WO2015186713A1 - Récipient, nutriment entéral en récipient ou aliment ou boisson en récipient, procédé pour inspecter un nutriment entéral en récipient ou un aliment ou une boisson en récipient, et procédé pour leur fabrication - Google Patents

Récipient, nutriment entéral en récipient ou aliment ou boisson en récipient, procédé pour inspecter un nutriment entéral en récipient ou un aliment ou une boisson en récipient, et procédé pour leur fabrication Download PDF

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Publication number
WO2015186713A1
WO2015186713A1 PCT/JP2015/065941 JP2015065941W WO2015186713A1 WO 2015186713 A1 WO2015186713 A1 WO 2015186713A1 JP 2015065941 W JP2015065941 W JP 2015065941W WO 2015186713 A1 WO2015186713 A1 WO 2015186713A1
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WIPO (PCT)
Prior art keywords
container
light
wavelength
transmittance
less
Prior art date
Application number
PCT/JP2015/065941
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English (en)
Japanese (ja)
Inventor
充 上高原
啓樹 比嘉
Original Assignee
株式会社明治
厚木プラスチック株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Application filed by 株式会社明治, 厚木プラスチック株式会社 filed Critical 株式会社明治
Priority to CN201580030268.2A priority Critical patent/CN106458420B/zh
Priority to JP2016525192A priority patent/JPWO2015186713A1/ja
Priority to SG11201610100QA priority patent/SG11201610100QA/en
Publication of WO2015186713A1 publication Critical patent/WO2015186713A1/fr

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N21/359—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using near infrared light
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/24—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/24—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants
    • B65D81/30—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants by excluding light or other outside radiation

Definitions

  • the present invention relates to a container for storing enteral nutrients, foods and drinks, and the like. Specifically, the present invention relates to a technique for managing the quality of enteral nutrients, foods and drinks, and the like.
  • a light-shielding container As a container for storing food and drink, enteral nutrients, medicines, cosmetics, etc., a light-shielding container is used to maintain the quality of the contents.
  • Patent Document 1 describes fermented milk in a light-shielding container provided with a means for blocking visible light having a wavelength of 400 to 550 nm in order to suppress deterioration in quality of fermented milk products. Storing the product is disclosed.
  • Patent Document 2 in order to prevent vitamins and amino acids contained in an infusion from being altered by a part of ultraviolet rays or visible light, a cover that blocks these lights is put on the container. It is disclosed.
  • An object of the present invention is to enable non-invasive and quick inspection of the quality of a containered enteral nutrient, a containered food and drink, etc. while suppressing deterioration and reduction of the nutritional components of the contents.
  • the container concerning one embodiment of the present invention which solves the above-mentioned subject is provided with the filling mouth which fills the contents, and the container which stores the contents.
  • the entire container is configured to have a transmittance of 75% or less for light having a wavelength of 520 nm or less.
  • the container has a transmittance of 75% or less for light having a wavelength of 520 nm or less, and a wavelength of 1100 to 1150 nm.
  • the entire container is configured to have a transmittance of 35% or less for light having a wavelength of 520 nm or less.
  • the transmittance for light having a wavelength of 520 nm or less is 35% or less.
  • the long wavelength light transmission region has a transmittance of 70% or more for light having wavelengths of 1100 to 1150 nm and 1400 to 1600 nm.
  • the container of the present invention is preferably covered with a packaging member having a transmissivity of 35% or less with respect to light of 520 nm or less in a portion other than the bottom surface of the container.
  • the containerized enteral nutrient or food / beverage product of the present invention comprises the container and the enteral nutrient or food / beverage product sealed in the container.
  • the long wavelength light transmission region is irradiated with inspection light having a wavelength of 1100 to 1150 nm and 1400 to 1600 nm. I do.
  • the method for producing a containered enteral nutrient or a containered food or drink according to the present invention includes a step of preparing the container, a step of storing contents in a container of the prepared container, and further sealing the filling port. And irradiating the long wavelength light transmission region with inspection light having a wavelength of 1100 to 1150 nm and 1400 to 1600 nm to inspect the quality of the contents.
  • a container includes a filling port for filling the contents and a container for containing the contents.
  • the entire container is configured to have a transmittance of 75% or less for light having a wavelength of 520 nm or less.
  • the container includes a long wavelength light transmission region having a transmittance of 75% or less for light having a wavelength of 520 nm or less and a transmittance of 30% or more for light having a wavelength of ⁇ nm that satisfies 700 ⁇ ⁇ ⁇ 2500.
  • a container includes a filling port for filling the contents and a container for containing the contents.
  • the container is configured such that a portion other than the bottom surface has a transmittance of 75% or less for light having a wavelength of 520 nm or less.
  • the container includes a long wavelength light transmission region having a transmittance of 75% or less for light having a wavelength of 520 nm or less and a transmittance of 30% or more for light having wavelengths of 1100 to 1150 nm and 1400 to 1600 nm.
  • the entire container is configured to have a transmittance of 75% or less for light having a wavelength of 520 nm or less, light having a wavelength of 520 nm or less can be prevented from entering the container. Therefore, it is suppressed or prevented that the nutrient component, flavor, etc. contained in the contents of the container deteriorate or decrease.
  • the container container of the present invention includes a long wavelength light transmission region having a transmittance of 75% or less for light having a wavelength of 520 nm or less and a transmittance of 30% or more for light having a wavelength of 1100 to 1150 nm and 1400 to 1600 nm. Therefore, inspection light having wavelengths of 1100 to 1150 nm and 1400 to 1600 nm can be made to enter from the outside to the inside of the container via the long wavelength light transmission region. In other words, the inspection light when inspecting the quality of the contents of the container is introduced into the container through the long wavelength light transmission region while suppressing the ingress of light that causes deterioration or reduction of the nutritional components of the contents. Can enter. Therefore, the contents can be inspected non-invasively and quickly without destroying or opening the container.
  • FIG.1 and FIG.2 is the side view and top view which show the external appearance of the enteral nutrient 20 with a container of this embodiment.
  • the enteral nutrient in a container is one in which the enteral nutrient 1 is hermetically filled in a container 10.
  • the container 10 includes a container that stores the enteral nutrient 1 (contents).
  • the container 10 has a substantially truncated cone shape whose upper surface is open.
  • the container 10 has, for example, a diameter near the bottom surface of 40 to 60 mm, a diameter near the top surface of 60 to 100 mm, a height of 50 to 200 mm, and a thickness of 0.8 to 2 mm.
  • the opening 10 a on the upper surface of the container 10 is a filling port for filling the container 10 with the enteral nutrient 1.
  • the container of the container 10 includes a container body 11 and a packaging member 12 that covers the surface of the container body 11.
  • the configuration of the container body 11 will be described in detail below.
  • the packaging member 12 is formed of, for example, an opaque plastic film such as polyethylene terephthalate or polystyrene, an aluminum vapor deposition film, or an aluminum film.
  • the packaging member 12 is printed with a display 12a about the contents.
  • 3 and 4 are a side cross-sectional view and a bottom view showing a state where the packaging member 12 is wound around the container body 11.
  • the packaging member 12 covers most of the side surface 11 a of the container body 11.
  • the packaging member 12 covers the outer peripheral edge of the bottom surface 11b of the container main body 11, but does not cover the central portion, and the container main body 11 is exposed.
  • the entire container 10 has a transmittance of 35% or less for light having a wavelength of 520 nm or less.
  • the portion of the bottom surface of the container 10 where the container body 11 is exposed without being covered by the packaging member 12 has a transmittance of 35% or less for light having a wavelength of 520 nm or less and a transmittance for light having a wavelength of 800 to 2200 nm. 55% or more.
  • this region is also referred to as “long wavelength light transmission region 10b”.
  • the long wavelength light transmission region 10b has a diameter of 20 to 55 mm, for example.
  • the aluminum film 13 is affixed to the opening 10a at the top of the container 10 as a lid, thereby sealing the container 10.
  • the aluminum film 13 is bonded to the edge of the opening 10a with an adhesive member, for example.
  • the aluminum film 13 blocks the transmission of light of all wavelengths. Note that it is not essential for the lid to block light of all wavelengths, and it is sufficient that the lid is made of a material having a transmittance of at least 75% for light having a wavelength of 520 nm or less. Moreover, from the viewpoint of long-term storage stability of the enteral nutrient 1 filled in the container 10, the lid is preferably made of a material having a light transmittance of 35% or less with a wavelength of 520 nm or less.
  • a cover 14 is further fitted into the opening 10 a from above the aluminum film 13.
  • the cover 14 is made of, for example, a transparent plastic. Although the cover 14 is not an essential component, a straw insertion port 14a is formed by a cross cut.
  • the container body 11 has a configuration in which a plurality of types of plastics are laminated. In FIG. 5, the cross section of the container main body 11 is expanded and shown.
  • the container body 11 has a configuration in which an inner layer 112 is laminated on the inner side of the main layer 111 and an outer layer 113 is laminated on the outer side of the container.
  • the main layer 111 has a configuration in which the oxygen barrier layer 111b is sandwiched between two colored layers 111a. Each colored layer 111a and the oxygen barrier layer 111b are bonded with an adhesive 111c.
  • the oxygen barrier layer 111b is made of, for example, an ethylene-vinyl alcohol copolymer resin (EVOH) that prevents permeation of oxygen.
  • EVOH ethylene-vinyl alcohol copolymer resin
  • An arbitrary adhesive is used as the adhesive 111c.
  • two types of polypropylene (PP) are mixed in the resin constituting the inner layer 112.
  • an antistatic agent surfactant or the like
  • ethylene-vinyl alcohol copolymer resin, masterbatch, compatibilizer, antistatic agent, adhesive and the like conventionally known ones can be used.
  • the container main body 11 is composed of a resin laminate including the orange colored layer 111a, and thus has an orange color as a whole.
  • This orange color is an orange having a density that is so difficult that the color inside the container body 11 and the density of the contents cannot be discriminated visually. Therefore, the container main body 11 can suppress the transmittance of light having a wavelength of 520 nm or less to 35% or less. Further, since the container body 11 is orange, light having a wavelength of 800 to 2200 nm can be transmitted with a transmittance of 55% or more.
  • the portion 11 b of the container body 11 that is not covered by the packaging member 12 is a region that becomes the long wavelength light transmission region 10 b of the container 10.
  • the long wavelength light transmission region 10b is a region irradiated with inspection light when the quality of the enteral nutrient 1 hermetically sealed in the container 10 is inspected. This inspection will be described later.
  • the enteral nutrient 1 filled in the container 10 may be a normal liquid food such as milk or fruit juice, or a concentrated liquid food such as a natural rich liquid food or an artificial thick liquid food.
  • the enteral nutrient 1 may be any of a component nutrient, a digested nutrient, and a semi-digested nutrient.
  • the enteral nutrient 1 may be a pharmaceutical or a food.
  • Enteral nutrient 1 consists of water, amino acids, peptides, proteins, lipids, phospholipids, fatty acids, carbohydrates (carbohydrates), oligosaccharides, dietary fiber and other major ingredients, vitamin A, carotenes, vitamin D, vitamin E, Vitamin K, vitamin B 1 , vitamin B 2 , vitamin B 6 , niacin, pantothenic acid, nicotinamide, folic acid, vitamin B 12 , vitamin P, vitamin Q, carnitine, choline, CoQ10 and other vitamins, calcium, magnesium
  • minerals such as phosphorus, sodium, potassium, iron, copper, zinc, manganese, selenium, chromium, and organic acids such as malic acid, citric acid, lactic acid, tartaric acid, and erythorbic acid.
  • enteral nutrient 1 is adjusted in the types and amounts of these components, the lipid composition, and the like. Further, enteral nutrient 1 may be added with various food additives and arbitrary foods for the purpose of coloring, flavoring, seasoning, improving physical properties (viscosity), emulsifying stability, pH adjustment and storage. .
  • the method for producing the enteral nutrient 20 in a container includes the steps of preparing the enteral nutrient 1 (steps S11 to 13), the step of preparing the container 10 (step S20), filling the container 10 with the enteral nutrient 1 and the like.
  • a process steps S31 to 33
  • a process steps S41 to S42 for inspecting the quality of the enteral nutrient 1 filled in the container 10 and the like.
  • step S11 the raw material for enteral nutrient 1 is prepared by a known method.
  • step S12 the prepared enteral nutrient 1 is sterilized, and in step S13, the enteral nutrient 1 is stored in a state where the prescribed enteral conditions are maintained.
  • step S20 the container 10 is produced.
  • the manufacturing apparatus 100 for forming the container body 11 includes resin kneading parts 121a, 121b, 121c, 122, 123 for kneading the materials of the colored layer 111a, the oxygen barrier layer 111b, the adhesive 111c, the inner layer 112, and the outer layer 113, respectively. Then, a laminating part 124 that laminates the resins kneaded there to form the resin sheet 114, a heating part 125 that heats the resin sheet 114, and a molding part 126 that molds the heated resin sheet 114 are provided.
  • each resin kneading part 121a, 121b, 121c, 122, 123 The supplied plural kinds of materials are kneaded in each resin kneading part 121a, 121b, 121c, 122, 123. As shown in FIG. 7, the resin that has been kneaded and made uniform is sent out from the discharge port and is further supplied to the stacking section 124. Then, each resin is laminated so as to form an integrated sheet in the laminated portion 124, and sent out as a resin sheet 114.
  • the resin sheet 114 is further fed into the heating unit 125 and heated. Subsequently, in the molding unit 126, the resin sheet 114 is pressed by the molds 126a and 126b, and is molded into a desired container mold to be a resin molded product 115. The molded resin molded product 115 is cooled and cut out along the shape of the edge of the opening 10a to complete the container body 11. In addition, you may reuse and include the resin end material produced when the container main body 11 is cut out in the material of the colored layer 121a as mentioned above.
  • the container 10 is formed by covering the container body 11 with the packaging member 12.
  • step S31 enteral nutrient 1 is filled in the prepared container 10.
  • step S32 the aluminum film 13 is attached to the opening 10a of the container 10 for sealing, and the cover 14 is further covered.
  • step S33 enteral nutrient 1 (contained enteral nutrient 20) sealed in container 10 is stored in storage box 30.
  • FIG. 9 is a perspective view showing a state in which the enteral nutrient 20 in a container is stored in the storage box 30.
  • FIG. 10 is the figure which looked at the storage box 30 which accommodated the enteral nutrient 20 with a container from the bottom face.
  • the storage box 30 is made of cardboard, for example.
  • the storage box 30 is provided with an inspection hole 31 on the bottom surface. Therefore, when the enteral nutrient 20 in a container is stored, as shown in FIG. 10, the long wavelength light transmission region 10 b on the bottom surface of the container 10 is exposed through the inspection hole 31.
  • step S41 the quality inspection of the enteral nutrient 1 filled in the stored enteral nutrient 20 in the container is performed.
  • light in the near infrared region is used as inspection light.
  • Absorption spectra of organic substances such as water, lipids, and proteins exist in the near infrared region, so light in the near infrared region can be used as inspection light.
  • inspection apparatus using near-infrared light as the inspection light
  • “Compovision” manufactured by Sumitomo Electric Industries, Ltd., “Infraser” manufactured by Technicon Corporation, or the like can be used.
  • These inspection apparatuses irradiate inspection light to the long wavelength light transmission region 10b of the enteral nutrient 20 in a container.
  • the irradiated inspection light enters the container 10 of the enteral nutrient 20 in the container from the long wavelength light transmission region 10 b and reaches the enteral nutrient 1.
  • a part of the inspection light reaching the enteral nutrient 1 is absorbed by the enteral nutrient 1 and the rest is reflected.
  • a part of the light reflected by the enteral nutrient 1 passes through the long wavelength light transmission region 10b again and then reaches the inspection device. Then, in the inspection apparatus, the wavelength and the amount of light that has reached are measured. The quality of the enteral nutrient 1 can be inspected by analyzing the measured wavelength and amount of light.
  • measurement is performed using light having a wavelength of 800 to 2200 nm as inspection light, but it is not essential to scan the inspection light over the entire range of 800 to 2200 nm. What is necessary is just to irradiate the light of a wavelength required for the detection of the quality of the target component to be examined at least. For example, in order to inspect the state of contamination by microorganisms in the enteral nutrient, at least light of 1100 to 1150 nm and 1400 to 1600 nm may be irradiated.
  • the resolution of these inspection apparatuses is, for example, 1 mm under the conditions of a frame rate of 300 fps (Frames per second), a visual field width of 300 mm, and a line speed of 20 m / min (“Compovision” manufactured by Sumitomo Electric Industries, Ltd.). "in the case of). That is, in this case, image processing of 300 frames is performed while the inspection object passes through the viewing width of 300 mm.
  • the long wavelength light transmission region 10b is exposed on the surface of the storage box 30 through the inspection hole 31 on the bottom surface of the storage box 30.
  • Quality inspection can be performed without removing 20 from the storage box 30.
  • the inspection apparatus can perform image processing at high speed and high resolution as described above, quality inspection can be performed quickly in a very short time.
  • the quality inspection of the containered enteral nutrient 20 can be performed in the state of being accommodated in the storage box 30, the quality inspection is performed on the total number of manufactured enteral nutrients 20 in the container. Can do.
  • the enteral nutrient 20 contained in the container determined to be defective in this quality inspection is taken out from the storage box 30 and discarded.
  • the containered enteral nutrient 20 obtained through the above steps is stored as a quality-tested enteral nutrient 20 in step S42.
  • the storage box 30 may be further accommodated in another box, or another cardboard paper may be attached to the bottom surface of the storage box 30 to close the inspection hole 31 on the bottom surface.
  • the containered enteral nutrient 20 stored in the storage box 30 is shipped at an appropriate time.
  • the enteral nutrient 20 in a container that has undergone quality inspection may be shipped immediately without being stored.
  • the deterioration of the nutrient components of the enteral nutrient 1 due to light or the like is suppressed, and the quality inspection of the enteral nutrient 1 is performed non-invasively and quickly after filling the container.
  • the long wavelength light transmission region has a light transmittance of 70% or more in the wavelength range of 1100 to 1150 nm and 1400 to 1600 nm necessary for examining the contamination state of microorganisms. It is possible to quickly detect the state of alteration of the enteral nutrient 1 such as decay or coagulation.
  • the quality inspection can be performed non-invasively and rapidly after the container is filled, the microbial contamination state is inspected for the total number of enteral nutrient-containing containers 20. Including quality inspection. Therefore, before shipping the enteral nutrient 20 contained in a container, it is possible to reliably detect the occurrence of alteration such as corrosion or coagulation, and it is possible to ship with the quality of the total number guaranteed. Hereinafter, this point will be described in detail.
  • the light absorption wavelength of the nutrient component contained in the enteral nutrient 1 has a peak that absorbs light in the visible light region and the ultraviolet region. And it is known that the nutrient component is deteriorated by the radical generated by the light irradiation or the content thereof is reduced.
  • vitamin A absorbs light with a wavelength of 325 nm.
  • Vitamin E absorbs light with a wavelength of 260-265 nm.
  • Vitamin B 6 absorbs light with a wavelength between 285 and 295 nm.
  • Vitamin B 2 (riboflavin) absorbs light with a wavelength of 520 nm.
  • Vitamin B 12 absorbs light with a wavelength of 350-360 nm.
  • Folic acid absorbs light in the ultraviolet region (255-257 nm, 281-285 nm, and 361-369 nm).
  • the enteral nutrient 1 is irradiated with light in the visible light region and the ultraviolet region, so that aroma components, flavors, pigments and the like deteriorate or decrease, and off-flavor and oxidation occur.
  • the container body 11 of the container 10 hermetically filled with the enteral nutrient 1 is formed of an orange plastic, the light transmittance for light having a wavelength of 520 nm or less is 35% or less. (See FIG. 14 described in Experiment 4 below.) Therefore, the container 10 can shield light having a wavelength of 520 nm or less, and as a result, even if the enteral nutrient 20 contained in the container is displayed as a product in the storefront and illuminated in the store, the enteral nutrient It is possible to suppress the deterioration or decrease of 1 nutritional component, flavor component, flavor, pigment, or off-flavor or oxidation.
  • the orange plastic composing the container body 11 has a transmittance of 55% or more for light with a wavelength of 800 to 2200 nm.
  • the transmittance is 70% or more (see FIG. 14 described in Experiment 4 described later). Therefore, since the inspection light in the near infrared region used in the quality inspection can enter the inside of the container 10 through the long wavelength light transmission region 10b on the bottom surface, the container 10 remains in a sealed state, The quality inspection of enteral nutrients can be performed invasively and quickly. In addition, since quality inspection of enteral nutrients can be performed non-invasively and quickly, quality inspection can be easily performed on the total number of enteral nutrients 20 in containers.
  • the long wavelength light transmission region 10 b is provided on the bottom surface of the container 10.
  • an inspection hole 31 is provided in the bottom of the storage box 30 corresponding to the container 10 stored therein. Therefore, when the container 10 is stored in the storage box 30, the long wavelength light transmission region 10 b of the container 10 is exposed on the surface of the storage box 30 even when the storage box 30 is closed. Therefore, the quality inspection of the enteral nutrient 1 can be quickly performed without destroying or opening the storage box 30. In addition, since the quality inspection of the enteral nutrient 1 can be quickly performed without destroying or opening the containered enteral nutrient 20 or the storage box 30 (non-invasive), the shipment is attempted.
  • the enteral nutrient 20 in a container can be easily inspected. By performing quality inspection on the total number of enteral nutrients 20 in a container, products that do not satisfy the standards can be surely removed before shipping the enteral nutrient 20 in a container. And as a result, the reliability of the quality of the enteral nutrient 20 in a container increases.
  • an orange translucent plastic has been described as a plastic that achieves a transmittance of 35% or less with respect to light having a wavelength of 520 nm or less.
  • the container main body 11 should just be formed with the material which has the transmittance
  • the transmittance for light having a wavelength of 520 nm or less is preferably 60% or less, more preferably 50% or less, and even more preferably 35% or less. .
  • the orange translucent plastic has been described as the plastic that realizes a transmittance of 55% or more with respect to light having a wavelength of 800 to 2200 nm.
  • the container body 11 may be formed of a material having a transmittance of 30% or more for light having wavelengths of 1100 to 1150 nm and 1400 to 1600 nm.
  • the quality of the contents can be inspected non-invasively as long as the plastic realizes a transmittance of 30% or more for light with wavelengths of 1100 to 1150 nm and 1400 to 1600 nm. It has been confirmed that there is.
  • the light transmittance with respect to light having wavelengths of 1100 to 1150 nm and 1400 to 1600 nm is preferably 50% or more, and more preferably 70% or more. preferable.
  • Examples of such a material include a red translucent plastic and a brown translucent plastic. Further, a color (for example, red) having a light transmittance of 35% or less at a wavelength of 520 nm or less and a color (for example, blue) having a light transmittance of 70% or more at wavelengths of 1100 to 1150 nm and 1400 to 1600 nm. Even in the case of plastics with a combination of colors, a transmittance of 35% or less for light having a wavelength of 520 nm or less and 70% or more for light having wavelengths of 1100 to 1150 nm and 1400 to 1600 nm can be realized.
  • an orange plastic that is lighter than the orange color described in the present embodiment for example, a plastic that is colored using a model number “SCPPM66521” manufactured by Sankyo Chemical Industry Co., Ltd. as an orange masterbatch). Even in such a case, it is possible to realize a transmittance of 75% or less for light having a wavelength of 520 nm or less and 30% or more for light having wavelengths of 1100 to 1150 nm and 1400 to 1600 nm.
  • the color of the container body appears only in the long wavelength light transmission region 10b on the bottom surface of the container 10 as the appearance of the enteral nutrient 20 in the container. This is because the side surface of the container body is covered with the light-shielding packaging member 12 and the aluminum film 13 is attached to the opening 10 a of the container 10. Therefore, it is possible to select the color of the container body without considering the preference of the person who takes the enteral nutrient 1 from the enteral nutrient 20 in the container.
  • the container body 11 is formed using a resin kneaded with an orange master batch as a method of coloring the container body 11 in orange.
  • the method is not particularly limited thereto.
  • the container body 11 may be formed by pasting an orange translucent film on the surface of a colorless and transparent plastic.
  • the entire container body 11 is described as being made of an orange translucent plastic.
  • the container 10 is not particularly limited as long as at least a part of the container 10 is the long wavelength light transmission region 10b.
  • the bottom surface of the container body 11 is an orange translucent plastic having a transmittance of 75% or less with respect to light having a wavelength of 520 nm or less and 30% or more with respect to light having wavelengths of 1100 to 1150 nm and 1400 to 1600 nm.
  • the side surface may be formed of a white opaque plastic.
  • the bottom surface of the container body 11 is an orange translucent plastic having a transmittance of 75% or less for light having a wavelength of 520 nm or less and 30% or more for light having a wavelength of 1100 to 1150 nm and 1400 to 1600 nm.
  • the side surface may be formed of a colorless and transparent plastic.
  • the side surface of the container body 11 may be covered with a light-shielding packaging member.
  • the entire container body 11 is made of the same color plastic.
  • the bottom surface of the container 10 is the long-wavelength light transmission region 10b, but is not particularly limited thereto.
  • a part of the side surface of the container 10 may constitute a long wavelength light transmission region.
  • the long-wavelength light transmission region 10b is preferably provided on the bottom surface of the container 10 from the viewpoint that the quality inspection of the enteral nutrient 1 can be performed.
  • the side surface of the container main body 11 is described as being covered with the packaging member 12, but the container main body 11 may be exposed without being covered with the packaging member 12. Even in this case, if the transmittance of the entire container main body 11 with respect to light having a wavelength of 520 nm or less is 75% or less, the light having a wavelength of 520 nm or less can be prevented from entering the container 10. In this case, the entire container provided in the container 10 becomes a long wavelength light transmission region.
  • the container body 11 is exposed on the surface in the long-wavelength light transmission region 10b.
  • the transmittance of light with wavelengths of 1100 to 1150 nm and 1400 to 1600 nm can be maintained at 30% or more.
  • the container body 11 may be covered with a colorless transparent film or the like.
  • the container 10 is sealed by attaching the aluminum film 13 as a lid to the opening 10a of the container 10, but the present invention is not particularly limited thereto.
  • the opening may be sealed with a plastic lid instead of an aluminum film.
  • you may close the opening part of the container 10 by methods, such as hot press, without providing another member as a cover body.
  • the container body 11 is covered with the packaging member 12 in the container preparation process of step S20 during the manufacturing process of the enteral nutrient 20 in a container, but the present invention is not particularly limited thereto.
  • the container body 11 may be covered with the packaging member 12 after the container body 11 is prepared and the enteral nutrient 1 is filled.
  • the transmittance of the container body with respect to light having a wavelength of 520 nm is not 75% or less, for example, prior to filling with enteral nutrient 1, the transmittance of light in a wavelength region of 520 nm or less is 75% or less.
  • the container body It is necessary to cover the container body with the wrapping member and to prevent the light in the wavelength region of 520 nm or less from entering the container body. Further, when the transmittance of the container main body with respect to light having a wavelength of 520 nm is not 35% or less, the light transmittance in the wavelength region of 520 nm or less is 35% or less prior to filling with enteral nutrient 1. It is preferable to cover the container body with a member. Thereby, the long-term preservation property of enteral nutrient 1 improves.
  • the container body 11 has been described as being formed of a material mainly made of polypropylene, the container body 11 is made of a material mainly made of polystyrene (PS), polyvinyl chloride (PVC), polyethylene terephthalate (PET), or the like. May be formed.
  • PS polystyrene
  • PVC polyvinyl chloride
  • PET polyethylene terephthalate
  • the container 10 has a substantially truncated cone shape
  • the present invention is not particularly limited thereto.
  • the container may have a shape such as a polygonal column, a polygonal pyramid, a cylinder, or a sphere.
  • the container may be a bag-like thing which does not take a fixed shape.
  • the container-containing enteral nutrient 20 in which the enteral nutrient 1 is hermetically filled in the container 10 has been described, but the present invention is not particularly limited thereto.
  • food and drink in a container in which the container 10 is filled with the food and drink such as yogurt, fruit juice drink, milk drink, soft drink, taste drink, jelly-like food, liquid seasoning, liquid sauce, soup, paste-like food, etc.
  • the container of the present invention can be suitably used even for powdered foods such as
  • the state of microbial contamination of the enteral nutrient 1 (corrosion state of the enteral nutrient 1) is inspected, and the container 10 is 1100 to 1150 nm and 1400.
  • the transmittance for light of ⁇ 1600 nm is 30% or more
  • the wavelength required for the inspection In the region it is sufficient that the light transmittance is 30% or more.
  • the transmittance in the wavelength ranges of 1150 to 1225 nm, 1365 to 1445 nm, 1670 to 1750 nm, and 2250 to 2415 nm should be 30% or more. That's fine.
  • the transmittance in the wavelength region of 1875 to 1930 nm may be 30% or more.
  • the transmittance in the wavelength range of 1880 to 1905 nm may be 30% or more.
  • the transmittance in the wavelength regions of 740 to 770 nm, 900 to 950 nm, 1400 to 1445 nm, 1850 to 1910 nm, and 2175 to 2200 nm may be 30% or more.
  • the transmittance in the wavelength regions of 1759 nm, 2310 nm, and 2230 nm may be 30% or more.
  • the transmittance at a wavelength of 2180 nm may be 30% or more.
  • the transmittance in the wavelength region of 2310 nm may be 30% or more.
  • the transmittance in the wavelength region of 2100 nm and 2180 nm may be 30% or more.
  • the transmittance in the wavelength ranges of 1198 nm, 1706 nm, and 2282 nm may be 30% or more.
  • the transmittance in the wavelength regions of 1324 nm, 1656 nm, 1756 nm, and 1820 nm may be 30% or more.
  • the transmittance in the wavelength region near 1900 nm may be 30% or more.
  • the transmittance in the wavelength regions of 1680 nm, 1690 nm, 1730 nm, and 2208 nm may be 30% or more.
  • the transmittance in the wavelength region of 2266 nm may be 30% or more.
  • the transmittance in the wavelength range of 1420 nm, 1784 nm, and 2226 nm may be 30% or more.
  • the transmittance in the wavelength ranges of 1254 nm, 1660 nm, 2178 nm, and 2306 nm may be 30% or more.
  • the transmittance in the wavelength range of 1100 to 2200 nm may be 30% or more.
  • the transmittance in the wavelength range of 800 to 900 nm and 1710 to 1770 nm may be 30% or more. Note that light having a wavelength of 1710 to 1770 nm used as inspection light for detecting hair corresponds to a spectrum of a thiol group (SH group) in cystine.
  • SH group thiol group
  • the wavelength of the inspection light used for the microorganism inspection is in the range of 1100 to 1150 nm and 1400 to 1600 nm, but it may be shifted from the range of 1100 to 1150 nm and 1400 to 1600 nm depending on the inspection conditions. In some cases, microbiological tests can be performed. Therefore, it is not an essential configuration that the long wavelength light transmission region 10b of the container of the present invention is formed of a material having a transmittance of 30% or more for light having wavelengths of 1100 to 1150 nm and 1400 to 1600 nm.
  • the long-wavelength light transmission region 10b of the container of the present invention only needs to have a transmittance of 30% or more for light having a wavelength required depending on the inspection conditions. That is, among the light in the near-infrared region (700 nm or more and 2500 nm or less), the transmittance for light having a wavelength of ⁇ nm (700 ⁇ ⁇ ⁇ 2500) required according to the inspection condition is 30 in the nutritional component inspection. % Or more.
  • the transmittance of light having a wavelength of 520 nm or less is 75% or less in the entire container 10, but this is not an essential configuration in the present invention.
  • the container 10 of the present invention may be configured so that the portion other than the bottom surface of the container body 11 has a transmittance of 75% or less with respect to light having a wavelength of 520 nm or less. You may be comprised with the transparent material.
  • the transmittance of the bottom surface of the container with respect to light having a wavelength of 520 nm or less is greater than 75%, light having a wavelength of 520 nm or less hardly enters the inside of the container. Therefore, even if the bottom surface of the container is made of a material having a transmittance of more than 75% for light having a wavelength of 520 nm or less, the nutritional components and flavors of the enteral nutrient 1 are deteriorated or decreased by the light having a wavelength of 520 nm or less. It is suppressed or prevented.
  • FIG. 11 is a graph showing the measurement results of Experiment 1.
  • the red and orange plastic sheets have a transmittance of 5% or less for light having a wavelength of 520 nm or less (ultraviolet light and visible light), and light having a wavelength of 700 nm or more (near wavelength). It was found that the transmittance of (infrared light) was 92% or more.
  • Example 2 The following experiment 2 was performed for the purpose of evaluating the light shielding properties of the orange, white, and transparent containers.
  • vitamin B 2 (VB 2 ) is selected as a representative light-sensitive nutrient component, and the content of vitamin B2 in the sample before and after the start of light irradiation is measured, thereby shielding the light of each color container. Sex was evaluated.
  • each of the orange, white, and transparent containers is filled with a commercially available liquid food (trade name: Meiji May Balance Mini (registered trademark), manufactured by Meiji Co., Ltd.), and Example 1, Comparative Example 1, and Comparative Example 2, respectively. It was. Then, the amount of VB 2 contained in liquid food of Example 1 and Comparative Examples 1 and 2 (hereinafter, also referred to as VB 2 content.) was measured and the initial value of VB 2 content. The VB 2 content is measured at the high speed specified in the notice of “Analytical Methods for Nutritional Components in Nutrition Labeling Standards” (April 26, 1999) It carried out according to the liquid chromatograph method.
  • the container was stored at an ambient temperature of 25 ° C. while being irradiated with light at an illuminance of 15000 lux.
  • the VB 2 content was measured in the same manner as at the start of storage for samples after 1 week, 2 weeks, 3 weeks and 4 weeks had elapsed since the start of light irradiation.
  • the VB 2 content in the sample after light irradiation was divided by the initial value of the VB 2 content before light irradiation, and the retention rate of VB 2 after light irradiation with respect to the initial value was calculated.
  • the retention rate was 30% or more, it was evaluated that “the nutritional component (VB 2 ) is well retained”, that is, “the container has sufficient light shielding properties”.
  • Example 1 in Experiment 2 The same sample as Example 1 in Experiment 2 was produced. And the amount of VA, VE, VK, VB 6 , VB 12 and folic acid contained in the liquid food (hereinafter also referred to as VA content, VE content, VK content, VB 6 content, VB 12 content, and folic acid content, respectively) .) was measured and used as the initial value of the content of each nutritional component.
  • VA content, VE content, VK content, VB 6 content, VB 12 content, and folic acid content was measured and used as the initial value of the content of each nutritional component.
  • the measurement of VA content, VE content and VK content is the notice of the newly developed food health measures department manager "About the analysis method of nutritional components etc. in nutrition labeling standards" (April 26, 1999, Eshin No. 13) This was performed according to the high performance liquid chromatograph method defined in 1.
  • the container was stored for 4 weeks under an atmospheric temperature of 25 ° C. while being irradiated with light at an illuminance of 15000 lux. And about the sample after 4 weeks passed from the start of light irradiation, each of VA content, VE content, VK content, VB 6 content, VB 12 content, and folic acid content was measured in the same manner as at the start of storage. .
  • the content of each nutrient component in the sample after light irradiation was divided by the initial value of the content before light irradiation, and the retention rate of each nutrient component after light irradiation with respect to the initial value was calculated.
  • the retention rate was 70% or more, it was evaluated that “the nutrient component was well retained”, that is, “the container has a sufficient light shielding property”.
  • Experiment 4 In order to examine whether or not the content inspection by near infrared rays (wavelength 700 nm to 2500 nm) can be performed in a state where the food or drink is stored in orange and white containers, the following Experiment 4 was performed.
  • an orange container and a white container were prepared. And the light transmittance of these containers was measured.
  • the wavelength was measured in the wavelength range of 250 nm to 2500 nm.
  • the wavelength was scanned in the wavelength range of 500 nm to 2500 nm.
  • an ultraviolet-visible spectrophotometer (model number: SolidSpec-3700DUV) manufactured by Shimadzu Corporation was used.
  • the transmission of near-infrared light through the container means that the quality inspection of the contents by the near-infrared can be performed on the food and drink that are filled in the container.
  • the near-infrared transmittance is 30% or more, the quality inspection of the contents can be sufficiently performed.
  • FIG. 14 is a graph showing the measurement results of Experiment 4. According to FIG. 14, it was found that the orange container has a near-infrared transmittance of 55% or more in the wavelength range of 800 to 2200 nm. In particular, it was found that the transmittance was 70% or more in the wavelength range (1100 to 1150 nm and 1400 to 1600 nm) necessary for examining the state of microbial contamination. On the other hand, it was found that the near-infrared transmittance of the white container was less than 30% over the entire near-infrared wavelength region.
  • Example 5 Enteral nutrition containing a certain amount of enteral nutrients and various microorganisms that do not contain microorganisms, as the container body color is orange (dark), orange (light), brown (dark), and brown (light)
  • the agent was filled and the quality was inspected using “Compovision” manufactured by Sumitomo Electric Industries, Ltd. Then, an experiment was conducted to examine whether or not microorganisms could be detected by measuring reflection through the long wavelength light transmission region of each container body.
  • the present invention is useful for containers that contain enteral nutrients, foods and drinks, and the like.
  • the present invention is useful for enteral nutrients, foods and drinks, and the like hermetically sealed in containers.
  • the present invention is useful for a method for inspecting or producing an enteral nutrient, a food or drink, etc. hermetically sealed in a container.

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  • Engineering & Computer Science (AREA)
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  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Mechanical Engineering (AREA)
  • Chemical & Material Sciences (AREA)
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  • Polymers & Plastics (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • General Physics & Mathematics (AREA)
  • Nutrition Science (AREA)
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  • Analytical Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

L'invention porte sur un récipient (10), qui comporte une ouverture de remplissage (10a) pour permettre le remplissage avec des contenus (1), et des éléments de stockage (11, 12) pour stocker les contenus (1). Les éléments de stockage (11, 12) sont conçus de telle sorte que le facteur de transmission de lumière global des longueurs d'onde de 520 nm ou moins n'est pas supérieur à 75 %. Les éléments de stockage comprennent une région transmettant la lumière des longues longueurs d'onde (10b), dans laquelle le facteur de transmission de lumière des longueurs d'onde de 520 nm ou moins n'est pas supérieur à 75 %, et le facteur de transmission de lumière des longueurs d'onde de 1 100 à 1 150 et de 1 400 à 1 600 est d'au moins 30 %.
PCT/JP2015/065941 2014-06-03 2015-06-02 Récipient, nutriment entéral en récipient ou aliment ou boisson en récipient, procédé pour inspecter un nutriment entéral en récipient ou un aliment ou une boisson en récipient, et procédé pour leur fabrication WO2015186713A1 (fr)

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CN201580030268.2A CN106458420B (zh) 2014-06-03 2015-06-02 容器及容器装经肠营养剂或容器装饮食品和检测制造方法
JP2016525192A JPWO2015186713A1 (ja) 2014-06-03 2015-06-02 容器及び容器入り経腸栄養剤または容器入り飲食品、容器入り経腸栄養剤または容器入り飲食品の検査方法、並びにそれらの製造方法
SG11201610100QA SG11201610100QA (en) 2014-06-03 2015-06-02 Container and containerized enteral nutrient or containerized food/drink product, method of inspecting containerized enteral nutrient or containerized food/drink product, and method of manufacturing the same

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JP2014-115178 2014-06-03

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RU2778515C2 (ru) * 2018-02-28 2022-08-22 Ханлим Фармасьютикал Ко., Лтд. Глазные капли в форме раствора, содержащего производное бензопирана или его фармацевтически приемлемую соль

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RU2778515C2 (ru) * 2018-02-28 2022-08-22 Ханлим Фармасьютикал Ко., Лтд. Глазные капли в форме раствора, содержащего производное бензопирана или его фармацевтически приемлемую соль

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