WO2014146287A1

WO2014146287A1 - Cat urine ph indicating material, health indicating cat litter, and method for preparing health indicating cat litter

Info

Publication number: WO2014146287A1
Application number: PCT/CN2013/073031
Authority: WO
Inventors: 李永兆
Original assignee: 青岛美高集团有限公司
Priority date: 2013-03-22
Filing date: 2013-03-22
Publication date: 2014-09-25

Abstract

Provided are a cat urine power of hydrogen (pH) indicating material, health indicating cat litter, and a method for preparing health indicating cat litter. The cat urine pH indicating material uses silica gel as a carrier, and comprises a pH mixed indicator accounting for 0.001—2% percent of the gross weight of the pH indicating material and a water soluble polymer accounting for 0.5—20% of the gross weight of the pH indicating material, and a rate in weight of methyl red to an indicator A that are comprised in the pH mixed indicator is 1:15-1:1. The health indicating cat litter is formed by a mixture of the pH indicating material and silica gel, and the pH indicating material accounts for 1-20% of the gross weight of the cat litter. Because consistency of a pH indicating material carrier and basic silica gel is ensured in the materials, the pH indicating material is uniformly distributed in cat litter products and can sensitively and stably indicate a pH value of cat urine. The cat litter has a low production cost, no toxin, no radioactivity, a simple and easy preparation process, and an attractive appearance and color.

Description

Cat urine pH indicator material and health indicator cat litter and preparation method thereof

The present invention relates to a pH indicating material and a health indicating cat litter capable of indicating whether a urine value of a mammalian pet (especially a cat) is within a normal range and a preparation method thereof.

Background technique

According to research by animal research institutions at home and abroad, the normal urine of cats is weakly acidic, with a pH between 5.5 and 7.0. The pH of the urine of many cats with disease shifts from the normal range to acidic or alkaline. Cat urine The common cause of abnormal pH is cat urinary tract disease or cat urinary system syndrome. Urine with a high pH tends to cause the formation of magnesium crystals, and urine with a low pH tends to cause the formation of calcium crystals. Therefore, the cat's health can be predicted by examining the pH of the cat's urine so that the pet owner can anticipate certain diseases of the cat.

U.S. Patent No. 6,162,646 provides a basic litter material (e.g., bentonite) to which a pH indicator material based on a polymer foam (especially polyurethane foam) is added for the detection of acidic or alkaline cat urine. To achieve the purpose of preventing cat urinary tract disease. European Patent EP0569232 discloses a cat litter having a pH indicating function, which is added to a bentonite material by a non-absorbent calcium carbonate marble piece, a granite piece or a water-insoluble polymer material (for example, high-crossing) Sodium polyacrylate) As a matrix material, a pH indicating material in which a pH-indicating dye is bonded to a matrix material using a water-soluble polymer. Among such indicator materials, the patent specifically states that the matrix material is preferably a non-absorbent, reflective inert carrier such that the pH indicator dye can be readily encapsulated by the water soluble polymer and retained in the inert carrier (matrix) material. The outer surface; and if a water-absorbent matrix material is used, the water-soluble polymer and the water-soluble pH indicating dye enter the interior of the matrix material and cause waste. Since the patent recommends the use of a non-absorbent matrix material, the water-soluble polymer acts as an adhesive coating after drying to immobilize the pH indicator dye.

The basic cat litter selected in the above two patents is bentonite, and the substrate of the pH indicating material is made of plastic foam, highly crosslinked sodium polyacrylate polymer material or marble or granite flakes. Swelling The disadvantage of soil is that the urine will stick to the cat after it is wet, and the bentonite will have ion exchange with the urine, which may affect the accuracy of the pH indication. While the polymer material itself has the function of adsorbing cat urine, since it is opaque, the water-soluble polymer and/or the water-soluble pH indicating dye enters the inside of the matrix material and causes waste. Although marble and granite have the advantage of being chemically stable, but because they are not able to absorb urine, the urine of the cat will directly penetrate into a large amount of bentonite around it, and the bentonite will immediately agglomerate due to water absorption. The quantity of the pH indicator material is wrapped up, which affects the color development and color change effect of the cat litter as a whole. Even the method of manually spraying the pH indicator material on the surface of the cat litter has to be taken, but the problem is that the cat is After excretion, it will bury your urine, and the pH indicator on the surface will be buried in bentonite and waste. Moreover, the pH indicating materials disclosed in the above two patents differ from the basic litter materials in terms of density, which may result in uneven distribution of the pH indicating material in the litter, and also affect the color development and color change effect of the cat litter as a whole. Summary of the invention

The technical problem to be solved by the present invention is to provide a cat urine pH indicating material and a health indicating cat litter and a preparation method thereof, wherein the pH indicating material in the cat litter product is evenly distributed, and can sensitively and stably indicate the pH of the cat urine. PH ≤ 5.0 color from light red to bright red, PH between 5.0-7.0 is orange to brownish yellow, PH ≥ 7.0 is light green to blue green.

The invention provides a cat urine pH indicating material, which comprises a silica gel as a carrier, a pH mixing indicator containing 0.001-2% of the total weight of the pH indicating material, and 0.5-20% of a water-soluble polymer, wherein the pH mixing indicator Includes methyl red and indicator A in a weight ratio of 1: 15-1:1.

The technical solution of the present invention is:

The pH mixing indicator accounts for 0.001-2%, preferably 0.002-1.5% of the total weight of the pH indicating material; the water-soluble polymer accounts for 0.5-20%, preferably 1.0-10% of the total weight of the pH indicating material; pH mixing indicator The weight ratio of methyl red to indicator A is 1: 15-1:1, preferably 1:10-1:2.

The water-soluble polymer may be one of polyvinylpyrrolidone, polyethylene glycol, propylene glycol, glycerin, or polyvinyl alcohol or a mixture of any two or more thereof. The polyvinylpyrrolidone (PVP) in the water-soluble polymer preferably has a weight average molecular weight ranging from 2,000 to 500,000; polyethylene glycol (PEG) The weight average molecular weight preferably ranges from 200 to 20,000, more preferably from 200 to 1,500; and the polyvinyl alcohol (PVA) weight average molecular weight preferably ranges from 1,000 to 35,000.

The carrier silica gel is a common silica gel product. Preferably, the block silica gel has an average pore volume of 0.5-1.8 ml/g, a bulk density of 200-700 g/L, and a particle size of 0.5-4 mm _;

The invention provides a pH indicating silica gel litter prepared by using the foregoing pH indicating material, which is characterized by comprising a mixture of a pH indicating material and a base silica gel, wherein the pH indicating material accounts for 1-20% of the total weight of the silica gel litter, preferably 2 -15%.

The base silica gel is a common silica gel product, preferably used as a block silica gel for cat litter, having an average pore volume of 0.5-1.8 ml/g, a bulk density of 200-700 g/L, and a particle size of 0.5-4 mm; The silica gel as a carrier in the pH indicating material may be the same or different in pore structure such as a surface or a pore volume. Preferably, a block silica gel having the same specifications as the silica gel in the pH indicator material is used.

When the silica gel litter containing the pH indicating material of the present invention is used, the acidic pH of the pet urine of the problem is about 6.0 or less. For example, 5.0, the methyl red color changes from yellow to red. Therefore, a red appearance shows that the cat excretes the problematic acidic urine. When the problematic pet's urine is alkaline pH, it may show that the cat may have urinary syndrome, for example, when the pH is between 7.0 and 8.0, the indicator A will change from yellow to blue or purple, plus yellow. Methyl red, pH mixed indicator will appear green to blue-violet.

A method for preparing a pH indicator silica gel litter includes the following steps:

a) dissolving the amount of methyl red, indicator A and water-soluble polymer into an alkali solution to prepare an infusion solution; or pre-dissolving methyl red and indicator A into an alkaline solution to prepare a pH indicator Solution solution, then dissolving the water-soluble polymer into water, and then mixing the two to prepare a dip solution; in the prepared dip solution, the pH indicator is 0.05-1.5 wt%; water-soluble polymer The weight concentration of the aqueous solution is from 1 to 10% by weight;

(b) The carrier silica gel is immersed in the dyeing solution for 3-8 hours, and then taken out and dried at a temperature of 60-140 ° C to become a pH indicating material.

(c) Mixing the pH indicator material prepared in (b) with the untreated base silica gel. In the above step (a), the amount of the mixed solution of sodium hydroxide and water, the amount of sodium hydroxide (or an alkaline solution mainly composed of sodium hydroxide), and the amount of water are preferably 1:1000. In the formulated dip solution, the weight concentration of the pH indicator is preferably from 0.1 to 1.0% by weight; and the concentration of the aqueous solution of the water-soluble polymer is preferably from 2 to 8% by weight.

In the above step (b), the drying temperature is preferably 80-110 ° C; the preferred temperature is more favorable for ensuring the health indication of the orange color of the cat litter, which is advantageous for color development accuracy.

The preparation method of the silica gel cat litter of the present invention may be carried out by using the above-mentioned step, or by first impregnating the carrier silica gel with an aqueous solution of a water-soluble polymer for a period of time, and then adding a pH indicator solution for dip dyeing, wherein the carrier is impregnated with the aqueous solution of the water-soluble polymer. The time of the silica gel is not critical and can be carried out from a few minutes to a few hours by simply dipping the water soluble polymer into a portion of the silica gel. This preparation method has the effect of allowing the pH indicator to enter the internal pores of the carrier silica less, which can increase the sensitivity of the pH indicator material to color development when it encounters pet excrement.

The health indicator silica gel litter of the present invention overcomes the deficiency of the existing pH indicating cat litter, and the carrier of the pH indicating material and the basic litter are all made of the same material, silica gel, to make the dispersion of the two more uniform. Moreover, because of the chemical stability of silica gel, it does not have the significant ion exchange properties like bentonite, so it does not interfere with the pH of cat urine and improves the test accuracy.

The pH indicator material in the silica gel cat litter of the present invention is silica gel loaded with a water soluble polymer and two pH indicators. One of the indicators has a significant color change when detecting a solution having a pH of less than 5.0, and another indicator has a significant color change when detecting a solution having a pH greater than 7.0. In particular, it is used as a cat litter additive to indicate that cat urine is acidic pH (pH below approximately 5.6), or to indicate cat urinary system syndrome (cat urine pH 7.4 or above).

In this manner, when the urine is brought into contact with the pH indicating silicone cat litter of the present invention, it is absorbed by the pH indicating material uniformly dispersed therein, and with the pH supported on the surface thereof and a small portion entering the inside thereof. The mixed indicator is contacted so that it indicates the pH of the cat's urine. Urine at different pH values will cause the pH indicator material to show a different color. Moreover, since the silica gel itself is transparent, even a pH mixing indicator that has entered the silica gel carrier of the pH indicator material does not waste, and It is a change in color that is reflected by the refraction of light. Moreover, since the water-soluble polymer in the present invention can uniformly disperse the pH mixing indicator (dye:) in the solution at the time of preparation, on the other hand, a barrier film can be formed after the pH indicating material is dried, which can prevent The pH mixing indicator (dye) diffuses and penetrates into the internal pores of the carrier silica gel, so that most of the pH indicator dyes are supported on the surface of the carrier silica gel, which increases the sensitivity of color development.

The silica gel litchi containing the pH indicating material of the present invention has significant advantages over the prior art pH indicating cat litter. As described above, since it ensures the consistency of the pH indicating material carrier and the basic litter in the material, the pH indicating material in the litter product is uniformly distributed, and the pH of the cat urine can be sensitively and stably indicated; PH of the present invention The indicator material is more obvious in terms of coloration indication, PH≤5.0 color from light red to bright red, PH between 5.0-7.0 is orange to brownish yellow, PH≥7.0 is light green to blue-green; the product of the invention has low production cost Non-toxic, non-radioactive, simple and easy to prepare, and beautiful in appearance.

detailed description

The invention is described in detail below with the aid of the accompanying drawings, but it should be noted that these examples are only intended to illustrate the invention and not to limit the invention.

Example 1

5 kg of pore volume of 0.91 ml / g, bulk density of 386g / L, particle size of 0.7-1.5mm block of silica gel into the prepared pH indicator dyeing solution, the pH indicator dyeing solution from 5L concentration of 0.3 The wt% methyl red and indicator A solution (the weight ratio of methyl red to indicator A is 1/10), and 10L of a 6wt% aqueous solution of PEG-1500 are mixed, after soaking for 3 hours, The moisture was dried to 4 wt% or less at 80 ° C, and the pH indicating material contained 0.1 wt% of a mixed indicator, and 4 wt% of PEG-1500. The obtained pH indicating material is mixed with the same specification of silica gel so that the weight indicating material is 5 wt%, and the performance test data of the silica gel litter is shown in Table 1: Table 1

Example 2

3 kg of pore volume of 1.21 ml / g, bulk density of 356 g / L, particle size of 2-4 mm of block silica gel into the prepared pH indicator dyeing solution, the pH indicator dyeing solution from 4L concentration of 0.9wt % methyl red and indicator A solution (methyl red and indicator A weight ratio is 1 / 6), and 5L concentration of 9wt% aqueous solution of PEG-200 mixed, soaked for 4 hours, at 90 The moisture was dried to 4 wt% or less, and the pH indicating material contained 0.4 wt% of a mixed indicator, and 5 wt% of PEG-200. The obtained pH indicator material is further mixed with silica gel of the same specification, so that the weight of the pH indicator material is 3 wt%, and the performance test data of the silica gel litter is shown in Table 2: Table 2

Example 3

1 kg of pore volume of 0.97 ml / g, bulk density of 364g / L, particle size of 5-8mm block of silica gel into the prepared pH indicator dyeing solution, the pH indicator dyeing solution by 1.5L concentration 0.6 wt% of methyl red and indicator A solution (weight ratio of methyl red to indicator A is 1/2), and 3 L of a 6 wt% aqueous solution of PVP-5000 are mixed, after soaking for 6 hours, The moisture was dried to below 4 wt% at 110 ° C. The pH indicating material contained 0.2 wt% of the mixed indicator and 4 wt% of PVP-5000. The obtained pH indicator material is mixed with the same specification of silica gel so that the weight indicator material has a weight percentage of 8 wt%, and the performance test data of the silica gel litter is shown in Table 3: Table 3

Example 4

3 kg of pore volume of 1.41 ml / g, bulk density of 235g / L, particle size of 0.7-1.5mm block of silica gel into the prepared pH indicator dyeing solution, the pH indicator dyeing solution from 8L concentration of 0.6 Wt% methyl red and indicator A solution (weight ratio of methyl red to indicator A is 1/4), and 4L of 12% by weight aqueous solution of propylene glycol, after soaking for 5 hours, at 95 ° C dries the moisture to below 4 wt%, the pH indicating material containing 0.4 wt% of the mixed indicator, 4 wt% of propylene glycol. The obtained pH indicating material is mixed with the same specification of silica gel so that the weight indicating material is 6 wt%, and the performance test data of the silica gel litter is shown in Table 4: Table 4

Example 5

2kg of pore volume of 1.03ml / g, bulk density of 388g / L, particle size of 2-4mm block of silica gel into the prepared pH indicator dyeing solution, the pH indicator dyeing solution from 3L concentration of lwt% Methyl red and indicator A solution (methyl red and indicator A weight ratio is 1 / 8), and 3L concentration of 10% by weight of glycerol aqueous solution mixed, soaked for 8 hours, at 85 ° C. The moisture is dried to below 4 wt%, and the pH indicating material contains 0.5% by weight of a mixed indicator, and 5% by weight of glycerin. The obtained pH indicator material is mixed with the same specification of silica gel so that the weight percentage of the pH indicator material is 3 wt%, and the performance test data of the silica gel litter is shown in Table 5:

Example 6

2kg of pore volume of 0.89ml / g, bulk density of 391g / L, particle size of 0.7-1.5mm block of silica gel into 4L of prepared pH indicator dyeing solution, the pH indicator dyeing solution contains 0.5wt% methyl red mixed with indicator A indicator (methylene red and indicator A weight ratio is 1/6), 5wt% PVP-10000, after soaking for 3 hours, drying moisture at 100 °C Up to 4 wt% or less, this pH indicating material contained 0.5 wt% of a mixed indicator, and 5 wt% of PVP-10000. The obtained pH indicating material is mixed with the same specification of silica gel so that the weight percentage of the pH indicating material is 4 wt%, and the performance test data of the silica gel litter is shown in Table 6: Table 6

Claims

claims

1. A cat urine pH indicating material, characterized in that it uses silica gel as a carrier, contains 0.001-2% of the total weight of the pH indicating material as a pH mixed indicator and 0.5-20% of a water-soluble polymer, and its pH mixture The indicator includes methyl red and indicator A in a weight ratio of 1:15-1:1.

2. The cat urine pH indicating material according to claim 1, characterized in that: the indicator A is phenol red, cresol red, bromocresol violet, p-bromobenzenesulfonyl chloride, Congo red, methyl orange , bromochlorophenol blue, p-ethoxy chrysanthemum orange, naphthalene red, bromocresol green, tetrabromophenol blue, resorcinol blue, litmus, chlorophenol red, benzoyl G, litmus essence, bromophenol Red, tetrabromophenol sulfone phenolphthalein, neutral red, m-cresol, 2,4-dinitrophenyl acetate, nasturtium orange, thymol blue, o-cresolphthalein, thymolphthalein, nile blue, turmeric One or a mixture of several of dimethylaminoazobenzene, metaamine yellow, methyl violet 6B, resin sky clear, and xylenol blue.

3. The cat urine pH indicating material according to claim 2, characterized in that: the water-soluble polymer adopts one of polyvinylpyrrolidone, polyethylene glycol, polyvinyl alcohol, propylene glycol or glycerol. species or a mixture of several species.

4. The cat urine pH indicating material according to claim 3, characterized in that: the weight average molecular weight of polyvinylpyrrolidone ranges from 2000 to 500000, the weight average molecular weight of polyethylene glycol ranges from 200 to 20000, and polyvinyl alcohol The weight average molecular weight range is 1000-35000.

5. The cat urine pH indicating material according to claim 1, characterized in that: the pH mixed indicator accounts for 0.002-1.5% of the total weight of the pH indicating material, and the water-soluble polymer accounts for 1.0% of the total weight of the pH indicating material. -10%, the weight ratio of methyl red and indicator A in the pH mixed indicator is 1:10-1:2.

6. The cat urine pH indicating material according to claim 1, characterized in that: the carrier silica gel is block silica gel, its average pore volume is 0.5-1.8ml/g, and its bulk density is 200-700g/L. The particle size is 0.5-4mm.

7. A health-indicating cat litter using the cat urine pH-indicating material of any one of claims 1 to 6, characterized in that it is composed of a mixture of pH-indicating material and silica gel, wherein the pH-indicating material accounts for the total weight of the cat litter 1-20%.

8. A method for preparing the health-indicating cat litter described in claim 7, characterized by comprising the following steps:

a) Dissolve the stated amount of methyl red, indicator A and water-soluble polymer into an alkaline solution to make a dip dye solution, or pre-dissolve methyl red and indicator A into an alkaline solution to make a pH indicator solution, then dissolve the water-soluble polymer into water, and then mix the two to prepare a dip-dye solution; in the prepared dip-dye solution, the weight concentration of the pH indicator is 0.05-1.5wt%; the water-soluble polymer aqueous solution The weight concentration is 1-10wt%;

(b) Dip the carrier silica gel into the dip dyeing solution for 3-8 hours, then take it out and dry it at a temperature of 60-140°C to become a pH indicating material;

(c) Mix the pH indicating material prepared in (b) with basic silica gel.

9. The method of health-indicating cat litter according to claim 8, characterized in that: in step (a), the alkali solution is an aqueous hydroxide solution, and the weight ratio of hydroxide and water is preferably 1:1000; In the prepared dip dyeing solution, the weight concentration of the pH indicator is preferably 0.1-1.0wt%; the weight concentration of the water-soluble polymer aqueous solution is preferably 2-8wt%.

10. The method of health-indicating cat litter according to claim 8, characterized in that: in step (b), the drying temperature is preferably 80-110°C.