WO2016114504A1 - 휴대용 플라즈마 피부개선 장치 - Google Patents

휴대용 플라즈마 피부개선 장치 Download PDF

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Publication number
WO2016114504A1
WO2016114504A1 PCT/KR2015/013840 KR2015013840W WO2016114504A1 WO 2016114504 A1 WO2016114504 A1 WO 2016114504A1 KR 2015013840 W KR2015013840 W KR 2015013840W WO 2016114504 A1 WO2016114504 A1 WO 2016114504A1
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WIPO (PCT)
Prior art keywords
plasma
high voltage
skin improvement
improvement device
portable plasma
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PCT/KR2015/013840
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English (en)
French (fr)
Korean (ko)
Inventor
김성훈
서상윤
김기민
엄광현
홍인표
이영준
Original Assignee
(주)아이카이스트홀딩스
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Priority to CN201580072748.5A priority Critical patent/CN107206248B/zh
Priority to JP2017535698A priority patent/JP6625648B2/ja
Publication of WO2016114504A1 publication Critical patent/WO2016114504A1/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/0404—Electrodes for external use
    • A61N1/0408—Use-related aspects
    • A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/08—Arrangements or circuits for monitoring, protecting, controlling or indicating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/44—Applying ionised fluids

Definitions

  • the present invention relates to a dielectric barrier discharge device, and more particularly, to a portable plasma skin improvement device for generating a plasma through dielectric barrier discharge at atmospheric pressure to improve skin condition.
  • the lowest energy state of matter is solid.
  • the solid receives energy and gradually becomes a liquid, which is then transferred to a gas.
  • a plasma composed of electrons, ions, neutral atoms, and molecules may be formed by ionization and recombination of electrons and ions.
  • Plasma has various criteria such as plasma density, electron temperature, degree of thermal equilibrium between species, generation method, and application field, but it is the most basic to classify it by density and electron temperature.
  • the plasma can be classified by thermal equilibrium, and divided into local thermal equilibrium (LTE) and non-LTE, and the term local thermal equilibrium indicates that the temperature of all of the plasma particles is It means the same thermodynamic state in the local domain.
  • LTE local thermal equilibrium
  • non-LTE non-LTE
  • Plasma for research and manufacturing processes is usually either LTE or non-LTE, with the former generally referred to as thermal plasma and the latter as cold plasma.
  • low-temperature plasma is used, and it belongs to atmospheric pressure plasma among low-temperature plasmas.
  • Atmospheric pressure plasma is mainly used in the surface modification and coating of materials, environmental purification, etc. Recently, the atmospheric plasma jet research is actively progressed as applied to the fields of biological applications and biomedical.
  • the electrode structure of the plasma jet is mostly a needle-shaped needle electrode structure, and various construction methods have been studied according to a power supply device, and mainly an inert gas is injected from the outside, and a high voltage is applied to the needle electrode structure to generate plasma.
  • a plasma barrier apparatus of a dielectric barrier discharge (DBD) system in which a small configuration is provided at the center of a small circular parallel flat plate is also introduced.
  • Low frequency discharge power supplies of tens to hundreds of kHz include a DC pulse power supply and an AC power supply.
  • the MHz to GHz range of high frequency discharge includes radio frequency (RF) and microwave (MW), and power consumption of each power supply varies depending on the application.
  • the power consumption of plasma jets used in biomedical applications is mostly 100W or less.
  • Plasma jets are commonly used for sterilization and sterilization purposes.
  • the use of plasma containing oxygen radicals has been studied to whiten teeth, destroy pathogens, and coagulate blood.
  • Major issues in the use of such biomedical fields are miniaturization of devices, ease of control, and safety of the human body.
  • the high voltage electrode In order to directly apply to cells or human body of the living body, it is important to secure stability against electric shock in the plasma field. Therefore, to ensure stability, the high voltage electrode should not be in direct contact with the sample and the human body.
  • the driving voltage applied to the electrode must be lowered and the plasma current amount must be controlled to a small value of 1 to 2 mA so that there is no electric shock to the living body.
  • the minimum current that the human body can detect is about 1 mA for an adult male at 60 Hz commercial frequency AC, and the sensing current increases with increasing frequency.
  • the painful current is 7 to 8 mA, and higher currents are not only electrical, but also thermally hazardous.
  • a portable beauty device using plasma uses a light and thin carbonized plasma technology to eradicate bacteria adhered to the face or skin. It is interposed, the plasma skin regeneration device (Korean Patent No. 10-126232) has a technology that can be used to treat the skin by generating a glow plasma.
  • the conventional portable beauty device and plasma skin regeneration device using plasma require gas such as nitrogen, argon, helium, etc. to generate the plasma, thereby limiting the working time and working environment and the hassle of filling or replacing the gas during the operation. There is this.
  • Patent Document 1 Republic of Korea Utility Model Registration No. 20-0454538
  • Patent Document 2 Korean Patent Publication No. 10-1262632
  • the portable plasma skin improvement device of the present invention has a purpose to generate plasma suitable for skin improvement while being portable without using gas separately from the conventional method of using gas for plasma generation.
  • the present invention generates a low-power, low-temperature plasma in a large area through an electrode surrounded by a dielectric to prevent skin damage while improving skin whitening, skin elasticity or to improve skin problems such as acne, skin problems, wrinkles, etc.
  • a dielectric to prevent skin damage while improving skin whitening, skin elasticity or to improve skin problems such as acne, skin problems, wrinkles, etc.
  • an object of the present invention is to allow replacement of an electrode in which plasma is generated directly, so that even if the electrode is damaged due to prolonged use, it does not interfere with the use of the device.
  • the present invention is a rechargeable battery that receives an available voltage from the outside;
  • a high voltage supply module for outputting DC power supplied from the battery with alternating current power of 10 kHz to 100 kHz and 1 kV to 7 kV;
  • a plasma generation module comprising a panel-shaped electrode and a dielectric surrounding the electrode to receive the output of the high voltage supply module to generate a dielectric barrier discharge.
  • the present invention the front and rear cover for receiving the battery, the high voltage supply module and the plasma generating module therein; And a head detachably coupled to the front cover, wherein the plasma generation module is disposed on the head so that a surface thereof is exposed to the outside and extends into the front cover through the head while being connected to the electrode. And a tension terminal inside the front cover, the tension terminal being connected to the high voltage supply module and contacting the conductive pin with its own elasticity.
  • the head is provided with a protrusion for forming a predetermined space between the surface of the plasma generation module and the skin to facilitate the discharge of the dielectric barrier in the air, while the protrusion is supported so that the plasma generation module does not escape to the outside Characterized in that.
  • the present invention is characterized in that the rechargeable battery is a built-in or detachable, further comprising a power management module for providing a charging terminal for accommodating the available voltage of the rechargeable battery and to check the remaining capacity of the battery.
  • the present invention further includes a grounding portion connected to the power management module to be electrically grounded and partially exposed to the outside of the front and rear covers, wherein the grounding portion is entirely coated with metal and the portion exposed to the outside is coated with non-conductive material. It is characterized in that the injection further made.
  • the metal coating of the ground portion has a resistance of 10 ⁇ / cm 2 or less, and the non-conductive coating is made to have a thickness of 20 ⁇ m to 50 ⁇ m.
  • the high voltage supply module may include a DC input unit receiving power from the battery; A DC voltage controller for controlling ON / OFF of the voltage transmitted through the DC input unit; AC high voltage conversion unit for outputting the output voltage of the DC voltage control unit to a low frequency high voltage AC power, characterized in that for outputting a pulse having an ON / OFF period of 0.1 Hz to 1 kHz.
  • the dielectric is composed of a lower plate that is opposed to the upper plate exposed to the outside, the upper plate is characterized in that the thickness of less than 1 mm and the lower plate is thicker than the upper plate.
  • the present invention is characterized in that it further comprises a power control module for controlling the output and the ON / OFF of the high voltage supply module.
  • Portable plasma skin improvement device unlike the conventional method using the gas to increase the efficiency of the plasma through the high-voltage supply module and the panel-shaped plasma generation module to safe plasma in the air over a large area in a large area As it can be generated, a compact and portable structure can be used to improve skin condition by anyone.
  • the skin improvement device can generate a low-power low-temperature plasma in a relatively large area, the skin improvement effect by the plasma as described in various papers or journals, for example, bacteria, organic matter, foreign matter, etc. in the skin or pores It removes and stimulates fibroblasts of the dermal layer to promote collagen and elastin formation, thereby showing skin regeneration and elasticity.
  • the present invention can be replaced by a plasma generation module that generates a plasma directly to the skin can be used semi-permanently through a simple replacement process even if the damage occurs due to repeated use or poor management.
  • FIG. 1 is a block diagram showing the operation principle of a portable plasma skin improvement device according to the present invention.
  • FIG. 2 to 4 is a view showing the appearance of a portable plasma skin improvement device according to the present invention.
  • FIG 5 and 6 are views showing the internal structure of the portable plasma skin improvement device according to the present invention.
  • FIG. 7 is a cross-sectional view showing a plasma generation module of the portable plasma skin improvement device according to the present invention.
  • FIG. 8 is a view showing an example of a pulse output from the high voltage supply module of the portable plasma skin improvement device according to the present invention.
  • FIG. 1 is a block diagram showing the operation principle of the portable plasma skin improvement device of the present invention.
  • Portable plasma skin improvement device is basically a rechargeable battery 10, a high voltage supply module 20 for outputting the power supplied from the battery 10 as a low frequency high voltage AC power, high voltage supply module 20 Including the plasma generation module 30 to receive the output of the dielectric barrier discharge (Dielectric barrier discharge) to generate a plasma to enable skin improvement to the plasma generation module 30 side.
  • a high voltage supply module 20 for outputting the power supplied from the battery 10 as a low frequency high voltage AC power
  • high voltage supply module 20 Including the plasma generation module 30 to receive the output of the dielectric barrier discharge (Dielectric barrier discharge) to generate a plasma to enable skin improvement to the plasma generation module 30 side.
  • Dielectric barrier discharge dielectric barrier discharge
  • the rechargeable battery 10 is installed in a built-in type as shown in FIG. 5 or installed in a detachable form as applied to a conventional mobile phone, a portable multimedia player (PMP), etc. to receive an available voltage from the outside, for example, 110V or The available voltage can be supplied through an adapter that outputs 220V commercial voltage or a USB cable connected to a computer or a laptop.
  • PMP portable multimedia player
  • the high voltage supply module 20 outputs the DC power supplied from the battery 10 as a low frequency high voltage AC power.
  • the high voltage supply module 20 outputs a low frequency of 10 kHz to 100 kHz and a high voltage of 1 kV to 7 kV.
  • it functions to output a pulse (see Fig. 8) having an ON / OFF period of 0.1 Hz to 1 kHz.
  • the reason for limiting the low frequency high voltage range and the output voltage OFF cycle of the high voltage supply module 20 is to prevent excessive temperature rise of the plasma generation module 30 and to suppress the amount of ozone generated. More specifically, the low frequency high voltage mentioned above When the plasma generation module 30 is continuously delivered, the temperature can reach a temperature enough to damage the skin for a short period of time, and the user may feel a sense of rejection due to the unique vivid odor due to the ozone generated incidentally during the plasma discharge. Therefore, when the low frequency high voltage as described above with a time difference of 0.1 Hz to 1 kHz is supplied, the temperature of the plasma generating module 30 does not exceed a maximum of 40 ° C, and only a small amount of ozone is generated.
  • the high voltage supply module 20 is a DC voltage for controlling the ON / OFF of the voltage transmitted through the DC input unit 21 and the DC input unit 21, the power supplied from the battery 10 as shown in FIG.
  • the control unit 22 and the AC high voltage conversion unit 23 for outputting the output voltage of the DC voltage control unit 22 as a low frequency high voltage AC power, wherein the DC voltage control unit 22 of the high voltage supply module 20
  • the pulses function to have an ON / OFF period of 0.1 Hz to 1 kHz.
  • the plasma generation module 30 is composed of an electrode 31 which may have various panel shapes such as a circle, a square, an oval, and a dielectric 32 surrounding the electrode 31 to receive the output of the high voltage supply module 20.
  • the dielectric 32 includes an upper plate 32-1 that is exposed to the outside of the device and discharges plasma to the skin, and a lower plate 32-2 disposed opposite thereto. do.
  • the electrode 31 is preferably made of a material such as gold, silver, copper, molybdenum manganese which is a conductor.
  • the upper plate 32-1 prevents arc discharge that may damage the skin from the plasma discharge form, and the thickness of the lower plate 32-2 is lower than 1 mm for effective plasma discharge for skin improvement. ) Has a thickness thicker than that of the upper plate 32-1, so that the plasma discharge phenomenon does not occur on the lower plate 32-2 side.
  • the upper and lower plates 32-1 and 32-2 are preferably made of ceramic, silicon, quartz, or the like.
  • the portable plasma skin improvement device is detachable from the front and rear covers 40 and 50 and the front cover 40 to accommodate the battery 10, the high voltage supply module 20 and the plasma generating module 20 therein.
  • a head 60 that is possibly coupled will be included as in FIGS. 2 and 3.
  • the front and rear covers 40 and 50 may be applied to any design as long as the structure enables the installation of various components of the present invention to a size that can be easily moved by a user as a structure that is detachably coupled to each other.
  • the head 60 has a structure in which the plasma generating module 30 is inserted and detachably spirally coupled to the front cover 40 while providing a space for exposing its surface, that is, the upper plate 32-1, to the outside.
  • the plasma generation module 30 further has a conductive pin 33 extending into the front cover 40 through the head 60 while being connected to the electrode 31, and inside the front cover 40.
  • the head 60 is provided with a protrusion 61 for forming a predetermined space between the surface of the plasma generating module 30, that is, the top plate 32-1, and the skin to facilitate dielectric barrier discharge in the air.
  • the height of the preferred protrusion 61 is 1 mm to 1.3 mm so that plasma is generated in the space between the skin and the upper plate 32-1.
  • some of the protrusions 61 of the head 60 have a shape supporting the edge of the upper plate 32-1 so that the plasma generating module 30 installed in the head 60 is not separated outward.
  • the portable plasma skin improvement device of the present invention provides a charging terminal 71 for accommodating the available voltage of the rechargeable battery 10 and enables the naked eye to check the remaining amount of the battery 10 through LED, LCD, etc. It further includes a power management module (70).
  • the present invention also includes a grounding portion 80 connected to the power management module 70 to be electrically grounded and partially exposed to the outside of the front and rear covers 40 and 50, wherein the grounding portion 80 is made of metal. More preferably, the part exposed to the outside in the state of being coated with a metal material such as chromium coating as a whole may be an injection material in which a non-conductive coating such as UV coating is added to reduce the overall weight of the device or arc discharge. It is effective to prevent the occurrence.
  • the projection 61 of the head 60 is in contact with the skin while the front and rear covers 40 and 50 are gripped. Plasma is generated in the space between the surface of the upper plate 32-1 and the skin, but the plasma is not generated when the user does not contact the ground portion 80.
  • the metal coating of the ground portion 80 has a resistance of 10 ⁇ / cm 2 or less, and the non-conductive coating has a thickness of 20 ⁇ m to 50 ⁇ m, and the reason is that the metal coating is 10 ⁇ . If / cm 2 is exceeded, it causes the connection failure between the grounding part 80 and the power management module 70. Also, when the non-conductive thickness is not formed in the above-mentioned form, an arc discharge occurs between the skin and the grounding part when it is thin. When thick or thick, there is a problem that the coating surface is not uniform.
  • the present invention includes a power control module 90 for controlling the output and the ON / OFF of the high voltage supply module 20 to manage the power supply from the battery 10 or the pulse mode of the high voltage supply module 20 It is possible to change within the described range, and configured to include a device such as an LED to visually enable this control operation selection.
  • This human application test was measured after stabilization in a constant temperature and humidity room (temperature: 22 ⁇ 1 °C, humidity: 45 ⁇ 5%) for 30 minutes after washing with the same face wash at Korea Institute of Dermatology.
  • the spectrophotometer (Spectrophotometer CR-2600D, Konica Minolta, Japan) and the system for demagnetization system (Dermavision Pro, OptoBioMed Co., Kangwon, Korea) were used to evaluate the skin tone (brightening) improvement of the test product.
  • the spectrophotometer measured the right cheek area of all the subjects three times consecutively by the same investigator, and used the analysis by calculating the average value.
  • the measured value of the spectrophotometer consists of three factors: L *, a *, and b *.
  • the L * value is brightness
  • the a * value is redness
  • the b * value is yellowness. Indicates.
  • L * value indicating skin brightness was used for analysis, and as the measured value increased, the skin brightness improved.
  • the anterior vision system Dermavision measured the facial area of all subjects by the same investigator in uniform lighting and in the same position for consistent imaging. In order to secure the hairline of the forehead of the test subject, the hair was fixed with a hair band, and then the front of the face was photographed while wearing the same top robe and sitting on a chair. Instrument measurements were taken before, immediately after, 3 weeks of use and 6 weeks of use of the test product.
  • PRIMOS Lite field of view 18 ⁇ 13, GFMesstechnik GmbH, Germany
  • PRIMOS Lite field of view 18 ⁇ 13, GFMesstechnik GmbH, Germany
  • the same investigator photographed the right eye wrinkle area of all subjects three times consecutively.
  • the subject's face was fixed by fixing the subject's face on a specially manufactured PRIMOS facial fixation device set to prevent reproducibility and movement during measurement.
  • the captured images were subjected to 3D Matching using PRIMOS Lite software (PRIMOS Lite version 5.6E), which is a dedicated PRIMOS software, and the matched measurement sites were used for analysis.
  • the variable roughness Rt Total roughness
  • the Rt value which is a measurement parameter value, represents the total roughness of the skin, and is a difference between the highest and lowest points of amplitudes consisting of the highest and lowest skin surfaces in the entire measurement range. As the Rt value decreases, wrinkles are improved. Instrument measurements were taken before, immediately after, 3 weeks of use and 6 weeks of use of the test product.
  • DUB-Skin Scanner (tpm taberna pro medicum, Germany), a device for imaging high resolution ultrasound, was used to evaluate the dermal density of the test product.
  • Ultrasonic gel was applied to the test site, and the probe of the DUB-Skin Scanner was perpendicular to the skin, and the same tester pressed the 3 cm area of the left eye side of all the subjects with the same pressure.
  • intensity which is a parameter representing the dermal density
  • the unit of measurement is Density, which means that the dermal density is improved as the measured value is increased.
  • the investigator has erythema, edema, scaling, itching, stinging, burning, stiffness, and tingling in the skin at the test site.
  • the results of this study were prepared by observing the presence or absence of a skin reaction and marking the grade when a skin reaction occurred.
  • a questionnaire about skin adverse reactions was conducted.
  • the portable plasma skin improvement device can improve skin tone, wrinkles, skin elasticity and the like without side effects.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Electrotherapy Devices (AREA)
  • Plasma Technology (AREA)
PCT/KR2015/013840 2015-01-12 2015-12-17 휴대용 플라즈마 피부개선 장치 WO2016114504A1 (ko)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN201580072748.5A CN107206248B (zh) 2015-01-12 2015-12-17 用于改善皮肤的便携式等离子体设备
JP2017535698A JP6625648B2 (ja) 2015-01-12 2015-12-17 携帯用プラズマ肌改善装置

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KR1020150004245A KR101577207B1 (ko) 2015-01-12 2015-01-12 휴대용 플라즈마 피부개선 장치
KR10-2015-0004245 2015-01-12

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JP (1) JP6625648B2 (zh)
KR (1) KR101577207B1 (zh)
CN (2) CN111991692A (zh)
WO (1) WO2016114504A1 (zh)

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KR20190032227A (ko) * 2017-09-18 2019-03-27 아주대학교산학협력단 액상 플라즈마를 포함하는 피부 진정용 조성물
PL428459A1 (pl) * 2018-12-31 2019-05-06 Lubelska Polt Urządzenie przenośne do plazmowania, zwłaszcza roślin
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PL428461A1 (pl) * 2018-12-31 2019-05-06 Lubelska Polt Urządzenie przenośne, zwłaszcza do stymulacji roślin
WO2019093388A1 (ja) * 2017-11-08 2019-05-16 積水化学工業株式会社 プラズマ式治療装置
JP2020505986A (ja) * 2017-01-27 2020-02-27 アピックス メディカル コーポレーション 低温プラズマ肌再生のための装置及び方法
WO2021151124A1 (en) * 2020-01-21 2021-07-29 Luong Thi Hong Lien Handheld cold plasma device
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KR101851389B1 (ko) * 2016-11-07 2018-04-23 주식회사 현대메디텍 휴대용 피부 관리를 위한 플라즈마 이온 발생기
KR102039217B1 (ko) * 2017-07-28 2019-10-31 아주대학교산학협력단 비열 대기압 플라즈마 켈로이드 치료기 및 이의 용도
KR101978057B1 (ko) * 2017-10-17 2019-05-13 광운대학교 산학협력단 이극 접지 패드를 구비한 오존 방출 없는 플라즈마 피부처리 장치
DE102018209735A1 (de) * 2018-06-15 2019-12-19 Terraplasma Gmbh Plasmaeinrichtung zur Behandlung von Körperoberflächen
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