WO2015059683A1 - Plant-based composition for use in the treatment of cough - Google Patents

Plant-based composition for use in the treatment of cough Download PDF

Info

Publication number
WO2015059683A1
WO2015059683A1 PCT/IB2014/065643 IB2014065643W WO2015059683A1 WO 2015059683 A1 WO2015059683 A1 WO 2015059683A1 IB 2014065643 W IB2014065643 W IB 2014065643W WO 2015059683 A1 WO2015059683 A1 WO 2015059683A1
Authority
WO
WIPO (PCT)
Prior art keywords
natural
flavour
cough
extract
honey
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2014/065643
Other languages
English (en)
French (fr)
Inventor
Valentino Mercati
Anna MAIDECCHI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aboca SpA Societa Agricola
Original Assignee
Aboca SpA Societa Agricola
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aboca SpA Societa Agricola filed Critical Aboca SpA Societa Agricola
Priority to ES14809976T priority Critical patent/ES2743210T3/es
Priority to BR112016008876-0A priority patent/BR112016008876B1/pt
Priority to US15/032,051 priority patent/US10588933B2/en
Priority to MX2016005359A priority patent/MX374590B/es
Priority to PL14809976T priority patent/PL3060224T3/pl
Priority to CN201480058509.XA priority patent/CN105764519B/zh
Priority to CA2928551A priority patent/CA2928551C/en
Priority to EA201690597A priority patent/EA037173B1/ru
Priority to EP14809976.5A priority patent/EP3060224B1/en
Publication of WO2015059683A1 publication Critical patent/WO2015059683A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/64—Insects, e.g. bees, wasps or fleas
    • A61K35/644—Beeswax; Propolis; Royal jelly; Honey
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/68—Plantaginaceae (Plantain Family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents

Definitions

  • the mucous membrane lining the respiratory tract plays a protective role of functional barrier between the external environment and the tissues:
  • the mucus covering it which is an adhesive, viscoelastic gel produced by goblet cells and whose main macromolecules are glycoproteins.
  • composition for use in the treatment of cough, comprising Plantago lanceolata, a.k.a. "plantain”, extract, cane sugar, honey, Thymus sp. extract, a.k.a. "thyme”), optionally comprising also Sambucus nigra, a.k.a. "elderberry", juice .
  • the juice could be prepared according to standard techniques known to a person skilled in the art.
  • Table 1 below synthetically reports for the different functional components (active principles) listed above, the physico-mechanical effect carried out and the plant or natural substance from which it derives.
  • liquid formulation is provided which are not to be understood as a limitation of the application.

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Insects & Arthropods (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
PCT/IB2014/065643 2013-10-25 2014-10-27 Plant-based composition for use in the treatment of cough Ceased WO2015059683A1 (en)

Priority Applications (9)

Application Number Priority Date Filing Date Title
ES14809976T ES2743210T3 (es) 2013-10-25 2014-10-27 Composición basada en plantas para su utilización en el tratamiento de la tos
BR112016008876-0A BR112016008876B1 (pt) 2013-10-25 2014-10-27 Composição para utilização no tratamento de tosse, e processo para a preparação da composição
US15/032,051 US10588933B2 (en) 2013-10-25 2014-10-27 Plant-based composition for use in the treatment of cough
MX2016005359A MX374590B (es) 2013-10-25 2014-10-27 Composición para usarse en el tratamiento de la tos.
PL14809976T PL3060224T3 (pl) 2013-10-25 2014-10-27 Kompozycja roślinna do stosowania w leczeniu kaszlu
CN201480058509.XA CN105764519B (zh) 2013-10-25 2014-10-27 用于治疗咳嗽的基于植物的组合物
CA2928551A CA2928551C (en) 2013-10-25 2014-10-27 Composition for use in the treatment of cough
EA201690597A EA037173B1 (ru) 2013-10-25 2014-10-27 Композиция для применения при лечении кашля
EP14809976.5A EP3060224B1 (en) 2013-10-25 2014-10-27 Plant-based composition for use in the treatment of cough

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITRM2013A000592 2013-10-25
IT000592A ITRM20130592A1 (it) 2013-10-25 2013-10-25 Composizione per la tosse.

Publications (1)

Publication Number Publication Date
WO2015059683A1 true WO2015059683A1 (en) 2015-04-30

Family

ID=49725273

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2014/065643 Ceased WO2015059683A1 (en) 2013-10-25 2014-10-27 Plant-based composition for use in the treatment of cough

Country Status (13)

Country Link
US (1) US10588933B2 (https=)
EP (1) EP3060224B1 (https=)
CN (1) CN105764519B (https=)
BR (1) BR112016008876B1 (https=)
CA (1) CA2928551C (https=)
EA (1) EA037173B1 (https=)
ES (1) ES2743210T3 (https=)
HU (1) HUE046608T2 (https=)
IT (1) ITRM20130592A1 (https=)
MX (1) MX374590B (https=)
PL (1) PL3060224T3 (https=)
PT (1) PT3060224T (https=)
WO (1) WO2015059683A1 (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITUA20163755A1 (it) * 2016-05-24 2017-11-24 Aboca Spa Societa Agricola Composizioni a base di gemme di pioppo e loro usi
IT201700016964A1 (it) * 2017-02-15 2018-08-15 Aboca Spa Societa Agricola Composizione per la tosse
WO2019209228A3 (en) * 2017-12-29 2020-01-23 Montero Gida Sanayi Ve Ticaret Anonim Sirketi Solid oral compositions comprising dried honey and herbal extracts
IT202300016338A1 (it) * 2023-08-01 2025-02-01 Elysium Cell Bio Ita Srl Composizione nutraceutica contenente propoli, verbasco, timo, polifosfati, potassio sorbato e sodio benzoato con attività antivirale (sars-cov-2, influenza a e b, virus erpetici a rna) antinfiammatoria, antibatterica, antimicotica e prebiotica.

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3714940A1 (en) * 2019-03-26 2020-09-30 Schwabe Pharma Italia S.r.l. Pharmaceutical formulation for oral use containing honey and plant extracts with an assayed polysaccharide and mucilage content for the treatment of productive and non-productive coughs and throat diseases
ES2952909A1 (es) * 2022-03-22 2023-11-06 Laboratorios Vinas S A Composición galénica para uso tópico, procedimiento de preparación y uso de la misma en el tratamiento de afecciones de garganta irritada

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4208331A1 (de) * 1991-04-10 1992-10-15 Franz Reichmuth Aufbaupraeparat auf kunsthonigbasis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1748731A (zh) * 2005-10-20 2006-03-22 北京润德康医药技术有限公司 一种咳痰复方制剂及其制备方法
CN101011097A (zh) * 2007-02-02 2007-08-08 董生培 凉茶组合物
EP2217279B1 (en) * 2007-11-21 2017-11-01 The Procter & Gamble Company Preparations useful for treatment of cough
CN102416095B (zh) * 2011-11-21 2013-02-06 湖南时代阳光药业股份有限公司 一种治疗扁桃体炎、咽炎的中药组合物

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4208331A1 (de) * 1991-04-10 1992-10-15 Franz Reichmuth Aufbaupraeparat auf kunsthonigbasis

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
ANONYMOUS: "Blog della Parafarmacia Farma Drugstore del Dott. Baronzio Attilio: LisoNatural come comprare una Maserati al prezzo della Ferrari....", 8 November 2013 (2013-11-08), pages 1 - 4, XP055103951, Retrieved from the Internet <URL:http://farmadrugstore.blogspot.co.uk/2013/11/lisonatural-come-comprare-una-maserati.html> [retrieved on 20140224] *
ANONYMOUS: "Lisonatural", 24 February 2014 (2014-02-24), pages 1 - 2, XP055103947, Retrieved from the Internet <URL:http://web.archive.org/web/20140224131117/http://www.automedicazione.it/View_Document.aspx?IdDocument=8436> [retrieved on 20140224] *
ANONYMOUS: "PLANTS TO COMBAT COLDS & FLU", 1 November 2010 (2010-11-01), pages 1 - 2, XP055103963, Retrieved from the Internet <URL:http://www.livingmedicine.org/projects/pdf/wh_10.pdf> [retrieved on 20140224] *
DATABASE GNPD [online] MINTEL; January 2008 (2008-01-01), ANONYMOUS: "Propolis Syrup", XP002720813, retrieved from www.gnpd.com Database accession no. 846625 *
DATABASE GNPD [online] MINTEL; June 2009 (2009-06-01), ANONYMOUS: "Tannenblut N Kinder", XP002720812, retrieved from www.gnpd.com Database accession no. 1100967 *
DATABASE GNPD [online] MINTEL; May 2012 (2012-05-01), ANONYMOUS: "Honey Herb Pastilles", XP002720811, retrieved from www.gnpd.com Database accession no. 1799599 *
KRAFT K: "PHARMAZIE IN UNSERER ZEIT", vol. 37, 1 November 2008, VCH VERLAGSGESELLSCHAFT, article "Symptomatische Phytotherapie bei Husten Stellenwert pflanzlicher Antitussiva und Expektorantien", pages: 478 - 483
KRAFT K: "Symptomatische Phytotherapie bei Husten Stellenwert pflanzlicher Antitussiva und Expektorantien = Symptomatic phytotherapy in coughs: Importance of plant antitussives and expectorants", PHARMAZIE IN UNSERER ZEIT, VCH VERLAGSGESELLSCHAFT, WEINHEIM, DE, vol. 37, no. 6, 1 November 2008 (2008-11-01), pages 478 - 483, XP009151427, ISSN: 0048-3664, [retrieved on 20081027], DOI: 10.1002/PAUZ.200800287 *
MENALE BRUNO ET AL: "Use of medicinal plants in the South-Eastern area of the Partenio Regional Park (Campania, Southern Italy)", JOURNAL OF ETHNOPHARMACOLOGY, vol. 153, no. 1, 25 February 2014 (2014-02-25), pages 297 - 307, XP028832904, ISSN: 0378-8741, DOI: 10.1016/J.JEP.2014.02.039 *
SNOOPMEDIA GMBH ET AL: "Ricola Honig-Kräuter 75 g", 23 January 2011 (2011-01-23), pages 1 - 4, XP055103922, Retrieved from the Internet <URL:http://web.archive.org/web/20110123211918/http://das-ist-drin.de/Ricola-Honig-Kraeuter-75-g--420140> [retrieved on 20140224] *

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITUA20163755A1 (it) * 2016-05-24 2017-11-24 Aboca Spa Societa Agricola Composizioni a base di gemme di pioppo e loro usi
WO2017203414A1 (en) * 2016-05-24 2017-11-30 Aboca S.P.A. Società Agricola Compositions comprising extract of poplar buds and uses thereof
US11839638B2 (en) 2016-05-24 2023-12-12 Aboca S.P.A. Società Agricola Compositions comprising extract of poplar buds and uses thereof
IT201700016964A1 (it) * 2017-02-15 2018-08-15 Aboca Spa Societa Agricola Composizione per la tosse
WO2018150309A1 (en) * 2017-02-15 2018-08-23 Aboca S.P.A Società Agricola Composition for cough
AU2018220880B2 (en) * 2017-02-15 2020-11-26 Aboca S.P.A Società Agricola Composition for cough
US11154564B2 (en) 2017-02-15 2021-10-26 Aboca S.P.A. Società Agricola Composition for cough
WO2019209228A3 (en) * 2017-12-29 2020-01-23 Montero Gida Sanayi Ve Ticaret Anonim Sirketi Solid oral compositions comprising dried honey and herbal extracts
IT202300016338A1 (it) * 2023-08-01 2025-02-01 Elysium Cell Bio Ita Srl Composizione nutraceutica contenente propoli, verbasco, timo, polifosfati, potassio sorbato e sodio benzoato con attività antivirale (sars-cov-2, influenza a e b, virus erpetici a rna) antinfiammatoria, antibatterica, antimicotica e prebiotica.

Also Published As

Publication number Publication date
EP3060224A1 (en) 2016-08-31
HUE046608T2 (hu) 2020-03-30
US10588933B2 (en) 2020-03-17
CN105764519A (zh) 2016-07-13
EA037173B1 (ru) 2021-02-15
US20160303179A1 (en) 2016-10-20
ES2743210T3 (es) 2020-02-18
CA2928551A1 (en) 2015-04-30
EA201690597A1 (ru) 2016-09-30
EP3060224B1 (en) 2019-07-03
MX374590B (es) 2025-03-06
CA2928551C (en) 2021-09-21
BR112016008876A2 (https=) 2017-08-01
BR112016008876B1 (pt) 2021-09-14
ITRM20130592A1 (it) 2015-04-26
MX2016005359A (es) 2016-12-14
PL3060224T3 (pl) 2020-01-31
PT3060224T (pt) 2019-08-21
CN105764519B (zh) 2019-11-01

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