudinal end of the guide tube, that it can be grasped by hand or by a tool and can be pulled out of the guide tube. If necessary, remove the lid, which has been removed as intended, from the guide tube. Then either the at least one seal assembly and / or the centering member can be replaced on the piston assembly, or the piston assembly can be replaced as a whole.
• the reconditioned or new piston assembly is inserted through the open maintenance longitudinal end of the guide tube in this and so far into the guide tube of Hand or with a tool moved in until it is sufficiently in the effective range of the coils of the electromagnetic drive.
• This can then drive the piston assembly for axial movement, preferably first in a reference position, such as a bottom dead center, from where then the position detection of the piston assembly is referenced.
• the pipetting device and its control are then set up for a continuation of the pipetting operation.
• Fig. 1 is a rough schematic longitudinal sectional view through an inventive
• Embodiment of a permanent-magnetic piston assembly of the present invention and Fig. 2a-c) an inventive embodiment of a roughly schematically illustrated pipetting with the guide tube movably received piston assembly of Fig. 1 in different relative positions relative to the guide tube and the guide tube surrounding the coil assembly as a drive device.
• FIG. 1 is an embodiment of a permanent magnet piston assembly of the present invention generally designated 10.
• the piston assembly 10 extends along a piston axis K and comprises a concentric to the piston axis K cladding tube 12, which forms a kind of outer skeleton of the piston assembly 10.
• the cladding tube 12 may be formed of a non-magnetic and non-magnetizable metal, for example of a high-alloy stainless steel.
• the cladding tube can also be made of plastic, for reasons of strength, in particular of filled, especially fiber-reinforced plastic.
• a Hüllrohrachse H thus coincides with the piston axis K.
• the cladding tube 12 are preferably a plurality of permanent magnet assemblies 14a, 14i, ... to 14m arranged along the piston axis K successively, wherein between each two immediately axially successive permanent magnet assemblies 14i, 14j a preferably ferromagnetic separator 16 is arranged.
• all separating bodies 16 have the same design and have a substantially smaller axial length than the permanent magnet arrangements 14i, 14j which adjoin them on both sides.
• the permanent magnet arrangements 14a to 14m are arranged such that poles of the same name between the two axially closest permanent magnet arrangements 14i, 14j face one another or adjoin the separating body located between these permanent magnet arrangements.
• the north pole of the permanent magnet arrangement 14 a adjoins the separating body 16.
• the north pole of the permanent magnet assembly 14b may abut the separator 16 located between the permanent magnet assemblies 14a and 14b.
• the permanent magnet arrangements 14a to 14m are arranged along the piston axis K with alternating polarization in order to generate in the area of the separating body 16 an axial magnetic field gradient which is as pronounced as possible.
• the resulting from the arrangement of the permanent magnet assemblies 14a to 14m with alternating polarization magnetic field serves both to couple the most effective coupling of the piston magnetic field to the magnetic field of the guide tube 30 (see Fig. 2a-2c) surrounding the coil assembly 32 to a positionally accurate as possible
• each permanent magnet arrangement 14a to 14m is formed by exactly one permanent magnet. However, it should not be excluded if this For manufacturing reasons, it might be helpful to form a permanent magnet arrangement with a north pole and a south pole of a plurality of permanent magnets or a combination of permanent magnets and magnetizable components.
• the permanent magnet arrangements 14a to 14m and the separating bodies 16 arranged between them can be glued by an adhesive film to the inner wall of the cladding tube 12 and thus secured in position.
• the cladding tube 12 may be coated with adhesive prior to insertion of the permanent magnet arrangements and the separating body 16 on its inner wall.
• the permanent magnet arrangements and separating bodies can be coated on their lateral surfaces with adhesive.
• the cladding tube 12 is present preferably circular cylindrical.
• the permanent magnet arrangements 14a are preferably solid-circular-cylindrical, as are the soft-magnetic, preferably ferromagnetic separation bodies 16.
• the cladding tube 12 has at one end a sealing longitudinal end 18 and has a longitudinal end 20 opposite the sealing longitudinal end 18.
• a sealing arrangement 22 is preferably provided in the form of a sealing component.
• a sealing component 22 or the centering component 24 shown in FIG. 1 can likewise be arranged.
• the sealing component 22 has a connecting portion 26, which protrudes axially into the cladding tube 12 at its sealing longitudinal end 18 and can also be glued by means of an adhesive to the inner wall of the cladding tube 12.
• the sealing member 22 has a sealing portion 28 which projects away from the cladding tube 12 in the axial direction.
• This sealing portion 28 preferably has a sleeve formation 34, which, for example, bell-shaped in the direction of the cladding tube 12 may be formed axially widening away. A section of the sleeve formation 34 projects radially beyond the cladding tube 12 in order to be able to pass undisturbed through the cladding tube 12 into contact with the guide tube 30 and thus to be able to fulfill its sealing function.
• the sealing arrangement or sealing component 22 may have a central recess 36 into which a tool or a threaded rod can be screwed in order, for example, to pull the sealing component 22 out of the cladding tube 12 or to be able to press it radially against the inner wall of the cladding tube 12 and thus to be able to anchor more strongly to the cladding tube 12.
• the centering component 24 which is shown by way of example at the other longitudinal end 20 of the cladding tube 12, also has a fixing section 40, which, analogously to the connecting section 26, is introduced axially into the cladding tube 12 from the longitudinal end 20. Also, the fixing portion 40 may be adhesively bonded by adhesive to the inner wall of the cladding tube 12.
• the centering member 24 further includes a centering portion 42 which projects axially beyond the cladding tube 12 out therefrom, wherein an effective portion 44 of the centering 42 has a radially larger dimension than the cladding tube 12 and beyond this either along the entire circumference or in Sections radially distributed around the circumference.
• the radial projection of the active portion 44 is less than the radial projection of the sleeve portion 34 of the centering member 22 in order to avoid unnecessary frictional resistance at the centering member 24.
• the centering member 24 serves together with the sealing member 22 to avoid contact of the cladding tube 12 with the operationally surrounding guide tube.
• the centering member 24 may have an accessible from its free longitudinal end forth recess 46, in which a tool for facilitated removal of the centering member 24 from the cladding tube 12 is inserted and fixed.
• the recess 46 can, contrary to the representation in FIG. 1, extend axially into the region of the cladding tube 12 and serve for pressing the centering component 24 radially against the inner wall of the cladding tube 12.
• the centering component 24 and the sealing component 22, which are preferably formed in one piece, are preferably made of plastic, specifically of a filled, ferroplastic plastic, wherein the plastic matrix is preferably polytetrafluoroethylene or a polyolefin and embedded therein solid particles of mica or of graphite are.
• FIGS. 2a to 2c the piston assembly 10 of FIG. 1 is shown in different relative positions.
• the permanent-magnetic piston assembly 10 along the coincident in operation with the piston axis K cylinder axis Z of the guide tube 30 can be moved with high precision and fast.
• the guide tube 30 has a coupling longitudinal end 48 closer to a coupling formation, not shown in FIG. 2, and a longitudinal end or maintenance longitudinal end 50 opposite thereto on the maintenance side.
• the maintenance-side longitudinal end 50 of the guide tube 30 is open in the example shown. It can also be closed by a cover 51 which is arranged detachably on the maintenance-side longitudinal end 50 and which forms an end stop of the piston assembly 10 for limiting its axial movement path in the direction of the maintenance-side longitudinal end 50.
• the piston assembly 10 can be axially moved out of the guide tube 30 at least so far that their removal longitudinal end 54 formed by the centering member 24 is no longer surrounded by the guide tube 30 and thus be grasped by hand or by a tool can. This makes it possible to completely pull the piston assembly 10 axially out of the guide tube 30 and completely remove it from the guide tube.
• a serviced or a new piston assembly 10 can then be inserted axially into the guide tube 30 with the piston-sealing longitudinal end 56 having the sealing component 22 (see Fig.
• the piston assembly 10 can be completely retracted by the magnetic field of the coil assembly 32 in the guide tube 30.
• the lid 52 may then be re-attached to the maintenance-side longitudinal end 50 of the guide tube 30, if necessary.
• the coil arrangement 32 can move the retracted piston assembly 10 into a defined reference position determined, for example, by a mechanical stop, where its sensor system is referenced to the known position. Subsequently, the pipetting device is again ready for operation with high dynamics and high accuracy.

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• Physics & Mathematics (AREA)
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• 2016
  • 2016-10-18 DE DE102016220424.6A patent/DE102016220424A1/de not_active Withdrawn
• 2017
  • 2017-10-11 CN CN201780064680.5A patent/CN109843440B/zh active Active
  • 2017-10-11 EP EP17791603.8A patent/EP3528953B1/de active Active
  • 2017-10-11 US US16/343,209 patent/US11291987B2/en active Active
  • 2017-10-11 JP JP2019541862A patent/JP2019533577A/ja active Pending
  • 2017-10-11 WO PCT/EP2017/075951 patent/WO2018073073A1/de not_active Ceased

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