WO2017219581A1

WO2017219581A1 - Long-acting bacteriostatic hand lotion

Info

Publication number: WO2017219581A1
Application number: PCT/CN2016/104829
Authority: WO
Inventors: 吴克
Original assignee: 江苏奇力康皮肤药业有限公司
Priority date: 2016-06-22
Filing date: 2016-11-07
Publication date: 2017-12-28
Also published as: CN105997665A

Abstract

Provided are a bacteriostatic hand lotion and a preparation method therefor. The hand lotion contains 15-18 parts of Coptis chinensis, 20-23 parts of a peppermint oil, 2-4 parts of Scutellaria baicalensis, 2-4 parts of Folium isatidis, 5-8 parts of an Artemisia argyi essential oil, 2-5 parts of Rhizoma anemarrhenae, 10-13 parts of a dandelion essential oil, 2-4.5 parts of a VE derivative, 6-10 parts of an emulsifier, 0.2-0.5 parts of a surfactant, and 3.8-6 parts of a consistency regulator, and the balance is deionized water.

Description

Long-acting antibacterial hand lotion

Technical field

The present invention relates to a functional emulsion. More specifically, the present invention relates to a long-acting bacteriostatic hand lotion.

Background technique

Hands are an indispensable organ, and most of the work in life is done by both hands, such as washing dishes, mopping the floor, doing housework, or operating tools and typing on the keyboard. With people's pursuit of beauty, the hand is given a new meaning, the hand is the second face of a woman, and women with a beautiful pair of hands tend to give a good impression. One hand can see the traces of your years, the opponent Maintenance is getting more and more attention. Our hands do a lot of work every day, and they come into contact with a lot of things, and it is inevitable that they will be contaminated with bacteria. Therefore, while moisturizing and moisturizing, they also pay attention to sterilization and bacteriostasis. However, the existing hand cream on the market is difficult to achieve long-lasting bacteriostasis, and more chemical ingredients are used, which are irritating to the skin.

Summary of the invention

It is an object of the present invention to address at least the above problems and to provide at least the advantages that will be described later.

Still another object of the present invention is to provide a long-acting bacteriostatic hand lotion which adopts a unique formulation and a preparation method to improve the activity and durability of the functional ingredient and achieve a long-lasting bacteriostatic action.

In order to achieve these and other advantages of the present invention, there is provided a long-acting bacteriostatic hand lotion comprising the following ingredients (by mass fraction):

A long-acting bacteriostatic hand lotion containing the following ingredients (by mass fraction):

Coptis, 15 to 18 servings;

Peppermint oil, 20 to 23 parts;

Astragalus, 2 to 4 servings;

Daqingye, 2 to 4 servings;

Ai Ye essential oil, 5-8 parts;

Zhimu, 2 to 5 servings;

Dandelion essential oil, 10 to 13 servings;

VE derivative, 2 to 4.5 parts;

Emulsifier, 6-10 parts;

Surfactant, 0.2 to 0.5 parts;

Consistency adjuster, 3.8-6 parts;

The balance is deionized water;

Wherein, the coptis is dissolved in the peppermint oil to form a first mixture; the scutellaria and the scutellariae are dissolved in the essential oil of the eucalyptus oil to form a second mixture; the mother is dissolved in the dandelion essential oil to form a third mixture; the first mixture is After mixing the liquid, the second mixed liquid and the third mixed liquid, a surfactant, a VE derivative, an emulsifier and a consistency adjuster are sequentially added thereto to be remixed to obtain the long-acting bacteriostatic protection Hand lotion.

Preferably, the long-acting bacteriostatic hand lotion comprises the following ingredients (by mass fraction):

Huanglian, 15 copies;

Peppermint oil, 20 parts;

Astragalus, 2 servings;

Daqingye, 2 servings;

Ai Ye essential oil, 5 parts;

Zhimu, 2 copies;

Dandelion essential oil, 10 parts;

VE derivative, 2 parts;

Emulsifier, 6 parts;

Surfactant, 0.2 parts;

Consistency adjuster, 3.8 parts;

The balance is deionized water.

Huanglian, 18 copies;

Peppermint oil, 23 parts;

Huang Wei, 4 servings;

Daqingye, 4 servings;

Ai Ye essential oil, 8 parts;

Zhimu, 5 copies;

Dandelion essential oil, 13 servings;

VE derivative, 4.5 parts;

Emulsifier, 10 parts;

Surfactant, 0.5 parts;

Consistency adjuster, 6 parts;

The balance is deionized water.

Huanglian, 16 copies;

Peppermint oil, 22 parts;

Huang Wei, 3 servings;

Daqingye, 3 servings;

Ai Ye essential oil, 6 parts;

Zhimu, 3 copies;

Dandelion essential oil, 11 parts;

VE derivative, 3 parts;

Emulsifier, 8 parts;

Surfactant, 0.3 parts;

Consistency adjuster, 5 parts;

The balance is deionized water.

Preferably, the long-acting bacteriostatic hand lotion, wherein the VE derivative is VE acetate.

Preferably, the long-acting bacteriostatic hand lotion, wherein the first mixed liquid is specifically prepared by taking a quantitative berberine, grinding it into a powder, and using distilled water to distill the mint to form steam, 8 The high-temperature steam was continuously introduced into the container containing the coptis powder within ～10 days, and the treated berberine was mixed with peppermint oil to form a first mixed liquid.

Preferably, the long-acting bacteriostatic hand lotion, wherein the second mixed liquid is prepared by separately taking a certain amount of scutellaria and dahlia, and grinding the powder into a powder and mixing. After fumigation with Ai Ye essential oil for 2 to 5 days, it is immersed in the essential oil of Ai Ye, soaked for 2 to 5 days, and shaken 3 to 6 times a day for 5 to 10 minutes each time to prepare a second mixture.

Preferably, the long-acting bacteriostatic hand lotion, wherein the third mixed liquid is specifically prepared by taking a certain amount of Zhimu, grinding it into a powder, adding dandelion essential oil, Freeze at -5 °C for 18 minutes, then shake at 80 °C for 1 hour, freeze at -5 °C for 15 minutes, shake at 75 °C for 50 minutes, and freeze at -5 °C for 12 minutes. Oscillation at 70 ° C for 40 minutes, freezing at -5 ° C for 9 minutes, then shaking at 65 ° C for 30 minutes, freezing at -5 ° C for 6 minutes, and then shaking at 60 ° C for 20 minutes, The mixture was frozen at -5 ° C for 3 minutes and then shaken at 55 ° C for 10 minutes to obtain the third mixed solution.

Preferably, the long-acting bacteriostatic hand lotion, wherein the prepared first mixed liquid and the third mixed liquid are remixed, shaken for 30 minutes to 1 hour, and then added to the second The mixed solution is heated to 100-120 ° C under a pressure of 0.5 to 1.33 kPa for 3 to 10 minutes, and then cooled to 60 ～. The mixture was filtered to remove slag at 70 °C.

Preferably, the long-acting bacteriostatic hand lotion, wherein the surface mixture is sequentially added to the mixed liquid of the first mixed liquid, the second mixed liquid and the third mixed liquid The agent, the VE derivative, the emulsifier and the consistency adjuster are remixed, and then subjected to autoclaving to obtain a long-acting antibacterial hand lotion.

The invention includes at least the following beneficial effects:

The long-acting antibacterial hand lotion disclosed in the present invention adopts pure natural botanical ingredients, so that the prepared hand lotion is beneficial to the absorption of the skin of the hand, and can also have a long-lasting antibacterial effect and has no toxic effect on the skin; Using a unique formula and preparation method to improve the activity and durability of functional ingredients, to achieve long-lasting antibacterial effect.

Other advantages, objects, and features of the invention will be set forth in part in the description in the description which

detailed description

The present invention will be further described in detail below with reference to the embodiments, so that those skilled in the art can refer to the description.

It is to be understood that the terms "having", "comprising" and "comprising" are used in the <RTIgt;

Coptis, 15 to 18 servings;

Peppermint oil, 20 to 23 parts;

Astragalus, 2 to 4 servings;

Daqingye, 2 to 4 servings;

Ai Ye essential oil, 5-8 parts;

Zhimu, 2 to 5 servings;

Dandelion essential oil, 10 to 13 servings;

VE derivative, 2 to 4.5 parts;

Emulsifier, 6-10 parts;

Surfactant, 0.2 to 0.5 parts;

Consistency adjuster, 3.8-6 parts;

The balance is deionized water;

Wherein, the coptis is dissolved in the peppermint oil to form a first mixture; the scutellaria and the scutellariae are dissolved in the essential oil of the eucalyptus oil to form a second mixture; the mother is dissolved in the dandelion essential oil to form a third mixture; the first mixture is After the liquid, the second mixed liquid and the third mixed liquid are mixed, the surface is sequentially added thereto The active agent, the VE derivative, the emulsifier and the consistency adjuster are further mixed to obtain the long-acting bacteriostatic hand lotion.

The first mixed liquid is specifically prepared by taking a quantitative berberine, grinding it into a powder, distilling the mint into distilled steam by using distilled water, and continuously transferring the high-temperature steam into the container containing the coptis powder within 8 to 10 days. The treated berberine is mixed with peppermint oil to form a first mixture.

The specific preparation method of the second mixed liquid is: taking a certain amount of Astragalus and Daqing leaves respectively, grinding them into powder, mixing them, and fumigation with Ai leaves essential oil for 2 to 5 days, and then immersing them in Ai Ye In the essential oil, soak for 2 to 5 days, shake 3 to 6 times a day for 5 to 10 minutes each time to prepare a second mixture.

The third mixed liquid is specifically prepared by taking a certain amount of Zhimu, grinding it into a powder, adding it to dandelion essential oil, freezing at -5 ° C for 18 minutes, and then shaking at 80 ° C for 1 hour. , frozen at -5 ° C for 15 minutes, then shaken at 75 ° C for 50 minutes, frozen at -5 ° C for 12 minutes, then shaken at 70 ° C for 40 minutes, and frozen at -5 ° C for 9 minutes Then, shake at 65 ° C for 30 minutes, freeze at -5 ° C for 6 minutes, then shake at 60 ° C for 20 minutes, freeze at -5 ° C for 3 minutes, then shake at 55 ° C for 10 minutes. The third mixed liquid is obtained.

Mixing the prepared first mixed liquid with the third mixed liquid, shaking for 30 minutes to 1 hour, adding the second mixed liquid, and heating to 100-120 ° C under a pressure of 0.5 to 1.33 kPa. After 3 to 10 minutes, the temperature was lowered to 60 to 70 ° C, and the mixture was filtered to remove slag.

a surfactant, a VE derivative, an emulsifier, and a consistency adjuster are sequentially added to the mixed liquid in which the first mixed liquid, the second mixed liquid, and the third mixed liquid are remixed, and then remixed. Autoclaved, that is, long-acting bacteriostatic hand lotion.

The specific application is as follows:

Example 1

Long-acting bacteriostatic hand lotion contains the following ingredients (by mass):

Huanglian, 15 copies;

Peppermint oil, 20 parts;

Astragalus, 2 servings;

Daqingye, 2 servings;

Ai Ye essential oil, 5 parts;

Zhimu, 2 copies;

Dandelion essential oil, 10 parts;

VE derivative, 2 parts;

Emulsifier, 6 parts;

Surfactant, 0.2 parts;

Consistency adjuster, 3.8 parts;

The balance is deionized water.

The first mixed liquid is specifically prepared by taking a quantitative berberine, grinding it into a powder, distilling the mint into distilled water by using distilled water, and continuously transferring the high-temperature steam into the container containing the coptis powder within 8 days, The treated berberine is mixed with peppermint oil to form a first mixture.

The specific preparation method of the second mixed liquid is: taking a certain amount of Astragalus and Daqing leaves respectively, grinding them into powder, mixing them, and fumigation with Ai leaves essential oil for 2 days, and then immersing them in Aiye essential oil. Soak for 2 days, shake 3 times a day for 5 minutes each time to prepare a second mixture.

The prepared first mixed liquid and the third mixed liquid are remixed, and after shaking for 30 hours, the second mixed liquid is added, and heated to 100 ° C under a pressure of 0.5 kPa for 3 minutes, and then cooled to The mixture was filtered to remove slag at 60 °C.

Example 2

Huanglian, 18 copies;

Peppermint oil, 23 parts;

Huang Wei, 4 servings;

Daqingye, 4 servings;

Ai Ye essential oil, 8 parts;

Zhimu, 5 copies;

Dandelion essential oil, 13 servings;

VE derivative, 4.5 parts;

Emulsifier, 10 parts;

Surfactant, 0.5 parts;

Consistency adjuster, 6 parts;

The balance is deionized water.

The first mixed liquid is specifically prepared by taking a quantitative berberine, grinding it into a powder, distilling the mint into distilled steam by using distilled water, and continuously transferring the high-temperature steam into the container containing the coptis powder within 10 days, The treated berberine is mixed with peppermint oil to form a first mixture.

The specific preparation method of the second mixed liquid is: taking a certain amount of Astragalus and Daqing leaves respectively, grinding them into powder, mixing them, and fumigation with Ai leaves essential oil for 5 days, and then immersing them in Aiye essential oil. Soak for 5 days, shake 6 times a day for 10 minutes each time to prepare a second mixture.

The prepared first mixed liquid and the third mixed liquid are remixed, and after shaking for 1 hour, the second mixed liquid is added, and heated to 120 ° C under a pressure of 1.33 kPa for 10 minutes, and then cooled to The mixture was filtered to remove slag at 70 °C.

Example 3

Huanglian, 16 copies;

Peppermint oil, 22 parts;

Huang Wei, 3 servings;

Daqingye, 3 servings;

Ai Ye essential oil, 6 parts;

Zhimu, 3 copies;

Dandelion essential oil, 11 parts;

VE derivative, 3 parts;

Emulsifier, 8 parts;

Surfactant, 0.3 parts;

Consistency adjuster, 5 parts;

The balance is deionized water.

The first mixed liquid is specifically prepared by taking a quantitative berberine, grinding it into a powder, distilling the mint into distilled steam by using distilled water, and continuously transferring the high-temperature steam into the container containing the coptis powder within 9 days, The treated berberine is mixed with peppermint oil to form a first mixture.

The specific preparation method of the second mixed liquid is: taking a certain amount of Astragalus and Daqing leaves respectively, grinding them into powder, mixing them, and fumigation with Ai leaves essential oil for 3 days, and then immersing them in Aiye essential oil. Soak for 3 days, shake 4 times a day for 7 minutes each time to prepare a second mixture.

The prepared first mixed liquid and the third mixed liquid are remixed, and after shaking for 45 minutes, the second mixed liquid is added, and heated to 110 ° C under a pressure of 1 kPa for 6 minutes, and then cooled to 65. At °C, the mixture was filtered to remove slag.

Although the embodiments of the present invention have been disclosed as above, they are not limited to the applications listed in the specification and the embodiments, and are fully applicable to various fields suitable for the present invention, and are easily accessible to those skilled in the art. The invention is not limited to the specific details and embodiments shown herein, without departing from the scope of the appended claims.

Claims

A long-acting bacteriostatic hand lotion characterized by comprising the following ingredients (by mass fraction):

Coptis, 15 to 18 servings;

Peppermint oil, 20 to 23 parts;

Astragalus, 2 to 4 servings;

Daqingye, 2 to 4 servings;

Ai Ye essential oil, 5-8 parts;

Zhimu, 2 to 5 servings;

Dandelion essential oil, 10 to 13 servings;

VE derivative, 2 to 4.5 parts;

Emulsifier, 6-10 parts;

Surfactant, 0.2 to 0.5 parts;

Consistency adjuster, 3.8-6 parts;

The balance is deionized water;

Wherein, the coptis is dissolved in the peppermint oil to form a first mixture; the scutellaria and the scutellariae are dissolved in the essential oil of the eucalyptus oil to form a second mixture; the mother is dissolved in the dandelion essential oil to form a third mixture; the first mixture is After mixing the liquid, the second mixed liquid and the third mixed liquid, a surfactant, a VE derivative, an emulsifier and a consistency adjuster are sequentially added thereto to be remixed to obtain the long-acting bacteriostatic protection Hand lotion.
The long-acting bacteriostatic hand lotion according to claim 1, which comprises the following components (by mass fraction):

Huanglian, 15 copies;

Peppermint oil, 20 parts;

Astragalus, 2 servings;

Daqingye, 2 servings;

Ai Ye essential oil, 5 parts;

Zhimu, 2 copies;

Dandelion essential oil, 10 parts;

VE derivative, 2 parts;

Emulsifier, 6 parts;

Surfactant, 0.2 parts;

Consistency adjuster, 3.8 parts;

The balance is deionized water.
The long-acting bacteriostatic hand lotion according to claim 1, which comprises the following components (by mass fraction):

Huanglian, 18 copies;

Peppermint oil, 23 parts;

Huang Wei, 4 servings;

Daqingye, 4 servings;

Ai Ye essential oil, 8 parts;

Zhimu, 5 copies;

Dandelion essential oil, 13 servings;

VE derivative, 4.5 parts;

Emulsifier, 10 parts;

Surfactant, 0.5 parts;

Consistency adjuster, 6 parts;

The balance is deionized water.
The long-acting bacteriostatic hand lotion according to claim 1, which comprises the following components (by mass fraction):

Huanglian, 16 copies;

Peppermint oil, 22 parts;

Huang Wei, 3 servings;

Daqingye, 3 servings;

Ai Ye essential oil, 6 parts;

Zhimu, 3 copies;

Dandelion essential oil, 11 parts;

VE derivative, 3 parts;

Emulsifier, 8 parts;

Surfactant, 0.3 parts;

Consistency adjuster, 5 parts;

The balance is deionized water.
The long-acting bacteriostatic hand lotion according to any one of claims 1 to 4, wherein the VE derivative is VE acetate.
The long-acting bacteriostatic hand lotion according to claim 5, wherein the first mixed liquid is specifically prepared by taking a quantitative berberine, grinding it into a powder, and distilling the mint into distilled steam by using distilled water. The high-temperature steam is continuously introduced into the container containing the coptis powder within 8 to 10 days, and the treated berberine is mixed with the peppermint oil to form a first mixed liquid.
The long-acting bacteriostatic hand lotion according to claim 6, wherein the second mixed liquid is prepared by separately taking a certain amount of scutellaria and daqing leaves and grinding them into powder. Mix and ferment it with Ai Ye essential oil for 2 to 5 days, then soak it in the essential oil of Ai Ye, soak for 2 to 5 days, shake it 3 to 6 times a day for 5 to 10 minutes, and prepare a second mixture. .
The long-acting bacteriostatic hand lotion according to claim 7, wherein the third mixed liquid is prepared by taking a certain amount of anema, grinding it into a powder, and adding it to the dandelion essential oil. , frozen at -5 ° C for 18 minutes, then shaken at 80 ° C for 1 hour, frozen at -5 ° C for 15 minutes, then shaken at 75 ° C for 50 minutes, and frozen at -5 ° C for 12 minutes Then, shake at 40 ° C for 40 minutes, freeze at -5 ° C for 9 minutes, then shake at 65 ° C for 30 minutes, freeze at -5 ° C for 6 minutes, and then shake at 60 ° C for 20 minutes. The mixture was frozen at -5 ° C for 3 minutes and then shaken at 55 ° C for 10 minutes to obtain the third mixture.
The long-acting bacteriostatic hand lotion according to claim 8, wherein the first mixed liquid obtained and the third mixed liquid are remixed, shaken for 30 minutes to 1 hour, and then added. The second mixed liquid is heated to 100 to 120 ° C under a pressure of 0.5 to 1.33 kPa for 3 to 10 minutes, and then cooled to 60 to 70 ° C, and the mixture is filtered to remove slag.
The long-acting bacteriostatic hand lotion according to claim 9, wherein the mixture of the first mixed liquid, the second mixed liquid and the third mixed liquid is sequentially added. Surfactants, VE derivatives, emulsifiers and consistency regulators are remixed and then autoclaved to obtain a long-lasting bacteriostatic hand lotion.