WO2017044269A1 - Power internal medical devices with guided surface waves - Google Patents

Power internal medical devices with guided surface waves Download PDF

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Publication number
WO2017044269A1
WO2017044269A1 PCT/US2016/047375 US2016047375W WO2017044269A1 WO 2017044269 A1 WO2017044269 A1 WO 2017044269A1 US 2016047375 W US2016047375 W US 2016047375W WO 2017044269 A1 WO2017044269 A1 WO 2017044269A1
Authority
WO
WIPO (PCT)
Prior art keywords
guided surface
computing device
circuit
stimulus
wave
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2016/047375
Other languages
English (en)
French (fr)
Inventor
James F. Corum
Kenneth L. CORUM
Paul Kendall CARLTON
Joseph F. PINZONE
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CPG Technologies LLC
Original Assignee
CPG Technologies LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to JP2018513558A priority Critical patent/JP2018527104A/ja
Priority to NZ74138816A priority patent/NZ741388A/en
Priority to EA201890667A priority patent/EA201890667A1/ru
Priority to CA2997624A priority patent/CA2997624A1/en
Priority to MA42077A priority patent/MA42077B1/fr
Priority to AU2016320690A priority patent/AU2016320690B2/en
Priority to MX2018002880A priority patent/MX2018002880A/es
Priority to EP16760854.6A priority patent/EP3347091B1/en
Priority to KR1020187009827A priority patent/KR20180051580A/ko
Application filed by CPG Technologies LLC filed Critical CPG Technologies LLC
Priority to CN201680064906.7A priority patent/CN108348757A/zh
Priority to TW105129075A priority patent/TW201713269A/zh
Publication of WO2017044269A1 publication Critical patent/WO2017044269A1/en
Priority to IL257909A priority patent/IL257909A/en
Priority to PH12018500524A priority patent/PH12018500524A1/en
Anticipated expiration legal-status Critical
Priority to ZA2018/02273A priority patent/ZA201802273B/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/365—Heart stimulators controlled by a physiological parameter, e.g. heart potential
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/0205—Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
    • A61B5/02055—Simultaneously evaluating both cardiovascular condition and temperature
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36007—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation of urogenital or gastrointestinal organs, e.g. for incontinence control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/36128—Control systems
    • A61N1/36135—Control systems using physiological parameters
    • A61N1/36139—Control systems using physiological parameters with automatic adjustment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators
    • A61N1/37—Monitoring; Protecting
    • A61N1/3702—Physiological parameters
    • A61N1/3704—Circuits specially adapted therefor, e.g. for sensitivity control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/37211—Means for communicating with stimulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/372—Arrangements in connection with the implantation of stimulators
    • A61N1/378—Electrical supply
    • A61N1/3787—Electrical supply from an external energy source
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01P—WAVEGUIDES; RESONATORS, LINES, OR OTHER DEVICES OF THE WAVEGUIDE TYPE
    • H01P3/00—Waveguides; Transmission lines of the waveguide type
    • H—ELECTRICITY
    • H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02J—CIRCUIT ARRANGEMENTS OR SYSTEMS FOR SUPPLYING OR DISTRIBUTING ELECTRIC POWER; SYSTEMS FOR STORING ELECTRIC ENERGY
    • H02J3/00—Circuit arrangements for AC mains or AC distribution networks
    • H02J3/12—Circuit arrangements for AC mains or AC distribution networks for adjusting voltage in AC networks by changing a characteristic of the network load
    • H02J3/16—Circuit arrangements for AC mains or AC distribution networks for adjusting voltage in AC networks by changing a characteristic of the network load by adjustment of reactive power
    • H—ELECTRICITY
    • H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02J—CIRCUIT ARRANGEMENTS OR SYSTEMS FOR SUPPLYING OR DISTRIBUTING ELECTRIC POWER; SYSTEMS FOR STORING ELECTRIC ENERGY
    • H02J50/00—Circuit arrangements or systems for wireless supply or distribution of electric power
    • H02J50/10—Circuit arrangements or systems for wireless supply or distribution of electric power using inductive coupling
    • H—ELECTRICITY
    • H02—GENERATION; CONVERSION OR DISTRIBUTION OF ELECTRIC POWER
    • H02J—CIRCUIT ARRANGEMENTS OR SYSTEMS FOR SUPPLYING OR DISTRIBUTING ELECTRIC POWER; SYSTEMS FOR STORING ELECTRIC ENERGY
    • H02J50/00—Circuit arrangements or systems for wireless supply or distribution of electric power
    • H02J50/80—Circuit arrangements or systems for wireless supply or distribution of electric power involving the exchange of data, concerning supply or distribution of electric power, between transmitting devices and receiving devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
    • A61B2560/02—Operational features
    • A61B2560/0204—Operational features of power management
    • A61B2560/0214—Operational features of power management of power generation or supply
    • A61B2560/0219—Operational features of power management of power generation or supply of externally powered implanted units
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/021—Measuring pressure in heart or blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/024—Measuring pulse rate or heart rate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • A61B5/053—Measuring electrical impedance or conductance of a portion of the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Measuring devices for evaluating the respiratory organs
    • A61B5/0816—Measuring devices for examining respiratory frequency
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/103—Measuring devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
    • A61B5/1107—Measuring contraction of parts of the body, e.g. organ or muscle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14542—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring blood gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/362—Heart stimulators

Definitions

  • the geometric parameters are related by the electrical effective height (h eff ) of the charge terminal by
  • the distance to the perfectly conducting image ground plane 139 can be approximated by
  • Equation (45) through (51) Based upon the adjusted parameters of the coil 215 and the length of the vertical feed line conductor 221 , the velocity factor, phase delay, and impedance of the coil 215 and vertical feed line conductor 221 can be determined using Equations (45) through (51).
  • the self-capacitance (C T ) of the charge terminal Ti can be determined using, e.g. , Equation (24).
  • the propagation factor ( ⁇ ⁇ ) of the coil 215 can be determined using Equation (35) and the propagation phase constant ( ? w ) for the vertical feed line conductor 221 can be determined using Equation (49).
  • FIG. 1 1 shows a plot of both over a range of frequencies. As both ⁇ and ⁇ are frequency dependent, it can be seen that their respective curves cross over each other at approximately 1.85 MHz.
  • Equation (65) the impedance seen "looking down" into the lossy conducting medium 203 (i.e., Earth) can be determined as:
  • Equation (63) the impedance seen "looking up" into the vertical feed line conductor is given by Equation (63) as:
  • the probe control system 230 can adjust the self-capacitance of the charge terminal ⁇ and/or the phase delay (6 y , 6 C ) applied to the charge terminal ⁇ to maintain the electrical launching efficiency of the guided surface wave at or near its maximum.
  • the self-capacitance of the charge terminal ⁇ can be varied by changing the size of the terminal.
  • the charge distribution can also be improved by increasing the size of the charge terminal ⁇ , which can reduce the chance of an electrical discharge from the charge terminal T
  • the charge terminal Ti can include a variable inductance that can be adjusted to change the load impedance Z L .
  • the phase applied to the charge terminal can be adjusted by varying the tap position on the coil 215 (FIG. 7), and/or by including a plurality of predefined taps along the coil 215 and switching between the different predefined tap locations to maximize the launching efficiency.
  • the coil phase can be determined from Re ⁇ Oy ⁇ , as graphically illustrated in plot 175.
  • V T C e E inc - dl, (96) where E inc is the strength of the incident electric field induced on the linear probe 303 in Volts per meter, dl is an element of integration along the direction of the linear probe 303, and h e is the effective height of the linear probe 303.
  • An electrical load 315 is coupled to the output terminals 312 through an impedance matching network 318.
  • the computing device 457 may cause the stimulus circuit 451 to provide the stimulus to the human body 412.
  • the stimulus may include one or more of an electrical stimulus to a peroneal nerve, an electrical stimulus to a heart chamber, an electrical stimulus to the surface of a stomach, an electrical stimulus to an auditory nerve, an auditory stimulus to an auditory nerve, a secretion of insulin, a secretion of one or more other substances, and/or some other stimulus.
  • the monitoring circuit 454 may measure a glucose level in a body and provide the glucose level to computing device 457.
  • the medical stimulus process 475 includes providing a stimulus to the human body.
  • the computing device 457 may transmit an indication to a stimulus circuit 451 (FIG. 23) to cause the stimulus circuit 451 to provide or output a stimulus.
  • the computing device 457 may raise and/or lower a GPIO line connected to the stimulus circuit 451 to indicate that a stimulus should be provided.
  • the computing device 457 may need to transmit a message to stimulus circuit 451 with parameters describing characteristics of the stimulus to be output.
  • the stimulus circuit 451 may respond with a message confirming the instructions and the stimulus circuit 451 may require an acknowledgement from the computing device 457 before applying the stimulus.
  • the communication between the stimulus circuit 451 and the computing device 457 may be encrypted.
  • the stimulus circuit 451 provides the stimulus in response to receiving the indication from the computing device 457.
  • Clause 21 The method of any of clauses 19 and 20, further comprising: receiving, via the at least one computing device, a request to modify at least one threshold for providing the stimulus; modifying, via the at least one computing device, the at least one threshold based at least in part on the request to generate at least one modified threshold; and causing, via the at least one computing device, the stimulus circuit to provide the stimulus based in part on the at least one modified threshold.
  • Clause 22 The method of any of clauses 19-21 , further comprising: receiving, via the at least one computing device, a software package via a network connection, the software package including a hash of the software package; verifying, via the at least one computing device, the software packaged based at least in part on the hash; receiving, via the at least one computing device, a request to program the software package into a memory associated with the computing device; storing, via the at least one computing device, the software package in the memory; validating, via the at least one computing device, the software package was successfully stored; and executing, via the at least one computing device, the software package.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Power Engineering (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Electrotherapy Devices (AREA)
  • Radar Systems Or Details Thereof (AREA)
  • Control Of Motors That Do Not Use Commutators (AREA)
  • Waveguides (AREA)
  • Materials For Medical Uses (AREA)
PCT/US2016/047375 2015-09-09 2016-08-17 Power internal medical devices with guided surface waves Ceased WO2017044269A1 (en)

Priority Applications (14)

Application Number Priority Date Filing Date Title
KR1020187009827A KR20180051580A (ko) 2015-09-09 2016-08-17 유도 표면파들을 사용하는 전원 내장 의료 디바이스들
EA201890667A EA201890667A1 (ru) 2015-09-09 2016-08-17 Запитывание внутренних медицинских устройств с помощью направляемых поверхностных волн
CA2997624A CA2997624A1 (en) 2015-09-09 2016-08-17 Power internal medical devices with guided surface waves
MA42077A MA42077B1 (fr) 2015-09-09 2016-08-17 Dispositifs médicaux internes électriques avec ondes de surface guidée
AU2016320690A AU2016320690B2 (en) 2015-09-09 2016-08-17 Power internal medical devices with guided surface waves
MX2018002880A MX2018002880A (es) 2015-09-09 2016-08-17 Dispositivos medicos internos con energia con ondas superficiales guiadas.
EP16760854.6A EP3347091B1 (en) 2015-09-09 2016-08-17 Power internal medical devices with guided surface waves
JP2018513558A JP2018527104A (ja) 2015-09-09 2016-08-17 誘導表面波を用いた電力体内医療デバイス
CN201680064906.7A CN108348757A (zh) 2015-09-09 2016-08-17 具有被引导的表面波的电力内部医疗设备
NZ74138816A NZ741388A (en) 2015-09-09 2016-08-17 Power internal medical devices with guided surface waves
TW105129075A TW201713269A (en) 2015-09-09 2016-09-08 Power internal medical devices with guided surface waves
IL257909A IL257909A (en) 2015-09-09 2018-03-06 Power internal medical devices with guided surface waves
PH12018500524A PH12018500524A1 (en) 2015-09-09 2018-03-09 Power internal medical devices with guided surface waves
ZA2018/02273A ZA201802273B (en) 2015-09-09 2018-04-06 Power internal medical devices with guided surface waves

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562215868P 2015-09-09 2015-09-09
US62/215,868 2015-09-09

Publications (1)

Publication Number Publication Date
WO2017044269A1 true WO2017044269A1 (en) 2017-03-16

Family

ID=56877124

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2016/047375 Ceased WO2017044269A1 (en) 2015-09-09 2016-08-17 Power internal medical devices with guided surface waves

Country Status (18)

Country Link
US (1) US10230270B2 (enExample)
EP (1) EP3347091B1 (enExample)
JP (1) JP2018527104A (enExample)
KR (1) KR20180051580A (enExample)
CN (1) CN108348757A (enExample)
AU (1) AU2016320690B2 (enExample)
CA (1) CA2997624A1 (enExample)
CL (1) CL2018000616A1 (enExample)
EA (1) EA201890667A1 (enExample)
HK (1) HK1253568A1 (enExample)
IL (1) IL257909A (enExample)
MA (1) MA42077B1 (enExample)
MX (1) MX2018002880A (enExample)
NZ (1) NZ741388A (enExample)
PH (1) PH12018500524A1 (enExample)
TW (1) TW201713269A (enExample)
WO (1) WO2017044269A1 (enExample)
ZA (1) ZA201802273B (enExample)

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US10193229B2 (en) * 2015-09-10 2019-01-29 Cpg Technologies, Llc Magnetic coils having cores with high magnetic permeability
WO2018068013A1 (en) * 2016-10-06 2018-04-12 The Regents Of The University Of California An implantable electrocorticogram brain-computer interface system for restoring extremity movement
KR102010773B1 (ko) * 2017-07-19 2019-08-14 주식회사 워프솔루션 무선으로 전력을 공급받는 전기 자극 장치

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WO2009120490A1 (en) * 2008-03-26 2009-10-01 Medtronic, Inc. Telemetry control for implantable medical devices
US20140252886A1 (en) 2013-03-07 2014-09-11 Cpg Technologies, Llc Excitation and use of guided surface wave modes on lossy media
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