WO2015065009A1 - Procédé d'encapsulation physique, dans une particule d'hydrogel, d'un liposome contenant une substance active, et composition cosmétique contenant celle-ci - Google Patents

Procédé d'encapsulation physique, dans une particule d'hydrogel, d'un liposome contenant une substance active, et composition cosmétique contenant celle-ci Download PDF

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Publication number
WO2015065009A1
WO2015065009A1 PCT/KR2014/010180 KR2014010180W WO2015065009A1 WO 2015065009 A1 WO2015065009 A1 WO 2015065009A1 KR 2014010180 W KR2014010180 W KR 2014010180W WO 2015065009 A1 WO2015065009 A1 WO 2015065009A1
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WO
WIPO (PCT)
Prior art keywords
liposome
active ingredient
hydrogel particles
weight
hydrogel
Prior art date
Application number
PCT/KR2014/010180
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English (en)
Korean (ko)
Inventor
류재호
김성열
Original Assignee
화코스텍 주식회사
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 화코스텍 주식회사 filed Critical 화코스텍 주식회사
Priority to CN201480056353.1A priority Critical patent/CN105658204A/zh
Publication of WO2015065009A1 publication Critical patent/WO2015065009A1/fr

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04Dispersions; Emulsions
    • A61K8/042Gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11Encapsulated compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/14Liposomes; Vesicles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35Ketones, e.g. benzophenone
    • A61K8/355Quinones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/671Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/68Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5026Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/06Preparations for styling the hair, e.g. by temporary shaping or colouring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00Preparations for affecting hair growth

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)

Abstract

La présente invention concerne un procédé de préparation pour encapsuler physiquement, dans une particule d'hydrogel, un liposome contenant une substance active liposoluble, et plus particulièrement, concerne un procédé pour fixer physiquement un liposome à un réseau réticulé d'hydrogel par : préparation d'un liposome contenant au moins une substance active liposoluble in vivo parmi un dérivé de phytosphingosine, le rétinol et un dérivé de celui-ci, un céramide, l'idébénone, et un agent de croissance des cheveux ou tonifiant pour les cheveux faiblement hydrosoluble ; obtention d'une émulsion E/H contenant, dans une phase aqueuse, le liposome préparé de cette manière en utilisant un procédé de mélange de fluide en flux ; et réticulation de polymère sélective uniquement de la phase aqueuse. Un film d'hydrogel n'est pas rompu par un tensioactif ou un sel même après que des particules de liposome-hydrogel préparées par la présente invention ont été mélangées dans une composition cosmétique, et donc un liposome contenant une substance active est encapsulé de façon stable à l'intérieur d'une particule d'hydrogel.
PCT/KR2014/010180 2013-10-29 2014-10-28 Procédé d'encapsulation physique, dans une particule d'hydrogel, d'un liposome contenant une substance active, et composition cosmétique contenant celle-ci WO2015065009A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201480056353.1A CN105658204A (zh) 2013-10-29 2014-10-28 将含有活性成分的脂质体物理性地包合在水凝胶粒子的方法及含有其的化妆品组合物

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020130129275A KR101376135B1 (ko) 2013-10-29 2013-10-29 활성성분이 함유된 리포좀을 하이드로젤 입자에 물리적으로 포접하는 방법 및 이를 함유하는 화장료 조성물
KR10-2013-0129275 2013-10-29

Publications (1)

Publication Number Publication Date
WO2015065009A1 true WO2015065009A1 (fr) 2015-05-07

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PCT/KR2014/010180 WO2015065009A1 (fr) 2013-10-29 2014-10-28 Procédé d'encapsulation physique, dans une particule d'hydrogel, d'un liposome contenant une substance active, et composition cosmétique contenant celle-ci

Country Status (3)

Country Link
KR (1) KR101376135B1 (fr)
CN (1) CN105658204A (fr)
WO (1) WO2015065009A1 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102555803B1 (ko) * 2015-12-24 2023-07-14 코웨이 주식회사 하이드로젤 캡슐, 이의 제조방법 및 이를 포함하는 화장료 조성물
CN107496358A (zh) * 2017-09-06 2017-12-22 苏州大学 一种脂质体增强型水凝胶及其应用
CN108210937A (zh) * 2018-02-08 2018-06-29 上海应用技术大学 吡咯烷基二氨基嘧啶氧化物β-环糊精基包合物及其制备方法
CN108467464A (zh) * 2018-04-02 2018-08-31 常熟理工学院 含壬二酸可见光固化水凝胶及其制备方法
CN108619171A (zh) * 2018-05-05 2018-10-09 东莞市联洲知识产权运营管理有限公司 一种含蛋黄油/脂质体的电磁屏蔽医用凝胶材料的制备方法
CN112168753A (zh) * 2020-09-30 2021-01-05 云南贝泰妮生物科技集团股份有限公司 一种具有屏障修护功效的活性粒子及其制备工艺

Citations (5)

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KR20060015534A (ko) * 2003-04-25 2006-02-17 더 펜 스테이트 리서치 파운데이션 성장 억제, 지질 유래된 생활성 화합물의 전신 전달을 위한방법 및 시스템
KR100852944B1 (ko) * 2007-02-15 2008-08-19 (주)아모레퍼시픽 화학적으로 가교된 히알루론산 하이드로겔 나노입자의제조방법
KR20110037863A (ko) * 2009-10-06 2011-04-13 엘브이엠에이취 러쉐르쉐 옥사졸리딘-2-온 화합물을 캡슐화한 리포좀
KR20120037639A (ko) * 2010-10-12 2012-04-20 (주) 화천 소듐폴리감마글루타메이트의 효능극대화를 위한 캡슐화 방법 및 이를 포함하는 화장료
KR20130039058A (ko) * 2011-10-11 2013-04-19 주식회사 제닉 에멀젼화된 하이드로겔 조성물 및 이의 제조방법

Family Cites Families (1)

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Patent Citations (5)

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Publication number Priority date Publication date Assignee Title
KR20060015534A (ko) * 2003-04-25 2006-02-17 더 펜 스테이트 리서치 파운데이션 성장 억제, 지질 유래된 생활성 화합물의 전신 전달을 위한방법 및 시스템
KR100852944B1 (ko) * 2007-02-15 2008-08-19 (주)아모레퍼시픽 화학적으로 가교된 히알루론산 하이드로겔 나노입자의제조방법
KR20110037863A (ko) * 2009-10-06 2011-04-13 엘브이엠에이취 러쉐르쉐 옥사졸리딘-2-온 화합물을 캡슐화한 리포좀
KR20120037639A (ko) * 2010-10-12 2012-04-20 (주) 화천 소듐폴리감마글루타메이트의 효능극대화를 위한 캡슐화 방법 및 이를 포함하는 화장료
KR20130039058A (ko) * 2011-10-11 2013-04-19 주식회사 제닉 에멀젼화된 하이드로겔 조성물 및 이의 제조방법

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KR101376135B1 (ko) 2014-03-19
CN105658204A (zh) 2016-06-08

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