WO2018026171A1 - Composition cosmétique automoussante et procédé de préparation de cette composition - Google Patents

Composition cosmétique automoussante et procédé de préparation de cette composition Download PDF

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Publication number
WO2018026171A1
WO2018026171A1 PCT/KR2017/008299 KR2017008299W WO2018026171A1 WO 2018026171 A1 WO2018026171 A1 WO 2018026171A1 KR 2017008299 W KR2017008299 W KR 2017008299W WO 2018026171 A1 WO2018026171 A1 WO 2018026171A1
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weight
cosmetic composition
self
parts
skin
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PCT/KR2017/008299
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English (en)
Korean (ko)
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김태곤
Original Assignee
주식회사 파이온텍
김태곤
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=61073494&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2018026171(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 주식회사 파이온텍, 김태곤 filed Critical 주식회사 파이온텍
Priority to CN201780062082.4A priority Critical patent/CN109843250B/zh
Publication of WO2018026171A1 publication Critical patent/WO2018026171A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/20—Halogens; Compounds thereof
    • A61K8/21—Fluorides; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241—Containing particulates characterized by their shape and/or structure
    • A61K8/0245—Specific shapes or structures not provided for by any of the groups of A61K8/0241
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/22—Gas releasing
    • A61K2800/222—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/48—Thickener, Thickening system

Definitions

  • a self-foaming cosmetic composition comprising a fluorine compound and a surfactant, a product comprising the same, and a method of preparing the composition and / or product are provided.
  • active active ingredients used in functional cosmetics adenosine, arbutin, niacinamide, alpha-visabo, vitamins, and various sunscreens are used.However, products containing these ingredients have low skin absorption and thus improve wrinkles, whitening, and ultraviolet rays. The effects of blocker ingredients on the skin are minimal. Therefore, development of a technique for promoting skin absorption of the active ingredient is required.
  • skin care products are divided into solubilization type liquid and gel phases, emulsion type lotion and cream phases, and are used in various forms depending on the dosage form and skin type.
  • the emulsion type is typical of lotion, essence, and cream formulations. It is characterized by giving skin care effect by blending.
  • the emulsion dog type has a disadvantage in that it contains a large amount of an oil phase (oil component) to inhibit bubbles of components having self-expandability.
  • a cosmetic composition and a method for preparing the same are provided, which maintain the self-expandability of the fluorine compound even though it contains an oily component (oil), and promote the percutaneous absorption by the self-expanding fluorine compound and improve skin tone. .
  • a self-foaming cosmetic composition comprising a fluorine compound and a surfactant.
  • the self-foaming cosmetic composition may further include one or more selected from the group consisting of oils, polyols, thickeners and the like.
  • the cosmetic composition may further comprise one or more additives and / or one or more active ingredients.
  • the self-foaming cosmetic composition may be a composition intended to absorb the skin / hair / scalp of the composition itself and / or the active ingredient further included, and is not a composition that does not need to be wiped, such as a cleaning (cleansing) composition. Can be.
  • the product may be a product intended to absorb skin / hair / scalp, and may not be a cleaning (cleansing) composition. .
  • Another example provides the self-foaming cosmetic composition or a method for producing a product comprising the same.
  • Another example provides the use as a self-foaming cosmetic or a product comprising the mixture of a fluorine compound and a surfactant or for the preparation of a self-foaming cosmetic composition or a product comprising the same.
  • the mixture may further include one or more selected from the group consisting of oils, polyols, thickeners, and the like.
  • the mixture may further comprise one or more additives and / or one or more active ingredients.
  • the self-foaming cosmetic composition or a product containing the same may be a composition or product intended to absorb skin / hair / scalp, the cleaning (cleansing) composition is It may not.
  • the present invention relates to a cosmetic composition containing a fluorine compound and having a self-foaming (bubble generation) formulation and a method for producing the same.
  • the self-foaming cosmetic composition may be in the form of an emulsified or solubilized form of 0 / W or 0 / W / 0 formulation, contains a fluorine compound and a surfactant (emulsifier), and optionally depending on the desired purpose or effect It may have a property of a lotion, essence, or cream further comprising one or more selected from the group consisting of oils, polyols, thickeners, humectants, skin active ingredients and the like.
  • the composition exhibits self-foaming (bubble development) when applied to the skin, thereby immediately lowering skin temperature, increasing the absorption of skin active ingredients, thereby maximizing the skin effect, improving skin tone, and / or activating the keratin turnover cycle. It is characterized by showing useful effects such as.
  • the skin care functions such as moisturizing, soothing, and / or converging using fluorine compounds are generated while bubbling (maintaining or enhancing), and having a new skin cooling effect.
  • Cosmetic compositions in the form and methods of making the same are provided.
  • the technology provided herein has a property such as liquid, gel, lotion, cream, etc.
  • the present invention relates to a composition and a method for preparing the same, and is characterized by a constant implementation rate and amount of bubbles having an excellent skin care effect.
  • a cosmetic composition comprising a fluorine compound and a surfactant
  • the first cosmetic composition is a self-foaming cosmetic composition having a self-foaming property.
  • the crab 1 cosmetic composition may further include one or more selected from the group consisting of oils, polys, thickeners, and the like (second cosmetic composition). Although the second cosmetic composition includes an oil component, the second cosmetic composition is characterized by maintaining self-foaming property.
  • the cosmetic composition (first cosmetic composition or roughly 12 cosmetic composition) is commonly used in cosmetic compositions, such as non-cleaning products, such as ion blockers, emulsion stabilizers, pH adjusting agents, skin conditioning agents, etc. It may be one containing at least one selected from the group consisting of all possible additives (third cosmetic composition).
  • the cosmetic composition (the first cosmetic composition, the crab 2 cosmetic composition, or the third cosmetic composition) has properties that are beneficial to the skin, scalp and / or hair, such as moisturizers, skin whitening agents, skin firming agents, and skin wrinkle enhancers. It may further include one or more (active ingredient) selected from the group consisting of all the active ingredients that can be imparted (fourth cosmetic composition)
  • an additive that can be conventionally contained (used) in a cosmetic composition may mean any ingredient that is allowed to be contained (used) in an external product applied to skin / scalp / hair.
  • the cosmetic compositions 1 to 4 may each be emulsified, dispersed, suspended, or dissolved in a suitable solvent (eg, purified water, rock water, sea water, deep sea water, plant extract water, etc.).
  • a suitable solvent eg, purified water, rock water, sea water, deep sea water, plant extract water, etc.
  • the 'cosmetic composition' or 'self-foaming cosmetic composition' means one or more selected from the cosmetic compositions 1 to 4 and the forms contained in the appropriate solvent.
  • the cosmetic composition may be an emulsion (eg, O / W or O / W / O) or a solubilization type of formulation, and may be a self-foaming composition capable of self foaming.
  • the cosmetic composition provided herein is interpreted to mean a self-foaming composition having self-foaming property, unless otherwise stated.
  • the bubble layer generated on the surface of the skin by the self-foaming cosmetic composition serves to improve the skin absorption of the active ingredient included in the cosmetic composition with the skin cooling effect, it can exert an effect on skin tone improvement.
  • the self-foaming cosmetic composition is absorbed into the skin by disappearing the generated bubble layer in a suitable time, it is removed from the skin (wipe with a tissue, puff, etc. It does not need to wash). Therefore, the self-foaming cosmetic composition may be a composition intended to absorb skin / hair / scalp rather than cleaning, it may be applied to the skin / hair / scalp and the like without wiping. In one example, the self-foaming cosmetic composition may not be a cleaning (cleansing) composition.
  • the self-foaming cosmetic composition is applicable to all skin, scalp, hair and the like of the body, including the face, hands and feet.
  • the fluorine compound acts as a gas carrier, delivers gas to the skin, and lowers the interfacial tension of the surfactant, thereby acting as a blowing agent to generate bubbles as the gas vaporizes.
  • the fluorine compound may exhibit a skin softening effect.
  • the stratum corneum located on the outermost side of the skin, tends to be less permeable to active ingredients (active ingredients). This is because the stratum corneum is composed of keratin fibrous keratinocytes and a bicomponent structure in which lipid components are densely sandwiched therebetween.
  • the composition having a self-foaming function by the fluorine compound is applied to the skin surface, the stratum corneum permeability and skin absorption rate of the active ingredient in the composition may be enhanced by the bubble layer formed on the skin surface and the skin softening effect of the bubble layer. .
  • the said fluorine compound can use all the kinds normally applied to a cosmetic composition,
  • Perfluorodecalin, perfluoronucleic acid and the like may include one or more selected from the group, but is not limited thereto.
  • the cosmetic composition content in the total% by weight of 100 parts by weight of the fluorine compound is 0.1 to 20 parts by weight 0/0, and 0.5 to 20 parts by weight 0/0, or 1 to 20 parts by weight 0/0, for example, 0.5 to 18 parts by weight 0/0, and 0.5 to 16 parts by weight 0/0, and 0.5 to 14 parts by weight 0/0, and 0.5 to 12 parts by weight 0/0, and 0.5 to 10 parts by weight 0 / 0,1 to 18 weight 0/0, 1 to 16 parts by weight 0/0, 1 to 14 parts by weight 0/0, 1 to 12 parts by weight 0/0, 1 to 10 parts by weight 0/0, and 1.5 to 20 parts by weight 0/0, and 1.5 to 18 weight 0/0, and 1.5 to 16 parts by weight 0/0, and 1.5 to 14 parts by weight 0/0, and 1.5 to 12 parts by weight 0/0, and 1.5 to 12 parts by weight 0/0, and 1.5 to 12 parts
  • the surfactant may have a function of generation of bubbles, reduction of surface tension, skin softness, stabilization of a formulation, and the like.
  • nonionic surfactants and / or anionic surfactants can be used.
  • Nonionic surfactants do not charge the hydrophilic group, but have a plurality of polar groups in the molecule, and thus the affinity with water is free. Therefore, since the nonionic surfactant is the kind of emulsifier with the least irritation to the skin, it is advantageous for use in basic cosmetics applied to the skin for a long time, such as emulsion, cream, essence and the like.
  • nonionic surfactants include polyoxyethylene surfactants, polyglycerol surfactants, and sugar ester surfactants. Since nonionic surfactants are electrically neutral, they are less sensitive to the presence of electrolytes and are less affected by pH. The nonionic surfactants are designed to control the solubility by designing the degree of polymerization of hydrophilic groups during synthesis.
  • anionic surfactants have anionic charges with hydrophilic groups, and the hydrophilic groups are dissociated into anions in water.
  • Anionic surfactants are used in soaps, shampoos and cleansing products because they have excellent cleaning and foaming effects.
  • Anionic surfactants are obtained by chemical synthesis from petroleum by-products and have strong skin irritation.
  • the cosmetic composition proposed in an example of the present specification is a cosmetic composition (for example, a basic cosmetic composition) that is not for cleaning, adopting a nonionic surfactant as the surfactant has more irritation to the skin than an anionic surfactant. It is advantageous in that it is small and its affinity with water is free.
  • the surfactant contained in the cosmetic composition is non-ionic It may be a surfactant.
  • the nonionic surfactant may be a synthetic surfactant, naturally occurring surfactant, or a combination thereof.
  • the nonionic surfactant may be at least one selected from the group consisting of polyoxyethylene surfactants, polyglycerol surfactants, sugar ester surfactants, and the like.
  • the nonionic surfactant is selected from the group consisting of polyglyceryl-3methylglucose distearate, polyglyceryl-distearate (eg, polyglyceryl-10 distearate, etc.), hydrogenetidrecithin, cetearyl Olibate, sorbitan oleate, PEG (poly (ethylene glycol))-stearates (eg PEG-100 stearate, PEG-40 stearate, etc.), glyceryl stearate, glyceryl stearate, decylglucoside , coco-glucoside, lauryl glucoside, caprylyl / caprylyl glucoside, arachidyl glucoside, ci 2 - 2 o (straight chain a is a branched) alkyl glucosides, cetearyl glucosides, Sete Ares acids (e.g., sejje Ares- 20
  • the content of the surfactant (eg, nonionic surfactant) in the total weight of the cosmetic composition is 100% by weight.
  • an anionic surfactant in addition to the nonionic surfactant, an anionic surfactant may be further included.
  • the anionic surfactants include sodium lauryl sulfate, lauryl ammonium sulfate, lauryl magnesium sulfate, lauryl triethanolamine, polyoxyethylene lauryl sodium sulfate, polyoxyethylene lauryl sulfate, sodium coco ampoacetate, ammonium laures sulfate, Ammonium Lauryl Sulfate, Cocamide M, Disodium Laureth Sulfosuccinate, TEI-Cocoyl Glutamate, Sodium Cocoyl Apple Amino Acid, Cocamide Die, Sodium Laures Sulfate, Sodium Lauryl Sulfate, Potassium Cocoil It may be at least one selected from the group consisting of glycinate, sodium stearoyl glutamate, potassium cetyl phosphate and the like.
  • a cosmetic composition total weight based on 100% by weight of 2 0/0 or less Or less, e.g., 1.8 wt. 0/0 or less, or less than, 1.6 wt. 0/0 or less, or less than, L4 weight 0/0 or less, or less than, 1.2 wt. 0/0 or less, or less than, 1.1 wt 0 ⁇ or less, or less than, 1, weight 0 /.
  • the content of the anionic surfactant may include 0 wt%
  • the lower limit may be any number selected from the range up to the upper limit described above, including 0, for example : 0 can be a weight of 0/0, 0.00001 wt 0/0, 0.0001 parts by weight 0/0 0.001 0/0 0 0.01 / 0 0.05 0/0 or 0.1% by weight.
  • the self-foaming type cosmetic composition comprising sound does not include a surface active agent, following a small amount, that is, may be one containing an anionic surfactant to less than 2 wt%, or 1.1 wt. 0/0.
  • the content ratio (fluorine compound weight: nonionic surfactant weight) between the fluorine compound and the surfactant (nonionic surfactant) in the self-foaming cosmetic composition is 1-20: 0.1-10, 1-20: 0.5 To 5, or 1 to 20: 0.5 to 3, for example, 1: 0.2 to ' 1.2 or 1: 0.2 to 1.
  • the self-foaming cosmetic composition has a content ratio (nonionic surfactant weight: anionic surfactant weight) between the nonionic surfactant and the anionic surfactant between the nonionic surfactant and the anionic surfactant is 1: 0.
  • the oil that can be contained in the self-foaming cosmetic composition is at least one selected from the group consisting of all oil components that can be commonly contained (used) in cosmetics such as silicone oils, non-silicone oils, triglycerides, waxes, and the like. Can be.
  • the content of oil in the total 100% by weight of the cosmetic composition is 0.01 to 10 parts by weight 0/0, from 0.01 to 8 parts by weight 0/0, and 0.01 to 5 parts by weight 0/0, 0.01 to 4 parts by weight 0/0, 0.01 to 3 increase% , 0.1 to 10 parts by weight 0/0, and 0.1 to 8 parts by weight 0/0, and 0.1 to 5 parts by weight 0/0, and 0.1 to 4 parts by weight 0 /., 0.1 to 3% by weight, 0.5 to 10% by weight, 0.5 to 8 parts by weight 0 / 0, and 0.5 to 5 parts by weight 0/0, () 0.5 to 4 parts by weight 0/0, and 0.5 to 3 parts by weight 0/0, 1 to 10 parts by weight 0/0, 1 to 8 parts by weight 0 / 0,1 to 5 parts by weight 0/0, 1 to 4 it can be on the order of weight 0/0, or 1 to 3 parts by weight 0/0.
  • the silicone oil may have a function such as providing a soft feeling, improving stickiness, surface lubrication, and the like, and may be selected from all kinds commonly used in cosmetics.
  • the silicone oil may be cyclopentasiloxane, dimethicone, dimethicone, cyclomethicone, trisiloxane, amodimethicone, phenyltrimethicone, disiloxane, cyclonuclear siloxane,
  • PEG-dimethicones e.g. PEG-12 dimethicone, PEG-10 dimethicone, PEG-7 dimethicone, etc.
  • polysilicones e.g., polysilicon-11, etc.
  • simethicone, diphenyldimethicone, PEG -9 may be one or more selected from the group consisting of polydimethylsiloxyethyldimethicone and the like, but is not limited thereto.
  • the non-silicone oil means an oil component that can be used in cosmetics other than silicone oil, and may have a function such as moisturizing effect, oil control, and / or improvement in feeling.
  • the non-silicone oil may be selected from all kinds of oil components commonly used in cosmetics in addition to silicone oils.
  • the non-silicone oil may be caprylic / capric triglyceride,
  • the cosmetic composition content in the total 100% by weight of the non-silicone oil is 0.01 to 10 parts by weight 0/0, 0.01 to 8 wt.
  • a cosmetic composition is 0.01 to 10 parts by weight 0/0, 0.01 to 8 parts by weight 0/0, and 0.01 to 5 parts by weight 0/0, 0.01 to 4 parts by weight 0/0, 0.01 to 3 parts by weight 0/0, and 0.1 to 10 parts by weight 0/0, and 0.1 to 8 parts by weight 0/0, and 0.1 to 5 weight 0/0, and 0.1 to 4 parts by weight 0/0, and 0.1 to 3 parts by weight 0/0, and 0.5 to 10 parts by weight 0/0, and 0.5 to 8 parts by weight 0/0, and 0.5 to 5 parts by weight 0/0, and 0.5 to 4 parts by weight 0 / 0, can be on the order of 0.5 to 3 parts by weight 0/0, 1
  • the polyol may be moisturizing and have a wettability and a solubility enhancing function, and may be selected from all kinds commonly used in cosmetics.
  • the polyol may be butylene glycol, glycerin, glycerin (e.g., glycerin -26, etc.), methylpropanediol, PEG (poly (ethylene glycol)) / PPG (poly (propylene glycol)) coplicants (eg, PEG / PPG-l 7/6 copolymer and the like), methylglucamine process flow (e.g., methylglucamine access -20, and so on), dipropylene glycol, propylene glycol, propane dieul caprylate rilgeul glycol, pentyl rengeul It may be at least one selected from the group consisting of lycols, but is not limited thereto.
  • the cosmetic composition content in the total 100% by weight of the polyol is 0.1 to 20 parts by weight 0/0, and 0.1 to 18 parts by weight 0/0, and 0.1 to 15 weight 0/0, and 0.1 to 13 parts by weight 0/0, 0.1 to 10 parts by weight 0/0, and 0.3 to 20 parts by weight 0/0, and 0.3 to 18 parts by weight 0/0, and 0.3 to 15 parts by weight 0/0, and 0.3 to 13 parts by weight 0/0, and 0.3 to 10 parts by weight 0 / 0,0.
  • the thickener may be one having a function of improving the viscosity of the formulation and helping to stabilize the emulsion, and may be selected from all kinds commonly used in cosmetics.
  • the thickener is carbomer, ammonium acryloyl dimethyl taurate / V-picopolymer, xanthan gum, sodium polyacrylate, hydroxyethyl cellulose, acrylate / C10-30 alkyl acrylate crosspolymer, sodium poly Acrylate, sodium acrylate / sodium acryloyl dimethyl taurate copolymer,
  • Magnesium aluminum silicate, sodium carbomer may be one or more selected from high molecular compounds, but is not limited thereto.
  • a cosmetic composition content in the total of 100 weight percent of the thickener is 0.01 to 2 parts by weight 0/0, 0.01 to 1.5% by weight 0.01 to 1 parts by weight 0/0, 0.01 to 0.5 0/0, 0.05 to 2% by weight, 0.05 to 1.5 parts by weight 0/0, 0.05 to 1 parts by weight 0/0, 0.05 to lead 5 increased 0/0, 0.1 2 can be on the order of weight 0/0, and 0.1 to 1.5 parts by weight 0/0, and 0.1 to 1 weight 0/0, or 0.1 to 0.5 0/0.
  • the thickener may be applied by selecting an appropriate kind and / or content in accordance with the viscosity of the desired formulation.
  • the self-foaming cosmetic composition may further comprise one or more selected from all the additives available for the preparation and / or formulation of the cosmetic composition in a conventional content range.
  • the additive is an ion blocker, emulsion stabilizer, pH adjuster, skin conditioner, flavoring agent, preservative, fungicide, oxidation stabilizer, antioxidant, free radical destroyer, opaque agent, which are commonly used in cosmetic preparation , Stabilizers, emollients, vitamins, toxins, preservatives, anti-inflammatory agents, basicizing or acidifying agents, colorants, and the like may include one or more selected from the group, but is not limited thereto.
  • the solvent may be at least one selected from all the solvents used for preparing the cosmetic composition, for example, may be at least one selected from the group consisting of purified water, rock water, hot spring water, glacial water, seawater, deep ocean water, plant extract water, and the like.
  • the present invention is not limited thereto.
  • the bubble generation time (the time from the beginning of the bubble until the maximum bubble generation) is about 5 to about 40 seconds, for example, 7 to 37 seconds, Or 10 seconds to 33 seconds
  • the bubble extinction time (the time from when the generated bubbles begin to disappear to a minimum level) is from about 10 seconds to about 120 seconds, such as from 10 seconds to 100 seconds, from 10 seconds to 90 seconds, 20 seconds to 100 seconds, 20 seconds to 90 seconds, 30 seconds to 100 seconds, 30 seconds to 90 seconds, 40 seconds to 100 seconds, 40 seconds to 90 seconds, 50 seconds to 100 seconds, or 50 seconds to 90 It may be seconds.
  • the additive self-foaming cosmetic composition may have a skin surface silver of at least about 0.5 ° C., at least about O. C, or at least about 1 ° C. (eg, 0.5 to 2 ° C, 0.7 to 2 ° C, or 1 when applied to the skin). To 2 ° C) can have a lowering effect.
  • the self-foaming cosmetic composition may further include an active ingredient exerting a beneficial effect on skin (skin) care and / or hair / scalp care in addition to the aforementioned ingredients.
  • the beneficial effects include skin whitening, skin elasticity improvement, skin wrinkle improvement, skin aging, skin hydration, skin hydration, skin nutrition, pore reduction, skin texture improvement, exfoliation, skin volume improvement, scalp protection, scalp Or it may mean skin sebum prevention, hair loss prevention, hair hydration, hair nutrition, hair volume improvement, etc., but is not limited thereto, and may be any desired effect on the skin / hair / scalp of the application target.
  • the active ingredient may be a variety of plant extracts (e.g., hair extract, green tea extract, grape extract, lotus extract, tomato extract, gold coin extract, camellia extract, seaweed extract, etc.), plant callus culture or culture extract, yeast extract, cells Containing or cell-free yeast cultures or culture extracts, vitamins, various peptides, lipids, or fatty acids (e.g. lipids, fatty acids, peptides, etc. derived from various shellfish) hyaluronic acid, glycosides (e.g. arbutin, etc.) It may be one or more selected from the group consisting of a compound for skin, but is not limited thereto, and may be selected and used according to the desired effect.
  • the active ingredient is hydrogenated polyisobutene
  • hydrophilid polyisobutene may be a combination of hair extract, but is not limited thereto.
  • the cosmetic composition provided herein is, when measuring the transdermal permeability using arbutin the surface component through the HPLC, transdermal transmittance is 03% or more, coming from 5 parts by weight 0/0 or more, 0.7 wt.% Or more, or 0.9 wt. to 0/0 or more features.
  • a product skin, hair, and / or scalp care products; such as cosmetics
  • the product may be any type of product (eg, lotion, cream, essence, etc.) for applying to skin, scalp, hair, etc. of the face, hands, feet, the whole body, and the like, and may not be a cleansing product.
  • Another example provides a self-foaming cosmetic composition comprising the step of mixing a fluorine compound and a surfactant or a method for producing a product comprising the same.
  • the manufacturing method may include a step of adding and mixing at least one selected from the group consisting of oils, polyols, thickeners, and the like with the fluorine compound and the surfactant.
  • the production method is one or more selected from the group consisting of a mixture of a fluorine compound and a surfactant (first mixture: crab 1 cosmetic composition) or oil, poly, thickener and the like in the first mixture To the added mixture (second mixture: second cosmetic composition), it may include the step of adding by adding one or more additives and / or one or more active ingredients to mix. '
  • the mixing step includes the steps of: mixing an aqueous phase component, mixing an oil phase component, mixing a mixture of the aqueous phase component and an oil phase component, and a mixture of the aqueous phase component and an oil phase Mixing a fluorine compound with a mixture of the components of the mixture, and optionally, Dispersing the water and oil mixtures may be further included in the solvent.
  • the mixing step of the aqueous phase component and the mixing step of the oil phase component may be performed sequentially or simultaneously. When the steps are performed sequentially, the order may be performed in the order described above or vice versa.
  • the oil phase component may include an emulsifier, an oil component, an oily solvent, and the like, and the water phase component may mean a cosmetic component except the oil phase component, such as a polyol, a thickener, an active ingredient, an aqueous solvent, and the like.
  • the mixing step may be carried out until homogeneous mixing is achieved by a conventional mixing method such as stirring, the mixing conditions are carried out under conventional cosmetic mixing conditions (eg, 30 to 80 ° C and atmospheric pressure) Can be.
  • a conventional mixing method such as stirring
  • the mixing conditions are carried out under conventional cosmetic mixing conditions (eg, 30 to 80 ° C and atmospheric pressure) Can be.
  • the manufacturing method or the mixing steps performed during the manufacturing method may include the following steps:
  • step c) slowly disperse the oil phase dissolved in step b) into the aqueous phase dissolved in step a) and homogeneously disperse at 1,500 to 3,500 rpm for 3 to 10 minutes at 65 to 85 ° C, 35 to 30 ° C. Step to sense; And
  • step d) adding a fluorine compound to the reaction mixture prepared in step c) and stirring uniformly.
  • a skin cooling composition comprising the cosmetic composition (first cosmetic composition, second cosmetic composition, crab 3 cosmetic composition, or fourth cosmetic composition).
  • Another example is for the preparation of skin cooling (skin temperature drop) or skin cooling composition (composition for skin temperature drop) of the cosmetic composition (first cosmetic composition, crab 2 cosmetic composition, third cosmetic composition, or fourth cosmetic composition).
  • the cosmetic composition first cosmetic composition, crab 2 cosmetic composition, crab 3
  • a skin cooling method skin temperature drop method comprising applying (eg, applying) a cosmetic composition, or crab 4 cosmetic composition) to the skin.
  • the method may further comprise absorbing the applied cosmetic composition to the skin after the applying step.
  • the method may be characterized in that it does not include the step of removing the applied cosmetic composition from the skin (eg, wiping off the skin).
  • the cosmetic composition is as described above.
  • compositions for enhancing transdermal penetration or skin absorption of an active ingredient including the cosmetic composition (first cosmetic composition, second cosmetic composition, third cosmetic composition, or crab cosmetic composition). It provides a "composition.
  • Another example is to enhance transdermal penetration or skin absorption of an active ingredient (eg, active ingredient) of the cosmetic composition (first cosmetic composition, second cosmetic composition, crab 3 cosmetic composition, or crab 4 cosmetic composition), or
  • the present invention provides a use for the preparation of a composition for enhancing transdermal penetration or a composition for enhancing skin absorption.
  • Another example is a method for enhancing the percutaneous permeation of the active ingredient or applying the cosmetic composition (first cosmetic composition, crab 2 cosmetic composition, crab 3 cosmetic composition, or gel cosmetic composition) to the skin (eg, applying)
  • the method may further comprise absorbing the applied cosmetic composition into the skin after the applying step.
  • the method may be characterized in that it does not include the step of removing the applied cosmetic composition from the skin (eg, wiping off the skin.).
  • the cosmetic composition (first cosmetic composition, second cosmetic composition, third cosmetic composition, or crab cosmetic composition) is as described above.
  • the cosmetic composition of the present invention lowers the temperature of the skin by generating a bubble using a fluorine compound which is a gas-transfer substance and has a high vaporization, and improves skin tone by promoting transdermal absorption of the active ingredient and promoting blood circulation through the generated bubbles.
  • a fluorine compound which is a gas-transfer substance and has a high vaporization
  • improves skin tone by promoting transdermal absorption of the active ingredient and promoting blood circulation through the generated bubbles.
  • the cosmetic composition of the present invention can increase the moisturizing effect by blending a relatively large amount of oil and minimize the skin irritation by using a naturally-derived surfactant of low irritation and the rate and amount of bubble generation can be kept constant.
  • 1 is a photograph showing the skin temperature change during application of the self-foaming composition according to an embodiment of the skin.
  • Figure 2 is a photograph showing the bubble generation time and the bubble disappear time when applying the self-foaming composition according to an embodiment of the skin.
  • compositions (Examples 1 to 5) and the compositions of Comparative Example 1 were prepared according to the compositions shown in Table 1 below.
  • Emulsified cetearyl isoethyl
  • Raw materials 1 to 3 were added to the stirring tank and heated to 75 ° C., homogenized and homogenized to prepare an aqueous stirring tank.
  • Raw materials 5, 6, and 8 were added to another stirring vessel, heated to 75 ° C., and completely dissolved to prepare an oil phase stirring vessel.
  • the raw material 4 was slowly added while homomixing to the prepared water-stirring tank, and uniformly dispersed.
  • the oily raw material mixture in the oil phase agitator was added to the water phase agitator at 75 T, and uniformly emulsified for 5 minutes. After the obtained emulsion was immersed at 65 ° C., a solution in which the raw material 7 was dissolved in purified water was added and uniformly dispersed for 4 minutes. After cooling the resultant obtained to 30 ° C., and then put the raw material 9 and stirred uniformly for 3 minutes, A milky lotion (o / w) composition was obtained.
  • Test Example 1 Feeling Test
  • Example 5 the composition prepared in Example 5 (hereinafter, 'self-foaming composition of Example 5') was selected and compared with Comparative Example 1. This study was conducted in 10 women aged 30 to 40 years.
  • the self-foaming composition of Example 5 was taken in an amount of two pumping and applied to the entire face according to the skin texture for absorption.
  • seven items of absorbency, soothing / converging effect, stickiness, moistness, spreadability, skin irritation degree, and overall satisfaction were evaluated. Each item was evaluated with a maximum of 5 points and a lowest 0 point (Items except skin irritation degree: higher scores were more satisfactory; skin irritation degree: lower scores were lower skin irritation).
  • the skin temperature change upon application of the self-foaming composition was measured by the following method for one day using a skin infrared thermometer.
  • the subject washes with the same face wash ( ⁇ Piontech), and makes it stable for 30 minutes in the anti-humidity chamber (temperature: 22 ⁇ 1 ° C, humidity: 40 ⁇ 5%), and then the self-foaming composition of Example 5 An appropriate amount of was applied to the left facial area of the subject.
  • Skin temperature was measured before and immediately after use of the self-foaming composition of Example 5. Specifically, the skin temperature of the left face region was measured at a distance of 2 to 3 cm using an infrared thermometer in a bare face state. After 1 minute from the measurement of the skin temperature of the bare face, the self-foaming composition of Example 5 was applied thinly and evenly to the subject's left face area in an lg dose, and after 30 seconds of bubble generation, the bubble was extinguished and then absorbed, for 10 seconds. After using the infrared thermometer was measured the temperature of the application site of the left face at a distance of 2-3cm.
  • the obtained result is shown in FIG.
  • the average facial skin temperature is 36.2 ° C
  • the average skin temperature when using Comparative Example 1 does not have self-foaming is 36.1 ° C
  • the self-foaming composition of Example 5 The average skin temperature at the time is shown to be 35 ° C, it can be seen that the immediate skin temperature lowering effect (skin cooling effect) can be obtained by the bubble generating action of the self-foaming composition.
  • Test Example 3 Measurement of Bubble Creation and Dissipation Time
  • the study was conducted on three women aged 30 years or older who were voluntarily recruited. After washing the subject with the same face wash ( ⁇ Piontech) and keeping it in a constant temperature and humidity room (temperature: 22 ⁇ 1 ° C, humidity: 40 ⁇ 5%) for 30 minutes, the self-foaming composition of Example 5 Appropriate amount was applied to the left facial area of the subject.
  • the self-foaming composition of Example 5 to calculate the time from the start of the bubble generation until the maximum bubble generation (bubble creation time) and when the generated bubble begins to disappear to the minimum level The time until (bubble decay time) was measured, respectively, and it is shown in FIG.
  • the bubble generation time is 22 seconds on average and the bubble extinction time is 78.6 seconds on average.
  • the bubble generation time and bubble disappearance time when applying the self-foaming composition may vary depending on the skin condition (degree of moisture, skin texture, skin aging, etc.) of the subject, but the above results indicate that the self-foaming composition exhibits an effective effect. It is shown that it maintains the bubble generation for a time without discomfort to use, while dividing to obtain the skin absorption and / or skin cooling effect of the ingredient. Examples 6-7 and Comparative Example 2: Preparation of Self-foaming Composition
  • Example 7 A self-foaming composition (Examples 6 to 7) was prepared according to the composition shown in Table 2 with reference to the method of Examples 1 to 5 above. However, the indicator material was added to the final process. For reference, Example 7 is the same as the composition of Example 5 except for including the indicator (albumin).
  • Emulsifier (surfactant)
  • In vitro skin absorption test method is to confirm that the test substance passes through the skin.
  • the test substance is applied to the skin surface and black or black is applied to measure the amount transferred to the solution reservoir inside the skin after a certain time.
  • Skin of artificial cells or artificial skin can be used.
  • the test substance can be repeatedly measured and the exposure condition can be studied without using an experimental animal.
  • In vitro necropsy absorption test can compare the skin absorption and permeation according to the composition of the material, It can be used as a useful model for risk assessment by skin absorption in human body.
  • the skin permeation device World Cprporation, Model GLMS-26 used in the transdermal absorption test is composed of a donor chamber and a receptor chamber, and the skin is fixed therebetween. Each cell used for the same test has the same surface area in the range of 0.3-5 cm 2 .
  • the prepared skin is fixed to the skin penetrating device with the stratum comeum positioned upward.
  • the skin penetrating device should be in close contact with the skin, should be able to homogeneously mix the aqueous solution at the bottom of the skin, the collection of the aqueous solution should be easy, and the temperature of the device and the contents should be easy.
  • the aqueous solution used for the test should be compatible with the skin tissue and should be selected taking account of the solubility of the test substance.
  • the aqueous solution uses physiological saline at pH 7.4.
  • the content of arbutin was measured via HPLC to test transdermal permeability. More specifically, the skin was fixed between the donor compartment and the receiving compartment of the skin permeation apparatus and filled with the receiving compartment without air using physiological saline. Each test material was mixed with a solvent and loaded into a donor cell, and after 24 hours, the liquid in the receiving cell was collected, and the components were analyzed by HPLC to confirm the skin permeability of the test substance. The transmittance of arbutin was calculated as the percentage of the arbutin mass of the receptacle to the arbutin mass of the donor compartment.
  • Example 7 40 healthy adult women with pigmentation were randomly divided into two groups (A and B) of 20 people each, and then the composition of Example 7 was compared to the group A, and the comparative example 2 to the group B.
  • the composition of was applied twice a day for 8 weeks.
  • the coating amount per time was 0.4-0.8 g.
  • the application amount can vary according to the individual's taste, the application amount of each composition is made to be the same.
  • the change of skin color is measured by using a spectrophotometer (Minolta CM600-d), and the brightness change (AL) of the color is measured, and the objective visual observation by a plurality of skilled persons and subjective visual observation by the subject are performed to whiten the effect.
  • the results are shown in Table 6 below.
  • the degree of whitening efficacy was evaluated according to the following whitening efficacy evaluation criteria.
  • Example 5 In order to find out the skin tone improvement effect of the self-foaming cosmetic composition of Example 5, a test was performed for 4 weeks using a spectrophotometer and an entire eye photographing system. The study was conducted on 25 women over the age of 30 voluntarily recruited. Subjects were applied to the right facial area by spreading 0.4-0.8 g of the same amount of the composition of Example 5 evenly every morning and evening after washing for 4 weeks during the test period.
  • the brightness change (AL) of color was measured using a spectrophotometer after one use, two weeks, and three weeks, and the results are shown in Table 7 below. Subject's subjective skin condition was examined and the results are shown in Table 8 below.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
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  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Physics & Mathematics (AREA)
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  • Cosmetics (AREA)

Abstract

L'invention concerne : une composition cosmétique automoussante contenant un composé fluoré et un tensioactif ; un produit comprenant cette composition ; et un procédé de préparation de ladite composition et/ou dudit produit.
PCT/KR2017/008299 2016-08-05 2017-08-01 Composition cosmétique automoussante et procédé de préparation de cette composition WO2018026171A1 (fr)

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KR102096010B1 (ko) * 2018-09-10 2020-04-02 주식회사 코리아나화장품 모발의 건조 시간 감소 및 유연감 개선 효과를 갖는 모발 화장료 조성물
KR20200105033A (ko) 2019-02-28 2020-09-07 주식회사 맥클린코스메틱 펩타이드 볼륨 에센스
KR102234579B1 (ko) * 2020-12-07 2021-03-31 리봄화장품 주식회사 버블 필오프 팩 화장료 조성물 및 그 제조방법
KR20220135537A (ko) 2021-03-30 2022-10-07 주식회사 코스메카코리아 자가 발포 기능을 가지는 정제 형태의 세정용 화장료 조성물
KR102561767B1 (ko) * 2022-12-27 2023-08-02 (주)비에프글로벌 다래나무 수액을 포함하는 화장료 조성물 및 이의 제조방법
CN116769266B (zh) * 2023-07-13 2024-01-23 上海芯密科技有限公司 一种半导体密封圈橡胶材料及其制备方法和应用

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KR101962952B1 (ko) 2019-03-27
KR101962952B9 (ko) 2023-12-15
KR20190122612A (ko) 2019-10-30
KR102216005B1 (ko) 2021-02-16
KR20190034510A (ko) 2019-04-02
CN109843250A (zh) 2019-06-04

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