WO2016013146A1 - Générateur d'impulsions magnétiques en continu - Google Patents

Générateur d'impulsions magnétiques en continu Download PDF

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Publication number
WO2016013146A1
WO2016013146A1 PCT/JP2015/002967 JP2015002967W WO2016013146A1 WO 2016013146 A1 WO2016013146 A1 WO 2016013146A1 JP 2015002967 W JP2015002967 W JP 2015002967W WO 2016013146 A1 WO2016013146 A1 WO 2016013146A1
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WO
WIPO (PCT)
Prior art keywords
cooling
magnetic
coil
core
pulse generator
Prior art date
Application number
PCT/JP2015/002967
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English (en)
Japanese (ja)
Inventor
高木　敏行
紳一 出江
弘恭 金高
良一 永富
阿部　利彦
森　仁
建樹 八島
Original Assignee
株式会社Ｉｆｇ
国立大学法人 東北大学
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Filing date
Publication date
Application filed by 株式会社Ｉｆｇ, 国立大学法人 東北大学 filed Critical 株式会社Ｉｆｇ
Publication of WO2016013146A1 publication Critical patent/WO2016013146A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00—Magnetotherapy

Definitions

  • the present invention is a device for enhancing the magnetic stimulation effect by using a coil having a magnetic core and a cooling mechanism during repeated magnetic stimulation of peripheral nerves or cerebral cortex motor areas to enhance the motor function of the limbs. About.
  • AMI brain machine interface
  • Transcutaneous electrical nerve stimulation TENS is widely used as an electrical method.
  • the principle is to electrically stimulate the motor nerve from the outside, and restore the motor function by moving the limbs.
  • strong electrical stimulation is required. Since this phenomenon is the same as electric shock, it causes discomfort and pain due to electric shock.
  • various studies have been conducted to improve the frequency and waveform to reduce shocks, there is an inevitable problem that pain increases significantly if electrical stimulation exceeds large muscle contraction.
  • the pain associated with electrical stimulation is sensed by the analgesia distributed near the surface of the skin. Therefore, it is possible to relieve the pain of electrical stimulation by implanting the stimulation electrode subcutaneously. However, since it is necessary to always keep the signal line out of the implanted electrode, there is a big problem of bacterial infection from a wound.
  • Magnetic stimulation is another method of electromagnetically stimulating nerves without using contact electrodes. This is a method of applying a pulse current to a coil placed near a nerve to stimulate the nerve to move a muscle with an induced current generated in the nerve.
  • This magnetic stimulation method does not require a process of attaching or embedding an electrode, and in addition, there is almost no electric shock or pain such as electric shock. For this reason, stronger stimulation is possible compared to the electrical stimulation method, and there is an advantage that large muscle contraction can be obtained. For this reason, the application of electrical stimulation to diagnosis and treatment of diseases is advanced, and is put to practical use as transcranial magnetic stimulation (TMS). In particular, the combination of rTMS which repeats magnetic stimulation and exercise therapy has a large rehabilitation effect (non-patent documents 1 and 2).
  • the muscle contractions caused by electrical and magnetic stimulation are (1) muscle contraction and single contraction, and repetitive muscle contraction in which the motion is continuous, (2) continuous muscle contraction in which the finger is flexed or the limbs move greatly. Divided into two types. As a device causing the muscle contraction repeatedly in (1), there is a high frequency electrical stimulation device for the purpose of shoulder stiffness treatment and the like. The muscle contraction that occurs with this device is a periodic oscillation of the muscle at the target site.
  • Patent Document 1 discloses a device for treating urinary incontinence as an invention utilizing the muscle contraction action by magnetic stimulation. This device performs urinary incontinence treatment by repeating the periodic contraction of the bladder sphincter by generating a pulse magnetic field of 0.01 to 3 Tesla at 1 to 100 Hz from a coil for magnetic stimulation fixed to a chair or body. It is a thing.
  • Patent Document 2 A technique for continuously bending a finger or arm with magnetic stimulation instead of simple muscle contraction as in the treatment of urinary incontinence is disclosed in Patent Document 2, and magnetic pulses are repeated at intervals of 10 milliseconds to magnetize the nerve of the arm. It has been shown that upon stimulation, the distance that the arm bends also increases with the number of pulses.
  • Patent Document 3 discloses a magnetic stimulation device that obtains a convergent magnetic field by cutting a part of an O-type core, thinning an opposing part, and winding a coil there.
  • Patent Document 4 discloses a magnetic stimulation device in which a magnetic body is disposed in a space formed inside a winding.
  • Patent Document 5 describes a technique of transcranial magnetic stimulation in which a coil is wound from a high permeability semicircle to a horseshoe-shaped magnetic core to reduce heat generation of the coil and to perform magnetic stimulation of the brain.
  • Patent Document 6 discloses a technique of using a ferromagnetic material having high permeability and saturation magnetic flux density for a magnetic material core having a similar shape to this.
  • Patent Document 7 describes a technique for reducing heat generation of a coil by bundling thin litz wires, which are the conventional means of high frequency coils, and winding the coil.
  • An object of the present invention is to commercialize a continuous magnetic pulse generator capable of generating a large number of continuous magnetic stimulations with a small temperature rise due to heat generation.
  • the continuous magnetic pulse generator A uses the gas 6 for cooling, Magnetic core 2 and A coil-shaped conductor 1 wound a plurality of times by providing a coil cooling gap 3 between each other around the magnetic core 2; A casing 4 having a coil cooling vent 5 for housing the magnetic core 2 and the coiled conductor 1; The cooling gas 6 flowing through the coil cooling gap 3 is supplied to the casing 4 or a cooling mechanism 7 for discharging the same from the casing 4.
  • a second aspect of the present invention is characterized in that, in the continuous magnetic pulse generator A according to the first aspect, a core cooling gap 8 is provided between the magnetic core 2 and the casing 4.
  • the third aspect of the present invention is characterized in that in the continuous magnetic pulse generator A according to the second aspect, the casing 4 is provided with a core cooling vent hole 9 communicating with the core cooling gap 8.
  • the continuous magnetic pulse generator A uses the liquid 10 for cooling, Magnetic core 2 and A coil-shaped conductor 1 wound a plurality of times by providing a coil cooling gap 3 between each other around the magnetic core 2;
  • a fifth aspect of the present invention is the continuous magnetic pulse generator A according to the fourth aspect, wherein the cooling pipe 11 is further wound around the magnetic core 2.
  • a sixth aspect is characterized in that, in the continuous magnetic pulse generator A according to the fourth or fifth aspect, a core cooling gap 8 is provided between the magnetic core 2 and the casing 4.
  • a seventh aspect is characterized in that, in the continuous magnetic pulse generator A according to the second or eighth aspect, a heat insulating material 12 is provided in the core cooling gap 8.
  • the eighth aspect is characterized in that in the continuous magnetic pulse generator A according to any one of the first to seventh aspects, the heat insulating material 12 is provided in the core cooling gap 8.
  • a ninth aspect of the present invention relates to the continuous magnetic pulse generator A according to any one of the first to eighth aspects, wherein the magnetic core 2 is T-shaped, and the legs 2a of the T-shaped magnetic core 2 are coiled. It is characterized in that it is inserted in the space of the central portion of the wound conductor 1.
  • the coiled conductor 1 having the coil cooling gap 3 between each other is wound around the magnetic core 2 a plurality of times, and the coil cooling gap Joule generated in the conductor 1 even if a large current flows continuously by flowing the gas 6 to 3 or flowing the cooling liquid 10 to the cooling pipe 11 disposed in the coil cooling gap 3
  • the heat is taken away by the cooling gas 6 or the cooling liquid 10 so that the temperature of the conductor 1 can be kept at a suitable temperature.
  • the temperature rise of the magnetic core 2 can be suppressed. Furthermore, if the core cooling vent hole 9 communicating with the core cooling gap 8 is provided in the casing 4, the gas 6 flows through the core cooling vent hole 9 through the core cooling vent hole 9, and the magnetic core Cooling of 2 can be done simultaneously. This point is the same even when the cooling pipe 11 is further wound around the magnetic core 2. In other words, it is possible to suppress the temperature at which thermal damage such as burn does not occur even if the portion where the magnetic flux is generated intensively in the core storage portion of the continuous magnetic pulse generator A at the time of treatment contacts the affected area.
  • the heat insulating material 12 is provided in the core cooling gap 8, even if the temperature of the magnetic core 2 rises to a suitable temperature or higher, for example, to about 80 ° C., the heat insulating material 12 shuts off. It does not harm the patient.
  • FIG. 1 It is a perspective view of the present invention. It is a perspective view of the modification of the cooling mechanism of FIG. It is sectional drawing of FIG. It is a cross-sectional perspective view of the modification of the core of this invention. It is a cross-sectional perspective view in case the cooling mechanism of this invention is water cooling. It is a principal part cross-sectional perspective view of the further modification of the cooling mechanism of FIG.
  • the magnetic core 2 is T-shaped and mere plate-shaped, and the cooling method may be air cooling or water cooling.
  • the continuous magnetic pulse generator A is composed of a conductor 1, a magnetic core 2, a casing 4 and a cooling mechanism 7.
  • the magnetic core 2 is formed by laminating a large number of rolled silicon steel plates with a thin insulating film.
  • a rolled silicon steel plate is formed in a T shape and laminated.
  • the rolled silicon steel plate used in this example has a thickness of 0.35 mm.
  • the conductor 1 is a long copper plate wound in a coil shape, and an insulating film is formed on the surface thereof.
  • the thickness of the conductor 1 is 2 mm and the width 13 mm
  • the coil cooling gap 3 is provided so as not to contact each other, and a long copper plate is wound in a coil shape.
  • the coil cooling gap 3 is 1 mm in this embodiment.
  • the insulating film was made of urethane resin so as to prevent the heat radiation on the surface of the conductor 1 from being hindered.
  • the thickness of the insulating coating is 20 ⁇ m.
  • the conductor 1 is a long copper plate wound in a coil, but the invention is not limited to this, as long as the coil cooling gap 3 can be provided, for example, coil cooling The gap 3 may be provided and the copper wire may be coiled.
  • the casing 4 is made of resin (here, made of polyethylene) that accommodates the magnetic core 2 and the coiled conductor 1 and is formed of a main body 4a whose upper surface is open and a lid 4b which covers the opening. The upper surface opening is closed by a bolt (not shown).
  • a handle 4c is provided on the upper surface of the lid 4b as necessary.
  • a convex portion 4d which bulges downward is formed.
  • a large number of coil cooling air vents 5 are formed in the lower surface of the main body 4 a around the convex portion 4 d at positions corresponding to the coil cooling gaps 3 of the conductor 1 wound in a coil shape. Further, in the present embodiment, a large number of air holes 9 for core cooling are bored in the convex portion 4d.
  • the ventilation nozzle 7a provided on the side surface of the main body 4a or the fan 7b provided on the ventilation portion 7c of the side surface of the main body 4a shown in FIG. .
  • the aeration nozzle 7a is connected to an exhaust device (not shown) and the air in the casing 4 is sucked. (Or, the cooling air is blown into the casing 4 by the air supply device.)
  • the ventilation nozzle 7a or the fan 7b is provided on the side surface of the casing 4, but it is not necessarily limited to this position.
  • the coiled conductor 1 is accommodated in the main body 4a, and the coil cooling gap 3 of the coiled conductor 1 is aligned with the coil cooling air vent 5 of the main body 4a as described above. It arrange
  • the leg portion 2a of the T-shaped magnetic core 2 is inserted into the space of the central portion of the conductor 1 wound in a coil shape.
  • the leg portion 2a is fitted into the concave portion on the inner side of the convex portion 4d of the main body 4a, and the coiled conductor 1 is wound around the leg portion 2a in a spiral shape.
  • the lower end of the leg portion 2a is slightly protruded from the lower surface of the coiled conductor 1 (in the present embodiment, the amount of projection is 3 mm).
  • the lower end surface of the leg portion 2a is separated from the concave portion on the inner side of the convex portion 4d (this separated space portion becomes the core cooling gap 8). It is fixed by the method like etc.
  • the current supply condition at this time is a peak current of 1600 A, and a biphasic waveform with a pulse width of 0.2 ms (one pulse each for plus and minus) generates about 100 100 pulses per second I am doing it.
  • the energization condition is not limited to this, and an appropriate condition is selected for each patient.
  • the waveform of the magnetic pulse may be monophasic (plus or minus one wave).
  • the cooling mechanism 7 continues to operate (that is, exhaust or air supply by the aeration nozzle 7a and the fan 7b), cooling air flows from the coil cooling air holes 5 and heat of the coiled conductor 1 Take away. Then, the air also flows into the core cooling gap 8 between the magnetic core 2 and the casing 4 to cool the convex portion 4 d and the leg portion 2 a of the magnetic core 2.
  • cooling air may be allowed to flow through the core cooling gap 8 between the magnetic core 2 and the casing 4, but core cooling is applied to the convex portion 4 d of the casing 4 to obtain a higher cooling effect.
  • the cooling air may be taken into the core cooling gap 8 from the outside by providing a magnetic material core cooling vent hole 9 communicating with the gap 8.
  • the heat insulating material 12 may be provided in the cooling gap 8 instead of the magnetic core cooling vents 9.
  • FIG. 4 shows another embodiment of the magnetic core 2.
  • the magnetic core 2 is obtained by laminating the silicon steel plates in a square rod shape, and pressing the upper portion thereof into the through holes 13b of the cold-cooling fins 13 made of aluminum, for example. This is an example of mounting so that the shape becomes T-shaped.
  • a large number of cooling gaps 13a are formed in the vertical direction in the cold-cooling fins 13, and heat is taken away when the air passes through the cooling-cooling gaps 13a, and the temperature of the magnetic core 2 in contact with the cooling fins 13 Decreases.
  • the merit of using T-shaped is as follows. (1) If the area of the magnetic path is the same, the surface area will be large and cooling will be easy. 2) The coil can be made compact because the height direction can be suppressed. (3) A magnetic flux can not move upward, so equipment that is vulnerable to external magnetic fields such as a fan can be placed at the top of the coil.
  • the cooling pipe 11 in the case of water cooling, is provided so as to be in contact with the leg portion 2a of the magnetic core 2 or the coiled conductor 1 or both, and the cooling fluid is made to flow. Thereby, more effective cooling of the legs 2a and the conductor 1 is achieved.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Magnetic Treatment Devices (AREA)

Abstract

L'objectif de la présente invention est l'utilisation pratique d'un générateur d'impulsions magnétiques en continu dans lequel l'augmentation de température due à la chaleur est faible et qui permet des stimuli magnétiques continus multiples. Le générateur (A) d'impulsions magnétiques en continu comprend : un noyau magnétique (2) ; un conducteur en bobine (1) qui est enroulé de multiples fois autour du noyau magnétique (2), un espace (3) de refroidissement de bobine étant situé entre les spires du conducteur en bobine (1) ; un boîtier (4) doté d'un trou de ventilation (5) de refroidissement de bobine et contenant le noyau magnétique (2) et le conducteur en bobine (1) ; et un mécanisme de refroidissement (7) qui fournit un gaz de refroidissement (6) qui s'écoule à travers l'espace (3) de refroidissement de bobine vers le boîtier (4) ou qui évacue le gaz de refroidissement (6) du boîtier (4).
PCT/JP2015/002967 2014-07-25 2015-06-12 Générateur d'impulsions magnétiques en continu WO2016013146A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2014151715A JP5893689B2 (ja) 2014-07-25 2014-07-25 連続磁気パルス発生装置
JP2014-151715 2014-07-25

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WO2016013146A1 true WO2016013146A1 (fr) 2016-01-28

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020003437A1 (fr) * 2018-06-28 2020-01-02 株式会社Ｉｆｇ Dispositif de stimulation magnétique
CN113747939A (zh) * 2020-01-08 2021-12-03 株式会社Ifg 磁性刺激装置

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019024987A (ja) * 2017-07-31 2019-02-21 株式会社Ｉｆｇ 磁気刺激装置

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997022383A1 (fr) * 1995-12-18 1997-06-26 Soken Kenkyusyo Inc. Dispositif de therapie par induction magnetique
JP2001161830A (ja) * 1999-09-30 2001-06-19 Nippon Koden Corp 尿失禁治療用コイルの空冷装置
JP2002263203A (ja) * 2001-02-24 2002-09-17 Mfh Hyperthermiesysteme Gmbh 生物組織内の磁気的または磁化可能な物質あるいは固体を加熱する磁場アプリケータの磁気コイル装置
JP2003305131A (ja) * 2002-04-16 2003-10-28 Kyoichi Nakagawa 磁気治療器
JP2008154922A (ja) * 2006-12-26 2008-07-10 Admetech:Kk 磁場発生アプリケータ、及び、磁場発生装置
JP2008543416A (ja) * 2005-06-16 2008-12-04 ブレインズウェイ インコーポレイテッド 経頭蓋磁気刺激システムおよび方法
JP2013500081A (ja) * 2009-07-24 2013-01-07 エムキネティクス， インコーポレイテッド 伝導性コイルのための冷却システムおよび方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN202961526U (zh) * 2012-12-18 2013-06-05 深圳英智科技有限公司 经颅磁刺激线圈的半导体冷却装置

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997022383A1 (fr) * 1995-12-18 1997-06-26 Soken Kenkyusyo Inc. Dispositif de therapie par induction magnetique
JP2001161830A (ja) * 1999-09-30 2001-06-19 Nippon Koden Corp 尿失禁治療用コイルの空冷装置
JP2002263203A (ja) * 2001-02-24 2002-09-17 Mfh Hyperthermiesysteme Gmbh 生物組織内の磁気的または磁化可能な物質あるいは固体を加熱する磁場アプリケータの磁気コイル装置
JP2003305131A (ja) * 2002-04-16 2003-10-28 Kyoichi Nakagawa 磁気治療器
JP2008543416A (ja) * 2005-06-16 2008-12-04 ブレインズウェイ インコーポレイテッド 経頭蓋磁気刺激システムおよび方法
JP2008154922A (ja) * 2006-12-26 2008-07-10 Admetech:Kk 磁場発生アプリケータ、及び、磁場発生装置
JP2013500081A (ja) * 2009-07-24 2013-01-07 エムキネティクス， インコーポレイテッド 伝導性コイルのための冷却システムおよび方法

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020003437A1 (fr) * 2018-06-28 2020-01-02 株式会社Ｉｆｇ Dispositif de stimulation magnétique
CN112218680A (zh) * 2018-06-28 2021-01-12 株式会社Ｉｆｇ 磁刺激装置
CN113747939A (zh) * 2020-01-08 2021-12-03 株式会社Ifg 磁性刺激装置

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JP2016028640A (ja) 2016-03-03
JP5893689B2 (ja) 2016-03-23
TWI626067B (zh) 2018-06-11
TW201603857A (zh) 2016-02-01

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