WO2015085998A1 - Produits cosmétiques antitranspirants sans composés contenant de l'aluminium - Google Patents

Produits cosmétiques antitranspirants sans composés contenant de l'aluminium Download PDF

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Publication number
WO2015085998A1
WO2015085998A1 PCT/DE2014/200498 DE2014200498W WO2015085998A1 WO 2015085998 A1 WO2015085998 A1 WO 2015085998A1 DE 2014200498 W DE2014200498 W DE 2014200498W WO 2015085998 A1 WO2015085998 A1 WO 2015085998A1
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WIPO (PCT)
Prior art keywords
antiperspirant cosmetic
cosmetic agent
weight
antiperspirant
lysozyme
Prior art date
Application number
PCT/DE2014/200498
Other languages
German (de)
English (en)
Inventor
Bernhard Banowski
Melanie Giesen
Original Assignee
Henkel Ag & Co. Kgaa
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Publication date
Application filed by Henkel Ag & Co. Kgaa filed Critical Henkel Ag & Co. Kgaa
Priority to DE112014005630.8T priority Critical patent/DE112014005630A5/de
Publication of WO2015085998A1 publication Critical patent/WO2015085998A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A61K8/66—Enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00—Anti-perspirants or body deodorants

Definitions

  • the present invention relates to an antiperspirant cosmetic composition without aluminum-containing compounds, which contains at least one substance selected from the group of cosmetic oils which are liquid at 20 ° C. and 1013 hPa, fragrances and waxes, and lysozyme, and wherein the addition of the lysozyme in a closure of the sweat gland (s) results.
  • the present invention relates to the use of a combination of at least one selected from the group of cosmetic oils which are liquid at 20 ° C and 1013 hPa, fragrances and waxes, and lysozyme for the reduction and / or prevention of axillary sweat or perspiration of other body regions ,
  • the present invention relates to a non-therapeutic cosmetic method for preventing and / or reducing transpiration of the body, in which the antiperspirant according to the invention is applied to the skin, in particular to the skin of the armpits.
  • the present invention relates to the use of lysozyme for the at least partial closure of the sweat gland (s).
  • washing, cleansing and caring for one's own body is a basic human need, and modern industry is constantly trying to meet these needs of man in a variety of ways. Especially important for daily hygiene is the permanent elimination or at least reduction of body odor and underarm wetness.
  • Numerous specific deodorant or antiperspirant personal care products are known in the art which have been developed for use in body regions having a high density of sweat glands, especially in the underarm area. These are formulated in a wide variety of dosage forms, for example as powder, in stick form, as aerosol spray, pump spray, liquid and gel roll on application, cream, gel and as impregnated flexible substrates (towels).
  • Prior art cosmetic antiperspirants contain at least one antiperspirant salt in addition to at least one oil or fatty substance and one perfume component or perfume.
  • the antiperspirant salts used in antiperspirants reduce sweat secretion of the body through a temporary narrowing and / or obstruction of the excretory ducts of the sweat glands, so that the amount of sweat can be reduced by about 20 to 60 percent.
  • they have an additional deodorizing effect due to their antimicrobial effect.
  • antiperspirant salts usually activated basic aluminum and aluminum zirconium halides are used, as described in the publications EP 0 308 937 A2, EP 0 183 171 A2, US Pat. No. 4,359,456 A and EP 0 191 628. It is also possible to use aluminum and aluminum zirconium halides which are stabilized with organic acids as complexing ligands, as described, for example, in US Pat. Nos. 3,542,919, 3,553,316, 3,991,176 and WO 2005/092795 A1 are disclosed.
  • antiperspirant cosmetic products which, on the one hand, reduce the risks of skin irritation in sensitive skin but, on the other hand, have a satisfactory antiperspirant effect. Furthermore, the antiperspirant cosmetic agents should be inexpensive to produce.
  • the subject of the present invention is thus an antiperspirant cosmetic containing
  • antiperspirant cosmetic agent contains no aluminum-containing compounds.
  • lysozyme in the antiperspirant cosmetic agents according to the invention, gelation of the lysozyme takes place, without wishing to be limited to this theory, only at extremely specific pH values. Due to the extremely selective formation of the gel at pH values, which are exclusively within the excretory ducts of the sweat glands, an effective blockage of the excretory ducts of the sweat glands is ensured, without reducing the antiperspirant effect of the cosmetic product according to the invention by premature undesired gelation due to the addition of lysozyme becomes. Thus, even in the absence of antiperspirant aluminum-containing compounds, effective reduction of armpit sweat is ensured.
  • the lysozyme used in the present invention can be isolated from human sources, animal sources, plants, fungi, bacteria and bacteriophages. In the context of the present invention, preference is given to using lysozyme which is obtained from egg white.
  • antiperspirant is understood according to the invention to reduce or reduce the perspiration of the sweat glands of the body.
  • aluminum-containing compounds is understood to mean antiperspirant aluminum salts and aluminum-zirconium salts.
  • cosmetic oil is understood to mean an oil which is suitable for cosmetic use and which is immiscible with water
  • cosmetic oil used according to the invention is neither fragrance nor essential oils.
  • fragments in the context of the present invention means substances having a molecular weight of 74 to 300 g / mol, which contain at least one osmophoric group in the molecule and have an odor and / or taste, ie they are able to Osmophore groups are groups covalently bound to the molecular skeleton in the form of hydroxy groups, formyl groups, oxo groups, alkoxycarbonyl groups, nitrile groups, nitro groups, azide groups, etc.
  • fragments within the meaning of present invention even at 20 ° C and 1013 hPa liquid perfume oils, perfumes, or perfume oil ingredients.
  • the term "waxes" in the context of the present invention means substances which are kneadable at 20 ° C. or solid to brittle, have a coarse to fine-crystalline structure and are translucent to opaque, but not vitreous, in color Substances above 25 ° C without decomposition, slightly liquid above the melting point (slightly viscous), have a strong temperature-dependent consistency and solubility and are polishable under light pressure.
  • volatile cosmetic oil refers to cosmetic oils which at 20 ° C and an ambient pressure of 1 .013 hPa a vapor pressure of 2.66 Pa to 40,000 Pa (0.02 to 300 mm Hg), preferably from 10 to 12,000 Pa (0.1 to 90 mm Hg), more preferably from 13 to 3000 Pa (0.1 to 23 mm Hg), in particular from 15 to 500 Pa (0.1 to 4 mm Hg) have.
  • nonvolatile cosmetic oils in the context of the present invention means cosmetic oils which have a vapor pressure of less than 2.66 Pa (0.02 mm Hg) at 20 ° C. and an ambient pressure of 1.103 hPa ,
  • fatty acid as used in the present invention means aliphatic carboxylic acids which have unbranched or branched carbon residues of 4 to 40 carbon atoms also be synthetically produced fatty acids.Furthermore, the fatty acids may be monounsaturated or polyunsaturated.
  • fatty alcohol in the context of the present invention means aliphatic, monohydric, primary alcohols which have unbranched or branched hydrocarbon radicals having 4 to 40 carbon atoms
  • the fatty alcohols used in the context of the invention may also be monounsaturated or polyunsaturated ,
  • wt .-% refers in the present case, unless otherwise stated, on the total weight of the antiperspirant cosmetic agents according to the invention without any optional propellant.
  • the cosmetic oil which is liquid at 20 ° C and 1013 hPa is selected from the group of
  • volatile cyclic silicone oils especially cyclotrisiloxane, cyclotetrasiloxane, cyclopentasiloxane and cyclohexasiloxane, and linear silicone oils having 2 to 10 siloxane units, especially hexamethyldisiloxane, octamethyltrisiloxane, decamethyltetrasiloxane;
  • volatile non-silicone oils especially liquid paraffin oils and isoparaffin oils such as isodecane, isoundecane, isododecane, isotridecane, isotetradecane, isopentadecane, isohexadecane and isoeicosan
  • nonvolatile silicone oils especially higher molecular weight linear polyalkylsiloxanes
  • nonvolatile non-silicone oils in particular the esters of linear or branched saturated or unsaturated C 2 to C fatty acids having linear or branched saturated or unsaturated C 2 to C 30 fatty acids which may be hydroxylated, C 8 to C 22 fatty alcohol esters of monovalent or polyvalent C 2 to C fatty acids.
  • C7-hydroxycarboxylic acids the triethyl citrates, the branched saturated or unsaturated C6-3o fatty alcohols, the mono-, di- and triglycerides of linear or branched, saturated or unsaturated, optionally hydroxylated Cs-30 fatty acids, the dicarboxylic acid esters of linear or branched C2 -Cio-alkanols, the adducts of ethylene oxide and / or propylene oxide to mono- or polyhydric C3-22 alkanols, which may be esterified, the symmetrical, asymmetrical or cyclic esters of carbonic acid with fatty alcohols, the esters of dimers of unsaturated Ci2-22 Fatty acids with monovalent, linear, branched and cyclic C2 -is-alkanols or C2-6-alkanols, the benzoic acid esters of linear or branched Cs-22-alkanols such as benzoic acid Ci2-is-al
  • the cyclic volatile silicone oils which can be used in the context of the invention have a vapor pressure of from 13 to 15 Pa (0.1 mm Hg) at 20 ° C. and an ambient pressure of 1013 hPa. Furthermore, according to the invention as a linear volatile silicone oil and a low molecular weight phenyl trimethicone having a vapor pressure of about 2,000 Pa (15 mm Hg) at 20 ° C and an ambient pressure of 1013 hPa can be used.
  • cyclic volatile silicone oils used in the antiperspirant cosmetic agents according to the invention become.
  • volatile non-silicone oils in the form of Cio-13 isoparaffine mixtures having a vapor pressure of from 10 to 400 Pa (0.08 to 3 mm Hg), preferably from 13 to 100 Pa (0.1 to 0.8 mm Hg) , used at 20 ° C and an ambient pressure of 1 .013 hPa.
  • the volatile C8-Ci6-isoparaffin in a total amount of 1 to 60 wt .-%, preferably from 3 to 45 wt .-%, preferably from 5 to 40 wt .-%, in particular from 8 to 20 wt .-%, based on the total weight of the antiperspirant cosmetic agent is included.
  • the volatile C8-Ci6-isoparaffin in a Total amount of 1 to 80 wt .-%, preferably from 3 to 60 wt .-%, preferably from 5 to 50 wt .-%, in particular from 8 to 20 wt .-%, based on the total weight of the antiperspirant cosmetic agent included is.
  • the antiperspirant cosmetic agents contain a non-volatile silicone oil and / or a non-volatile non-silicone oil.
  • preferred antiperspirant cosmetic agents contain at least one ester of linear or branched saturated or unsaturated fatty alcohols having 2 to 30 carbon atoms with linear or branched saturated or unsaturated fatty acids having 2 to 30 carbon atoms, which may be hydroxylated, in a total amount of 1 to 30 wt .-%, preferably from 5 to 26 wt .-%, preferably from 9 to 24 wt .-%, in particular from 12 to 17 wt .-%, based on the total weight of the antiperspirant cosmetic agent.
  • the antiperspirant cosmetic agents of the present invention comprise at least one ester of linear or branched saturated or unsaturated fatty alcohols of 2 to 30 carbon atoms with linear or branched saturated or unsaturated fatty acids of 2 to 30 carbon atoms which may be hydroxylated Total amount of 1 to 80 wt .-%, preferably from 5 to 60 wt .-%, preferably from 9 to 40 wt .-%, in particular from 12 to 25 wt .-%, based on the total weight of the antiperspirant cosmetic agent ,
  • non-volatile silicone oils may be linear polyalkylsiloxanes having a kinematic viscosity of from 5 to 2,000 cSt at 25 ° C., in particular linear polydimethylsiloxanes having a kinematic viscosity at 25 ° C. of from 5 to 2,000 cSt, preferably from 10 to 350 cSt, in particular from 50 to 100 cSt.
  • the non-volatile silicone oils mentioned above are available under the tradenames Dow Corning ® 200 or Xiameter PMX from Dow Corning or Xiameter.
  • nonvolatile silicone oils are phenyltrimethicones having a kinematic viscosity at 25 ° C. of from 10 to 100 cSt, preferably from 15 to 30 cSt, and also cetyldimethicones.
  • the cosmetic oil which is liquid at 20 ° C. and 1 .013 hPa is present in a total amount of from 1 to 95% by weight, preferably from 10 to 85% by weight, preferably from 20 to 75 Wt .-%, more preferably from 35 to 70 wt .-%, in particular from 50 to 60 wt .-%, based on the total weight of the antiperspirant cosmetic agent contained.
  • the antiperspirant compositions according to the invention less than 0.2 wt .-%, preferably less than 0.1 wt .-%, in particular 0 wt .-% of at 20 ° C and 1 .013 hPa liquid cosmetic oil.
  • the use of only extremely small amounts of the cosmetic oil which is liquid at 20 ° C. and 1 .013 hPa is particularly preferred in the case of antiperspirant cosmetic agents according to the invention which are present in aqueous, aqueous-alcoholic or aqueous-glycolic form.
  • the fragrance is selected from the group of
  • esters in particular benzyl acetate, phenoxyethyl isobutyrate, p-tert-butylcyclohexyl acetate, lactyl acetate, dimethylbenzylcarbinylacetate (DMBCA), phenylethylacetate, benzylacetate, ethylmethylphenylglycinate, allylcyclohexylpropionate, styrallylpropionate, benzylsalicylate, cyclohexylsalicylate, floramate, melusate and jasmecyclate;
  • DMBCA dimethylbenzylcarbinylacetate
  • aldehydes especially linear alkanals of 8 to 18 carbon atoms, citral, citronellal, citronellyloxy-acetaldehyde, cyclamen aldehyde, lilial and bourgeonal;
  • ketones especially ionone, alpha-isomethylionone and methyl cedryl ketone
  • alcohols especially anethole, citronellol, eugenol, geraniol, linalool, phenylethyl alcohol and terpineol;
  • hydrocarbons in particular terpenes such as limonene and pinene; such as
  • mixtures of different fragrances are preferably used, which together produce an appealing scent.
  • Particularly appealing antiperspirant cosmetic agents according to the invention are obtained when the perfume in a total amount of 0.00001 to 10 wt .-%, preferably from 0.001 to 9 wt .-%, preferably from 0.01 to 8 wt .-%, more preferably from 0.5 to 7 wt .-%, in particular from 1 to 6 wt .-%, based on the total weight of the antiperspirant cosmetic Means, is included.
  • the fragrance in a total amount of 0.00001 to 5 wt .-%, preferably 0.001 to 4 wt .-%, preferably 0.01 to 3 wt .-%, more preferably 0 , 1 to 2 wt .-%, in particular 0.2 to 1, 5 wt .-%, based on the total weight of the blowing agent-containing antiperspirant cosmetic agent is included.
  • the perfume in a total amount of 0.00001 to 15 wt .-%, preferably 0.001 to 7 wt .-%, preferably 0.01 to 4 wt .-%, more preferably 0.1 to 2 wt .-%, in particular 0.2 to 1, 5 wt .-%, based on the total weight of the antiperspirant cosmetic agent is used.
  • the wax is selected from the group of
  • esters of saturated, monohydric Cs-is alcohols with saturated C12is monocarboxylic acids (iii) esters of saturated, monohydric Cs-is alcohols with saturated C12is monocarboxylic acids
  • esters of a saturated monohydric C 16 -C 60 alkanol and a saturated C 8 -C 36 monocarboxylic acid in particular cetyl behenate, stearyl behenate and C 20 -C 40 -alkyl stearate;
  • glycerol triesters of saturated linear C 12 -C 20 carboxylic acids which may be hydroxylated, in particular hydrogenated palm oil, hydrogenated coconut oil, hydrogenated castor oil, glyceryl tribehenate and glyceryl tri-12-hydroxy stearate;
  • animal waxes in particular beeswax, shellac wax and spermaceti;
  • (ix) synthetic waxes in particular montan ester waxes, hydrogenated jojoba waxes and sasol waxes, polyalkylene waxes and polyethylene glycol waxes, C 2o-C4o dialkyl esters of dimer acids, C 30-50 alkyl beeswax and alkyl and alkylaryl esters of dimer fatty acids, paraffin waxes; such as
  • esters of saturated, monohydric Ci2-i8 alcohols with saturated C12 -is monocarboxylic acids are stearyl laurate, cetearyl stearate (eg Crodamol® CSS), cetyl palmitate (eg Cutina® CP) and myristyl myristate (eg Cetiol® MM).
  • cetearyl stearate eg Crodamol® CSS
  • cetyl palmitate eg Cutina® CP
  • myristyl myristate eg Cetiol® MM
  • Farther It is preferable to use a C2o-C4o-alkyl stearate as the wax component. This ester is known under the name Kester ® K82H or Kesterwachs ® K80H and is sold by Koster Keunen Inc..
  • the wax in a total amount of 0.01 to 50 wt .-%, preferably from 3 to 40 wt .-%, preferably from 5 to 35 wt .-%, in particular from 6 to 25 wt .-%, based on the total weight of the antiperspirant cosmetic agent is included.
  • a particularly effective reduction of underarm perspiration is achieved by gel formation of the lysozyme when the lysozyme is present in a total amount of 0.05 to 15% by weight, preferably 0.1 to 10% by weight, preferably 0 , 3 to 5 wt .-%, more preferably from 0.5 to 7 wt .-%, still more preferably from 0.8 to 5 wt .-%, in particular from 1 to 3 wt .-%, based on the total weight of the antiperspirant cosmetic agent.
  • the cosmetic agent lysozyme in a total amount of 0.05 to 35 wt .-%, preferably from 0.1 to 30 wt .-%, preferably from 0.3 to 20 wt .-%, more preferably from 0.5 to 15 wt .-%, in particular from 0.8 to 10 wt .-%, based on the total weight of the blowing agent-containing antiperspirant cosmetic agent contained.
  • the antiperspirant cosmetic agents it is also possible for the antiperspirant cosmetic agents to contain lysozyme in a total amount of from 0.05 to 35% by weight, preferably from 0.3 to 30% by weight, preferably from 0.5 to 25% by weight.
  • the use of the abovementioned amount of lysozyme results in significantly increased and extremely pH-selective gel formation in the excretory ducts of the sweat glands. In this way, an effective blockage of the excretory ducts of the sweat glands and thus an excellent antiperspirant effect is ensured. Furthermore, the use of the aforementioned amount of lysozyme does not lead to undesirable premature gelation in the antiperspirant cosmetic agent or on the skin surface, so that the excellent antiperspirant effect is ensured even over long storage periods.
  • the antiperspirant cosmetic agent preferably contains free water in a total amount of less than 10% by weight, preferably less than 8% by weight, preferably less than 5% by weight, more preferably less than 3% by weight. even more preferably less than 1% by weight, in particular 0% by weight, based on the total weight of the antiperspirant cosmetic agent.
  • free water is thus understood to mean water, which is different from water of crystallization, water of hydration or similar molecularly bound water of the constituents used.
  • the antiperspirant cosmetic agent therefore contains free water in a total amount of 15 to 96 wt .-%, preferably from 25 to 80 wt .-%, preferably from 30 to 70 wt .-%, in particular of 40 to 60 wt .-%, based on the total weight of the antiperspirant cosmetic agent.
  • the antiperspirant cosmetic agent according to the invention comprises free water in a total amount of from 15 to 99% by weight, preferably from 25 to 90% by weight, preferably from 30 to 80% by weight, in particular from 40 to 60 wt .-%, based on the total weight of the antiperspirant cosmetic agent contains.
  • the antiperspirant cosmetic agent is present as a water-in-oil emulsion.
  • This may in particular be a sprayable water-in-oil emulsion, which can be sprayed by means of a propellant.
  • the antiperspirant cosmetic agent according to the invention present in the form of a water-in-oil emulsion comprises lysozyme in a total amount of from 0.05 to 20% by weight, preferably from 0.1 to 15% by weight.
  • wt .-% preferably from 0.3 to 10 wt .-%, more preferably from 0.5 to 7 wt .-%, still more preferably from 0.8 to 5 wt .-%, in particular from 1 to 3 wt .-% based on the total weight of the antiperspirant cosmetic agent.
  • the antiperspirant cosmetic agent according to the invention lysozyme in a total amount of 0.05 to 35 wt .-%, preferably from 0.1 to 25 wt .-%, preferably from 0.3 to 18 Wt .-%, more preferably from 0.5 to 15 wt .-%, in particular from 1 to 12 wt .-%, based on the total weight of the antiperspirant cosmetic agent contains.
  • the antiperspirant cosmetic agent is present as an oil-in-water emulsion.
  • the agent according to the invention is preferably sprayed as a propellant-free pump spray or squish spray or applied as a roll-on.
  • the antiperspirant cosmetic agent in the form of an oil-in-water emulsion comprises lysozyme in a total amount of 0.05 to 20% by weight, preferably of 0.1 to 15% by weight, preferably from 0.3 to 10% by weight, more preferably from 0.5 to 7% by weight, even more preferably from 0.8 to 5% by weight, in particular from 1 to 3% by weight, based on the total weight of the antiperspirant cosmetic agent contains.
  • the antiperspirant cosmetic agent according to the invention lysozyme in a total amount of 0.05 to 35 wt .-%, preferably from 0.1 to 25 wt .-%, preferably from 0.3 to 18 Wt .-%, more preferably from 0.5 to 15 wt .-%, in particular from 1 to 12 wt .-%, based on the total weight of the antiperspirant cosmetic agent contains.
  • the antiperspirant cosmetic agent is present as an aqueous, aqueous-alcoholic or aqueous-glycolic solution.
  • the cosmetic compositions according to the invention contain no ingredients such as, for example, antiperspirant aluminum-containing compounds which have a reduced antiperspirant effect by the addition of protic solvents, protic solvents, such as aqueous solutions, can be used according to the invention for formulating the antiperspirant cosmetic compositions according to the invention, without a significant reduction the antiperspirant effect occurs. Therefore, the addition of lysozyme, even with the use of protic solvents, ensures effective closure of the excretory ducts of the sweat glands and thus an excellent antiperspirant effect.
  • the antiperspirant cosmetic agent contains ethanol in a total amount of 1 to 99 wt .-%, preferably from 5 to 70 wt .-%, preferably from 7 to 50 wt .-%, in particular from 10 to 30 Wt .-%, based on the total weight of the antiperspirant cosmetic agent.
  • the antiperspirant cosmetic agent ethanol in a total amount of 10 to 95 wt .-%, preferably from 15 to 90 wt .-%, preferably from 20 to 87 wt .-%, more preferably from 30 to 85 wt .-%, in particular from 40 to 80 wt .-%, based on the total weight of the antiperspirant cosmetic agent contains.
  • the use of lysozyme can even use high amounts of protic solvents, such as ethanol, without adversely affecting the antiperspirant effect of the antiperspirant cosmetic agent according to the invention.
  • the pH of the antiperspirant cosmetic agent according to the invention in at least one of the ranges from pH 2.0 to pH 6.0 or pH 7.0 to pH 11, 0, preferably pH 2.5 to pH 5.5 or pH 7.5 to pH 10.0, preferably pH 3.0 to pH 5.0 or pH 8.0 to pH 9.5.
  • the adjustment of the desired pH can be carried out according to the invention by using customary in antiperspirant cosmetic agents acids and bases.
  • the application of the antiperspirant cosmetic agent according to the invention can be carried out by means of various methods.
  • the antiperspirant cosmetic agent is formulated as a spray application.
  • the spray application is carried out with a spray device which contains a filling of the liquid, viscous-flowable, suspension-shaped or powdered antiperspirant cosmetic agent according to the invention in a container.
  • the filling may be under the pressure of a propellant (compressed gas cans, compressed gas packages, aerosol dispensers), or it may be a mechanically operated pump sprayer without propellant (pump sprays / squeeze bottle).
  • the containers have a removal device, preferably in the form of valves, which allow the removal of the contents as a mist, smoke, foam, powder, paste or liquid jet.
  • Cylindrical vessels made of metal (aluminum, tinplate, volume preferably not more than 1 .000 ml), protected or non-splintering glass or plastic (preferably a maximum of 220 ml) or splintering glass or plastic (volume preferably 50) are used as containers for the spraying devices to 400 ml) in question.
  • Creamy, gelatinous, pasty and liquid agents may be packaged, for example, in pump, spray or squeeze dispensers, in particular in multi-chamber pumping, multi-chamber spray or multi-chamber squeeze dispensers.
  • the packaging for the compositions according to the invention may be opaque, but also transparent or translucent.
  • the antiperspirant cosmetic is preferably formulated as a stick, soft solid, cream, roll-on, dibenzylidenalditol-based gel, loose or compact powder.
  • the formulation of the antiperspirant cosmetic agents according to the invention in a particular dosage form such as, for example, an antiperspirant roll-on, an antiperspirant stick or an antiperspirant gel, preferably conforms to the requirements of the intended use.
  • the antiperspirant cosmetic agents according to the invention can therefore be present in solid, semisolid, liquid, disperse, emulsified, suspended, gelatinous, multiphase or powdery form.
  • the term liquid also includes any types of solid dispersions in liquids.
  • multiphase antiperspirant cosmetic agents are also understood to mean agents which have at least two different phases with a phase separation and in which the phases can be arranged horizontally, ie one above the other, or vertically, ie side by side.
  • the application can be done, for example, with a roller ball applicator.
  • rollers have a ball mounted in a ball bed, which can be moved by movement over a surface.
  • the ball absorbs some of the antiperspirant cosmetic agent according to the invention to be distributed and conveys it to the surface to be treated.
  • the packaging for the means according to the invention can, as stated above, be opaque, transparent or translucent.
  • the antiperspirant cosmetic agent is contained on and / or in a disposable substrate selected from the group of wipes, pads and bulbs.
  • a disposable substrate selected from the group of wipes, pads and bulbs.
  • wet wipes i. prefabricated for the user, preferably individually packaged, wet wipes, such as. B. from the field of glass cleaning or from the field of wet toilet paper are well known.
  • Such wet wipes which can advantageously also contain preservatives, are impregnated or applied with an antiperspirant cosmetic agent according to the invention and preferably individually packaged. You can z. B. be used as a deodorant cloth, which is particularly interesting for use on the go.
  • Preferred substrate materials are selected from porous sheet-like cloths.
  • wipes can be made of a fibrous or cellular flexible material which has sufficient mechanical stability and softness for application to the skin.
  • wipes include wipes of woven and nonwoven synthetic and natural fibers, felt, paper or foam, such as hydrophilic polyurethane foam.
  • Deodorizing or antiperspirant substrates which are preferred according to the invention can be obtained by impregnation or impregnation or else by melting a perspiration-inhibiting cosmetic agent according to the invention onto a substrate.
  • the antiperspirant cosmetic agents of the present invention may further contain other adjuvants.
  • the antiperspirant cosmetic agents according to the invention preferably contain at least one wide adjuvant selected from the group of (i) emulsifiers and / or surfactants; (ii) thickeners; (iii) chelating agents; (iv) deodorant agents; (v) monohydric and / or polyhydric alcohols and / or polyethylene glycols; (vi) skin-cooling agents; (vii) propellants; (viii) preservatives; (ix) pH adjusters and (x) mixtures thereof.
  • Emulsifiers and surfactants which are preferably suitable according to the invention are selected from anionic, cationic, nonionic, amphoteric, in particular ampholytic and zwitterionic emulsifiers and surfactants.
  • Surfactants are amphiphilic (bifunctional) compounds which consist of at least one hydrophobic and at least one hydrophilic moiety.
  • the hydrophobic moiety is preferably a hydrocarbon chain of 8 to 28 carbon atoms, which may be saturated or unsaturated, linear or branched. Most preferably, this C8-C28 alkyl chain is linear.
  • anionic surfactants are meant surfactants with exclusively anionic charges; they contain z. As carboxyl groups, sulfonic acid groups or sulfate groups.
  • Particularly preferred anionic surfactants are alkyl sulfates, alkyl ether sulfates, acyl glutamates and Cs-24-carboxylic acids and their salts, the so-called soaps.
  • Cationic surfactants are understood as meaning surfactants with exclusively cationic charges; they contain z.
  • Preferred esterquats are quaternized ester salts of fatty acids with triethanolamine, quaternized ester salts of fatty acids with diethanolalkylamines and quaternized ester salts of fatty acids with 1,2-dihydroxypropyldialkylamines.
  • amphoteric surfactants are subdivided into ampholytic surfactants and zwitterionic surfactants.
  • Ampholytic surfactants are understood as meaning those surface-active compounds which have both acidic (for example -COOH or -SCbH groups) and basic hydrophilic groups (for example amino groups) and thus behave acidic or basic depending on the condition.
  • Zwitterionic surfactants are understood by the person skilled in the art to be surfactants which carry both a negative and a positive charge in the same molecule.
  • Examples of preferred zwitterionic surfactants are the betaines, the N-alkyl-N, N-dimethylammonium glycinates, the N-acyl-aminopropyl-N, N-dimethylammoniumglycinate and the 2-alkyl-3-carboxymethyl-3-hydroxyethyl-imidazoline with each 8 to 24 carbon atoms in the alkyl group.
  • ampholytic surfactants are N-alkylglycines, N-alkylaminopropionic acids, N-alkylaminobutyric acids, N-alkyliminodipropionic acids, N-hydroxyethyl-N-alkylamidopropylglycines, N-alkyltaurines, N-alkylsarcosines, 2-alkylaminopropionic acids and alkylaminoacetic acids each having 8 to 24 carbon atoms in the alkyl group
  • compositions of the invention which are formulated as an emulsion, in particular as an oil-in-water emulsion, preferably contain at least one nonionic oil-in-water emulsifier having an HLB value of more than 7 to 20.
  • nonionic oil-in-water emulsifier having an HLB value of more than 7 to 20.
  • L is the weight fraction of the lipophilic groups, that is the fatty alkyl or fatty acyl groups, in the ethylene oxide adducts, expressed in weight percent.
  • L is the weight fraction of the lipophilic groups, that is the fatty alkyl or fatty acyl groups, in the ethylene oxide adducts, expressed in weight percent.
  • a water-in-oil emulsifier having an HLB value of greater than 1.0 and less than or equal to 7.0 is used.
  • suitable nonionic oil-in-water emulsifiers and suitable Nonionic water-in-oil emulsifiers are described, for example, in German Offenlegungsschrift DE 10 2006 004 957 A1.
  • Substances which are selected from cellulose ethers, especially hydroxyalkylcelluloses, in particular hydroxypropylcellulose, hydroxypropylmethylcellulose, hydroxyethylcellulose, carboxymethylcellulose, cetylhydroxyethylcellulose, hydroxybutylmethylcellulose, methylhydroxyethylcellulose, furthermore xanthan gum, sclerotium gum, succinoglucans, polygalactomannans, are preferably used for thickening the antiperspirant cosmetic agents according to the invention , in particular guar gums and locust bean gum, in particular guar gum and locust bean gum itself and the nonionic hydroxyalkyl guar derivatives and locust bean gum derivatives such as hydroxypropyl guar, carboxymethylhydroxypropyl guar, hydroxypropyl methyl guar, hydroxyethyl guar and carboxymethyl guar, furthermore pectins, agar, carrageenans (Carrageenan), tragacan
  • Particularly preferred thickening agents are selected from cellulose ethers, especially from hydroxyalkylcelluloses, in particular from hydroxypropylcellulose, hydroxypropylmethylcellulose, hydroxyethylcellulose, carboxymethylcellulose, cetylhydroxyethylcellulose, hydroxybutylmethylcellulose and methylhydroxyethylcellulose, and mixtures thereof.
  • Particularly preferred thickeners are furthermore selected from carbomers.
  • Carbomers are thickening crosslinked polymers of acrylic acid, methacrylic acid and their salts.
  • the crosslinking can be effected by means of polyfunctional compounds such as polyalkylene ethers of polysaccharides or polyalcohols, for example sucrose allyl ether, pentaerythritol allyl ether, propylene allyl ether.
  • polyfunctional compounds such as polyalkylene ethers of polysaccharides or polyalcohols, for example sucrose allyl ether, pentaerythritol allyl ether, propylene allyl ether.
  • Preferred in the context of the present invention are homopolymers of acrylic acid or salts thereof which are crosslinked with a pentaerythritol allyl ether, a sucroseallyl ether or a propylene allyl ether.
  • a thickening agent which can be used in the context of the present invention is a copolymer of Cio-30-alkyl acrylate, acrylic acid, methacrylic acid and esters thereof, which is crosslinked with a sucrose allyl ether or a pentaerythritol allyl ether.
  • Thickener based on carbomers are products sold under the trade name Carbopoi ® (BF Goodrich, Ohio, USA) available such as Carbopoi 934, Carbopoi 940, Carbopoi 941, Carbopoi 971, Carbopoi 974, Carbopoi EZ2, Carbopoi ETD 2001 Carbopoi ETD 2020 Carbopoi ETD 2050, Carbopoi uitrez 10, Carbopoi ultrez 20, or Carbopoi uitrez 2.
  • Carbopoi ® BF Goodrich, Ohio, USA
  • the antiperspirant cosmetic agents according to the invention may comprise at least one chelating agent selected from ethylenediaminetetraacetic acid (EDTA) and its salts and from nitrilotriacetic acid (NTA). and mixtures of these substances, in a total amount of 0.01 to 0.5 wt .-%, preferably from 0.02 to 0.3 wt .-%, in particular from 0.05 to 0.1 wt .-%, based on the total weight of the antiperspirant agent according to the invention, to add.
  • EDTA ethylenediaminetetraacetic acid
  • NDA nitrilotriacetic acid
  • chelating agents which are selected from the group consisting of ⁇ -alaninediacetic acid, cyclodextrin, diethylenetriaminepentamethylenephosphonic acid, sodium, potassium, calcium disodium, ammonium and triethanolamine salts of ethylenediaminetetraacetic acid (EDTA), etidronic acid, hydroxyethylethylenediaminetetraacetic acid ( HEDTA) and its sodium salts, sodium salts of nitrilotriacetic acid (NTA), diethylenetriaminepentaacetic acid, phytic acid, hydroxypropyl cyclodextrin, methylcyclodextrin, Aminotrimethylenphosphonat pentasodium, ethylenediamine pentasodium, diethylene pentasodium, pentasodium triphosphate, potassium EDTMP, sodium EDTMP, Natriumdihydroxyethylglycinat, sodium phytate, Natriumpolydi
  • Tetrasodiumiminodisuccinate Tetrasodiumiminodisuccinate, trisodium ethylenediamine disuccinate and desferrioxamine.
  • the antiperspirant effect of the antiperspirant cosmetic agents according to the invention can be further increased if at least one deodorant active ingredient with anti-bacterial and / or bacteriostatic and / or enzyme-inhibiting and / or odor-neutralizing and / or odor-absorbing effect in a total amount of 0.0001 to 40% by weight. %, preferably from 0.2 to 20 wt .-%, preferably from 1 to 15 wt .-%, in particular from 1, 5 to 5 wt .-%, based on the total weight of the antiperspirant cosmetic agent according to the invention, is contained.
  • Deodorant agents which are preferred according to the invention are selected from the group of (i) silver salts; (ii) aromatic alcohols, in particular 2-benzylheptan-1-ol and mixtures of 2-benzylheptan-1-ol and phenoxyethanol; (iii) 1,2-alkanediols having 5 to 12 carbon atoms, especially 3- (2-ethylhexyloxy) -1,2-propanediol; (iv) triethyl citrate; (v) agents against exoesterases, especially against arylsulfatase, lipase, beta-glucuronidase and cystathion-beta-lyase; (vi) cationic phospholipids; (vii) odor absorbers, especially silicates such as montmorillonite, kaoli
  • Preferred antiperspirant cosmetic agents according to the invention also contain at least one water-soluble polyhydric C 2-9 -alkanol having 2 to 6 hydroxyl groups and / or at least one water-soluble polyethylene glycol having 3 to 50 ethylene oxide units and mixtures thereof. This does not include the abovementioned deodorant active ingredients in the form of 1, 2-alkanediols.
  • Preferred alkanols are selected from 1, 2-propylene glycol, 2-methyl-1, 3-propanediol, glycerol, 1, 2-butylene glycol, 1, 3-butylene glycol, 1, 4-butylene glycol, pentylene glycols such as 1, 2-pentanediol and 1, 5-pentanediol, hexanediols such as 1, 2-hexanediol and 1, 6-hexanediol, hexanetriols such as 1, 2,6-hexanetriol, 1, 2-octanediol, 1, 8-octanediol, dipropylene glycol, tripropylene glycol, diglycerol, triglycerol , Erythritol, sorbitol, cis-1,4-dimethylolcyclohexane, trans-1,4-dimethylolcyclohexane, any mixtures of isomers
  • Suitable water-soluble polyethylene glycols are selected from PEG-3, PEG-4, PEG-6, PEG-7, PEG-8, PEG-9, PEG-10, PEG-12, PEG-14, PEG-16, PEG-18 and PEG-20 and mixtures thereof, with PEG-3 to PEG-8 being preferred.
  • the antiperspirant cosmetic agents further contain at least one skin-cooling agent.
  • Skin-cooling active ingredients suitable according to the invention are, for example, menthol, isopulegol and menthol derivatives, eg. Eg menthyl lactate, menthyl glycolate, menthyl ethyl oxamate, menthyl pyrrolidone carboxylic acid, menthyl methyl ether, menthoxy propane diol, menthone glycerol acetal (9-methyl-6- (1-methylethyl) -1, 4-dioxaspiro (4.5) decane-2-methanol), monomethyl succinate, 2 -Hydroxymethyl-3,5,5-trimethylcyclohexanol and 5-methyl-2- (1-methylethyl) cyclohexyl-N-ethyloxamate.
  • Preferred skin-cooling active ingredients are menthol, isopulegol, menthyl lactate, menthoxypropanediol, menthylpyrrolidonecarboxylic acid and 5-methyl-2- (1-methylethyl) cyclohexyl-N-ethyloxamate, as well as mixtures of these substances, in particular mixtures of menthol and menthyl lactate, menthol, menthol glycolate and menthyl lactate, menthol and menthoxypropanediol or menthol and isopulegol.
  • the antiperspirant cosmetic agents according to the invention contain a propellant.
  • propellants are propane, propene, n-butane, isobutane, isobutene, n-pentane, pentene, isopentane, isopentene, methane, ethane, dimethyl ether, nitrogen, air, oxygen, nitrous oxide, 1, 1, 1, 3-tetrafluoroethane, heptafluoro-n-propane, perfluoroethane, monochlorodifluoromethane, 1, 1 - difluoroethane, tetrafluoropropenes, both individually and in their mixtures.
  • hydrophilic propellants such as carbon dioxide
  • hydrophilic propellants such as carbon dioxide
  • lipophilic propellant gas eg., Propane / butane
  • propane, n-butane, isobutane and mixtures of these propellants propane, n-butane, isobutane and mixtures of these propellants. It has been found that the use of n-butane as the only propellant gas according to the invention can be particularly preferred.
  • the total amount of blowing agent is 20 to 95 wt.%, Preferably 30 to 85 wt.%, In particular 40 to 75 wt .-%, each based on the total weight of the antiperspirant consisting of the antiperspirant cosmetic agent of the invention, the propellant and optionally other excipients.
  • the total amount of blowing agent 1 to 95 wt .-%, preferably 2 to 85 wt .-%, in particular 3 to 75 wt .-%, .-%, each based on the total weight of Antiperspirant, consisting of the antiperspirant cosmetic agent of the invention and the propellant is.
  • lipophilic thickeners can furthermore be used according to the invention.
  • the lysozyme is suspended undissolved in at least one at 20 ° C and 1 .013 hPa liquid cosmetic oil.
  • at least one lipophilic thickener may be added to this suspension as a suspending aid.
  • Lipophilic thickeners preferred according to the invention are selected from hydrophobized clay minerals and fumed silicic acids.
  • the antiperspirant cosmetic agents of the present invention may further contain at least one preservative.
  • Preservatives preferred according to the invention are formaldehyde releasers (such as, for example, 1,3-dimethylol-4,4-dimethylhydantoin, INCI name DMDM hydantoin, available, for example, under the trade name Glydant from Lonza), iodopropynyl butyl carbamates, such as 3-iodo-2-propynyl butyl carbamate (e.g., those available under the trade designations Glycacil-L, Glycacil-S from Lonza, and / or Dekaben LMB from Jan Dekker), parabens (ie, p-hydroxybenzoic acid alkyl esters, such as methyl, ethyl , Propyl and / or butylparaben), phenoxyethanol, ethanol, benzoic acid, dibromodicyanobut
  • preservatives which can be used in the context of the present invention are the substances listed in Annex 6 of the Cosmetics Regulation.
  • the preservatives are preferably in a total amount of 0.01 to 10 wt .-%, preferably from 0.1 to 7 wt .-%, preferably from 0.2 to 5 wt .-%, in particular from 0.3 to 2, 0 wt .-%, based on the total weight of the antiperspirant cosmetic agent included.
  • the pH adjusting agents used are preferably acids and / or alkalizing agents and / or buffers.
  • acids according to the invention preferably mineral acids (such as hydrochloric acid, sulfuric acid or phosphoric acid) or edible acids (such as citric acid, tartaric acid or malic acid) are used.
  • the alkalizing agents usable in the present invention are preferably selected from the group consisting of ammonia, basic amino acids, alkali hydroxides, alkanolamines, alkali metal metasilicates, urea, morpholine, N-methylglucamine, imidazole, alkali phosphates and alkali hydrogen phosphates.
  • the alkali metal ions used are preferably lithium, sodium, potassium, in particular sodium or potassium.
  • the basic amino acids which can be used as alkalizing agents according to the invention are preferably selected from the group formed from L-arginine, D-arginine, D, L-arginine, L-histidine, D-histidine, D, L-histidine, L-lysine, D-lysine, D, L-lysine, more preferably L-arginine, D-arginine, D, L-arginine used as an alkalizing agent according to the invention.
  • the alkali metal hydroxides which can be used as the alkalizing agent according to the invention are preferably selected from the group formed from sodium hydroxide and potassium hydroxide.
  • alkanolamines which can be used as alkalizing agents according to the invention are preferably selected from primary amines having a C 2 -C 6 -alkyl basic body which carries at least one hydroxyl group.
  • Particularly preferred alkanolamines are selected from the group formed from 2-aminoethane-1-ol (monoethanolamine), 3-aminopropan-1-ol, 4-aminobutan-1-ol, 5-aminopentan-1-ol, 1 - aminopropan-2-ol, 1-aminobutan-2-ol, 1-aminopentan-2-ol, 1-aminopentan-3-ol, 1-aminopentan-4-ol, 3-amino-2-methylpropan-1-ol , 1-amino-2-methylpropan-2-ol, 3-aminopropane-1, 2-diol, 2-amino-2-methylpropane-1,3-diol.
  • Suitable buffer systems in the context of the present invention are, in particular, carbonic acid bicarbonate buffers, carbonic acid silicate buffers, acetic acid acetate buffers, phosphate buffers, ammonia buffers, citric acid or citrate buffers, buffers based on tris (hydroxymethyl) aminomethane, buffers Base of 4- (2-hydroxyethyl) -1-piperazineethanesulfonic acid, buffer based on 4- (2-hydroxyethyl) piperazine-1-propanesulfonic acid, buffer based on 2- (N-morpholino) ethanesulfonic acid and barbital acetate buffer , The choice of the corresponding buffer system depends on the desired pH of the antiperspirant cosmetic composition according to the invention.
  • the antiperspirant cosmetic agents according to the invention are characterized in that they are formulated as a water-in-oil emulsion and, based on the total weight of the antiperspirant cosmetic agent according to the invention,
  • Lysozyme in a total amount of 0.05 to 20 wt .-%, preferably 0.1 to 15 wt .-%, preferably 0.3 to 10 wt .-%, more preferably 0.5 to 7 wt .-%, even more preferably 0.8 to 5% by weight, in particular 1 to 3% by weight,
  • the lysozyme in a total amount of 0.05 to 35 wt .-%, preferably from 0.1 to 15 wt .-%, preferably 0.3 to 10 wt. %, more preferably 0.5 to 7 wt .-%, even more preferably 0.8 to 5 wt .-%, in particular 1 to 3 wt .-% and water in a total amount of 12 to 99 wt .-%, respectively based on the total weight of the antiperspirant cosmetic agent.
  • the antiperspirant cosmetic agents according to the invention are characterized in that they are formulated as an oil-in-water emulsion and, based on the total weight of the antiperspirant cosmetic agent according to the invention,
  • Lysozyme in a total amount of 0.05 to 20 wt .-%, preferably 0.1 to 15 wt .-%, preferably 0.3 to 10 wt .-%, more preferably 0.5 to 7 wt .-%, even more preferably 0.8 to 5% by weight, in particular 1 to 3% by weight,
  • the lysozyme is present in a total amount of from 0.05 to 35% by weight, preferably from 0.1 to 15% by weight, preferably from 0.3 to 10% by weight. , more preferably 0.5 to 7 wt .-%, still more preferably 0.8 to 5 wt .-%, in particular 1 to 3 wt .-% and water in a total amount of 12 to 98 wt .-%, each based on the total weight of the antiperspirant cosmetic agent.
  • a further preferred embodiment of the present invention comprises antiperspirant cosmetic agents according to the invention, which are characterized in that they contain, based on the total weight of the antiperspirant cosmetic agent according to the invention,
  • Lysozyme in a total amount of 0.05 to 20 wt .-%, preferably 0.1 to 15 wt .-%, preferably 0.3 to 10 wt .-%, more preferably 0.5 to 7 wt .-%, even more preferably 0.8 to 5% by weight, in particular 1 to 3% by weight,
  • lysozyme in a total amount of 0.05 to 35 wt .-%, preferably from 0.1 to 15 wt .-%, preferably 0.3 to 10 wt.
  • % more preferably 0.5 to 7 wt .-%, still more preferably 0.8 to 5 wt .-%, in particular 1 to 3 wt .-%, water in a total amount of 12 to 98 wt .-% and thickening agent in a total amount of 0.01 to 5 wt .-%, each based on the total weight of the antiperspirant cosmetic agent is included.
  • a further preferred embodiment of the present invention comprises antiperspirant cosmetic agents according to the invention, which are characterized in that they contain, based on the total weight of the antiperspirant cosmetic agent according to the invention,
  • Lysozyme in a total amount of 0.05 to 20 wt .-%, preferably 0.1 to 15 wt .-%, preferably 0.3 to 10 wt .-%, more preferably 0.5 to 7 wt .-%, even more preferably 0.8 to 5% by weight, in particular 1 to 3% by weight,
  • the antiperspirant cosmetic agents according to the invention have a dynamic viscosity in the range from 10 to 5000 mPas, preferably from 100 to 1000 mPas, preferably from 200 to 800 mPas, measured with a Brookfield viscometer, spindle RV 4, 20 s, without Helipath at 20 ° C ambient temperature and 20 ° C sample temperature.
  • the lysozyme in a total amount of 0.05 to 35 wt .-%, preferably from 0.1 to 15 wt .-%, preferably 0.3 to 10 wt.
  • % more preferably 0.5 to 7 wt .-%, still more preferably 0.8 to 5 wt .-%, in particular 1 to 3 wt .-%, water in a total amount of 12 to 98 wt .-% and thickening agent in a total amount of 0.01 to 5 wt .-%, each based on the total weight of the antiperspirant cosmetic agent is included.
  • a further preferred embodiment of the present invention comprises antiperspirant cosmetic agents according to the invention, which are characterized in that they contain, based on the total weight of the antiperspirant cosmetic agent according to the invention,
  • Lysozyme in a total amount of 0.05 to 35 wt .-%, preferably from 0.1 to 15 wt .-%, preferably 0.3 to 10 wt .-%, more preferably 0.5 to 7 wt .-% , even more preferably 0.8 to 5% by weight, in particular 1 to 3% by weight,
  • the antiperspirant cosmetic agents according to the invention have a dynamic viscosity in the range of 1 .000 to 800,000 mPas, preferably from 2,000 to 700,000 mPas, preferably from 3,000 to 500,000 mPas, measured with a Brookfield viscometer, spindle RV 4, 20 s "1 , without Helipath, at 20 ° C ambient temperature and 20 ° C sample temperature.
  • the antiperspirant cosmetic agents according to the invention are characterized in that they are formulated as a water-in-oil emulsion and, based on the total weight of the antiperspirant cosmetic agent according to the invention,
  • Lysozyme in a total amount of 0.05 to 20 wt .-%, preferably 0.1 to 15 wt .-%, preferably 0.3 to 10 wt .-%, more preferably 0.5 to 7 wt .-%, even more preferably 0.8 to 5% by weight, in particular 1 to 3% by weight,
  • the lysozyme in a total amount of 0.05 to 35 wt .-%, preferably from 0.1 to 15 wt .-%, preferably 0.3 to 10 wt. %, more preferably 0.5 to 7 wt .-%, still more preferably 0.8 to 5 wt .-%, in particular 1 to 3 wt .-% and water in a total amount of 12 to 98 wt .-%, respectively based on the total weight of the antiperspirant cosmetic agent.
  • the antiperspirant cosmetic agents according to the invention are characterized in that they are formulated as an oil-in-water emulsion and, based on the total weight of the antiperspirant cosmetic agent according to the invention,
  • Lysozyme in a total amount of 0.05 to 20 wt .-%, preferably 0.1 to 15 wt .-%, preferably 0.3 to 10 wt .-%, more preferably 0.5 to 7 wt .-%, even more preferably 0.8 to 5% by weight, in particular 1 to 3% by weight,
  • Wt .-% in particular 0.3 to 0.5 wt .-% of a thickener
  • the lysozyme in a total amount of 0.05 to 35 wt .-%, preferably from 0.1 to 15 wt .-%, preferably 0.3 to 10 wt. %, more preferably 0.5 to 7% by weight, even more preferably 0.8 to 5% by weight, in particular 1 to 3% by weight, of water in a total amount of 12 to 98% by weight and thickening agent in a total amount of 0.01 to 5 wt .-% "in each case based on the total weight of the antiperspirant cosmetic agent is included.
  • compositions according to the invention can therefore, as kit-of-parts, containing, separated from one another, a) at least one first container containing a cosmetic agent comprising at least one antiperspirant aluminum-containing compound, and
  • aluminum-containing compounds is understood to mean antiperspirant aluminum salts and aluminum-zirconium salts.
  • a second object of the present invention is the use of a combination of at least one selected from the group of cosmetic oils which are liquid at 20 ° C and 1 .013 hPa, fragrances and waxes, and lysozyme for the reduction and / or prevention of perspiration ,
  • the term "combination" within the meaning of the present invention also encompasses a mixture of the at least one substance with lysozyme.
  • a third aspect of the present invention is a non-therapeutic cosmetic method for preventing and / or reducing transpiration of the body, which comprises an antiperspirant cosmetic agent containing at least one selected from the group of cosmetic oils at 20 ° C and 1013 hPa are liquid, fragrances and waxes, and lysozyme, applied to the skin, especially to the skin of the underarms.
  • a cosmetic agent containing an antiperspirant aluminum salt and then the cosmetic agent according to the invention containing lysozyme is applied.
  • the time span between the application of the two remedies is from 10 seconds to 24 hours.
  • a fourth object of the present invention is the use of lysozyme for the at least partial closure of the sweat gland (s).
  • Closure formation of the sweat gland (s) is understood to mean the formation of a gel and / or precipitate of lysozyme in the excretory duct of the sweat gland or the excretory ducts of the sweat glands. This occlusion avoids or reduces secretion of sweat from the duct.
  • lysozyme according to the invention, what has been said about the cosmetic antiperspirant agents according to the invention applies mutatis mutandis.
  • Antiperspirant cosmetic agents according to the invention (amounts in% by weight)
  • compositions according to the invention in the form of an oil-in-water emulsion (amounts in% by weight)
  • Antiperspirant cosmetic agents according to the invention in the form of microemulsions (in% by weight)
  • Antiperspirant cosmetic compositions according to the invention in the form of roll-ons (amounts in% by weight)
  • Hydroxyethylcellulose 0.50 0.50 0.30 0.30 0.50
  • a single-layer substrate of 100% viscose having a weight per unit area of 50 g / m 2 was applied to 75 g each of the exemplary emulsions 13 or 14 per square meter or 75 g each of the exemplary compositions 10 and 11, respectively , cut into cloths of suitable size and packed in sachets.
  • Antiperspirant cosmetic agents according to the invention in the form of a water-in-oil emulsion (amounts in% by weight)
  • Antiperspirant cosmetic agents according to the invention (amounts in% by weight)
  • Antiperspirant cosmetic agents according to the invention with a pH of 3.0 to 5.0 (amounts in% by weight)
  • Antiperspirant cosmetic agents according to the invention (amounts in% by weight, based on the total weight of the blowing agent-free composition)
  • Example Compositions 29-32 were packed in an optionally epoxy-phenolic varnish-sprayed aluminum spray can in a weight ratio of propellant (butane / propane / isobutane mixture) to suspension of 80:20, 85:15, 60:40 and 90:10, respectively.
  • propellant butane / propane / isobutane mixture
  • Antiperspirant cosmetic agents according to the invention (amounts in% by weight, based on the total weight of the blowing agent-free composition)
  • Example compositions 33-35 were charged to an aluminum spray can optionally coated with epoxy-phenolic paint in a weight ratio of propellant (butane / propane / isobutane mixture) to suspension of 80:20, 85:15, 60:40 and 90:10, respectively.
  • propellant butane / propane / isobutane mixture
  • Antiperspirant cosmetic agents according to the invention in the form of O / W emulsions (amounts in parts by weight)
  • Antiperspirant cosmetic agents according to the invention (amounts in% by weight, based on the total weight of the blowing agent-free composition)
  • Example Compositions 39-42 were packed into an optionally epoxy-phenolic varnish-sprayed aluminum spray can in a weight ratio of propellant (butane / propane / isobutane mixture) to suspension of 80:20, 85:15, 60:40 and 90:10, respectively.
  • propellant butane / propane / isobutane mixture
  • Antiperspirant cosmetic compositions according to the invention in the form of W / O emulsions (amounts in% by weight)
  • Plantar ® 2000 DECYL GLUCOSIDE about 50% AS BASF

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Abstract

La présente invention concerne un produit cosmétique antitranspirant, contenant a) au moins une substance choisie dans le groupe constitué par les huiles cosmétiques qui sont à l'état liquide à une température de 20 °C et sous une pression de 1,013 hPa, les parfums et les cires et b) du lysozyme, ce produit cosmétique antitranspirant étant exempt de composés contenant de l'aluminium. L'ajout de lysozyme garantit un blocage efficace des canaux excréteurs des glandes sudoripares et a pour effet une réduction efficace de l'hyperhidrose axillaire, même en l'absence de sels d'aluminium antitranspirants. Ce produit cosmétique antitranspirant sans composés contenant de l'aluminium est adapté en particulier aux peaux sensibles.
PCT/DE2014/200498 2013-12-11 2014-09-23 Produits cosmétiques antitranspirants sans composés contenant de l'aluminium WO2015085998A1 (fr)

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WO2017008930A1 (fr) * 2015-07-16 2017-01-19 Henkel Ag & Co. Kgaa Procédé de réduction de la transpiration et/ou des odeurs corporelles à l'aide de composés phosphate
WO2017202556A1 (fr) * 2016-05-23 2017-11-30 Henkel Ag & Co. Kgaa Préparation antitranspirante
CN117717492A (zh) * 2023-12-19 2024-03-19 中山自然说生物科技有限公司 一种修复腋窝微生态的生物制剂及其制备方法和应用

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EP3185966A1 (fr) * 2014-08-26 2017-07-05 Henkel AG & Co. KGaA Produits cosmétiques anti-transpirants contenant des protéines spéciales issues de sources humaines ou animales ou des protéines spéciales issues de poissons ou d'oiseaux ou d'oeufs, ne renfermant pas d'halogénures et/ou d'hydroxyhalogénures d'aluminium et/ou de zirconium
DE102016208859A1 (de) 2016-05-23 2017-11-23 Henkel Ag & Co. Kgaa Desodorierende Wirkstoffkombination
DE102016208858A1 (de) 2016-05-23 2017-11-23 Henkel Ag & Co. Kgaa Desodorierende Wirkstoffkombination
DE102016208863A1 (de) 2016-05-23 2017-03-02 Henkel Ag & Co. Kgaa Desodorierende Wirkstoffkombination
DE102016208856A1 (de) 2016-05-23 2017-11-23 Henkel Ag & Co. Kgaa Desodorierende Wirkstoffkombination
DE102019134443B4 (de) 2019-12-16 2022-01-20 Henkel Ag & Co. Kgaa Schweißhemmendes kosmetisches Mittel umfassend Dimethylglucamin
DE102020100839A1 (de) 2020-01-15 2021-07-15 Henkel Ag & Co. Kgaa Polyphosphazene als Antitranspirant-Wirkstoff
DE102020101190A1 (de) 2020-01-20 2021-07-22 Henkel Ag & Co. Kgaa Salze zyklischer Amine zur Verminderung der Schweißsekretion

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WO2017008930A1 (fr) * 2015-07-16 2017-01-19 Henkel Ag & Co. Kgaa Procédé de réduction de la transpiration et/ou des odeurs corporelles à l'aide de composés phosphate
WO2017202556A1 (fr) * 2016-05-23 2017-11-30 Henkel Ag & Co. Kgaa Préparation antitranspirante
US10980734B2 (en) 2016-05-23 2021-04-20 Henkel Ag & Co. Kgaa Antiperspirant preparation
CN117717492A (zh) * 2023-12-19 2024-03-19 中山自然说生物科技有限公司 一种修复腋窝微生态的生物制剂及其制备方法和应用

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