WO2016158145A1 - Ensemble aiguille d'injection et dispositif d'injection de médicament - Google Patents

Ensemble aiguille d'injection et dispositif d'injection de médicament Download PDF

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Publication number
WO2016158145A1
WO2016158145A1 PCT/JP2016/056001 JP2016056001W WO2016158145A1 WO 2016158145 A1 WO2016158145 A1 WO 2016158145A1 JP 2016056001 W JP2016056001 W JP 2016056001W WO 2016158145 A1 WO2016158145 A1 WO 2016158145A1
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WO
WIPO (PCT)
Prior art keywords
holding
needle
protector
needle tube
contact piece
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Application number
PCT/JP2016/056001
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English (en)
Japanese (ja)
Inventor
英二 川本
Original Assignee
テルモ株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by テルモ株式会社 filed Critical テルモ株式会社
Priority to JP2017509414A priority Critical patent/JP6665165B2/ja
Publication of WO2016158145A1 publication Critical patent/WO2016158145A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles

Definitions

  • the present invention relates to an injection needle assembly and a drug injection device used for puncturing a needle tip from the surface of the skin and injecting a drug into the upper layer of the skin.
  • the skin is composed of three parts: epidermis, dermis, and subcutaneous tissue.
  • the epidermis is a layer of about 50 to 200 ⁇ m from the skin surface, and the dermis is a layer of about 1.5 to 3.5 mm continuing from the epidermis. Since influenza vaccine is generally administered subcutaneously or intramuscularly, it is administered in the lower layer of the skin or deeper than that.
  • the prepanemic vaccine can be administered to more humans.
  • the upper skin layer refers to the epidermis and dermis of the skin.
  • a method using a single needle is most suitable.
  • the Manto method As a method of administering a vaccine to the upper skin layer using this single needle, the Manto method has been known for a long time.
  • a needle having a short bevel tip with a size of 26 to 27 gauge is generally inserted about 2 to 5 mm from an oblique direction of about 10 to 15 ° with respect to the skin, and about 100 ⁇ l of drug is administered. It is a method to do.
  • Patent Document 1 describes an injection device for an upper skin portion in which a limiter having a skin contact surface is connected to a needle hub.
  • the limiter described in Patent Document 1 is provided around the needle tube and has a gap with the needle tube.
  • an object of the present invention is to provide an injection needle assembly and a drug injection device that can prevent a needle tip of a needle tube from being accidentally punctured by a user after drug administration or at the time of disposal. It is in.
  • an injection needle assembly of the present invention includes a needle tube having a needle tip that can be punctured into a living body, a needle hub that holds the needle tube, a protector, and a biasing member. And a contact piece provided on the protector, a retaining member, and a holding and releasing mechanism.
  • the protector is movable to a first position where the needle tip of the needle tube is exposed and a second position covering the needle tip of the needle tube.
  • the biasing member biases the protector from the first position toward the second position along the axial direction of the needle tube.
  • the retaining member comes into contact with the contact piece when the protector moves to the second position.
  • the holding and releasing mechanism detachably holds the protector at the second position.
  • the drug injection device of the present invention includes an injection needle assembly and a syringe that is detachably attached to the injection needle assembly.
  • the injection needle assembly described above is used as the injection needle assembly.
  • the injection needle assembly and the drug injection device of the present invention it is possible to prevent the needle tip of the used needle tube from being punctured against the user's intention.
  • Embodiments of an injection needle assembly and a drug injection device according to the present invention will be described below with reference to FIGS.
  • symbol is attached
  • the present invention is not limited to the following form. The description will be given in the following order.
  • FIG. 1 is a perspective view showing the drug injection device of this example
  • FIG. 2 is a cross-sectional view showing the injection needle assembly of this example.
  • the drug injection device 1 is used when the needle tip is punctured on the surface of the skin and the drug is injected into the upper layer of the skin.
  • the drug injection device 1 includes an injection needle assembly 2, a syringe 3 that is detachably attached to the injection needle assembly 2, a pusher member 4, and a syringe holder that holds the syringe 3. 5.
  • the syringe 3 is a prefilled syringe that is filled with a medicine in advance.
  • the syringe 3 includes a syringe body 11, a discharge part formed at one end of the syringe body 11 in the axial direction, a lock mechanism 12 provided in the discharge part, and a gasket 13.
  • the syringe body 11 is formed in a hollow, substantially cylindrical shape.
  • a gasket 13 is slidably disposed in the cylindrical hole of the syringe body 11.
  • the gasket 13 is formed in a substantially cylindrical shape and is in liquid-tight contact with the inner peripheral surface of the cylindrical hole of the syringe body 11.
  • the gasket 13 partitions the internal space of the syringe body 11 into two.
  • a space closer to the discharge part than the gasket 13 in the syringe body 11 is a liquid chamber 14 filled with a medicine.
  • a plunger main body 16 of the pusher member 4 to be described later is inserted into a space on the other end side of the gasket 13 in the syringe main body 11.
  • the material of the gasket 13 is not particularly limited, but is preferably made of an elastic material in order to improve liquid tightness with the syringe body 11.
  • the elastic material include various rubber materials such as natural rubber, isobutylene rubber, and silicone rubber, various thermoplastic elastomers such as olefin and styrene, and mixtures thereof.
  • the outer diameter and inner diameter of the syringe body 11 are appropriately set according to the use of the drug injection device 1 and the volume of the drug stored in the liquid chamber 14. For example, when the volume of the medicine to be stored using a general-purpose high-speed filling machine is 0.5 mL, the inner diameter of the syringe body 11 is set to 4.4 to 5.0 mm, and the outer diameter of the syringe body 11 is set to 6. It is preferable to set to 5 to 8.4 mm. When the volume is 1 mL, it is preferable to set the inner diameter of the syringe body 11 to 6.1 to 9.0 mm and the outer diameter of the syringe body 11 to 7.9 to 12.5 mm.
  • drugs include various vaccines that prevent various infectious diseases such as influenza, but are not limited to vaccines.
  • drugs other than vaccines include glucose injection solutions such as glucose, electrolyte correction injection solutions such as sodium chloride and potassium lactate, vitamin agents, antibiotic injection solutions, contrast agents, steroid agents, and protease inhibitors Agents, fat emulsions, anticancer agents, anesthetics, heparin calcium, antibody drugs and the like.
  • a flange portion 15 is formed at the other axial end portion of the syringe body 11.
  • the flange portion 15 is locked to a locking portion 5a provided on the syringe holder 5 described later.
  • the discharge part which does not appear in a figure is continuously formed in the axial direction one end part of the syringe main body 11.
  • the discharge part is formed in a substantially cylindrical shape coaxial with the syringe body 11. Further, the cylindrical hole of the discharge portion communicates with the cylindrical hole of the syringe body 11. The discharge part is formed in a tapered shape whose diameter continuously decreases toward one end in the axial direction.
  • the lock mechanism 12 is provided in the discharge part.
  • the lock mechanism 12 is a luer lock portion showing an example of a fixing mechanism.
  • the lock mechanism 12 is formed in a cylindrical shape that surrounds the discharge portion coaxially.
  • the lock mechanism 12 has a circular inner periphery and a hexagonal outer periphery.
  • An internal thread portion is formed on the inner peripheral surface of the lock mechanism 12.
  • the female screw part is formed so as to be screwable with a male screw part 52 b provided in the injection needle assembly 2.
  • Examples of the material of the syringe body 11 include polyvinyl chloride, polyethylene, polypropylene, cyclic polyolefin, polystyrene, poly- (4-methylpentene-1), polycarbonate, acrylic resin, acrylonitrile-butadiene-styrene copolymer, polyethylene.
  • Various resins such as polyester such as terephthalate, butadiene-styrene copolymer, polyamide (for example, nylon 6, nylon 6,6, nylon 6,10, nylon 12) can be used.
  • the material of the syringe main body 11 is substantially transparent in order to ensure internal visibility.
  • the syringe holder 5 is formed in a substantially cylindrical shape.
  • the syringe holder 5 covers the outer peripheral surface of the syringe body 11 and the outer peripheral surface of the lock mechanism 12 in the syringe 3.
  • the syringe holder 5 is configured to be gripped by the user when attaching the injection needle assembly 2 to the syringe 3.
  • a viewing window 18 is formed at one end of the syringe holder 5 in the axial direction.
  • the viewing window 18 is provided at a position where the liquid chamber 14 of the syringe 3 is visible from the outside of the syringe holder 5 when the syringe 3 is mounted on the syringe holder 5. Thereby, even if the syringe holder 5 is attached to the syringe 3, the internal visibility can be ensured.
  • a holder collar 19 is formed at the other end of the syringe holder 5 in the axial direction.
  • the holder collar 19 protrudes substantially perpendicularly from a part of the outer peripheral surface of the syringe holder 5.
  • a locking part 5 a is provided in the middle part of the syringe holder 5 in the axial direction.
  • the locking portion 5 a is an opening that penetrates the outer wall of the syringe holder 5.
  • the flange portion 15 of the syringe 3 is locked to the locking portion 5a.
  • the diameter of the drug injection device 1 can be increased and the drug injection device 1 can be easily held. Thereby, the operativity at the time of operating the pusher member 4 improves.
  • the pusher member 4 includes a plunger main body 16, an operation portion 17 that operates the plunger main body 16, and a pressing member 20 that presses a holding / maintaining portion 42 of the injection needle assembly 2 described later.
  • the plunger body 16 is formed in a rod shape.
  • the plunger main body 16 is inserted into the cylindrical hole of the syringe main body 11 through an opening formed at the other axial end of the syringe main body 11.
  • One end portion of the plunger body 16 in the axial direction is in contact with the gasket 13.
  • the operation unit 17 is formed at the other end of the plunger body 16 in the axial direction.
  • the operation unit 17 is formed in a substantially disk shape.
  • the operation unit 17 is pressed by the user. Thereby, the one end part of the axial direction of the plunger main body 16 contact
  • the pressing member 20 is formed in a rod shape.
  • the pressing member 20 is connected to the other end portion of the plunger main body 16 in the axial direction via a connection portion that does not appear in the drawing.
  • the axial direction of the pressing member 20 extends substantially parallel to the axial direction of the plunger body 16.
  • the plunger main body 16 is provided with a protrusion or a flange-shaped member integrally formed therewith, and a connection portion of the pressing member 20 is connected thereto, or a hole through which the plunger main body 16 is inserted is provided.
  • a method of connecting portion of the pressing member 20 to a disk-shaped member in which movement in the direction of the operation unit 17 by such a protrusion or a flange-shaped member is restricted can be cited.
  • the pressing member 20 is disposed in a gap formed between the cylindrical hole of the syringe holder 5 in the syringe holder 5 and the syringe body 11 of the syringe 3. And the one end part of the axial direction of the press member 20 protrudes from the end of the axial direction of the syringe holder 5, and opposes the holding
  • the pressing member 20 moves along with the plunger body 16 along the axial direction.
  • the injection needle assembly 2 includes a hollow needle tube 21 and a needle hub 22 that holds the needle tube 21.
  • the needle tube 21 is a size of 26 to 33 gauge (outer diameter 0.2 to 0.45 mm) based on the ISO medical needle tube standard (ISO9626: 1991 / Amd.1: 2001 (E)). And preferably 30 to 33 gauge. A needle thinner than 33 gauge may be used.
  • a needle tip 21a having a blade surface is provided at one end of the needle tube 21, a needle tip 21a having a blade surface is provided.
  • the other end of the needle tube 21 opposite to the needle tip 21a is referred to as a “base end”.
  • the length of the needle tube 21 in the axial direction on the blade surface (hereinafter referred to as “bevel length”) may be 1.4 mm (adult) or less, which is the thinnest thickness of the upper skin layer described later, and 33 What is necessary is just about 0.5 mm or more which is the bevel length when a short bevel is formed in the needle tube of a gauge. That is, the bevel length is preferably set in the range of 0.5 to 1.4 mm.
  • the bevel length is further preferably such that the thinnest thickness of the upper skin layer is 0.9 mm (child) or less, that is, the bevel length is in the range of 0.5 to 0.9 mm.
  • the short bevel refers to a blade surface that is generally used for injection needles and forms an angle of 18 to 25 ° with respect to the longitudinal direction of the needle.
  • the needle tube 21 examples include stainless steel, but are not limited thereto, and aluminum, aluminum alloy, titanium, titanium alloy, and other metals can be used.
  • the needle tube 21 may be a straight needle or a tapered needle having at least a part that is tapered. As the taper needle, the proximal end portion has a larger diameter than the needle distal end portion, and the intermediate portion may have a tapered structure. Further, the cross-sectional shape of the needle tube 21 may be not only a circle but also a polygon such as a triangle.
  • the needle hub 22 includes a first member 23 that holds the needle tube 21, a second member 24 into which the discharge portion of the syringe 3 is inserted, an elastic member 25, a protector 26, a biasing member 27, and a holding member 41.
  • the holding / maintaining unit 42 is provided.
  • the first member 23 and the second member 24 are formed as separate members. Examples of the material of the first member 23 and the second member 24 include synthetic resins such as polycarbonate, polypropylene, and polyethylene.
  • the first member 23 includes a base part 31, an adjustment part 32, a stabilization part 33, a guide part 34, and a support part 37.
  • the base part 31 is formed in a substantially cylindrical shape.
  • An accommodation recess 36 is formed in the base portion 31.
  • the housing recess 36 is formed to be recessed in a substantially cylindrical shape from one end to the other end of the base portion 31 in the axial direction. The entire end of the axial end of the base portion 31 is open.
  • a support portion 37 is provided in the housing recess 36.
  • the support portion 37 is provided at the center of the bottom surface 36 a of the housing recess 36, and protrudes from the bottom surface 36 a of the housing recess 36 toward one side in the axial direction of the base portion 31.
  • the support part 37 is formed in a substantially cylindrical shape.
  • an adjustment portion 32 is continuously provided on one end surface of the support portion 37 in the axial direction, and the adjustment portion 32 is formed of a columnar convex portion protruding in the axial direction of the support portion 37.
  • the axis of the adjustment part 32 is coincident with the axis of the base part 31 and the support part 37.
  • first openings 38, 38 facing each other are formed on the side wall of the base portion 31.
  • the two first openings 38, 38 penetrate the side wall of the base portion 31 to the accommodation recess 36.
  • a holding / maintaining portion 42 described later is inserted into the two first openings 38 and 38 so as to be slidable along the axial direction of the base portion 31.
  • a through hole 39 through which the needle tube 21 passes is provided in the shaft center of the base portion 31, the support portion 37 and the adjustment portion 32.
  • the base portion 31 is provided with an injection hole 44 for injecting an adhesive into the through hole 39.
  • the injection hole 44 is opened on the outer peripheral surface of the base portion 31 on the other side in the axial direction from the housing recess 36, and communicates with the through hole 39. That is, the needle tube 21 is fixed to the base portion 31 and the support portion by the adhesive material injected from the injection hole 44 to the through hole 39.
  • the proximal end side of the needle tube 21 protrudes from the end surface 31 a on the other side in the axial direction of the base portion 31.
  • the base portion 31 is inserted into the second member 24 from the end surface 31a, and the proximal end side of the needle tube 21 is inserted through the insertion hole of the elastic member 25.
  • the end surface 31 a of the base portion 31 faces the end surface of the elastic member 25.
  • connection piece 35 is provided on the outer peripheral surface of the base portion 31.
  • the connection piece 35 is formed as a ring-shaped flange portion that protrudes outward in the radial direction of the base portion 31 on one end side in the axial direction of the base portion 31.
  • the connecting piece 35 has flat surfaces 35 a and 35 b that face the axial direction of the base portion 31.
  • the second member 24 is connected to the flat surface 35 b of the connection piece 35.
  • the distal end portion of the connection piece 35 is a guide portion 34. The guide part 34 will be described in detail later.
  • the end surface of the adjusting portion 32 is a needle projecting surface 32a from which the needle tip 21a side of the needle tube 21 projects.
  • the needle projecting surface 32 a is formed as a plane orthogonal to the axial direction of the needle tube 21.
  • This needle protruding surface 32a defines the depth of puncturing the needle tube 21 in contact with the surface of the skin when the needle tube 21 is punctured into the upper skin portion. That is, the depth at which the needle tube 21 is punctured into the upper skin layer is determined by the length of the needle tube 21 protruding from the needle protruding surface 32a (hereinafter referred to as “projection length L”) (see FIG. 3).
  • the thickness of the upper skin portion corresponds to the depth from the skin surface to the dermis layer, and is generally in the range of 0.5 to 3.0 mm. Therefore, the protruding length L of the needle tube 21 can be set in the range of 0.5 to 3.0 mm.
  • the administration site of influenza vaccine is generally the deltoid muscle. Therefore, the thickness of the upper layer of the deltoid muscle was measured for 19 children and 31 adults. This measurement was performed by imaging the upper layer of the skin with high ultrasonic reflectivity using an ultrasonic measurement device (NP60R-UBM, high-resolution echo for small animals, Nepagene). In addition, since the measured value was logarithmic normal distribution, the range of MEAN ⁇ 2SD was obtained by geometric mean.
  • the thickness of the upper skin layer of the deltoid muscle of the child was 0.9 to 1.6 mm.
  • the thickness of the upper skin layer of the deltoid muscle of adults was 1.4 to 2.6 mm at the distal part, 1.4 to 2.5 mm at the central part, and 1.5 to 2.5 mm at the proximal part. It was. From the above, it was confirmed that the thickness of the upper skin layer in the deltoid muscle was 0.9 mm or more in the case of children and 1.4 mm or more in the case of adults. Therefore, in the injection in the upper layer portion of the deltoid muscle, it is preferable that the protruding length L of the needle tube 21 is set in the range of 0.9 to 1.4 mm.
  • the blade surface of the needle tip 21a can be positioned on the upper skin layer.
  • the needle hole (medicine discharge port) that opens in the blade surface is located in the upper layer of the skin regardless of the position in the blade surface. Even if the medicine discharge port is located in the upper skin part, if the needle tip 21a is stabbed deeper than the upper skin part, the medicine flows into the subcutaneous tissue from between the side surface of the end of the needle tip 21a and the cut skin. Therefore, it is important to ensure that the blade surface is in the upper layer of the skin.
  • the needle projecting surface 32a of the adjusting portion 32 is formed such that the distance S from the peripheral edge to the outer peripheral surface of the needle tube 21 is 1.4 mm or less, preferably in the range of 0.3 to 1.4 mm.
  • the distance S from the peripheral edge of the needle protruding surface 32a to the peripheral surface of the needle tube 21 is set in consideration of the pressure applied to the blisters formed by administering the drug to the upper skin layer. That is, the needle projecting surface 32a is set to a size that is sufficiently smaller than the blisters formed on the upper layer portion of the skin and does not hinder the formation of blisters. As a result, even if the needle protruding surface 32a presses the skin around the needle tube 21, it is possible to prevent the administered medicine from leaking.
  • the stabilizing part 33 is formed in a cylindrical shape protruding from the flat surface 35a of the connecting piece 35.
  • a needle tube 21, an adjustment unit 32, and a protector 26 described later are disposed in the cylindrical hole of the stabilization unit 33. That is, the stabilizing portion 33 is formed in a cylindrical shape that covers the periphery of the adjusting portion 32 and the protector 26 through which the needle tube 21 penetrates, and is provided away from the needle tip 21a of the needle tube 21 in the radial direction.
  • the end surface 33a of the stabilizing portion 33 is located closer to the proximal end side of the needle tube 21 than the needle protruding surface 32a of the adjusting portion 32.
  • the needle projecting surface 32a first contacts the skin surface, and then the end surface 33a of the stabilizing portion 33 contacts the skin surface.
  • the drug injection device 1 is stabilized by the end surface 33a of the stabilizing portion 33 coming into contact with the skin, and the needle tube 21 can be maintained in a posture substantially perpendicular to the skin.
  • the end surface 33a of the stabilizing portion 33 is positioned on the same plane as the needle protruding surface 32a, or is positioned closer to the needle tip 21a side of the needle tube 21 than the needle protruding surface 32a, the needle tube 21 is skinned. It is possible to keep the posture substantially perpendicular to the angle.
  • the axial distance between the end surface 33a of the stable portion 33 and the needle protruding surface 32a is preferably set to 1.3 mm or less.
  • the inner diameter d of the stable portion 33 is set to a value equal to or larger than the diameter of the blister formed on the skin.
  • the distance T from the inner wall surface of the stabilizing portion 33 to the peripheral edge of the needle protruding surface 32a is set to be in the range of 4 mm to 15 mm.
  • the distance T from the inner wall surface of the stabilizing portion 33 to the needle protruding surface 32a is not particularly limited as long as it is 4 mm or more. However, when the distance T is increased, the outer diameter of the stable portion 33 increases, so that it is difficult to bring the entire end surface 33a of the stable portion 33 into contact with the skin when the needle tube 21 is punctured into a thin arm like a child. . For this reason, the distance T is preferably set to 15 mm as a maximum in consideration of the thinness of the child's arm.
  • the adjusting unit 32 does not enter the skin. Therefore, in consideration of the distance T (4 mm or more) from the inner wall surface of the stable portion 33 to the periphery of the needle protruding surface 32a and the diameter (about 0.3 mm) of the needle protruding surface 32a, the inner diameter d of the stable portion 33 is 9 mm or more.
  • the shape of the stable part 33 is not limited to a cylindrical shape, and may be formed in a rectangular cylinder shape such as a quadrangular column or a hexagonal column having a cylindrical hole at the center.
  • the guide portion 34 is a tip side portion located on the outer side in the radial direction of the first member 23 relative to the stabilizing portion 33 in the connection piece 35.
  • the guide part 34 has the contact surface 34a which contacts skin.
  • the contact surface 34 a is a part of the flat surface 35 a of the connection piece 35 and is a flat surface that is substantially parallel to the end surface 33 a of the stabilizing portion 33.
  • the distance Y from the contact surface 34a of the guide part 34 to the end face 33a of the stable part 33 punctures the needle tube 21 and the stable part 33 by pressing the skin with an appropriate pressing force. Its length is set so that it can.
  • An appropriate pressing force of the needle tube 21 and the stabilizing portion 33 is, for example, 3 to 20N.
  • the guide portion height Y is appropriately determined based on the inner diameter d of the stable portion 33 and the length X from the distal end surface of the guide portion 34 to the outer peripheral surface of the stable portion 33 (hereinafter referred to as “guide portion length”).
  • guide portion length the guide portion height Y is set in the range of 2.3 to 6.6 mm.
  • the protector 26 covers the periphery of the adjustment portion 32 through which the needle tube 21 penetrates before the needle tube 21 is punctured into the skin. Further, the needle tip 21 a side of the needle tube 21 protrudes from the tip end surface 26 a at one end of the protector 26 in the axial direction, and the needle tip 21 a of the needle tube 21 is exposed. The position of the protector 26 at this time is defined as a first position.
  • the protector 26 is formed in a cylindrical shape.
  • the protector 26 is supported by the support portion 37 and the retaining member 43 so as to be movable in these axial directions (the axial direction of the needle tube 21).
  • a part of the protector 26 on the other side in the axial direction is inserted into a space 40 formed between the housing recess 36 and the support portion 37.
  • the protector 26 covers the periphery of the adjustment portion 32 and the needle tip 21a of the needle tube 21 (see FIG. 3).
  • the position of the protector 26 at this time is defined as a second position.
  • a contact piece 29 is provided on the side of the protector 26 opposite to the needle tip 21a of the needle tube 21, that is, the other end in the axial direction.
  • the contact piece 29 is formed as a ring-shaped flange portion that protrudes outward from the outer peripheral surface of the protector 26 in the radial direction.
  • An inclined surface 29 a is provided on the outer edge of the contact piece 29 in the radial direction.
  • the inclined surface 29 a is provided at the corner on the needle tip 21 a side of the needle tube 21 at the outer edge of the contact piece 29.
  • the inclined surface 29a is formed in a tapered shape having a diameter that continuously decreases from the other side in the axial direction toward one side.
  • a holding member 41 is disposed on the other side of the protector 26 in the axial direction.
  • the shape of the protector 26 is not limited to a cylindrical shape, and may be formed in a rectangular cylinder shape such as a rectangular column or a hexagonal column having a cylindrical hole at the center, for example. Furthermore, although the example which formed the contact piece 29 as a ring-shaped flange part was demonstrated, it is not limited to this, For example, several protrusion which protrudes toward the outer side of a radial direction from the outer peripheral surface of the protector 26 You may form as.
  • the urging member 27 is disposed in a space 40 formed in the housing recess 36, and is interposed between the other end surface of the protector 26 in the axial direction and the bottom surface 36 a of the housing recess 36.
  • the biasing member 27 is disposed so as to cover the periphery of the outer peripheral surface of the support portion 37.
  • the urging member 27 is a compression coil spring and urges the protector 26 from the first position toward the second position, that is, toward the needle tip 21 a of the needle tube 21.
  • the urging force of the urging member 27 is set to be smaller than an appropriate pressing force when the needle tube 21 is punctured into the skin, and is set to 3N or less, for example.
  • the biasing force of the biasing member 27 does not cause the needle tip 21a of the needle tube 21 from being positioned on the upper skin portion of the skin.
  • the tip 21a can be positioned in the upper layer portion of the skin.
  • the urging member may be an elastic member that elastically deforms when a predetermined pressing force is applied.
  • various other spring members such as a leaf spring, sponge, gel, and rubber member can be applied.
  • the holding member 41 has a cylindrical portion 45 formed in a substantially cylindrical shape and a plurality of holding portions 46.
  • the holding member 41 is disposed in the housing recess 36.
  • the cylindrical portion 45 is fixed to the bottom surface 36 a of the housing recess 36.
  • the holding member 41 is arrange
  • a plurality of holding portions 46 are continuously formed on one side of the cylindrical portion 45 in the axial direction.
  • the plurality of holding portions 46 are provided on one end surface of the cylindrical portion 45 in the axial direction with a predetermined interval along the circumferential direction.
  • the plurality of holding portions 46 protrude from the one end surface in the axial direction of the cylindrical portion 45 in a substantially flat plate shape.
  • maintenance part 46 is formed in the shape of a tongue piece, and the elasticity is provided.
  • the distal end portion of the holding portion 46 is inclined with respect to the axial direction of the needle tube 21 so as to be closer to the inner side in the radial direction than the base end portion on the cylindrical portion 45 side, that is, to the support portion 37.
  • Locking pieces 46 a are provided on the inner surfaces in the radial direction at the tips of the plurality of holding portions 46. The locking piece 46a protrudes substantially vertically from the inner surface of the holding portion 46 to the inner side in the radial direction.
  • the plurality of holding portions 46 are locked to the contact pieces 29 of the protector 26.
  • maintenance part 46 resists the urging
  • holding diameter the diameter of the space formed by the plurality of holding portions 46 when the plurality of holding portions 46 are in a natural state without elastic deformation (hereinafter referred to as “holding diameter”) is outside the contact piece 29 of the protector 26. It is set slightly larger than the diameter.
  • the holding member 42 is detachably attached to the holding member 41.
  • the holding / maintaining portion 42 is formed in a substantially flat plate shape.
  • a restriction hole 47 is formed in the holding / maintaining portion 42.
  • the restriction hole 47 is formed in the substantially central portion of the holding / maintaining portion 42.
  • the opening diameter of the restriction hole 47 is set larger than the outer diameter of the contact piece 29 of the protector 26.
  • the cylindrical portion and the support portion 37 of the protector 26 are inserted into the restriction hole 47. Furthermore, in the state shown in FIG. 2, the front-end
  • the restriction hole 47 biases the plurality of holding portions 46 inward in the radial direction. Therefore, the plurality of holding portions 46 are elastically deformed so as to rotate with the base end portion on the cylindrical portion 45 side as a fulcrum. As a result, the holding diameters of the plurality of holding portions 46 are reduced by the restriction holes 47.
  • both end portions of the holding / maintaining portion 42 sandwiching the restriction hole 47 are inserted into a first opening 38 provided in the base portion 31 and a second opening 55 provided in a second member described later.
  • the holding / maintaining portion 42 is supported by the base portion 31 and the second member so as to be movable along the axial direction of the needle tube 21. At this time, the surface of the holding / maintaining portion 42 provided with the restriction hole 47 intersects the axial direction of the needle tube 21.
  • the holding member 41 and the holding and maintaining unit 42 described above constitute a holding and releasing mechanism.
  • the first member 23 has a retaining member 43.
  • the retaining member 43 is formed in a substantially disk shape.
  • the retaining member 43 is fixed to the base portion 31 so as to close an opening on one side in the axial direction of the housing recess 36.
  • a support hole 43 a is opened at the center of the retaining member 43.
  • the adjustment part 32, the support part 37, and the protector 26 are inserted through the support hole 43a.
  • the retaining member 43 supports the protector 26 so as to be movable along the axial direction of the support portion 37.
  • the contact piece 29 of the protector 26 contacts the other end surface of the retaining member 43 in the axial direction before the needle tube 21 is punctured into the skin. Thereby, it is possible to prevent the protector 26 urged by the urging member 27 from falling off from the first member 23.
  • the second member 24 is formed in a cylindrical shape.
  • One end portion of the second member 24 in the axial direction is an insertion portion 51 into which the base portion 31 of the first member 23 is inserted, and the other end portion is an insertion portion 52 into which the discharge portion of the syringe 3 is inserted.
  • the cylindrical hole 51 a of the insertion portion 51 is set to a size corresponding to the base portion 31 of the first member 23.
  • a fixing piece 54 is provided on the outer peripheral surface of one end portion of the second member 24 in the insertion portion 51 in the axial direction.
  • the fixed piece 54 is formed as a ring-shaped flange that protrudes outward in the radial direction continuously to the distal end of the insertion portion 51.
  • a flat surface 35b of the connection piece 35 provided on the first member 23 comes into contact with and is fixed to the fixed piece 54.
  • Examples of the fixing method of the fixing piece 54 and the connecting piece 35 include an adhesive, ultrasonic welding, laser welding, and a fixing screw.
  • the second opening portions 55 and 55 facing each other are formed on the side wall of the insertion portion 51.
  • the second opening 55 is formed at a position facing the first opening 38 formed in the base portion 31 when the base portion 31 is inserted into the insertion portion 51.
  • the 2nd opening part 55 has penetrated the side wall of the insertion part 51 to the cylinder hole 51a.
  • the holding / maintaining part 42 is inserted so as to be movable along the axial direction of the insertion part 51.
  • the outer diameter of the insertion portion 52 is set smaller than the outer diameter of the insertion portion 51. Furthermore, the cylinder hole 52a of the insertion part 52 is set to a size corresponding to the discharge part of the syringe 3, and the diameter continuously decreases toward the insertion part 51 side. Moreover, the external thread part 52b for screwing together with the locking mechanism 12 of the syringe 3 is provided in the outer peripheral surface of the insertion part 52 (refer FIG. 1). An elastic member 25 is disposed between the cylindrical hole 51 a of the insertion portion 51 and the cylindrical hole 52 a of the fitting portion 52.
  • the elastic member 25 is a member that can be elastically deformed.
  • Examples of the material of the elastic member 25 include various rubber materials such as natural rubber, silicone rubber, and isobutylene rubber, various thermoplastic elastomers such as polyurethane and styrene, or elastic materials such as a mixture thereof. .
  • the elastic member 25 is disposed in the second member 24 and is interposed between the first member 23 and the syringe 3. Then, a gap generated between the outer peripheral surface on the proximal end side of the needle tube 21 protruding from the first member 23 and the second member 24 is filled. And when the discharge part of the syringe 3 is inserted in the 2nd member 24, the elastic member 25 adheres to the outer peripheral surface of the needle tube 21 liquid-tightly by elastically deforming. Thereby, it is possible to prevent the medicine filled in the syringe 3 from penetrating between the needle tube 21 and the elastic member 25 and leaking to the first member 23 side.
  • FIG. 3 is a cross-sectional view showing the main part of the drug injection device 1 during puncturing
  • FIG. 4 is a cross-sectional view showing the main part of the drug injection device 1 after puncturing.
  • the syringe 3 is attached to the injection needle assembly 2 in advance. Specifically, the discharge part of the syringe 3 is inserted into the fitting part 52 of the second member 24, and the lock mechanism 12 is screwed into the male screw part 52b. Thereby, mounting
  • the holding and maintaining part 42 is disposed on the proximal end side in the axial direction of the needle tube 21 in the first opening 38 and the second opening 55.
  • a plurality of holding portions 46 are inserted into the restriction holes 47 of the holding / maintaining portion 42.
  • the plurality of holding portions 46 are urged by the restriction holes 47, and the holding diameters are reduced.
  • the contact piece 29 of the protector 26 is locked to the locking pieces 46 a of the plurality of holding portions 46.
  • the protector 26 is held by the holding member 41 at the first position where the needle tip 21a of the needle tube 21 is exposed. Further, the urging member 27 is compressed by being elastically deformed between the other end portion in the axial direction of the protector 26 and the bottom surface 36 a of the housing recess 36.
  • the end surface 33a of the stabilizing portion 33 is made to face the skin. Thereby, the needle tip 21a of the needle tube 21 is opposed to the skin to be punctured.
  • the drug injection device 1 is moved substantially perpendicularly to the skin, the needle tip 21a is punctured into the skin, and the end surface 33a of the stabilizing portion 33 is pressed against the skin.
  • the needle protruding surface 32a can come into contact with the skin to deform the skin flatly, and the needle tip 21a side of the needle tube 21 can be punctured into the skin by the protruding length L.
  • the end surface 33a of the stabilizing portion 33 is pressed until the contact surface 34a of the guide portion 34 contacts the skin.
  • the length of the guide portion height Y (see FIG. 2) is set so that the needle tube 21 and the stabilizing portion 33 can puncture the skin with an appropriate pressing force. Therefore, the force that presses the skin by the stabilizing portion 33 becomes a predetermined value.
  • the user can recognize an appropriate pressing force of the stable portion 33, and the needle tip 21a and the blade surface of the needle tube 21 can be surely positioned on the upper skin portion.
  • the guide part 34 becomes a mark for recognizing an appropriate pressing force of the stable part 33, so that the user can use the medicine injection device 1 with peace of mind.
  • the stabilizing portion 33 contacts the skin, the posture of the drug injection device 1 is stabilized, and the needle tube 21 can be punctured straight to the skin. Moreover, the blurring which arises in the needle tube 21 after puncture can be prevented, and the administration of the medicine can be performed stably.
  • the needle tip may not pierce the skin even if it is brought into contact with the skin.
  • the skin pressed against the stable portion 33 is pushed down in the vertical direction, the skin inside the stable portion 33 is pulled and tension is applied to the skin. Therefore, it is difficult for the skin to escape from the needle tip 21 a of the needle tube 21. Therefore, by providing the stabilizing portion 33, it is possible to obtain an effect that the needle tip 21a is more easily pierced into the skin.
  • the pusher member 4 (see FIG. 1) is pressed to move the gasket 13 to the discharge portion side.
  • the medicine filled in the liquid chamber 14 of the syringe 3 is pushed out from the discharge part, and is injected into the upper skin part from the needle tip 21 a through the needle hole of the needle tube 21.
  • the remaining amount of the medicine can be reduced.
  • the pressing member 20 moves together with the plunger body 16 toward the needle tip 21a side of the needle tube 21.
  • the holding / maintaining portion 42 is pressed by the pressing member 20 and moves toward the needle tip 21 a side of the needle tube 21. Therefore, the plurality of holding portions 46 come out of the restriction holes 47 of the holding and maintaining portion 42. When coming out of the restriction hole 47, the plurality of holding portions 46 are restored to their original shape (natural state) by their own elasticity, and the holding diameter is expanded. Thereby, holding
  • the holding diameters of the plurality of holding portions 46 are configured to be deformable into a holding state in which the contact piece 29 of the protector 26 is held and a passing state in which the contact piece 29 of the protector 26 can pass.
  • the drug injection device 1 is separated from the skin, and the end surface 33a of the stabilizing portion 33, the needle protruding surface 32a, and the tip surface 26a of the protector 26 are separated from the skin.
  • the protector 26 is biased toward the needle tip 21 a side of the needle tube 21 by the restoring force (biasing force) of the biasing member 27. Therefore, the protector 26 is supported by the outer peripheral surface of the support portion 37 and the support hole 43a of the retaining member 43, and is moved from the other side in the axial direction of the support portion 37 to one side, that is, from the first position to the second position. Move towards.
  • the size of the holding diameter in the natural state of the plurality of holding portions 46 is set larger than the outer diameter of the contact piece 29 of the protector 26. Therefore, when the contact piece 29 of the protector 26 passes through the locking pieces 46a of the plurality of holding portions 46, the protector 26 can be moved smoothly without the contact pieces 29 being caught by the locking pieces 46a. .
  • the contact piece 29 is in contact with the retaining member 43, so that movement of the protector 26 in one axial direction is restricted. Thereby, it is possible to prevent the protector 26 from falling off the support portion 37 of the first member 23.
  • the protector 26 covers the periphery of the needle tip 21 a of the needle tube 21, and the needle tube 21 is accommodated in the protector 26. That is, the protector 26 moves from the first position to the second position. Accordingly, the protector 26 can be automatically moved in accordance with the puncturing operation, and the periphery of the needle tip 21a of the needle tube 21 can be easily covered. As a result, the needle tip 21a of the used needle tube 21 can be kept in a safe state, and the needle tip 21a of the used needle tube 21 can be prevented from being punctured against the intention of the user.
  • the needle tip 21a of the used needle tube 21 is covered with the protector 26, the blood adhering to the needle tip 21a can be prevented from being scattered and infection by blood can also be prevented.
  • the support portion 37 may be provided with a return restricting portion that locks with the protector 26 and restricts the movement of the protector 26 to the first position.
  • the needle tip 21a of the needle tube 21 after puncturing can be prevented from protruding from the distal end surface 26a of the protector 26 again.
  • the holding diameter of the plurality of holding portions 46 may be set to be slightly smaller than the outer diameter of the contact piece 29. In this case, when the contact piece 29 passes through the plurality of holding portions 46, the inclined surface 29 a provided on the contact piece 29 comes into contact with the locking pieces 46 a of the plurality of holding portions 46.
  • the inclined surface 29a is formed in a tapered shape whose diameter continuously decreases from the other side in the axial direction toward one side. Therefore, the plurality of holding portions 46 are pressed toward the outside in the radial direction, and the holding diameters of the plurality of holding portions 46 are increased. Thereby, the contact piece 29 can pass between the plurality of holding portions 46 without being caught by the plurality of holding portions 46. Further, when passing through the contact piece 29, the pressing force against the plurality of holding portions 46 is released, and the plurality of holding portions 46 are restored to their original shape (natural state) by their own elasticity.
  • the corner of the abutting piece 29 opposite to the inclined surface 29a is set at a substantially right angle. Therefore, when the protector 26 is pressed from one side in the axial direction of the support part 37 toward the other side, the contact piece 29 comes into contact with the plurality of holding parts 46 of the holding member 41 and the holding diameter is increased. There is nothing. Therefore, even with such a configuration, it is possible to restrict movement of the protector 26 after puncturing from one side in the axial direction to the other side, that is, returning from the second position to the first position. Thereby, the needle tip 21a of the needle tube 21 after puncturing can be prevented from protruding from the distal end surface 26a of the protector 26 again.
  • FIG. 4 is a cross-sectional view showing a state before puncturing.
  • the difference between the drug injection device according to the second embodiment and the drug injection device 1 according to the first embodiment is the configuration of the holding part and the holding release part in the injection needle assembly. Therefore, here, the holding unit and the holding release unit will be mainly described, and the same reference numerals are given to the parts common to the injection needle assembly 2 according to the first embodiment, and the duplicated description is omitted. To do.
  • the injection needle assembly 60 includes a hollow needle tube 21 and a needle hub 62 that holds the needle tube 21.
  • the needle hub 62 includes a first member 63, a second member 64 into which the discharge portion of the syringe 3 is inserted, an elastic member 25, a protector 66, a biasing member 67, and a holding and releasing mechanism 79. Yes.
  • the first member 63 includes a base portion 71, an adjustment portion 72, a stabilization portion 73, a guide portion 74, and a support portion 77.
  • the base part 71 is formed in a substantially cylindrical shape.
  • An accommodation recess 76 is formed in the base portion 71. The entire surface of one end of the base portion 71 in the axial direction is open.
  • the housing recess 76 is formed to be recessed in a substantially cylindrical shape from one end to the other end of the base portion 71 in the axial direction.
  • a support portion 77 is formed in the housing recess 76.
  • the base portion 71 is formed with two first openings 78 and 78 that face each other.
  • the two first openings 78 penetrate the side wall of the base portion 71 to the accommodation recess 76.
  • a holding member 81 of a holding and releasing mechanism 79 described later is inserted into the two first openings 78 so as to be slidable along a direction perpendicular to the axial direction of the base portion 31.
  • the protector 66 is formed in a cylindrical shape, and has a contact piece 69 at the other end in the axial direction.
  • An urging member 67 is disposed between the other end portion of the protector 66 in the axial direction and the bottom surface 76 a of the housing recess 76.
  • the first member 63 has a retaining member 86.
  • the retaining member 86 is formed in a substantially disk shape, and a support hole 86a is opened at the center thereof.
  • the adjustment portion 72, the support portion 77, and the protector 66 are inserted through the support hole 86a.
  • the retaining member 86 supports the protector 66 so as to be movable along the axial direction of the support portion 77.
  • the 2nd member 64 has the insertion part 91 in which the base part 71 is inserted, and the insertion part 92 in which the discharge part of the syringe 3 is inserted.
  • Two second openings 95, 95 facing each other are formed on the side wall of the insertion portion 91.
  • the second opening 95 is formed at a position facing the first opening 78 formed in the base portion 71 when the base portion 71 is inserted into the insertion portion 91.
  • the 2nd opening part 95 has penetrated the side wall of the insertion part 91 to the cylinder hole 91a.
  • a holding member 81 of a holding and releasing mechanism 79 described later is inserted into the second opening 95 so as to be slidable along a direction orthogonal to the axial direction of the insertion portion 91.
  • the holding and releasing mechanism 79 includes a holding member 81, an urging portion 87, and an operation plate 88.
  • the holding member 81 is formed in a substantially flat plate shape.
  • the holding member 81 is inserted into the first opening 78 of the base portion 71 and the second opening 95 of the insertion portion 91.
  • the holding member 81 is slidably supported along the direction orthogonal to the axial direction of the needle tube 21 by the first opening 78 and the second opening 95.
  • an opening hole 82 into which the protector 66 can be inserted is provided at a substantially central portion of the holding member 81.
  • FIG. 5 is a plan view showing the holding member 81.
  • the opening hole 82 has a small-diameter opening 82a and a large-diameter opening 82b.
  • the large-diameter opening 82b is formed continuously from the outer edge of the small-diameter opening 82a.
  • the large-diameter opening 82b is formed on one side in the longitudinal direction of the holding member 81 in the opening hole 82, and the small-diameter opening 82a is formed on the other side in the longitudinal direction of the holding member 81 in the opening hole 82.
  • the opening diameter of the small diameter opening 82a is set to be larger than the diameter of the cylindrical portion of the protector 66 and smaller than the outer diameter of the contact piece 69 of the protector 66.
  • the opening diameter of the large-diameter opening portion 82 b is set to be larger than the outer diameter of the contact piece 69.
  • the large-diameter opening 82b can pass through the contact piece 69.
  • the holding member 81 is not limited to the one described above, and the opening hole 82 is only the large-diameter opening 82b in FIG. 5, and the center point of the large-diameter opening and the central axis of the protector 66 are deviated.
  • the contact piece 69 may contact a part of the edge of the opening hole 82 by not being arranged on the same axis.
  • the cylindrical portion of the protector 26 and the support portion 37 are inserted into the small diameter opening portion 82a.
  • the contact piece 69 of the protector 66 is in contact with the outer edge of the small diameter opening 82a.
  • the holding member 81 holds the protector 66 at the first position.
  • one end portion of the holding member 81 is provided with a pressing portion 83 that continues substantially vertically toward the other axial direction of the needle tube 21.
  • the pressing part 83 is formed on the large-diameter opening part 82 b side in the opening hole 82.
  • a tapered surface 83 a is formed at the corner portion on the other side in the axial direction of the needle tube 21 in the pressing portion 83.
  • the taper surface 83a is inclined in a direction away from the center of the holding member 81 as it goes from the other side in the axial direction of the needle tube 21 to one side.
  • a biasing portion 87 is disposed between the pressing portion 83 and the insertion portion 91 of the second member 64.
  • the pressing portion 83 faces the outer peripheral surface of the insertion portion 91 of the second member 64.
  • an urging portion 87 is disposed between a surface of the pressing portion 83 facing the insertion portion 91 and the outer peripheral surface of the insertion portion 91.
  • the urging portion 87 is constituted by, for example, a compression coil spring.
  • the urging portion 87 urges the holding member 81 in a direction in which the pressing portion 83 is separated from the insertion portion 91 along a direction orthogonal to the axial direction of the needle tube 21.
  • the urging portion may be an elastic member that is elastically deformed when a predetermined pressing force is applied.
  • various other spring members such as a leaf spring, sponge, gel, and rubber member can be applied.
  • the operation plate 88 is formed in a substantially flat plate shape.
  • the operation plate 88 is arranged on the other side of the holding tube 81 in the axial direction of the needle tube 21.
  • An operation hole 89 is formed in the operation plate 88.
  • An insertion portion 91 is inserted into the operation hole 89.
  • the operation plate 88 is supported by the insertion portion 91 so as to be movable in the axial direction of the needle tube 21, and faces the pressing member 20 of the pusher member 4.
  • an operation-side tapered surface 89 a is formed at the end of the operation hole 89 on the pressing portion 83 side of the holding member 81.
  • the operation-side tapered surface 89a is inclined in a direction away from the center of the operation hole 89 as it goes from the other side in the axial direction of the needle tube 21 to one side.
  • the operation-side tapered surface 89a abuts on the tapered surface 83a of the pressing portion 83.
  • FIG. 6 is a cross-sectional view showing a state of the injection needle assembly 6 after puncturing.
  • the cylindrical portion of the protector 66 passes through the small diameter opening 82a of the holding member 81, and the contact piece 69 is in contact with the outer edge of the small diameter opening 82a. Therefore, the protector 66 is held by the holding member 81 at the first position where the needle tube 21 of the needle tube 21 is protruded from the distal end surface 66a.
  • the pressing member 20 presses the operation plate 88.
  • the operation plate 88 slides on the outer peripheral surface of the insertion portion 91 and moves toward one side in the axial direction of the needle tube 21.
  • the operation plate 88 moves toward one side in the axial direction of the needle tube 21, the pressing portion 83 is pressed in a direction approaching the outer peripheral surface of the insertion portion 91 by the operation side tapered surface 89 a of the operation hole 89. .
  • the holding member 81 moves from one side to the other side in the direction orthogonal to the axial direction of the needle tube 21 against the biasing force of the biasing portion 87. That is, the operation plate 88 and the pressing portion 83 constitute a release operation portion.
  • the contact piece 69 of the protector 66 faces the large-diameter opening 82b of the opening hole 82.
  • the opening diameter of the large-diameter opening portion 82 b is set to be larger than the outer diameter of the contact piece 69.
  • the protector 66 is urged toward the needle tip 21a side of the needle tube 21, that is, from the first position to the second position by the restoring force (biasing force) of the urging member 67. As a result, the protector 66 covers the periphery of the needle tip 21 a of the needle tube 21, and the needle tube 21 is accommodated in the protector 66.
  • the present invention is not limited to this, and the male screw portion is provided in the discharge portion, and the second member of the injection needle assembly 2 is provided.
  • a female screw portion may be provided in the 24 cylindrical holes and screwed together.
  • the holding member 42 may be operated by the user's hand or the pressing member 83 of the holding member 81 may be pressed without providing the pressing member.
  • elasticity is applied to the contact piece of the protector, the contact piece is detachably engaged with the first opening of the base part and the second opening of the insertion part, and the protector is held by the base part and the insertion part.
  • the urging member is disposed between the bottom surface of the housing recess and the rear end portion in the axial direction of the protector. Is not to be done.
  • the urging member may be arranged closer to the needle tip 21 a side of the needle tube 21 than the holding and maintaining portion 42 or the holding member 81. Thereby, it can be urged that the urging member interferes with the holding portion and the holding release portion, and the movement operation of the protector can be performed smoothly.
  • two holding members 81 according to the second embodiment are prepared, and are superposed so that the center point of the opening hole 82 of the two holding members 81 is not coaxial.
  • the contact piece 69 is in contact with part of the edge of both the opening holes 82. Then, the contact of the contact piece 69 may be released by moving the two holding members 81 in the opposite directions to increase the opening formed by the two opening holes.

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

L'invention concerne un ensemble aiguille d'injection et un dispositif d'injection de médicament qui peuvent éviter une piqûre accidentelle d'un utilisateur par la pointe d'un tube d'aiguille après l'administration de médicaments et pendant la mise au rebut. Ledit ensemble aiguille d'injection (2) est pourvu de : un tube d'aiguille (21) ; une embase d'aiguille (22) destinée à maintenir le tube d'aiguille (21) ; un dispositif de protection (26) pourvu d'une pièce de contact (29) ; un élément d'actionnement (27) ; un élément de retenue (43) ; et des mécanismes de retenue et de libération (41, 42). Le dispositif de protection (26) peut se déplacer entre une première position dans laquelle la pointe (21a) du tube d'aiguille (21) est découverte et une seconde position dans laquelle la pointe (21a) du tube d'aiguille (21) est recouverte. L'élément d'actionnement (27) déplace le dispositif de protection (26) à partir de la première position dans la direction de la seconde position, le long de la direction axiale du tube d'aiguille (21). Lorsque le dispositif de protection (26) est déplacé dans la seconde position, l'élément de retenue (43) vient en contact avec la pièce de contact (29). En outre, les mécanismes de retenue et de libération (41, 42) maintiennent amovible le dispositif de protection (26) dans la première position.
PCT/JP2016/056001 2015-03-30 2016-02-29 Ensemble aiguille d'injection et dispositif d'injection de médicament WO2016158145A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2017509414A JP6665165B2 (ja) 2015-03-30 2016-02-29 注射針組立体および薬剤注射装置

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JP2015-068630 2015-03-30
JP2015068630 2015-03-30

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WO2016158145A1 true WO2016158145A1 (fr) 2016-10-06

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WO (1) WO2016158145A1 (fr)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0810324A (ja) * 1990-07-19 1996-01-16 Nardino Righi 使い捨て可能な安全注射器
JPH11319090A (ja) * 1998-04-17 1999-11-24 Becton Dickinson & Co 医療装置及びその遮蔽体装置
JP2002500934A (ja) * 1998-01-20 2002-01-15 セルジョ・レステッリ 使い捨て型の安全注射器
JP2003532500A (ja) * 2000-05-05 2003-11-05 セイフティ・シリンジーズ・インコーポレイテッド 注射器用の自動安全針受け
JP2010172618A (ja) * 2009-01-30 2010-08-12 Arte Corp 容器兼用注射器

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0810324A (ja) * 1990-07-19 1996-01-16 Nardino Righi 使い捨て可能な安全注射器
JP2002500934A (ja) * 1998-01-20 2002-01-15 セルジョ・レステッリ 使い捨て型の安全注射器
JPH11319090A (ja) * 1998-04-17 1999-11-24 Becton Dickinson & Co 医療装置及びその遮蔽体装置
JP2003532500A (ja) * 2000-05-05 2003-11-05 セイフティ・シリンジーズ・インコーポレイテッド 注射器用の自動安全針受け
JP2010172618A (ja) * 2009-01-30 2010-08-12 Arte Corp 容器兼用注射器

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JP6665165B2 (ja) 2020-03-13
JPWO2016158145A1 (ja) 2018-01-25

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